Motif ID: TFCP2.p2

Z-value: 2.914


Transcription factors associated with TFCP2.p2:

Gene SymbolEntrez IDGene Name
Tcfcp2 21422 transcription factor CP2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcfcp2chr15_-_1003823540.321.2e-05Click!


Activity profile for motif TFCP2.p2.

activity profile for motif TFCP2.p2


Sorted Z-values histogram for motif TFCP2.p2

Sorted Z-values for motif TFCP2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFCP2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_81361077 59.218 Actn1
actinin, alpha 1
chr11_-_100275977 42.953 Leprel4
leprecan-like 4
chr11_-_100276112 40.888 NM_176830
Leprel4
leprecan-like 4
chr7_-_106501584 39.556 Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr7_-_106501642 37.564 NM_001111043
NM_001111044
NM_009825
Serpinh1


serine (or cysteine) peptidase inhibitor, clade H, member 1


chr7_-_106501620 34.828 Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr16_+_37777075 34.158 NM_008047
Fstl1
follistatin-like 1
chr19_+_10116079 33.493 Fads3
fatty acid desaturase 3
chr12_-_81361302 30.501 NM_134156
Actn1
actinin, alpha 1
chr1_-_82287990 29.805 NM_010570
Irs1
insulin receptor substrate 1
chr11_+_29593657 28.983 NM_194051
Rtn4
reticulon 4
chr16_-_85173851 28.736 App
amyloid beta (A4) precursor protein
chr4_-_55545211 28.536 Klf4
Kruppel-like factor 4 (gut)
chrX_-_49518428 28.421 Gpc4
glypican 4
chr9_-_58160063 28.036 Loxl1
lysyl oxidase-like 1
chr16_-_85173918 27.089 App
amyloid beta (A4) precursor protein
chr16_-_85173944 26.839 NM_001198823
NM_001198824
NM_001198825
NM_001198826
NM_007471
App




amyloid beta (A4) precursor protein




chr3_+_104591946 26.597 NM_007484
Rhoc
ras homolog gene family, member C
chr16_-_85173930 26.541 App
amyloid beta (A4) precursor protein
chr7_-_149763980 25.931 H19
H19 fetal liver mRNA
chr3_+_90417072 25.861 S100a6
S100 calcium binding protein A6 (calcyclin)
chr16_-_85173978 25.596 App
amyloid beta (A4) precursor protein
chr3_+_90416815 25.586 NM_011313
S100a6
S100 calcium binding protein A6 (calcyclin)
chr3_+_104591955 25.374 Rhoc
ras homolog gene family, member C
chr16_-_85173764 25.311 App
amyloid beta (A4) precursor protein
chr12_+_30687597 23.755 Pxdn
peroxidasin homolog (Drosophila)
chr2_+_109757803 23.051 NM_172671
Lgr4
leucine-rich repeat-containing G protein-coupled receptor 4
chr2_+_156601150 22.764 Myl9
myosin, light polypeptide 9, regulatory
chr12_+_8778260 22.697 Sdc1
syndecan 1
chr13_+_111185251 21.405 NM_152804
Plk2
polo-like kinase 2 (Drosophila)
chr19_+_10116001 21.162 NM_021890
Fads3
fatty acid desaturase 3
chr19_+_45092581 21.089 NM_001130526
Lzts2
leucine zipper, putative tumor suppressor 2
chr11_+_94811409 21.051 Col1a1
collagen, type I, alpha 1
chr2_-_60800963 21.010 Rbms1
RNA binding motif, single stranded interacting protein 1
chr4_-_55545337 20.955 NM_010637
Klf4
Kruppel-like factor 4 (gut)
chr19_+_45101318 20.910 Lzts2
leucine zipper, putative tumor suppressor 2
chr7_-_139346304 20.416 Cpxm2
carboxypeptidase X 2 (M14 family)
chr7_+_138079669 19.474 NM_019564
Htra1
HtrA serine peptidase 1
chr19_+_5068077 18.766 NM_054042
Cd248
CD248 antigen, endosialin
chr4_+_43644806 18.721 NM_173788
Npr2
natriuretic peptide receptor 2
chr3_+_93324411 18.634 NM_016740
S100a11
S100 calcium binding protein A11 (calgizzarin)
chr8_+_77617514 18.426 NM_010442
Hmox1
heme oxygenase (decycling) 1
chr9_+_92437056 18.123 NM_001142916
NM_011961
Plod2

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

chr19_+_10116104 17.735 Fads3
fatty acid desaturase 3
chr3_+_93324437 17.394 S100a11
S100 calcium binding protein A11 (calgizzarin)
chr13_-_64471609 17.184 NM_009984
Ctsl
cathepsin L
chr15_-_89011113 17.106 NM_138749
Plxnb2
plexin B2
chr8_-_35040277 17.080 NM_001042674
NM_001042675
NM_019733
Rbpms


