Motif ID: PRDM1.p3

Z-value: 2.358


Transcription factors associated with PRDM1.p3:

Gene SymbolEntrez IDGene Name
Prdm1 12142 PR domain containing 1, with ZNF domain

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prdm1chr10_-_441784740.394.1e-08Click!


Activity profile for motif PRDM1.p3.

activity profile for motif PRDM1.p3


Sorted Z-values histogram for motif PRDM1.p3

Sorted Z-values for motif PRDM1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM1.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_193007202 75.029 NM_007498
Atf3
activating transcription factor 3
chr9_+_5308846 67.477 NM_007609
Casp4
caspase 4, apoptosis-related cysteine peptidase
chr3_+_142283605 57.587 NM_010260
Gbp2
guanylate binding protein 2
chr19_+_34715368 56.882 NM_008331
Ifit1
interferon-induced protein with tetratricopeptide repeats 1
chr10_+_51210768 56.364 NM_013532
Lilrb4
leukocyte immunoglobulin-like receptor, subfamily B, member 4
chr7_-_52494453 53.344 Cd37
CD37 antigen
chr1_-_193006986 50.941 Atf3
activating transcription factor 3
chr19_+_29446941 49.737 Cd274
CD274 antigen
chr1_-_174520562 47.778 NM_029084
Slamf8
SLAM family member 8
chr6_+_145070255 43.876 NM_008511
Lrmp
lymphoid-restricted membrane protein
chr7_-_52494097 43.043 NM_007645
Cd37
CD37 antigen
chr8_-_84926440 42.169 NM_008357
Il15
interleukin 15
chr13_+_74777303 38.606 NM_030711
Erap1
endoplasmic reticulum aminopeptidase 1
chr2_-_28771940 37.862 NM_019446
NM_001164186
Barhl1

BarH-like 1 (Drosophila)

chr8_-_125075222 37.116 NM_001037298
Fam38a
family with sequence similarity 38, member A
chr3_+_106285556 36.984 Dennd2d
DENN/MADD domain containing 2D
chr6_-_39050297 35.828 Parp12
poly (ADP-ribose) polymerase family, member 12
chr1_-_79668530 35.139 NM_183027
Ap1s3
adaptor-related protein complex AP-1, sigma 3
chr19_-_11124897 32.833 NM_001177351
AW112010
expressed sequence AW112010
chr11_-_70273434 31.790 Cxcl16
chemokine (C-X-C motif) ligand 16
chr17_+_34335139 30.944 NM_010724
Psmb8
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
chr9_-_110959315 30.912 Ccrl2
chemokine (C-C motif) receptor-like 2
chr11_-_70273190 30.189 Cxcl16
chemokine (C-X-C motif) ligand 16
chr11_-_70273453 29.998 NM_023158
Cxcl16
chemokine (C-X-C motif) ligand 16
chr17_-_34324234 29.510 NM_013585
Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr11_-_70273251 29.051 Cxcl16
chemokine (C-X-C motif) ligand 16
chr9_+_38525852 28.948 NM_001145957
NM_172767
Vwa5a

von Willebrand factor A domain containing 5A

chr12_-_27141303 28.945 NM_021384
Rsad2
radical S-adenosyl methionine domain containing 2
chr8_-_84927109 28.652 Il15
interleukin 15
chr11_-_70272909 28.593 Cxcl16
chemokine (C-X-C motif) ligand 16
chr19_-_3905229 28.455 NM_016921
Tcirg1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr17_+_34056555 27.611 Tapbp
TAP binding protein
chr15_-_76073789 27.596 Parp10
poly (ADP-ribose) polymerase family, member 10
chr9_-_106378494 27.282 Parp3
poly (ADP-ribose) polymerase family, member 3
chr9_+_107877887 27.036 NM_023738
Uba7
ubiquitin-like modifier activating enzyme 7
chr5_-_92776027 26.927 Cxcl10
chemokine (C-X-C motif) ligand 10
chr7_-_109713935 26.789 NM_001082552
NM_009277
Trim21

tripartite motif-containing 21

chr13_+_33096472 26.547 Serpinb9
serine (or cysteine) peptidase inhibitor, clade B, member 9
chr17_+_34056585 26.244 Tapbp
TAP binding protein
chr11_-_70273333 25.989 Cxcl16
chemokine (C-X-C motif) ligand 16
chr15_-_76073869 25.953 NM_001163575
NM_001163576
Parp10

