Motif ID: UUUUUGC

Z-value: 1.285


Mature miRNA associated with seed UUUUUGC:

NamemiRBase Accession
mmu-miR-129-5p MIMAT0000209



Activity profile for motif UUUUUGC.

activity profile for motif UUUUUGC


Sorted Z-values histogram for motif UUUUUGC

Sorted Z-values for motif UUUUUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUUUUGC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_9725274 21.478 NM_181850
Grm3
glutamate receptor, metabotropic 3
chrX_-_49034778 19.984 NM_001077202
Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr16_+_5884885 19.788 NM_021477
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chrX_-_49033640 19.293 NM_015819
Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr16_+_7069927 17.802 NM_183188
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr18_-_25912453 17.113 NM_001146292
NM_001146293
NM_001146294
NM_001146295
NM_001174074
NM_133195
Celf4





CUGBP, Elav-like family member 4





chr15_+_91958558 16.946 NM_007727
Cntn1
contactin 1
chr15_+_91881593 16.711 NM_001159648
Cntn1
contactin 1
chr5_-_145522423 14.246 NM_177735
Tmem130
transmembrane protein 130
chr15_+_91991704 13.774 NM_001159647
Cntn1
contactin 1
chr16_-_91011339 13.661 NM_001045515
NM_001164483
Synj1

synaptojanin 1

chr2_-_52532100 13.595 NM_001037099
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr11_-_41996141 13.592 NM_010250
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr2_-_148558110 13.512 NM_019632
Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr2_-_52414072 13.210 NM_146123
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr10_+_75716580 13.177 NM_009115
S100b
S100 protein, beta polypeptide, neural
chr1_+_66515003 12.896 NM_175510
Unc80
unc-80 homolog (C. elegans)
chr16_+_38089086 12.578 NM_019827
Gsk3b
glycogen synthase kinase 3 beta
chr7_+_4071087 10.622 NM_001001454
NM_001109765
NM_021324
Ttyh1


tweety homolog 1 (Drosophila)


chr6_+_7505070 10.597 NM_009311
Tac1
tachykinin 1
chr14_-_80171003 10.491 NM_001042726
NM_021543
Pcdh8

protocadherin 8

chr3_-_80606704 9.936 NM_001039195
NM_001083806
NM_013540
Gria2


glutamate receptor, ionotropic, AMPA2 (alpha 2)


chr6_+_21166108 9.744 NM_019697
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr8_-_9771020 9.732 NM_173446
Fam155a
family with sequence similarity 155, member A
chr4_-_151235861 9.343 NM_001081557
NM_001195565
Camta1

calmodulin binding transcription activator 1

chr18_-_35374663 9.223 NM_178005
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr2_-_7002344 9.115 NM_001110229
NM_001110230
NM_001160292
Celf2


CUGBP, Elav-like family member 2


chr1_-_23389950 8.852 NM_001081079
Ogfrl1
opioid growth factor receptor-like 1
chr4_-_75779379 8.475 NM_001014288
Ptprd
protein tyrosine phosphatase, receptor type, D
chr2_+_158492468 8.272 NM_153089
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr13_-_14615371 7.900 NM_001081348
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr3_-_117063793 7.839 NM_177664
D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr13_+_58907953 7.825 NM_008745
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr10_+_89336253 7.559 NM_001128086
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_+_106708886 7.387 NM_001033223
NM_001039354
Lin7a

lin-7 homolog A (C. elegans)

chr12_+_86814822 7.336 NM_010234
Fos
FBJ osteosarcoma oncogene
chr4_-_76240202 7.267 NM_011211
Ptprd
protein tyrosine phosphatase, receptor type, D
chr2_-_104250490 7.051 NM_001033347
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr7_-_89079335 6.968 NM_013886
Hdgfrp3
hepatoma-derived growth factor, related protein 3
chr2_-_66278870 6.853 NM_018733
Scn1a
sodium channel, voltage-gated, type I, alpha
chr5_+_151476361 6.838 NM_175310
Pds5b
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr7_-_38554642 6.760 NM_172385
Zfp536
zinc finger protein 536
chr4_+_108551674 6.760 NM_023537
Rab3b
RAB3B, member RAS oncogene family
chr14_+_84843366 6.564 NM_001013753
Pcdh17
protocadherin 17
chr5_+_22252006 6.532 NM_001081231
NM_029990
Lhfpl3

