Motif ID: PATZ1.p2

Z-value: 1.701


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
Patz1 56218 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Patz1chr11_+_31891570.208.2e-03Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_132602648 63.462 NM_009749
Bex2
brain expressed X-linked 2
chr4_+_137283714 48.568 Rap1gap
Rap1 GTPase-activating protein
chr1_+_66515003 39.572 NM_175510
Unc80
unc-80 homolog (C. elegans)
chr4_-_151235861 37.851 NM_001081557
NM_001195565
Camta1

calmodulin binding transcription activator 1

chr3_+_156224757 36.391 NM_001039094
NM_177274
Negr1

neuronal growth regulator 1

chr15_+_89330287 34.481 NM_021423
Shank3
SH3/ankyrin domain gene 3
chr7_+_4642529 33.961 NM_001003920
NM_001168572
Brsk1

BR serine/threonine kinase 1

chr7_-_134164487 32.776 Prrt2
proline-rich transmembrane protein 2
chr5_+_37633353 32.473 Crmp1
collapsin response mediator protein 1
chr14_-_30534966 30.798 NM_009785
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr5_+_37633317 29.496 NM_001136058
Crmp1
collapsin response mediator protein 1
chr15_-_75397030 28.912 NM_001135689
Ly6h
lymphocyte antigen 6 complex, locus H
chr7_-_134164627 28.678 NM_001102563
Prrt2
proline-rich transmembrane protein 2
chr9_-_86775154 24.200 NM_013669
Snap91
synaptosomal-associated protein 91
chr16_-_18629938 23.607 NM_213614
Sept5
septin 5
chr7_-_25857275 23.575 NM_008168
Grik5
glutamate receptor, ionotropic, kainate 5 (gamma 2)
chr11_-_70846926 23.388 6330403K07Rik
RIKEN cDNA 6330403K07 gene
chr2_-_73224394 22.618 NM_001080707
NM_001190297
Gpr155

G protein-coupled receptor 155

chr17_+_24625943 22.544 Caskin1
CASK interacting protein 1
chr7_+_134094045 21.878 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr9_+_110147867 21.813 Cspg5
chondroitin sulfate proteoglycan 5
chr7_+_31076852 21.746 Clip3
CAP-GLY domain containing linker protein 3
chr15_-_75397243 21.319 NM_001135688
Ly6h
lymphocyte antigen 6 complex, locus H
chr14_+_67530044 20.907 NM_175498
Pnma2
paraneoplastic antigen MA2
chr16_-_20621287 20.512 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr4_+_138011061 20.423 NM_025451
Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_-_88599560 19.824 NM_007755
Cpeb1
cytoplasmic polyadenylation element binding protein 1
chr10_-_126700105 19.747 Kif5a
kinesin family member 5A
chr13_+_104899814 19.530 Sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr4_-_91038638 19.468 Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr9_-_86775282 19.056 Snap91
synaptosomal-associated protein 91
chr10_-_70062025 18.902 NM_178621
Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr7_-_112729716 18.824 Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr10_-_79602040 18.805 Dos
downstream of Stk11
chr8_+_86424565 18.748 Lphn1
latrophilin 1
chr10_-_70061996 18.711 Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr18_-_16967100 18.706 Cdh2
cadherin 2
chr14_-_55734213 18.573 NM_001003829
Jph4
junctophilin 4
chr7_-_31230564 17.915 Aplp1
amyloid beta (A4) precursor-like protein 1
chr19_+_6341137 17.742 NM_009006
Map4k2
mitogen-activated protein kinase kinase kinase kinase 2
chr9_+_106356125 17.711 NM_021567
Pcbp4
poly(rC) binding protein 4
chr7_+_64846558 17.681 Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr17_-_57226987 17.656 NM_009451
Tubb4
tubulin, beta 4
chr15_-_98638230 17.638 Ddn
dendrin
chr15_+_98465193 17.214 NM_007581
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr17_+_37182910 17.176 NM_019439
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr8_+_125935441 16.725 NM_023279
Tubb3
tubulin, beta 3
chr7_+_133920438 16.679 NM_025347
NM_026875
Ypel3

yippee-like 3 (Drosophila)

chr18_-_16967557 16.662 NM_007664
Cdh2
cadherin 2
chr11_-_119908236 16.547 NM_001198785
NM_007377
Aatk

apoptosis-associated tyrosine kinase

chr3_+_34548916 16.472 NM_011443
Sox2
SRY-box containing gene 2
chr3_-_8666930 16.416 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr11_+_69831951 16.363 NM_001109752
NM_007864
Dlg4

discs, large homolog 4 (Drosophila)

chr6_-_122289630 16.332 Phc1
polyhomeotic-like 1 (Drosophila)
chr11_+_104092809 16.173 Mapt
microtubule-associated protein tau
chr7_-_28181562 16.087 Spnb4
spectrin beta 4
chr4_-_91038729 16.053 NM_010486
NM_207686
Elavl2

