Motif ID: SOX17.p2

Z-value: 1.591


Transcription factors associated with SOX17.p2:

Gene SymbolEntrez IDGene Name
Sox17 20671 SRY-box containing gene 17

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox17chr1_-_4486443-0.402.3e-08Click!


Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_11482121 22.996 NM_029499
Ms4a4c
membrane-spanning 4-domains, subfamily A, member 4C
chr4_+_134024234 20.988 NM_019641
Stmn1
stathmin 1
chr17_-_51878720 18.853 Satb1
special AT-rich sequence binding protein 1
chr7_-_52622323 16.901


chr16_-_17125198 15.123 NM_183287
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr16_+_52031704 14.738 Cblb
Casitas B-lineage lymphoma b
chr9_-_70269246 14.389 Ccnb2
cyclin B2
chr11_+_68859125 13.779 NM_011496
Aurkb
aurora kinase B
chr7_-_80703275 13.592 1810026B05Rik
RIKEN cDNA 1810026B05 gene
chr1_+_34516650 13.443 Ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr6_+_124780226 12.964 Cdca3
cell division cycle associated 3
chr1_+_34516590 12.873 NM_011206
Ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr13_-_101556356 12.673 NM_172301
Ccnb1
cyclin B1
chr6_+_124780193 12.057 NM_013538
Cdca3
cell division cycle associated 3
chr8_-_13677450 11.776 NM_009025
Rasa3
RAS p21 protein activator 3
chr11_+_23156022 11.581 NM_001035226
NM_134014
Xpo1

exportin 1, CRM1 homolog (yeast)

chr3_-_107135939 11.246 NM_001045807
Rbm15
RNA binding motif protein 15
chr11_-_116274264 11.060 NM_027258
Rnf157
ring finger protein 157
chr11_+_11586215 11.049 NM_001025597
NM_009578
Ikzf1

IKAROS family zinc finger 1

chr4_-_151851624 10.832 Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr4_-_133443662 10.794 NM_009097
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr11_-_106021399 10.772 NM_172397
Limd2
LIM domain containing 2
chr9_+_83728331 10.393 Ttk
Ttk protein kinase
chr7_-_133848235 10.342 NM_009898
Coro1a
coronin, actin binding protein 1A
chr5_+_30969259 10.097 NM_007681
Cenpa
centromere protein A
chr11_-_98190774 10.080 NM_010895
Neurod2
neurogenic differentiation 2
chr16_+_52031661 9.975 NM_001033238
Cblb
Casitas B-lineage lymphoma b
chr3_+_96025040 9.938 NM_178214
Hist2h2be
histone cluster 2, H2be
chr9_+_83728295 9.887 NM_001110265
NM_009445
Ttk

Ttk protein kinase

chr6_+_29644178 9.829 NM_146173
Tspan33
tetraspanin 33
chr11_-_104330747 9.524 1700081L11Rik
RIKEN cDNA 1700081L11 gene
chr17_-_25023253 9.133 NM_011956
Nubp2
nucleotide binding protein 2
chr11_+_98769122 9.115 Cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr7_-_90883999 9.030 NM_010551
Il16
interleukin 16
chr4_-_124614072 9.005 NM_026560
Cdca8
cell division cycle associated 8
chr6_-_86619001 8.972 NM_010751
Mxd1
MAX dimerization protein 1
chr8_-_107813357 8.805 NM_001166394
NM_028888
4931428F04Rik

RIKEN cDNA 4931428F04 gene

chr7_+_13466525 8.788 NM_153802
Zfp128
zinc finger protein 128
chr2_+_144649401 8.746 NM_025490
1700010M22Rik
RIKEN cDNA 1700010M22 gene
chr14_+_56236989 8.714 NM_020002
Rec8
REC8 homolog (yeast)
chr14_-_47809063 8.681 NM_008102
Gch1
GTP cyclohydrolase 1
chr12_-_56087322 8.557 NM_013815
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr7_+_149135990 8.554 NM_001009929
NM_001009930
Brsk2

