Motif ID: ZBTB6.p2

Z-value: 2.394


Transcription factors associated with ZBTB6.p2:

Gene SymbolEntrez IDGene Name
Zbtb6 241322 zinc finger and BTB domain containing 6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb6chr2_-_37286367-0.009.5e-01Click!


Activity profile for motif ZBTB6.p2.

activity profile for motif ZBTB6.p2


Sorted Z-values histogram for motif ZBTB6.p2

Sorted Z-values for motif ZBTB6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_73509668 75.285 Rtn1
reticulon 1
chr12_-_73509537 59.232 Rtn1
reticulon 1
chr15_+_78744328 53.931 NM_020271
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr18_-_25912171 42.968 Celf4
CUGBP, Elav-like family member 4
chr11_+_83223154 41.550 Rasl10b
RAS-like, family 10, member B
chr11_+_83223573 39.635 NM_001013386
Rasl10b
RAS-like, family 10, member B
chr3_+_34548916 35.741 NM_011443
Sox2
SRY-box containing gene 2
chr8_+_96334879 33.166 Gnao1
guanine nucleotide binding protein, alpha O
chr15_+_91881593 32.294 NM_001159648
Cntn1
contactin 1
chr12_-_73509925 30.816 NM_153457
Rtn1
reticulon 1
chr3_+_34549057 28.995 Sox2
SRY-box containing gene 2
chr6_+_110595586 28.955 NM_177328
Grm7
glutamate receptor, metabotropic 7
chr1_-_75260687 28.935 NM_008985
Ptprn
protein tyrosine phosphatase, receptor type, N
chr14_-_13655592 28.039 NM_001042617
NM_012061
Cadps

Ca2+-dependent secretion activator

chr14_-_13655558 27.740 Cadps
Ca2+-dependent secretion activator
chr15_-_98637560 27.186 Ddn
dendrin
chr7_-_31230564 26.384 Aplp1
amyloid beta (A4) precursor-like protein 1
chr18_-_43058544 25.164 NM_027531
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr11_-_69373555 24.825 Efnb3
ephrin B3
chr7_-_31230577 24.817 NM_007467
Aplp1
amyloid beta (A4) precursor-like protein 1
chr18_+_37098858 23.951 NM_198117
Pcdha2
protocadherin alpha 2
chr10_+_34017221 23.713 NM_030203
Tspyl4
TSPY-like 4
chr11_-_69373707 23.551 NM_007911
Efnb3
ephrin B3
chr12_+_16660521 22.884 Ntsr2
neurotensin receptor 2
chr2_+_92439758 22.619 NM_023850
Chst1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr1_-_166387998 22.421 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr17_-_25073798 22.415 Mapk8ip3
mitogen-activated protein kinase 8 interacting protein 3
chr4_+_13670582 21.297 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_+_64845887 20.853 NM_001038701
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr2_+_90729768 20.323 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr13_+_19040215 20.316 NM_175007
Amph
amphiphysin
chr2_-_151458299 19.919 Snph
syntaphilin
chr14_+_56129440 19.876 Cpne6
copine VI
chr8_+_128519295 19.692 Kcnk1
potassium channel, subfamily K, member 1
chr7_+_107756292 19.586 Rab6
RAB6, member RAS oncogene family
chr1_-_134287712 19.260 NM_178874
Tmcc2
transmembrane and coiled-coil domains 2
chr17_-_27650285 19.221 Grm4
glutamate receptor, metabotropic 4
chrX_+_132567905 19.150 NM_029541
6530401D17Rik
RIKEN cDNA 6530401D17 gene
chr7_+_107756205 19.037 Rab6
RAB6, member RAS oncogene family
chr9_+_110148568 18.729 Cspg5
chondroitin sulfate proteoglycan 5
chr10_+_7309565 18.703 NM_172784
Lrp11
low density lipoprotein receptor-related protein 11
chr7_+_31076771 18.700 NM_001081114
Clip3
CAP-GLY domain containing linker protein 3
chr13_+_74146852 18.645 NM_182839
Tppp
tubulin polymerization promoting protein
chr14_+_60997104 18.549 NM_001164705
NM_028113
Fam123a

