Motif ID: RBPJ.p2

Z-value: 0.875


Transcription factors associated with RBPJ.p2:

Gene SymbolEntrez IDGene Name
Rbpj 19664 recombination signal binding protein for immunoglobulin kappa J region

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rbpjchr5_+_53981893-0.241.0e-03Click!


Activity profile for motif RBPJ.p2.

activity profile for motif RBPJ.p2


Sorted Z-values histogram for motif RBPJ.p2

Sorted Z-values for motif RBPJ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RBPJ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_69989168 8.984 Fam81a
family with sequence similarity 81, member A
chr9_-_69989285 8.216 NM_029784
Fam81a
family with sequence similarity 81, member A
chr2_+_180195682 6.406 NM_148933
Slco4a1
solute carrier organic anion transporter family, member 4a1
chr4_+_154335029 6.343 NM_010419
Hes5
hairy and enhancer of split 5 (Drosophila)
chr7_-_126602780 5.611 NM_025989
Gp2
glycoprotein 2 (zymogen granule membrane)
chr5_-_113510602 4.341 NM_001159650
NM_021352
Crybb3

crystallin, beta B3

chr2_-_69424085 4.337 NM_001081088
Lrp2
low density lipoprotein receptor-related protein 2
chr6_-_91423388 4.163 NM_133928
Chchd4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr7_+_29325883 4.084 NM_026716
Sycn
syncollin
chr10_+_122116066 4.010 Ppm1h
protein phosphatase 1H (PP2C domain containing)
chr19_+_53966720 3.761 NM_011050
Pdcd4
programmed cell death 4
chr1_-_65097587 3.637 NM_007777
Cryge
crystallin, gamma E
chr15_-_85864206 3.583 NM_009886
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr17_-_25393220 3.541 NM_001163270
Baiap3
BAI1-associated protein 3
chr15_+_75824198 3.436 NM_177922
Mapk15
mitogen-activated protein kinase 15
chr9_+_19426528 3.401 NM_172918
Zfp317
zinc finger protein 317
chr1_+_74726341 3.323 Ttll4
tubulin tyrosine ligase-like family, member 4
chr6_+_30589217 3.268 NM_025350
Cpa1
carboxypeptidase A1
chr1_+_89223558 3.118 NM_146112
NM_001110212
Gigyf2

GRB10 interacting GYF protein 2

chr6_+_30589440 2.912 Cpa1
carboxypeptidase A1
chr11_-_69050508 2.857 NM_008192
Gucy2e
guanylate cyclase 2e
chr4_+_155577378 2.857 AW011738
expressed sequence AW011738
chr7_+_51443605 2.850 NM_010643
Klk1b24
kallikrein 1-related peptidase b24
chr8_-_107033781 2.802 NM_180958
Ccdc79
coiled-coil domain containing 79
chr5_-_110772051 2.771 NM_001164833
NM_001164834
NM_153400
P2rx2


purinergic receptor P2X, ligand-gated ion channel, 2


chrX_+_91480268 2.742 NM_001039059
NM_001039060
NM_001039061
NM_153165
Klhl15



kelch-like 15 (Drosophila)



chr4_-_59973470 2.739 NM_008648
Mup4
major urinary protein 4
chr6_-_78328836 2.692 NM_001161741
NM_013893
Reg3d

