Motif ID: PAX5.p2

Z-value: 1.124


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
Pax5 18507 paired box gene 5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax5chr4_-_44723311-0.145.1e-02Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_159326220 16.148 NM_025932
Syap1
synapse associated protein 1
chrX_+_139115908 9.590 NM_177592
Tmem164
transmembrane protein 164
chr9_+_123387818 8.818 NM_013860
Limd1
LIM domains containing 1
chr17_+_24889931 8.199 NM_001012402
Hs3st6
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr2_+_71624985 8.087 NM_008397
Itga6
integrin alpha 6
chr2_-_26459710 7.902 NM_026212
Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr2_-_169956719 7.079 NM_001033299
Zfp217
zinc finger protein 217
chr3_-_79371600 7.000 NM_001162999
Fnip2
folliculin interacting protein 2
chr2_-_26459777 6.688 Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr7_-_142908061 6.218 NM_001081117
Mki67
antigen identified by monoclonal antibody Ki 67
chr4_-_141640159 6.033 NM_145402
Tmem51
transmembrane protein 51
chr2_+_32731648 5.889 NM_146119
Fam129b
family with sequence similarity 129, member B
chr17_-_74694322 5.839 Memo1
mediator of cell motility 1
chr10_-_7500674 5.702 NM_145418
BC013529
cDNA sequence BC013529
chr4_+_155336386 5.659 NM_026125
Fam132a
family with sequence similarity 132, member A
chr6_+_17231334 5.566 NM_016900
Cav2
caveolin 2
chr4_+_155336456 5.351 Fam132a
family with sequence similarity 132, member A
chr17_-_13185014 5.320 Wtap
Wilms' tumour 1-associating protein
chr2_+_18598644 5.167 NM_007552
Bmi1
Bmi1 polycomb ring finger oncogene
chr4_+_136833403 5.103 NM_009523
Wnt4
wingless-related MMTV integration site 4
chr12_+_33639071 5.089 Sypl
synaptophysin-like protein
chr17_-_74694120 5.077 NM_133771
Memo1
mediator of cell motility 1
chr3_+_21975544 5.028 NM_030732
Tbl1xr1
transducin (beta)-like 1X-linked receptor 1
chr11_-_62462024 5.007 NM_198861
BC046404
cDNA sequence BC046404
chr2_-_160192737 4.837 Mafb
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr2_-_160192799 4.638 NM_010658
Mafb
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr12_+_113917038 4.546 NM_001100460
Zbtb42
zinc finger and BTB domain containing 42
chr13_-_49311308 4.516 NM_026738
1110007C09Rik
RIKEN cDNA 1110007C09 gene
chr18_+_73732352 4.404 NM_001039214
Mex3c
mex3 homolog C (C. elegans)
chr6_-_131338282 4.310 Csda
cold shock domain protein A
chr12_+_33639034 4.308 NM_198710
Sypl
synaptophysin-like protein
chr13_-_49063188 4.198 NM_001033268
Fam120a
family with sequence similarity 120, member A
chr6_-_131338465 4.149 NM_011733
NM_139117
Csda

cold shock domain protein A

chr9_+_66793891 4.065 NM_026467
Rps27l
ribosomal protein S27-like
chr1_+_137662648 4.011 NM_013750
Phlda3
pleckstrin homology-like domain, family A, member 3
chr3_-_84284304 3.913 NM_001033301
Fhdc1
FH2 domain containing 1
chr8_+_94881694 3.863 NM_018826
Irx5
Iroquois related homeobox 5 (Drosophila)
chr9_+_118835589 3.860 NM_133710
Ctdspl
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr11_+_115685365 3.806 NM_145438
Llgl2
lethal giant larvae homolog 2 (Drosophila)
chr16_+_77013880 3.731 NM_013918
Usp25
ubiquitin specific peptidase 25
chr11_-_72225084 3.716 NM_177776
Smtnl2
smoothelin-like 2
chr17_-_13185043 3.711 NM_001113532
NM_001113533
Wtap

Wilms' tumour 1-associating protein

chr5_+_53981893 3.563 Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr4_-_59562054 3.546 NM_144904
NM_178164
Rod1

ROD1 regulator of differentiation 1 (S. pombe)

chr4_+_19969198 3.529 NM_010281
Ggh
gamma-glutamyl hydrolase
chr2_-_143836838 3.528 NM_024281
NM_133626
Rrbp1

ribosome binding protein 1

chr12_+_33638809 3.522 NM_013635
Sypl
synaptophysin-like protein
chr19_+_6276885 3.518 NM_010119
Ehd1
EH-domain containing 1
chr11_+_62462314 3.517 Mmgt2
membrane magnesium transporter 2
chr6_+_17231172 3.502 Cav2
caveolin 2
chr5_+_53132872 3.493 Pi4k2b
phosphatidylinositol 4-kinase type 2 beta
chr18_-_89063572 3.476 NM_018821
Socs6
suppressor of cytokine signaling 6
chr4_+_19969261 3.467 Ggh
gamma-glutamyl hydrolase
chr8_+_94881868 3.464 Irx5
Iroquois related homeobox 5 (Drosophila)
chr19_+_6276685 3.442 Ehd1
EH-domain containing 1
chr17_+_47573557 3.406 NM_145489
AI661453
expressed sequence AI661453
chr11_+_115685417 3.396 Llgl2
lethal giant larvae homolog 2 (Drosophila)
chr13_-_49063376 3.326 Fam120a
family with sequence similarity 120, member A
chr17_+_57388873 3.320 NM_134125
Trip10
thyroid hormone receptor interactor 10
chr1_-_36614888 3.290 Sema4c
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr15_-_93105514 3.267 NM_001033275
Gxylt1
glucoside xylosyltransferase 1
chr12_+_34642676 3.246 Twist1
twist homolog 1 (Drosophila)
chr15_-_73015345 3.244 NM_153178
Eif2c2
eukaryotic translation initiation factor 2C, 2
chr3_+_108926062 3.209 NM_172685
Slc25a24
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24
chr3_+_30754871 3.197 NM_001134385
NM_001134386
NM_027965
Gpr160


G protein-coupled receptor 160


chr1_-_95342168 3.176 Hdlbp
high density lipoprotein (HDL) binding protein
chr7_-_86993011 3.171 Anpep
alanyl (membrane) aminopeptidase
chr7_+_148401731 3.154 NM_025886
Rassf7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr4_-_40800983 3.147 B4galt1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr17_+_29627697 3.139 Pim1
proviral integration site 1
chr5_+_110715337 3.132 NM_011132
Pole
polymerase (DNA directed), epsilon
chr9_+_62686569 3.096 NM_001033175
Cln6
ceroid-lipofuscinosis, neuronal 6
chr11_+_62462273 3.083 Mmgt2
membrane magnesium transporter 2
chr5_+_145875080 3.070 NM_023142
Arpc1b
actin related protein 2/3 complex, subunit 1B
chr18_+_67550365 3.059 NM_026473
Tubb6
tubulin, beta 6
chr3_-_144382959 3.034 NM_019464
Sh3glb1
SH3-domain GRB2-like B1 (endophilin)
chr11_+_62462155 3.022 NM_175002
Mmgt2
membrane magnesium transporter 2
chr7_+_104230260 3.016 NM_001162477
NM_010248
Gab2