family with sequence similarity 123, member A

chr18_-_21458623 18.358 NM_001033445
Fam59a
family with sequence similarity 59, member A
chr2_-_151458256 18.084 NM_198214
Snph
syntaphilin
chr8_+_128519001 18.078 NM_008430
Kcnk1
potassium channel, subfamily K, member 1
chr10_+_40603330 18.059 NM_031877
Wasf1
WASP family 1
chr9_-_91259829 17.989 Zic1
zinc finger protein of the cerebellum 1
chr17_-_29374656 17.825 NM_153166
Cpne5
copine V
chr17_-_25073897 17.769 NM_001163447
NM_001163448
NM_001163449
NM_001163450
NM_001163451
NM_001163453
NM_013931
Mapk8ip3






mitogen-activated protein kinase 8 interacting protein 3






chr9_-_44096170 17.539 NM_138955
Abcg4
ATP-binding cassette, sub-family G (WHITE), member 4
chr4_-_68615382 17.471 NM_019967
Dbc1
deleted in bladder cancer 1 (human)
chr12_-_71448600 17.431 NM_001110202
NM_001110203
NM_053167
Trim9


tripartite motif-containing 9


chr15_+_82105322 17.421 NM_011889
Sept3
septin 3
chr7_+_31076852 17.280 Clip3
CAP-GLY domain containing linker protein 3
chr9_-_53822931 17.183 Elmod1
ELMO domain containing 1
chr4_-_136891931 17.009 Cdc42
cell division cycle 42 homolog (S. cerevisiae)
chr14_+_60997156 16.889 Fam123a
family with sequence similarity 123, member A
chr9_+_108728650 16.751 NM_080437
Celsr3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr10_-_67375332 16.724 NM_178679
Zfp365
zinc finger protein 365
chr17_+_37187550 16.325 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_-_53009546 16.204 NM_144953
1700019D03Rik
RIKEN cDNA 1700019D03 gene
chr15_-_75921924 16.045 Nrbp2
nuclear receptor binding protein 2
chr2_+_28061156 16.017 NM_001038612
NM_019498
Olfm1

olfactomedin 1

chrX_+_132528317 15.999 NM_029823
6530401D17Rik
2900062L11Rik
RIKEN cDNA 6530401D17 gene
RIKEN cDNA 2900062L11 gene
chr2_+_38206759 15.728 NM_010710
Lhx2
LIM homeobox protein 2
chr7_+_64846528 15.401 NM_008071
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr2_-_53937785 15.368 NM_023396
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chrX_+_78315963 15.309 NM_138751
Tmem47
transmembrane protein 47
chr1_+_75542840 15.048 NM_009208
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chrX_+_78316003 14.982 Tmem47
transmembrane protein 47
chr9_+_45178485 14.961 Fxyd6
FXYD domain-containing ion transport regulator 6
chr9_-_60535699 14.958 Lrrc49
leucine rich repeat containing 49
chrX_+_5624820 14.920 Nudt11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr5_+_34339351 14.913 Nat8l
N-acetyltransferase 8-like
chr18_-_74224541 14.895 NM_172632
Mapk4
mitogen-activated protein kinase 4
chr9_+_45178521 14.853 Fxyd6
FXYD domain-containing ion transport regulator 6
chr4_+_138011061 14.844 NM_025451
Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr5_+_137729501 14.725 NM_009599
Ache
acetylcholinesterase
chr6_+_85978802 14.657 Add2
adducin 2 (beta)
chr5_+_34064372 14.626 NM_008010
NM_001163215
Fgfr3

fibroblast growth factor receptor 3

chr17_-_66799086 14.537 NM_001114098
NM_172963
1110012J17Rik

RIKEN cDNA 1110012J17 gene

chrX_-_71070284 14.512 NM_001029868
Pdzd4
PDZ domain containing 4
chr11_-_118770873 14.483 NM_001024931
NM_001039167
NM_001039168
Rbfox3


RNA binding protein, fox-1 homolog (C. elegans) 3


chr6_+_8899165 14.458 Nxph1
neurexophilin 1
chr11_-_5965743 14.439 NM_001174053
NM_001174054
NM_007595
Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr9_+_103014279 14.435 Rab6b
RAB6B, member RAS oncogene family
chr15_-_37721754 14.428 NM_001170866
Ncald
neurocalcin delta
chr11_-_118770859 14.403 Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr15_+_103333440 14.324 Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr6_-_127718746 14.321 NM_201371
Prmt8
protein arginine N-methyltransferase 8
chr7_+_64846558 14.092 Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr9_-_56008595 14.082 Tspan3
tetraspanin 3
chr4_+_129662284 14.049 NM_173071
Bai2
brain-specific angiogenesis inhibitor 2
chr9_-_56008819 13.956 Tspan3
tetraspanin 3
chr18_+_64425037 13.929 St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr8_+_98226914 13.883 NM_001195006
NM_145602
Ndrg4