regenerating islet-derived 3 delta

chr7_-_30857837 2.689 NM_177889
Zfp82
zinc finger protein 82
chr4_-_106850812 2.632 NM_025617
2210012G02Rik
RIKEN cDNA 2210012G02 gene
chr2_+_167906462 2.624 NM_021409
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr16_+_30065419 2.572 NM_008235
Hes1
hairy and enhancer of split 1 (Drosophila)
chr11_-_69694379 2.571 NM_153143
Kctd11
potassium channel tetramerisation domain containing 11
chr7_-_51926142 2.487 Myh14
myosin, heavy polypeptide 14
chr18_-_20160536 2.417 NM_007882
Dsc3
desmocollin 3
chr2_+_24132788 2.350 NM_019451
Il1f5
interleukin 1 family, member 5 (delta)
chr12_-_113146259 2.306 NM_011625
Ppp1r13b
protein phosphatase 1, regulatory (inhibitor) subunit 13B
chr2_+_130401908 2.232 NM_011025
Oxt
oxytocin
chr13_+_67914748 2.228 NM_198322
Zfp273
zinc finger protein 273
chrX_-_101176600 2.228 NM_011276
Rlim
ring finger protein, LIM domain interacting
chr17_-_35837432 2.202 NM_001198833
Ddr1
discoidin domain receptor family, member 1
chrX_+_55283804 2.196 NM_009575
Zic3
zinc finger protein of the cerebellum 3
chr7_+_13512764 2.165 NM_029809
2310014L17Rik
RIKEN cDNA 2310014L17 gene
chr1_+_184695026 2.153 NM_144796
Susd4
sushi domain containing 4
chr14_+_57430806 2.146 2410022M11Rik
RIKEN cDNA 2410022M11 gene
chr1_+_173489323 2.118 NM_018729
Cd244
LOC677008
CD244 natural killer cell receptor 2B4
natural killer cell receptor 2B4-like
chr11_+_51103421 2.116 NM_153393
Col23a1
collagen, type XXIII, alpha 1
chr3_+_121747377 2.101 NM_007378
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr4_+_43519895 2.092 NM_139305
Car9
carbonic anhydrase 9
chr7_+_51307659 2.087 NM_020268
Klk1b27
kallikrein 1-related peptidase b27
chr4_-_45024999 2.085 NM_001163283
NM_001163284
NM_173399
Zbtb5


zinc finger and BTB domain containing 5


chr17_-_26122588 2.065 Solh
small optic lobes homolog (Drosophila)
chr7_-_104886756 2.052 NM_175105
Aqp11
aquaporin 11
chr11_-_50700944 1.995 NM_172794
Zfp454
zinc finger protein 454
chr2_-_155660587 1.969 NM_027788
Fam83c
family with sequence similarity 83, member C
chr9_-_114549148 1.951 NM_153585
Cnot10
CCR4-NOT transcription complex, subunit 10
chr9_-_114549261 1.933 Cnot10
CCR4-NOT transcription complex, subunit 10
chr13_-_67433435 1.931 NM_177622
Zfp595
zinc finger protein 595
chr10_+_125403274 1.906 NM_177152
Lrig3
leucine-rich repeats and immunoglobulin-like domains 3
chr4_+_56815248 1.900 BC026590
cDNA sequence BC026590
chr16_+_36277233 1.882 NM_001082543
Stfa1
stefin A1
chr7_-_53080056 1.858 NM_145963
Kcnj14
potassium inwardly-rectifying channel, subfamily J, member 14
chr11_+_79153388 1.856 NM_010897
Nf1
neurofibromatosis 1
chr7_+_30768973 1.843 NM_001033355
NM_001167872
NM_001167873
Zfp568


zinc finger protein 568


chr4_-_125879832 1.840 NM_146153
Thrap3
thyroid hormone receptor associated protein 3
chr12_-_101397818 1.825 NM_183155
BC002230
cDNA sequence BC002230
chr4_+_56756283 1.808 NM_009611
Actl7a
actin-like 7a
chr16_-_96304116 1.785 Brwd1
bromodomain and WD repeat domain containing 1
chr7_+_4972164 1.774 Zfp865
zinc finger protein 865
chr11_+_59120429 1.758 NM_139298
Wnt9a
wingless-type MMTV integration site 9A
chr12_-_4483975 1.751 Ncoa1
nuclear receptor coactivator 1
chr7_-_148399978 1.750 NM_028050
1600016N20Rik
RIKEN cDNA 1600016N20 gene
chr17_-_26122737 1.743 Solh
small optic lobes homolog (Drosophila)
chr16_+_41533317 1.733 NM_175548
Lsamp
limbic system-associated membrane protein
chr18_-_46685557 1.733 NM_173423
Fem1c
fem-1 homolog c (C.elegans)
chr4_+_114761312 1.729 NM_001164557
NM_001164558
NM_026018
Pdzk1ip1