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)

chr14_-_55735114 15.992 NM_177049
Jph4
junctophilin 4
chr7_+_64846528 15.951 NM_008071
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr10_-_83903215 15.823 NM_001004363
Nuak1
NUAK family, SNF1-like kinase, 1
chr5_+_37637027 15.800 NM_007765
Crmp1
collapsin response mediator protein 1
chr13_+_104899869 15.620 NM_144838
Sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr7_-_31319977 15.563 NM_178252
Arhgap33
Rho GTPase activating protein 33
chr8_+_125935470 15.407 Tubb3
tubulin, beta 3
chr2_-_130468507 15.407 NM_197945
Prosapip1
ProSAPiP1 protein
chr13_-_78337844 15.218 Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr7_+_31076771 15.058 NM_001081114
Clip3
CAP-GLY domain containing linker protein 3
chr7_+_133966816 15.030 NM_029978
Fam57b
family with sequence similarity 57, member B
chr17_+_86567513 15.015 Prkce
protein kinase C, epsilon
chr2_+_71819264 15.005 NM_019688
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr3_-_57651409 14.923 Pfn2
profilin 2
chr15_+_74346835 14.912 Bai1
brain-specific angiogenesis inhibitor 1
chr15_+_99501148 14.813 NM_009597
Accn2
amiloride-sensitive cation channel 2, neuronal
chr15_+_98465328 14.709 Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr9_+_43851466 14.614 NM_009382
Thy1
thymus cell antigen 1, theta
chr11_+_104092793 14.316 Mapt
microtubule-associated protein tau
chr11_+_101329615 14.231 NM_009708
Rnd2
Rho family GTPase 2
chr2_+_136539143 14.078 NM_011428
Snap25
synaptosomal-associated protein 25
chr19_+_4099973 14.057 NM_001136078
Pitpnm1
phosphatidylinositol transfer protein, membrane-associated 1
chr18_-_25912453 13.923 NM_001146292
NM_001146293
NM_001146294
NM_001146295
NM_001174074
NM_133195
Celf4





CUGBP, Elav-like family member 4





chr2_-_91772424 13.876 NM_010784
Mdk
midkine
chr10_-_76424645 13.864 Pcbp3
poly(rC) binding protein 3
chr6_+_118016385 13.855 NM_027526
Rasgef1a
RasGEF domain family, member 1A
chr19_-_5098498 13.853 Cnih2
cornichon homolog 2 (Drosophila)
chr19_+_6418755 13.821 Nrxn2
neurexin II
chr11_-_59263437 13.807 NM_144521
Snap47
synaptosomal-associated protein, 47
chr4_-_150482562 13.694 Camta1
calmodulin binding transcription activator 1
chrX_+_132804865 13.679 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_132804834 13.667 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr4_-_128798939 13.583 NM_001130419
Hpca
hippocalcin
chr6_-_124813720 13.562 Gpr162
G protein-coupled receptor 162
chr3_-_8667013 13.534 NM_010423
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chrX_+_132804791 13.513 NM_001110233
NM_001110234
NM_009750
Ngfrap1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr11_+_69832336 13.501 Dlg4
discs, large homolog 4 (Drosophila)
chr17_-_24826812 13.480 Syngr3
synaptogyrin 3
chr19_-_5098486 13.420 Cnih2
cornichon homolog 2 (Drosophila)
chr17_+_24625709 13.405 NM_027937
Caskin1
CASK interacting protein 1
chr18_+_38115192 13.274 NM_153793
Rell2
RELT-like 2
chrX_+_133200913 13.271 NM_001029978
Tceal3
transcription elongation factor A (SII)-like 3
chr7_+_19868009 13.195 NM_013648
Rtn2
reticulon 2 (Z-band associated protein)
chr11_+_101329457 13.130 Rnd2
Rho family GTPase 2
chr13_+_42804911 13.090 NM_001005740
Phactr1
phosphatase and actin regulator 1
chr4_+_129662110 13.082 Bai2
brain-specific angiogenesis inhibitor 2
chr11_+_104092749 12.944 NM_001038609
NM_010838
Mapt

microtubule-associated protein tau

chr4_-_147533696 12.815 NM_001161851
Fbxo44
F-box protein 44
chr9_+_21741435 12.811 BC018242
cDNA sequence BC018242
chr3_-_8666985 12.792 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr17_-_24826873 12.698 NM_011522
Syngr3
synaptogyrin 3
chr1_+_74379182 12.644 NM_019999
Pnkd
paroxysmal nonkinesiogenic dyskinesia
chr5_-_21850490 12.626 NM_011261
Reln
reelin
chr7_+_4071171 12.560 Ttyh1
tweety homolog 1 (Drosophila)
chrX_+_132804857 12.521 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr4_-_147534144 12.469 NM_001161852
NM_173401
Fbxo44

