Motif ID: T.p2

Z-value: 0.789


Transcription factors associated with T.p2:

Gene SymbolEntrez IDGene Name
T 20997 brachyury

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tchr17_+_8627287-0.249.6e-04Click!


Activity profile for motif T.p2.

activity profile for motif T.p2


Sorted Z-values histogram for motif T.p2

Sorted Z-values for motif T.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of T.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_20676453 16.693 NM_013467
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr15_+_12082671 12.584 Zfr
zinc finger RNA binding protein
chr7_-_107805466 12.225 NM_001163186
NM_001163187
Plekhb1

pleckstrin homology domain containing, family B (evectins) member 1

chr10_-_61738537 11.347 Hk1
hexokinase 1
chr8_+_46970860 9.873 Pdlim3
PDZ and LIM domain 3
chr8_+_46970814 9.862 NM_016798
Pdlim3
PDZ and LIM domain 3
chr15_-_101681183 9.372 NM_008473
Krt1
keratin 1
chr15_-_81191176 9.252 NM_011399
Slc25a17
solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
chr15_-_12522310 9.018 NM_001081064
Pdzd2
PDZ domain containing 2
chr19_+_23240506 6.947 Klf9
Kruppel-like factor 9
chr12_+_110783593 6.694 Meg3
maternally expressed 3
chr11_-_55208276 6.677