poly (ADP-ribose) polymerase family, member 10

chr15_-_76073854 25.623 Parp10
poly (ADP-ribose) polymerase family, member 10
chr10_-_87819740 25.282 Dram1
DNA-damage regulated autophagy modulator 1
chr11_-_106257752 25.160 Ern1
endoplasmic reticulum (ER) to nucleus signalling 1
chr12_-_27141277 24.677 Rsad2
radical S-adenosyl methionine domain containing 2
chr15_-_76073582 23.869 Parp10
poly (ADP-ribose) polymerase family, member 10
chr17_+_34056798 23.758 Tapbp
TAP binding protein
chr8_-_108461909 23.631 Psmb10
proteasome (prosome, macropain) subunit, beta type 10
chr9_-_88626613 23.346 NM_007536
Bcl2a1d
B-cell leukemia/lymphoma 2 related protein A1d
chr2_+_85860710 23.014 NM_146578
Olfr1033
olfactory receptor 1033
chr3_+_106285348 22.748 NM_001093754
Dennd2d
DENN/MADD domain containing 2D
chr9_-_106378901 21.982 NM_145619
Parp3
poly (ADP-ribose) polymerase family, member 3
chr8_-_108462291 21.932 NM_013640
Psmb10
proteasome (prosome, macropain) subunit, beta type 10
chr19_-_20465115 21.819 Anxa1
annexin A1
chr14_+_103446209 21.560 NM_008392
Irg1
immunoresponsive gene 1
chr12_-_27141171 21.334 Rsad2
radical S-adenosyl methionine domain containing 2
chr13_+_33096402 19.488 NM_009256
Serpinb9
serine (or cysteine) peptidase inhibitor, clade B, member 9
chrX_+_104479684 19.475 NM_001177782
Gpr174
G protein-coupled receptor 174
chr19_+_12873115 19.359 Lpxn
leupaxin
chr14_+_57194455 19.192 NM_001145978
Parp4
poly (ADP-ribose) polymerase family, member 4
chr2_-_51828440 18.801 Nmi
N-myc (and STAT) interactor
chr14_-_56209708 18.782 NM_011190
Psme2
Psme2b-ps
proteasome (prosome, macropain) 28 subunit, beta
protease (prosome, macropain) 28 subunit beta B, pseudogene
chr6_-_51962458 18.621 NM_018773
Skap2
src family associated phosphoprotein 2
chr17_+_34056367 17.708 NM_001025313
NM_009318
Tapbp

TAP binding protein

chr17_-_6943173 17.641 Ezr
ezrin
chr12_+_112655640 17.435 NM_028807
1200009I06Rik
RIKEN cDNA 1200009I06 gene
chr11_+_101309725 17.031 NM_027320
Ifi35
interferon-induced protein 35
chr6_+_97879810 16.971 NM_001178049
Mitf
microphthalmia-associated transcription factor
chr16_+_24393435 16.815 NM_178665
Lpp
LIM domain containing preferred translocation partner in lipoma
chr1_+_87546558 16.587 NM_013673
Sp100
nuclear antigen Sp100
chr12_+_33987379 16.583 NM_001033436
Atxn7l1
ataxin 7-like 1
chr10_+_127080013 16.028 NM_009284
Stat6
signal transducer and activator of transcription 6
chr9_+_88851757 16.009 NM_009742
Bcl2a1a
B-cell leukemia/lymphoma 2 related protein A1a
chr14_+_56197282 15.892 NM_011189
Psme1
proteasome (prosome, macropain) 28 subunit, alpha
chr6_+_123212124 15.462 NM_001163161
NM_010819
Clec4d

