• All motifs sorted by activity significance
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• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: PAX4.p2

Z-value: 1.229

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_-_9014351	18.464		Cybb	cytochrome b-245, beta polypeptide
chr5_+_67067477	15.329		Uchl1	ubiquitin carboxy-terminal hydrolase L1
chr4_+_102242664	15.226	NM_001177980	Pde4b	phosphodiesterase 4B, cAMP specific
chr5_+_67067497	15.200		Uchl1	ubiquitin carboxy-terminal hydrolase L1
chr16_-_36666078	14.956	NM_019388	Cd86	CD86 antigen
chr5_+_67067359	14.623	NM_011670	Uchl1	ubiquitin carboxy-terminal hydrolase L1
chr11_-_83343962	10.798	NM_013653	Ccl5	chemokine (C-C motif) ligand 5
chr12_+_118896501	10.267		Rapgef5	Rap guanine nucleotide exchange factor (GEF) 5
chr1_+_90031368	9.809	NM_145079	Ugt1a6a	UDP glucuronosyltransferase 1 family, polypeptide A6A
chr14_-_13655592	9.766	NM_001042617 NM_012061	Cadps	Ca2+-dependent secretion activator
chr14_-_13655558	9.711		Cadps	Ca2+-dependent secretion activator
chr6_+_137359231	9.464	NM_001164402 NM_001164403	Ptpro	protein tyrosine phosphatase, receptor type, O
chr1_+_89999782	9.278	NM_201410	Ugt1a6b	UDP glucuronosyltransferase 1 family, polypeptide A6B
chr5_+_91201521	9.228		Pf4	platelet factor 4
chr5_+_30960594	9.145
chr5_+_91201538	8.854		Pf4	platelet factor 4
chr5_-_92776160	8.841		Cxcl10	chemokine (C-X-C motif) ligand 10
chr6_+_113433507	8.731	NM_133930	Creld1	cysteine-rich with EGF-like domains 1
chr14_-_67422871	8.447		Dpysl2	dihydropyrimidinase-like 2
chr5_+_91201460	8.225	NM_019932	Pf4	platelet factor 4
chr17_+_17539832	8.009		Lix1	limb expression 1 homolog (chicken)
chr6_-_123239765	7.818		Clec4e	C-type lectin domain family 4, member e
chr5_-_5265981	7.767		Cdk14	cyclin-dependent kinase 14
chr5_+_44260035	7.600	NM_007646	Cd38	CD38 antigen
chr15_+_78427476	7.295	NM_028195	Cyth4	cytohesin 4
chr12_-_91976586	7.276	NM_010050	Dio2	deiodinase, iodothyronine, type II
chr6_+_113433408	7.071		Creld1	cysteine-rich with EGF-like domains 1
chr4_-_151822815	7.002		Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr17_+_17539635	6.871	NM_025681	Lix1	limb expression 1 homolog (chicken)
chr19_+_23239333	6.823		Klf9	Kruppel-like factor 9
chr5_+_30960335	6.804		4930471M23Rik	RIKEN cDNA 4930471M23 gene
chr7_-_135137189	6.764		Pycard	PYD and CARD domain containing
chr11_+_31901708	6.715		Nsg2	neuron specific gene family member 2
chr17_-_66121883	6.686	NM_133685	Rab31	RAB31, member RAS oncogene family
chr19_-_11410534	6.391	NM_027836 NM_001025610	Ms4a7	membrane-spanning 4-domains, subfamily A, member 7
chr8_-_74150754	6.283		Unc13a	unc-13 homolog A (C. elegans)
chr6_-_123239886	6.230	NM_019948	Clec4e	C-type lectin domain family 4, member e
chr14_-_20796411	6.090	NM_001038637 NM_010315	Gng2	guanine nucleotide binding protein (G protein), gamma 2
chr14_-_30534966	6.048	NM_009785	Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3
chr5_+_115346942	5.751	NM_011854	Oasl2	2'-5' oligoadenylate synthetase-like 2
chr2_-_156218547	5.721		2900097C17Rik	RIKEN cDNA 2900097C17 gene
chr4_+_130469048	5.699		Laptm5	lysosomal-associated protein transmembrane 5