RNA binding protein gene with multiple splicing


chr19_+_5475020 16.939 Efemp2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr1_+_172574698 16.890 Olfml2b
olfactomedin-like 2B
chr1_+_172574668 16.712 Olfml2b
olfactomedin-like 2B
chr8_+_46970814 16.644 NM_016798
Pdlim3
PDZ and LIM domain 3
chr6_+_56828743 16.538 Fkbp9
FK506 binding protein 9
chr7_+_137836116 16.526 Tacc2
transforming, acidic coiled-coil containing protein 2
chr9_+_50561315 16.484 Cryab
crystallin, alpha B
chr9_+_69301471 16.300 NM_007585
Anxa2
annexin A2
chr10_+_85763156 16.070 NM_011595
Timp3
tissue inhibitor of metalloproteinase 3
chr1_+_172574662 16.041 NM_177068
Olfml2b
olfactomedin-like 2B
chr10_+_85763267 16.038 Timp3
tissue inhibitor of metalloproteinase 3
chr15_-_10643806 15.942 Rai14
retinoic acid induced 14
chr8_-_35040236 15.876 Rbpms
RNA binding protein gene with multiple splicing
chr2_-_148233681 15.867 Thbd
thrombomodulin
chr2_-_148233853 15.771 NM_009378
Thbd
thrombomodulin
chr2_-_60800904 15.758 Rbms1
RNA binding motif, single stranded interacting protein 1
chr10_+_85763294 15.352 Timp3
tissue inhibitor of metalloproteinase 3
chr3_+_68298129 15.190 Schip1
schwannomin interacting protein 1
chr7_+_137836279 15.120 Tacc2
transforming, acidic coiled-coil containing protein 2
chr6_-_125444722 15.058 NM_007657
Cd9
CD9 antigen
chr10_+_125403274 14.864 NM_177152
Lrig3
leucine-rich repeats and immunoglobulin-like domains 3
chr1_-_51972718 14.858 Myo1b
myosin IB
chr2_-_60801248 14.720 NM_020296
Rbms1
RNA binding motif, single stranded interacting protein 1
chr10_+_85763287 14.720 Timp3
tissue inhibitor of metalloproteinase 3
chr6_-_72739189 14.686 Tcf7l1
transcription factor 7-like 1 (T-cell specific, HMG box)
chr13_-_49063188 14.382 NM_001033268
Fam120a
family with sequence similarity 120, member A
chr12_+_8778152 14.323 Sdc1
syndecan 1
chr4_+_118905490 14.308 NM_019782
NM_019783
Lepre1

leprecan 1

chr4_+_136833403 14.302 NM_009523
Wnt4
wingless-related MMTV integration site 4
chr9_+_50561092 14.091 Cryab
crystallin, alpha B
chr10_+_85763303 13.982 Timp3
tissue inhibitor of metalloproteinase 3
chr13_-_78337844 13.600 Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr7_-_108971734 13.569


chr13_-_115249048 13.552 Fst
follistatin
chr3_+_96405063 13.470 Lix1l
Lix1-like
chr15_-_77136972 13.397 Rbfox2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_-_125444695 13.357 Cd9
CD9 antigen
chr15_+_78673024 13.315 NM_027219
Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr12_-_112615921 13.295 NM_183016
Cdc42bpb
CDC42 binding protein kinase beta
chr9_+_50561121 13.290 Cryab
crystallin, alpha B
chr3_-_57379831 13.195 NM_001168281
Wwtr1
WW domain containing transcription regulator 1
chr11_-_118216819 13.122 Timp2
tissue inhibitor of metalloproteinase 2
chr12_-_113912266 12.941 NM_001165894
NM_009652
Akt1

thymoma viral proto-oncogene 1

chr11_-_118216689 12.887 NM_011594
Timp2
tissue inhibitor of metalloproteinase 2
chr14_+_102129129 12.878 NM_201529
Lmo7
LIM domain only 7
chr11_+_29592897 12.769 NM_194052
NM_194053
NM_194054
Rtn4


reticulon 4


chr2_-_165980462 12.723 Sulf2
sulfatase 2
chr5_-_139470895 12.716 NM_008808
Pdgfa
platelet derived growth factor, alpha
chr3_+_96404978 12.607 NM_001163170
Lix1l
Lix1-like
chr18_+_6765174 12.557 NM_181070
Rab18
RAB18, member RAS oncogene family
chr11_-_76212487 12.463 Nxn
nucleoredoxin
chr2_+_156601175 12.441 NM_172118
Myl9
myosin, light polypeptide 9, regulatory
chr14_+_34899165 12.434 NM_013473
Anxa8
annexin A8
chr1_-_51972816 12.237 NM_001161817
NM_010863
Myo1b

myosin IB

chr10_-_120335907 12.191 NM_177092
Msrb3
methionine sulfoxide reductase B3
chr19_-_34329804 12.097 NM_007392
Acta2
actin, alpha 2, smooth muscle, aorta
chr5_-_139470785 12.017 Pdgfa
platelet derived growth factor, alpha
chr14_-_26722378 12.011 NM_207229
Plac9
placenta specific 9
chr9_+_50561381 11.986 Cryab
crystallin, alpha B
chr12_+_8778201 11.903 NM_011519
Sdc1
syndecan 1
chr1_-_137271539 11.861 NM_175259
Shisa4
shisa homolog 4 (Xenopus laevis)
chr18_-_34166572 11.857 Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr8_-_94325138 11.805 NM_008393
Irx3
Iroquois related homeobox 3 (Drosophila)
chr1_+_94728217 11.797 NM_016696
Gpc1
glypican 1
chr11_-_120685418 11.740 Fasn
fatty acid synthase
chr3_-_57379600 11.695 NM_133784
Wwtr1
WW domain containing transcription regulator 1
chr11_+_29592946 11.679 Rtn4
reticulon 4
chr5_-_67009992 11.537 Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr1_-_51972771 11.506 Myo1b
myosin IB
chr11_+_76015590 11.478 Fam57a
family with sequence similarity 57, member A
chr9_+_50560862 11.376 NM_009964
Cryab
crystallin, alpha B
chr16_-_8672226 11.303 Carhsp1
calcium regulated heat stable protein 1
chr7_+_137836057 11.274 NM_021314
Tacc2
transforming, acidic coiled-coil containing protein 2
chr5_-_145726643 11.216 NM_001038627
NM_029438
Smurf1