growth factor receptor bound protein 2-associated protein 2

chr16_+_16213397 2.996 Pkp2
plakophilin 2
chr12_+_86940285 2.993 NM_030887
Jdp2
Jun dimerization protein 2
chr11_-_100007218 2.986 NM_008471
Krt19
keratin 19
chr19_-_34821529 2.941 NM_172838
Slc16a12
solute carrier family 16 (monocarboxylic acid transporters), member 12
chr15_-_10643806 2.939 Rai14
retinoic acid induced 14
chr8_+_74659107 2.894 NM_001001491
Tpm4
tropomyosin 4
chr16_+_16213434 2.891 NM_026163
Pkp2
plakophilin 2
chr2_+_18598882 2.868 Bmi1
Bmi1 polycomb ring finger oncogene
chr7_+_19679892 2.847 NM_011383
Six5
sine oculis-related homeobox 5 homolog (Drosophila)
chr13_-_85428605 2.841 Rasa1
RAS p21 protein activator 1
chr13_+_72766425 2.840 NM_010574
Irx2
Iroquois related homeobox 2 (Drosophila)
chr8_+_47702617 2.832 Casp3
caspase 3
chr7_-_149763980 2.825 H19
H19 fetal liver mRNA
chr12_+_71926429 2.803 NM_028127
Frmd6
FERM domain containing 6
chr18_-_89063689 2.799 Socs6
suppressor of cytokine signaling 6
chr3_-_127599117 2.791 NM_027482
5730508B09Rik
RIKEN cDNA 5730508B09 gene
chr15_-_83002624 2.785 NM_029787
Cyb5r3
cytochrome b5 reductase 3
chr13_-_47025086 2.782 NM_010617
Kif13a
kinesin family member 13A
chrX_+_139116421 2.780 Tmem164
transmembrane protein 164
chr5_-_25004598 2.776 NM_001081383
Mll3
myeloid/lymphoid or mixed-lineage leukemia 3
chr17_-_71660199 2.763 NM_145158
Emilin2
elastin microfibril interfacer 2
chr8_+_47556503 2.762 Acsl1
acyl-CoA synthetase long-chain family member 1
chr3_+_131227854 2.750 Papss1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr10_-_24431707 2.737 Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr7_+_96552871 2.720 NM_008055
Fzd4
frizzled homolog 4 (Drosophila)
chr14_-_35315715 2.698 NM_009758
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr12_-_58646914 2.695 Foxa1
forkhead box A1
chr14_-_73725576 2.681 NM_009029
Rb1
retinoblastoma 1
chr19_+_5637712 2.678 Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr8_-_35040277 2.673 NM_001042674
NM_001042675
NM_019733
Rbpms


RNA binding protein gene with multiple splicing


chr19_+_5637459 2.666 NM_009045
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr9_-_71959599 2.656 NM_011544
Tcf12
transcription factor 12
chr8_-_35040236 2.656 Rbpms
RNA binding protein gene with multiple splicing
chr17_+_88036128 2.649 Epcam
epithelial cell adhesion molecule
chr16_+_33829715 2.628 NM_001145884
NM_010580
Itgb5

integrin beta 5

chr10_-_117283020 2.578 NM_024457
Rap1b
RAS related protein 1b
chr10_+_95403283 2.563 NM_001001932
Eea1
early endosome antigen 1
chr8_+_47556353 2.561 NM_007981
Acsl1
acyl-CoA synthetase long-chain family member 1
chr18_-_52689185 2.554 Lox
lysyl oxidase
chr17_+_87362612 2.528 Rhoq
ras homolog gene family, member Q
chr8_+_28370796 2.528 NM_007918
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr11_-_5161536 2.527 NM_032396
Kremen1
kringle containing transmembrane protein 1
chr13_-_112599181 2.523 NM_011945
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr19_+_7131325 2.516 Macrod1
MACRO domain containing 1
chr5_+_53981453 2.513 NM_009035
NM_001080927
Rbpj

recombination signal binding protein for immunoglobulin kappa J region

chr12_-_114067537 2.511 NM_028023
Cdca4
cell division cycle associated 4
chr13_+_56711111 2.488 Tgfbi
transforming growth factor, beta induced
chr11_+_78002309 2.483 Rab34
RAB34, member of RAS oncogene family
chr7_-_35841450 2.478 Cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr15_+_95621222 2.468 NM_175344
Ano6
anoctamin 6
chr12_+_8778152 2.466 Sdc1
syndecan 1
chr7_+_96552955 2.460 Fzd4
frizzled homolog 4 (Drosophila)
chr8_-_59966523 2.452 NM_021788
Sap30
sin3 associated polypeptide
chr14_+_31528800 2.438 NM_001166532
Sfmbt1
Scm-like with four mbt domains 1
chr17_+_88035996 2.436 Epcam
epithelial cell adhesion molecule
chr15_+_99421458 2.434 NM_009701
Aqp5
aquaporin 5
chr8_-_8660610 2.427 NM_010111
Efnb2
ephrin B2
chr1_-_13579885 2.426 NM_028173
Tram1
translocating chain-associating membrane protein 1
chr6_-_89312545 2.403 NM_008881
Plxna1
plexin A1
chr10_-_117282901 2.401 Rap1b
RAS related protein 1b
chr9_-_65427840 2.394 NM_153119
Plekho2
pleckstrin homology domain containing, family O member 2
chr14_-_73725546 2.385 Rb1
retinoblastoma 1
chr10_-_58684199 2.376 Sept10
septin 10
chr16_+_14361637 2.372 NM_008576
Abcc1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr2_-_104656852 2.372 NM_001123327
Qser1
glutamine and serine rich 1
chr4_-_55545211 2.369 Klf4
Kruppel-like factor 4 (gut)
chr19_+_5637741 2.355 Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr7_-_96666081 2.352 NM_029614
Prss23
protease, serine, 23
chr6_+_124613114 2.350 NM_145130
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr15_-_35085306 2.347 NM_019635
Stk3
serine/threonine kinase 3 (Ste20, yeast homolog)
chr8_+_47702771 2.343 NM_009810
Casp3
caspase 3
chr4_+_44313865 2.338 Melk
maternal embryonic leucine zipper kinase
chr1_+_59821480 2.336 NM_007561
Bmpr2
bone morphogenic protein receptor, type II (serine/threonine kinase)
chr2_+_146047656 2.334 NM_016889
Insm1
insulinoma-associated 1
chr15_-_10644312 2.328 NM_001166408
Rai14
retinoic acid induced 14
chr17_-_31992708 2.322 NM_010831
Sik1
salt inducible kinase 1
chr4_-_19636000 2.321 NM_177327
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr19_+_37624879 2.319 NM_175353
Exoc6
exocyst complex component 6
chr2_-_26788845 2.304 Surf4
surfeit gene 4
chr6_+_116288073 2.294 March8
membrane-associated ring finger (C3HC4) 8
chr16_-_30388534 2.294 NM_001128094
NM_001128096
Atp13a3