PDZK1 interacting protein 1


chr13_-_67585160 1.712 NM_001076791
Zfp874b
zinc finger protein 874b
chr19_-_42007761 1.703 NM_001164561
NM_025644
Exosc1

exosome component 1

chr17_+_71533317 1.696 NM_022882
Lpin2
lipin 2
chr8_+_109127245 1.695 NM_009864
Cdh1
cadherin 1
chr5_+_148241736 1.690 Pan3
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr9_+_123387818 1.689 NM_013860
Limd1
LIM domains containing 1
chr8_-_108734817 1.662 NM_001007567
Slc7a6os
solute carrier family 7, member 6 opposite strand
chr10_-_129717244 1.655 NM_007501
Neurod4
neurogenic differentiation 4
chr1_-_193399352 1.654 Dtl
denticleless homolog (Drosophila)
chr5_-_151468105 1.649 NM_201369
N4bp2l2
NEDD4 binding protein 2-like 2
chr1_-_59820157 1.625 B430105G09Rik
RIKEN cDNA B430105G09 gene
chr18_+_74893369 1.617 Myo5b
myosin VB
chr7_-_116867284 1.615 NM_001040700
BC051019
cDNA sequence BC051019
chr5_+_77739506 1.583 NM_153798
Polr2b
polymerase (RNA) II (DNA directed) polypeptide B
chr14_-_57190668 1.580 NM_001014996
Cenpj
centromere protein J
chr3_-_82707816 1.579 Lrat
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
chr7_-_26022753 1.575 NM_001031667
Gsk3a
glycogen synthase kinase 3 alpha
chr7_+_95578782 1.573 NM_028238
Rab38
RAB38, member of RAS oncogene family
chr4_-_155571450 1.565 Agrn
agrin
chr7_+_129008551 1.562 NM_011325
Scnn1b
sodium channel, nonvoltage-gated 1 beta
chr11_-_120314753 1.562 NM_012065
Pde6g
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr9_+_106724228 1.559 NM_001015507
Vprbp
Vpr (HIV-1) binding protein
chr7_-_138289796 1.552 NM_173409
4933402N03Rik
RIKEN cDNA 4933402N03 gene
chr13_-_67461473 1.545 NM_001038651
Zfp953
zinc finger protein 953
chr13_-_67370003 1.526 NM_001001152
Zfp458
zinc finger protein 458
chr14_+_49686169 1.525 NM_144535
Mudeng
MU-2/AP1M2 domain containing, death-inducing
chr12_+_37108036 1.507 NM_178629
Ispd
isoprenoid synthase domain containing
chr1_+_133724553 1.504 NM_173865
Slc41a1
solute carrier family 41, member 1
chr19_-_46747463 1.502 NM_007809
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
chr9_+_43915391 1.497 NM_001190319
C1qtnf5
C1q and tumor necrosis factor related protein 5
chr13_+_21570775 1.496 NM_001039115
Zkscan4
zinc finger with KRAB and SCAN domains 4
chr19_+_58803376 1.492 NM_018874
Pnliprp1
pancreatic lipase related protein 1
chr7_+_51357661 1.462 NM_010642
Klk1b21
kallikrein 1-related peptidase b21
chr2_+_154132962 1.449 NM_001025574
5430413K10Rik
RIKEN cDNA 5430413K10 gene
chr7_+_6124083 1.445 NM_001146024
NM_028316
Zfp444

zinc finger protein 444

chr4_+_106851234 1.444 NM_029565
Tmem59
transmembrane protein 59
chrX_-_101866123 1.431 Zdhhc15
zinc finger, DHHC domain containing 15
chr14_-_56503083 1.426 NM_019820
Cbln3
cerebellin 3 precursor protein
chr12_+_74040868 1.425 NM_011384
Six6
sine oculis-related homeobox 6 homolog (Drosophila)
chr18_-_32299223 1.425 NM_001042767
Proc
protein C
chr7_-_52003986 1.417 NM_178734
Zfp473
zinc finger protein 473
chr13_-_67162084 1.414 NM_001166218
Zfp712
zinc finger protein 712
chr2_+_164228640 1.395 NM_009036
Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr7_+_4971977 1.395 NM_001033383
Zfp865
zinc finger protein 865
chr14_+_35487052 1.394 NM_001004436
Wapal
wings apart-like homolog (Drosophila)
chr6_-_122436294 1.390 NM_027664
Rimklb
ribosomal modification protein rimK-like family member B
chr2_-_156712810 1.390 NM_029983
Sla2
Src-like-adaptor 2
chr2_-_164571430 1.386 Wfdc3
WAP four-disulfide core domain 3
chr16_-_36367622 1.382 NM_001082546
BC100530
BC117090
cDNA sequence BC100530
cDNA sequence BC1179090
chr10_-_13588578 1.382 NM_025446
Aig1
androgen-induced 1
chr9_+_64659238 1.380 Dennd4a
DENN/MADD domain containing 4A
chr13_-_67407347 1.363 NM_001003666
Zfp457
zinc finger protein 457
chr2_+_154439056 1.351 NM_199304
Zfp341
zinc finger protein 341
chr15_-_75812322 1.347 2410075B13Rik
RIKEN cDNA 2410075B13 gene
chr7_-_135381486 1.330 NM_177001
9130023H24Rik
RIKEN cDNA 9130023H24 gene
chr8_+_77517536 1.319 NM_178017
Hmgxb4
HMG box domain containing 4
chr19_+_7457020 1.317 1700105P06Rik
RIKEN cDNA 1700105P06 gene
chr7_-_30638635 1.313 NM_173738
Zfp940
zinc finger protein 940
chr2_+_22923653 1.305 NM_001102436
NM_028793
Acbd5