SMAD specific E3 ubiquitin protein ligase 1

chr19_-_5349573 11.191 NM_028623
Cst6
cystatin E/M
chr9_+_106356125 11.161 NM_021567
Pcbp4
poly(rC) binding protein 4
chr6_-_72738861 11.082 Tcf7l1
transcription factor 7-like 1 (T-cell specific, HMG box)
chr18_+_58038278 11.005 NM_009194
Slc12a2
solute carrier family 12, member 2
chr1_+_94728419 10.997 Gpc1
glypican 1
chr2_+_27741864 10.995 NM_015734
Col5a1
collagen, type V, alpha 1
chr11_+_53915017 10.939 P4ha2
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide
chr5_-_31210160 10.899 NM_024460
Ost4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr10_-_60610398 10.834 NM_009163
Sgpl1
sphingosine phosphate lyase 1
chr7_-_96666035 10.773 Prss23
protease, serine, 23
chr16_-_8672242 10.770 NM_025821
Carhsp1
calcium regulated heat stable protein 1
chr6_-_92656148 10.729 NM_001081146
Prickle2
prickle homolog 2 (Drosophila)
chr16_+_33829715 10.691 NM_001145884
NM_010580
Itgb5

integrin beta 5

chr16_-_85803359 10.617 NM_009621
Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr3_+_120994646 10.617 NM_024178
Alg14
asparagine-linked glycosylation 14 homolog (yeast)
chr15_-_77137015 10.615 Rbfox2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr13_-_115248924 10.601 NM_008046
Fst
follistatin
chr19_-_7292057 10.579 Cox8a
cytochrome c oxidase, subunit VIIIa
chr11_-_3439172 10.530 NM_001159284
NM_013870
Smtn

smoothelin

chr5_+_37729746 10.523 Evc2
Ellis van Creveld syndrome 2 homolog (human)
chrX_-_147248815 10.505 NM_030700
Maged2
melanoma antigen, family D, 2
chr19_-_7292086 10.469 NM_007750
Cox8a
cytochrome c oxidase, subunit VIIIa
chr18_-_34166859 10.440 NM_013512
Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr19_+_7492081 10.425 NM_175381
2700081O15Rik
RIKEN cDNA 2700081O15 gene
chr3_+_55046447 10.353 NM_001111053
NM_001195538
NM_019978
Dclk1


doublecortin-like kinase 1


chr5_+_37729712 10.340 NM_145920
Evc2
Ellis van Creveld syndrome 2 homolog (human)
chr5_-_67009869 10.224 NM_009686
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr19_+_27292039 10.208 Vldlr
very low density lipoprotein receptor
chr11_-_20731016 10.160 NM_173752
1110067D22Rik
RIKEN cDNA 1110067D22 gene
chr7_+_119571219 10.150 NM_020606
Parva
parvin, alpha
chr17_-_15963016 10.126 Rgmb
RGM domain family, member B
chr13_-_115248787 10.114 Fst
follistatin
chr5_+_91946651 10.073 NM_145562
Parm1
prostate androgen-regulated mucin-like protein 1
chr2_-_130223285 10.057 NM_019696
Cpxm1
carboxypeptidase X 1 (M14 family)
chr13_-_64471562 10.029 Ctsl
cathepsin L
chr11_+_101192080 10.003 Aoc3
amine oxidase, copper containing 3
chr16_-_85803343 9.926 Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr1_-_74350713 9.896 Tmbim1
transmembrane BAX inhibitor motif containing 1
chr10_-_58684199 9.895 Sept10
septin 10
chr17_+_43804373 9.880 NM_018887
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr12_+_87423503 9.803 NM_029601
1700019E19Rik
RIKEN cDNA 1700019E19 gene
chr8_-_26127211 9.737 Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr1_+_75356913 9.696 NM_010043
Des
desmin
chr16_-_85901362 9.670 NM_011782
Adamts5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
chr12_+_110779204 9.666 Meg3
maternally expressed 3
chr10_+_77888414 9.663 NM_007793
Cstb
cystatin B
chr16_+_62854129 9.644 NM_011173
Pros1
protein S (alpha)
chr11_+_53333270 9.598 NM_033144
Sept8
septin 8
chr7_-_16552844 9.588 NM_153068
Ehd2
EH-domain containing 2
chr8_-_26127376 9.563 NM_007404
Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr6_-_72738935 9.560 NM_001079822
NM_009332
Tcf7l1

transcription factor 7-like 1 (T-cell specific, HMG box)

chr1_-_74350909 9.553 NM_027154
Tmbim1
transmembrane BAX inhibitor motif containing 1
chr6_+_17256415 9.461 Cav1
caveolin 1, caveolae protein
chr14_+_70009282 9.435 NM_033325
Loxl2
lysyl oxidase-like 2
chr10_+_58684631 9.423 NM_172939
Ankrd57
ankyrin repeat domain 57
chr14_-_47006944 9.407 Bmp4
bone morphogenetic protein 4
chr8_-_26127346 9.402 Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr19_-_36811137 9.391 Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr1_+_89951985 9.376 NM_201641
Ugt1a10
UDP glycosyltransferase 1 family, polypeptide A10
chr10_+_79317396 9.336 Ptbp1
polypyrimidine tract binding protein 1
chr6_+_117118552 9.331 NM_001012477
NM_013655
NM_021704
Cxcl12


