Motif ID: UGCAUUG

Z-value: 0.772


Mature miRNA associated with seed UGCAUUG:

NamemiRBase Accession
mmu-miR-33 MIMAT0000667



Activity profile for motif UGCAUUG.

activity profile for motif UGCAUUG


Sorted Z-values histogram for motif UGCAUUG

Sorted Z-values for motif UGCAUUG



Network of associatons between targets according to the STRING database.



First level regulatory network of UGCAUUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_164793487 23.094 NM_020333
Slc12a5
solute carrier family 12, member 5
chr17_+_25945986 13.839 NM_001164225
Fbxl16
F-box and leucine-rich repeat protein 16
chr3_-_84024766 13.461 NM_030706
Trim2
tripartite motif-containing 2
chr15_+_100701068 13.325 NM_001077499
Scn8a
sodium channel, voltage-gated, type VIII, alpha
chr15_+_100766701 12.863 NM_011323
Scn8a
sodium channel, voltage-gated, type VIII, alpha
chr5_+_130845319 12.300 NM_181045
Caln1
calneuron 1
chr5_+_130924661 10.938 NM_021371
Caln1
calneuron 1
chr13_-_105844882 10.923 NM_029879
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr6_+_71657791 10.379 NM_178608
Reep1
receptor accessory protein 1
chr1_-_25886551 9.926 NM_175642
Bai3
brain-specific angiogenesis inhibitor 3
chr6_-_92517359 9.386 NM_001134461
Prickle2
prickle homolog 2 (Drosophila)
chr6_-_92656148 9.176 NM_001081146
Prickle2
prickle homolog 2 (Drosophila)
chr7_-_148615247 8.618 NM_021316
Cend1
cell cycle exit and neuronal differentiation 1
chr6_-_92484838 8.535 NM_001134459
Prickle2
prickle homolog 2 (Drosophila)
chr11_-_103815361 8.263 NM_008740
Nsf
N-ethylmaleimide sensitive fusion protein
chr9_-_56533004 8.262 NM_181074
Lingo1
leucine rich repeat and Ig domain containing 1
chr17_-_64681166 8.227 NM_001025309
NM_144859
Pja2

praja 2, RING-H2 motif containing

chr6_-_92431385 8.149 NM_001134460
Prickle2
prickle homolog 2 (Drosophila)
chr19_-_58935470 7.879 NM_175199
Hspa12a
heat shock protein 12A
chr3_-_81949667 7.288 NM_021896
Gucy1a3
guanylate cyclase 1, soluble, alpha 3
chr7_+_94732677 7.196 NM_001081414
NM_001143834
Grm5

glutamate receptor, metabotropic 5

chr1_-_77511653 7.148 NM_007936
Epha4
Eph receptor A4
chr9_-_54349409 6.941 NM_172771
Dmxl2
Dmx-like 2
chr2_+_138104219 6.877 NM_145534
Btbd3
BTB (POZ) domain containing 3
chr2_+_138082301 6.797 NM_001025431
Btbd3
BTB (POZ) domain containing 3
chr3_-_26052228 6.751 NM_001163387
Nlgn1
neuroligin 1
chr12_-_14158843 6.706 NM_029007
Fam84a
family with sequence similarity 84, member A
chr3_+_64913564 6.685 NM_010597
Kcnab1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr3_-_26230791 6.669 NM_138666
Nlgn1
neuroligin 1
chr10_+_4424140 6.520 NM_001161822
NM_019958
Rgs17

regulator of G-protein signaling 17

chr2_+_156246644 6.240 NM_001003815
NM_013510
Epb4.1l1

erythrocyte protein band 4.1-like 1

chr16_-_67621054 6.110 NM_001145977
NM_178721
Cadm2

cell adhesion molecule 2

chr10_-_49508472 6.066 NM_001111268
NM_010349
Grik2

glutamate receptor, ionotropic, kainate 2 (beta 2)