N-myc downstream regulated gene 4

chr4_+_104040160 13.879 NM_010014
NM_177259
Dab1

disabled homolog 1 (Drosophila)

chr1_-_134638361 13.853 NM_001160317
NM_182716
Nfasc

neurofascin

chr11_-_5965544 13.844 Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chr7_-_116925058 13.834 NM_020610
Nrip3
nuclear receptor interacting protein 3
chr4_+_137220675 13.829 Rap1gap
Rap1 GTPase-activating protein
chr9_+_57351848 13.813 NM_133982
Rpp25
ribonuclease P 25 subunit (human)
chr5_+_34338625 13.787 NM_001001985
Nat8l
N-acetyltransferase 8-like
chr9_-_56008770 13.766 Tspan3
tetraspanin 3
chr12_-_73337707 13.664 NM_001007596
Rtn1
reticulon 1
chr5_-_84846256 13.637 Epha5
Eph receptor A5
chr10_-_67375130 13.601 Zfp365
zinc finger protein 365
chr6_+_85978713 13.550 Add2
adducin 2 (beta)
chr9_+_103014463 13.461 Rab6b
RAB6B, member RAS oncogene family
chr11_-_64976408 13.409 NM_001099288
NM_175003
Arhgap44

Rho GTPase activating protein 44

chr13_+_54472806 13.372 Cplx2
complexin 2
chr15_-_99358387 13.348 NM_001038658
NM_028224
Faim2

Fas apoptotic inhibitory molecule 2

chr15_-_79635069 13.330 Nptxr
neuronal pentraxin receptor
chr15_+_99501148 13.249 NM_009597
Accn2
amiloride-sensitive cation channel 2, neuronal
chr2_+_132607432 13.229 Chgb
chromogranin B
chr6_-_13788453 13.198 Gpr85
G protein-coupled receptor 85
chr4_-_133053867 13.174 Trnp1
TMF1-regulated nuclear protein 1
chr15_-_98638348 13.022 NM_001013741
Ddn
dendrin
chr6_-_13788580 12.997 Gpr85
G protein-coupled receptor 85
chr4_-_124539414 12.983 NM_001007573
Maneal
mannosidase, endo-alpha-like
chr4_+_129662110 12.944 Bai2
brain-specific angiogenesis inhibitor 2
chr15_-_98638230 12.921 Ddn
dendrin
chr8_-_126383327 12.760 1700054N08Rik
RIKEN cDNA 1700054N08 gene
chr3_+_14886253 12.746 NM_009801
Car2
carbonic anhydrase 2
chr9_-_53823107 12.639 NM_177769
Elmod1
ELMO domain containing 1
chr12_-_71448300 12.620 Trim9
tripartite motif-containing 9
chr4_+_8462766 12.601 NM_021518
Rab2a
RAB2A, member RAS oncogene family
chr2_-_92232506 12.599 Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
chr12_+_117724182 12.526 NM_011215
Ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr15_+_97938874 12.483 NM_001163487
Pfkm
phosphofructokinase, muscle
chr17_-_57199207 12.386 NM_025877
Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr14_+_14286471 12.234 NM_001163032
Synpr
synaptoporin
chr7_+_25266986 12.217 NM_153112
Cadm4
cell adhesion molecule 4
chr6_-_124813970 12.178 Gpr162
G protein-coupled receptor 162
chr2_+_132607408 12.149 Chgb
chromogranin B
chr6_+_29867012 12.135 NM_001037740
NM_177204
Fam40b