lipoma HMGIC fusion partner-like 3

chr2_-_7317513 6.515 NM_001110232
Celf2
CUGBP, Elav-like family member 2
chr6_+_96063137 6.376 NM_182808
Fam19a1
family with sequence similarity 19, member A1
chr4_+_137806293 6.360 NM_001099631
Sh2d5
SH2 domain containing 5
chr2_+_164313584 6.343 NM_001048229
Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr3_-_59066744 6.223 NM_027571
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr2_+_164312376 6.145 NM_001048228
Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr18_-_16967557 6.109 NM_007664
Cdh2
cadherin 2
chr6_+_54402876 6.075 NM_001167860
NM_001167861
Wipf3

WAS/WASL interacting protein family, member 3

chr18_+_65183180 6.031 NM_031881
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr4_+_34011567 6.028 NM_007726
Cnr1
cannabinoid receptor 1 (brain)
chrX_+_147778717 5.992 NM_198105
Fam120c
family with sequence similarity 120, member C
chr10_+_90038471 5.942 NM_001177397
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr2_-_7317824 5.905 NM_001110231
Celf2
CUGBP, Elav-like family member 2
chr10_-_62342761 5.793 NM_027384
Tet1
tet oncogene 1
chr7_-_88837850 5.785 NM_001164087
Homer2
homer homolog 2 (Drosophila)
chrX_+_160346948 5.768 NM_026887
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr7_-_147340532 5.752 NM_183147
Sprn
shadow of prion protein
chr4_+_155367019 5.745 NM_011341
Sdf4
stromal cell derived factor 4
chr4_-_107973683 5.728 NM_001033634
Zyg11b
zyg-ll homolog B (C. elegans)
chr2_+_121115337 5.711 NM_032393
Mtap1a
microtubule-associated protein 1 A
chr10_-_42894259 5.643 NM_175407
Sobp
sine oculis-binding protein homolog (Drosophila)
chr4_-_154735351 5.638 NM_008860
Prkcz
protein kinase C, zeta
chr4_-_154719834 5.587 NM_001039079
Prkcz
protein kinase C, zeta
chr10_+_90039435 5.570 NM_001177396
NM_001177398
NM_181398
Ipw
Anks1b


imprinted gene in the Prader-Willi syndrome region
ankyrin repeat and sterile alpha motif domain containing 1B


chr4_+_17780628 5.531 NM_019724
Mmp16
matrix metallopeptidase 16
chr2_-_77654669 5.468 NM_178723
Zfp385b
zinc finger protein 385B
chr17_+_93598761 5.355 NM_009625
Adcyap1
adenylate cyclase activating polypeptide 1
chr9_-_113935832 5.297 NM_178624
Fbxl2
F-box and leucine-rich repeat protein 2
chr2_+_19579607 5.283 NM_027715
Otud1
OTU domain containing 1
chr5_-_123214252 5.226 NM_145358
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr2_+_121121189 5.218 NM_001173506
Mtap1a
microtubule-associated protein 1 A
chr12_+_53800369 5.199 NM_198111
Akap6
A kinase (PRKA) anchor protein 6
chr10_+_4424140 5.155 NM_001161822
NM_019958
Rgs17

regulator of G-protein signaling 17

chr7_-_149276174 5.151 NM_008748
Dusp8
dual specificity phosphatase 8
chr2_+_164311639 5.119 NM_001048227
Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr13_+_109004589 5.055 NM_029001
Elovl7
ELOVL family member 7, elongation of long chain fatty acids (yeast)
chr14_+_76354807 4.982 NM_026214
Kctd4
potassium channel tetramerisation domain containing 4
chr1_+_87791084 4.937 NM_022417
Itm2c
integral membrane protein 2C
chr1_-_16646922 4.829 NM_026456
Tceb1
transcription elongation factor B (SIII), polypeptide 1
chr9_-_105034128 4.753 NM_029385
Nudt16
nudix (nucleoside diphosphate linked moiety X)-type motif 16
chr10_+_110601745 4.749 NM_001003717
NM_175489
Osbpl8

