• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: TFAP2B.p2

Z-value: 1.363

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_28061156	32.911	NM_001038612 NM_019498	Olfm1	olfactomedin 1
chr11_+_77306825	18.693	NM_001004144	Git1	G protein-coupled receptor kinase-interactor 1
chr9_-_107134182	18.479	NM_153413	Dock3	dedicator of cyto-kinesis 3
chr5_+_88994386	16.070		Rufy3	RUN and FYVE domain containing 3
chr8_-_126957835	14.783	NM_171824	Pgbd5	piggyBac transposable element derived 5
chr19_-_5098486	14.215		Cnih2	cornichon homolog 2 (Drosophila)
chr6_+_117961386	13.672		Rasgef1a	RasGEF domain family, member 1A
chr4_+_129662284	13.625	NM_173071	Bai2	brain-specific angiogenesis inhibitor 2
chr5_-_5380077	12.546	NM_011074	Cdk14	cyclin-dependent kinase 14
chr1_-_134287712	12.354	NM_178874	Tmcc2	transmembrane and coiled-coil domains 2
chr5_+_34339258	12.117		Nat8l	N-acetyltransferase 8-like
chr2_-_165060352	11.707		Cdh22	cadherin 22
chr14_-_13655558	11.518		Cadps	Ca2+-dependent secretion activator
chr17_+_69506165	11.033		Epb4.1l3	erythrocyte protein band 4.1-like 3
chr19_-_5098381	11.028	NM_009920	Cnih2	cornichon homolog 2 (Drosophila)
chr1_+_63319842	10.913	NM_028673	Zdbf2	zinc finger, DBF-type containing 2
chr10_-_115910578	10.865	NM_021452	Kcnmb4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr5_+_34339351	10.674		Nat8l	N-acetyltransferase 8-like
chr16_-_18629938	10.670	NM_213614	Sept5	septin 5
chr12_+_109792949	10.410		Evl	Ena-vasodilator stimulated phosphoprotein
chr12_-_101758964	10.387	NM_001033213	Ttc7b	tetratricopeptide repeat domain 7B
chr5_+_37259906	10.157		Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr4_+_129662110	10.139		Bai2	brain-specific angiogenesis inhibitor 2
chr13_-_69138229	10.019		Adcy2	adenylate cyclase 2
chr17_+_24625709	10.017	NM_027937	Caskin1	CASK interacting protein 1
chr3_-_138738020	9.948		Rap1gds1	RAP1, GTP-GDP dissociation stimulator 1
chr11_+_83223154	9.679		Rasl10b	RAS-like, family 10, member B
chr1_-_33964439	9.611	NM_177235	Bend6	BEN domain containing 6
chr10_-_80945379	9.556		Celf5	CUGBP, Elav-like family member 5
chr9_-_75458865	9.528		Tmod2	tropomodulin 2
chr4_+_126846429	9.523	NM_198618	Dlgap3	discs, large (Drosophila) homolog-associated protein 3
chr14_-_13655592	9.432	NM_001042617 NM_012061	Cadps	Ca2+-dependent secretion activator
chr15_-_79635156	9.396		Nptxr	neuronal pentraxin receptor
chr9_-_75459046	9.378		Tmod2	tropomodulin 2
chr5_+_108796754	9.302		Gm10419	predicted gene 10419
chr2_+_129418930	9.157	NM_001177647 NM_007547	Sirpa	signal-regulatory protein alpha
chr15_+_30102306	9.079	NM_008729	Ctnnd2	catenin (cadherin associated protein), delta 2
chr15_-_79635138	9.066	NM_030689	Nptxr	neuronal pentraxin receptor
chr3_-_138738059	9.063		Rap1gds1	RAP1, GTP-GDP dissociation stimulator 1
chr12_+_50484907	8.940		Foxg1	forkhead box G1
chr17_+_69506083	8.897	NM_013813	Epb4.1l3	erythrocyte protein band 4.1-like 3
chr1_-_159342351	8.868		Rasal2	RAS protein activator like 2
chr11_+_83223573	8.822	NM_001013386	Rasl10b	RAS-like, family 10, member B
chr5_-_38550627	8.720	NM_010942	Nsg1	neuron specific gene family member 1
chr10_-_80945445	8.638	NM_176954	Celf5	CUGBP, Elav-like family member 5
chr10_-_115910911	8.609		Kcnmb4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr18_-_25912453	8.609	NM_001146292 NM_001146293 NM_001146294 NM_001146295 NM_001174074 NM_133195	Celf4	CUGBP, Elav-like family member 4
chr12_+_109793151	8.594		Evl	Ena-vasodilator stimulated phosphoprotein
chr4_-_126430511	8.586	NM_011986	Ncdn	neurochondrin
chr13_-_55589463	8.542		Dbn1	drebrin 1
chr19_+_10463540	8.513	NM_018801 NM_173067 NM_173068	Syt7	synaptotagmin VII
chr10_+_81022304	8.207	NM_010347	Aes	amino-terminal enhancer of split
chr5_+_34339551	8.166		Nat8l	N-acetyltransferase 8-like
chr14_+_68701838	8.091	NM_010910	Nefl	neurofilament, light polypeptide
chr7_+_149135647	8.068	NM_029426	Brsk2	BR serine/threonine kinase 2
chr12_+_109792925	8.016	NM_001163394 NM_007965	Evl	Ena-vasodilator stimulated phosphoprotein
chr13_-_69877709	7.952		Ube2ql1	ubiquitin-conjugating enzyme E2Q family-like 1
chr7_+_129432810	7.941		Prkcb	protein kinase C, beta
chr17_+_86567513	7.937		Prkce	protein kinase C, epsilon
chr10_+_81022229	7.882		Aes	amino-terminal enhancer of split
chr2_+_156301651	7.789		Epb4.1l1	erythrocyte protein band 4.1-like 1
chr13_-_69138164	7.726		Adcy2	adenylate cyclase 2
chr19_-_5098498	7.670		Cnih2	cornichon homolog 2 (Drosophila)