chemokine (C-X-C motif) ligand 12


chr12_+_113960424 9.293 AW555464
expressed sequence AW555464
chr3_+_55046548 9.264 Dclk1
doublecortin-like kinase 1
chr1_+_75356906 9.239 Des
desmin
chr12_-_59369833 9.237 Clec14a
C-type lectin domain family 14, member a
chr13_-_49063376 9.220 Fam120a
family with sequence similarity 120, member A
chr9_-_58160966 9.209 NM_010729
Loxl1
lysyl oxidase-like 1
chr15_+_34167908 9.186 Laptm4b
lysosomal-associated protein transmembrane 4B
chr19_-_7292009 9.165 Cox8a
cytochrome c oxidase, subunit VIIIa
chr5_-_36740713 9.103 NM_030889
Sorcs2
sortilin-related VPS10 domain containing receptor 2
chr15_+_34167780 9.080 NM_033521
Laptm4b
lysosomal-associated protein transmembrane 4B
chr6_+_17256369 9.020 NM_007616
Cav1
caveolin 1, caveolae protein
chr7_-_20334814 9.000 Pvrl2
poliovirus receptor-related 2
chr19_+_5741862 8.988 Ltbp3
latent transforming growth factor beta binding protein 3
chr7_+_3290587 8.964 Myadm
myeloid-associated differentiation marker
chr9_-_21602942 8.943 NM_145611
Kank2
KN motif and ankyrin repeat domains 2
chr7_+_3290622 8.935 Myadm
myeloid-associated differentiation marker
chr18_-_34166105 8.862 Epb4.1l4a
erythrocyte protein band 4.1-like 4a