oxysterol binding protein-like 8

chr17_-_23330163 4.726 NM_009555
Zfp40
zinc finger protein 40
chrX_-_133403050 4.695 NM_176971
Rab9b
RAB9B, member RAS oncogene family
chr3_+_84619399 4.650 NM_001177773
Fbxw7
F-box and WD-40 domain protein 7
chr2_+_164311755 4.558 NM_026797
Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr3_+_84668066 4.528 NM_001177774
Fbxw7
F-box and WD-40 domain protein 7
chr14_-_62175657 4.527 NM_025697
6330409N04Rik
RIKEN cDNA 6330409N04 gene
chrX_-_34442878 4.409 NM_029891
Nkrf
NF-kappaB repressing factor
chr12_-_36769054 4.375 NM_025359
Tspan13
tetraspanin 13
chr1_+_194014677 4.328 NM_001038607
NM_010600
Kcnh1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr18_+_65047408 4.294 NM_001114386
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr7_-_88851798 4.293 NM_001164086
NM_011983
Homer2

homer homolog 2 (Drosophila)

chr7_+_107756069 4.186 NM_001163663
NM_024287
Rab6

RAB6, member RAS oncogene family

chr7_-_88974235 4.179 NM_146193
Btbd1
BTB (POZ) domain containing 1
chr12_+_4134152 4.073 NM_138305
Adcy3
adenylate cyclase 3
chr12_+_4133370 3.933 NM_001159536
NM_001159537
Adcy3

adenylate cyclase 3

chr2_-_77541328 3.867 NM_001113399
Zfp385b
zinc finger protein 385B
chr6_+_21899614 3.823 NM_023626
Ing3
inhibitor of growth family, member 3
chr2_+_158492854 3.810 NM_001159662
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr2_+_112106470 3.798 NM_133649
Slc12a6
solute carrier family 12, member 6
chr4_+_32504409 3.781 NM_001109661
Bach2
BTB and CNC homology 2
chr18_-_67708826 3.741 NM_176832
Spire1
spire homolog 1 (Drosophila)
chr3_+_102538692 3.739 NM_027533
Tspan2
tetraspanin 2
chr5_+_136108487 3.724 NM_146002
Rhbdd2
rhomboid domain containing 2
chr12_-_100139666 3.707 NM_001081191
Eml5
echinoderm microtubule associated protein like 5
chr2_-_6805937 3.670 NM_001110228
NM_001160293
NM_010160
Celf2


CUGBP, Elav-like family member 2


chr9_+_43892984 3.668 NM_198091
Usp2
ubiquitin specific peptidase 2
chr2_+_109533719 3.653 NM_001048142
Bdnf
brain derived neurotrophic factor
chr5_-_51945054 3.651 NM_008904
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr8_-_63462080 3.547 NM_007711
NM_173873
NM_173874
Clcn3


chloride channel 3


chr17_+_33226311 3.546 NM_001024950
Zfp563
zinc finger protein 563
chrX_+_99044723 3.541 NM_001163610
Nhsl2
NHS-like 2
chr9_-_20297116 3.515 NM_001110309
NM_146221
Zfp426

zinc finger protein 426

chr19_-_34676457 3.479 NM_001101605
Gm14446
predicted gene 14446
chr1_+_95240200 3.475 NM_023200
Ppp1r7
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr19_-_34673889 3.428 NM_001110517
Gm14446
predicted gene 14446
chr1_-_107253245 3.419 NM_001160368
NM_178779
Rnf152

ring finger protein 152

chr13_-_91363591 3.399 NM_025770
Atg10
autophagy-related 10 (yeast)
chr18_-_67712374 3.393 NM_194355
Spire1
spire homolog 1 (Drosophila)
chr2_+_150043834 3.347 NM_001142411
Zfp937
zinc finger protein 937
chr2_-_24830511 3.280 NM_001031808
Mrpl41
mitochondrial ribosomal protein L41
chr19_+_26679649 3.269 NM_011416
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_55462764 3.196 NM_001114663
Plcl1
phospholipase C-like 1
chr17_+_42452895 3.185 NM_028474
3110082D06Rik
RIKEN cDNA 3110082D06 gene
chr5_-_139060952 3.173 NM_001044747
NM_001163797
NM_013844
Zfp68


