• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: REST.p3

Z-value: 5.393

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_132607432	274.238		Chgb	chromogranin B
chr2_+_132607013	274.060	NM_007694	Chgb	chromogranin B
chr2_+_132607398	269.078		Chgb	chromogranin B
chr2_+_132607408	267.647		Chgb	chromogranin B
chr2_-_181049204	260.292	NM_009133	Stmn3	stathmin-like 3
chr2_-_181048957	254.386		Stmn3	stathmin-like 3
chr16_-_23890909	243.530	NM_009215	Sst	somatostatin
chr6_-_121423633	223.441		Iqsec3	IQ motif and Sec7 domain 3
chrX_+_7215705	214.562	NM_009305	Syp	synaptophysin
chr18_-_31606908	203.883	NM_009308	Syt4	synaptotagmin IV
chr3_-_80606500	201.906		Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr2_+_164793698	198.509		Slc12a5	solute carrier family 12, member 5
chr1_-_84692750	191.074	NM_152915	Dner	delta/notch-like EGF-related receptor
chr6_-_121423682	190.570	NM_001033354	Iqsec3	IQ motif and Sec7 domain 3
chr12_+_103793130	188.428	NM_007693	Chga	chromogranin A
chr4_-_128798481	187.735	NM_010471	Hpca	hippocalcin
chr1_-_84692352	185.430		Dner	delta/notch-like EGF-related receptor
chrX_-_20498021	174.139	NM_001110780 NM_013680	Syn1	synapsin I
chr11_-_35612385	165.999	NM_001004147	Fbll1	fibrillarin-like 1
chr5_+_137506122	157.171	NM_001039385	Vgf	VGF nerve growth factor inducible
chr3_-_80606704	154.941	NM_001039195 NM_001083806 NM_013540	Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr5_-_121459496	145.759	NM_011286	Rph3a	rabphilin 3A
chr1_-_177422630	145.460	NM_001199003 NM_011880	Rgs7	regulator of G protein signaling 7
chr4_+_101223198	145.049	NM_001164583	Dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr11_-_35612058	144.365		Fbll1	fibrillarin-like 1
chr12_-_113749361	143.847		Tmem179	transmembrane protein 179
chr3_-_80606641	139.985		Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr7_+_28438881	139.830	NM_028417	Ttc9b	tetratricopeptide repeat domain 9B
chr12_-_113749313	137.121		Tmem179	transmembrane protein 179
chr11_+_102254949	134.568		Rundc3a	RUN domain containing 3A
chr11_+_102254816	133.191		Rundc3a	RUN domain containing 3A
chr12_-_113749363	128.899	NM_178915	Tmem179	transmembrane protein 179
chr2_+_164793796	125.235		Slc12a5	solute carrier family 12, member 5
chr4_-_4065205	123.610		Penk	preproenkephalin
chr2_-_92241282	122.977		Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1
chr2_+_22478062	116.323		Gad2	glutamic acid decarboxylase 2
chr2_-_92241357	114.221	NM_011162	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1
chr2_+_22478131	113.265		Gad2	glutamic acid decarboxylase 2
chr11_+_102254699	113.122	NM_016759	Rundc3a	RUN domain containing 3A
chr2_-_25174498	111.242		Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr3_+_67868723	107.287	NM_001113420 NM_001113421	Schip1	schwannomin interacting protein 1
chr4_+_15808409	106.684	NM_009788	Calb1	calbindin 1
chr12_-_71448300	103.462		Trim9	tripartite motif-containing 9
chr7_+_58877199	100.479	NM_080853	Slc17a6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr2_-_25174662	97.670	NM_001177656 NM_001177657 NM_008169	Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr13_-_100670595	95.890	NM_001081493 NM_013732	Cartpt	CART prepropeptide