ATPase type 13A3

chr3_+_146162954 2.291 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr10_-_24431855 2.281 NM_008813
Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr11_+_53914425 2.280 NM_001136076
NM_011031
P4ha2

procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide

chr2_+_118752232 2.277 NM_028117
Chst14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr17_-_36169573 2.269 NM_010398
H2-T23
histocompatibility 2, T region locus 23
chr11_+_20443168 2.265 NM_021372
Sertad2
SERTA domain containing 2
chrX_-_35809466 2.265 NM_001017959
NM_010685
Lamp2

lysosomal-associated membrane protein 2

chr12_+_8778201 2.262 NM_011519
Sdc1
syndecan 1
chr4_+_45355039 2.260 Dcaf10
DDB1 and CUL4 associated factor 10
chr1_-_13579802 2.257 Tram1
translocating chain-associating membrane protein 1
chr13_-_49311136 2.254 1110007C09Rik
RIKEN cDNA 1110007C09 gene
chr3_+_131227808 2.251 Papss1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr3_+_30993952 2.240 NM_001039090
NM_011386
Skil

SKI-like

chr6_-_72739189 2.234 Tcf7l1
transcription factor 7-like 1 (T-cell specific, HMG box)
chr10_-_83996632 2.227 NM_175451
Ckap4
cytoskeleton-associated protein 4
chr10_+_77888414 2.225 NM_007793
Cstb
cystatin B
chr1_+_182571464 2.221 NM_001103182
NM_175186
Lin9

lin-9 homolog (C. elegans)