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.61 9.37e-28 GO:0007275 multicellular organismal development
1.68 4.23e-27 GO:0048731 system development
1.57 7.06e-27 GO:0032502 developmental process
1.62 1.64e-25 GO:0048856 anatomical structure development
1.88 7.15e-23 GO:0009653 anatomical structure morphogenesis
1.55 1.47e-21 GO:0016043 cellular component organization
1.59 2.19e-21 GO:0048522 positive regulation of cellular process
1.63 5.03e-20 GO:0048523 negative regulation of cellular process
1.50 4.00e-19 GO:0071840 cellular component organization or biogenesis
1.58 9.09e-19 GO:0048519 negative regulation of biological process
1.51 3.57e-18 GO:0048518 positive regulation of biological process
2.34 1.01e-17 GO:0072358 cardiovascular system development
2.34 1.01e-17 GO:0072359 circulatory system development
1.94 4.97e-16 GO:0009888 tissue development
2.59 5.41e-15 GO:0001944 vasculature development
2.67 5.45e-15 GO:0001568 blood vessel development
1.93 2.33e-14 GO:0051128 regulation of cellular component organization
1.55 5.13e-14 GO:0048869 cellular developmental process
1.75 5.56e-14 GO:0007399 nervous system development
1.56 5.79e-14 GO:0030154 cell differentiation
1.59 1.41e-13 GO:0048513 organ development
1.58 2.12e-13 GO:0065008 regulation of biological quality
1.51 7.78e-13 GO:0071842 cellular component organization at cellular level
1.78 9.06e-13 GO:0050793 regulation of developmental process
2.13 9.32e-13 GO:0048646 anatomical structure formation involved in morphogenesis
1.40 1.02e-12 GO:0051179 localization
1.70 3.51e-12 GO:0009966 regulation of signal transduction
1.89 4.70e-12 GO:0048699 generation of neurons
1.22 7.37e-12 GO:0008152 metabolic process
1.24 1.56e-11 GO:0044237 cellular metabolic process
1.79 1.74e-11 GO:0042127 regulation of cell proliferation
1.47 2.57e-11 GO:0071841 cellular component organization or biogenesis at cellular level
2.09 4.57e-11 GO:0043009 chordate embryonic development
1.72 7.47e-11 GO:0010941 regulation of cell death
1.82 7.80e-11 GO:0022008 neurogenesis
2.06 1.32e-10 GO:0009792 embryo development ending in birth or egg hatching
2.84 3.15e-10 GO:0001525 angiogenesis
1.58 3.55e-10 GO:0023051 regulation of signaling
1.77 3.66e-10 GO:0022607 cellular component assembly
1.76 5.87e-10 GO:2000026 regulation of multicellular organismal development
2.30 1.26e-09 GO:0051270 regulation of cellular component movement
1.69 1.39e-09 GO:0043067 regulation of programmed cell death
1.52 2.12e-09 GO:0044281 small molecule metabolic process
1.30 3.04e-09 GO:0019222 regulation of metabolic process
1.62 3.25e-09 GO:0033036 macromolecule localization
2.88 3.28e-09 GO:0050678 regulation of epithelial cell proliferation
1.69 3.47e-09 GO:0042981 regulation of apoptosis
2.16 3.57e-09 GO:0048729 tissue morphogenesis
2.47 3.65e-09 GO:0048514 blood vessel morphogenesis
1.74 4.68e-09 GO:0048468 cell development
2.00 6.51e-09 GO:0009967 positive regulation of signal transduction
1.21 6.58e-09 GO:0044238 primary metabolic process
2.74 7.43e-09 GO:0043062 extracellular structure organization
2.31 7.86e-09 GO:2000145 regulation of cell motility
1.75 8.17e-09 GO:0009790 embryo development
1.37 9.63e-09 GO:0051234 establishment of localization
2.31 1.07e-08 GO:0030334 regulation of cell migration
1.53 1.63e-08 GO:0051239 regulation of multicellular organismal process
2.21 1.99e-08 GO:0040012 regulation of locomotion
2.76 2.15e-08 GO:0060537 muscle tissue development
1.50 2.42e-08 GO:0048583 regulation of response to stimulus
2.02 2.70e-08 GO:0006461 protein complex assembly
2.12 3.23e-08 GO:0008285 negative regulation of cell proliferation
2.01 3.60e-08 GO:0070271 protein complex biogenesis
2.36 4.19e-08 GO:0051259 protein oligomerization
1.37 4.42e-08 GO:0006810 transport
2.14 5.00e-08 GO:0022603 regulation of anatomical structure morphogenesis
1.98 5.27e-08 GO:0071822 protein complex subunit organization
1.73 5.55e-08 GO:0045595 regulation of cell differentiation
2.29 6.31e-08 GO:0007264 small GTPase mediated signal transduction
1.63 8.97e-08 GO:0051641 cellular localization
1.61 9.17e-08 GO:0051246 regulation of protein metabolic process
1.89 1.07e-07 GO:0030182 neuron differentiation
2.43 1.27e-07 GO:0048732 gland development
1.81 1.27e-07 GO:0009887 organ morphogenesis
2.14 1.45e-07 GO:0035295 tube development
2.02 1.46e-07 GO:0060429 epithelium development
1.30 1.54e-07 GO:0031323 regulation of cellular metabolic process
2.19 1.54e-07 GO:0001701 in utero embryonic development
1.62 1.63e-07 GO:0044085 cellular component biogenesis
1.70 1.74e-07 GO:0045184 establishment of protein localization
1.63 2.05e-07 GO:0032268 regulation of cellular protein metabolic process
2.08 2.41e-07 GO:0007167 enzyme linked receptor protein signaling pathway
2.24 2.53e-07 GO:0007507 heart development
1.61 2.53e-07 GO:0008104 protein localization
1.91 3.19e-07 GO:0060548 negative regulation of cell death
1.88 3.62e-07 GO:0010942 positive regulation of cell death
1.86 4.03e-07 GO:0010647 positive regulation of cell communication
2.94 4.71e-07 GO:0030198 extracellular matrix organization
2.37 5.73e-07 GO:0001558 regulation of cell growth
1.85 5.79e-07 GO:0023056 positive regulation of signaling
1.11 7.12e-07 GO:0009987 cellular process
1.92 7.34e-07 GO:0043066 negative regulation of apoptosis
1.93 7.89e-07 GO:0007010 cytoskeleton organization
1.68 9.03e-07 GO:0015031 protein transport
1.95 1.02e-06 GO:0040008 regulation of growth
1.97 1.11e-06 GO:0060284 regulation of cell development
2.18 1.15e-06 GO:0002009 morphogenesis of an epithelium
2.24 1.17e-06 GO:0061061 muscle structure development
2.18 1.56e-06 GO:0001501 skeletal system development
1.89 1.58e-06 GO:0043069 negative regulation of programmed cell death
1.94 1.58e-06 GO:0048666 neuron development
2.07 1.74e-06 GO:0031175 neuron projection development
1.87 1.76e-06 GO:0030030 cell projection organization
2.68 1.80e-06 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.68 1.80e-06 GO:0022604 regulation of cell morphogenesis
1.88 1.93e-06 GO:0032989 cellular component morphogenesis
1.59 1.94e-06 GO:0031324 negative regulation of cellular metabolic process
1.85 2.14e-06 GO:0043068 positive regulation of programmed cell death
1.56 2.56e-06 GO:0010646 regulation of cell communication
1.85 2.86e-06 GO:0043065 positive regulation of apoptosis
1.46 3.10e-06 GO:0065009 regulation of molecular function
1.66 3.23e-06 GO:0048584 positive regulation of response to stimulus
1.56 3.67e-06 GO:0032879 regulation of localization
2.27 4.26e-06 GO:0035239 tube morphogenesis
1.90 4.88e-06 GO:0000902 cell morphogenesis
1.28 5.27e-06 GO:0060255 regulation of macromolecule metabolic process
1.27 5.53e-06 GO:0080090 regulation of primary metabolic process
1.74 6.95e-06 GO:0046907 intracellular transport
2.57 7.45e-06 GO:0014706 striated muscle tissue development
1.54 7.77e-06 GO:0009892 negative regulation of metabolic process
1.79 8.18e-06 GO:0051094 positive regulation of developmental process
1.48 9.47e-06 GO:0010604 positive regulation of macromolecule metabolic process
3.07 9.83e-06 GO:0050679 positive regulation of epithelial cell proliferation
1.51 9.92e-06 GO:0050790 regulation of catalytic activity
1.94 9.98e-06 GO:0090066 regulation of anatomical structure size
1.75 1.12e-05 GO:0065003 macromolecular complex assembly
1.48 1.77e-05 GO:0009056 catabolic process
1.99 1.84e-05 GO:0050767 regulation of neurogenesis
2.33 2.31e-05 GO:0030155 regulation of cell adhesion
1.68 2.41e-05 GO:0019220 regulation of phosphate metabolic process
1.68 2.41e-05 GO:0051174 regulation of phosphorus metabolic process
1.99 2.49e-05 GO:0032535 regulation of cellular component size
2.47 2.79e-05 GO:0001763 morphogenesis of a branching structure
2.35 3.49e-05 GO:0051272 positive regulation of cellular component movement
1.52 4.16e-05 GO:0044248 cellular catabolic process
1.52 4.36e-05 GO:0035556 intracellular signal transduction
1.46 4.44e-05 GO:0031325 positive regulation of cellular metabolic process
1.54 4.46e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.91 4.64e-05 GO:0051960 regulation of nervous system development
1.62 4.91e-05 GO:0031399 regulation of protein modification process
1.69 5.01e-05 GO:0046483 heterocycle metabolic process
2.36 6.38e-05 GO:0030335 positive regulation of cell migration
2.36 6.38e-05 GO:2000147 positive regulation of cell motility
1.30 6.76e-05 GO:0019538 protein metabolic process
1.43 6.82e-05 GO:0006996 organelle organization
1.67 6.82e-05 GO:0042325 regulation of phosphorylation
1.43 6.94e-05 GO:0009893 positive regulation of metabolic process