F-box protein 44

chr1_-_125942073 12.297 NM_199021
Dpp10
dipeptidylpeptidase 10
chr6_-_124718354 12.186 Eno2
enolase 2, gamma neuronal
chr9_+_103014279 12.161 Rab6b
RAB6B, member RAS oncogene family
chr15_-_98638348 12.078 NM_001013741
Ddn
dendrin
chr2_-_32702610 12.071 Stxbp1
syntaxin binding protein 1
chr14_+_3049284 12.050 NM_001177715
NM_001177714
Gm2897

predicted gene 2897

chr4_+_101223198 11.993 NM_001164583
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr4_-_41587334 11.970 NM_027147
Enho
energy homeostasis associated
chr15_+_74346853 11.953 Bai1
brain-specific angiogenesis inhibitor 1
chr9_+_103014374 11.925 NM_173781
Rab6b
RAB6B, member RAS oncogene family
chr7_-_31699850 11.870 NM_010758
Mag
myelin-associated glycoprotein
chr10_-_115910911 11.815 Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr10_+_127631656 11.733 NM_001033264
Gls2
glutaminase 2 (liver, mitochondrial)
chr3_+_95985065 11.514 NM_022030
Sv2a
synaptic vesicle glycoprotein 2 a
chr2_-_52532100 11.502 NM_001037099
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr11_-_61393108 11.395 NM_010148
Epn2
epsin 2
chrX_+_97972559 11.365 NM_001177780
Dlg3
discs, large homolog 3 (Drosophila)
chr14_-_68742863 11.267 Nefm
neurofilament, medium polypeptide
chr4_+_126846429 11.256 NM_198618
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr14_-_21613162 11.208 NM_001039138
NM_001039139
NM_178597
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr15_+_87455659 11.156 NM_134096
Fam19a5
family with sequence similarity 19, member A5
chr12_-_81537261 11.146 Dcaf5
DDB1 and CUL4 associated factor 5
chr6_-_124813922 11.094 NM_013533
Gpr162
G protein-coupled receptor 162
chr18_-_16967754 10.996 Cdh2
cadherin 2
chr8_-_126039287 10.989 NM_001170975
NM_001170976
NM_028146
Dbndd1


dysbindin (dystrobrevin binding protein 1) domain containing 1


chr3_+_84619399 10.956 NM_001177773
Fbxw7
F-box and WD-40 domain protein 7
chrX_-_98615096 10.922 NM_001177985
NM_001177986
Zmym3

zinc finger, MYM-type 3

chr10_+_74429876 10.912 NM_010311
Gnaz
guanine nucleotide binding protein, alpha z subunit
chr2_+_90725895 10.906 NM_026161
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr2_-_32702729 10.811 NM_009295
NM_001113569
Stxbp1

syntaxin binding protein 1

chrX_+_5624624 10.794 NM_021431
Nudt11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr16_+_5885447 10.790 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_+_19876447 10.747 NM_001025364
Rtn2
reticulon 2 (Z-band associated protein)
chr7_-_31836457 10.745 NM_022007
Fxyd7
FXYD domain-containing ion transport regulator 7
chr16_+_35154935 10.730 Adcy5
adenylate cyclase 5
chr1_+_174271397 10.671 Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chrX_+_71550669 10.598 Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr15_-_95358306 10.598 Nell2
NEL-like 2 (chicken)
chr18_-_16966954 10.575 Cdh2
cadherin 2
chr14_-_7859962 10.573 NM_001164727
Gm10406
predicted gene 10406
chr8_-_89996089 10.571 Cbln1
cerebellin 1 precursor protein
chr7_-_31230463 10.566 Aplp1
amyloid beta (A4) precursor-like protein 1
chr15_-_25343483 10.548 NM_027395
Basp1
brain abundant, membrane attached signal protein 1
chr11_-_90252208 10.496 Hlf
hepatic leukemia factor
chr8_+_96334879 10.457 Gnao1
guanine nucleotide binding protein, alpha O
chr11_-_59263508 10.409 Snap47
synaptosomal-associated protein, 47
chr3_+_136333251 10.396 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr7_-_17200285 10.389 NM_172739
Grlf1
glucocorticoid receptor DNA binding factor 1
chr12_+_109572514 10.310 NM_010010
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr10_+_40603330 10.240 NM_031877
Wasf1
WASP family 1
chr17_-_66799086 10.239 NM_001114098
NM_172963
1110012J17Rik

RIKEN cDNA 1110012J17 gene

chr8_-_126039251 10.236 Dbndd1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr5_+_31117077 10.217 NM_133350
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr2_+_92439758 10.208 NM_023850
Chst1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr16_+_35155621 10.152 NM_001012765
Adcy5
adenylate cyclase 5
chr2_-_167014273 10.120 NM_008420
Kcnb1
potassium voltage gated channel, Shab-related subfamily, member 1
chr2_-_165060188 10.109 NM_174988
Cdh22
cadherin 22
chr14_-_68743060 10.096 NM_008691
Nefm
neurofilament, medium polypeptide
chr5_-_139605617 10.064 NM_008923
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr7_-_52622373 10.057 NM_029741
Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr6_-_124813970 10.041 Gpr162
G protein-coupled receptor 162
chr7_-_31230577 10.030 NM_007467
Aplp1
amyloid beta (A4) precursor-like protein 1
chr15_+_99125768 9.967 NM_018786
Prpf40b
PRP40 pre-mRNA processing factor 40 homolog B (yeast)
chr10_-_115910578 9.932 NM_021452
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr2_+_48805027 9.897 NM_029924
Mbd5
methyl-CpG binding domain protein 5
chr4_-_68615382 9.881 NM_019967
Dbc1
deleted in bladder cancer 1 (human)
chr18_+_35989376 9.837 NM_133687
Cxxc5
CXXC finger 5
chr19_-_4283047 9.797 Ankrd13d
ankyrin repeat domain 13 family, member D
chr5_-_23835349 9.788 Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr10_-_76424664 9.745 NM_021568
Pcbp3
poly(rC) binding protein 3
chr17_-_46817800 9.719 NM_001163729
NM_027910
Klhdc3