chr7_-_149763600 2.215 H19
H19 fetal liver mRNA
chr3_-_108525202 2.211 NM_029522
Gpsm2
G-protein signalling modulator 2 (AGS3-like, C. elegans)
chr15_+_31154137 2.207 NM_146057
Dap
death-associated protein
chr14_-_55545586 2.205 NM_010112
Efs
embryonal Fyn-associated substrate
chr17_+_29235731 2.204 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr11_+_117670970 2.197 NM_009304
Syngr2
synaptogyrin 2
chr19_+_7131270 2.196 Macrod1
MACRO domain containing 1
chr17_+_15841889 2.183 NM_007690
Chd1
chromodomain helicase DNA binding protein 1
chr7_-_148465004 2.183 NM_011328
Sct
secretin
chr7_-_89137131 2.180 NM_007562
Bnc1
basonuclin 1
chr3_-_27609279 2.175 NM_173182
Fndc3b
fibronectin type III domain containing 3B
chr15_-_73015227 2.172 Eif2c2
eukaryotic translation initiation factor 2C, 2
chr11_+_87912647 2.169 NM_198013
Cuedc1
CUE domain containing 1
chr2_-_9800211 2.168 NM_008091
Gata3
GATA binding protein 3
chr15_-_83002561 2.168 Cyb5r3
cytochrome b5 reductase 3
chr10_+_43298969 2.166 NM_009846
Cd24a
CD24a antigen
chr11_-_106860803 2.163 NM_010655
Kpna2
karyopherin (importin) alpha 2
chr2_+_78709195 2.162 NM_009454
Ube2e3
ubiquitin-conjugating enzyme E2E 3, UBC4/5 homolog (yeast)
chr2_-_60800963 2.155 Rbms1
RNA binding motif, single stranded interacting protein 1
chr12_+_3806955 2.146 NM_007872
Dnmt3a
DNA methyltransferase 3A
chr1_-_182743632 2.141 NM_008210
H3f3a
H3 histone, family 3A
chr6_+_116287992 2.137 March8
membrane-associated ring finger (C3HC4) 8
chr4_+_45354940 2.133 NM_153167
Dcaf10
DDB1 and CUL4 associated factor 10
chr11_-_109472715 2.130 Wipi1
WD repeat domain, phosphoinositide interacting 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.38 1.66e-67 GO:0044237 cellular metabolic process
1.52 3.60e-67 GO:0019222 regulation of metabolic process
1.56 4.12e-67 GO:0031323 regulation of cellular metabolic process
1.56 1.58e-65 GO:0080090 regulation of primary metabolic process
1.36 2.71e-64 GO:0044238 primary metabolic process
1.56 6.00e-63 GO:0060255 regulation of macromolecule metabolic process
1.65 9.42e-63 GO:0010468 regulation of gene expression
1.45 1.38e-62 GO:0044260 cellular macromolecule metabolic process
1.66 1.80e-61 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.64 1.20e-59 GO:0010556 regulation of macromolecule biosynthetic process
1.32 1.28e-59 GO:0008152 metabolic process
1.60 8.28e-57 GO:0009889 regulation of biosynthetic process
1.61 1.03e-56 GO:0031326 regulation of cellular biosynthetic process
1.40 1.60e-56 GO:0043170 macromolecule metabolic process
1.65 2.55e-54 GO:0051252 regulation of RNA metabolic process
1.65 1.40e-53 GO:0006355 regulation of transcription, DNA-dependent
1.58 2.93e-52 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.58 1.38e-51 GO:0051171 regulation of nitrogen compound metabolic process
1.54 4.74e-45 GO:0048518 positive regulation of biological process
1.57 6.51e-45 GO:0048522 positive regulation of cellular process
1.58 9.80e-45 GO:0034645 cellular macromolecule biosynthetic process
1.50 1.05e-44 GO:0044249 cellular biosynthetic process
1.58 4.21e-44 GO:0009059 macromolecule biosynthetic process
1.49 1.56e-43 GO:0009058 biosynthetic process
1.61 2.54e-42 GO:0048523 negative regulation of cellular process
1.47 6.79e-42 GO:0032502 developmental process
1.52 3.02e-40 GO:0048856 anatomical structure development
1.49 4.24e-40 GO:0007275 multicellular organismal development
1.55 1.01e-39 GO:0048731 system development
1.55 1.42e-39 GO:0048519 negative regulation of biological process
1.66 2.03e-39 GO:0048513 organ development
1.48 7.65e-37 GO:0016043 cellular component organization
1.63 1.34e-36 GO:0032774 RNA biosynthetic process
1.88 2.65e-36 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.63 3.29e-36 GO:0006351 transcription, DNA-dependent
1.44 1.63e-35 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 7.98e-35 GO:0071840 cellular component organization or biogenesis
1.40 1.12e-34 GO:0006807 nitrogen compound metabolic process
1.40 1.99e-33 GO:0034641 cellular nitrogen compound metabolic process
1.46 1.47e-32 GO:0090304 nucleic acid metabolic process
1.69 3.45e-32 GO:0009653 anatomical structure morphogenesis
1.47 1.46e-31 GO:0010467 gene expression
1.14 2.09e-31 GO:0009987 cellular process
1.96 2.31e-29 GO:0010629 negative regulation of gene expression
1.63 1.05e-27 GO:0009893 positive regulation of metabolic process
1.47 1.08e-27 GO:0016070 RNA metabolic process
1.49 1.69e-27 GO:0071842 cellular component organization at cellular level
1.65 3.44e-27 GO:0010604 positive regulation of macromolecule metabolic process
1.72 3.65e-27 GO:0009892 negative regulation of metabolic process
1.63 1.90e-26 GO:0031325 positive regulation of cellular metabolic process
1.90 4.46e-26 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.46 8.02e-26 GO:0071841 cellular component organization or biogenesis at cellular level
1.74 1.05e-25 GO:0031324 negative regulation of cellular metabolic process
1.73 1.18e-25 GO:0010605 negative regulation of macromolecule metabolic process
1.46 1.18e-25 GO:0044267 cellular protein metabolic process
1.78 1.94e-25 GO:0009888 tissue development
1.85 2.57e-25 GO:0031327 negative regulation of cellular biosynthetic process
1.94 3.34e-25 GO:0045892 negative regulation of transcription, DNA-dependent
1.80 4.97e-25 GO:0009790 embryo development
1.86 7.84e-25 GO:0010558 negative regulation of macromolecule biosynthetic process
1.82 1.58e-24 GO:0009890 negative regulation of biosynthetic process
1.92 1.85e-24 GO:0051253 negative regulation of RNA metabolic process
1.65 2.55e-24 GO:0009966 regulation of signal transduction
2.27 5.76e-24 GO:0035295 tube development
1.48 1.41e-23 GO:0030154 cell differentiation
1.77 3.88e-23 GO:0010628 positive regulation of gene expression
1.47 5.62e-23 GO:0048869 cellular developmental process
1.67 1.55e-22 GO:0050793 regulation of developmental process
1.52 1.74e-22 GO:0006464 protein modification process
1.73 2.22e-22 GO:0010557 positive regulation of macromolecule biosynthetic process
1.78 3.17e-22 GO:0051254 positive regulation of RNA metabolic process
1.78 6.44e-22 GO:0045893 positive regulation of transcription, DNA-dependent
1.38 6.71e-22 GO:0019538 protein metabolic process
1.82 8.19e-22 GO:0051172 negative regulation of nitrogen compound metabolic process
1.69 8.69e-22 GO:0031328 positive regulation of cellular biosynthetic process
1.68 1.91e-21 GO:0009891 positive regulation of biosynthetic process
1.82 2.13e-21 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49 4.37e-21 GO:0043412 macromolecule modification
1.93 1.74e-20 GO:0072358 cardiovascular system development
1.93 1.74e-20 GO:0072359 circulatory system development
1.69 1.81e-20 GO:0051173 positive regulation of nitrogen compound metabolic process