chrX_-_147091911 6.634 NM_001002272
NM_019548
Tro

trophinin

chr5_-_143668369 6.597 Actb
actin, beta
chr7_-_107806887 6.433 NM_001163183
NM_001163184
NM_001163185
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr8_-_126957835 6.401 NM_171824
Pgbd5
piggyBac transposable element derived 5
chr12_+_110806715 5.950 Meg3
maternally expressed 3
chr3_-_107820766 5.944 NM_010358
Gstm1
glutathione S-transferase, mu 1
chr2_-_25079684 5.609 Tubb2c
tubulin, beta 2C
chr7_-_4498168 5.254 NM_016908
Syt5
synaptotagmin V
chr6_-_24905939 5.167 NM_177013
Tmem229a
transmembrane protein 229A
chr4_-_82151657 5.124 Nfib
nuclear factor I/B
chr7_-_25772525 5.074 Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr12_+_110783786 4.871 Meg3
maternally expressed 3
chr3_+_67696141 4.777 NM_001113419
NM_177585
Iqcj-schip1
Iqcj
IQ motif containing J-schwannomin interacting protein 1 read-through transcript
IQ motif containing J
chr7_-_6683113 4.768 NM_008817
Peg3
paternally expressed 3
chr5_+_91201521 4.748 Pf4
platelet factor 4
chr10_-_24919916 4.583 Akap7
A kinase (PRKA) anchor protein 7
chr11_-_100599413 4.582 NM_024456
Rab5c
RAB5C, member RAS oncogene family
chr6_-_94650118 4.470 NM_008377
Lrig1
leucine-rich repeats and immunoglobulin-like domains 1
chr7_-_82453166 4.172 Sv2b
synaptic vesicle glycoprotein 2 b
chrX_+_133200982 4.097 Tceal3
transcription elongation factor A (SII)-like 3
chr4_-_75779379 3.940 NM_001014288
Ptprd
protein tyrosine phosphatase, receptor type, D
chr5_-_143668403 3.721 Actb
actin, beta
chr5_+_91201538 3.673 Pf4
platelet factor 4
chr14_+_70857227 3.458 NM_145981
Phyhip
phytanoyl-CoA hydroxylase interacting protein
chr15_-_75950624 3.432 NM_144848
Eppk1
BC024139
epiplakin 1
cDNA sequence BC024139
chr14_+_21527175 3.427 2310021P13Rik
RIKEN cDNA 2310021P13 gene
chrX_-_97821244 3.410 NM_028303
Pdzd11
PDZ domain containing 11
chr2_-_119916315 3.379 Ehd4
EH-domain containing 4
chr4_+_148913978 3.366 Ctnnbip1
catenin beta interacting protein 1
chr9_+_53698053 3.292 NM_025540
Sln
sarcolipin
chr1_-_75250520 3.278 Ptprn
protein tyrosine phosphatase, receptor type, N
chr1_+_90003410 3.271 Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr9_-_45012097 3.205 NM_145403
Tmprss4
transmembrane protease, serine 4
chr12_+_71008808 3.179 Atl1
atlastin GTPase 1
chr15_-_75901305 3.158 Puf60
poly-U binding splicing factor 60
chr15_-_101700048 3.134 NM_001003667
Krt77
keratin 77
chr5_+_73797316 3.118 NM_181323
Cwh43
cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
chr5_-_143668398 3.084 NM_007393
Actb
actin, beta
chr7_-_4474044 3.077 NM_009406
Tnni3
troponin I, cardiac 3
chr16_-_5222390 2.996 NM_001033220
AU021092
expressed sequence AU021092
chr5_-_124028994 2.963 Clip1
CAP-GLY domain containing linker protein 1
chr4_-_82151590 2.940 Nfib
nuclear factor I/B
chr9_+_15043658 2.911 2200002K05Rik
RIKEN cDNA 2200002K05 gene
chr19_+_34175422 2.902 NM_023903
Lipm
lipase, family member M
chr18_-_36886375 2.861 Cd14
CD14 antigen
chr19_-_6982516 2.771 Prdx5
peroxiredoxin 5
chr16_-_5222354 2.733 AU021092
expressed sequence AU021092
chr2_+_164388211 2.728 NM_026323
Wfdc2
WAP four-disulfide core domain 2
chr7_-_147298872 2.642 Echs1
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
chr10_+_96942124 2.599 NM_001190451
Dcn
decorin
chr12_-_4344470 2.594 Ncoa1
nuclear receptor coactivator 1
chr11_-_11832366 2.582 Grb10
growth factor receptor bound protein 10
chr17_+_35204268 2.580 NM_023463
Ly6g6c
lymphocyte antigen 6 complex, locus G6C
chr8_+_47576483 2.556 Acsl1
acyl-CoA synthetase long-chain family member 1
chr4_+_53453302 2.526 Slc44a1
solute carrier family 44, member 1
chr9_-_95745663 2.525 NM_001033210
Pls1
plastin 1 (I-isoform)
chr3_+_94497485 2.439 NM_019414
Selenbp2
selenium binding protein 2
chr7_-_51920870 2.373 NM_028021
Myh14
myosin, heavy polypeptide 14
chr2_+_143768541 2.356 Dstn
destrin
chr4_-_76240202 2.347 NM_011211
Ptprd
protein tyrosine phosphatase, receptor type, D
chr2_+_121134843 2.337 Mtap1a
microtubule-associated protein 1 A
chr18_-_36886307 2.280 NM_009841
Cd14
CD14 antigen
chr10_+_21698470 2.252 NM_001161847
Sgk1
serum/glucocorticoid regulated kinase 1
chr2_+_109514856 2.233 NM_007540
Bdnf
brain derived neurotrophic factor
chr15_-_89256262 2.232 NM_009948
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr1_-_166368439 2.167 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr8_+_74092759 2.148 Slc27a1
solute carrier family 27 (fatty acid transporter), member 1
chr1_-_36756687 2.136 Actr1b
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr5_-_9725158 2.117 Grm3
glutamate receptor, metabotropic 3
chr6_+_22825464 2.063 NM_001081306
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chrX_+_133200913 2.052 NM_001029978
Tceal3
transcription elongation factor A (SII)-like 3
chr11_-_105805442 2.050 NM_007805
Cyb561
cytochrome b-561
chr5_-_51848420 2.019 Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr10_+_56097078 1.981 NM_010288
Gja1
gap junction protein, alpha 1
chr8_+_74092790 1.968 NM_011977
Slc27a1
solute carrier family 27 (fatty acid transporter), member 1
chr15_-_89256252 1.945 Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr19_-_59018112 1.929 Hspa12a
heat shock protein 12A
chr19_-_10379342 1.844 Dagla
diacylglycerol lipase, alpha
chr9_+_15043488 1.827 NM_026955
2200002K05Rik
RIKEN cDNA 2200002K05 gene
chr9_+_50302624 1.820 NM_029639
1600029D21Rik
RIKEN cDNA 1600029D21 gene
chr3_-_105746659 1.810 Atp5f1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1
chr16_+_62814501 1.810 NM_026588
Stx19
syntaxin 19
chr2_+_135567565 1.804 NM_013829
Plcb4
phospholipase C, beta 4
chr14_+_80400057 1.796 NM_001030294
Olfm4
olfactomedin 4
chr11_-_83881811 1.794 NM_019819
Dusp14
dual specificity phosphatase 14
chr11_-_70135960 1.779 NM_145684
Alox12e
arachidonate lipoxygenase, epidermal
chr18_+_38456315 1.767 Rnf14
ring finger protein 14
chr17_-_90436488 1.759 Nrxn1
neurexin I
chr1_+_151947225 1.748 NM_011198
Ptgs2
prostaglandin-endoperoxide synthase 2
chr3_-_107820705 1.720 Gstm1
glutathione S-transferase, mu 1
chr9_-_14916551 1.689 NM_001164797
Hephl1
hephaestin-like 1
chr19_-_10379361 1.680 NM_198114
Dagla
diacylglycerol lipase, alpha
chr11_-_106163120 1.677 NM_008117
Gh
growth hormone
chr11_-_59025422 1.630 Arf1
ADP-ribosylation factor 1
chr7_-_31911733 1.625 Scn1b
sodium channel, voltage-gated, type I, beta
chr11_-_69499014 1.613 NM_001159505
NM_023517
Tnfsf13