chr13_+_118391126 6.012 NM_010408
Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr19_+_38339167 5.887 NM_020278
Lgi1
leucine-rich repeat LGI family, member 1
chr6_+_4853319 5.880 NM_181595
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr13_+_109444370 5.824 NM_011056
Pde4d
phosphodiesterase 4D, cAMP specific
chr6_-_28781687 5.451 NM_138682
Lrrc4
leucine rich repeat containing 4
chr5_-_71233855 5.038 NM_010252
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr12_+_25516433 4.758 NM_001083341
NM_026037
Mboat2

membrane bound O-acyltransferase domain containing 2

chr3_+_5218545 4.628 NM_030708
Zfhx4
zinc finger homeodomain 4
chr2_+_156301543 4.547 NM_001006664
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr6_-_119058206 4.526 NM_001159533
NM_001159534
NM_001159535
Cacna1c


calcium channel, voltage-dependent, L type, alpha 1C subunit


chr6_-_119146426 4.419 NM_009781
Cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr18_+_57292743 4.382 NM_001001979
Megf10
multiple EGF-like-domains 10
chr2_+_35477498 4.354 NM_001114124
Dab2ip
disabled homolog 2 (Drosophila) interacting protein
chr2_+_35547418 3.977 NM_001001602
Dab2ip
disabled homolog 2 (Drosophila) interacting protein
chrX_+_20265590 3.706 NM_011049
Cdk16
cyclin-dependent kinase 16
chr7_+_129432585 3.528 NM_008855
Prkcb
protein kinase C, beta
chr2_+_76244578 3.349 NM_145525
Osbpl6
oxysterol binding protein-like 6
chr14_-_31304341 3.327 NM_028981
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr2_-_32306938 3.263 NM_001164357
NM_146118
Slc25a25

solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25

chr2_-_134469806 3.199 NM_029148
Tmx4
thioredoxin-related transmembrane protein 4
chr4_-_8166182 3.195 NM_007592
Car8
carbonic anhydrase 8
chr6_-_149050201 3.140 NM_177192
Dennd5b
DENN/MADD domain containing 5B
chr1_+_120285634 3.118 NM_001081276
NM_029709
NM_177548
Clasp1


CLIP associating protein 1


chr2_-_32286633 3.050 NM_001164358
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr4_-_53172748 2.901 NM_013454
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr8_+_113443764 2.757 NM_009179
St3gal2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr11_-_29147217 2.630 NM_025740
Ccdc104
coiled-coil domain containing 104
chr3_-_107499460 2.581 NM_145542
Ahcyl1
S-adenosylhomocysteine hydrolase-like 1
chrX_+_38754480 2.578 NM_016886
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr2_+_35413977 2.531 NM_001114125
Dab2ip
disabled homolog 2 (Drosophila) interacting protein
chr4_+_13711928 2.525 NM_009822
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_74416925 2.523 NM_001110209
NM_027133
Lnp

limb and neural patterns

chr15_-_81846328 2.456 NM_134095
Pppde2
PPPDE peptidase domain containing 2
chr9_-_101154160 2.436 NM_001161362
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr1_-_58642994 2.358 NM_172513
Fam126b
family with sequence similarity 126, member B
chr5_+_34916343 2.354 NM_001024458
NM_001102444
NM_013457
Add1


adducin 1 (alpha)


chr14_+_47621014 2.344 NM_001163433
Samd4
sterile alpha motif domain containing 4
chr2_-_37502738 2.293 NM_009261
Strbp
spermatid perinuclear RNA binding protein
chr10_-_126648509 2.259 NM_054097
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr3_-_115956312 2.244 NM_022427
Gpr88
G-protein coupled receptor 88
chr4_+_84530230 2.111 NM_175275
NM_177385
Cntln

centlein, centrosomal protein

chr3_-_116510948 2.089 NM_001081326
Agl
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr4_+_97444312 2.083 NM_001122953
NM_010905
Nfia