1.93 7.18e-05 GO:0051130 positive regulation of cellular component organization
2.45 7.72e-05 GO:0042692 muscle cell differentiation
2.55 7.84e-05 GO:0061138 morphogenesis of a branching epithelium
1.87 8.33e-05 GO:0010627 regulation of intracellular protein kinase cascade
1.63 8.52e-05 GO:0016265 death
1.57 8.89e-05 GO:0051649 establishment of localization in cell
3.13 1.01e-04 GO:0048660 regulation of smooth muscle cell proliferation
2.13 1.02e-04 GO:0030029 actin filament-based process
2.04 1.04e-04 GO:0045664 regulation of neuron differentiation
1.68 1.11e-04 GO:0016192 vesicle-mediated transport
1.38 1.12e-04 GO:0042221 response to chemical stimulus
2.23 1.20e-04 GO:0031344 regulation of cell projection organization
1.59 1.26e-04 GO:0044093 positive regulation of molecular function
2.08 1.42e-04 GO:0008361 regulation of cell size
1.62 1.55e-04 GO:0008219 cell death
1.65 1.70e-04 GO:0012501 programmed cell death
1.65 1.70e-04 GO:0043933 macromolecular complex subunit organization
1.32 1.71e-04 GO:0044267 cellular protein metabolic process
2.39 1.75e-04 GO:0048705 skeletal system morphogenesis
1.85 1.81e-04 GO:0051093 negative regulation of developmental process
1.80 1.86e-04 GO:0061024 membrane organization
1.72 1.98e-04 GO:0008284 positive regulation of cell proliferation
1.64 2.24e-04 GO:0043085 positive regulation of catalytic activity
2.25 2.85e-04 GO:0040017 positive regulation of locomotion
2.28 3.66e-04 GO:0010975 regulation of neuron projection development
2.52 3.68e-04 GO:0048754 branching morphogenesis of a tube
1.93 3.83e-04 GO:0000904 cell morphogenesis involved in differentiation
1.64 4.05e-04 GO:0006915 apoptosis
1.55 4.14e-04 GO:0016310 phosphorylation
1.57 4.30e-04 GO:0009890 negative regulation of biosynthetic process
1.37 4.53e-04 GO:0006464 protein modification process
2.01 4.66e-04 GO:0010740 positive regulation of intracellular protein kinase cascade
2.10 4.75e-04 GO:0030036 actin cytoskeleton organization
1.12 5.72e-04 GO:0065007 biological regulation
1.57 5.99e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.69 6.11e-04 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.77 6.33e-04 GO:0016044 cellular membrane organization
2.07 6.49e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.82 6.81e-04 GO:0016477 cell migration
1.48 7.70e-04 GO:0006796 phosphate metabolic process
1.48 8.82e-04 GO:0006793 phosphorus metabolic process
1.57 9.05e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.85 1.04e-03 GO:0031401 positive regulation of protein modification process
1.64 1.08e-03 GO:0001932 regulation of protein phosphorylation
1.74 1.20e-03 GO:0051247 positive regulation of protein metabolic process
1.88 1.25e-03 GO:0045596 negative regulation of cell differentiation
1.86 1.29e-03 GO:0008283 cell proliferation
2.67 1.74e-03 GO:0030879 mammary gland development
2.67 1.74e-03 GO:0045785 positive regulation of cell adhesion
1.76 1.83e-03 GO:0045597 positive regulation of cell differentiation
1.12 1.86e-03 GO:0050789 regulation of biological process
2.04 1.86e-03 GO:0010562 positive regulation of phosphorus metabolic process
2.04 1.86e-03 GO:0045937 positive regulation of phosphate metabolic process
2.18 2.03e-03 GO:0060562 epithelial tube morphogenesis
2.47 2.12e-03 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.22 2.24e-03 GO:0007517 muscle organ development
1.34 2.37e-03 GO:0043412 macromolecule modification
2.42 2.39e-03 GO:0003007 heart morphogenesis
1.78 2.49e-03 GO:0009725 response to hormone stimulus
1.96 2.64e-03 GO:0032269 negative regulation of cellular protein metabolic process
1.73 2.91e-03 GO:0032270 positive regulation of cellular protein metabolic process
2.71 3.04e-03 GO:0051291 protein heterooligomerization
1.55 3.05e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.59 3.12e-03 GO:0007155 cell adhesion
1.59 3.39e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.55 3.60e-03 GO:0010629 negative regulation of gene expression
2.94 3.90e-03 GO:0034330 cell junction organization
1.58 4.00e-03 GO:0051253 negative regulation of RNA metabolic process
1.86 4.00e-03 GO:0009150 purine ribonucleotide metabolic process
1.66 4.16e-03 GO:0044282 small molecule catabolic process
1.72 4.37e-03 GO:0009719 response to endogenous stimulus
4.41 4.53e-03 GO:0010717 regulation of epithelial to mesenchymal transition
1.57 4.70e-03 GO:0022610 biological adhesion
2.46 4.77e-03 GO:0051146 striated muscle cell differentiation
1.77 4.86e-03 GO:0008610 lipid biosynthetic process
1.66 4.92e-03 GO:0006753 nucleoside phosphate metabolic process
1.66 4.92e-03 GO:0009117 nucleotide metabolic process
1.91 4.93e-03 GO:0051248 negative regulation of protein metabolic process
1.59 5.11e-03 GO:0040011 locomotion
2.00 5.24e-03 GO:0042327 positive regulation of phosphorylation
5.51 5.31e-03 GO:0061383 trabecula morphogenesis
1.12 5.44e-03 GO:0050794 regulation of cellular process
1.84 5.45e-03 GO:0009259 ribonucleotide metabolic process
1.87 5.59e-03 GO:0048568 embryonic organ development
2.30 5.71e-03 GO:0051260 protein homooligomerization
1.98 5.91e-03 GO:0051129 negative regulation of cellular component organization
2.14 6.15e-03 GO:0051493 regulation of cytoskeleton organization
1.91 6.86e-03 GO:0048812 neuron projection morphogenesis
1.59 7.68e-03 GO:0071844 cellular component assembly at cellular level
2.19 7.93e-03 GO:0001655 urogenital system development
3.78 8.15e-03 GO:0050673 epithelial cell proliferation
3.98 8.31e-03 GO:0070848 response to growth factor stimulus
1.66 8.78e-03 GO:0051726 regulation of cell cycle
1.66 8.78e-03 GO:0070727 cellular macromolecule localization
1.71 8.87e-03 GO:0072521 purine-containing compound metabolic process
1.46 9.08e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
2.25 9.90e-03 GO:0010720 positive regulation of cell development
2.46 1.07e-02 GO:0070482 response to oxygen levels
1.74 1.09e-02 GO:0006163 purine nucleotide metabolic process
1.66 1.10e-02 GO:0006928 cellular component movement
2.94 1.14e-02 GO:0043627 response to estrogen stimulus
1.65 1.25e-02 GO:0034613 cellular protein localization
1.25 1.25e-02 GO:0010556 regulation of macromolecule biosynthetic process
2.53 1.26e-02 GO:0022612 gland morphogenesis
1.57 1.36e-02 GO:0009605 response to external stimulus
2.38 1.47e-02 GO:0048193 Golgi vesicle transport
1.67 1.51e-02 GO:0048870 cell motility
1.67 1.51e-02 GO:0051674 localization of cell
1.92 1.78e-02 GO:0043193 positive regulation of gene-specific transcription
2.45 1.79e-02 GO:0001666 response to hypoxia
1.45 1.80e-02 GO:0042592 homeostatic process
3.05 1.83e-02 GO:0001936 regulation of endothelial cell proliferation
1.46 1.92e-02 GO:0006629 lipid metabolic process
1.82 2.39e-02 GO:0009144 purine nucleoside triphosphate metabolic process
1.50 2.40e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.82 2.52e-02 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.52 2.59e-02 GO:0042180 cellular ketone metabolic process
2.54 2.84e-02 GO:0010563 negative regulation of phosphorus metabolic process
2.54 2.84e-02 GO:0045936 negative regulation of phosphate metabolic process
1.88 2.85e-02 GO:0032880 regulation of protein localization
1.50 2.93e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
5.29 2.96e-02 GO:0060343 trabecula formation
2.58 3.03e-02 GO:0007519 skeletal muscle tissue development
1.75 3.09e-02 GO:0032990 cell part morphogenesis
1.81 3.18e-02 GO:0009199 ribonucleoside triphosphate metabolic process
1.76 3.29e-02 GO:0048858 cell projection morphogenesis
2.38 3.30e-02 GO:0031346 positive regulation of cell projection organization
2.01 3.30e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.49 3.42e-02 GO:0006468 protein phosphorylation
1.24 3.56e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.71 3.58e-02 GO:0007243 intracellular protein kinase cascade
1.71 3.58e-02 GO:0023014 signal transduction via phosphorylation event
2.41 3.65e-02 GO:0007265 Ras protein signal transduction
2.08 3.94e-02 GO:0008544 epidermis development
1.72 4.10e-02 GO:0044271 cellular nitrogen compound biosynthetic process
1.63 4.11e-02 GO:0048598 embryonic morphogenesis
1.62 4.15e-02 GO:0007417 central nervous system development
1.61 4.18e-02 GO:0044283 small molecule biosynthetic process
2.21 4.23e-02 GO:0030323 respiratory tube development
2.66 4.26e-02 GO:0048738 cardiac muscle tissue development
2.31 4.33e-02 GO:0051640 organelle localization
2.48 4.40e-02 GO:0010721 negative regulation of cell development
1.46 4.55e-02 GO:0055114 oxidation-reduction process
1.22 4.76e-02 GO:0009889 regulation of biosynthetic process
1.83 4.97e-02 GO:0010608 posttranscriptional regulation of gene expression

