Motif ID: POU3F1..4.p2

Z-value: 1.140


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
Pou3f1 18991 POU domain, class 3, transcription factor 1
Pou3f2 18992 POU domain, class 3, transcription factor 2
Pou3f3 18993 POU domain, class 3, transcription factor 3
Pou3f4 18994 POU domain, class 3, transcription factor 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f3chr1_+_427539700.381.3e-07Click!
Pou3f1chr4_+_1243363070.343.6e-06Click!
Pou3f2chr4_-_22415277-0.231.5e-03Click!
Pou3f4chrX_+_1080097280.092.4e-01Click!


Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_96942124 39.557 NM_001190451
Dcn
decorin
chr6_+_4483741 28.300 Col1a2
collagen, type I, alpha 2
chr10_+_97028409 22.435 Lum
lumican
chr17_+_43526389 21.962 NM_001081178
Gpr116
G protein-coupled receptor 116
chr8_-_42140113 20.876 NM_001005864
Mtus1
mitochondrial tumor suppressor 1
chr1_+_45368443 18.309 Col3a1
collagen, type III, alpha 1
chr6_+_17290478 16.778 Cav1
caveolin 1, caveolae protein
chr10_+_97028456 16.053 Lum
lumican
chr2_+_177927788 15.814 NM_001007154
Phactr3
phosphatase and actin regulator 3
chr2_-_62411970 15.648 NM_007986
Fap
fibroblast activation protein
chrX_+_131252542 15.387 Armcx1
armadillo repeat containing, X-linked 1
chr18_+_38456280 15.355 NM_001164622
NM_020012
Rnf14

ring finger protein 14

chr14_-_104242892 15.287 NM_007904
Ednrb
endothelin receptor type B
chr1_-_172018982 15.033 NM_022563
Ddr2
discoidin domain receptor family, member 2
chr14_-_104243541 14.205 Ednrb
endothelin receptor type B
chr4_-_109959185 13.933 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr8_-_37631772 13.492 Dlc1
deleted in liver cancer 1
chr8_-_37631532 13.435 Dlc1
deleted in liver cancer 1
chr11_+_3414983 12.265 Selm
selenoprotein M
chr10_+_115580947 12.108 Ptprr
protein tyrosine phosphatase, receptor type, R
chr5_-_116858596 11.987


chr17_+_8138441 11.711 NM_025789
Rsph3a
radial spoke 3A homolog (Chlamydomonas)
chr1_+_45390415 11.543 Col3a1
collagen, type III, alpha 1
chr17_-_7152972 11.252 Rsph3a
radial spoke 3A homolog (Chlamydomonas)
chr11_+_3414884 11.069 Selm
selenoprotein M
chr9_+_54452124 11.035


chr1_+_45368382 11.011 NM_009930
Col3a1
collagen, type III, alpha 1
chrX_+_131252456 10.532 NM_001166377
NM_001166378
NM_001166379
NM_001166380
NM_030066
Armcx1




armadillo repeat containing, X-linked 1




chr5_-_104542641 10.283 Sparcl1
SPARC-like 1
chr6_-_60779848 10.179 NM_009221
Snca
synuclein, alpha
chr18_+_38476622 10.103


chr6_-_90611092 10.015 Iqsec1
IQ motif and Sec7 domain 1
chr14_-_52530382 9.934 Ndrg2
N-myc downstream regulated gene 2
chr2_+_20431673 9.724 NM_029895
NM_178059
Etl4

enhancer trap locus 4

chr6_-_137519312 8.936 Eps8
epidermal growth factor receptor pathway substrate 8
chr16_+_34995000 8.904 Mylk
myosin, light polypeptide kinase
chrX_-_92361694 8.607 Arhgef9
CDC42 guanine nucleotide exchange factor (GEF) 9
chr11_+_3414792 8.476 Selm
selenoprotein M
chr7_-_149762919 8.209 H19
H19 fetal liver mRNA
chr17_+_37210011 7.879 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_+_69778280 7.698 NM_001193619
Cldn7
claudin 7
chrX_+_93651684 7.449 NM_001159627
NM_181273
Heph