chr3_+_127492716	5.687	NM_145133	Tifa	TRAF-interacting protein with forkhead-associated domain
chr14_-_103379725	5.615		Kctd12	potassium channel tetramerisation domain containing 12
chr13_+_83803830	5.600		Mef2c	myocyte enhancer factor 2C
chr17_+_43705510	5.410		Pla2g7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr1_-_95518831	5.381		Stk25	serine/threonine kinase 25 (yeast)
chr1_-_36756687	5.369		Actr1b	ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr5_-_137510950	5.330		Ap1s1	adaptor protein complex AP-1, sigma 1
chr7_+_142843598	5.311		Ptpre	protein tyrosine phosphatase, receptor type, E
chr12_+_27154180	5.311		Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr17_+_17539908	5.300		Lix1	limb expression 1 homolog (chicken)
chr10_-_126700105	5.258		Kif5a	kinesin family member 5A
chr2_-_91805686	5.134		Dgkz	diacylglycerol kinase zeta
chr5_-_66410130	5.120		Rbm47	RNA binding motif protein 47
chr17_+_70774131	5.055	NM_027712 NM_177639	Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr6_-_124718354	4.935		Eno2	enolase 2, gamma neuronal
chr17_+_70871444	4.929	NM_001128180	Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr19_+_12535268	4.898	NM_010821	Mpeg1	macrophage expressed gene 1
chr14_-_77436363	4.845	NM_172488	9030625A04Rik	RIKEN cDNA 9030625A04 gene
chr7_-_52622289	4.812		Ppfia3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr6_+_113433656	4.754		Creld1	cysteine-rich with EGF-like domains 1
chr3_-_143868210	4.702	NM_010723	Lmo4	LIM domain only 4
chr7_-_113102453	4.695	NM_001039160 NM_029000	Gvin1	GTPase, very large interferon inducible 1
chr7_-_113358823	4.695	NM_001039160 NM_029000	Gvin1	GTPase, very large interferon inducible 1
chrX_+_50911075	4.687	NM_028375	Cxx1c	CAAX box 1 homolog C (human)
chr7_-_52622167	4.653		Ppfia3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr19_-_11155517	4.634	NM_022430	Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A
chr11_-_99299443	4.609	NM_023256	Krt20	keratin 20
chr12_+_27154043	4.535	NM_020557	Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr17_-_90487479	4.528		Nrxn1	neurexin I
chr4_-_155574875	4.519	NM_015783	Isg15	ISG15 ubiquitin-like modifier
chr2_+_177876710	4.519		Phactr3	phosphatase and actin regulator 3
chrX_-_9046362	4.508	NM_007807	Cybb	cytochrome b-245, beta polypeptide
chrX_-_73120447	4.476		Pls3	plastin 3 (T-isoform)
chr11_-_99105293	4.456	NM_172946	Krt222	keratin 222
chr6_-_3349415	4.447		Samd9l	sterile alpha motif domain containing 9-like
chr1_+_160292470	4.424	NM_007495	Astn1	astrotactin 1
chr10_+_126827366	4.401	NM_001168292	R3hdm2	R3H domain containing 2
chr9_-_75238110	4.330		Mapk6	mitogen-activated protein kinase 6
chr15_-_9459496	4.316		Il7r	interleukin 7 receptor
chr15_-_98593432	4.250		Arf3	ADP-ribosylation factor 3
chr17_+_34442808	4.238	NM_010382	H2-Eb1	histocompatibility 2, class II antigen E beta
chr2_+_177876858	4.216		Phactr3	phosphatase and actin regulator 3
chr7_-_3629631	4.194		Mboat7	membrane bound O-acyltransferase domain containing 7
chrX_-_159081510	4.088	NM_178256	Reps2	RALBP1 associated Eps domain containing protein 2
chr8_-_73132125	4.084	NM_133772	Ssbp4	single stranded DNA binding protein 4
chr12_+_110782654	4.077		Meg3	maternally expressed 3
