Motif ID: POU5F1.p2

Z-value: 1.586


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
Pou5f1 18999 POU domain, class 5, transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou5f1chr17_+_35642981-0.073.3e-01Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_74150754 42.698 Unc13a
unc-13 homolog A (C. elegans)
chr15_+_91991704 31.967 NM_001159647
Cntn1
contactin 1
chr8_+_56040080 31.091 NM_153581
Gpm6a
glycoprotein m6a
chr3_+_13946371 30.204 NM_001163329
NM_001163330
Ralyl

RALY RNA binding protein-like

chrX_+_162782484 25.949 NM_001177955
NM_001177956
NM_001177957
NM_001177958
NM_001177959
NM_001177960
Gpm6b





glycoprotein m6b





chr9_-_91255831 25.906 Zic1
zinc finger protein of the cerebellum 1
chr2_-_6466116 23.955 Celf2
CUGBP, Elav-like family member 2
chr10_+_34018323 22.868 Tspyl4
TSPY-like 4
chr12_+_91050912 22.140 Nrxn3
neurexin III
chr3_-_80606500 20.796 Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr7_+_129432810 20.003 Prkcb
protein kinase C, beta
chr11_-_69419419 19.659 NM_013415
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr8_+_56040445 19.561 Gpm6a
glycoprotein m6a
chr2_-_73497987 19.108 Chn1
chimerin (chimaerin) 1
chr9_-_29770699 18.996 NM_172290
Ntm
neurotrimin
chr2_-_66278870 18.943 NM_018733
Scn1a
sodium channel, voltage-gated, type I, alpha
chr8_+_56040193 18.466 Gpm6a
glycoprotein m6a
chr8_+_56040553 18.434 Gpm6a
glycoprotein m6a
chr5_+_135526788 18.325


chr11_-_69419330 18.299 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr8_+_56040211 17.967 Gpm6a
glycoprotein m6a
chr6_-_92431385 17.768 NM_001134460
Prickle2
prickle homolog 2 (Drosophila)
chr7_+_129432585 17.357 NM_008855
Prkcb
protein kinase C, beta
chr3_+_34549057 17.223 Sox2
SRY-box containing gene 2
chr7_+_53693190 16.654 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr16_+_7069971 16.651 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_-_73498303 16.266 NM_001166604
NM_175752
Chn1

chimerin (chimaerin) 1

chr10_+_69487700 16.107 Ank3
ankyrin 3, epithelial
chr3_-_80606641 15.570 Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr14_+_76362274 15.434 Kctd4
potassium channel tetramerisation domain containing 4
chr10_-_31410391 15.398 Nkain2
Na+/K+ transporting ATPase interacting 2
chr3_+_67696141 15.207 NM_001113419
NM_177585
Iqcj-schip1
Iqcj
IQ motif containing J-schwannomin interacting protein 1 read-through transcript
IQ motif containing J
chr3_-_80606704 14.897 NM_001039195
NM_001083806
NM_013540
Gria2


glutamate receptor, ionotropic, AMPA2 (alpha 2)


chr1_-_42749940 14.872 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr4_-_136891931 14.799 Cdc42
cell division cycle 42 homolog (S. cerevisiae)
chr9_-_49311823 14.618 Ncam1
neural cell adhesion molecule 1
chr12_-_42212337 14.421 NM_010733
Lrrn3
leucine rich repeat protein 3, neuronal
chr16_+_7069927 14.352 NM_183188
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr14_+_14286471 14.306 NM_001163032
Synpr
synaptoporin
chr3_-_84024766 13.809 NM_030706
Trim2
tripartite motif-containing 2
chr11_+_56825307 13.121 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr4_-_126427788 13.057 Ncdn
neurochondrin
chr9_+_21741435 12.756 BC018242
cDNA sequence BC018242
chr1_+_160292470 12.693 NM_007495
Astn1
astrotactin 1
chr2_+_131763454 12.660 Prnp
prion protein
chr17_-_51878720 12.648 Satb1
special AT-rich sequence binding protein 1
chr4_+_122860705 12.486 NM_174998
Hpcal4
hippocalcin-like 4
chr1_-_171677653 12.382 NM_009062
Rgs4
regulator of G-protein signaling 4
chr11_+_56825192 12.361 NM_001113325
NM_008165
Gria1

glutamate receptor, ionotropic, AMPA1 (alpha 1)

chrX_-_92361694 12.243 Arhgef9
CDC42 guanine nucleotide exchange factor (GEF) 9
chr8_+_73278577 11.933 NM_001166399
NM_009001
Rab3a

