• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: TFEB.p2

Z-value: 1.568

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_25211822	48.856	NM_031843	Dpp7	dipeptidylpeptidase 7
chr8_+_13159279	41.831		Lamp1	lysosomal-associated membrane protein 1
chr8_+_13159112	38.763	NM_010684	Lamp1	lysosomal-associated membrane protein 1
chr8_+_3500470	35.916	NM_053177	Mcoln1	mucolipin 1
chr8_+_77617514	34.291	NM_010442	Hmox1	heme oxygenase (decycling) 1
chr7_-_52722144	34.272	NM_007527	Bax	BCL2-associated X protein
chr8_+_77617542	34.208		Hmox1	heme oxygenase (decycling) 1
chrX_-_131135346	34.005	NM_013463	Gla	galactosidase, alpha
chr17_-_12962478	31.547	NM_010515	Igf2r	insulin-like growth factor 2 receptor
chr17_+_25270317	29.919	NM_011930	Clcn7	chloride channel 7
chr6_+_116288073	29.029		March8	membrane-associated ring finger (C3HC4) 8
chr2_+_164659268	28.144		Ctsa	cathepsin A
chr7_-_149573693	27.943	NM_009983	Ctsd	cathepsin D
chrX_+_149574498	27.912	NM_001004154	Rragb	Ras-related GTP binding B
chr6_+_116287992	27.773		March8	membrane-associated ring finger (C3HC4) 8
chr17_-_27076365	26.991	NM_026307 NM_026948	Cuta	cutA divalent cation tolerance homolog (E. coli)
chrX_+_149574541	26.633		Rragb	Ras-related GTP binding B
chr16_-_44139087	25.536	NM_007508	Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A
chr7_-_28338127	25.447	NM_011116	Pld3	phospholipase D family, member 3
chr11_+_119129350	24.937		Gaa	glucosidase, alpha, acid
chr11_-_120494842	24.677	NM_010756	Mafg	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr10_+_120802099	24.379	NM_029364	Gns	glucosamine (N-acetyl)-6-sulfatase
chr6_+_108610606	24.253	NM_011498	Bhlhe40	basic helix-loop-helix family, member e40
chr11_+_29618696	23.816		Rtn4	reticulon 4
chr11_+_119129280	23.435	NM_001159324 NM_008064	Gaa	glucosidase, alpha, acid
chr7_+_109054350	23.318	NM_025605	2400001E08Rik	RIKEN cDNA 2400001E08 gene
chr14_+_63741286	22.765	NM_007798	Ctsb	cathepsin B
chr6_+_116288075	22.647	NM_027920	March8	membrane-associated ring finger (C3HC4) 8
chr17_-_27075896	22.583		Cuta	cutA divalent cation tolerance homolog (E. coli)
chr4_+_123594654	22.544	NM_017475	Rragc	Ras-related GTP binding C
chr10_-_128360523	22.241	NM_015740	Bloc1s1	biogenesis of lysosome-related organelles complex-1, subunit 1
chr5_-_124022937	22.222	NM_029929	Vps33a	vacuolar protein sorting 33A (yeast)
chr8_-_108089811	22.114	NM_013477	Atp6v0d1	ATPase, H+ transporting, lysosomal V0 subunit D1
chr4_+_123594712	21.114		Rragc	Ras-related GTP binding C
chr11_+_102291635	20.814	NM_008175	Grn	granulin
chr4_-_117559857	20.202	NM_033617	Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B
chr14_-_51550327	19.747	NM_001033271	Tmem55b	transmembrane protein 55b
chr13_-_12742377	19.690		Gpr137b-ps Gpr137b	G protein-coupled receptor 137B, pseudogene G protein-coupled receptor 137B
chr4_+_129985957	18.702	NM_010174	Fabp3	fatty acid binding protein 3, muscle and heart
chr13_-_13485585	17.419	NM_031999	Gpr137b	G protein-coupled receptor 137B
chr9_-_91260619	16.948	NM_009573	Zic1	zinc finger protein of the cerebellum 1
chr9_+_58430210	16.822		Nptn	neuroplastin
chr9_-_91260597	16.817		Zic1	zinc finger protein of the cerebellum 1
chr5_+_145016060	16.513	NM_018772	Bri3	brain protein I3
chr16_+_20672847	16.278		Eif4g1	eukaryotic translation initiation factor 4, gamma 1
