Motif ID: TEAD1.p2

Z-value: 4.292


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
Tead1 21676 TEA domain family member 1
Tead2 21677 TEA domain family member 2
Tead3 21678 TEA domain family member 3
Tead4 21679 TEA domain family member 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead1chr7_+_1198228310.897.1e-63Click!
Tead2chr7_+_524711220.531.4e-14Click!
Tead3chr17_-_284875440.423.8e-09Click!
Tead4chr6_-_1282508250.371.9e-07Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_24315247 246.453 NM_010217
 Ctgf
connective tissue growth factor
chr19_-_34329804 149.834 NM_007392
 Acta2
actin, alpha 2, smooth muscle, aorta
chr7_-_34918076 110.877 NM_207212
 Wtip
WT1-interacting protein
chr9_+_102620058 98.651 Amotl2
angiomotin-like 2
chr9_+_102620051 96.685 Amotl2
angiomotin-like 2
chr9_+_102620096 93.251 NM_019764
 Amotl2
angiomotin-like 2
chr11_-_55233354 90.836 Sparc
secreted acidic cysteine rich glycoprotein
chr2_+_156601175 87.579 NM_172118
 Myl9
myosin, light polypeptide 9, regulatory
chr2_+_156601150 86.792 Myl9
myosin, light polypeptide 9, regulatory
chr1_-_45559904 82.987 Col5a2
collagen, type V, alpha 2
chr1_+_51346086 74.629 Sdpr
serum deprivation response
chr6_+_17256383 74.130 Cav1
caveolin 1, caveolae protein
chr6_+_17256369 73.479 NM_007616
 Cav1
caveolin 1, caveolae protein
chr1_+_51345952 72.733 NM_138741
 Sdpr
serum deprivation response
chr9_-_66896961 66.899 Tpm1
tropomyosin 1, alpha
chr11_-_55233581 66.759 NM_009242
 Sparc
secreted acidic cysteine rich glycoprotein
chr7_+_137789668 66.588 Tacc2
transforming, acidic coiled-coil containing protein 2
chr11_-_32122236 64.618 Rhbdf1
rhomboid family 1 (Drosophila)
chr11_-_32122259 63.525 NM_010117
 Rhbdf1
rhomboid family 1 (Drosophila)
chr11_-_55233366 63.387 Sparc
secreted acidic cysteine rich glycoprotein

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 101 entries
Enrichment   P-value GO Accession GO Term
8.49 1.25e-03 GO:0007044 cell-substrate junction assembly
6.70 9.85e-04 GO:0034329 cell junction assembly
6.42 1.60e-02 GO:0007266 Rho protein signal transduction
5.93 1.42e-04 GO:0034330 cell junction organization
5.72 4.31e-02 GO:0010594 regulation of endothelial cell migration
4.87 2.68e-02 GO:0055002 striated muscle cell development
4.65 2.58e-04 GO:0006936 muscle contraction
4.28 4.01e-04 GO:0003012 muscle system process
4.27 2.01e-02 GO:0031589 cell-substrate adhesion
4.01 2.24e-03 GO:0003007 heart morphogenesis
3.90 6.68e-03 GO:0030198 extracellular matrix organization
3.40 5.99e-05 GO:0030029 actin filament-based process
3.32 3.09e-04 GO:0001558 regulation of cell growth
3.29 3.35e-02 GO:0042692 muscle cell differentiation
3.27 1.21e-02 GO:0010975 regulation of neuron projection development
3.25 2.50e-03 GO:0031344 regulation of cell projection organization
3.23 4.33e-02 GO:0045926 negative regulation of growth
3.19 1.69e-02 GO:0043062 extracellular structure organization
3.18 4.19e-04 GO:0048514 blood vessel morphogenesis
3.12 4.68e-05 GO:0001568 blood vessel development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 42 entries
Enrichment   P-value GO Accession GO Term
8.64 4.70e-07 GO:0032432 actin filament bundle
8.56 2.27e-06 GO:0001725 stress fiber
7.63 9.58e-06 GO:0042641 actomyosin
4.50 2.83e-05 GO:0044420 extracellular matrix part
4.26 1.45e-03 GO:0016327 apicolateral plasma membrane
4.04 5.67e-03 GO:0043296 apical junction complex
3.90 4.18e-03 GO:0044449 contractile fiber part
3.81 2.13e-02 GO:0030017 sarcomere
3.77 1.59e-03 GO:0043292 contractile fiber
3.54 5.25e-08 GO:0015629 actin cytoskeleton
3.33 4.37e-02 GO:0030016 myofibril
3.19 4.07e-06 GO:0005578 proteinaceous extracellular matrix
3.17 4.19e-02 GO:0005912 adherens junction
3.11 3.07e-02 GO:0070161 anchoring junction
2.99 7.10e-06 GO:0031012 extracellular matrix
2.96 7.86e-03 GO:0016324 apical plasma membrane
2.94 1.27e-03 GO:0005911 cell-cell junction
2.92 5.29e-04 GO:0045177 apical part of cell
2.45 1.13e-02 GO:0048471 perinuclear region of cytoplasm
2.28 1.77e-08 GO:0044421 extracellular region part

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
9.74 1.72e-03 GO:0001968 fibronectin binding
4.01 4.10e-03 GO:0008201 heparin binding
3.90 5.76e-03 GO:0019838 growth factor binding
3.87 3.91e-04 GO:0005539 glycosaminoglycan binding
3.85 1.08e-04 GO:0001871 pattern binding
3.85 1.08e-04 GO:0030247 polysaccharide binding
2.63 2.13e-03 GO:0003779 actin binding
2.48 1.96e-05 GO:0008092 cytoskeletal protein binding
2.31 1.57e-02 GO:0032403 protein complex binding
2.10 1.08e-02 GO:0005509 calcium ion binding
1.80 3.31e-02 GO:0042802 identical protein binding
1.69 3.08e-02 GO:0005102 receptor binding
1.52 1.68e-13 GO:0005515 protein binding
1.25 1.58e-09 GO:0005488 binding