RAB3A, member RAS oncogene family

chr11_+_56825258 11.746 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chrX_+_132806184 11.672 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr5_+_130090042 11.347 NM_011846
Mmp17
matrix metallopeptidase 17
chr1_-_170362298 11.268 Pbx1
pre B-cell leukemia transcription factor 1
chr3_+_34548916 11.191 NM_011443
Sox2
SRY-box containing gene 2
chr10_+_84849558 11.170 NM_028709
Btbd11
BTB (POZ) domain containing 11
chr10_-_63552994 11.138 NM_178678
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr8_+_59934719 11.129 NM_009136
Scrg1
scrapie responsive gene 1
chr14_-_80171003 10.947 NM_001042726
NM_021543
Pcdh8

protocadherin 8

chr18_+_69753146 10.878 Tcf4
transcription factor 4
chr18_+_69753035 10.730 Tcf4
transcription factor 4
chr12_-_11443284 10.620 NM_012038
Vsnl1
visinin-like 1
chr1_-_166368439 10.526 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr7_+_107422781 10.498 Pgm2l1
phosphoglucomutase 2-like 1
chr12_+_39506844 10.396 NM_007960
Etv1
ets variant gene 1
chr4_-_109960078 10.341 NM_001038698
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr10_-_36855668 10.300 Marcks
myristoylated alanine rich protein kinase C substrate
chr12_+_53800369 10.278 NM_198111
Akap6
A kinase (PRKA) anchor protein 6
chr6_-_35459327 10.244


chr2_+_28048779 10.154 Olfm1
olfactomedin 1
chr2_+_97307652 10.145 NM_178725
Lrrc4c
leucine rich repeat containing 4C
chr11_-_119903061 10.029 NM_001198787
Aatk
apoptosis-associated tyrosine kinase
chr9_+_104472090 9.891 NM_028719
Cpne4
copine IV
chr16_+_41532938 9.854 Lsamp
limbic system-associated membrane protein
chr3_-_146444377 9.703 NM_001164200
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chrX_-_163645313 9.620 Tmsb4x
thymosin, beta 4, X chromosome
chr16_+_7409879 9.546 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_-_60040448 9.509 Tom1l2
target of myb1-like 2 (chicken)
chr10_+_20760625 9.346 NM_001177776
Ahi1
Abelson helper integration site 1
chr11_+_98603186 9.338 NM_178060
Thra
thyroid hormone receptor alpha
chr18_-_23197156 9.258 NM_001161483
Nol4
nucleolar protein 4
chr8_-_47292863 9.249


chr2_+_65508501 9.232 NM_001099298
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr4_-_151851574 9.167 NM_010598
Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr2_+_71892681 9.156 Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr16_-_28753276 9.154 NM_010199
Fgf12
fibroblast growth factor 12
chr7_-_91520991 9.109 Arnt2
aryl hydrocarbon receptor nuclear translocator 2
chr4_-_151851624 9.067 Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr15_-_98780503 9.010 Tuba1a
tubulin, alpha 1A
chrX_+_156411885 8.906 Sh3kbp1
SH3-domain kinase binding protein 1
chr6_+_141472906 8.903 NM_001177772
NM_021471
Slco1c1

solute carrier organic anion transporter family, member 1c1

chr7_+_94732677 8.873 NM_001081414
NM_001143834
Grm5

glutamate receptor, metabotropic 5

chr11_-_51807636 8.794 5430406J06Rik
RIKEN cDNA 5430406J06 gene
chr11_-_99250663 8.773 NM_010660
Krt10
keratin 10
chr1_-_42724504 8.750 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr11_-_58768012 8.739 NM_206882
Hist3h2bb-ps
histone cluster 3, H2bb, pseudogene
chr2_+_28048511 8.688 Olfm1
olfactomedin 1
chr10_+_4795808 8.674 NM_153399
Syne1
synaptic nuclear envelope 1
chr16_+_17045284 8.658 Mapk1
mitogen-activated protein kinase 1
chr1_-_170362388 8.586 NM_008783
NM_183355
Pbx1