chrX_-_132706705	16.061	NM_001168578 NM_025703	Tceal8	transcription elongation factor A (SII)-like 8
chr6_+_48986501	15.951	NM_053110	Gpnmb	glycoprotein (transmembrane) nmb
chr11_-_70273453	15.838	NM_023158	Cxcl16	chemokine (C-X-C motif) ligand 16
chrX_-_132749976	15.741	NM_009052	Bex1	brain expressed gene 1
chr6_+_116288396	15.584		March8	membrane-associated ring finger (C3HC4) 8
chr6_-_58857000	15.559	NM_021432	Nap1l5	nucleosome assembly protein 1-like 5
chr11_-_70273434	15.537		Cxcl16	chemokine (C-X-C motif) ligand 16
chr3_-_10208575	15.517	NM_024406	Fabp4	fatty acid binding protein 4, adipocyte
chr11_-_116060026	15.183		Acox1	acyl-Coenzyme A oxidase 1, palmitoyl
chr19_-_41068625	14.789		Blnk	B-cell linker
chr10_+_79167102	14.602	NM_001077184 NM_009768	Bsg	basigin
chr9_+_58430031	14.546	NM_009145	Nptn	neuroplastin
chr6_+_116158049	13.971	NM_026585	D6Wsu116e	DNA segment, Chr 6, Wayne State University 116, expressed
chr14_+_63741339	13.835		Ctsb	cathepsin B
chr17_+_6106829	13.824	NM_001103181	Tulp4	tubby like protein 4
chr13_-_64471609	13.823	NM_009984	Ctsl	cathepsin L
chr6_+_48986625	13.790		Gpnmb	glycoprotein (transmembrane) nmb
chr1_+_90108533	13.700	NM_201645	Ugt1a1	UDP glucuronosyltransferase 1 family, polypeptide A1
chr2_+_83652846	13.589	NM_175514	Fam171b	family with sequence similarity 171, member B
chr9_-_83699706	13.426	NM_001145974 NM_148941	Elovl4	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr17_+_35068258	13.293		Neu1	neuraminidase 1
chr3_+_89006824	13.207	NM_001077411 NM_008094	Gba	glucosidase, beta, acid
chr11_+_55017825	13.051	NM_153139	Slc36a1	solute carrier family 36 (proton/amino acid symporter), member 1
chrX_+_133242520	12.772	NM_146236	Tceal1	transcription elongation factor A (SII)-like 1
chr10_+_12810593	12.735	NM_009538	Plagl1	pleiomorphic adenoma gene-like 1
chr6_+_83745142	12.717	NM_001164187	Nagk	N-acetylglucosamine kinase
chrX_+_78315963	12.640	NM_138751	Tmem47	transmembrane protein 47
chr9_-_86775282	12.639		Snap91	synaptosomal-associated protein 91
chr10_+_77888414	12.627	NM_007793	Cstb	cystatin B
chr1_+_34364633	12.627		Dst	dystonin
chr17_-_25377052	12.601	NM_172529	Gnptg	N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr7_-_28338185	12.532		Pld3	phospholipase D family, member 3
chrX_+_78316003	12.509		Tmem47	transmembrane protein 47
chr17_-_24769511	12.498		Tsc2	tuberous sclerosis 2
chr17_-_24769539	12.416		Tsc2	tuberous sclerosis 2
chr17_-_24300592	12.162	NM_172935	Amdhd2	amidohydrolase domain containing 2
chr7_-_20284370	12.142		Apoe	apolipoprotein E
chr1_+_151947225	12.116	NM_011198	Ptgs2	prostaglandin-endoperoxide synthase 2
chr11_+_54251680	12.018	NM_173753	Fnip1	folliculin interacting protein 1
chr8_-_98377390	11.935	NM_172758	Slc38a7	solute carrier family 38, member 7
chr5_+_138696988	11.836		0910001L09Rik	RIKEN cDNA 0910001L09 gene
chr1_-_82287990	11.780	NM_010570	Irs1	insulin receptor substrate 1
chr1_+_16678536	11.697	NM_001159711 NM_016923	Ly96	lymphocyte antigen 96
chr4_+_61947463	11.649	NM_025286	Slc31a2	solute carrier family 31, member 2
chr11_-_88816679	11.473	NM_029023	Scpep1	serine carboxypeptidase 1
chr13_-_64471562	11.449		Ctsl	cathepsin L
chr7_+_114738722	11.369		Ppfibp2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_-_80522871	11.341	NM_024499	Sgta	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr19_-_7062118	11.266	NM_001185164 NM_011697	Vegfb	vascular endothelial growth factor B