kelch domain containing 3

chr7_-_17501647 9.687 Calm3
calmodulin 3
chr3_-_138738020 9.624 Rap1gds1
RAP1, GTP-GDP dissociation stimulator 1
chr3_-_156224638 9.609 4930570G19Rik
RIKEN cDNA 4930570G19 gene
chr14_-_71035662 9.554 Epb4.9
erythrocyte protein band 4.9
chr12_-_73509925 9.527 NM_153457
Rtn1
reticulon 1
chr13_-_55589463 9.506 Dbn1
drebrin 1
chr12_+_73186837 9.481 Jkamp
JNK1/MAPK8-associated membrane protein
chr8_-_4259126 9.389 NM_183315
Ctxn1
cortexin 1
chr19_-_5098381 9.345 NM_009920
Cnih2
cornichon homolog 2 (Drosophila)
chr2_-_165060352 9.312 Cdh22
cadherin 22
chr7_-_52622167 9.258 Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr9_+_103014445 9.253 Rab6b
RAB6B, member RAS oncogene family
chr1_+_160292665 9.251 Astn1
astrotactin 1
chr7_+_108599740 9.241 NM_001143849
Pde2a
phosphodiesterase 2A, cGMP-stimulated
chr11_+_68901989 9.228 Vamp2
vesicle-associated membrane protein 2
chr17_-_25570721 9.209 NM_001163691
NM_021415
Cacna1h