pre B-cell leukemia transcription factor 1

chrX_+_132424640 8.510 Bhlhb9
basic helix-loop-helix domain containing, class B9
chrX_+_7455387 8.471 NM_138606
Pim2
proviral integration site 2
chr5_-_23012407 8.443 Srpk2
serine/arginine-rich protein specific kinase 2
chr17_-_90487479 8.326 Nrxn1
neurexin I
chr5_+_67067477 8.274 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr1_+_155500166 8.233 NM_026380
Rgs8
regulator of G-protein signaling 8
chr14_+_66963139 8.223 NM_019675
Stmn4
stathmin-like 4
chr11_-_97372344 8.133 Srcin1
SRC kinase signaling inhibitor 1
chr3_+_17695743 8.082 6430547I21Rik
RIKEN cDNA 6430547I21 gene
chrX_-_161764912 8.069 NM_183427
Glra2
glycine receptor, alpha 2 subunit
chr11_+_97702093 8.047 NM_001080935
B230217C12Rik
RIKEN cDNA B230217C12 gene
chr18_+_37644674 8.028 NM_053142
Pcdhb17
protocadherin beta 17
chr12_+_118997623 8.007 Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr17_+_70871444 7.951 NM_001128180
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr2_+_28048592 7.950 NM_001038613
NM_001038614
Olfm1

olfactomedin 1

chr19_+_44368578 7.923 Scd2
stearoyl-Coenzyme A desaturase 2
chr2_-_140485267 7.905 Flrt3
fibronectin leucine rich transmembrane protein 3
chr5_+_67067497 7.896 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr9_-_54509453 7.750 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr9_-_54509658 7.719 NM_053178
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr16_-_28753298 7.706 Fgf12
fibroblast growth factor 12
chr11_-_69418965 7.699 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr2_-_52414072 7.682 NM_146123
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr7_+_52965052 7.667 Dbp
D site albumin promoter binding protein
chr19_+_44368588 7.630 Scd2
stearoyl-Coenzyme A desaturase 2
chr8_+_56122680 7.628 Gpm6a
glycoprotein m6a
chr2_-_57905140 7.567 NM_029972
Ermn
ermin, ERM-like protein
chr3_+_75878452 7.565 NM_178673
Fstl5
follistatin-like 5
chr16_+_17045125 7.539 Mapk1
mitogen-activated protein kinase 1
chr3_-_83967952 7.504 Trim2
tripartite motif-containing 2
chr11_+_29618696 7.475 Rtn4
reticulon 4
chr3_-_59066744 7.448 NM_027571
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chrX_+_78315963 7.403 NM_138751
Tmem47
transmembrane protein 47
chrX_+_78316003 7.399 Tmem47
transmembrane protein 47
chr13_+_83803830 7.399 Mef2c
myocyte enhancer factor 2C
chr4_+_55093796 7.384 Zfp462
zinc finger protein 462
chr10_-_126626878 7.376 NM_001166413
NM_028027
Arhgef25

Rho guanine nucleotide exchange factor (GEF) 25

chr19_+_44368576 7.282 Scd2
stearoyl-Coenzyme A desaturase 2
chrX_+_133357268 7.271 NM_011123
Plp1
proteolipid protein (myelin) 1
chr10_+_98486068 7.199 Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr6_+_30756073 7.197 Copg2as2
coatomer protein complex, subunit gamma 2, antisense 2
chr15_-_78034648 7.174 Pvalb
parvalbumin
chr5_+_67067359 7.138 NM_011670
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr10_-_36855292 7.119 Marcks
myristoylated alanine rich protein kinase C substrate
chr9_-_121404799 7.098 NM_031161
Cck
cholecystokinin
chr12_+_101447480 7.045 Calm1
calmodulin 1
chr4_+_154932761 7.036 Gnb1
guanine nucleotide binding protein (G protein), beta 1
chr6_+_110595586 7.015 NM_177328
Grm7
glutamate receptor, metabotropic 7
chr8_-_47292973 7.002 Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr2_+_143371807 6.965 NM_008792
Pcsk2
proprotein convertase subtilisin/kexin type 2
chr3_+_114783882 6.930 NM_153157
Olfm3
olfactomedin 3
chr16_-_84955488 6.853 App
amyloid beta (A4) precursor protein
chr19_+_44368557 6.828 Scd2
stearoyl-Coenzyme A desaturase 2
chr12_-_36768992 6.790 Tspan13
tetraspanin 13
chr16_+_94664089 6.788 Ttc3
tetratricopeptide repeat domain 3
chr7_-_82453216 6.778 NM_001109753
Sv2b
synaptic vesicle glycoprotein 2 b
chr3_-_117063090 6.769 D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr6_+_8899165 6.733 Nxph1
neurexophilin 1
chr6_-_92517359 6.669 NM_001134461
Prickle2
prickle homolog 2 (Drosophila)
chr19_-_8913619 6.601 NM_010316
Gng3
guanine nucleotide binding protein (G protein), gamma 3
chr1_-_174128558 6.555 Pea15a
phosphoprotein enriched in astrocytes 15A
chr9_-_83003967 6.493