chr8_+_11728104	7.664	NM_001113517	Arhgef7	Rho guanine nucleotide exchange factor (GEF7)
chr7_+_129432585	7.584	NM_008855	Prkcb	protein kinase C, beta
chr2_+_132607013	7.458	NM_007694	Chgb	chromogranin B
chr4_-_91038638	7.443		Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr5_-_139605617	7.421	NM_008923	Prkar1b	protein kinase, cAMP dependent regulatory, type I beta
chr7_-_64765360	7.290	NM_176942	Gabra5	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr11_+_102622745	7.206	NM_001110778 NM_009613	Adam11	a disintegrin and metallopeptidase domain 11
chr2_+_132607432	7.149		Chgb	chromogranin B
chr2_+_132607398	7.112		Chgb	chromogranin B
chr2_+_132607408	7.104		Chgb	chromogranin B
chr2_+_129419252	7.095		Sirpa	signal-regulatory protein alpha
chr2_+_28048511	7.088		Olfm1	olfactomedin 1
chr15_+_83610434	7.067	NM_172610	Mpped1	metallophosphoesterase domain containing 1
chr2_-_165060188	7.033	NM_174988	Cdh22	cadherin 22
chr12_+_112997057	7.027	NM_001025360 NM_001081959 NM_008450	Klc1	kinesin light chain 1
chr13_-_69138418	6.913	NM_153534	Adcy2	adenylate cyclase 2
chr15_+_87455659	6.897	NM_134096	Fam19a5	family with sequence similarity 19, member A5
chr2_-_73613381	6.890	NM_001113246 NM_001166603	Chn1	chimerin (chimaerin) 1
chr15_+_98465328	6.869		Cacnb3	calcium channel, voltage-dependent, beta 3 subunit
chr2_+_28048779	6.860		Olfm1	olfactomedin 1
chr7_-_112730004	6.814	NM_009685	Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1
chr7_-_117103903	6.726	NM_021494	Dennd5a	DENN/MADD domain containing 5A
chr12_-_113912266	6.569	NM_001165894 NM_009652	Akt1	thymoma viral proto-oncogene 1
chr7_-_88599560	6.542	NM_007755	Cpeb1	cytoplasmic polyadenylation element binding protein 1
chr15_-_27955680	6.538		Trio	triple functional domain (PTPRF interacting)
chr9_-_86775282	6.526		Snap91	synaptosomal-associated protein 91
chr11_-_5965743	6.520	NM_001174053 NM_001174054 NM_007595	Camk2b	calcium/calmodulin-dependent protein kinase II, beta
chr15_+_89330287	6.397	NM_021423	Shank3	SH3/ankyrin domain gene 3
chr11_+_80290571	6.391		Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr19_-_46392378	6.381		Psd	pleckstrin and Sec7 domain containing
chr8_+_41509109	6.341	NM_178395	Zdhhc2	zinc finger, DHHC domain containing 2
chr5_+_33361479	6.304		Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr4_-_150482562	6.236		Camta1	calmodulin binding transcription activator 1
chr11_-_58751993	6.216		Rnf187	ring finger protein 187
chr1_+_91351435	6.194		Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr7_+_19661548	6.184	NM_010058	Dmwd	dystrophia myotonica-containing WD repeat motif
chr11_+_102622885	6.164		Adam11	a disintegrin and metallopeptidase domain 11
chr8_+_86423968	6.136	NM_181039	Lphn1	latrophilin 1
chr2_+_156301543	6.011	NM_001006664	Epb4.1l1	erythrocyte protein band 4.1-like 1
chr15_-_44619541	5.994	NM_001032727 NM_176998	Sybu	syntabulin (syntaxin-interacting)
chr1_-_60099916	5.976	NM_027407	Ica1l	islet cell autoantigen 1-like
chr15_+_89284449	5.911		Mapk8ip2	mitogen-activated protein kinase 8 interacting protein 2
chr5_+_37259780	5.901	NM_172994	Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr16_-_91011339	5.834	NM_001045515 NM_001164483	Synj1	synaptojanin 1
chr11_-_6375845	5.708	NM_011221	Purb	purine rich element binding protein B
chr5_+_33361386	5.692	NM_011738	Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr14_-_46277274	5.687		Ddhd1	DDHD domain containing 1
chr7_+_19661811	5.669		Dmwd	dystrophia myotonica-containing WD repeat motif
chr2_+_28048592	5.659	NM_001038613 NM_001038614	Olfm1	olfactomedin 1
chr16_+_91270319	5.572		Olig1	oligodendrocyte transcription factor 1
chr18_-_16967754	5.546		Cdh2	cadherin 2
chr2_-_151458299	5.545		Snph	syntaphilin
chr9_-_20532657	5.525	NM_173777	Olfm2	olfactomedin 2
chr2_-_56976530	5.510		Nr4a2	nuclear receptor subfamily 4, group A, member 2
chr4_-_151235861	5.495	NM_001081557 NM_001195565	Camta1	calmodulin binding transcription activator 1
chr18_-_16967100	5.492		Cdh2	cadherin 2
chr15_+_83610459	5.492		Mpped1	metallophosphoesterase domain containing 1
chrX_+_5624624	5.492	NM_021431	Nudt11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr1_-_159342068	5.482		Rasal2	RAS protein activator like 2
chr10_+_81022283	5.412		Aes	amino-terminal enhancer of split
chr13_-_55589377	5.403	NM_001177371 NM_001177372 NM_019813	Dbn1	drebrin 1
chr17_+_24625943	5.356		Caskin1	CASK interacting protein 1