C-type lectin domain family 4, member d

chr8_+_131028275 14.944 Nrp1
neuropilin 1
chr5_-_92776160 14.155 Cxcl10
chemokine (C-X-C motif) ligand 10
chr10_+_127080251 13.938 Stat6
signal transducer and activator of transcription 6
chr1_-_173164404 13.719 NM_010185
Fcer1g
Fc receptor, IgE, high affinity I, gamma polypeptide
chr16_-_35871459 13.697 NM_001039530
Parp14
poly (ADP-ribose) polymerase family, member 14
chr6_+_39331379 13.143 NM_011226
Rab19
RAB19, member RAS oncogene family
chr7_+_29573987 12.881 NM_177158
Rinl
Ras and Rab interactor-like
chr5_+_150076605 12.303 NM_009663
Alox5ap
arachidonate 5-lipoxygenase activating protein
chr6_+_123212210 12.243 Clec4d
C-type lectin domain family 4, member d
chr1_+_182872588 12.115 NM_144794
Tmem63a
transmembrane protein 63a
chr1_+_6720153 11.564 St18
suppression of tumorigenicity 18
chr7_-_52391419 11.265 Flt3l
FMS-like tyrosine kinase 3 ligand
chr19_-_5845001 11.136 Neat1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr9_-_106378454 11.067 Parp3
poly (ADP-ribose) polymerase family, member 3
chr1_+_6720087 10.757 NM_173868
St18
suppression of tumorigenicity 18
chr9_-_88626434 10.637 Bcl2a1d
B-cell leukemia/lymphoma 2 related protein A1d
chr2_-_119303348 10.515 NM_026574
Ino80
INO80 homolog (S. cerevisiae)
chr13_-_40825789 10.261 NM_001122948
Tcfap2a
transcription factor AP-2, alpha
chr1_+_185858324 10.255 NM_022019
Dusp10
dual specificity phosphatase 10
chr13_-_117814322 9.908 NM_001081009
Parp8
poly (ADP-ribose) polymerase family, member 8
chr7_-_108986589 9.902 NM_010567
Inppl1
inositol polyphosphate phosphatase-like 1
chr17_+_37330836 9.783 NM_023137
Ubd
ubiquitin D
chr6_-_125181731 9.297 NM_145391
Tapbpl
TAP binding protein-like
chr2_-_44965866 9.224 Zeb2
zinc finger E-box binding homeobox 2
chr8_+_47825098 9.033 NM_008391
Irf2
interferon regulatory factor 2
chr7_-_52391756 8.792 NM_013520
Flt3l
FMS-like tyrosine kinase 3 ligand
chr5_+_115347505 8.153 Oasl2
2'-5' oligoadenylate synthetase-like 2
chr19_+_12873063 7.742 NM_134152
Lpxn
leupaxin
chr1_+_183081066 7.691 Cnih4
cornichon homolog 4 (Drosophila)
chr1_+_155596555 7.636 NM_011882
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr8_+_36438761 7.632 NM_177741
Ppp1r3b
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr7_-_109166668 7.557 NM_010531
Il18bp
interleukin 18 binding protein
chr4_-_154010868 7.259 NM_001177995
NM_027504
Prdm16

PR domain containing 16

chr19_+_36484237 7.240 Pcgf5
polycomb group ring finger 5
chr5_+_3343861 7.235 Cdk6
cyclin-dependent kinase 6
chr9_-_110959702 7.234 NM_017466
Ccrl2
chemokine (C-C motif) receptor-like 2
chr2_+_11627013 7.217 NM_133836
Il15ra
interleukin 15 receptor, alpha chain
chr1_-_173579128 7.075 Slamf7
SLAM family member 7
chr8_+_26750755 6.889 NM_001081269
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr6_+_121195885 6.508 NM_011909
Usp18
ubiquitin specific peptidase 18
chr1_+_179372452 6.447 Zfp238
zinc finger protein 238
chr14_+_14845004 6.377 NM_139227
Atxn7
ataxin 7
chr9_+_5298516 6.225 NM_009807
Casp1
caspase 1
chr8_-_85856284 6.147 NM_001170691
NM_178736
Elmod2

ELMO domain containing 2

chr5_+_28492235 6.144 NM_010134
En2
engrailed 2
chr6_-_39068241 6.137 Parp12
poly (ADP-ribose) polymerase family, member 12
chr13_-_3917356 6.118 NM_019671
Net1
neuroepithelial cell transforming gene 1
chr5_-_105668551 5.997 NM_001039646
Gbp10
guanylate-binding protein 10
chr7_-_109166133 5.877 Il18bp
interleukin 18 binding protein
chr2_-_25221101 5.761 NM_001033293
Uap1l1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr15_-_77277889 5.749 NM_001024848
Apol7b
apolipoprotein L 7b
chr10_-_87819765 5.717 NM_027878
Dram1
DNA-damage regulated autophagy modulator 1
chr5_-_105411580 5.701 NM_030239
Abcg3
ATP-binding cassette, sub-family G (WHITE), member 3
chr17_-_35309483 5.659 Aif1
allograft inflammatory factor 1
chr19_-_5845462 5.526 Neat1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr11_+_6460185 5.326 NM_001190344
Ccm2
cerebral cavernous malformation 2 homolog (human)
chr3_-_115710131 5.295 NM_023214
Slc30a7
solute carrier family 30 (zinc transporter), member 7
chr2_+_11627385 5.238 NM_008358
Il15ra
interleukin 15 receptor, alpha chain
chr8_+_95351212 5.113 NM_008610
Mmp2
matrix metallopeptidase 2
chr4_+_15211137 5.109 Tmem64
transmembrane protein 64
chr4_-_149377238 5.064 H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr3_-_142054771 5.034 NM_001190857
NM_022554
Pdlim5