hephaestin

chr2_+_144425688 7.380 NM_025314
Dtd1
D-tyrosyl-tRNA deacylase 1 homolog (S. cerevisiae)
chr4_-_109959366 7.272 NM_001163399
NM_010488
Elavl4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr7_-_149763600 7.175 H19
H19 fetal liver mRNA
chr6_-_120772683 7.127 NM_007510
Atp6v1e1
ATPase, H+ transporting, lysosomal V1 subunit E1
chr1_-_72258684 7.086 NM_001005423
Mreg
melanoregulin
chr7_-_67242493 7.080 NM_001082961
Snrpn
small nuclear ribonucleoprotein N
chr2_-_79748552 7.063 NM_001009978
NM_001009979
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr2_+_144425632 6.962 Dtd1
D-tyrosyl-tRNA deacylase 1 homolog (S. cerevisiae)
chr2_-_122420914 6.927 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr14_+_76362274 6.719 Kctd4
potassium channel tetramerisation domain containing 4
chr2_-_77541328 6.613 NM_001113399
Zfp385b
zinc finger protein 385B
chr12_+_53800369 6.499 NM_198111
Akap6
A kinase (PRKA) anchor protein 6
chr10_+_56097078 6.429 NM_010288
Gja1
gap junction protein, alpha 1
chr19_-_4877874 6.263 NM_013456
Actn3
actinin alpha 3
chr11_-_7113899 6.200 NM_008343
Igfbp3
insulin-like growth factor binding protein 3
chr13_-_111070225 6.180 Rab3c
RAB3C, member RAS oncogene family
chr1_+_169548381 5.877 NM_001159731
Rxrg
retinoid X receptor gamma
chr6_-_48790453 5.745 Tmem176b
transmembrane protein 176B
chrX_+_130829929 5.439 Tmem35
transmembrane protein 35
chr5_+_90890764 5.312 Alb
albumin
chr11_-_83880574 5.072 Dusp14
dual specificity phosphatase 14
chr1_-_136700174 5.022 Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr8_-_42127242 4.961 NM_001005865
Mtus1
mitochondrial tumor suppressor 1
chr19_+_38598686 4.763 NM_019588
Plce1
phospholipase C, epsilon 1
chr7_+_58877199 4.658 NM_080853
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr16_+_43247396 4.656 NM_019778
NM_181058
Zbtb20

zinc finger and BTB domain containing 20

chr9_-_121404750 4.625 Cck
cholecystokinin
chrX_+_135751704 4.582 NM_001164631
NM_001164632
NM_001164633
Mum1l1


melanoma associated antigen (mutated) 1-like 1


chr13_+_49704471 4.568 Ogn
osteoglycin
chr8_-_42127124 4.409 Mtus1
mitochondrial tumor suppressor 1
chrX_-_92361778 4.246 NM_001033329
Arhgef9
CDC42 guanine nucleotide exchange factor (GEF) 9
chr8_-_25707414 4.086 NM_008324
Ido1
indoleamine 2,3-dioxygenase 1
chr1_+_155500166 3.999 NM_026380
Rgs8
regulator of G-protein signaling 8
chr9_-_101101334 3.986 NM_172144
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr1_-_164796609 3.852 Fmo1
flavin containing monooxygenase 1
chr11_-_87811778 3.805 NM_001168471
Dynll2
dynein light chain LC8-type 2
chr9_+_108382255 3.631 Lamb2
laminin, beta 2
chr3_-_98367865 3.418 NM_001111336
NM_008294
Hsd3b4