chr5_+_138696947	11.209		0910001L09Rik	RIKEN cDNA 0910001L09 gene
chr1_+_16678513	11.161		Ly96	lymphocyte antigen 96
chr11_+_69804871	11.146	NM_019749	Gabarap	gamma-aminobutyric acid receptor associated protein
chr3_+_89006938	11.110		Gba	glucosidase, beta, acid
chr9_-_86775154	11.083	NM_013669	Snap91	synaptosomal-associated protein 91
chr2_-_30141815	11.074		Dolk	dolichol kinase
chr4_+_147413185	10.960	NM_010840	Mthfr	5,10-methylenetetrahydrofolate reductase
chr4_-_154273134	10.932	NM_025582	2810405K02Rik	RIKEN cDNA 2810405K02 gene
chr15_+_38591604	10.909	NM_025494	Atp6v1c1	ATPase, H+ transporting, lysosomal V1 subunit C1
chr7_-_133520899	10.889		Spns1	spinster homolog 1 (Drosophila)
chrX_+_71542444	10.879		Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1
chr6_+_108733075	10.815		Arl8b	ADP-ribosylation factor-like 8B
chr6_-_108135548	10.814	NM_145937	Sumf1	sulfatase modifying factor 1
chrX_+_33868347	10.777	NM_028894	Lonrf3	LON peptidase N-terminal domain and ring finger 3
chr15_-_89306531	10.754		Arsa	arylsulfatase A
chr12_+_114252715	10.705	NM_001081170	Pacs2	phosphofurin acidic cluster sorting protein 2
chrX_+_133200913	10.661	NM_001029978	Tceal3	transcription elongation factor A (SII)-like 3
chr11_-_70273333	10.552		Cxcl16	chemokine (C-X-C motif) ligand 16
chr11_-_70273251	10.551		Cxcl16	chemokine (C-X-C motif) ligand 16
chr11_-_115948258	10.505	NM_016852	Wbp2	WW domain binding protein 2
chr17_-_34880784	10.496	NM_009780	C4b	complement component 4B (Childo blood group)
chr7_+_16683891	10.454	NM_025898	Napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha
chr16_-_5049999	10.404	NM_001079814 NM_028720	Glyr1	glyoxylate reductase 1 homolog (Arabidopsis)
chrX_+_133200982	10.392		Tceal3	transcription elongation factor A (SII)-like 3
chr11_-_70053281	10.364	NM_173742	Rnasek	ribonuclease, RNase K
chr17_+_33961535	10.318	NM_023202	Ndufa7	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a)
chr12_+_88288287	10.241	NM_173735	2310044G17Rik	RIKEN cDNA 2310044G17 gene
chr3_-_79371600	10.202	NM_001162999	Fnip2	folliculin interacting protein 2
chr15_-_59205688	10.125	NM_153548	E430025E21Rik	RIKEN cDNA E430025E21 gene
chr5_+_89012547	10.051		Rufy3	RUN and FYVE domain containing 3
chr11_+_102291759	9.941		Grn	granulin
chr3_+_67386633	9.832	NM_025813	Mfsd1	major facilitator superfamily domain containing 1
chr11_+_102291828	9.809		Grn	granulin
chr9_-_121404799	9.793	NM_031161	Cck	cholecystokinin
chr18_-_6135887	9.789		Arhgap12	Rho GTPase activating protein 12
chr5_+_30950295	9.783	NM_175675	4930471M23Rik	RIKEN cDNA 4930471M23 gene
chr16_-_45158709	9.755	NM_028756	Slc35a5	solute carrier family 35, member A5
chr3_+_88128944	9.739	NM_020003	0610031J06Rik	RIKEN cDNA 0610031J06 gene
chr17_-_24306262	9.696	NM_009729	Atp6v0c-ps2 Atp6v0c	ATPase, H+ transporting, lysosomal V0 subunit C, pseudogene 2 ATPase, H+ transporting, lysosomal V0 subunit C
chr4_-_86315874	9.687	NM_007408	Plin2	perilipin 2
chr7_-_133520876	9.634		Spns1	spinster homolog 1 (Drosophila)
chr3_+_28680223	9.429	NM_177586	Eif5a2	eukaryotic translation initiation factor 5A2
chr4_+_122513481	9.412	NM_008917	Ppt1	palmitoyl-protein thioesterase 1
chr5_+_137462888	9.333	NM_011962	Plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr8_-_87823373	9.247	NM_022997	Vps35	vacuolar protein sorting 35
chr10_+_79167197	9.225		Bsg	basigin
chrX_-_132602648	8.970	NM_009749	Bex2	brain expressed X-linked 2