BR serine/threonine kinase 2

chr9_+_72655019 8.443 NM_175485
Prtg
protogenin homolog (Gallus gallus)
chr7_+_3332984 8.383 Cacng7
calcium channel, voltage-dependent, gamma subunit 7
chr3_+_89904315 8.064


chr2_+_146047656 8.017 NM_016889
Insm1
insulinoma-associated 1
chr9_-_70269326 7.898 NM_007630
Ccnb2
cyclin B2
chr14_+_55634290 7.880 NM_026890
Ngdn
neuroguidin, EIF4E binding protein
chr11_-_116274124 7.853 Rnf157
ring finger protein 157
chr7_-_25654709 7.838 NM_182785
Lypd4
Ly6/Plaur domain containing 4
chr11_+_98769162 7.837 NM_001025779
Cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr6_+_145070255 7.735 NM_008511
Lrmp
lymphoid-restricted membrane protein
chr4_+_134676559 7.712 NM_019732
Runx3
runt related transcription factor 3
chr19_-_15999377 7.591 NM_177420
Psat1
phosphoserine aminotransferase 1
chr19_+_37509290 7.565 NM_008245
Hhex
hematopoietically expressed homeobox
chr1_-_185857753 7.448 NM_028516
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr5_-_8622882 7.426 NM_198620
Rundc3b
RUN domain containing 3B
chr10_+_111497244 7.192 NM_027018
Glipr1l1
GLI pathogenesis-related 1 like 1
chr1_+_19093102 7.087 NM_153154
Tcfap2d
transcription factor AP-2, delta
chr11_-_114657186 7.046 NM_028055
Btbd17
BTB (POZ) domain containing 17
chr3_-_68848657 7.031 NM_025863
Trim59
tripartite motif-containing 59
chr17_-_24854956 6.939 NM_026205
Rnf151
ring finger protein 151
chr3_-_36470904 6.871 NM_009828
Ccna2
cyclin A2
chr11_-_98885428 6.858 NM_011623
Top2a
topoisomerase (DNA) II alpha
chr18_-_6516073 6.847 NM_007935
Epc1
enhancer of polycomb homolog 1 (Drosophila)
chr3_-_68848588 6.817 Trim59
tripartite motif-containing 59
chr17_+_87762817 6.799 Ttc7
tetratricopeptide repeat domain 7
chr2_-_39046224 6.798 NM_178778
Scai
suppressor of cancer cell invasion
chrX_+_90900201 6.761 NM_177546
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chrX_-_7151340 6.754 Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr7_-_139508762 6.605 NM_029935
Chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr2_+_155890933 6.600 NM_139151
Spag4
sperm associated antigen 4
chr11_+_98769464 6.576 NM_011799
Cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr2_+_3630729 6.571 NM_025626
Fam107b
family with sequence similarity 107, member B
chr10_+_53316720 6.559 NM_025541
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr3_-_36470845 6.530 Ccna2
cyclin A2
chr17_-_25864310 6.496 NM_145409
Chtf18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr16_+_91225794 6.493 NM_016967
Olig2
oligodendrocyte transcription factor 2
chr2_-_5635547 6.416 NM_177343
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr3_-_36470882 6.409 Ccna2
cyclin A2
chr3_+_9250566 6.362 NM_177660
Zbtb10
zinc finger and BTB domain containing 10
chr16_+_44765848 6.345 NM_021325
Cd200r1
CD200 receptor 1
chr1_-_167932735 6.295 NM_011137
NM_198932
Pou2f1

POU domain, class 2, transcription factor 1

chr2_+_112124767 6.274 NM_133648
Slc12a6
solute carrier family 12, member 6
chr4_+_154335029 6.271 NM_010419
Hes5
hairy and enhancer of split 5 (Drosophila)
chr3_-_105970438 6.236 NM_009892
Chi3l3
chitinase 3-like 3
chr7_+_89319717 6.231 NM_017400
Sh3gl3
SH3-domain GRB2-like 3
chr7_+_17460697 6.222 Dact3
dapper homolog 3, antagonist of beta-catenin (xenopus)
chr9_-_62644026 6.203 Fem1b
feminization 1 homolog b (C. elegans)
chr7_-_56892061 6.126 NM_001005232
Dbx1
developing brain homeobox 1
chr6_-_148894953 6.121 NM_019643
Fam60a
family with sequence similarity 60, member A
chr12_+_25393083 6.045 NM_009104
Rrm2
ribonucleotide reductase M2
chr9_+_13632152 6.030 NM_176836
Fam76b
family with sequence similarity 76, member B
chr9_+_65738150 5.902 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr10_-_94407211 5.872 NM_018797
Plxnc1
plexin C1
chr10_+_84218792 5.865 NM_001024918
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr5_-_138721164 5.848 NM_172412
Gpc2
glypican 2 (cerebroglycan)
chr9_-_103382586 5.845 NM_001002896
Bfsp2
beaded filament structural protein 2, phakinin
chr6_+_125095236 5.829 NM_178787
NM_001039669
Iffo1