chrX_+_97972559 6.487 NM_001177780
Dlg3
discs, large homolog 3 (Drosophila)
chr9_+_47338255 6.438 Cadm1
cell adhesion molecule 1
chr7_+_89319681 6.436 Sh3gl3
SH3-domain GRB2-like 3
chr11_-_106642684 6.428 Ddx5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr2_-_32942666 6.408 NM_178888
Garnl3
GTPase activating RANGAP domain-like 3
chr9_-_121404750 6.376 Cck
cholecystokinin
chr13_-_36826104 6.376 Nrn1
neuritin 1
chr5_+_72091188 6.349 NM_008069
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr18_+_37663917 6.339 NM_053145
Pcdhb20
protocadherin beta 20
chr5_+_34974750 6.336


chr17_-_90436488 6.246 Nrxn1
neurexin I
chr13_+_42775991 6.240 NM_198419
Phactr1
phosphatase and actin regulator 1
chr18_-_14002490 6.231 Zfp521
zinc finger protein 521
chr6_+_8900018 6.178 NM_008751
Nxph1
neurexophilin 1
chr16_-_52268571 6.155 Alcam
activated leukocyte cell adhesion molecule
chr15_-_8660729 6.116 NM_148938
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_13789847 6.112 NM_145066
Gpr85
G protein-coupled receptor 85
chr1_-_72905107 6.095 Igfbp5
insulin-like growth factor binding protein 5
chr17_+_37210011 6.094 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_+_89319717 6.080 NM_017400
Sh3gl3
SH3-domain GRB2-like 3
chr11_+_29618531 6.056 NM_024226
Rtn4
reticulon 4
chr6_+_54222814 6.030 NM_023543
Chn2
chimerin (chimaerin) 2
chr6_-_13785233 6.006 Gpr85
G protein-coupled receptor 85
chr11_+_110260435 5.935 NM_011943
Map2k6
mitogen-activated protein kinase kinase 6
chr6_-_141804691 5.887 NM_030687
Slco1a4
solute carrier organic anion transporter family, member 1a4
chr9_+_47338431 5.882 NM_001025600
NM_018770
NM_207675
NM_207676
Cadm1



cell adhesion molecule 1



chr10_+_98478207 5.866 Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr3_+_64913564 5.840 NM_010597
Kcnab1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr7_-_82453166 5.839 Sv2b
synaptic vesicle glycoprotein 2 b
chr5_+_14514975 5.834 Pclo
piccolo (presynaptic cytomatrix protein)
chr6_-_55631256 5.804 NM_009717
Neurod6
neurogenic differentiation 6
chr14_-_88871202 5.787 NM_178685
Pcdh20
protocadherin 20
chr9_-_52484889 5.765 AI593442
expressed sequence AI593442
chr2_+_97306600 5.723


chr7_+_25292105 5.701 NM_146183
Zfp428
zinc finger protein 428
chr15_+_99543952 5.670 Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr12_-_109241423 5.667 NM_001079883
NM_021399
Bcl11b