chr9_+_104472090	95.534	NM_028719	Cpne4	copine IV
chr7_-_88638789	94.668	NM_021492	Ap3b2	adaptor-related protein complex 3, beta 2 subunit
chr2_+_22477837	94.430	NM_008078	Gad2	glutamic acid decarboxylase 2
chr5_-_121459315	89.814		Rph3a	rabphilin 3A
chr7_-_28181562	89.301		Spnb4	spectrin beta 4
chr9_+_40076800	86.266	NM_001083917 NM_153522 NM_178227	Scn3b	sodium channel, voltage-gated, type III, beta
chr9_+_108728650	84.417	NM_080437	Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr15_-_76552594	83.530	NM_198119	Lrrc24	leucine rich repeat containing 24
chr11_+_80290571	82.418		Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr6_+_8898613	81.103		Nxph1	neurexophilin 1
chr16_-_37385024	72.609	NM_001114611 NM_001114612 NM_001114613 NM_172440	Stxbp5l	syntaxin binding protein 5-like
chr9_-_57315800	72.391	NM_020270	Scamp5	secretory carrier membrane protein 5
chr10_-_4707228	71.574	NM_011702	Vip	vasoactive intestinal polypeptide
chr10_+_90292388	68.670		Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_177422520	68.216		Rgs7	regulator of G protein signaling 7
chr12_-_71448600	65.838	NM_001110202 NM_001110203 NM_053167	Trim9	tripartite motif-containing 9
chr6_+_113232319	65.576		Cpne9	copine family member IX
chr6_-_134837738	65.454	NM_001167697 NM_001167699 NM_008157	Gpr19	G protein-coupled receptor 19
chr11_+_80290509	64.726	NM_009871	Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr13_+_54472705	58.851	NM_009946	Cplx2	complexin 2
chr2_-_79294977	56.825		Neurod1	neurogenic differentiation 1
chr7_+_70589623	52.566	NM_130880	Otud7a	OTU domain containing 7A
chr1_+_34636537	51.751	NM_213727	Fam123c	family with sequence similarity 123, member C
chr11_+_77744280	50.466	NM_021286	Sez6	seizure related gene 6
chr4_+_12833983	49.328	NM_001171801 NM_173746	Gm11818	predicted gene 11818
chr2_+_25719373	49.316	NM_001145403	Kcnt1	potassium channel, subfamily T, member 1
chr6_+_113232300	47.852	NM_170673	Cpne9	copine family member IX
chr19_+_42330170	41.416	NM_027694	Golga7b	golgi autoantigen, golgin subfamily a, 7B
chr7_+_108570359	40.860		Pde2a	phosphodiesterase 2A, cGMP-stimulated
chr13_-_105844882	40.647	NM_029879	Rgs7bp	regulator of G-protein signalling 7 binding protein
chr17_-_91492065	40.513	NM_020252 NM_177284	Nrxn1	neurexin I
chr12_-_86039703	38.872	NM_001033334	Tmem90a	transmembrane protein 90a
chr7_+_26102182	38.255	NM_001160400	Megf8	multiple EGF-like-domains 8
chr12_+_117724182	35.154	NM_011215	Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr17_-_25377052	34.871	NM_172529	Gnptg	N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr17_+_70318387	33.357		Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr14_+_66587319	31.697	NM_013492	Clu	clusterin
chr7_-_88638540	30.788		Ap3b2	adaptor-related protein complex 3, beta 2 subunit
chr9_+_59426108	30.750	NM_175235	Celf6	CUGBP, Elav-like family member 6
chr3_+_94282235	29.854		Celf3	VCUGBP, Elav-like family member 3
chr17_+_70318530	27.109		Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr17_-_23877115	25.957	NM_023824	Paqr4	progestin and adipoQ receptor family member IV