calcium channel, voltage-dependent, T type, alpha 1H subunit


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.19 4.68e-28 GO:0044237 cellular metabolic process
1.25 7.60e-27 GO:0019222 regulation of metabolic process
1.16 1.90e-26 GO:0008152 metabolic process
1.18 1.11e-25 GO:0044238 primary metabolic process
1.26 1.16e-24 GO:0031323 regulation of cellular metabolic process
1.26 9.20e-24 GO:0080090 regulation of primary metabolic process
1.21 4.04e-22 GO:0044260 cellular macromolecule metabolic process
1.27 3.96e-20 GO:0016043 cellular component organization
1.28 4.84e-20 GO:0048518 positive regulation of biological process
1.25 1.64e-19 GO:0051179 localization
1.27 2.38e-19 GO:0051171 regulation of nitrogen compound metabolic process
1.29 3.48e-19 GO:0048522 positive regulation of cellular process
1.24 7.64e-19 GO:0060255 regulation of macromolecule metabolic process
1.18 1.10e-18 GO:0043170 macromolecule metabolic process
1.27 1.15e-18 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 5.68e-18 GO:0071840 cellular component organization or biogenesis
1.30 1.97e-17 GO:0071842 cellular component organization at cellular level
1.26 2.13e-17 GO:0031326 regulation of cellular biosynthetic process
1.26 3.77e-17 GO:0009889 regulation of biosynthetic process
1.42 3.80e-17 GO:0007399 nervous system development
1.28 5.22e-17 GO:0048731 system development
1.23 5.52e-17 GO:0032502 developmental process
1.27 9.04e-17 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.26 2.10e-16 GO:0051234 establishment of localization
1.24 2.28e-16 GO:0007275 multicellular organismal development
1.26 2.98e-16 GO:0048856 anatomical structure development
1.26 3.25e-16 GO:0010468 regulation of gene expression
1.25 8.79e-16 GO:0006810 transport
1.26 9.95e-16 GO:0010556 regulation of macromolecule biosynthetic process
1.27 5.04e-15 GO:0071841 cellular component organization or biogenesis at cellular level
1.27 5.15e-15 GO:0051252 regulation of RNA metabolic process
1.27 6.99e-15 GO:0006355 regulation of transcription, DNA-dependent
1.27 2.40e-14 GO:0044267 cellular protein metabolic process
1.31 2.41e-13 GO:0006464 protein modification process
1.28 2.57e-13 GO:0030154 cell differentiation
1.27 4.97e-13 GO:0048869 cellular developmental process
1.25 9.34e-13 GO:0048519 negative regulation of biological process
1.33 1.47e-12 GO:0023051 regulation of signaling
1.32 3.73e-12 GO:0065009 regulation of molecular function
1.32 9.90e-12 GO:0009653 anatomical structure morphogenesis
1.28 1.06e-11 GO:0043412 macromolecule modification
1.31 1.27e-11 GO:0051239 regulation of multicellular organismal process
1.20 1.61e-11 GO:0009058 biosynthetic process
1.25 2.45e-11 GO:0048523 negative regulation of cellular process
1.20 7.57e-11 GO:0044249 cellular biosynthetic process
1.07 7.85e-11 GO:0009987 cellular process
1.36 2.73e-10 GO:0032879 regulation of localization
1.40 3.30e-10 GO:0022008 neurogenesis
1.26 4.68e-10 GO:0065008 regulation of biological quality
1.41 5.37e-10 GO:0048699 generation of neurons
1.26 6.52e-10 GO:0006351 transcription, DNA-dependent
1.26 6.63e-10 GO:0032774 RNA biosynthetic process
1.21 7.10e-10 GO:0019538 protein metabolic process
1.32 1.07e-09 GO:0033036 macromolecule localization
1.42 1.33e-09 GO:0016265 death
1.49 1.36e-09 GO:0030182 neuron differentiation
1.42 1.68e-09 GO:0008219 cell death
1.17 1.86e-09 GO:0006807 nitrogen compound metabolic process
1.17 2.11e-09 GO:0034641 cellular nitrogen compound metabolic process
1.44 2.67e-09 GO:0012501 programmed cell death
1.38 2.75e-09 GO:0048468 cell development
1.33 6.91e-09 GO:0035556 intracellular signal transduction
1.53 7.37e-09 GO:0048666 neuron development
1.34 7.96e-09 GO:0051641 cellular localization
1.60 1.02e-08 GO:0031175 neuron projection development
1.26 1.18e-08 GO:0048583 regulation of response to stimulus
1.31 1.39e-08 GO:0009966 regulation of signal transduction
1.21 1.57e-08 GO:0009059 macromolecule biosynthetic process
1.27 2.43e-08 GO:0006996 organelle organization
1.33 4.08e-08 GO:0006793 phosphorus metabolic process
1.33 4.67e-08 GO:0006796 phosphate metabolic process
1.20 5.00e-08 GO:0034645 cellular macromolecule biosynthetic process
1.42 5.00e-08 GO:0006915 apoptosis
1.30 5.94e-08 GO:0050790 regulation of catalytic activity
1.32 6.35e-08 GO:0010941 regulation of cell death
1.32 7.26e-08 GO:0050793 regulation of developmental process
1.47 9.01e-08 GO:0030030 cell projection organization
1.17 1.04e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 1.11e-07 GO:0045595 regulation of cell differentiation
1.35 1.11e-07 GO:0051128 regulation of cellular component organization
1.20 1.19e-07 GO:0016070 RNA metabolic process
1.49 1.25e-07 GO:0007010 cytoskeleton organization
1.19 2.11e-07 GO:0010467 gene expression
1.34 2.16e-07 GO:0051649 establishment of localization in cell
1.46 2.28e-07 GO:0032989 cellular component morphogenesis
1.66 2.53e-07 GO:0030029 actin filament-based process
1.31 3.07e-07 GO:0008104 protein localization
1.34 6.26e-07 GO:0016310 phosphorylation
1.29 1.10e-06 GO:0010646 regulation of cell communication
1.61 1.28e-06 GO:0048812 neuron projection morphogenesis
1.46 1.51e-06 GO:0000902 cell morphogenesis
1.30 1.58e-06 GO:0043067 regulation of programmed cell death
1.30 2.56e-06 GO:0042981 regulation of apoptosis
1.22 2.57e-06 GO:0048513 organ development
1.34 4.79e-06 GO:0051049 regulation of transport
1.46 6.86e-06 GO:0044057 regulation of system process
1.62 1.03e-05 GO:0030036 actin cytoskeleton organization
1.31 1.04e-05 GO:2000026 regulation of multicellular organismal development
1.52 1.16e-05 GO:0032990 cell part morphogenesis
1.59 1.23e-05 GO:0051056 regulation of small GTPase mediated signal transduction
1.16 1.58e-05 GO:0090304 nucleic acid metabolic process
1.51 1.86e-05 GO:0048858 cell projection morphogenesis
1.34 1.93e-05 GO:0006468 protein phosphorylation
1.77 2.08e-05 GO:0010959 regulation of metal ion transport
1.32 2.85e-05 GO:0015031 protein transport
1.21 2.86e-05 GO:0044281 small molecule metabolic process
1.23 3.68e-05 GO:0009893 positive regulation of metabolic process