chr19_-_6141100	8.921	NM_019722	Arl2	ADP-ribosylation factor-like 2
chr9_+_59387443	8.920	NM_010421	Hexa	hexosaminidase A
chrX_-_34404128	8.913	NM_029951	C330007P06Rik	RIKEN cDNA C330007P06 gene
chr8_-_125135240	8.857	NM_001193645 NM_016722	Galns	galactosamine (N-acetyl)-6-sulfate sulfatase
chr6_+_108733041	8.855	NM_026011	Arl8b	ADP-ribosylation factor-like 8B
chr8_+_36650839	8.848	NM_001081279	Mfhas1	malignant fibrous histiocytoma amplified sequence 1
chrX_+_131291100	8.842	NM_027870	Armcx3	armadillo repeat containing, X-linked 3
chr17_-_34960292	8.808	NM_011413	C4a	complement component 4A (Rodgers blood group)
chr11_-_116060358	8.743	NM_015729	Acox1	acyl-Coenzyme A oxidase 1, palmitoyl
chr11_-_115948206	8.644		Wbp2	WW domain binding protein 2
chr5_+_109098283	8.596		Idua	iduronidase, alpha-L-
chr10_-_126648509	8.550	NM_054097	Pip4k2c	phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr3_+_57539969	8.546	NM_001113413 NM_011883	Rnf13	ring finger protein 13
chr11_-_70273190	8.496		Cxcl16	chemokine (C-X-C motif) ligand 16
chr5_-_31456576	8.453	NM_008622	Mpv17	MpV17 mitochondrial inner membrane protein
chr5_+_89012537	8.395		Rufy3	RUN and FYVE domain containing 3
chrX_+_160346948	8.384	NM_026887	Ap1s2	adaptor-related protein complex 1, sigma 2 subunit
chr15_+_34167908	8.373		Laptm4b	lysosomal-associated protein transmembrane 4B
chr10_+_79167255	8.335		Bsg	basigin
chr3_+_159502646	8.335	NM_026582	Wls	wntless homolog (Drosophila)
chr7_+_134985164	8.327	NM_009294	Stx4a	syntaxin 4A (placental)
chr8_+_125135519	8.251	NM_021502	Trappc2l	trafficking protein particle complex 2-like
chr6_-_87995185	8.246		Rab7	RAB7, member RAS oncogene family
chr5_+_109098381	8.192		Idua	iduronidase, alpha-L-
chr2_-_5816381	8.148	NM_021305	Sec61a2	Sec61, alpha subunit 2 (S. cerevisiae)
chr19_-_7061958	8.137		Vegfb	vascular endothelial growth factor B
chr4_+_128331945	8.088	NM_001195130	Phc2	polyhomeotic-like 2 (Drosophila)
chr12_-_78063011	8.078	NM_001146176 NM_008558	Max	Max protein
chr2_-_30141839	8.077	NM_177648	Dolk	dolichol kinase
chr9_+_70526985	8.067		Adam10	a disintegrin and metallopeptidase domain 10
chr8_-_13890244	8.056	NM_025556	2410022L05Rik	RIKEN cDNA 2410022L05 gene
chr7_+_52104591	8.027	NM_026270	Akt1s1	AKT1 substrate 1 (proline-rich)
chr11_+_100948587	7.995	NM_001159384 NM_001159385 NM_011550	Mlx	MAX-like protein X
chr17_-_56615861	7.963		Ptprs	protein tyrosine phosphatase, receptor type, S
chr12_-_99497498	7.945	NM_008079	Galc	galactosylceramidase
chr7_-_112900699	7.932	NM_009906	Tpp1	tripeptidyl peptidase I
chr16_+_11066390	7.886	NM_009223	Snn	stannin
chr13_+_18809154	7.868	NM_172120	Vps41	vacuolar protein sorting 41 (yeast)
chrX_-_131745187	7.812	NM_025355	Tceal6	transcription elongation factor A (SII)-like 6
chr17_-_46782935	7.778		Klc4	kinesin light chain 4
chr12_+_25659777	7.737	NM_001081378	Kidins220	kinase D-interacting substrate 220
chr3_+_57540000	7.651		Rnf13	ring finger protein 13
chr4_-_147412872	7.618	NM_011929	Clcn6	chloride channel 6
chr4_-_147412919	7.605		Clcn6	chloride channel 6
chr9_-_113617224	7.579	NM_001164677 NM_001164678 NM_011052	Pdcd6ip	programmed cell death 6 interacting protein
chr5_+_118695228	7.552	NM_001081236	2410131K14Rik	RIKEN cDNA 2410131K14 gene
chr10_-_117183413	7.528	NM_029875	Slc35e3	solute carrier family 35, member E3