chr10_-_30375572	4.066	NM_001111267	Ncoa7	nuclear receptor coactivator 7
chr14_-_104243541	4.060		Ednrb	endothelin receptor type B
chr15_-_9459612	4.057	NM_008372	Il7r	interleukin 7 receptor
chr2_+_177876635	3.995	NM_028806	Phactr3	phosphatase and actin regulator 3
chr3_-_90318178	3.968	NM_011309	S100a1	S100 calcium binding protein A1
chrX_-_73120485	3.938	NM_001166453	Pls3	plastin 3 (T-isoform)
chr14_-_71035662	3.901		Epb4.9	erythrocyte protein band 4.9
chr10_+_128236561	3.881		Mmp19	matrix metallopeptidase 19
chr4_-_3501974	3.864		Tmem68	transmembrane protein 68
chr17_+_34442837	3.864		H2-Eb1	histocompatibility 2, class II antigen E beta
chr4_+_130469187	3.855	NM_010686	Laptm5	lysosomal-associated protein transmembrane 5
chr1_-_42751652	3.830		2610017I09Rik	RIKEN cDNA 2610017I09 gene
chr16_-_4879787	3.827	NM_145359	Fam100a	family with sequence similarity 100, member A
chr8_-_46418352	3.817	NM_133969	Cyp4v3	cytochrome P450, family 4, subfamily v, polypeptide 3
chr9_+_59504168	3.813	NM_011099	Pkm2	pyruvate kinase, muscle
chr12_+_110783593	3.785		Meg3	maternally expressed 3
chr5_-_121459496	3.714	NM_011286	Rph3a	rabphilin 3A
chr12_+_32123083	3.684	NM_021353	Slc26a3	solute carrier family 26, member 3
chr6_+_51473868	3.623	NM_001127349	Snx10	sorting nexin 10
chr14_-_20796255	3.618		Gng2	guanine nucleotide binding protein (G protein), gamma 2
chr10_+_80720251	3.615	NM_010768	Matk	megakaryocyte-associated tyrosine kinase
chr2_-_168567422	3.597		Atp9a	ATPase, class II, type 9A
chr7_+_149646740	3.584	NM_001136071	Lsp1	lymphocyte specific 1
chr10_+_80720191	3.577		Matk	megakaryocyte-associated tyrosine kinase
chr6_+_141472906	3.568	NM_001177772 NM_021471	Slco1c1	solute carrier organic anion transporter family, member 1c1
chr7_+_5035137	3.537		Epn1	epsin 1
chr6_-_135664978	3.529
chr13_-_64468380	3.503		Ctsl	cathepsin L
chr4_-_154735351	3.472	NM_008860	Prkcz	protein kinase C, zeta
chr14_-_20796199	3.467		Gng2	guanine nucleotide binding protein (G protein), gamma 2
chr8_-_122364230	3.464		Cotl1	coactosin-like 1 (Dictyostelium)
chr10_+_59740430	3.458		Psap	prosaposin
chr13_-_55629845	3.457	NM_013739	Dok3	docking protein 3
chr1_-_133964541	3.416	NM_001114662 NM_172510	Mfsd4	major facilitator superfamily domain containing 4
chr9_+_21903696	3.412	NM_009922	Cnn1	calponin 1
chr1_-_171677653	3.405	NM_009062	Rgs4	regulator of G-protein signaling 4
chr19_+_8913965	3.390		Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr11_-_6420904	3.388		Myo1g	myosin IG
chr9_+_21903702	3.382		Cnn1	calponin 1
chr5_-_139605617	3.381	NM_008923	Prkar1b	protein kinase, cAMP dependent regulatory, type I beta
chr4_+_144483110	3.369		Dhrs3	dehydrogenase/reductase (SDR family) member 3
chr9_+_59504417	3.364		Pkm2	pyruvate kinase, muscle
chr9_-_91260619	3.359	NM_009573	Zic1	zinc finger protein of the cerebellum 1
chr19_+_28909559	3.338	NM_009199	Slc1a1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr5_-_66542161	3.305	NM_178446	Rbm47	RNA binding motif protein 47
chr16_-_14291427	3.302	NM_001161775 NM_013607	Myh11	myosin, heavy polypeptide 11, smooth muscle
chr4_+_45811893	3.284	NM_028270	Aldh1b1	aldehyde dehydrogenase 1 family, member B1