chr5_+_108797254	5.324		Gm10419	predicted gene 10419
chr11_-_5965544	5.289		Camk2b	calcium/calmodulin-dependent protein kinase II, beta
chr9_+_74919341	5.278		Myo5a	myosin VA
chr3_+_102538849	5.272		Tspan2	tetraspanin 2
chr3_+_138405156	5.266	NM_019571	Tspan5	tetraspanin 5
chr2_+_38194775	5.219		Lhx2	LIM homeobox protein 2
chr1_+_137043277	5.211	NM_026823	Arl8a	ADP-ribosylation factor-like 8A
chr6_+_118016385	5.189	NM_027526	Rasgef1a	RasGEF domain family, member 1A
chr5_+_37637027	5.122	NM_007765	Crmp1	collapsin response mediator protein 1
chr11_+_80290509	5.115	NM_009871	Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr19_+_36629213	5.097		Hectd2	HECT domain containing 2
chr1_-_16509276	5.036	NM_001111272 NM_025303	Stau2	staufen (RNA binding protein) homolog 2 (Drosophila)
chr12_+_86940000	5.025		Jdp2	Jun dimerization protein 2
chr3_-_138738152	5.015	NM_001040690 NM_145544	Rap1gds1	RAP1, GTP-GDP dissociation stimulator 1
chr9_-_62384846	5.012	NM_175484	Coro2b	coronin, actin binding protein, 2B
chr6_-_87931475	5.009	NM_198622	H1fx	H1 histone family, member X
chr17_-_66799086	4.966	NM_001114098 NM_172963	1110012J17Rik	RIKEN cDNA 1110012J17 gene
chr7_+_52419317	4.950		Slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr4_-_91038729	4.948	NM_010486 NM_207686	Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_+_142729505	4.931	NM_011212	Ptpre	protein tyrosine phosphatase, receptor type, E
chr9_-_53822931	4.913		Elmod1	ELMO domain containing 1
chr4_+_148960604	4.894	NM_023051	Clstn1	calsyntenin 1
chr5_-_139801315	4.860	NM_172723	Adap1	ArfGAP with dual PH domains 1
chr6_+_22825464	4.843	NM_001081306	Ptprz1	protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr11_-_76384852	4.843	NM_198895	Abr	active BCR-related gene
chr3_+_102538692	4.824	NM_027533	Tspan2	tetraspanin 2
chr18_+_32536846	4.798	NM_001083334 NM_009668	Bin1	bridging integrator 1
chr18_-_16967557	4.760	NM_007664	Cdh2	cadherin 2
chr7_+_52419289	4.759	NM_182993	Slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr14_+_104049411	4.750		Slain1	SLAIN motif family, member 1
chr10_-_79602040	4.749		Dos	downstream of Stk11
chr5_-_31597792	4.749	NM_022424	Fndc4	fibronectin type III domain containing 4
chr13_+_104899814	4.741		Sgtb	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr18_+_32536898	4.732		Bin1	bridging integrator 1
chr12_+_112997194	4.727		Klc1	kinesin light chain 1
chr1_-_191167582	4.726	NM_010607	Kcnk2	potassium channel, subfamily K, member 2
chr8_-_73316331	4.700	NM_199308	Mast3	microtubule associated serine/threonine kinase 3
chr11_+_102622915	4.689		Adam11	a disintegrin and metallopeptidase domain 11
chr10_+_59569206	4.651		Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr5_-_141306258	4.627	NM_010302	Gna12	guanine nucleotide binding protein, alpha 12
chr15_+_98465193	4.622	NM_007581	Cacnb3	calcium channel, voltage-dependent, beta 3 subunit
chr14_+_104049453	4.619	NM_198014	Slain1	SLAIN motif family, member 1
chr4_+_148960536	4.608		Clstn1	calsyntenin 1
chr5_-_121161656	4.604	NM_008052	Dtx1	deltex 1 homolog (Drosophila)
chr10_-_70062025	4.579	NM_178621	Phyhipl	phytanoyl-CoA hydroxylase interacting protein-like
chr18_+_37303622	4.569	NM_001003672	Pcdhac2	protocadherin alpha subfamily C, 2
chr13_-_59658585	4.561	NM_001048008 NM_023328	Agtpbp1	ATP/GTP binding protein 1
chr14_-_46277772	4.543		Ddhd1	DDHD domain containing 1
chr12_+_109572514	4.530	NM_010010	Cyp46a1	cytochrome P450, family 46, subfamily a, polypeptide 1
chr8_+_97296066	4.527	NM_009142	Cx3cl1	chemokine (C-X3-C motif) ligand 1
chr5_+_33361571	4.526		Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr4_-_41586992	4.523		Enho	energy homeostasis associated
chr12_+_75098739	4.520	NM_172804	Syt16	synaptotagmin XVI
chr7_-_31230463	4.507		Aplp1	amyloid beta (A4) precursor-like protein 1
chr11_+_6963421	4.496	NM_009622	Adcy1	adenylate cyclase 1
chr1_+_168184269	4.485	NM_001164528	Ildr2	immunoglobulin-like domain containing receptor 2
chr4_+_59202307	4.433		Ugcg	UDP-glucose ceramide glucosyltransferase
chr4_+_151552208	4.419	NM_133348	AU014716 Acot7	expressed sequence AU014716 acyl-CoA thioesterase 7
chr15_+_99501148	4.415	NM_009597	Accn2	amiloride-sensitive cation channel 2, neuronal
chr11_-_50024275	4.413	NM_011018	Sqstm1	sequestosome 1
chr5_+_88994019	4.408		Rufy3	RUN and FYVE domain containing 3
chr17_+_8533573	4.388	NM_178774	Prr18	proline rich region 18
chr2_-_33742951	4.381		Fam125b	family with sequence similarity 125, member B