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4

chr1_-_164796660 3.388 NM_010231
Fmo1
flavin containing monooxygenase 1
chr5_-_17341534 3.309 Cd36
CD36 antigen
chr5_+_89012537 3.242 Rufy3
RUN and FYVE domain containing 3
chr5_+_14025270 3.183 NM_011348
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr11_-_50745128 3.091 NM_013744
Zfp354b
zinc finger protein 354B
chr1_-_174136809 3.037 Pea15a
phosphoprotein enriched in astrocytes 15A
chr16_-_36784864 2.976 NM_001145899
NM_021301
Slc15a2

solute carrier family 15 (H+/peptide transporter), member 2

chr11_+_58234612 2.924 NM_027239
1810065E05Rik
RIKEN cDNA 1810065E05 gene
chr14_-_88871202 2.917 NM_178685
Pcdh20
protocadherin 20
chr6_-_38787222 2.912 NM_001136065
Hipk2
homeodomain interacting protein kinase 2
chrX_+_130829763 2.879 NM_026239
Tmem35
transmembrane protein 35
chr3_-_98314394 2.861 NM_001111336
NM_008294
Hsd3b4

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4

chr9_+_108382180 2.857 NM_008483
Lamb2
laminin, beta 2
chrX_+_155897136 2.831 Mtap7d2
MAP7 domain containing 2
chr14_+_80400057 2.812 NM_001030294
Olfm4
olfactomedin 4
chr18_+_37501355 2.760 NM_053132
Pcdhb7
protocadherin beta 7
chr8_-_47292863 2.709


chr9_+_121275947 2.641 NM_175114
Trak1
trafficking protein, kinesin binding 1
chr7_-_148008029 2.611 NM_001001180
Zfp941
zinc finger protein 941
chr1_-_141273617 2.536 NM_133239
Crb1
crumbs homolog 1 (Drosophila)
chr11_-_50125157 2.506 Canx
calnexin
chr8_-_110112368 2.491 NM_010817
Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr2_+_65508501 2.491 NM_001099298
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr2_-_136213509 2.459 NM_172858
Pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr11_+_95896239 2.394 Snf8
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr8_-_47292973 2.381 Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr11_-_98590680 2.367 NM_011869
Med24
mediator complex subunit 24
chr3_+_141128527 2.336 NM_009472
Unc5c
unc-5 homolog C (C. elegans)
chr3_+_62142698 2.287 NM_001081295
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr17_+_44090192 2.266 Rcan2
regulator of calcineurin 2
chr6_-_12699189 2.247 NM_001164805
Thsd7a
thrombospondin, type I, domain containing 7A
chr1_+_109319264 2.203 NM_027548
Serpinb7
serine (or cysteine) peptidase inhibitor, clade B, member 7
chr9_+_110854048 2.192 NM_028838
Lrrc2
leucine rich repeat containing 2
chrX_+_160876032 2.156 NM_026853
Asb11
ankyrin repeat and SOCS box-containing 11
chr18_+_37595274 2.156 NM_053137
Pcdhb12
protocadherin beta 12
chr13_-_111070344 2.110 Rab3c
RAB3C, member RAS oncogene family
chr14_+_119379988 2.039 Dnajc3
DnaJ (Hsp40) homolog, subfamily C, member 3
chr5_-_17341512 1.975 Cd36
CD36 antigen
chr1_-_174136874 1.910 NM_011063
Pea15a
phosphoprotein enriched in astrocytes 15A
chr9_-_95745663 1.898 NM_001033210
Pls1
plastin 1 (I-isoform)
chrX_+_146029143 1.886 NM_001037716
Gm10439
predicted gene 10439
chr15_-_102993714 1.862 NM_027885
Smug1
single-strand selective monofunctional uracil DNA glycosylase
chr6_-_137118197 1.791 Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr6_-_137118238 1.786 NM_001164212
NM_001164214
Rerg