intermediate filament family orphan 1

chr12_-_76697166 5.819 NM_012024
Ppp2r5e
protein phosphatase 2, regulatory subunit B (B56), epsilon isoform
chr4_-_118109775 5.817 NM_023223
Cdc20
cell division cycle 20 homolog (S. cerevisiae)
chrX_+_89735287 5.766 NM_001034103
Gm5941
predicted gene 5941
chr13_-_56236756 5.758 H2afy
H2A histone family, member Y
chr2_+_167340686 5.723 Rnf114
ring finger protein 114
chr2_+_91366966 5.722 Ckap5
cytoskeleton associated protein 5
chr3_-_83844042 5.720 NM_172681
D930015E06Rik
RIKEN cDNA D930015E06 gene
chr2_-_5635517 5.720 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr17_-_53828596 5.698 NM_028232
Sgol1
shugoshin-like 1 (S. pombe)
chr17_-_37712365 5.649 NM_146289
Olfr113
olfactory receptor 113
chr10_+_90039435 5.638 NM_001177396
NM_001177398
NM_181398
Ipw
Anks1b


imprinted gene in the Prader-Willi syndrome region
ankyrin repeat and sterile alpha motif domain containing 1B


chr11_-_49526211 5.626 NM_212484
Cnot6
CCR4-NOT transcription complex, subunit 6
chr9_-_83334633 5.622 NM_027448
NM_029434
Lca5

Leber congenital amaurosis 5 (human)

chr11_-_102786433 5.621 NM_197959
Kif18b
kinesin family member 18B
chr4_-_151851574 5.617 NM_010598
Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chrX_-_7151185 5.613 NM_138605
Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr3_+_89586320 5.600 Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr10_+_40069113 5.598 NM_001168304
NM_198164
Cdk19

cyclin-dependent kinase 19

chr11_-_102786403 5.559 Kif18b
kinesin family member 18B
chr2_+_150735306 5.551 NM_001163476
NM_027014
Gins1

GINS complex subunit 1 (Psf1 homolog)

chr10_-_80962400 5.516 S1pr4
sphingosine-1-phosphate receptor 4
chr1_-_36502079 5.515 NM_001013374
Lman2l
lectin, mannose-binding 2-like
chr7_+_148033703 5.507 NM_027019
Odf3
outer dense fiber of sperm tails 3
chr9_+_27204405 5.483 NM_029299
Spata19
spermatogenesis associated 19
chr4_+_11118500 5.475 NM_001037134
Ccne2
cyclin E2
chr7_-_140793797 5.458 NM_028654
4930404H21Rik
RIKEN cDNA 4930404H21 gene
chr2_+_118872854 5.435 NM_029617
Casc5
cancer susceptibility candidate 5
chr19_+_11518042 5.423 NM_021718
Ms4a4b
membrane-spanning 4-domains, subfamily A, member 4B
chrX_+_72341192 5.422 NM_001030307
Dkc1
dyskeratosis congenita 1, dyskerin homolog (human)
chr4_+_108132677 5.403 Zcchc11
zinc finger, CCHC domain containing 11
chr9_-_21564742 5.402 Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_-_31319977 5.373 NM_178252
Arhgap33
Rho GTPase activating protein 33
chr16_-_46120221 5.347 NM_032465
Cd96
CD96 antigen
chr9_+_118387306 5.323 NM_001164789
NM_010136
Eomes

eomesodermin homolog (Xenopus laevis)

chr7_-_139508857 5.296 Chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr2_-_5635228 5.241 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr17_-_35975148 5.234 NM_011655
Tubb5
tubulin, beta 5
chr11_+_86922732 5.225 NM_025377
Fam33a
family with sequence similarity 33, member A
chr2_+_4322020 5.205 NM_001177843
Frmd4a
FERM domain containing 4A
chr4_-_22415277 5.203 NM_008899
Pou3f2
POU domain, class 3, transcription factor 2
chr11_-_86922163 5.182 NM_175563
Prr11
proline rich 11
chr17_-_24607134 5.149 E4f1
4833447I15Rik
E4F transcription factor 1
RIKEN cDNA 4833447I15 gene
chr3_+_94964364 5.132 Sema6c
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr9_+_65738168 5.122 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr5_-_124170947 5.111 Zcchc8
zinc finger, CCHC domain containing 8
chr8_-_83262881 5.103 Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr9_-_123883223 5.098 Ccr1
chemokine (C-C motif) receptor 1
chr17_-_79754427 5.093 NM_026514
Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr5_+_114581164 5.078 NM_011677
Ung
uracil DNA glycosylase
chr13_-_56236910 5.060 NM_001159513
NM_001159514
NM_001159515
NM_012015
H2afy