1.70 1.98e-20 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64 4.87e-20 GO:0010941 regulation of cell death
1.65 1.09e-19 GO:0042981 regulation of apoptosis
1.64 1.12e-19 GO:0043067 regulation of programmed cell death
1.73 3.53e-19 GO:0045595 regulation of cell differentiation
1.91 4.25e-19 GO:0009792 embryo development ending in birth or egg hatching
1.48 5.76e-19 GO:0048583 regulation of response to stimulus
1.91 1.00e-18 GO:0043009 chordate embryonic development
1.64 1.02e-18 GO:0032268 regulation of cellular protein metabolic process
1.99 1.25e-18 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.66 1.30e-18 GO:0042127 regulation of cell proliferation
2.01 1.93e-18 GO:0032583 regulation of gene-specific transcription
1.50 7.14e-18 GO:0006996 organelle organization
1.82 1.03e-17 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.50 1.83e-17 GO:0023051 regulation of signaling
1.98 2.10e-17 GO:0060429 epithelium development
1.85 3.79e-17 GO:0048646 anatomical structure formation involved in morphogenesis
1.91 5.37e-17 GO:0051726 regulation of cell cycle
2.05 1.18e-16 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.53 4.06e-16 GO:0007399 nervous system development
1.75 5.34e-16 GO:0009887 organ morphogenesis
1.30 1.24e-15 GO:0051179 localization
1.96 2.62e-15 GO:0048729 tissue morphogenesis
1.61 2.86e-15 GO:2000026 regulation of multicellular organismal development
1.64 2.92e-15 GO:0007049 cell cycle
2.59 3.40e-15 GO:0060541 respiratory system development
2.23 8.08e-15 GO:0035239 tube morphogenesis
1.54 1.33e-14 GO:0010646 regulation of cell communication
1.14 1.65e-14 GO:0065007 biological regulation
1.54 2.23e-14 GO:0051246 regulation of protein metabolic process
1.15 2.75e-14 GO:0050789 regulation of biological process
2.63 3.11e-14 GO:0030323 respiratory tube development
1.50 3.89e-14 GO:0033036 macromolecule localization
1.99 4.51e-14 GO:0001944 vasculature development
1.15 4.61e-14 GO:0050794 regulation of cellular process
2.64 4.62e-14 GO:0030324 lung development
1.84 1.97e-13 GO:0048598 embryonic morphogenesis
1.58 2.76e-13 GO:0048468 cell development
2.04 3.18e-13 GO:0002009 morphogenesis of an epithelium
1.53 3.85e-13 GO:0006796 phosphate metabolic process
1.53 5.34e-13 GO:0006793 phosphorus metabolic process
1.98 1.10e-12 GO:0001701 in utero embryonic development
1.42 1.12e-12 GO:0065009 regulation of molecular function
2.26 1.26e-11 GO:0060562 epithelial tube morphogenesis
1.56 1.43e-11 GO:0016310 phosphorylation
1.50 1.57e-11 GO:0051641 cellular localization
1.95 1.91e-11 GO:0001568 blood vessel development
1.70 2.15e-11 GO:0051094 positive regulation of developmental process
1.40 3.41e-11 GO:0051239 regulation of multicellular organismal process
1.82 3.60e-11 GO:0009968 negative regulation of signal transduction
1.57 4.13e-11 GO:0031399 regulation of protein modification process
1.95 7.11e-11 GO:0048568 embryonic organ development
1.82 8.24e-11 GO:0007389 pattern specification process
1.59 1.00e-10 GO:0006468 protein phosphorylation
2.13 1.27e-10 GO:0032582 negative regulation of gene-specific transcription
1.72 1.30e-10 GO:0043069 negative regulation of programmed cell death
1.54 1.34e-10 GO:0022008 neurogenesis
1.71 1.59e-10 GO:0009967 positive regulation of signal transduction
1.73 1.64e-10 GO:0043066 negative regulation of apoptosis
1.89 1.67e-10 GO:0045596 negative regulation of cell differentiation
2.06 2.00e-10 GO:0048732 gland development
1.67 2.36e-10 GO:0008284 positive regulation of cell proliferation
1.46 2.73e-10 GO:0035556 intracellular signal transduction
1.43 3.75e-10 GO:0050790 regulation of catalytic activity
1.69 3.80e-10 GO:0060548 negative regulation of cell death
1.47 4.01e-10 GO:0008104 protein localization
1.60 4.02e-10 GO:0042325 regulation of phosphorylation
1.54 4.39e-10 GO:0044093 positive regulation of molecular function
1.54 4.59e-10 GO:0048699 generation of neurons
1.59 4.77e-10 GO:0019220 regulation of phosphate metabolic process
1.59 4.77e-10 GO:0051174 regulation of phosphorus metabolic process
1.75 5.19e-10 GO:0010648 negative regulation of cell communication
1.52 5.59e-10 GO:0051128 regulation of cellular component organization
1.60 7.01e-10 GO:0012501 programmed cell death
1.83 8.95e-10 GO:0051301 cell division
1.27 1.03e-09 GO:0051234 establishment of localization
1.95 1.06e-09 GO:0061061 muscle structure development
1.73 2.06e-09 GO:0023057 negative regulation of signaling
1.96 2.90e-09 GO:0048514 blood vessel morphogenesis
1.89 3.01e-09 GO:0007507 heart development
1.94 3.35e-09 GO:0010608 posttranscriptional regulation of gene expression
1.78 4.37e-09 GO:0007167 enzyme linked receptor protein signaling pathway
1.59 5.07e-09 GO:0046907 intracellular transport
1.58 5.27e-09 GO:0006915 apoptosis
1.60 5.50e-09 GO:0001932 regulation of protein phosphorylation
1.80 5.69e-09 GO:0048534 hemopoietic or lymphoid organ development
1.98 5.76e-09 GO:0043193 positive regulation of gene-specific transcription
1.26 6.38e-09 GO:0006810 transport
1.54 6.44e-09 GO:0016265 death
1.80 7.04e-09 GO:0016568 chromatin modification
1.57 8.73e-09 GO:0043085 positive regulation of catalytic activity
1.74 9.18e-09 GO:0051093 negative regulation of developmental process
1.72 1.14e-08 GO:0043549 regulation of kinase activity
1.54 1.31e-08 GO:0008219 cell death
1.62 1.39e-08 GO:0023056 positive regulation of signaling
1.87 1.46e-08 GO:0001501 skeletal system development
2.25 2.00e-08 GO:0061138 morphogenesis of a branching epithelium
1.71 2.00e-08 GO:0045597 positive regulation of cell differentiation
1.62 2.24e-08 GO:0010942 positive regulation of cell death
2.34 2.63e-08 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.15 2.79e-08 GO:0001763 morphogenesis of a branching structure
1.75 2.86e-08 GO:0002520 immune system development
1.61 3.12e-08 GO:0010647 positive regulation of cell communication
1.47 3.31e-08 GO:0051649 establishment of localization in cell
2.11 3.80e-08 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.62 4.45e-08 GO:0043068 positive regulation of programmed cell death
1.72 4.52e-08 GO:0045859 regulation of protein kinase activity
2.06 4.54e-08 GO:0001525 angiogenesis
1.68 4.54e-08 GO:0051338 regulation of transferase activity
1.62 4.76e-08 GO:0051276 chromosome organization
1.63 6.31e-08 GO:0032989 cellular component morphogenesis
1.62 6.51e-08 GO:0048585 negative regulation of response to stimulus
1.62 7.79e-08 GO:0030030 cell projection organization
2.19 1.02e-07 GO:0006417 regulation of translation
1.48 1.03e-07 GO:0048584 positive regulation of response to stimulus
2.03 1.26e-07 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.62 1.44e-07 GO:0071310 cellular response to organic substance
1.71 1.58e-07 GO:0008285 negative regulation of cell proliferation
1.61 1.66e-07 GO:0043065 positive regulation of apoptosis