chr14_-_7859962	4.377	NM_001164727	Gm10406	predicted gene 10406
chr15_+_74394184	4.373		Bai1	brain-specific angiogenesis inhibitor 1
chr1_+_91351373	4.361	NM_001037136 NM_178119	Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr17_+_25945986	4.344	NM_001164225	Fbxl16	F-box and leucine-rich repeat protein 16
chr4_+_126699209	4.330		Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr17_+_70318387	4.303		Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr9_-_53823107	4.300	NM_177769	Elmod1	ELMO domain containing 1
chr11_+_90110825	4.282		Mmd	monocyte to macrophage differentiation-associated
chr8_+_86424565	4.273		Lphn1	latrophilin 1
chr15_-_36426471	4.257		Ankrd46	ankyrin repeat domain 46
chr15_-_31297286	4.252	NM_001164441 NM_026153 NM_027496	Ankrd33b	ankyrin repeat domain 33B
chr4_-_57002965	4.250		6430704M03Rik	RIKEN cDNA 6430704M03 gene

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.42	2.43e-28	GO:0051179	localization
1.45	5.68e-26	GO:0051234	establishment of localization
1.45	7.36e-26	GO:0006810	transport
1.75	1.00e-23	GO:0008104	protein localization
1.24	1.15e-23	GO:0044237	cellular metabolic process
1.40	2.10e-23	GO:0071840	cellular component organization or biogenesis
1.40	1.68e-22	GO:0016043	cellular component organization
1.82	7.30e-22	GO:0045184	establishment of protein localization
1.80	1.50e-20	GO:0015031	protein transport
1.44	2.31e-20	GO:0071841	cellular component organization or biogenesis at cellular level
1.63	5.30e-20	GO:0033036	macromolecule localization
1.45	1.63e-19	GO:0071842	cellular component organization at cellular level
1.67	2.86e-19	GO:0051641	cellular localization
1.12	3.19e-19	GO:0009987	cellular process
1.27	5.21e-19	GO:0044260	cellular macromolecule metabolic process
1.62	7.58e-19	GO:0007399	nervous system development
1.55	1.07e-18	GO:0006996	organelle organization
1.21	2.70e-18	GO:0044238	primary metabolic process
1.42	5.43e-18	GO:0044267	cellular protein metabolic process
1.49	3.11e-17	GO:0006464	protein modification process
1.46	3.13e-16	GO:0043412	macromolecule modification
1.18	7.22e-16	GO:0008152	metabolic process
1.67	1.82e-15	GO:0051649	establishment of localization in cell
1.47	1.09e-13	GO:0023051	regulation of signaling
1.22	1.14e-13	GO:0043170	macromolecule metabolic process
1.76	1.26e-13	GO:0016192	vesicle-mediated transport
1.74	5.00e-13	GO:0046907	intracellular transport
1.24	3.77e-12	GO:0019222	regulation of metabolic process
1.26	9.70e-12	GO:0031323	regulation of cellular metabolic process
1.35	1.33e-11	GO:0048523	negative regulation of cellular process
1.33	2.15e-11	GO:0048519	negative regulation of biological process
1.48	5.31e-11	GO:0009966	regulation of signal transduction
1.78	1.11e-10	GO:0070727	cellular macromolecule localization
1.60	1.15e-10	GO:0048699	generation of neurons
1.57	1.26e-10	GO:0051128	regulation of cellular component organization
1.51	1.28e-10	GO:0006796	phosphate metabolic process
1.29	1.34e-10	GO:0019538	protein metabolic process
1.51	1.68e-10	GO:0006793	phosphorus metabolic process
1.57	2.08e-10	GO:0022008	neurogenesis
1.77	2.99e-10	GO:0034613	cellular protein localization
1.92	3.12e-10	GO:0031175	neuron projection development
1.25	1.07e-09	GO:0032502	developmental process
1.26	1.82e-09	GO:0007275	multicellular organismal development
1.72	2.09e-09	GO:0030030	cell projection organization
1.88	2.09e-09	GO:0006886	intracellular protein transport
1.75	2.50e-09	GO:0007010	cytoskeleton organization
1.29	3.44e-09	GO:0048522	positive regulation of cellular process
1.23	3.50e-09	GO:0080090	regulation of primary metabolic process
2.00	8.37e-09	GO:0051056	regulation of small GTPase mediated signal transduction
1.94	8.82e-09	GO:0007264	small GTPase mediated signal transduction
1.88	9.43e-09	GO:0070647	protein modification by small protein conjugation or removal
1.38	1.07e-08	GO:0065009	regulation of molecular function
1.46	1.21e-08	GO:0035556	intracellular signal transduction
1.29	1.56e-08	GO:0048731	system development
1.26	1.72e-08	GO:0048518	positive regulation of biological process
1.27	1.86e-08	GO:0048856	anatomical structure development
2.10	1.86e-08	GO:0031344	regulation of cell projection organization
2.00	2.35e-08	GO:0007017	microtubule-based process
1.93	6.68e-08	GO:0032446	protein modification by small protein conjugation
1.96	6.95e-08	GO:0048667	cell morphogenesis involved in neuron differentiation
1.97	8.18e-08	GO:0016567	protein ubiquitination