B-cell leukemia/lymphoma 11B


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.79 2.29e-06 GO:0048699 generation of neurons
1.54 6.82e-06 GO:0023051 regulation of signaling
1.73 1.30e-05 GO:0022008 neurogenesis
1.36 4.44e-05 GO:0006810 transport
2.01 4.47e-05 GO:0048666 neuron development
1.35 4.57e-05 GO:0051234 establishment of localization
1.42 5.66e-05 GO:0030154 cell differentiation
1.68 7.22e-05 GO:0048468 cell development
2.28 7.32e-05 GO:0007268 synaptic transmission
1.41 7.34e-05 GO:0048869 cellular developmental process
1.56 7.34e-05 GO:0007399 nervous system development
1.91 7.88e-05 GO:0030030 cell projection organization
2.35 1.36e-04 GO:0031644 regulation of neurological system process
2.09 1.44e-04 GO:0019226 transmission of nerve impulse
2.09 1.44e-04 GO:0035637 multicellular organismal signaling
1.85 1.47e-04 GO:0030182 neuron differentiation
2.10 1.60e-04 GO:0031175 neuron projection development
1.30 1.90e-04 GO:0051179 localization
1.56 2.79e-04 GO:0010646 regulation of cell communication
2.22 4.33e-04 GO:0048812 neuron projection morphogenesis
1.29 4.87e-04 GO:0032502 developmental process
2.15 6.55e-04 GO:0045664 regulation of neuron differentiation
2.33 6.94e-04 GO:0051969 regulation of transmission of nerve impulse
1.92 6.99e-04 GO:0007267 cell-cell signaling
2.23 7.50e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.55 7.77e-04 GO:0035556 intracellular signal transduction
2.28 9.62e-04 GO:0007409 axonogenesis
1.69 1.60e-03 GO:0007154 cell communication
1.33 1.76e-03 GO:0048731 system development
2.33 1.92e-03 GO:0050804 regulation of synaptic transmission
1.35 1.92e-03 GO:0071842 cellular component organization at cellular level
1.34 2.24e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.30 2.72e-03 GO:0048856 anatomical structure development
1.88 2.82e-03 GO:0060284 regulation of cell development
1.97 3.14e-03 GO:0050767 regulation of neurogenesis
1.99 4.12e-03 GO:0048858 cell projection morphogenesis
1.28 4.78e-03 GO:0007275 multicellular organismal development
1.28 6.45e-03 GO:0016043 cellular component organization
1.31 7.00e-03 GO:0048519 negative regulation of biological process
1.84 7.06e-03 GO:0044057 regulation of system process
1.96 7.46e-03 GO:0032990 cell part morphogenesis
1.27 1.02e-02 GO:0071840 cellular component organization or biogenesis
1.86 1.02e-02 GO:0051960 regulation of nervous system development
1.29 1.23e-02 GO:0048522 positive regulation of cellular process
1.32 1.52e-02 GO:0048523 negative regulation of cellular process
1.56 1.58e-02 GO:0045595 regulation of cell differentiation
1.77 1.67e-02 GO:0000902 cell morphogenesis
1.73 1.89e-02 GO:0032989 cellular component morphogenesis
1.91 2.26e-02 GO:0000904 cell morphogenesis involved in differentiation
1.27 2.29e-02 GO:0048518 positive regulation of biological process
3.36 2.97e-02 GO:0050808 synapse organization
1.80 3.49e-02 GO:0007610 behavior
1.38 3.55e-02 GO:0051239 regulation of multicellular organismal process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.37 3.73e-13 GO:0045202 synapse
2.21 3.46e-12 GO:0043005 neuron projection
1.38 9.31e-11 GO:0071944 cell periphery
1.37 8.92e-10 GO:0005886 plasma membrane
1.15 2.65e-09 GO:0005622 intracellular
1.15 3.88e-09 GO:0044424 intracellular part
2.37 8.81e-09 GO:0044456 synapse part
3.29 1.09e-08 GO:0019717 synaptosome
1.64 3.41e-07 GO:0042995 cell projection
1.70 4.58e-07 GO:0005626 insoluble fraction
2.35 1.90e-06 GO:0030424 axon
1.69 2.40e-06 GO:0005624 membrane fraction
1.58 2.42e-06 GO:0000267 cell fraction
2.27 2.61e-06 GO:0030425 dendrite
1.17 5.58e-06 GO:0005737 cytoplasm
1.98 1.22e-05 GO:0044463 cell projection part
1.23 2.16e-05 GO:0005634 nucleus
3.40 2.34e-05 GO:0014069 postsynaptic density
5.31 2.64e-05 GO:0044304 main axon
1.13 9.64e-05 GO:0043226 organelle
1.13 1.21e-04 GO:0043229 intracellular organelle
1.44 1.47e-04 GO:0005829 cytosol
1.39 2.09e-04 GO:0044459 plasma membrane part
2.59 6.55e-04 GO:0033267 axon part
1.66 8.38e-04 GO:0030054 cell junction
1.92 8.87e-04 GO:0044297 cell body
1.41 9.99e-04 GO:0005856 cytoskeleton
1.90 2.08e-03 GO:0043025 neuronal cell body
2.27 5.26e-03 GO:0045211 postsynaptic membrane
1.12 5.70e-03 GO:0043227 membrane-bounded organelle
1.48 6.50e-03 GO:0044430 cytoskeletal part
1.12 1.02e-02 GO:0043231 intracellular membrane-bounded organelle
1.22 1.83e-02 GO:0032991 macromolecular complex
2.66 2.60e-02 GO:0030427 site of polarized growth
1.24 2.90e-02 GO:0043234 protein complex
1.05 4.18e-02 GO:0005623 cell
1.05 4.18e-02 GO:0044464 cell part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.35 4.67e-16 GO:0005515 protein binding
1.19 3.15e-15 GO:0005488 binding
1.97 5.62e-07 GO:0019904 protein domain specific binding
1.61 3.21e-03 GO:0015075 ion transmembrane transporter activity
2.69 1.62e-02 GO:0030165 PDZ domain binding
1.51 2.01e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.63 2.50e-02 GO:0008092 cytoskeletal protein binding
1.86 3.04e-02 GO:0022836 gated channel activity
1.70 3.10e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.46 3.71e-02 GO:0022857 transmembrane transporter activity