chr16_+_31428882	3.283		Bdh1	3-hydroxybutyrate dehydrogenase, type 1
chr1_-_173582969	3.280	NM_144539	Slamf7	SLAM family member 7
chr5_-_139606339	3.271		Prkar1b	protein kinase, cAMP dependent regulatory, type I beta
chr4_+_126290825	3.240
chr9_+_36640268	3.236		Fez1	fasciculation and elongation protein zeta 1 (zygin I)
chrX_+_138662725	3.232	NM_172782	Nxt2	nuclear transport factor 2-like export factor 2
chr11_+_54128404	3.230	NM_001033599	Acsl6	acyl-CoA synthetase long-chain family member 6
chr6_-_3349470	3.229	NM_010156	Samd9l	sterile alpha motif domain containing 9-like
chr11_-_114851199	3.220	NM_145437	Cd300ld	CD300 molecule-like family member d
chr5_-_38952934	3.204		Wdr1	WD repeat domain 1
chr11_-_6420931	3.201	NM_178440	Myo1g	myosin IG
chr11_+_75401554	3.162	NM_008850	Pitpna	phosphatidylinositol transfer protein, alpha
chr4_-_91066674	3.145	NM_207685	Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr5_-_123183255	3.127		Camkk2	calcium/calmodulin-dependent protein kinase kinase 2, beta
chrM_+_13320	3.125
chr2_-_103104559	3.119		Ehf	ets homologous factor
chr15_-_98593505	3.117	NM_007478	Arf3	ADP-ribosylation factor 3
chr19_+_4100914	3.117		Pitpnm1	phosphatidylinositol transfer protein, membrane-associated 1
chr4_-_21694265	3.104		2610029I01Rik	RIKEN cDNA 2610029I01 gene
chr1_+_89991575	3.101	NM_201642	Ugt1a7c	UDP glucuronosyltransferase 1 family, polypeptide A7C
chr8_-_86217895	3.054		Pkn1	protein kinase N1
chr5_+_115347505	3.016		Oasl2	2'-5' oligoadenylate synthetase-like 2
chr2_+_138104219	3.015	NM_145534	Btbd3	BTB (POZ) domain containing 3
chr2_+_151931424	3.011		Srxn1	sulfiredoxin 1 homolog (S. cerevisiae)
chr13_-_108516475	3.008		Zswim6	zinc finger, SWIM domain containing 6
chr15_+_25901865	2.997		Fam134b	family with sequence similarity 134, member B
chr14_-_104243474	2.993		Ednrb	endothelin receptor type B
chr10_+_75716647	2.980		S100b	S100 protein, beta polypeptide, neural
chr8_+_119983566	2.966		4933407C03Rik	RIKEN cDNA 4933407C03 gene
chr2_-_30952019	2.953	NM_001177650	Fnbp1	formin binding protein 1
chr3_-_95032039	2.950		Mllt11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr8_+_119983664	2.943
chr16_+_31428887	2.924		Bdh1	3-hydroxybutyrate dehydrogenase, type 1
chr10_+_80720062	2.910		Matk	megakaryocyte-associated tyrosine kinase
chr4_-_116312481	2.904		Akr1a4	aldo-keto reductase family 1, member A4 (aldehyde reductase)
chr5_+_115347750	2.878		Oasl2	2'-5' oligoadenylate synthetase-like 2
chr1_+_160292665	2.870		Astn1	astrotactin 1
chr10_+_21714491	2.866		Sgk1	serum/glucocorticoid regulated kinase 1
chr19_+_8914035	2.855		Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr9_-_110959315	2.850		Ccrl2	chemokine (C-C motif) receptor-like 2
chr2_+_181415111	2.818		Tcea2	transcription elongation factor A (SII), 2
chr3_+_84668066	2.800	NM_001177774	Fbxw7	F-box and WD-40 domain protein 7
chr17_+_43705388	2.798	NM_013737	Pla2g7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr10_+_106708886	2.798	NM_001033223 NM_001039354	Lin7a	lin-7 homolog A (C. elegans)
chr7_+_28914482	2.789	NM_001164655	9530053A07Rik	RIKEN cDNA 9530053A07 gene
chr12_-_8505780	2.785		Rhob	ras homolog gene family, member B