RAS-like, estrogen-regulated, growth-inhibitor

chr6_+_38331516 1.739 NM_153600
Ttc26
tetratricopeptide repeat domain 26
chr19_+_44277761 1.729 NM_024450
Scd3
stearoyl-coenzyme A desaturase 3
chr11_+_101192080 1.715 Aoc3
amine oxidase, copper containing 3
chr8_-_125760103 1.707 NM_030176
Spata2L
spermatogenesis associated 2-like
chr11_+_95896221 1.689 NM_033568
Snf8
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr3_+_93123668 1.659 NM_133698
Hrnr
hornerin
chr1_-_18127131 1.647 NM_030033
Crisp4
cysteine-rich secretory protein 4
chr8_+_46593141 1.614 NM_172752
Sorbs2
sorbin and SH3 domain containing 2
chr3_+_55265654 1.588 NM_001111051
NM_001111052
NM_001195539
NM_001195540
Dclk1



doublecortin-like kinase 1



chr9_+_30234620 1.574 Snx19
sorting nexin 19
chr6_-_30193802 1.509 NM_001169577
Ube2h
ubiquitin-conjugating enzyme E2H
chr15_-_99358387 1.500 NM_001038658
NM_028224
Faim2

Fas apoptotic inhibitory molecule 2

chr14_+_60997156 1.497 Fam123a
family with sequence similarity 123, member A
chr11_-_86807135 1.496 Ypel2
yippee-like 2 (Drosophila)
chr12_+_37040755 1.478 NM_025312
Sostdc1
sclerostin domain containing 1
chrX_+_145098146 1.464 NM_001114400
Gm10439
Gm15127
predicted gene 10439
predicted gene 15127
chr2_+_144425704 1.461 Dtd1
D-tyrosyl-tRNA deacylase 1 homolog (S. cerevisiae)
chr18_+_65183342 1.444 Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr10_-_6473873 1.410 NM_001033253
Plekhg1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr10_+_126703317 1.409 NM_001190453
NM_001190454
NM_027151
Dctn2


dynactin 2


chr19_+_11611284 1.402 Ms4a4d
membrane-spanning 4-domains, subfamily A, member 4D
chr6_-_137119016 1.401 NM_181988
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr10_+_79605038 1.378 NM_025313
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr4_-_56754248 1.328 NM_025271
Actl7b
actin-like 7b
chr18_+_65183180 1.318 NM_031881
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr2_+_35159780 1.299 Gsn
gelsolin
chr14_-_70607443 1.293 NM_011366
Sorbs3
sorbin and SH3 domain containing 3
chr17_-_46168654 1.271 Vegfa
vascular endothelial growth factor A
chr19_+_11611327 1.240 NM_025658
Ms4a4d
membrane-spanning 4-domains, subfamily A, member 4D
chr9_-_88987672 1.218 NM_001170884
Trim43b
tripartite motif-containing 43B
chr9_+_56712850 1.207 NM_139001
Cspg4
chondroitin sulfate proteoglycan 4
chr1_+_65973093 1.191 NM_027010
Crygf
crystallin, gamma F
chr5_+_122550987 1.190 NM_010861
Myl2
myosin, light polypeptide 2, regulatory, cardiac, slow
chr15_-_102993757 1.179 Smug1
single-strand selective monofunctional uracil DNA glycosylase
chrX_-_161765324 1.123 Glra2
glycine receptor, alpha 2 subunit
chr9_-_69885894 1.122 NM_028087
Gcnt3
glucosaminyl (N-acetyl) transferase 3, mucin type
chrX_+_144435111 1.102 NM_001099920
Gm15093
predicted gene 15093
chr14_-_21483775 1.095 Synpo2l
synaptopodin 2-like
chr2_+_106533281 1.087 Mpped2
metallophosphoesterase domain containing 2
chr4_+_57907600 1.086 Akap2
A kinase (PRKA) anchor protein 2
chr6_+_146673451 1.067 NM_172734
Stk38l
serine/threonine kinase 38 like
chrX_+_144756676 1.055 NM_001099920
Gm15093
predicted gene 15093
chrX_+_145540098 1.055 NM_001099920
Gm15093
predicted gene 15093
chrX_+_144923491 1.055 NM_001082966
Gm15114
predicted gene 15114
chrX_+_145706919 1.055 NM_001099920
Gm15093
predicted gene 15093
chrX_+_145889719 1.055 NM_001099920
Gm15093
predicted gene 15093
chr19_-_5797749 1.040 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr10_-_4707228 1.039 NM_011702
Vip
vasoactive intestinal polypeptide
chr6_-_129281770 1.037 NM_199034
4922502D21Rik
RIKEN cDNA 4922502D21 gene
chr6_-_52859613 1.034 NM_001168277
Jazf1
JAZF zinc finger 1
chr1_-_160887568 1.021 NM_001085376
Pappa2
pappalysin 2
chr14_+_51627425 1.000 NM_001162863
Rnase10
ribonuclease, RNase A family, 10 (non-active)
chr17_+_44413168 0.995 Clic5
chloride intracellular channel 5
chr7_-_23628623 0.980 NM_001166758
Vmn1r159
vomeronasal 1 receptor 159
chr8_-_46495663 0.962 Tlr3
toll-like receptor 3
chr5_+_107860567 0.953 NM_027599
Lpcat2b
lysophosphatidylcholine acyltransferase 2B
chr7_+_18651277 0.930 NM_001162523
NM_001162524
NM_026087
Ceacam12