3.21 4.10e-05 GO:0061383 trabecula morphogenesis
1.36 4.54e-05 GO:0046907 intracellular transport
1.31 4.62e-05 GO:0045184 establishment of protein localization
1.50 4.88e-05 GO:0000904 cell morphogenesis involved in differentiation
1.63 5.95e-05 GO:0043269 regulation of ion transport
1.29 7.03e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.29 8.98e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30 9.16e-05 GO:0007049 cell cycle
1.27 1.06e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.27 1.20e-04 GO:0009891 positive regulation of biosynthetic process
1.28 1.26e-04 GO:0042592 homeostatic process
3.21 1.32e-04 GO:0060343 trabecula formation
1.28 1.43e-04 GO:0022607 cellular component assembly
1.30 1.69e-04 GO:0044093 positive regulation of molecular function
1.23 1.91e-04 GO:0009056 catabolic process
1.37 2.21e-04 GO:0009792 embryo development ending in birth or egg hatching
1.23 2.24e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.30 2.46e-04 GO:0051254 positive regulation of RNA metabolic process
1.57 2.56e-04 GO:0046578 regulation of Ras protein signal transduction
1.27 3.37e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.29 3.95e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.22 4.23e-04 GO:0031325 positive regulation of cellular metabolic process
1.52 4.66e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.36 4.67e-04 GO:0043009 chordate embryonic development
1.44 5.23e-04 GO:0007420 brain development
1.40 5.37e-04 GO:0060284 regulation of cell development
1.28 5.86e-04 GO:0010628 positive regulation of gene expression
1.24 6.11e-04 GO:0009892 negative regulation of metabolic process
1.39 6.88e-04 GO:0009719 response to endogenous stimulus
1.37 7.32e-04 GO:0071310 cellular response to organic substance
1.28 8.46e-04 GO:0006811 ion transport
1.76 8.65e-04 GO:0051924 regulation of calcium ion transport
1.35 8.93e-04 GO:0010942 positive regulation of cell death
1.72 9.18e-04 GO:0003012 muscle system process
1.25 9.79e-04 GO:0032268 regulation of cellular protein metabolic process
1.66 1.01e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.66 1.01e-03 GO:0022604 regulation of cell morphogenesis
2.87 1.09e-03 GO:0071356 cellular response to tumor necrosis factor
1.77 1.17e-03 GO:0006936 muscle contraction
1.25 1.22e-03 GO:0031324 negative regulation of cellular metabolic process
1.39 1.54e-03 GO:0045597 positive regulation of cell differentiation
1.52 1.73e-03 GO:0007409 axonogenesis
1.37 1.83e-03 GO:0007417 central nervous system development
1.34 1.90e-03 GO:0072358 cardiovascular system development
1.34 1.90e-03 GO:0072359 circulatory system development
1.24 2.02e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.45 2.12e-03 GO:0012502 induction of programmed cell death
1.37 2.27e-03 GO:0040008 regulation of growth
1.23 2.39e-03 GO:0051246 regulation of protein metabolic process
1.34 2.41e-03 GO:0043068 positive regulation of programmed cell death
1.48 2.42e-03 GO:0061061 muscle structure development
1.41 3.06e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.45 3.12e-03 GO:0006917 induction of apoptosis
1.34 3.16e-03 GO:0043065 positive regulation of apoptosis
1.27 3.35e-03 GO:0031399 regulation of protein modification process
1.30 4.34e-03 GO:0009887 organ morphogenesis
1.32 5.16e-03 GO:0019725 cellular homeostasis
1.29 5.63e-03 GO:0043085 positive regulation of catalytic activity
1.33 5.73e-03 GO:0030001 metal ion transport
1.40 5.83e-03 GO:0051130 positive regulation of cellular component organization
1.23 6.04e-03 GO:0044085 cellular component biogenesis
1.45 6.47e-03 GO:0032446 protein modification by small protein conjugation
1.48 6.53e-03 GO:0016567 protein ubiquitination
1.30 6.64e-03 GO:0006812 cation transport
1.32 6.69e-03 GO:0051094 positive regulation of developmental process
1.29 6.94e-03 GO:0048878 chemical homeostasis
1.26 8.23e-03 GO:0048584 positive regulation of response to stimulus
1.25 9.18e-03 GO:0009790 embryo development
1.43 9.73e-03 GO:0018193 peptidyl-amino acid modification
1.58 1.08e-02 GO:0019216 regulation of lipid metabolic process
1.24 1.11e-02 GO:0009888 tissue development
1.34 1.14e-02 GO:0006461 protein complex assembly
1.55 1.19e-02 GO:0042391 regulation of membrane potential
1.33 1.22e-02 GO:0071822 protein complex subunit organization
1.34 1.25e-02 GO:0060341 regulation of cellular localization
1.40 1.25e-02 GO:0070647 protein modification by small protein conjugation or removal
1.28 1.29e-02 GO:0019220 regulation of phosphate metabolic process
1.28 1.29e-02 GO:0051174 regulation of phosphorus metabolic process
1.28 1.42e-02 GO:0070887 cellular response to chemical stimulus
1.48 1.45e-02 GO:0071495 cellular response to endogenous stimulus
1.49 1.53e-02 GO:0051969 regulation of transmission of nerve impulse
1.31 1.54e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.33 1.61e-02 GO:0070271 protein complex biogenesis
1.94 2.19e-02 GO:0032412 regulation of ion transmembrane transporter activity
1.48 2.31e-02 GO:0044087 regulation of cellular component biogenesis
1.28 2.54e-02 GO:0022402 cell cycle process
1.46 2.69e-02 GO:0031644 regulation of neurological system process
1.41 2.96e-02 GO:0045664 regulation of neuron differentiation
1.22 2.99e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.54 3.01e-02 GO:0060537 muscle tissue development
1.35 3.30e-02 GO:0051960 regulation of nervous system development
1.45 3.42e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.51 3.52e-02 GO:0072511 divalent inorganic cation transport
1.35 3.61e-02 GO:0009725 response to hormone stimulus
1.65 3.79e-02 GO:0051146 striated muscle cell differentiation
1.48 3.91e-02 GO:0032870 cellular response to hormone stimulus
1.34 4.05e-02 GO:0043549 regulation of kinase activity
1.27 4.10e-02 GO:0042325 regulation of phosphorylation
1.41 4.60e-02 GO:0033674 positive regulation of kinase activity
1.20 4.75e-02 GO:0044248 cellular catabolic process
2.04 4.76e-02 GO:0051149 positive regulation of muscle cell differentiation
1.37 4.85e-02 GO:0051270 regulation of cellular component movement