1.81	1.19e-07	GO:0009894	regulation of catabolic process
1.71	1.50e-07	GO:0048666	neuron development
1.61	3.75e-07	GO:0030182	neuron differentiation
1.30	3.99e-07	GO:0030154	cell differentiation
1.90	4.58e-07	GO:0048812	neuron projection morphogenesis
1.97	5.10e-07	GO:0046578	regulation of Ras protein signal transduction
1.70	6.32e-07	GO:0072521	purine-containing compound metabolic process
2.10	6.64e-07	GO:0006605	protein targeting
1.77	7.90e-07	GO:0050767	regulation of neurogenesis
1.43	9.90e-07	GO:0032268	regulation of cellular protein metabolic process
1.84	1.03e-06	GO:0019941	modification-dependent protein catabolic process
1.79	1.20e-06	GO:0000904	cell morphogenesis involved in differentiation
1.22	1.21e-06	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.84	1.22e-06	GO:0045664	regulation of neuron differentiation
1.29	1.29e-06	GO:0048869	cellular developmental process
1.84	1.45e-06	GO:0006511	ubiquitin-dependent protein catabolic process
1.75	1.47e-06	GO:0019226	transmission of nerve impulse
1.75	1.47e-06	GO:0035637	multicellular organismal signaling
1.94	1.47e-06	GO:0007409	axonogenesis
1.82	1.62e-06	GO:0043632	modification-dependent macromolecule catabolic process
1.32	1.96e-06	GO:0048583	regulation of response to stimulus
1.83	2.29e-06	GO:0031329	regulation of cellular catabolic process
1.46	3.06e-06	GO:0016310	phosphorylation
1.80	3.29e-06	GO:0051603	proteolysis involved in cellular protein catabolic process
2.05	3.47e-06	GO:0010975	regulation of neuron projection development
1.71	3.57e-06	GO:0006163	purine nucleotide metabolic process
1.78	4.25e-06	GO:0044257	cellular protein catabolic process
1.64	4.65e-06	GO:0061024	membrane organization
1.20	4.88e-06	GO:0060255	regulation of macromolecule metabolic process
2.35	6.15e-06	GO:0031346	positive regulation of cell projection organization
1.37	6.43e-06	GO:0050790	regulation of catalytic activity
1.64	6.58e-06	GO:0016044	cellular membrane organization
1.74	7.51e-06	GO:0030163	protein catabolic process
1.76	9.82e-06	GO:0009150	purine ribonucleotide metabolic process
1.39	1.01e-05	GO:0010646	regulation of cell communication
1.39	1.15e-05	GO:0051246	regulation of protein metabolic process
1.70	1.24e-05	GO:0051130	positive regulation of cellular component organization
1.74	1.27e-05	GO:0009259	ribonucleotide metabolic process
1.43	1.45e-05	GO:0048468	cell development
1.22	1.49e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.86	1.61e-05	GO:0009154	purine ribonucleotide catabolic process
1.85	1.71e-05	GO:0009261	ribonucleotide catabolic process
1.22	1.83e-05	GO:0051171	regulation of nitrogen compound metabolic process
1.78	2.21e-05	GO:0009205	purine ribonucleoside triphosphate metabolic process
1.83	2.29e-05	GO:0030029	actin filament-based process
1.44	2.31e-05	GO:0007049	cell cycle
1.72	2.31e-05	GO:0048858	cell projection morphogenesis
2.15	2.61e-05	GO:0033124	regulation of GTP catabolic process
1.65	2.67e-05	GO:0051960	regulation of nervous system development
1.19	2.79e-05	GO:0034641	cellular nitrogen compound metabolic process
2.63	2.90e-05	GO:0017157	regulation of exocytosis
1.38	3.01e-05	GO:0032879	regulation of localization
1.76	3.35e-05	GO:0009199	ribonucleoside triphosphate metabolic process
1.76	3.46e-05	GO:0009144	purine nucleoside triphosphate metabolic process
1.18	4.03e-05	GO:0006807	nitrogen compound metabolic process
1.61	5.15e-05	GO:0060284	regulation of cell development
2.12	5.71e-05	GO:0043087	regulation of GTPase activity
1.83	6.81e-05	GO:0009207	purine ribonucleoside triphosphate catabolic process
1.69	7.25e-05	GO:0032990	cell part morphogenesis
1.72	7.89e-05	GO:0009141	nucleoside triphosphate metabolic process
1.46	8.29e-05	GO:0006468	protein phosphorylation
1.82	8.54e-05	GO:0009203	ribonucleoside triphosphate catabolic process
1.88	8.85e-05	GO:0033365	protein localization to organelle
2.38	8.89e-05	GO:0007018	microtubule-based movement
1.78	8.95e-05	GO:0006195	purine nucleotide catabolic process
1.52	1.24e-04	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.81	1.33e-04	GO:0009146	purine nucleoside triphosphate catabolic process
1.76	1.41e-04	GO:0072523	purine-containing compound catabolic process
1.49	1.70e-04	GO:0022402	cell cycle process
1.42	1.70e-04	GO:0031399	regulation of protein modification process
1.57	2.06e-04	GO:0044265	cellular macromolecule catabolic process
1.73	2.22e-04	GO:0007268	synaptic transmission
1.56	2.31e-04	GO:0000902	cell morphogenesis