carcinoembryonic antigen-related cell adhesion molecule 12


chrX_+_145522857 0.912 NM_001122734
NM_011022
Gm15085
Ott
Gm15107
predicted gene 15085
ovary testis transcribed
predicted gene 15107
chrX_+_145882159 0.901 NM_001122734
NM_011022
Gm15085
Ott
Gm15107
predicted gene 15085
ovary testis transcribed
predicted gene 15107
chr4_+_11685294 0.899 NM_019753
Cdh17
cadherin 17
chr17_+_75404893 0.893 Ltbp1
latent transforming growth factor beta binding protein 1
chrX_+_145532494 0.888 NM_001122734
NM_011022
Gm15085
Ott
Gm15107
predicted gene 15085
ovary testis transcribed
predicted gene 15107
chrX_+_144749072 0.888 NM_001122734
NM_011022
Gm15085
Ott
Gm15107
predicted gene 15085
ovary testis transcribed
predicted gene 15107
chr6_+_89843170 0.880 NM_053227
Vmn1r44
vomeronasal 1 receptor 44
chr7_+_99709652 0.830 NM_001162918
NM_025515
Ccdc90b

coiled-coil domain containing 90B

chr11_-_11362390 0.830 NM_001185153
NM_015785
Zpbp

zona pellucida binding protein

chr15_+_77307476 0.827 NM_177744
Apol10a
apolipoprotein L 10a
chr14_-_73768214 0.822 Itm2b
integral membrane protein 2B
chr18_+_65183497 0.814 Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr10_-_68004607 0.801 NM_028491
1700040L02Rik
RIKEN cDNA 1700040L02 gene
chr11_-_109856977 0.798 NM_013851
Abca8b
ATP-binding cassette, sub-family A (ABC1), member 8b
chr11_-_99105293 0.797 NM_172946
Krt222
keratin 222
chr11_+_77851417 0.796 NM_001040403
NM_008028
Flot2

flotillin 2

chr1_+_177628723 0.794 NM_029453
Wdr64
WD repeat domain 64
chr16_-_44558929 0.769 NM_172506
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr8_-_110112260 0.749 Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.42 2.04e-04 GO:0000267 cell fraction
2.39 4.97e-03 GO:0005626 insoluble fraction
2.41 6.17e-03 GO:0005624 membrane fraction
5.22 1.13e-02 GO:0019717 synaptosome
3.37 4.89e-02 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.96 5.94e-03 GO:0008092 cytoskeletal protein binding