chr17_+_79451501	7.505		Qpct	glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr6_-_87995010	7.479		Rab7	RAB7, member RAS oncogene family
chr19_+_23215725	7.477		Klf9	Kruppel-like factor 9
chr15_+_54402914	7.446	NM_178920	Mal2	mal, T-cell differentiation protein 2
chr8_-_42459932	7.371	NM_019734	Asah1	N-acylsphingosine amidohydrolase 1
chr5_+_89012596	7.371	NM_027530	Rufy3	RUN and FYVE domain containing 3
chr5_+_137506122	7.318	NM_001039385	Vgf	VGF nerve growth factor inducible
chr1_+_174056868	7.311	NM_001159525 NM_023041	Pex19	peroxisomal biogenesis factor 19
chr5_-_120953567	7.285	NM_023625	Plbd2	phospholipase B domain containing 2
chr8_-_74150754	7.275		Unc13a	unc-13 homolog A (C. elegans)
chr11_+_70658310	7.267		Rabep1	rabaptin, RAB GTPase binding effector protein 1
chr5_+_115461102	7.253		Sppl3	signal peptide peptidase 3

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.00	8.15e-17	GO:0006810	transport
1.89	1.07e-16	GO:0051179	localization
1.97	4.61e-16	GO:0051234	establishment of localization
2.55	1.02e-14	GO:0033036	macromolecule localization
2.68	4.43e-14	GO:0008104	protein localization
2.86	9.45e-13	GO:0015031	protein transport
2.80	3.15e-12	GO:0045184	establishment of protein localization
2.41	4.44e-10	GO:0051641	cellular localization
12.54	1.19e-08	GO:0015682	ferric iron transport
12.54	1.19e-08	GO:0033572	transferrin transport
2.45	1.69e-08	GO:0051649	establishment of localization in cell
13.36	3.12e-08	GO:0015988	energy coupled proton transport, against electrochemical gradient
13.36	3.12e-08	GO:0015991	ATP hydrolysis coupled proton transport
2.61	5.96e-07	GO:0046907	intracellular transport
7.50	5.24e-06	GO:0006826	iron ion transport
2.77	5.25e-06	GO:0034613	cellular protein localization
8.18	6.08e-06	GO:0007033	vacuole organization
2.75	6.43e-06	GO:0070727	cellular macromolecule localization
5.43	8.30e-06	GO:0000041	transition metal ion transport
2.45	1.48e-05	GO:0016192	vesicle-mediated transport
10.72	2.16e-05	GO:0007040	lysosome organization
6.54	3.63e-05	GO:0015992	proton transport
6.43	4.52e-05	GO:0006818	hydrogen transport
1.74	4.99e-05	GO:0065008	regulation of biological quality
2.82	7.02e-05	GO:0044262	cellular carbohydrate metabolic process
2.53	1.05e-04	GO:0005975	carbohydrate metabolic process
2.87	1.87e-04	GO:0006886	intracellular protein transport
1.74	2.28e-04	GO:0044281	small molecule metabolic process
1.52	2.76e-04	GO:0016043	cellular component organization
2.61	1.05e-03	GO:0006066	alcohol metabolic process
1.48	1.29e-03	GO:0071840	cellular component organization or biogenesis
4.17	2.55e-03	GO:0048193	Golgi vesicle transport
6.29	5.76e-03	GO:0006892	post-Golgi vesicle-mediated transport
1.75	6.39e-03	GO:0009056	catabolic process
1.26	7.35e-03	GO:0044237	cellular metabolic process
1.67	1.04e-02	GO:0023051	regulation of signaling
1.23	1.33e-02	GO:0008152	metabolic process
3.24	1.34e-02	GO:0005996	monosaccharide metabolic process
1.14	1.68e-02	GO:0009987	cellular process
2.46	3.34e-02	GO:0009894	regulation of catabolic process
2.60	3.84e-02	GO:0031329	regulation of cellular catabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.59	6.73e-32	GO:0005737	cytoplasm
6.59	8.47e-32	GO:0005773	vacuole
1.80	2.26e-30	GO:0044444	cytoplasmic part
1.39	1.15e-25	GO:0005622	intracellular
6.35	1.06e-24	GO:0000323	lytic vacuole
6.35	1.06e-24	GO:0005764	lysosome
1.39	1.72e-24	GO:0044424	intracellular part
1.46	1.66e-19	GO:0043227	membrane-bounded organelle