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.21 2.69e-98 GO:0005622 intracellular
1.22 4.68e-95 GO:0044424 intracellular part
1.26 7.15e-80 GO:0005737 cytoplasm
1.22 1.90e-69 GO:0043229 intracellular organelle
1.21 5.49e-69 GO:0043226 organelle
1.21 1.29e-55 GO:0043231 intracellular membrane-bounded organelle
1.21 1.40e-55 GO:0043227 membrane-bounded organelle
1.24 5.53e-38 GO:0044444 cytoplasmic part
1.25 3.17e-35 GO:0005634 nucleus
1.08 6.57e-34 GO:0005623 cell
1.08 6.57e-34 GO:0044464 cell part
1.24 5.96e-27 GO:0044422 organelle part
1.24 8.15e-26 GO:0044446 intracellular organelle part
1.30 2.50e-24 GO:0043234 protein complex
1.27 3.53e-24 GO:0032991 macromolecular complex
1.61 1.24e-18 GO:0043005 neuron projection
1.62 3.21e-16 GO:0045202 synapse
1.40 2.17e-15 GO:0042995 cell projection
1.34 3.68e-15 GO:0005829 cytosol
1.19 1.36e-14 GO:0071944 cell periphery
1.51 8.87e-14 GO:0030054 cell junction
1.19 3.49e-13 GO:0005886 plasma membrane
1.24 4.92e-13 GO:0043228 non-membrane-bounded organelle
1.24 4.92e-13 GO:0043232 intracellular non-membrane-bounded organelle
1.28 1.11e-12 GO:0044459 plasma membrane part
1.35 1.17e-12 GO:0000267 cell fraction
1.31 2.80e-12 GO:0005856 cytoskeleton
1.62 3.91e-11 GO:0044297 cell body
1.63 1.43e-10 GO:0043025 neuronal cell body
1.36 1.51e-10 GO:0005626 insoluble fraction
1.37 3.18e-10 GO:0005624 membrane fraction
1.35 9.74e-10 GO:0044430 cytoskeletal part
1.59 1.03e-09 GO:0044456 synapse part
1.61 9.84e-09 GO:0030425 dendrite
1.50 1.09e-08 GO:0044463 cell projection part
1.62 4.89e-08 GO:0030424 axon
1.23 5.05e-08 GO:0044428 nuclear part
1.57 8.72e-07 GO:0005874 microtubule
1.32 1.55e-06 GO:0012505 endomembrane system
1.25 3.20e-06 GO:0031090 organelle membrane
1.37 3.58e-06 GO:0015630 microtubule cytoskeleton
1.26 6.91e-06 GO:0005783 endoplasmic reticulum
1.27 1.24e-05 GO:0005794 Golgi apparatus
1.64 2.13e-05 GO:0031252 cell leading edge
1.19 4.11e-05 GO:0070013 intracellular organelle lumen
1.19 4.13e-05 GO:0043233 organelle lumen
1.19 4.33e-05 GO:0031974 membrane-enclosed lumen
1.47 6.83e-05 GO:0048471 perinuclear region of cytoplasm
1.90 1.02e-04 GO:0014069 postsynaptic density
1.20 1.05e-04 GO:0031981 nuclear lumen
1.68 1.86e-04 GO:0019717 synaptosome
1.68 2.56e-04 GO:0033267 axon part
2.75 2.59e-04 GO:0034704 calcium channel complex
1.30 2.67e-04 GO:0031975 envelope
1.19 2.83e-04 GO:0005739 mitochondrion
1.29 5.83e-04 GO:0031967 organelle envelope
1.23 5.91e-04 GO:0005654 nucleoplasm
3.00 6.31e-04 GO:0005891 voltage-gated calcium channel complex
1.44 6.40e-04 GO:0015629 actin cytoskeleton
1.58 1.09e-03 GO:0045211 postsynaptic membrane
1.42 1.17e-03 GO:0044431 Golgi apparatus part
1.52 1.69e-03 GO:0045121 membrane raft
1.84 1.76e-03 GO:0044309 neuron spine
1.55 2.29e-03 GO:0030135 coated vesicle
1.45 5.12e-03 GO:0016323 basolateral plasma membrane
1.80 5.21e-03 GO:0005875 microtubule associated complex
1.80 6.05e-03 GO:0043197 dendritic spine
1.61 6.57e-03 GO:0043292 contractile fiber
1.23 9.29e-03 GO:0031982 vesicle
1.90 1.34e-02 GO:0030018 Z disc
1.49 1.34e-02 GO:0034702 ion channel complex
1.57 1.45e-02 GO:0005912 adherens junction
1.34 1.48e-02 GO:0005625 soluble fraction
1.61 1.49e-02 GO:0030016 myofibril
1.23 1.73e-02 GO:0031410 cytoplasmic vesicle
1.24 2.04e-02 GO:0044451 nucleoplasm part
1.26 2.25e-02 GO:0044429 mitochondrial part
1.52 2.36e-02 GO:0030136 clathrin-coated vesicle
1.70 2.42e-02 GO:0030426 growth cone
1.49 2.81e-02 GO:0000139 Golgi membrane
1.68 3.03e-02 GO:0030427 site of polarized growth
2.01 3.14e-02 GO:0031594 neuromuscular junction
1.50 4.07e-02 GO:0005938 cell cortex
1.66 4.40e-02 GO:0030027 lamellipodium