1.35	2.34e-04	GO:0044248	cellular catabolic process
1.42	2.59e-04	GO:0051049	regulation of transport
2.13	3.42e-04	GO:0050769	positive regulation of neurogenesis
1.77	3.90e-04	GO:0009143	nucleoside triphosphate catabolic process
1.53	3.99e-04	GO:0032989	cellular component morphogenesis
1.55	4.36e-04	GO:0051247	positive regulation of protein metabolic process
1.67	6.07e-04	GO:0034655	nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.67	6.07e-04	GO:0034656	nucleobase, nucleoside and nucleotide catabolic process
1.76	8.12e-04	GO:0030036	actin cytoskeleton organization
1.68	1.01e-03	GO:0009166	nucleotide catabolic process
1.57	1.01e-03	GO:0007610	behavior
1.50	1.04e-03	GO:0006753	nucleoside phosphate metabolic process
1.50	1.04e-03	GO:0009117	nucleotide metabolic process
2.41	1.18e-03	GO:0021543	pallium development
1.19	1.27e-03	GO:0031326	regulation of cellular biosynthetic process
1.41	1.28e-03	GO:0008219	cell death
1.43	1.30e-03	GO:0007154	cell communication
1.39	1.42e-03	GO:0045595	regulation of cell differentiation
1.34	1.61e-03	GO:0044085	cellular component biogenesis
1.40	1.70e-03	GO:0016265	death
1.30	1.86e-03	GO:0009056	catabolic process
1.19	2.22e-03	GO:0010468	regulation of gene expression
1.42	2.78e-03	GO:0012501	programmed cell death
1.20	2.94e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.32	2.96e-03	GO:0050793	regulation of developmental process
1.71	3.22e-03	GO:0006897	endocytosis
1.71	3.22e-03	GO:0010324	membrane invagination
1.90	3.29e-03	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.90	3.29e-03	GO:0022604	regulation of cell morphogenesis
1.90	3.29e-03	GO:0030811	regulation of nucleotide catabolic process
1.90	3.29e-03	GO:0033121	regulation of purine nucleotide catabolic process
1.52	3.87e-03	GO:0032270	positive regulation of cellular protein metabolic process
1.50	4.42e-03	GO:0060341	regulation of cellular localization
1.47	4.46e-03	GO:0009057	macromolecule catabolic process
1.18	4.47e-03	GO:0009889	regulation of biosynthetic process
1.43	4.96e-03	GO:0071844	cellular component assembly at cellular level
2.04	5.23e-03	GO:0032318	regulation of Ras GTPase activity
1.41	5.65e-03	GO:0006915	apoptosis
1.44	6.18e-03	GO:0051094	positive regulation of developmental process
1.79	6.20e-03	GO:0016311	dephosphorylation
1.89	7.01e-03	GO:0010720	positive regulation of cell development
1.52	7.04e-03	GO:0000278	mitotic cell cycle
1.34	7.12e-03	GO:0022607	cellular component assembly
1.20	7.16e-03	GO:0016070	RNA metabolic process
1.19	7.80e-03	GO:0010467	gene expression
2.11	8.16e-03	GO:0006836	neurotransmitter transport
1.32	8.23e-03	GO:0031324	negative regulation of cellular metabolic process
1.47	9.59e-03	GO:0051726	regulation of cell cycle
1.52	9.79e-03	GO:0006325	chromatin organization
1.58	1.05e-02	GO:0046700	heterocycle catabolic process
2.66	1.10e-02	GO:0050885	neuromuscular process controlling balance
1.57	1.20e-02	GO:0044270	cellular nitrogen compound catabolic process
1.93	1.27e-02	GO:0006184	GTP catabolic process
1.26	1.27e-02	GO:0009653	anatomical structure morphogenesis
2.02	1.27e-02	GO:0017038	protein import
1.22	1.37e-02	GO:0065008	regulation of biological quality
1.85	1.44e-02	GO:0007626	locomotory behavior
1.52	1.47e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.94	1.50e-02	GO:0006887	exocytosis
1.96	1.60e-02	GO:0021537	telencephalon development
1.80	1.77e-02	GO:0000226	microtubule cytoskeleton organization
2.59	1.80e-02	GO:0007269	neurotransmitter secretion
1.58	1.80e-02	GO:0018193	peptidyl-amino acid modification
1.59	1.85e-02	GO:0006140	regulation of nucleotide metabolic process
1.18	1.98e-02	GO:0010556	regulation of macromolecule biosynthetic process
1.81	2.02e-02	GO:0006813	potassium ion transport
1.29	2.27e-02	GO:0009892	negative regulation of metabolic process
1.37	2.28e-02	GO:0019220	regulation of phosphate metabolic process
1.37	2.28e-02	GO:0051174	regulation of phosphorus metabolic process
1.56	2.37e-02	GO:0033043	regulation of organelle organization
1.48	2.60e-02	GO:0045597	positive regulation of cell differentiation
1.33	2.62e-02	GO:0006811	ion transport
1.38	2.90e-02	GO:0046483	heterocycle metabolic process
2.19	2.96e-02	GO:0050905	neuromuscular process
2.59	2.96e-02	GO:0045685	regulation of glial cell differentiation
1.74	2.98e-02	GO:0042391	regulation of membrane potential
1.29	3.49e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.79	3.73e-02	GO:0031396	regulation of protein ubiquitination