tumor necrosis factor (ligand) superfamily, member 13

chr2_+_138104219 1.591 NM_145534
Btbd3
BTB (POZ) domain containing 3
chr10_+_115614313 1.580 NM_001161839
NM_001161838
NM_001161840
Ptprr


protein tyrosine phosphatase, receptor type, R


chr7_+_17334480 1.533 Ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr11_+_28753190 1.452 NM_146015
Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr11_-_83880574 1.439 Dusp14
dual specificity phosphatase 14
chr3_+_37538808 1.423 NM_011896
Spry1
sprouty homolog 1 (Drosophila)
chr2_-_80421054 1.397 NM_016965
Nckap1
NCK-associated protein 1
chr6_+_57653067 1.393 Lancl2
LanC (bacterial lantibiotic synthetase component C)-like 2
chr1_+_74283325 1.369 Arpc2
actin related protein 2/3 complex, subunit 2
chr17_-_24306262 1.354 NM_009729
Atp6v0c-ps2
Atp6v0c
ATPase, H+ transporting, lysosomal V0 subunit C, pseudogene 2
ATPase, H+ transporting, lysosomal V0 subunit C
chrX_+_38754480 1.347 NM_016886
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr3_-_97628441 1.308 NM_001110163
Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr11_-_99982369 1.301 Krt13
keratin 13
chr13_-_74480876 1.273 Sdha
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr1_+_90034940 1.238 Ugt1a6a
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr14_+_32064648 1.238 NM_027088
Bap1
Brca1 associated protein 1
chr3_-_92655207 1.233 NM_028628
Lce1l
late cornified envelope 1L
chr3_-_105746740 1.231 Atp5f1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1
chr2_+_25312352 1.224 Clic3
chloride intracellular channel 3
chr1_-_164816645 1.220 Fmo2
flavin containing monooxygenase 2
chr11_-_94254221 1.219 NM_029600
Abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr2_+_160706405 1.219 NM_022883
Lpin3
lipin 3
chr9_-_99610481 1.190 NM_001194922
NM_019815
Cldn18

claudin 18

chr18_+_45719464 1.169 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr5_-_144266956 1.165


chr11_+_68933954 1.157 NM_033041
Hes7
hairy and enhancer of split 7 (Drosophila)
chr4_+_12833983 1.144 NM_001171801
NM_173746
Gm11818

predicted gene 11818

chr14_-_66539632 1.141 Scara3
scavenger receptor class A, member 3
chr2_-_164008333 1.129 NM_145369
Wfdc5
WAP four-disulfide core domain 5
chr18_+_38456280 1.108 NM_001164622
NM_020012
Rnf14

ring finger protein 14

chr18_+_38456364 1.105 NM_001164621
Rnf14
ring finger protein 14
chr8_+_11834520 1.103 Arhgef7
Rho guanine nucleotide exchange factor (GEF7)
chr10_+_87922331 1.101 NM_011517
Sycp3
synaptonemal complex protein 3
chr2_+_28368603 1.098 NM_001145834
NM_009058
Ralgds

ral guanine nucleotide dissociation stimulator

chrX_+_130829763 1.096 NM_026239
Tmem35
transmembrane protein 35
chr5_-_23897960 1.085 NM_001002897
Atg9b
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr10_+_98453513 1.080 Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr15_-_83002561 1.077 Cyb5r3
cytochrome b5 reductase 3
chr18_-_39078304 1.070 NM_010197
Fgf1
fibroblast growth factor 1
chr18_-_36886051 1.064 Cd14
CD14 antigen
chr14_-_100548982 1.061 NM_010636
Klf12
Kruppel-like factor 12
chr16_+_94664089 1.057 Ttc3
tetratricopeptide repeat domain 3
chr8_+_131238027 1.054 Itgb1
integrin beta 1 (fibronectin receptor beta)
chrX_-_130432840 1.045 NM_019656
Tspan6
tetraspanin 6
chr14_+_55502261 1.044 NM_007537
Bcl2l2
BCL2-like 2
chrX_+_97925185 1.043 NM_023608
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr2_-_6110280 1.019 Echdc3
enoyl Coenzyme A hydratase domain containing 3
chr7_+_150293158 0.997 NM_008434
Kcnq1
potassium voltage-gated channel, subfamily Q, member 1
chr7_-_4116102 0.991 Cdc42ep5
CDC42 effector protein (Rho GTPase binding) 5
chr19_-_5844533 0.988 Neat1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr8_+_24145593 0.977 Ank1
ankyrin 1, erythroid
chr3_-_89083562 0.971 NM_010107
Efna1
ephrin A1
chr5_-_31395853 0.965 NM_011773
Slc30a3
solute carrier family 30 (zinc transporter), member 3
chr9_+_54442900 0.963 Idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
chr15_-_75397601 0.939 NM_011837
Ly6h
lymphocyte antigen 6 complex, locus H
chr2_+_143741243 0.938 Dstn
destrin
chr7_-_4473916 0.936 Tnni3
troponin I, cardiac 3
chr2_-_66278870 0.935 NM_018733
Scn1a
sodium channel, voltage-gated, type I, alpha
chr9_-_108469265 0.933 Ndufaf3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr14_+_55502200 0.904 Bcl2l2
BCL2-like 2
chr3_-_92819586 0.897 NM_028798
Crct1
cysteine-rich C-terminal 1
chr2_+_3035629 0.873 NM_001081161
Fam171a1
family with sequence similarity 171, member A1
chr9_+_107483009 0.863 Nat6
N-acetyltransferase 6
chr5_-_109027924 0.859 Gak
cyclin G associated kinase
chr10_+_94039007 0.859 NM_177026
Tmcc3
transmembrane and coiled coil domains 3
chr6_-_139989932 0.845 NM_054066
Plcz1
phospholipase C, zeta 1
chr3_+_51028714 0.841 Ccrn4l
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr5_+_114222723 0.836 NM_025526
Iscu
IscU iron-sulfur cluster scaffold homolog (E. coli)
chr7_-_139749889 0.836