nuclear factor I/A

chr4_+_13670425 2.033 NM_001111026
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr14_-_21613162 1.968 NM_001039138
NM_001039139
NM_178597
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr19_-_37281762 1.905 NM_198300
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr6_-_38787222 1.883 NM_001136065
Hipk2
homeodomain interacting protein kinase 2
chr6_-_28084368 1.828 NM_008174
Grm8
glutamate receptor, metabotropic 8
chr5_+_43624701 1.725 NM_001177379
NM_175937
Cpeb2

cytoplasmic polyadenylation element binding protein 2

chr11_+_115243203 1.603 NM_001080929
Cdr2l
cerebellar degeneration-related protein 2-like
chr4_-_148001104 1.583 NM_001003898
NM_001003899
NM_001008545
NM_001008546
NM_145556
Tardbp




TAR DNA binding protein




chr2_-_7002344 1.557 NM_001110229
NM_001110230
NM_001160292
Celf2


CUGBP, Elav-like family member 2


chr11_+_105451296 1.523 NM_181071
Tanc2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr19_+_43514902 1.451 NM_031396
Cnnm1
cyclin M1
chr6_+_65621583 1.403 NM_172399
A930038C07Rik
RIKEN cDNA A930038C07 gene
chr5_+_58109246 1.389 NM_001122758
NM_018764
Pcdh7

protocadherin 7

chr15_+_88692581 1.324 NM_145478
Pim3
proviral integration site 3
chr1_+_174078145 1.309 NM_153555
Dcaf8
DDB1 and CUL4 associated factor 8
chr5_-_69732915 1.192 NM_175519
Kctd8
potassium channel tetramerisation domain containing 8
chr9_-_101101334 1.190 NM_172144
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr8_-_97400173 1.135 NM_053246
Dok4
docking protein 4
chr11_+_67508827 1.066 NM_009038
Rcvrn
recoverin
chr7_+_80520360 1.052 NM_177740
Rgma
RGM domain family, member A
chr11_-_84953442 1.051 NM_001029934
Usp32
ubiquitin specific peptidase 32
chr6_-_56312803 1.042 NM_001159960
Pde1c
phosphodiesterase 1C
chr14_+_21493519 1.020 NM_001168273
NM_172596
Sec24c

Sec24 related gene family, member C (S. cerevisiae)

chr14_-_31166671 1.011 NM_001083616
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr12_-_109241423 0.914 NM_001079883
NM_021399
Bcl11b

B-cell leukemia/lymphoma 11B

chr3_+_135488454 0.817 NM_026228
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr2_-_7317513 0.811 NM_001110232
Celf2
CUGBP, Elav-like family member 2
chr9_-_42280256 0.782 NM_173038
Tbcel
tubulin folding cofactor E-like
chr19_+_38911056 0.760 NM_145952
Tbc1d12
TBC1D12: TBC1 domain family, member 12
chr8_-_74009902 0.729 NM_001164679
Ano8
anoctamin 8
chr3_-_92674126 0.713 NM_025621
2310050C09Rik
RIKEN cDNA 2310050C09 gene
chr10_-_13194201 0.687 NM_001195065
Phactr2
phosphatase and actin regulator 2
chr9_+_65478364 0.584 NM_028030
Rbpms2
RNA binding protein with multiple splicing 2
chr11_-_45979836 0.563 NM_172524
Nipal4
NIPA-like domain containing 4
chr14_+_47502637 0.527 NM_001037221
NM_028966
Samd4

sterile alpha motif domain containing 4

chr6_-_56319574 0.526 NM_001159955
NM_001159956
NM_001159957
Pde1c


phosphodiesterase 1C


chr17_-_91492065 0.511 NM_020252
NM_177284
Nrxn1

neurexin I

chr5_-_90312358 0.509 NM_001081401
NM_177872
Adamts3

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3

chr5_+_111308801 0.469 NM_024477
Ttc28
tetratricopeptide repeat domain 28
chr10_+_98725858 0.465 NM_026268
Dusp6
dual specificity phosphatase 6
chr17_+_29169579 0.435 NM_013663
Srsf3
serine/arginine-rich splicing factor 3
chr6_-_56312170 0.402 NM_001025568
NM_001159952
NM_001159953
NM_011054
Pde1c