PDZ and LIM domain 5

chr13_-_117814079 4.957 Parp8
poly (ADP-ribose) polymerase family, member 8
chr9_+_108417075 4.721 Qars
glutaminyl-tRNA synthetase
chr17_+_35187325 4.688 Clic1
chloride intracellular channel 1
chr16_-_97684510 4.601 NM_010846
Mx1
myxovirus (influenza virus) resistance 1
chr5_+_115373333 4.582 Oasl1
2'-5' oligoadenylate synthetase-like 1
chr17_-_36282006 4.522 H2-D1
histocompatibility 2, D region locus 1
chr13_-_101017247 4.487 NM_010870
Naip5
NLR family, apoptosis inhibitory protein 5
chr5_-_141476549 4.376 NM_175362
Card11
caspase recruitment domain family, member 11
chr7_-_52391649 4.250 Flt3l
FMS-like tyrosine kinase 3 ligand
chr8_-_46495663 4.223 Tlr3
toll-like receptor 3
chr11_-_120434204 4.132 NM_011032
P4hb
prolyl 4-hydroxylase, beta polypeptide
chr2_-_132078946 4.027 Pcna
proliferating cell nuclear antigen
chr18_-_42110847 4.023 NM_029942
Prelid2
PRELI domain containing 2
chr12_+_111685516 4.018 Ppp2r5c
protein phosphatase 2, regulatory subunit B (B56), gamma isoform
chr10_+_127759512 4.000 NM_019953
Cnpy2
canopy 2 homolog (zebrafish)
chr7_-_148354562 3.921 NM_001172101
NM_145135
Rnh1

ribonuclease/angiogenin inhibitor 1

chr13_-_100972022 3.870 NM_001126182
NM_010872
Naip2

NLR family, apoptosis inhibitory protein 2

chr10_-_29255606 3.794 NM_028351
Rspo3
R-spondin 3 homolog (Xenopus laevis)
chr9_+_108410335 3.720 NM_133794
Qars
glutaminyl-tRNA synthetase
chr8_-_46495958 3.717 Tlr3
toll-like receptor 3
chr13_+_34254827 3.681 NM_001101430
NM_001110515
Psmg4

proteasome (prosome, macropain) assembly chaperone 4

chr8_-_46495890 3.667 NM_126166
Tlr3
toll-like receptor 3
chr5_-_105482574 3.575 NM_029509
Gbp8
guanylate-binding protein 8
chr4_+_86394436 3.567 NM_001081014
NM_184088
Dennd4c

DENN/MADD domain containing 4C

chr4_-_118954780 3.540 Ybx1
Y box protein 1
chr2_+_4480799 3.438 NM_001177844
Frmd4a
FERM domain containing 4A
chr13_-_31065909 3.370 NM_025588
Exoc2
exocyst complex component 2
chr11_-_99016390 3.333 NM_007719
Ccr7
chemokine (C-C motif) receptor 7
chr2_+_32391249 3.306 Fam102a
family with sequence similarity 102, member A
chr18_+_83084023 3.136 NM_001177464
Zfp516
zinc finger protein 516
chr6_+_34813131 3.026 NM_197986
Tmem140
transmembrane protein 140
chr7_+_97535516 3.006 Sytl2
synaptotagmin-like 2
chr11_+_4167080 3.006 NM_001039537
Lif
leukemia inhibitory factor
chr10_+_127759640 2.974 Cnpy2
canopy 2 homolog (zebrafish)
chr3_-_58905678 2.840 NM_173398
Gpr171
G protein-coupled receptor 171
chr13_+_34254902 2.794 Psmg4
proteasome (prosome, macropain) assembly chaperone 4
chr18_+_89366818 2.737 NM_001039149
NM_178687
Cd226