H2A histone family, member Y



chr6_-_83267540 5.043 NM_008638
Mthfd2
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr11_-_75161767 5.035 NM_001164223
NM_026653
Rpa1

replication protein A1

chr10_-_80005514 5.025 Rexo1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr17_-_24388262 5.015 NM_007634
Ccnf
cyclin F
chr5_-_23536487 4.996 NM_053090
Fam126a
family with sequence similarity 126, member A
chr7_-_52622373 4.991 NM_029741
Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr17_-_79754229 4.981 Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr8_+_77633426 4.958 NM_008566
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr11_+_94828911 4.939 NM_018792
Hils1
histone H1-like protein in spermatids 1
chr7_-_15208414 4.933 NM_001039146
Vmn1r90
vomeronasal 1 receptor 90
chr5_+_28492235 4.932 NM_010134
En2
engrailed 2
chr10_+_96079634 4.924 NM_007569
Btg1
B-cell translocation gene 1, anti-proliferative
chr12_-_76697148 4.921 Ppp2r5e
protein phosphatase 2, regulatory subunit B (B56), epsilon isoform
chr17_+_36002537 4.904 NM_001146711
2310014H01Rik
RIKEN cDNA 2310014H01 gene
chr9_-_123883398 4.884 NM_009912
Ccr1
chemokine (C-C motif) receptor 1
chr15_-_79572885 4.867 NM_194342
Sun2
Sad1 and UNC84 domain containing 2
chr7_+_109614267 4.816 Rrm1
ribonucleotide reductase M1
chr9_+_78243583 4.815 NM_001191044
Ddx43
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr2_+_158492468 4.803 NM_153089
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr13_-_97440734 4.792 NM_008255
Hmgcr
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
chr7_-_52494453 4.786 Cd37
CD37 antigen
chr3_+_137527448 4.784 NM_016750
H2afz
H2A histone family, member Z
chr9_-_32348863 4.773 NM_008026
Fli1
Friend leukemia integration 1
chr5_+_114580397 4.768 NM_001040691
Ung
uracil DNA glycosylase
chr12_-_115286643 4.759 Igh-V11
immunoglobulin heavy chain (V11 family)
chr19_+_41904459 4.739 NM_008043
Frat1
frequently rearranged in advanced T-cell lymphomas
chr3_-_9833502 4.731 NM_001195031
NM_053182
Pag1

phosphoprotein associated with glycosphingolipid microdomains 1

chr3_+_89904553 4.700 Tpm3
tropomyosin 3, gamma
chr5_-_123350242 4.698 NM_013910
Kdm2b
lysine (K)-specific demethylase 2B
chr4_+_109650629 4.692 NM_172296
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr4_+_132686434 4.671 NM_153423
Wasf2
WAS protein family, member 2
chr6_+_139990045 4.665 NM_007605
Capza3
capping protein (actin filament) muscle Z-line, alpha 3
chr4_-_154417257 4.663 Plch2
phospholipase C, eta 2
chr10_+_43198945 4.651 NM_199028
Bend3
BEN domain containing 3
chr2_-_72931338 4.647


chr4_-_115796249 4.636 NM_001122958
NM_009015
NM_001122959
Rad54l


RAD54 like (S. cerevisiae)


chr2_+_92024338 4.633 NM_138755
Phf21a
PHD finger protein 21A
chr6_+_86354212 4.631 NM_001164078
NM_001164079
NM_011585
Tia1