2.24	3.80e-02	GO:0032886	regulation of microtubule-based process
2.40	3.93e-02	GO:0014013	regulation of gliogenesis
1.42	4.00e-02	GO:0051276	chromosome organization
2.05	4.33e-02	GO:0050770	regulation of axonogenesis
2.75	4.81e-02	GO:0021766	hippocampus development
1.51	4.90e-02	GO:0016568	chromatin modification
1.51	4.90e-02	GO:0032535	regulation of cellular component size

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.30	2.26e-102	GO:0005622	intracellular
1.30	1.52e-95	GO:0044424	intracellular part
1.35	1.43e-77	GO:0005737	cytoplasm
1.30	9.37e-71	GO:0043226	organelle
1.30	9.93e-71	GO:0043229	intracellular organelle
1.30	3.17e-59	GO:0043227	membrane-bounded organelle
1.30	3.02e-58	GO:0043231	intracellular membrane-bounded organelle
1.38	3.37e-49	GO:0044444	cytoplasmic part
1.13	7.11e-47	GO:0005623	cell
1.13	7.11e-47	GO:0044464	cell part
1.32	8.34e-30	GO:0005634	nucleus
1.35	6.22e-28	GO:0044422	organelle part
1.34	9.49e-27	GO:0044446	intracellular organelle part
2.00	5.07e-24	GO:0043005	neuron projection
1.59	1.14e-23	GO:0005829	cytosol
1.40	8.81e-23	GO:0043234	protein complex
1.35	5.70e-22	GO:0032991	macromolecular complex
2.02	2.61e-21	GO:0045202	synapse
1.64	6.73e-20	GO:0042995	cell projection
2.22	2.74e-17	GO:0030425	dendrite
2.09	2.74e-16	GO:0044456	synapse part
1.61	7.99e-16	GO:0005794	Golgi apparatus
1.98	1.94e-13	GO:0044297	cell body
1.98	8.83e-13	GO:0043025	neuronal cell body
1.85	2.14e-12	GO:0044463	cell projection part
1.47	8.98e-12	GO:0000267	cell fraction
1.31	2.37e-11	GO:0043228	non-membrane-bounded organelle
1.31	2.37e-11	GO:0043232	intracellular non-membrane-bounded organelle
1.56	1.02e-10	GO:0012505	endomembrane system
1.39	3.59e-10	GO:0005856	cytoskeleton
1.43	3.83e-10	GO:0031090	organelle membrane
1.54	2.97e-09	GO:0031982	vesicle
1.54	7.12e-09	GO:0031410	cytoplasmic vesicle
1.87	9.70e-09	GO:0044431	Golgi apparatus part
1.47	1.29e-08	GO:0005626	insoluble fraction
1.60	2.60e-08	GO:0015630	microtubule cytoskeleton
2.25	6.12e-08	GO:0019717	synaptosome
1.88	6.79e-08	GO:0030424	axon
1.54	1.52e-07	GO:0030054	cell junction
1.30	2.68e-07	GO:0044428	nuclear part
1.43	4.27e-07	GO:0044430	cytoskeletal part
1.44	4.31e-07	GO:0005624	membrane fraction
2.06	4.55e-07	GO:0030135	coated vesicle
2.16	1.58e-06	GO:0033267	axon part
2.10	1.72e-06	GO:0030136	clathrin-coated vesicle
1.18	6.23e-06	GO:0071944	cell periphery
2.00	6.32e-06	GO:0045211	postsynaptic membrane
1.57	1.32e-05	GO:0005768	endosome
2.25	1.95e-05	GO:0008021	synaptic vesicle
2.35	3.26e-05	GO:0030427	site of polarized growth
1.67	3.84e-05	GO:0048471	perinuclear region of cytoplasm
2.42	4.15e-05	GO:0044309	neuron spine
1.71	5.06e-05	GO:0005874	microtubule
1.17	5.06e-05	GO:0005886	plasma membrane
2.42	6.75e-05	GO:0043197	dendritic spine
2.26	1.63e-04	GO:0005802	trans-Golgi network
2.24	4.22e-04	GO:0030426	growth cone
1.81	5.10e-04	GO:0034702	ion channel complex
2.87	5.36e-04	GO:0043198	dendritic shaft
1.44	6.68e-04	GO:0031988	membrane-bounded vesicle
1.40	7.80e-04	GO:0031975	envelope
2.19	8.48e-04	GO:0014069	postsynaptic density
1.45	8.63e-04	GO:0016023	cytoplasmic membrane-bounded vesicle
1.26	9.06e-04	GO:0031981	nuclear lumen
2.05	9.25e-04	GO:0034703	cation channel complex
2.50	9.45e-04	GO:0030665	clathrin coated vesicle membrane
2.18	1.35e-03	GO:0016585	chromatin remodeling complex
1.77	1.72e-03	GO:0012506	vesicle membrane
1.98	1.85e-03	GO:0000151	ubiquitin ligase complex
1.52	1.89e-03	GO:0005625	soluble fraction
1.67	2.13e-03	GO:0005815	microtubule organizing center
2.73	2.69e-03	GO:0000118	histone deacetylase complex
1.38	3.03e-03	GO:0031967	organelle envelope
2.22	3.18e-03	GO:0030662	coated vesicle membrane
1.69	3.52e-03	GO:0005813	centrosome
1.75	7.48e-03	GO:0000139	Golgi membrane
1.20	7.75e-03	GO:0044459	plasma membrane part
1.28	9.42e-03	GO:0005654	nucleoplasm
2.76	1.20e-02	GO:0008287	protein serine/threonine phosphatase complex
1.21	1.20e-02	GO:0031974	membrane-enclosed lumen
2.42	1.73e-02	GO:0005905	coated pit
1.70	2.01e-02	GO:0044433	cytoplasmic vesicle part
2.18	2.10e-02	GO:0030117	membrane coat
2.18	2.10e-02	GO:0048475	coated membrane
1.88	2.21e-02	GO:0019898	extrinsic to membrane
1.20	2.32e-02	GO:0070013	intracellular organelle lumen
1.20	2.74e-02	GO:0043233	organelle lumen
2.47	3.05e-02	GO:0042734	presynaptic membrane
1.69	3.45e-02	GO:0030659	cytoplasmic vesicle membrane
3.11	4.27e-02	GO:0019005	SCF ubiquitin ligase complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.23	2.18e-57	GO:0005488	binding