2.02 1.75e-07 GO:0007346 regulation of mitotic cell cycle
2.23 2.35e-07 GO:0048754 branching morphogenesis of a tube
1.69 2.64e-07 GO:0006325 chromatin organization
1.63 3.58e-07 GO:0007417 central nervous system development
1.66 3.65e-07 GO:0060284 regulation of cell development
1.67 4.41e-07 GO:0000278 mitotic cell cycle
1.63 4.57e-07 GO:0000902 cell morphogenesis
1.75 4.99e-07 GO:0000904 cell morphogenesis involved in differentiation
1.81 6.02e-07 GO:0003002 regionalization
1.77 6.15e-07 GO:0033043 regulation of organelle organization
2.39 9.60e-07 GO:0022612 gland morphogenesis
1.55 1.20e-06 GO:0030182 neuron differentiation
1.30 1.47e-06 GO:0044281 small molecule metabolic process
1.29 1.57e-06 GO:0065008 regulation of biological quality
1.61 1.72e-06 GO:0051247 positive regulation of protein metabolic process
1.71 1.73e-06 GO:0008283 cell proliferation
1.72 1.75e-06 GO:0051270 regulation of cellular component movement
1.44 1.78e-06 GO:0045184 establishment of protein localization
2.14 2.52e-06 GO:0030111 regulation of Wnt receptor signaling pathway
2.67 3.04e-06 GO:0060070 canonical Wnt receptor signaling pathway
1.61 3.20e-06 GO:0061024 membrane organization
1.62 3.59e-06 GO:0032270 positive regulation of cellular protein metabolic process
1.61 3.84e-06 GO:0009719 response to endogenous stimulus
2.25 4.09e-06 GO:0016331 morphogenesis of embryonic epithelium
1.60 4.36e-06 GO:0016044 cellular membrane organization
1.85 4.65e-06 GO:0071900 regulation of protein serine/threonine kinase activity
1.51 4.70e-06 GO:0022402 cell cycle process
2.02 5.20e-06 GO:0001655 urogenital system development
1.84 6.07e-06 GO:0010564 regulation of cell cycle process
1.91 6.14e-06 GO:0009952 anterior/posterior pattern formation
1.66 6.64e-06 GO:0007243 intracellular protein kinase cascade
1.66 6.64e-06 GO:0023014 signal transduction via phosphorylation event
1.43 7.06e-06 GO:0015031 protein transport
2.29 9.01e-06 GO:0030879 mammary gland development
1.66 9.18e-06 GO:0051130 positive regulation of cellular component organization
1.49 9.22e-06 GO:0040011 locomotion
1.94 9.33e-06 GO:0045165 cell fate commitment
1.95 1.01e-05 GO:0016055 Wnt receptor signaling pathway
1.66 1.04e-05 GO:0007420 brain development
2.37 1.21e-05 GO:0060485 mesenchyme development
2.29 1.36e-05 GO:2000027 regulation of organ morphogenesis
1.48 1.76e-05 GO:0016192 vesicle-mediated transport
1.97 1.87e-05 GO:0008544 epidermis development
2.56 2.58e-05 GO:0001942 hair follicle development
2.56 2.58e-05 GO:0022404 molting cycle process
2.56 2.58e-05 GO:0022405 hair cycle process
1.69 2.61e-05 GO:0030097 hemopoiesis
2.52 2.96e-05 GO:0001892 embryonic placenta development
2.15 3.02e-05 GO:0021915 neural tube development
3.12 3.03e-05 GO:0048286 lung alveolus development
1.60 3.12e-05 GO:0010627 regulation of intracellular protein kinase cascade
1.32 3.40e-05 GO:0009056 catabolic process
2.85 3.48e-05 GO:0061180 mammary gland epithelium development
1.91 3.61e-05 GO:0051493 regulation of cytoskeleton organization
1.64 4.23e-05 GO:0031175 neuron projection development
2.29 4.69e-05 GO:0035148 tube formation
1.56 4.71e-05 GO:0022403 cell cycle phase
1.60 4.79e-05 GO:0009725 response to hormone stimulus
2.48 4.99e-05 GO:0042303 molting cycle
2.48 4.99e-05 GO:0042633 hair cycle
2.06 5.31e-05 GO:0048736 appendage development
2.06 5.31e-05 GO:0060173 limb development
1.55 6.11e-05 GO:0006928 cellular component movement
1.54 6.12e-05 GO:0034613 cellular protein localization
1.60 6.13e-05 GO:0051960 regulation of nervous system development
2.37 6.32e-05 GO:0055123 digestive system development
1.93 7.42e-05 GO:0048705 skeletal system morphogenesis
1.35 7.48e-05 GO:0032879 regulation of localization
1.63 8.00e-05 GO:0003006 developmental process involved in reproduction
1.63 8.00e-05 GO:0040012 regulation of locomotion
1.83 8.94e-05 GO:0048562 embryonic organ morphogenesis
1.62 9.25e-05 GO:0050767 regulation of neurogenesis
1.53 9.96e-05 GO:0070727 cellular macromolecule localization
1.58 1.05e-04 GO:0016477 cell migration
1.90 1.12e-04 GO:0007517 muscle organ development
2.05 1.18e-04 GO:0035107 appendage morphogenesis
2.05 1.18e-04 GO:0035108 limb morphogenesis
1.91 1.33e-04 GO:0045786 negative regulation of cell cycle
1.61 1.44e-04 GO:0031401 positive regulation of protein modification process
2.21 1.65e-04 GO:0045787 positive regulation of cell cycle
2.21 1.65e-04 GO:0060828 regulation of canonical Wnt receptor signaling pathway
1.66 1.66e-04 GO:0018193 peptidyl-amino acid modification
1.54 1.71e-04 GO:0048666 neuron development
1.43 1.79e-04 GO:0070887 cellular response to chemical stimulus
1.65 1.80e-04 GO:0030334 regulation of cell migration
1.59 1.97e-04 GO:0022603 regulation of anatomical structure morphogenesis
2.41 2.05e-04 GO:0045667 regulation of osteoblast differentiation
1.85 2.12e-04 GO:0048608 reproductive structure development
1.67 2.18e-04 GO:0040007 growth
1.33 2.37e-04 GO:0044248 cellular catabolic process
1.69 2.58e-04 GO:0048812 neuron projection morphogenesis
1.74 2.68e-04 GO:0010562 positive regulation of phosphorus metabolic process
1.74 2.68e-04 GO:0045937 positive regulation of phosphate metabolic process
2.05 2.75e-04 GO:0033673 negative regulation of kinase activity
1.80 2.77e-04 GO:0016569 covalent chromatin modification
1.53 2.80e-04 GO:0048870 cell motility
1.53 2.80e-04 GO:0051674 localization of cell
1.56 3.08e-04 GO:0044262 cellular carbohydrate metabolic process
1.60 3.42e-04 GO:0032535 regulation of cellular component size
1.64 3.70e-04 GO:0012502 induction of programmed cell death
1.74 3.77e-04 GO:0071495 cellular response to endogenous stimulus
1.63 3.99e-04 GO:2000145 regulation of cell motility
1.73 4.24e-04 GO:0042327 positive regulation of phosphorylation
1.36 4.38e-04 GO:0022607 cellular component assembly
2.91 4.44e-04 GO:0061035 regulation of cartilage development
1.65 4.92e-04 GO:0007264 small GTPase mediated signal transduction
1.85 5.39e-04 GO:0030855 epithelial cell differentiation
2.28 5.59e-04 GO:0048660 regulation of smooth muscle cell proliferation
1.68 5.63e-04 GO:0051101 regulation of DNA binding
1.60 5.94e-04 GO:0051098 regulation of binding
1.63 6.17e-04 GO:0006917 induction of apoptosis
2.06 6.43e-04 GO:0006469 negative regulation of protein kinase activity
2.63 6.58e-04 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.07 6.77e-04 GO:0030326 embryonic limb morphogenesis
2.07 6.77e-04 GO:0035113 embryonic appendage morphogenesis
1.79 7.00e-04 GO:0051272 positive regulation of cellular component movement
1.78 7.22e-04 GO:0016570 histone modification
1.57 7.31e-04 GO:0007423 sensory organ development
1.54 7.51e-04 GO:0090066 regulation of anatomical structure size
2.38 7.59e-04 GO:0048863 stem cell differentiation
2.20 8.51e-04 GO:0001838 embryonic epithelial tube formation
2.20 8.51e-04 GO:0072175 epithelial tube formation