cytotoxic granule-associated RNA binding protein 1


chr17_-_33897428 4.624 NM_008997
Rab11b
RAB11B, member RAS oncogene family
chr12_-_76697214 4.592 Ppp2r5e
protein phosphatase 2, regulatory subunit B (B56), epsilon isoform
chr1_+_193645351 4.588 NM_010892
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr5_-_100467945 4.549 Hnrpdl
heterogeneous nuclear ribonucleoprotein D-like
chr11_-_119948078 4.537 Azi1
5-azacytidine induced gene 1
chr13_-_41165827 4.536 NM_008547
Mak
male germ cell-associated kinase
chr4_-_154041819 4.533 NM_028513
Actrt2
actin-related protein T2
chr7_+_97357406 4.520 Picalm
phosphatidylinositol binding clathrin assembly protein
chr7_-_52622289 4.519 Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr16_-_50591201 4.505 NM_027046
Ccdc54
coiled-coil domain containing 54
chr10_-_122550401 4.493 Usp15
ubiquitin specific peptidase 15
chr4_+_120204835 4.492 NM_177570
Slfnl1
schlafen like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.59 2.03e-24 GO:0090304 nucleic acid metabolic process
1.58 3.16e-23 GO:0010468 regulation of gene expression
1.59 1.15e-22 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.58 1.72e-22 GO:0010556 regulation of macromolecule biosynthetic process
1.61 2.39e-22 GO:0051252 regulation of RNA metabolic process
1.62 2.53e-22 GO:0016070 RNA metabolic process
1.50 2.65e-21 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54 1.08e-20 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 1.71e-20 GO:0006355 regulation of transcription, DNA-dependent
1.45 2.16e-20 GO:0006807 nitrogen compound metabolic process
1.54 2.52e-20 GO:0031326 regulation of cellular biosynthetic process
1.45 3.49e-20 GO:0034641 cellular nitrogen compound metabolic process
1.53 5.84e-20 GO:0051171 regulation of nitrogen compound metabolic process
1.69 1.02e-19 GO:0006351 transcription, DNA-dependent
1.52 1.21e-19 GO:0009889 regulation of biosynthetic process
1.69 1.40e-19 GO:0032774 RNA biosynthetic process
1.45 3.11e-19 GO:0060255 regulation of macromolecule metabolic process
1.52 6.91e-18 GO:0010467 gene expression
1.36 8.58e-18 GO:0044260 cellular macromolecule metabolic process
1.52 3.78e-16 GO:0034645 cellular macromolecule biosynthetic process
1.51 5.57e-16 GO:0009059 macromolecule biosynthetic process
1.40 1.54e-15 GO:0031323 regulation of cellular metabolic process
1.40 2.25e-15 GO:0080090 regulation of primary metabolic process
1.31 2.73e-15 GO:0043170 macromolecule metabolic process
1.35 9.42e-14 GO:0019222 regulation of metabolic process
1.23 1.82e-11 GO:0044238 primary metabolic process
1.38 3.52e-11 GO:0044249 cellular biosynthetic process
1.36 1.95e-10 GO:0032502 developmental process
1.36 2.69e-10 GO:0009058 biosynthetic process
1.22 9.49e-10 GO:0044237 cellular metabolic process
1.34 3.20e-08 GO:0007275 multicellular organismal development
1.35 5.67e-08 GO:0048856 anatomical structure development
1.42 9.33e-08 GO:0030154 cell differentiation
1.41 1.29e-07 GO:0048869 cellular developmental process
1.35 1.47e-06 GO:0048519 negative regulation of biological process
1.70 1.93e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.70 2.14e-06 GO:0010629 negative regulation of gene expression
1.52 2.39e-06 GO:0007399 nervous system development
1.67 4.00e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
1.64 1.01e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.35 1.48e-05 GO:0048523 negative regulation of cellular process
1.16 1.49e-05 GO:0008152 metabolic process
1.65 2.24e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61 2.60e-05 GO:0009890 negative regulation of biosynthetic process
2.07 2.92e-05 GO:0007283 spermatogenesis
2.07 2.92e-05 GO:0048232 male gamete generation
1.64 3.08e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.32 3.18e-05 GO:0048731 system development
1.68 3.46e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.52 4.58e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.49 7.84e-05 GO:0009892 negative regulation of metabolic process
1.66 8.35e-05 GO:0051253 negative regulation of RNA metabolic process
1.88 1.23e-04 GO:0007276 gamete generation
2.13 1.38e-04 GO:0030900 forebrain development
1.54 3.41e-04 GO:0022008 neurogenesis
1.31 3.87e-04 GO:0071842 cellular component organization at cellular level
1.69 5.59e-04 GO:0051276 chromosome organization
1.47 7.43e-04 GO:0031324 negative regulation of cellular metabolic process
1.84 8.00e-04 GO:0007420 brain development
1.38 8.25e-04 GO:0006996 organelle organization
1.49 1.01e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.47 1.14e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.29 1.17e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.80 2.15e-03 GO:0000279 M phase
1.71 2.48e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.51 2.75e-03 GO:0048699 generation of neurons
1.69 3.03e-03 GO:0007417 central nervous system development
1.70 3.73e-03 GO:0019953 sexual reproduction
1.95 5.19e-03 GO:0048285 organelle fission
1.44 5.40e-03 GO:0009891 positive regulation of biosynthetic process
1.47 5.67e-03 GO:0048468 cell development
1.48 5.74e-03 GO:0007049 cell cycle
1.44 6.74e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.94 6.87e-03 GO:0000087 M phase of mitotic cell cycle
1.64 7.15e-03 GO:0032504 multicellular organism reproduction
1.64 7.15e-03 GO:0048609 multicellular organismal reproductive process
1.95 7.92e-03 GO:0000280 nuclear division
1.95 7.92e-03 GO:0007067 mitosis
1.59 8.43e-03 GO:0030182 neuron differentiation
1.46 9.29e-03 GO:0010628 positive regulation of gene expression
1.30 1.05e-02 GO:0048513 organ development
1.44 1.34e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 1.34e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.69 1.56e-02 GO:0007389 pattern specification process
1.74 1.78e-02 GO:0016568 chromatin modification
1.70 2.60e-02 GO:0002520 immune system development
1.63 2.75e-02 GO:0022403 cell cycle phase
1.46 2.90e-02 GO:0051254 positive regulation of RNA metabolic process
1.45 3.58e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.66 4.01e-02 GO:0006325 chromatin organization
2.05 4.67e-02 GO:0006260 DNA replication