zinc finger protein 68


chr13_+_115608425 3.167 NM_001113374
NM_001113375
NM_013826
Mocs2


molybdenum cofactor synthesis 2


chr12_-_101963226 3.166 NM_153587
Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr12_+_31269290 3.161 NM_172049
Tmem18
transmembrane protein 18
chr12_-_40764554 3.159 NM_001039515
Arl4a
ADP-ribosylation factor-like 4A
chr6_-_52859613 3.101 NM_001168277
Jazf1
JAZF zinc finger 1
chr18_+_65590615 3.068 NM_172833
Malt1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr12_+_37040755 3.047 NM_025312
Sostdc1
sclerostin domain containing 1
chr2_-_77357674 3.044 NM_001113400
Zfp385b
zinc finger protein 385B
chrX_+_46823626 3.023 NM_001081123
Arhgap36
Rho GTPase activating protein 36
chrX_-_83021840 2.965 NM_008194
NM_212444
Gyk

glycerol kinase

chr7_-_4014717 2.953 NM_001113474
NM_178611
Lair1

leukocyte-associated Ig-like receptor 1

chr2_+_163820920 2.935 NM_018753
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr6_+_48345584 2.926 NM_133922
4930447G04Rik
Krba1
RIKEN cDNA 4930447G04 gene
KRAB-A domain containing 1
chr4_+_108952859 2.914 NM_007943
Eps15
epidermal growth factor receptor pathway substrate 15
chr12_-_80273320 2.912 NM_016800
Vti1b
vesicle transport through interaction with t-SNAREs 1B homolog
chr14_+_77556622 2.903 NM_172813
Enox1
ecto-NOX disulfide-thiol exchanger 1
chr9_+_81757308 2.892 NM_175213
Mei4
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr4_+_114732112 2.892 NM_011527
Tal1
T-cell acute lymphocytic leukemia 1
chr6_-_97129076 2.891 NM_001081111
Tmf1
TATA element modulatory factor 1
chr2_+_112124767 2.882 NM_133648
Slc12a6
solute carrier family 12, member 6
chr2_-_121332347 2.880 NM_026220
Mfap1b
Mfap1a
microfibrillar-associated protein 1B
microfibrillar-associated protein 1A
chr9_+_62189138 2.851 NM_009672
Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr5_+_91332895 2.832 NM_009140
Cxcl2
chemokine (C-X-C motif) ligand 2
chr1_+_187028043 2.815 NM_001163754
Rab3gap2
RAB3 GTPase activating protein subunit 2
chr18_-_6241497 2.810 NM_008448
Kif5b
kinesin family member 5B
chr13_-_47138563 2.780 NM_016785
Tpmt
thiopurine methyltransferase
chr16_+_77013880 2.762 NM_013918
Usp25
ubiquitin specific peptidase 25
chr15_-_86016336 2.757 NM_145475
Cerk
ceramide kinase
chr19_+_59335367 2.640 NM_172523
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr7_+_30553570 2.633 NM_023750
Zfp84
zinc finger protein 84
chr11_+_29273673 2.633 NM_176841
Ccdc88a
coiled coil domain containing 88A
chr2_+_115407409 2.609 NM_001145898
NM_207264
BC052040

cDNA sequence BC052040

chr11_+_106612525 2.579 NM_001033435
Gm885
predicted gene 885
chr8_-_71259021 2.575 NM_172753
Csgalnact1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr5_+_142939884 2.541 NM_172725
C330006K01Rik
RIKEN cDNA C330006K01 gene
chr7_-_30836383 2.514 NM_011748
NM_178733
Zfp14

zinc finger protein 14

chr13_-_21622917 2.510 NM_139141
Zfp192
zinc finger protein 192
chr6_-_93863547 2.495 NM_001083321
NM_001083320
Magi1