1.88 8.72e-04 GO:0048589 developmental growth
2.83 8.98e-04 GO:0035567 non-canonical Wnt receptor signaling pathway
1.86 1.04e-03 GO:0042692 muscle cell differentiation
1.59 1.09e-03 GO:0030163 protein catabolic process
2.25 1.29e-03 GO:0048762 mesenchymal cell differentiation
1.40 1.32e-03 GO:0033554 cellular response to stress
2.52 1.34e-03 GO:0061008 hepaticobiliary system development
2.66 1.47e-03 GO:0060443 mammary gland morphogenesis
1.62 1.48e-03 GO:0051347 positive regulation of transferase activity
1.64 1.51e-03 GO:0010740 positive regulation of intracellular protein kinase cascade
2.38 1.74e-03 GO:0001657 ureteric bud development
1.68 1.75e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.63 1.76e-03 GO:0033674 positive regulation of kinase activity
1.46 1.81e-03 GO:0005975 carbohydrate metabolic process
1.57 2.10e-03 GO:0032990 cell part morphogenesis
2.47 2.26e-03 GO:0048864 stem cell development
1.64 2.35e-03 GO:0045860 positive regulation of protein kinase activity
1.98 2.41e-03 GO:0030278 regulation of ossification
1.31 2.56e-03 GO:0044085 cellular component biogenesis
1.77 2.89e-03 GO:0030335 positive regulation of cell migration
1.77 2.89e-03 GO:2000147 positive regulation of cell motility
1.47 2.92e-03 GO:0007010 cytoskeleton organization
1.61 3.11e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.59 3.30e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
2.05 3.34e-03 GO:0048706 embryonic skeletal system development
2.48 3.42e-03 GO:0001889 liver development
1.92 3.49e-03 GO:0051348 negative regulation of transferase activity
1.67 3.80e-03 GO:0000280 nuclear division
1.67 3.80e-03 GO:0007067 mitosis
1.80 3.88e-03 GO:0050678 regulation of epithelial cell proliferation
2.38 4.00e-03 GO:0042476 odontogenesis
2.14 4.19e-03 GO:0030178 negative regulation of Wnt receptor signaling pathway
2.34 4.21e-03 GO:0014020 primary neural tube formation
2.30 4.35e-03 GO:0009798 axis specification
1.68 4.41e-03 GO:0043408 regulation of MAPKKK cascade
2.27 4.43e-03 GO:0048565 digestive tract development
1.66 4.67e-03 GO:0090046 regulation of transcription regulator activity
1.59 4.78e-03 GO:0019941 modification-dependent protein catabolic process
1.65 5.07e-03 GO:0000087 M phase of mitotic cell cycle
1.56 5.11e-03 GO:0048858 cell projection morphogenesis
2.48 5.18e-03 GO:0019827 stem cell maintenance
1.98 5.65e-03 GO:0031346 positive regulation of cell projection organization
1.93 6.06e-03 GO:0072001 renal system development
2.34 6.38e-03 GO:0060606 tube closure
1.94 6.59e-03 GO:0001822 kidney development
1.58 6.84e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.43 7.73e-03 GO:0006259 DNA metabolic process
3.06 7.86e-03 GO:0048538 thymus development
1.56 7.98e-03 GO:0044257 cellular protein catabolic process
2.87 8.10e-03 GO:0060603 mammary gland duct morphogenesis
1.72 8.23e-03 GO:0040017 positive regulation of locomotion
1.92 8.88e-03 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
3.58 9.03e-03 GO:0009950 dorsal/ventral axis specification
2.38 9.22e-03 GO:0000082 G1/S transition of mitotic cell cycle
2.13 9.45e-03 GO:0050657 nucleic acid transport
2.13 9.45e-03 GO:0050658 RNA transport
2.13 9.45e-03 GO:0051236 establishment of RNA localization
1.93 9.67e-03 GO:0043281 regulation of caspase activity
2.15 9.75e-03 GO:0048704 embryonic skeletal system morphogenesis
1.68 9.88e-03 GO:0032870 cellular response to hormone stimulus
1.42 9.91e-03 GO:0009057 macromolecule catabolic process
2.18 9.99e-03 GO:0001841 neural tube formation
2.01 1.03e-02 GO:0007369 gastrulation
1.64 1.09e-02 GO:0007409 axonogenesis
1.80 1.09e-02 GO:0051169 nuclear transport
1.62 1.12e-02 GO:0048285 organelle fission
1.95 1.14e-02 GO:0051325 interphase
1.21 1.15e-02 GO:0042221 response to chemical stimulus
1.83 1.16e-02 GO:0001503 ossification
1.81 1.22e-02 GO:0006913 nucleocytoplasmic transport
1.97 1.23e-02 GO:0046822 regulation of nucleocytoplasmic transport
1.97 1.23e-02 GO:0051329 interphase of mitotic cell cycle
2.06 1.24e-02 GO:0042306 regulation of protein import into nucleus
1.45 1.34e-02 GO:0044265 cellular macromolecule catabolic process
1.81 1.35e-02 GO:0010720 positive regulation of cell development
1.99 1.43e-02 GO:0001890 placenta development
1.63 1.50e-02 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity
2.17 1.51e-02 GO:0071901 negative regulation of protein serine/threonine kinase activity
1.45 1.51e-02 GO:0040008 regulation of growth
2.30 1.52e-02 GO:0001843 neural tube closure
2.01 1.53e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.23 1.55e-02 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
1.70 1.62e-02 GO:0007548 sex differentiation
2.50 1.80e-02 GO:0042475 odontogenesis of dentine-containing tooth
1.63 1.82e-02 GO:0030900 forebrain development
1.59 1.85e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
2.07 1.95e-02 GO:0009953 dorsal/ventral pattern formation
1.84 2.05e-02 GO:0010638 positive regulation of organelle organization
1.72 2.07e-02 GO:0060537 muscle tissue development
1.58 2.07e-02 GO:0008361 regulation of cell size
4.68 2.07e-02 GO:0003170 heart valve development
2.12 2.13e-02 GO:0051147 regulation of muscle cell differentiation
1.38 2.28e-02 GO:0071844 cellular component assembly at cellular level
1.61 2.36e-02 GO:0006897 endocytosis
1.61 2.36e-02 GO:0010324 membrane invagination
1.50 2.37e-02 GO:0009894 regulation of catabolic process
1.85 2.50e-02 GO:0032386 regulation of intracellular transport
2.51 2.73e-02 GO:0001658 branching involved in ureteric bud morphogenesis
2.05 2.76e-02 GO:0006403 RNA localization
1.78 3.19e-02 GO:0043523 regulation of neuron apoptosis
1.55 3.25e-02 GO:0032446 protein modification by small protein conjugation
1.92 3.32e-02 GO:0033157 regulation of intracellular protein transport
1.48 3.48e-02 GO:0000279 M phase
2.19 3.50e-02 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.64 3.51e-02 GO:0001934 positive regulation of protein phosphorylation
1.26 3.51e-02 GO:0010033 response to organic substance
2.60 3.61e-02 GO:0045669 positive regulation of osteoblast differentiation
1.81 3.82e-02 GO:0003007 heart morphogenesis
2.52 4.14e-02 GO:0035272 exocrine system development
1.95 4.27e-02 GO:0035270 endocrine system development
1.32 4.33e-02 GO:0000003 reproduction
2.06 4.36e-02 GO:0043524 negative regulation of neuron apoptosis
2.72 4.49e-02 GO:0045931 positive regulation of mitotic cell cycle
2.10 4.81e-02 GO:0051028 mRNA transport
1.32 4.81e-02 GO:0022414 reproductive process
2.39 4.92e-02 GO:0060675 ureteric bud morphogenesis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.33 1.14e-133 GO:0044424 intracellular part
1.32 6.20e-133 GO:0005622 intracellular
1.34 8.54e-106 GO:0043226 organelle
1.34 5.78e-104 GO:0043229 intracellular organelle
1.37 1.69e-99 GO:0043227 membrane-bounded organelle