phosphodiesterase 1C



chr2_-_7317824 0.350 NM_001110231
Celf2
CUGBP, Elav-like family member 2
chr16_+_95923988 0.339 NM_011809
Ets2
E26 avian leukemia oncogene 2, 3' domain
chr17_-_24278482 0.305 NM_001080773
NM_011062
Pdpk1

3-phosphoinositide dependent protein kinase 1

chr5_+_13399301 0.295 NM_009152
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_52290058 0.234 NM_001081081
NM_001113383
Gls

glutaminase

chr1_-_80210403 0.228 NM_173425
Fam124b
family with sequence similarity 124, member B
chr9_-_78329444 0.222 NM_010106
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr7_+_54305973 0.152 NM_026436
Tmem86a
transmembrane protein 86A
chr6_-_38826156 0.120 NM_010433
Hipk2
homeodomain interacting protein kinase 2
chr1_+_181891219 0.098 NM_001033285
Cdc42bpa
CDC42 binding protein kinase alpha
chr2_+_90687308 0.049 NM_019758
Mtch2
mitochondrial carrier homolog 2 (C. elegans)
chr13_-_60278859 0.008 NM_008086
Gas1
growth arrest specific 1
chr11_+_35582969 0.003 NM_145962
Pank3
pantothenate kinase 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.42 5.60e-05 GO:0006811 ion transport
5.75 5.06e-03 GO:0019226 transmission of nerve impulse
5.75 5.06e-03 GO:0035637 multicellular organismal signaling
4.68 5.10e-03 GO:0030001 metal ion transport
6.54 5.22e-03 GO:0007268 synaptic transmission
24.16 1.15e-02 GO:0007628 adult walking behavior
4.00 2.40e-02 GO:0006812 cation transport

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
6.29 4.71e-07 GO:0045202 synapse
2.28 3.12e-06 GO:0071944 cell periphery
2.22 1.71e-05 GO:0005886 plasma membrane
6.75 2.16e-05 GO:0044456 synapse part
7.23 3.64e-05 GO:0030425 dendrite
2.83 8.83e-05 GO:0044459 plasma membrane part
4.73 1.48e-04 GO:0043005 neuron projection
8.15 2.56e-03 GO:0045211 postsynaptic membrane
3.03 3.96e-03 GO:0042995 cell projection
19.71 5.11e-03 GO:0043198 dendritic shaft
18.73 6.28e-03 GO:0042734 presynaptic membrane
4.57 6.93e-03 GO:0044463 cell projection part
3.69 1.00e-02 GO:0030054 cell junction
4.66 3.39e-02 GO:0043025 neuronal cell body
6.43 3.64e-02 GO:0034702 ion channel complex
1.43 3.96e-02 GO:0016020 membrane
4.44 4.68e-02 GO:0044297 cell body

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
25.83 2.20e-03 GO:0008066 glutamate receptor activity
6.07 2.37e-03 GO:0022836 gated channel activity
5.14 3.36e-03 GO:0005216 ion channel activity
5.03 4.04e-03 GO:0022838 substrate-specific channel activity
4.87 5.28e-03 GO:0015267 channel activity
4.86 5.40e-03 GO:0022803 passive transmembrane transporter activity
3.75 5.48e-03 GO:0015075 ion transmembrane transporter activity
2.29 7.43e-03 GO:0000166 nucleotide binding
8.58 9.67e-03 GO:0022843 voltage-gated cation channel activity
29.56 1.81e-02 GO:0030552 cAMP binding
3.26 2.25e-02 GO:0022891 substrate-specific transmembrane transporter activity