chr3_+_114606995	25.192	NM_153458	Olfm3	olfactomedin 3
chr13_-_54850954	24.462	NM_012014	Gprin1	G protein-regulated inducer of neurite outgrowth 1
chr10_+_90292453	24.416		Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr3_-_89568552	23.296	NM_009602	Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr2_-_179839111	23.282		Hrh3	histamine receptor H3
chr2_-_179838878	22.485	NM_133849	Hrh3	histamine receptor H3
chr4_+_128814102	21.348	NM_027402	Fndc5	fibronectin type III domain containing 5
chr17_+_28712663	19.473	NM_026571	Lhfpl5	lipoma HMGIC fusion partner-like 5
chr13_+_45602853	18.675		Gmpr	guanosine monophosphate reductase
chr3_-_89568298	17.518		Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr2_+_139996419	17.193		2310003L22Rik	RIKEN cDNA 2310003L22 gene
chr2_+_139996381	15.742	NM_027093	2310003L22Rik	RIKEN cDNA 2310003L22 gene
chr4_-_152856922	13.912	NM_001099299	Ajap1	adherens junction associated protein 1
chr13_+_45602825	13.500	NM_025508	Gmpr	guanosine monophosphate reductase
chr11_+_58144207	11.746	NM_001161338 NM_024480	Sh3bp5l	SH3 binding domain protein 5 like
chr4_-_135050358	10.782	NM_028995	Nipal3	NIPA-like domain containing 3
chr17_+_70318707	10.666		Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr9_+_122026424	10.131		Snrk	SNF related kinase
chr7_-_20189709	10.109	NM_016680	Clasrp	CLK4-associating serine/arginine rich protein
chr13_+_45602909	9.972		Gmpr	guanosine monophosphate reductase
chr11_+_74433092	7.599	NM_001013784	E130309D14Rik	RIKEN cDNA E130309D14 gene
chr8_+_18846262	7.579	NM_026792	Agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr8_-_69211936	7.288	NM_016708	Npy5r	neuropeptide Y receptor Y5
chr16_-_17576750	7.100	NM_144852	Slc7a4	solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
chr17_-_71339826	6.820	NM_023402	Myl12b	myosin, light chain 12B, regulatory
chr19_+_5038825	6.131	NM_175383	B3gnt1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr2_-_26997965	5.271	NM_175427	Fam163b	family with sequence similarity 163, member B
chr15_+_101303908	4.584	NM_010667	Krt86	keratin 86
chrX_-_100103981	4.405	NM_027591	Dmrtc1a	DMRT-like family C1a
chr12_+_117724251	4.318		Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr11_-_115465172	4.188	NM_173048	Gga3	golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr17_-_46841925	3.988	NM_009358	Ppp2r5d	protein phosphatase 2, regulatory subunit B (B56), delta isoform
chr16_-_45742995	3.374	NM_172511	Abhd10	abhydrolase domain containing 10
chr2_+_174123359	3.065	NM_001077507 NM_010309 NM_201617 NM_201618	Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr9_-_21889810	3.057	NM_012029	Ecsit	ECSIT homolog (Drosophila)
chr19_+_47253484	2.984		Neurl1a	neuralized homolog 1A (Drosophila)
chr11_-_74710462	2.463		Sgsm2	small G protein signaling modulator 2
chr19_+_47253309	1.822	NM_021360	Neurl1a	neuralized homolog 1A (Drosophila)
chr12_+_114378688	1.612		Crip2	cysteine rich protein 2
chr8_+_18846471	1.340		Agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr8_-_13253995	1.328	NM_172750	Adprhl1	ADP-ribosylhydrolase like 1
chr9_-_21889841	1.187		Ecsit	ECSIT homolog (Drosophila)
chr1_-_164478628	0.827		Mettl13	methyltransferase like 13