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.18 2.46e-67 GO:0005488 binding
1.28 1.13e-53 GO:0005515 protein binding
1.29 7.64e-17 GO:0000166 nucleotide binding
1.58 7.18e-15 GO:0008092 cytoskeletal protein binding
1.44 4.31e-14 GO:0019899 enzyme binding
1.15 5.34e-13 GO:0003824 catalytic activity
1.27 1.81e-11 GO:0017076 purine nucleotide binding
1.51 2.22e-11 GO:0019904 protein domain specific binding
1.27 2.28e-11 GO:0032555 purine ribonucleotide binding
1.27 2.63e-11 GO:0032553 ribonucleotide binding
1.27 3.65e-11 GO:0035639 purine ribonucleoside triphosphate binding
1.17 5.79e-10 GO:0043169 cation binding
1.17 1.15e-09 GO:0046872 metal ion binding
1.17 1.38e-09 GO:0043167 ion binding
1.53 3.64e-09 GO:0060589 nucleoside-triphosphatase regulator activity
1.53 9.47e-09 GO:0030695 GTPase regulator activity
1.26 9.86e-09 GO:0030554 adenyl nucleotide binding
1.26 1.23e-08 GO:0032559 adenyl ribonucleotide binding
1.27 1.67e-08 GO:0008270 zinc ion binding
1.35 1.70e-08 GO:0030234 enzyme regulator activity
1.59 1.92e-08 GO:0003779 actin binding
1.24 2.53e-08 GO:0046914 transition metal ion binding
1.26 6.60e-08 GO:0005524 ATP binding
1.34 2.75e-07 GO:0016301 kinase activity
1.31 9.93e-07 GO:0022892 substrate-specific transporter activity
1.30 1.80e-06 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.32 3.40e-06 GO:0022891 substrate-specific transmembrane transporter activity
1.17 3.92e-06 GO:0003676 nucleic acid binding
1.34 6.20e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.27 6.57e-06 GO:0005215 transporter activity
1.30 1.04e-05 GO:0022857 transmembrane transporter activity
1.19 3.88e-05 GO:0016740 transferase activity
1.53 4.13e-05 GO:0005083 small GTPase regulator activity
1.34 6.94e-05 GO:0004672 protein kinase activity
1.47 1.13e-04 GO:0019900 kinase binding
1.66 2.73e-04 GO:0005085 guanyl-nucleotide exchange factor activity
1.30 3.06e-04 GO:0015075 ion transmembrane transporter activity
1.73 3.96e-04 GO:0003774 motor activity
1.38 4.77e-04 GO:0004674 protein serine/threonine kinase activity
1.29 6.93e-04 GO:0016462 pyrophosphatase activity
1.29 7.12e-04 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
2.65 7.28e-04 GO:0005245 voltage-gated calcium channel activity
1.34 8.09e-04 GO:0008324 cation transmembrane transporter activity
1.87 8.26e-04 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.29 8.27e-04 GO:0016817 hydrolase activity, acting on acid anhydrides
1.38 1.37e-03 GO:0022838 substrate-specific channel activity
1.29 1.89e-03 GO:0017111 nucleoside-triphosphatase activity
1.93 2.07e-03 GO:0005089 Rho guanyl-nucleotide exchange factor activity
1.26 2.22e-03 GO:0001071 nucleic acid binding transcription factor activity
1.26 2.22e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.27 2.23e-03 GO:0046983 protein dimerization activity
1.38 2.37e-03 GO:0032403 protein complex binding
1.36 2.83e-03 GO:0015267 channel activity
1.23 2.85e-03 GO:0030528 transcription regulator activity
1.40 2.93e-03 GO:0008047 enzyme activator activity
1.36 3.41e-03 GO:0022803 passive transmembrane transporter activity
1.45 3.50e-03 GO:0019901 protein kinase binding
2.31 3.66e-03 GO:0035254 glutamate receptor binding
1.42 3.81e-03 GO:0022836 gated channel activity
1.36 4.06e-03 GO:0005216 ion channel activity
1.16 4.48e-03 GO:0003677 DNA binding
1.65 7.40e-03 GO:0015631 tubulin binding
1.26 8.14e-03 GO:0043565 sequence-specific DNA binding
1.24 1.00e-02 GO:0042802 identical protein binding
1.13 1.13e-02 GO:0016787 hydrolase activity
1.42 1.17e-02 GO:0005261 cation channel activity
1.59 2.07e-02 GO:0005516 calmodulin binding
1.39 2.08e-02 GO:0046982 protein heterodimerization activity
1.36 2.53e-02 GO:0008134 transcription factor binding
1.59 3.97e-02 GO:0017124 SH3 domain binding