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.50 3.89e-82 GO:0005737 cytoplasm
1.32 1.03e-63 GO:0005622 intracellular
1.33 9.43e-62 GO:0044424 intracellular part
1.58 9.95e-60 GO:0044444 cytoplasmic part
1.32 7.63e-44 GO:0043226 organelle
1.32 5.51e-43 GO:0043229 intracellular organelle
1.30 4.43e-31 GO:0043227 membrane-bounded organelle
1.30 1.38e-30 GO:0043231 intracellular membrane-bounded organelle
1.14 4.14e-30 GO:0005623 cell
1.14 4.14e-30 GO:0044464 cell part
1.77 4.94e-20 GO:0005856 cytoskeleton
1.40 5.77e-20 GO:0044422 organelle part
1.41 6.35e-20 GO:0044446 intracellular organelle part
1.70 9.12e-17 GO:0005829 cytosol
1.82 3.21e-14 GO:0005794 Golgi apparatus
1.48 5.21e-14 GO:0043228 non-membrane-bounded organelle
1.48 5.21e-14 GO:0043232 intracellular non-membrane-bounded organelle
1.41 2.06e-12 GO:0043234 protein complex
1.77 3.22e-12 GO:0044430 cytoskeletal part
2.40 1.41e-11 GO:0048471 perinuclear region of cytoplasm
1.69 2.89e-11 GO:0005783 endoplasmic reticulum
1.35 5.11e-11 GO:0032991 macromolecular complex
1.63 7.06e-11 GO:0000267 cell fraction
2.39 1.17e-10 GO:0015629 actin cytoskeleton
2.55 3.28e-10 GO:0016323 basolateral plasma membrane
2.24 5.46e-10 GO:0031012 extracellular matrix
1.68 8.42e-10 GO:0044421 extracellular region part
3.01 3.25e-09 GO:0005912 adherens junction
3.47 4.55e-09 GO:0030055 cell-substrate junction
2.82 2.45e-08 GO:0070161 anchoring junction
1.49 2.91e-08 GO:0005739 mitochondrion
2.20 3.32e-08 GO:0044431 Golgi apparatus part
3.40 6.47e-08 GO:0005924 cell-substrate adherens junction
1.67 1.01e-07 GO:0012505 endomembrane system
1.27 1.65e-07 GO:0071944 cell periphery
1.75 2.11e-07 GO:0030054 cell junction
3.35 3.76e-07 GO:0005925 focal adhesion
1.27 4.72e-07 GO:0005886 plasma membrane
1.57 1.54e-06 GO:0005626 insoluble fraction
2.79 1.67e-06 GO:0044420 extracellular matrix part
1.96 1.72e-06 GO:0005625 soluble fraction
2.08 1.74e-06 GO:0005578 proteinaceous extracellular matrix
1.52 1.99e-06 GO:0042995 cell projection
1.39 2.35e-06 GO:0044459 plasma membrane part
2.38 4.41e-06 GO:0031252 cell leading edge
1.47 5.63e-06 GO:0031090 organelle membrane
1.71 8.81e-06 GO:0015630 microtubule cytoskeleton
1.52 5.14e-05 GO:0005624 membrane fraction
2.94 6.40e-05 GO:0005604 basement membrane
1.13 7.24e-05 GO:0016020 membrane
1.62 8.79e-05 GO:0031967 organelle envelope
1.34 1.10e-04 GO:0005576 extracellular region
1.60 1.90e-04 GO:0031975 envelope
1.71 3.50e-04 GO:0005768 endosome
1.17 4.35e-04 GO:0005634 nucleus
1.61 4.63e-04 GO:0043005 neuron projection
1.53 5.50e-04 GO:0005615 extracellular space
1.70 7.60e-04 GO:0044463 cell projection part
1.96 7.99e-04 GO:0005911 cell-cell junction
1.85 9.86e-04 GO:0005773 vacuole
1.64 1.16e-03 GO:0009986 cell surface
4.10 1.81e-03 GO:0009925 basal plasma membrane
2.48 2.70e-03 GO:0016327 apicolateral plasma membrane
3.26 2.78e-03 GO:0005913 cell-cell adherens junction
3.26 2.78e-03 GO:0042641 actomyosin
3.63 4.34e-03 GO:0045178 basal part of cell
1.46 5.08e-03 GO:0031982 vesicle
3.21 6.66e-03 GO:0032432 actin filament bundle
1.70 6.67e-03 GO:0044297 cell body
1.94 1.05e-02 GO:0005635 nuclear envelope
1.82 1.08e-02 GO:0000323 lytic vacuole
1.82 1.08e-02 GO:0005764 lysosome
2.51 1.11e-02 GO:0030426 growth cone
3.23 1.14e-02 GO:0001725 stress fiber
2.02 1.34e-02 GO:0000139 Golgi membrane
2.35 1.69e-02 GO:0043296 apical junction complex
2.42 2.10e-02 GO:0030427 site of polarized growth
1.50 2.25e-02 GO:0044429 mitochondrial part
6.62 2.46e-02 GO:0005915 zonula adherens
2.39 2.57e-02 GO:0030027 lamellipodium
1.70 4.82e-02 GO:0005874 microtubule