membrane associated guanylate kinase, WW and PDZ domain containing 1

chr8_-_37312569 2.489 NM_001081150
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr6_-_148392841 2.461 NM_198967
Tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr13_+_98011057 2.406 NM_007930
Enc1
ectodermal-neural cortex 1
chr19_-_28057437 2.374 NM_001166414
Rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr11_+_51103421 2.353 NM_153393
Col23a1
collagen, type XXIII, alpha 1
chr4_-_133556751 2.340 NM_026144
Dhdds
dehydrodolichyl diphosphate synthase
chr9_+_58430031 2.340 NM_009145
Nptn
neuroplastin
chr7_-_30736911 2.336 NM_178384
Zfp74
zinc finger protein 74
chrX_-_103124651 2.305 NM_009530
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr9_-_99469275 2.303 NM_001166138
NM_028768
Armc8

armadillo repeat containing 8

chr5_-_136020946 2.288 NM_146001
Hip1
huntingtin interacting protein 1
chr19_+_46647844 2.278 NM_053196
Sfxn2
sideroflexin 2
chr15_-_77949709 2.269 NM_007583
Cacng2
calcium channel, voltage-dependent, gamma subunit 2
chr1_-_78193381 2.268 NM_001159520
NM_008781
Pax3

paired box gene 3

chr11_-_62270815 2.267 NM_011308
Ncor1
nuclear receptor co-repressor 1
chr1_-_159342713 2.248 NM_177644
Rasal2
RAS protein activator like 2
chr17_-_46968361 2.238 NM_001100452
BC032203
cDNA sequence BC032203
chr5_+_123794456 2.216 NM_029850
Bcl7a
B-cell CLL/lymphoma 7A
chr13_-_70980619 2.215 NM_172053
Adamts16
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16
chr11_+_105451296 2.206 NM_181071
Tanc2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr17_-_66799086 2.195 NM_001114098
NM_172963
1110012J17Rik

RIKEN cDNA 1110012J17 gene

chr11_+_60879305 2.188 NM_010603
Kcnj12
potassium inwardly-rectifying channel, subfamily J, member 12
chr2_-_165710128 2.179 NM_027230
Zmynd8
zinc finger, MYND-type containing 8
chr11_-_88579517 2.143 NM_054043
Msi2
Musashi homolog 2 (Drosophila)
chr5_+_125921888 2.118 NM_029752
Bri3bp
Bri3 binding protein
chr3_-_101728226 2.117 NM_001039371
Slc22a15
solute carrier family 22 (organic anion/cation transporter), member 15
chr13_+_21454688 2.110 NM_016684
Zscan12
zinc finger and SCAN domain containing 12
chr19_-_34715232 2.082 NM_053217
2010002M12Rik
RIKEN cDNA 2010002M12 gene
chr2_-_39046224 2.071 NM_178778
Scai
suppressor of cancer cell invasion
chr19_-_28085534 2.059 NM_011265
Rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr19_+_17030600 2.010 NM_181348
Prune2
prune homolog 2 (Drosophila)
chr16_-_3872273 2.005 NM_001033159
Zfp597
zinc finger protein 597

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.70 1.33e-03 GO:0050767 regulation of neurogenesis
1.63 1.62e-03 GO:0031323 regulation of cellular metabolic process
3.99 1.77e-03 GO:0045664 regulation of neuron differentiation
3.23 5.46e-03 GO:0060284 regulation of cell development
3.31 6.78e-03 GO:0051960 regulation of nervous system development
1.54 7.24e-03 GO:0019222 regulation of metabolic process
2.16 8.13e-03 GO:0007399 nervous system development
2.42 1.90e-02 GO:0048699 generation of neurons
4.43 2.17e-02 GO:0010975 regulation of neuron projection development
4.43 2.17e-02 GO:0042391 regulation of membrane potential
1.55 2.68e-02 GO:0080090 regulation of primary metabolic process
1.54 4.42e-02 GO:0060255 regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.21 5.42e-03 GO:0044456 synapse part
2.77 5.76e-03 GO:0045202 synapse
1.41 1.09e-02 GO:0005634 nucleus
1.19 4.93e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.43 6.83e-04 GO:0005515 protein binding
1.21 1.19e-02 GO:0005488 binding
2.57 1.71e-02 GO:0019904 protein domain specific binding