acyl-Coenzyme A binding domain containing 5

chr12_-_113146249 1.301 Ppp1r13b
protein phosphatase 1, regulatory (inhibitor) subunit 13B
chr16_+_13903253 1.293 Mpv17l
Mpv17 transgene, kidney disease mutant-like
chr8_+_72566711 1.289 NM_027481
Sugp1
SURP and G patch domain containing 1
chrX_+_6645338 1.289 NM_001042542
Akap4
A kinase (PRKA) anchor protein 4
chrX_+_136219520 1.282 NM_001081499
Tbc1d8b
TBC1 domain family, member 8B
chr17_-_79336374 1.278 NM_001024806
Cebpz
CCAAT/enhancer binding protein zeta
chr3_-_53267127 1.268 NM_172501
Nhlrc3
NHL repeat containing 3
chr15_-_98638348 1.267 NM_001013741
Ddn
dendrin
chr1_+_132697478 1.262 NM_001170632
NM_144960
Fcamr

Fc receptor, IgA, IgM, high affinity

chr18_-_34738725 1.254 NM_080637
Nme5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr2_-_34813680 1.243 Traf1
TNF receptor-associated factor 1
chr1_+_195128163 1.233 NM_008484
Lamb3
laminin, beta 3
chrX_-_35988248 1.232 C1galt1c1
C1GALT1-specific chaperone 1
chr2_-_34813633 1.227 Traf1
TNF receptor-associated factor 1
chr11_+_14499242 1.226 NM_001164166
Pom121l12
POM121 membrane glycoprotein-like 12
chr8_+_72566937 1.225 Sugp1
SURP and G patch domain containing 1
chrX_-_159987479 1.221 NM_008177
Grpr
gastrin releasing peptide receptor
chr11_-_3763899 1.217 NM_152818
Osbp2
oxysterol binding protein 2
chr5_+_115777174 1.215 NM_025573
Srsf9
serine/arginine-rich splicing factor 9
chrX_+_7156801 1.211 NM_054039
Foxp3
forkhead box P3
chr8_+_72346327 1.205 NM_020028
Lpar2
lysophosphatidic acid receptor 2
chr11_+_68970573 1.201 NM_009659
Alox12b
arachidonate 12-lipoxygenase, 12R type
chr17_-_47147501 1.196 Ubr2
C79242
ubiquitin protein ligase E3 component n-recognin 2
expressed sequence C79242
chr15_-_54903657 1.189 NM_001081288
Taf2
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_-_92210955 1.187 NM_001166633
NM_172670
Gyltl1b

glycosyltransferase-like 1B

chr9_+_107830799 1.185 NM_026338
4921517D21Rik
RIKEN cDNA 4921517D21 gene
chr8_+_19784703 1.169 2610005L07Rik
A430108E01Rik
cadherin 11 pseudogene
RIKEN cDNA A430108E01 gene
chr9_+_107790512 1.165 Mon1a
MON1 homolog A (yeast)
chr10_+_21097094 1.162 NM_178713
Aldh8a1
aldehyde dehydrogenase 8 family, member A1
chr14_-_56503058 1.161 Cbln3
cerebellin 3 precursor protein
chr6_-_148894953 1.160 NM_019643
Fam60a
family with sequence similarity 60, member A
chr19_+_32463705 1.160 2700046G09Rik
RIKEN cDNA 2700046G09 gene
chr7_-_6649139 1.158 NM_011769
Zim1
zinc finger, imprinted 1
chr5_+_73039082 1.155 Nipal1
NIPA-like domain containing 1
chr4_+_40419212 1.154 NM_177175
Tmem215
transmembrane protein 215
chr16_-_55838747 1.147 NM_001159395
NM_030612
Nfkbiz