chr2_-_110203298 0.832 Fibin
fin bud initiation factor homolog (zebrafish)
chrX_+_162782484 0.815 NM_001177955
NM_001177956
NM_001177957
NM_001177958
NM_001177959
NM_001177960
Gpm6b





glycoprotein m6b





chr2_-_12933305 0.810 C1ql3
C1q-like 3
chr6_+_114081227 0.787 NM_172890
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chrX_+_38754568 0.767 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr4_-_155574875 0.764 NM_015783
Isg15
ISG15 ubiquitin-like modifier
chr15_-_83002612 0.745 Cyb5r3
cytochrome b5 reductase 3
chr2_-_110203264 0.742 Fibin
fin bud initiation factor homolog (zebrafish)
chr18_-_12464213 0.741 NM_001190371
Ankrd29
ankyrin repeat domain 29
chr3_-_88307198 0.736 Lmna
lamin A
chr6_+_56828743 0.732 Fkbp9
FK506 binding protein 9
chr2_+_25312358 0.732 NM_027085
Clic3
chloride intracellular channel 3
chr11_+_66984528 0.720 NM_001039545
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr19_-_6982094 0.719 Prdx5
peroxiredoxin 5
chr2_+_3035692 0.715 Fam171a1
family with sequence similarity 171, member A1
chr10_+_79608206 0.714


chr14_+_32064678 0.714 Bap1
Brca1 associated protein 1
chr3_-_10208480 0.708 Fabp4
Fabp9
fatty acid binding protein 4, adipocyte
fatty acid binding protein 9, testis
chr6_-_13789847 0.707 NM_145066
Gpr85
G protein-coupled receptor 85
chr1_+_169528706 0.691 Rxrg
retinoid X receptor gamma
chr6_+_7505070 0.674 NM_009311
Tac1
tachykinin 1
chr2_-_32136262 0.672


chr11_+_93905557 0.665 Spag9
sperm associated antigen 9

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.81 1.95e-03 GO:0006810 transport
1.78 3.38e-03 GO:0051234 establishment of localization
4.75 2.16e-02 GO:0051493 regulation of cytoskeleton organization
1.63 2.62e-02 GO:0051179 localization
3.11 3.79e-02 GO:0007267 cell-cell signaling

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.62 9.17e-07 GO:0044444 cytoplasmic part
1.42 8.80e-06 GO:0005737 cytoplasm
2.70 4.58e-05 GO:0005626 insoluble fraction
2.43 7.08e-05 GO:0000267 cell fraction
3.34 9.94e-05 GO:0016023 cytoplasmic membrane-bounded vesicle
2.84 2.35e-04 GO:0031410 cytoplasmic vesicle
2.77 2.42e-04 GO:0031982 vesicle
3.17 2.53e-04 GO:0031988 membrane-bounded vesicle
2.57 4.66e-04 GO:0005624 membrane fraction
1.26 1.49e-03 GO:0044424 intracellular part
1.23 6.91e-03 GO:0005622 intracellular
1.97 9.94e-03 GO:0005829 cytosol
2.08 2.50e-02 GO:0042995 cell projection
2.01 2.75e-02 GO:0031090 organelle membrane
3.84 3.15e-02 GO:0030141 stored secretory granule

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
22.77 4.33e-04 GO:0005246 calcium channel regulator activity
8.25 2.02e-02 GO:0016247 channel regulator activity
72.87 4.53e-02 GO:0031386 protein tag