1.45	2.27e-19	GO:0043231	intracellular membrane-bounded organelle
1.41	2.40e-19	GO:0043226	organelle
1.40	1.16e-18	GO:0043229	intracellular organelle
1.19	3.86e-15	GO:0005623	cell
1.19	3.86e-15	GO:0044464	cell part
3.44	3.78e-12	GO:0005768	endosome
2.27	4.47e-11	GO:0031090	organelle membrane
16.76	1.37e-09	GO:0033176	proton-transporting V-type ATPase complex
7.66	3.00e-09	GO:0005774	vacuolar membrane
7.14	1.10e-08	GO:0044437	vacuolar part
10.17	4.46e-08	GO:0016469	proton-transporting two-sector ATPase complex
1.85	3.01e-06	GO:0005829	cytosol
16.88	1.17e-05	GO:0016471	vacuolar proton-transporting V-type ATPase complex
2.16	2.15e-05	GO:0031982	vesicle
4.78	2.53e-05	GO:0005769	early endosome
2.12	2.97e-05	GO:0012505	endomembrane system
1.42	3.01e-05	GO:0044446	intracellular organelle part
2.17	4.17e-05	GO:0031410	cytoplasmic vesicle
5.23	4.24e-05	GO:0005770	late endosome
2.35	6.39e-05	GO:0031988	membrane-bounded vesicle
1.86	7.34e-05	GO:0000267	cell fraction
1.40	7.74e-05	GO:0044422	organelle part
2.37	1.03e-04	GO:0016023	cytoplasmic membrane-bounded vesicle
12.66	1.50e-04	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
1.23	1.51e-04	GO:0016020	membrane
4.33	2.43e-04	GO:0010008	endosome membrane
4.33	2.43e-04	GO:0044440	endosomal part
20.67	2.91e-04	GO:0033180	proton-transporting V-type ATPase, V1 domain
1.87	9.60e-04	GO:0005794	Golgi apparatus
1.76	2.34e-03	GO:0042995	cell projection
1.76	4.26e-03	GO:0005783	endoplasmic reticulum
19.30	6.07e-03	GO:0033179	proton-transporting V-type ATPase, V0 domain
1.80	8.01e-03	GO:0005624	membrane fraction
1.75	1.40e-02	GO:0005626	insoluble fraction
1.98	1.57e-02	GO:0043005	neuron projection
5.79	1.70e-02	GO:0042734	presynaptic membrane
2.97	1.94e-02	GO:0030135	coated vesicle
14.47	2.68e-02	GO:0042599	lamellar body
4.26	3.26e-02	GO:0031227	intrinsic to endoplasmic reticulum membrane
6.14	3.36e-02	GO:0005765	lysosomal membrane
2.63	3.71e-02	GO:0030141	stored secretory granule
5.15	4.09e-02	GO:0005905	coated pit
9.05	4.67e-02	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain
12.86	4.69e-02	GO:0030132	clathrin coat of coated pit
12.86	4.69e-02	GO:0030669	clathrin-coated endocytic vesicle membrane
2.86	4.84e-02	GO:0044433	cytoplasmic vesicle part
3.75	4.87e-02	GO:0005802	trans-Golgi network

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.45	3.53e-10	GO:0005515	protein binding
1.20	1.66e-05	GO:0005488	binding
5.20	1.69e-04	GO:0015078	hydrogen ion transmembrane transporter activity
5.60	4.93e-04	GO:0042625	ATPase activity, coupled to transmembrane movement of ions
4.43	5.53e-04	GO:0015399	primary active transmembrane transporter activity
4.43	5.53e-04	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity
13.36	9.85e-04	GO:0046961	proton-transporting ATPase activity, rotational mechanism
4.50	1.02e-03	GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
4.50	1.02e-03	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
4.36	1.52e-03	GO:0043492	ATPase activity, coupled to movement of substances
12.40	1.67e-03	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism
2.55	3.68e-03	GO:0022804	active transmembrane transporter activity
1.88	1.62e-02	GO:0046983	protein dimerization activity
2.50	1.64e-02	GO:0046982	protein heterodimerization activity
8.27	2.46e-02	GO:0019829	cation-transporting ATPase activity
1.76	3.45e-02	GO:0019899	enzyme binding