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.51 1.27e-47 GO:0005515 protein binding
1.27 3.31e-42 GO:0005488 binding
2.11 5.72e-13 GO:0008092 cytoskeletal protein binding
1.26 7.20e-11 GO:0003824 catalytic activity
1.79 1.73e-10 GO:0042802 identical protein binding
1.68 1.99e-08 GO:0019899 enzyme binding
2.09 1.42e-07 GO:0005525 GTP binding
1.84 2.20e-07 GO:0019904 protein domain specific binding
2.04 2.57e-07 GO:0019001 guanyl nucleotide binding
2.04 2.57e-07 GO:0032561 guanyl ribonucleotide binding
1.42 7.12e-07 GO:0035639 purine ribonucleoside triphosphate binding
1.68 8.24e-07 GO:0046983 protein dimerization activity
2.06 2.18e-06 GO:0003779 actin binding
1.40 2.33e-06 GO:0032553 ribonucleotide binding
1.39 3.40e-06 GO:0032555 purine ribonucleotide binding
1.35 4.06e-06 GO:0000166 nucleotide binding
1.39 5.07e-06 GO:0017076 purine nucleotide binding
2.86 6.19e-06 GO:0019838 growth factor binding
1.87 1.05e-05 GO:0005198 structural molecule activity
1.49 6.10e-05 GO:0005102 receptor binding
1.91 1.57e-04 GO:0019900 kinase binding
2.00 1.71e-04 GO:0019901 protein kinase binding
1.79 4.71e-04 GO:0032403 protein complex binding
1.22 5.31e-04 GO:0043169 cation binding
1.22 6.10e-04 GO:0043167 ion binding
1.67 6.75e-04 GO:0042803 protein homodimerization activity
1.22 1.04e-03 GO:0046872 metal ion binding
1.87 1.17e-03 GO:0046982 protein heterodimerization activity
1.71 1.35e-03 GO:0008289 lipid binding
1.47 2.33e-03 GO:0030234 enzyme regulator activity
1.43 4.68e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.58 5.71e-03 GO:0005509 calcium ion binding
5.88 7.61e-03 GO:0048407 platelet-derived growth factor binding
2.03 1.25e-02 GO:0008022 protein C-terminus binding
1.43 1.50e-02 GO:0016301 kinase activity
3.65 3.09e-02 GO:0005201 extracellular matrix structural constituent
4.20 3.23e-02 GO:0001968 fibronectin binding
1.45 3.72e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.66 3.87e-02 GO:0005178 integrin binding
2.94 3.95e-02 GO:0051219 phosphoprotein binding
4.41 4.93e-02 GO:0031418 L-ascorbic acid binding