1.37 2.13e-98 GO:0043231 intracellular membrane-bounded organelle
1.33 1.68e-75 GO:0005737 cytoplasm
1.45 3.15e-69 GO:0005634 nucleus
1.12 1.01e-47 GO:0005623 cell
1.12 1.01e-47 GO:0044464 cell part
1.33 8.78e-44 GO:0044444 cytoplasmic part
1.37 1.06e-36 GO:0044422 organelle part
1.37 4.43e-36 GO:0044446 intracellular organelle part
1.57 4.93e-31 GO:0044428 nuclear part
1.58 1.42e-30 GO:0031974 membrane-enclosed lumen
1.58 3.29e-30 GO:0043233 organelle lumen
1.58 7.56e-30 GO:0070013 intracellular organelle lumen
1.58 1.58e-25 GO:0031981 nuclear lumen
1.38 2.38e-23 GO:0043234 protein complex
1.65 7.79e-22 GO:0005654 nucleoplasm
1.32 6.23e-20 GO:0032991 macromolecular complex
1.46 8.09e-17 GO:0005829 cytosol
1.67 8.58e-15 GO:0044451 nucleoplasm part
1.29 2.46e-11 GO:0043228 non-membrane-bounded organelle
1.29 2.46e-11 GO:0043232 intracellular non-membrane-bounded organelle
1.34 6.53e-09 GO:0005739 mitochondrion
2.22 9.35e-09 GO:0000775 chromosome, centromeric region
2.21 3.19e-08 GO:0005912 adherens junction
1.75 6.06e-08 GO:0005667 transcription factor complex
2.09 2.96e-07 GO:0070161 anchoring junction
1.94 3.16e-07 GO:0005635 nuclear envelope
1.39 8.80e-07 GO:0005794 Golgi apparatus
1.47 1.46e-06 GO:0031975 envelope
1.47 2.10e-06 GO:0031967 organelle envelope
2.37 2.49e-06 GO:0005924 cell-substrate adherens junction
1.58 2.69e-06 GO:0044427 chromosomal part
1.55 2.96e-06 GO:0005694 chromosome
1.91 3.08e-06 GO:0031252 cell leading edge
1.41 3.16e-06 GO:0012505 endomembrane system
2.37 5.69e-06 GO:0005925 focal adhesion
2.26 9.79e-06 GO:0030055 cell-substrate junction
1.76 1.62e-05 GO:0016323 basolateral plasma membrane
1.33 2.24e-05 GO:0005783 endoplasmic reticulum
1.27 3.05e-05 GO:0005856 cytoskeleton
1.30 4.02e-05 GO:0000267 cell fraction
1.63 6.91e-05 GO:0015629 actin cytoskeleton
2.18 1.14e-04 GO:0000776 kinetochore
1.87 1.56e-04 GO:0005938 cell cortex
1.27 4.11e-04 GO:0031090 organelle membrane
1.38 6.41e-04 GO:0030054 cell junction
1.51 8.38e-04 GO:0005625 soluble fraction
2.55 9.46e-04 GO:0032432 actin filament bundle
1.30 1.82e-03 GO:0005626 insoluble fraction
1.37 3.49e-03 GO:0015630 microtubule cytoskeleton
2.51 3.71e-03 GO:0001725 stress fiber
3.68 5.19e-03 GO:0000932 cytoplasmic mRNA processing body
1.64 6.08e-03 GO:0045121 membrane raft
1.28 7.13e-03 GO:0044430 cytoskeletal part
2.34 1.07e-02 GO:0017053 transcriptional repressor complex
2.34 1.07e-02 GO:0042641 actomyosin
1.88 1.29e-02 GO:0000790 nuclear chromatin
4.68 1.32e-02 GO:0000145 exocyst
2.34 1.63e-02 GO:0005643 nuclear pore
2.08 2.21e-02 GO:0000792 heterochromatin
1.12 2.46e-02 GO:0071944 cell periphery
1.92 2.72e-02 GO:0031965 nuclear membrane
1.91 4.00e-02 GO:0016585 chromatin remodeling complex
1.54 4.49e-02 GO:0000785 chromatin
1.51 4.62e-02 GO:0005911 cell-cell junction
1.87 4.84e-02 GO:0030027 lamellipodium
2.06 4.98e-02 GO:0046930 pore complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.26 1.22e-81 GO:0005488 binding
1.39 4.57e-62 GO:0005515 protein binding
1.46 7.03e-31 GO:0003676 nucleic acid binding
1.54 2.06e-27 GO:0003677 DNA binding
1.75 1.48e-25 GO:0030528 transcription regulator activity
1.78 1.46e-22 GO:0001071 nucleic acid binding transcription factor activity
1.78 1.46e-22 GO:0003700 sequence-specific DNA binding transcription factor activity
1.76 2.47e-18 GO:0043565 sequence-specific DNA binding
1.22 2.02e-17 GO:0003824 catalytic activity
1.41 3.23e-15 GO:0016740 transferase activity
1.27 6.02e-15 GO:0043167 ion binding
1.27 1.39e-14 GO:0043169 cation binding
1.96 3.17e-14 GO:0016563 transcription activator activity
1.26 9.42e-14 GO:0046872 metal ion binding
1.94 5.10e-13 GO:0016564 transcription repressor activity
1.43 5.19e-13 GO:0008270 zinc ion binding
1.52 2.24e-12 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.38 4.11e-12 GO:0046914 transition metal ion binding
1.32 4.84e-12 GO:0000166 nucleotide binding
1.91 7.65e-12 GO:0008134 transcription factor binding
1.67 5.07e-11 GO:0019904 protein domain specific binding
1.51 6.85e-11 GO:0019899 enzyme binding
1.50 1.67e-09 GO:0016301 kinase activity
1.50 1.78e-09 GO:0042802 identical protein binding
1.31 1.81e-08 GO:0032553 ribonucleotide binding
1.30 2.44e-08 GO:0032555 purine ribonucleotide binding
1.30 3.20e-08 GO:0017076 purine nucleotide binding
1.30 3.31e-08 GO:0035639 purine ribonucleoside triphosphate binding
1.96 3.69e-08 GO:0003682 chromatin binding
1.53 4.56e-07 GO:0004672 protein kinase activity
1.47 5.61e-07 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.45 1.72e-06 GO:0046983 protein dimerization activity
1.64 2.04e-06 GO:0032403 protein complex binding
1.77 3.73e-06 GO:0000988 protein binding transcription factor activity
1.78 4.16e-06 GO:0000989 transcription factor binding transcription factor activity
1.77 7.52e-06 GO:0003712 transcription cofactor activity
1.29 9.74e-06 GO:0032559 adenyl ribonucleotide binding
3.56 9.82e-06 GO:0017147 Wnt-protein binding
1.29 1.26e-05 GO:0030554 adenyl nucleotide binding
1.29 2.02e-05 GO:0005524 ATP binding
2.21 2.75e-05 GO:0003714 transcription corepressor activity
1.81 3.06e-05 GO:0010843 promoter binding
1.76 5.91e-05 GO:0000975 regulatory region DNA binding
1.76 5.91e-05 GO:0001067 regulatory region nucleic acid binding
1.76 5.91e-05 GO:0044212 transcription regulatory region DNA binding
1.53 6.75e-05 GO:0004674 protein serine/threonine kinase activity
1.76 1.17e-04 GO:0043566 structure-specific DNA binding
1.73 3.73e-04 GO:0019787 small conjugating protein ligase activity
1.50 4.42e-04 GO:0016874 ligase activity
1.68 4.95e-04 GO:0016881 acid-amino acid ligase activity
3.64 6.18e-04 GO:0042813 Wnt receptor activity
1.36 8.51e-04 GO:0003723 RNA binding
1.61 1.44e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.71 1.84e-03 GO:0004842 ubiquitin-protein ligase activity
1.96 1.94e-03 GO:0019838 growth factor binding
1.54 2.04e-03 GO:0019900 kinase binding
2.38 2.32e-03 GO:0046332 SMAD binding
1.42 3.15e-03 GO:0042803 protein homodimerization activity
1.59 3.40e-03 GO:0019901 protein kinase binding
2.09 5.13e-03 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
2.84 8.69e-03 GO:0016278 lysine N-methyltransferase activity
2.84 8.69e-03 GO:0016279 protein-lysine N-methyltransferase activity
3.68 9.59e-03 GO:0030332 cyclin binding
2.02 9.70e-03 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.38 1.26e-02 GO:0008092 cytoskeletal protein binding
2.88 1.27e-02 GO:0018024 histone-lysine N-methyltransferase activity
2.54 2.39e-02 GO:0042054 histone methyltransferase activity
1.82 3.03e-02 GO:0035091 phosphatidylinositol binding
2.21 3.09e-02 GO:0008276 protein methyltransferase activity
1.71 3.63e-02 GO:0003713 transcription coactivator activity
3.83 3.99e-02 GO:0070411 I-SMAD binding
1.48 4.46e-02 GO:0046982 protein heterodimerization activity