CD226 antigen

chr2_+_27741864 2.698 NM_015734
Col5a1
collagen, type V, alpha 1
chr18_-_52689504 2.602 Lox
lysyl oxidase
chr12_-_86644527 2.544 Nek9
NIMA (never in mitosis gene a)-related expressed kinase 9
chr2_-_132078887 2.530 NM_011045
Pcna
proliferating cell nuclear antigen
chr7_+_97535490 2.443 NM_001040087
NM_001040088
Sytl2

synaptotagmin-like 2

chr1_-_185857753 2.409 NM_028516
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr14_+_56188462 2.319


chr11_-_61058671 2.310


chr13_-_101087625 2.303 NM_021545
Naip6
Naip7
NLR family, apoptosis inhibitory protein 6
NLR family, apoptosis inhibitory protein 7
chr10_+_117878101 2.265 NM_008337
Ifng
interferon gamma
chr15_+_77307476 2.241 NM_177744
Apol10a
apolipoprotein L 10a
chr11_-_120434075 2.206 P4hb
prolyl 4-hydroxylase, beta polypeptide
chr6_-_71582562 2.163 NM_173001
Kdm3a
lysine (K)-specific demethylase 3A
chr4_-_124359695 2.120 Utp11l
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr9_+_35024031 2.078 Srpr
signal recognition particle receptor ('docking protein')
chr2_-_51790406 2.044 NM_001141981
NM_030243
Rbm43

RNA binding motif protein 43

chr2_+_145648290 2.032 Rin2
Ras and Rab interactor 2
chr15_+_25772997 2.027 NM_001034851
Fam134b
family with sequence similarity 134, member B
chr9_-_50425561 1.976 NM_001134902
NM_212449
AU019823

expressed sequence AU019823

chr1_+_45401659 1.960 Col3a1
collagen, type III, alpha 1
chr9_+_114239252 1.953 NM_007535
Bcl2a1c
B-cell leukemia/lymphoma 2 related protein A1c
chr17_+_30763879 1.947 NM_013811
Dnahc8
dynein, axonemal, heavy chain 8
chr10_-_36855292 1.946 Marcks
myristoylated alanine rich protein kinase C substrate
chr3_-_9833502 1.943 NM_001195031
NM_053182
Pag1

phosphoprotein associated with glycosphingolipid microdomains 1

chr9_-_37063214 1.939 NM_001145960
NM_020258
Slc37a2

solute carrier family 37 (glycerol-3-phosphate transporter), member 2

chr8_+_91220959 1.894 Cyld
cylindromatosis (turban tumor syndrome)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.02 6.86e-11 GO:0002376 immune system process
5.59 2.36e-08 GO:0006955 immune response
4.08 1.09e-06 GO:0002682 regulation of immune system process
15.63 4.59e-06 GO:0019882 antigen processing and presentation
21.07 2.74e-05 GO:0034341 response to interferon-gamma
6.29 1.36e-03 GO:0045087 innate immune response
3.91 1.68e-03 GO:0009607 response to biotic stimulus
3.47 2.40e-03 GO:0006952 defense response
4.22 2.72e-03 GO:0051707 response to other organism
1.83 5.68e-03 GO:0048518 positive regulation of biological process
4.67 9.95e-03 GO:0002694 regulation of leukocyte activation
4.48 1.52e-02 GO:0050865 regulation of cell activation
5.38 1.65e-02 GO:0002697 regulation of immune effector process
24.08 1.67e-02 GO:0071346 cellular response to interferon-gamma
22.57 2.21e-02 GO:0001562 response to protozoan
22.57 2.21e-02 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
22.57 2.21e-02 GO:0042832 defense response to protozoan
45.14 2.43e-02 GO:0032823 regulation of natural killer cell differentiation
45.14 2.43e-02 GO:0032825 positive regulation of natural killer cell differentiation
1.81 3.17e-02 GO:0048522 positive regulation of cellular process
1.83 3.44e-02 GO:0048519 negative regulation of biological process
5.35 4.54e-02 GO:0002696 positive regulation of leukocyte activation
19.01 4.59e-02 GO:0032814 regulation of natural killer cell activation
4.00 4.61e-02 GO:0019941 modification-dependent protein catabolic process
3.97 4.94e-02 GO:0043632 modification-dependent macromolecule catabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.64 6.08e-04 GO:0044421 extracellular region part
19.01 7.86e-03 GO:0005839 proteasome core complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
21.25 5.78e-03 GO:0003950 NAD+ ADP-ribosyltransferase activity
17.20 1.41e-02 GO:0004298 threonine-type endopeptidase activity
17.20 1.41e-02 GO:0070003 threonine-type peptidase activity
1.43 1.95e-02 GO:0005515 protein binding
4.52 3.35e-02 GO:0005125 cytokine activity