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.44 8.93e-32 GO:0005634 nucleus
1.18 1.51e-13 GO:0043229 intracellular organelle
1.18 2.13e-13 GO:0043226 organelle
1.14 4.07e-12 GO:0005622 intracellular
1.15 4.47e-12 GO:0044424 intracellular part
1.51 1.71e-11 GO:0044428 nuclear part
1.18 2.08e-11 GO:0043231 intracellular membrane-bounded organelle
1.18 2.83e-11 GO:0043227 membrane-bounded organelle
1.54 2.19e-10 GO:0031981 nuclear lumen
1.56 2.51e-07 GO:0005654 nucleoplasm
1.41 6.63e-07 GO:0031974 membrane-enclosed lumen
1.41 6.77e-07 GO:0070013 intracellular organelle lumen
1.41 8.15e-07 GO:0043233 organelle lumen
1.71 1.09e-04 GO:0005694 chromosome
1.28 1.76e-04 GO:0043228 non-membrane-bounded organelle
1.28 1.76e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.73 1.80e-04 GO:0044427 chromosomal part
2.06 1.92e-04 GO:0000228 nuclear chromosome
1.56 2.08e-04 GO:0044451 nucleoplasm part
1.61 2.83e-04 GO:0015630 microtubule cytoskeleton
2.03 1.91e-03 GO:0044454 nuclear chromosome part
1.18 3.20e-03 GO:0044446 intracellular organelle part
1.17 3.59e-03 GO:0044422 organelle part
2.15 5.05e-03 GO:0000775 chromosome, centromeric region
1.29 2.55e-02 GO:0005856 cytoskeleton
1.17 4.90e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.52 6.81e-19 GO:0003676 nucleic acid binding
1.61 1.37e-16 GO:0003677 DNA binding
1.79 6.36e-13 GO:0030528 transcription regulator activity
1.85 2.54e-12 GO:0001071 nucleic acid binding transcription factor activity
1.85 2.54e-12 GO:0003700 sequence-specific DNA binding transcription factor activity
1.15 8.29e-12 GO:0005488 binding
1.55 1.43e-09 GO:0008270 zinc ion binding
1.45 4.99e-08 GO:0046914 transition metal ion binding
1.71 4.22e-07 GO:0043565 sequence-specific DNA binding
1.99 3.53e-06 GO:0016564 transcription repressor activity
1.15 1.17e-03 GO:0005515 protein binding
1.27 2.08e-03 GO:0000166 nucleotide binding
1.20 2.81e-03 GO:0046872 metal ion binding
1.20 3.05e-03 GO:0043167 ion binding
1.20 3.47e-03 GO:0043169 cation binding
1.85 2.64e-02 GO:0003682 chromatin binding
1.29 3.74e-02 GO:0005524 ATP binding