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta

chr7_+_135381536 1.139 Armc5
armadillo repeat containing 5
chr18_-_34784206 1.139 Brd8
bromodomain containing 8
chr12_+_8797502 1.136


chr2_-_165060352 1.122 Cdh22
cadherin 22
chr14_+_31699648 1.121 NM_001159299
NM_018746
Itih4

inter alpha-trypsin inhibitor, heavy chain 4

chr15_-_34608458 1.119 NM_145469
Nipal2
NIPA-like domain containing 2
chr18_+_31793991 1.116 NM_172965
Sap130
Sin3A associated protein
chr6_+_146798631 1.115 NM_027059
1700023A16Rik
RIKEN cDNA 1700023A16 gene
chr6_-_85854877 1.110 NM_029331
1700019G17Rik
RIKEN cDNA 1700019G17 gene
chr6_-_91713072 1.105 Grip2
glutamate receptor interacting protein 2
chr9_+_27204405 1.102 NM_029299
Spata19
spermatogenesis associated 19
chr6_+_21899614 1.099 NM_023626
Ing3
inhibitor of growth family, member 3
chr10_+_120834091 1.087


chr16_+_96502595 1.086 NM_033149
B3galt5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr1_-_193399412 1.084 NM_029766
Dtl
denticleless homolog (Drosophila)
chr8_+_19784580 1.083 A430108E01Rik
RIKEN cDNA A430108E01 gene
chr9_-_50554613 1.077 NM_025865
2310030G06Rik
RIKEN cDNA 2310030G06 gene
chr5_+_3543815 1.075 NM_001042501
Fam133b
family with sequence similarity 133, member B
chr11_+_78317000 1.072 NM_008759
Sebox
SEBOX homeobox
chr11_+_113545719 1.070 NM_177777
D11Wsu47e
DNA segment, Chr 11, Wayne State University 47, expressed
chrX_+_96331434 1.070 NM_010110
Efnb1
ephrin B1
chr6_+_78375973 1.065 NM_009042
Reg1
regenerating islet-derived 1
chr9_-_50369372 1.065 NM_025687
Tex12
testis expressed gene 12
chr7_+_86418127 1.063 NM_018811
Abhd2
abhydrolase domain containing 2
chr1_-_129574328 1.060 Tmem163
transmembrane protein 163
chr2_-_60511707 1.060 NM_021359
Itgb6
integrin beta 6
chr6_-_23600205 1.058 NM_198251
Rnf133
ring finger protein 133
chr4_-_22415444 1.057 Pou3f2
POU domain, class 3, transcription factor 2
chr15_-_98638230 1.053 Ddn
dendrin

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.45 2.39e-05 GO:0010467 gene expression
1.45 1.07e-04 GO:0016070 RNA metabolic process
1.41 1.22e-04 GO:0090304 nucleic acid metabolic process
1.26 2.66e-04 GO:0043170 macromolecule metabolic process
1.28 5.09e-04 GO:0044260 cellular macromolecule metabolic process
1.51 5.21e-04 GO:0006351 transcription, DNA-dependent
1.51 5.81e-04 GO:0032774 RNA biosynthetic process
1.39 2.44e-03 GO:0034645 cellular macromolecule biosynthetic process
1.40 2.94e-03 GO:0006355 regulation of transcription, DNA-dependent
1.36 4.13e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 4.22e-03 GO:0009059 macromolecule biosynthetic process
1.39 4.53e-03 GO:0051252 regulation of RNA metabolic process
1.35 5.71e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.31 8.26e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 1.78e-02 GO:0031323 regulation of cellular metabolic process
1.29 1.79e-02 GO:0060255 regulation of macromolecule metabolic process
1.34 1.92e-02 GO:0010468 regulation of gene expression
1.28 2.06e-02 GO:0080090 regulation of primary metabolic process
1.26 2.30e-02 GO:0019222 regulation of metabolic process
1.33 3.61e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.28 1.80e-05 GO:0005634 nucleus

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.37 6.37e-06 GO:0043169 cation binding
1.37 7.70e-06 GO:0046872 metal ion binding
1.37 8.99e-06 GO:0043167 ion binding
1.15 2.39e-05 GO:0005488 binding
1.51 2.06e-04 GO:0046914 transition metal ion binding
1.56 3.92e-04 GO:0008270 zinc ion binding
1.31 1.78e-02 GO:0003676 nucleic acid binding