chr10_+_28931448	2.784	NM_001162537	9330159F19Rik	RIKEN cDNA 9330159F19 gene
chr2_-_171868868	2.779	NM_175631	Cbln4	cerebellin 4 precursor protein
chr15_-_103140868	2.778	NM_030720	Gpr84	G protein-coupled receptor 84
chr19_-_6015125	2.760	NM_007600	Capn1	calpain 1
chr1_+_154654953	2.757	NM_010877	Ncf2	neutrophil cytosolic factor 2
chr2_-_168567436	2.752		Atp9a	ATPase, class II, type 9A
chrX_-_40627962	2.712	NM_011855	Odz1	odd Oz/ten-m homolog 1 (Drosophila)
chr10_+_59740373	2.710	NM_001146120 NM_001146121 NM_001146122 NM_001146123 NM_011179	Psap	prosaposin
chr7_-_29185514	2.703		Samd4b	sterile alpha motif domain containing 4B
chr1_-_65003291	2.687	NM_001039493	Plekhm3	pleckstrin homology domain containing, family M, member 3
chrX_-_149078963	2.686		Shroom2	shroom family member 2
chr6_-_72908018	2.683	NM_001039392	Tmsb10	thymosin, beta 10
chr1_-_83404659	2.681	NM_172430	Sphkap	SPHK1 interactor, AKAP domain containing
chr15_+_33012863	2.673	NM_018755 NM_176073	Pgcp	plasma glutamate carboxypeptidase
chr6_-_130287518	2.670	NM_010648	Klra3	killer cell lectin-like receptor, subfamily A, member 3
chr10_+_21714471	2.663	NM_011361	Sgk1	serum/glucocorticoid regulated kinase 1
chr9_+_37175190	2.661	NM_175189	Hepacam	hepatocyte cell adhesion molecule
chr11_+_92960603	2.613	NM_028296	Car10	carbonic anhydrase 10
chr17_+_26551909	2.581	NM_001081656	Neurl1b	neuralized homolog 1b (Drosophila)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.43	2.37e-05	GO:0051179	localization
1.44	3.79e-04	GO:0051234	establishment of localization
1.43	7.79e-04	GO:0006810	transport
6.95	5.68e-03	GO:0030433	ER-associated protein catabolic process
2.83	8.50e-03	GO:0010975	regulation of neuron projection development
2.40	9.43e-03	GO:0045664	regulation of neuron differentiation
2.64	1.33e-02	GO:0031344	regulation of cell projection organization
1.63	2.40e-02	GO:0032879	regulation of localization
2.17	2.99e-02	GO:0050767	regulation of neurogenesis
2.43	4.01e-02	GO:0051129	negative regulation of cellular component organization

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.37	9.84e-19	GO:0005737	cytoplasm
1.26	7.62e-16	GO:0005622	intracellular
1.25	1.07e-14	GO:0044424	intracellular part
1.45	2.47e-14	GO:0044444	cytoplasmic part
1.13	1.41e-10	GO:0005623	cell
1.13	1.41e-10	GO:0044464	cell part
1.46	1.45e-08	GO:0071944	cell periphery
1.23	3.35e-08	GO:0043229	intracellular organelle
1.23	3.74e-08	GO:0043226	organelle
1.45	6.15e-08	GO:0005886	plasma membrane
1.23	1.01e-06	GO:0043227	membrane-bounded organelle
1.23	1.08e-06	GO:0043231	intracellular membrane-bounded organelle
1.74	1.25e-05	GO:0000267	cell fraction
1.20	1.18e-04	GO:0016020	membrane
1.76	2.99e-04	GO:0005626	insoluble fraction
1.61	1.18e-03	GO:0031090	organelle membrane
1.64	1.28e-03	GO:0042995	cell projection
1.72	1.40e-03	GO:0005624	membrane fraction
1.69	1.54e-03	GO:0005794	Golgi apparatus
1.84	6.44e-03	GO:0043005	neuron projection
1.48	1.08e-02	GO:0005829	cytosol
1.46	1.80e-02	GO:0005739	mitochondrion
1.41	2.41e-02	GO:0044459	plasma membrane part
2.66	4.74e-02	GO:0019717	synaptosome

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.34	4.88e-08	GO:0005515	protein binding
1.17	2.59e-06	GO:0005488	binding