chr19_+_6334978	0.743	NM_001168488 NM_001168489 NM_001168490 NM_008583	Men1	multiple endocrine neoplasia 1
chr17_+_69788665	0.651	NM_001145192	A330050F15Rik	RIKEN cDNA A330050F15 gene
chr5_+_117570113	0.648		Taok3	TAO kinase 3
chr8_+_18846524	0.300		Agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
12.50	4.27e-10	GO:0007268	synaptic transmission
10.55	9.26e-10	GO:0019226	transmission of nerve impulse
10.55	9.26e-10	GO:0035637	multicellular organismal signaling
9.16	1.69e-09	GO:0007267	cell-cell signaling
6.26	1.94e-07	GO:0007154	cell communication
17.74	9.17e-07	GO:0003001	generation of a signal involved in cell-cell signaling
17.74	9.17e-07	GO:0023061	signal release
8.96	9.61e-07	GO:0046903	secretion
22.62	1.08e-06	GO:0001505	regulation of neurotransmitter levels
10.46	3.70e-06	GO:0032940	secretion by cell
29.30	2.47e-05	GO:0007269	neurotransmitter secretion
16.53	1.03e-04	GO:0006836	neurotransmitter transport
4.01	1.94e-03	GO:0051649	establishment of localization in cell
5.86	3.68e-03	GO:0007610	behavior
3.42	6.76e-03	GO:0010646	regulation of cell communication
14.14	1.32e-02	GO:0007631	feeding behavior
3.36	1.58e-02	GO:0051641	cellular localization
46.03	1.65e-02	GO:0046329	negative regulation of JNK cascade
2.87	1.95e-02	GO:0023051	regulation of signaling
20.46	2.05e-02	GO:0048489	synaptic vesicle transport
7.27	2.41e-02	GO:0051969	regulation of transmission of nerve impulse
2.08	2.74e-02	GO:0051179	localization
3.60	2.78e-02	GO:0022008	neurogenesis
37.91	3.04e-02	GO:0070303	negative regulation of stress-activated protein kinase signaling cascade
8.72	3.14e-02	GO:0048511	rhythmic process
2.56	3.35e-02	GO:0065008	regulation of biological quality
4.09	3.56e-02	GO:0016192	vesicle-mediated transport
6.69	4.07e-02	GO:0031644	regulation of neurological system process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
8.11	6.14e-10	GO:0045202	synapse
9.04	4.30e-08	GO:0044456	synapse part
19.53	8.59e-08	GO:0008021	synaptic vesicle
6.20	5.18e-07	GO:0043005	neuron projection
13.25	2.69e-06	GO:0030136	clathrin-coated vesicle
4.09	5.79e-06	GO:0042995	cell projection
11.65	8.16e-06	GO:0030135	coated vesicle
5.57	5.61e-05	GO:0016023	cytoplasmic membrane-bounded vesicle
4.66	6.76e-05	GO:0031410	cytoplasmic vesicle
4.94	8.36e-05	GO:0030054	cell junction
5.28	1.03e-04	GO:0031988	membrane-bounded vesicle
4.38	1.46e-04	GO:0031982	vesicle
6.36	3.96e-04	GO:0044297	cell body
29.63	1.01e-03	GO:0030672	synaptic vesicle membrane
6.01	1.96e-03	GO:0043025	neuronal cell body
6.62	2.98e-03	GO:0030424	axon
13.27	3.99e-03	GO:0030426	growth cone
12.79	4.76e-03	GO:0030427	site of polarized growth
6.04	5.70e-03	GO:0030425	dendrite
1.95	7.74e-03	GO:0071944	cell periphery
15.92	1.23e-02	GO:0030665	clathrin coated vesicle membrane
1.93	1.32e-02	GO:0005886	plasma membrane
107.39	1.38e-02	GO:0032588	trans-Golgi network membrane
2.84	2.34e-02	GO:0000267	cell fraction
2.37	3.23e-02	GO:0044459	plasma membrane part
12.28	3.38e-02	GO:0030662	coated vesicle membrane
8.15	4.01e-02	GO:0033267	axon part
7.91	4.59e-02	GO:0019717	synaptosome

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
4.72	2.30e-03	GO:0005509	calcium ion binding