1.39	3.42e-53	GO:0005515	protein binding
1.48	5.01e-24	GO:0000166	nucleotide binding
1.50	1.42e-20	GO:0032553	ribonucleotide binding
1.49	2.22e-20	GO:0032555	purine ribonucleotide binding
1.49	5.76e-20	GO:0017076	purine nucleotide binding
1.49	1.34e-19	GO:0035639	purine ribonucleoside triphosphate binding
1.62	4.62e-14	GO:0019899	enzyme binding
1.92	6.97e-14	GO:0060589	nucleoside-triphosphatase regulator activity
1.91	3.46e-13	GO:0030695	GTPase regulator activity
1.20	2.06e-12	GO:0003824	catalytic activity
1.41	3.49e-11	GO:0032559	adenyl ribonucleotide binding
1.41	7.64e-11	GO:0030554	adenyl nucleotide binding
1.71	9.96e-11	GO:0019904	protein domain specific binding
2.02	3.28e-10	GO:0005083	small GTPase regulator activity
1.40	4.67e-10	GO:0005524	ATP binding
1.51	2.67e-09	GO:0030234	enzyme regulator activity
1.84	2.88e-09	GO:0005525	GTP binding
2.11	3.61e-09	GO:0019787	small conjugating protein ligase activity
2.02	5.66e-09	GO:0016881	acid-amino acid ligase activity
1.23	1.41e-08	GO:0046872	metal ion binding
1.33	2.14e-08	GO:0016740	transferase activity
1.50	3.04e-08	GO:0016301	kinase activity
1.77	4.17e-08	GO:0019001	guanyl nucleotide binding
1.77	4.17e-08	GO:0032561	guanyl ribonucleotide binding
1.22	4.87e-08	GO:0043169	cation binding
1.54	5.16e-08	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.22	5.69e-08	GO:0043167	ion binding
2.07	8.49e-08	GO:0004842	ubiquitin-protein ligase activity
1.61	1.39e-07	GO:0008092	cytoskeletal protein binding
1.89	1.55e-07	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.44	2.73e-07	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.45	3.30e-07	GO:0022892	substrate-specific transporter activity
1.76	6.19e-07	GO:0008047	enzyme activator activity
1.39	1.20e-06	GO:0005215	transporter activity
1.91	2.48e-06	GO:0005096	GTPase activator activity
2.19	4.05e-06	GO:0005516	calmodulin binding
2.59	4.68e-06	GO:0008565	protein transporter activity
1.63	5.82e-06	GO:0016874	ligase activity
1.52	6.47e-06	GO:0004672	protein kinase activity
1.61	9.49e-06	GO:0004674	protein serine/threonine kinase activity
1.46	1.78e-05	GO:0015075	ion transmembrane transporter activity
1.31	2.08e-05	GO:0008270	zinc ion binding
1.70	2.26e-05	GO:0019900	kinase binding
1.42	2.52e-05	GO:0022891	substrate-specific transmembrane transporter activity
1.63	3.35e-05	GO:0032403	protein complex binding
2.09	5.13e-05	GO:0051020	GTPase binding
1.38	1.15e-04	GO:0022857	transmembrane transporter activity
1.92	2.47e-04	GO:0003924	GTPase activity
1.66	2.73e-04	GO:0022836	gated channel activity
1.49	2.79e-04	GO:0008324	cation transmembrane transporter activity
1.72	2.97e-04	GO:0016791	phosphatase activity
1.70	3.10e-04	GO:0019901	protein kinase binding
2.08	4.20e-04	GO:0031267	small GTPase binding
1.42	4.46e-04	GO:0016462	pyrophosphatase activity
1.41	6.21e-04	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.41	6.93e-04	GO:0016817	hydrolase activity, acting on acid anhydrides
1.42	7.65e-04	GO:0017111	nucleoside-triphosphatase activity
1.54	1.25e-03	GO:0005216	ion channel activity
1.76	2.59e-03	GO:0005244	voltage-gated ion channel activity
1.76	2.59e-03	GO:0022832	voltage-gated channel activity
1.90	2.60e-03	GO:0022843	voltage-gated cation channel activity
1.37	2.75e-03	GO:0003723	RNA binding
1.50	3.79e-03	GO:0022838	substrate-specific channel activity
1.54	4.71e-03	GO:0042578	phosphoric ester hydrolase activity
2.00	5.23e-03	GO:0017016	Ras GTPase binding
1.48	6.05e-03	GO:0015267	channel activity
2.10	6.24e-03	GO:0019887	protein kinase regulator activity
1.76	6.25e-03	GO:0008022	protein C-terminus binding
1.48	6.88e-03	GO:0022803	passive transmembrane transporter activity
2.59	7.85e-03	GO:0000149	SNARE binding
2.85	1.20e-02	GO:0019003	GDP binding
2.75	1.27e-02	GO:0015179	L-amino acid transmembrane transporter activity
2.04	1.79e-02	GO:0005099	Ras GTPase activator activity
1.77	1.80e-02	GO:0015077	monovalent inorganic cation transmembrane transporter activity
2.09	1.80e-02	GO:0015081	sodium ion transmembrane transporter activity
1.21	1.93e-02	GO:0046914	transition metal ion binding
1.75	2.65e-02	GO:0005085	guanyl-nucleotide exchange factor activity
1.85	2.91e-02	GO:0017124	SH3 domain binding
1.90	3.58e-02	GO:0019207	kinase regulator activity
1.71	4.12e-02	GO:0004721	phosphoprotein phosphatase activity
1.56	4.35e-02	GO:0000988	protein binding transcription factor activity
1.56	4.43e-02	GO:0003712	transcription cofactor activity