family with sequence similarity 40, member B

chr2_+_132607398 12.104 Chgb
chromogranin B
chr5_+_73882264 12.056 NM_001190733
NM_178896
Dcun1d4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr10_+_13685882 12.019 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr2_-_113669159 11.935 Scg5
secretogranin V
chr6_-_124813720 11.848 Gpr162
G protein-coupled receptor 162
chr2_-_152202301 11.826 NM_001009948
Nrsn2
neurensin 2
chr7_+_3303657 11.813 NM_011102
Prkcc
protein kinase C, gamma
chr10_-_33343965 11.668 Clvs2
clavesin 2
chr10_+_90038471 11.610 NM_001177397
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_-_133054355 11.550 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr1_+_174271338 11.541 NM_001039484
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr11_+_29593657 11.512 NM_194051
Rtn4
reticulon 4
chr4_-_57002965 11.483 6430704M03Rik
RIKEN cDNA 6430704M03 gene
chr3_+_14886681 11.449 Car2
carbonic anhydrase 2
chr11_-_53293696 11.441 NM_183173
Ankrd43
ankyrin repeat domain 43
chr9_-_56008828 11.438 NM_019793
Tspan3
tetraspanin 3
chr11_-_53293580 11.427 Ankrd43
ankyrin repeat domain 43
chr3_-_107320881 11.406 NM_172271
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr2_-_113669243 11.401 NM_009162
Scg5
secretogranin V
chr8_-_67373608 11.389 Klhl2
kelch-like 2, Mayven (Drosophila)
chr13_-_36826245 11.384 NM_153529
Nrn1
neuritin 1
chr15_-_79635156 11.292 Nptxr
neuronal pentraxin receptor
chr8_+_121970660 11.286 Necab2
N-terminal EF-hand calcium binding protein 2
chr5_+_34339258 11.285 Nat8l
N-acetyltransferase 8-like
chr13_+_48356795 11.283 NM_031166
Id4
inhibitor of DNA binding 4
chr11_+_71564204 11.281 NM_177618
Wscd1
WSC domain containing 1
chr18_+_38115192 11.277 NM_153793
Rell2
RELT-like 2
chr11_-_5965555 11.275 Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chr4_+_8462756 11.234 Rab2a
RAB2A, member RAS oncogene family
chr6_-_126595818 11.211 NM_010595
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr15_+_103333554 11.180 NM_008800
Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr2_-_180869947 11.098 Kcnq2
potassium voltage-gated channel, subfamily Q, member 2
chr2_-_118529608 11.040 NM_001081971
Gm1337
predicted gene 1337
chr9_+_103014374 11.023 NM_173781
Rab6b
RAB6B, member RAS oncogene family
chr2_-_127308234 11.009 NM_001111331
Kcnip3
Kv channel interacting protein 3, calsenilin
chr4_-_151235861 10.945 NM_001081557
NM_001195565
Camta1

calmodulin binding transcription activator 1

chr13_-_111070344 10.942 Rab3c
RAB3C, member RAS oncogene family
chr5_+_37633353 10.842 Crmp1
collapsin response mediator protein 1
chr4_-_149148173 10.838 NM_027460
Slc25a33
solute carrier family 25, member 33
chr14_+_71289902 10.825 Gfra2
glial cell line derived neurotrophic factor family receptor alpha 2
chr7_+_3303770 10.819 Prkcc
protein kinase C, gamma
chr17_+_86567003 10.754 NM_011104
Prkce
protein kinase C, epsilon
chr19_+_6427922 10.724 NM_020253
Nrxn2
neurexin II
chr4_+_126846429 10.696 NM_198618
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr15_-_37722161 10.599 NM_134094
Ncald
neurocalcin delta
chr6_+_49772688 10.528 NM_023456
Npy
neuropeptide Y
chr9_-_69989285 10.500 NM_029784
Fam81a
family with sequence similarity 81, member A
chr10_-_80945445 10.438 NM_176954
Celf5
CUGBP, Elav-like family member 5
chr16_-_32246968 10.434 NM_173439
Fbxo45
F-box protein 45
chr11_+_55017825 10.426 NM_153139
Slc36a1
solute carrier family 36 (proton/amino acid symporter), member 1
chr12_-_73337534 10.422 Rtn1
reticulon 1
chr8_+_107872157 10.413 NM_001081332
Slc9a5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr5_+_88994386 10.372 Rufy3
RUN and FYVE domain containing 3
chr1_+_75479559 10.372 Tmem198
transmembrane protein 198
chr7_+_125856066 10.346 NM_182995
6330503K22Rik
RIKEN cDNA 6330503K22 gene
chr2_-_91284827 10.344 1110051M20Rik
RIKEN cDNA 1110051M20 gene
chr11_-_115128586 10.257 Grin2c
glutamate receptor, ionotropic, NMDA2C (epsilon 3)
chr10_+_78243274 10.256 Slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr2_+_135883662 10.254 NM_029530
6330527O06Rik
RIKEN cDNA 6330527O06 gene
chr3_-_117063317 10.226 D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr11_-_35612058 10.183 Fbll1
fibrillarin-like 1
chr14_+_56129284 10.162 NM_001136057
NM_001146183
Cpne6

copine VI


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.83 7.00e-12 GO:0007399 nervous system development
1.49 1.01e-10 GO:0006810 transport
1.43 2.54e-10 GO:0051179 localization
1.47 3.24e-10 GO:0051234 establishment of localization
1.83 9.98e-08 GO:0022008 neurogenesis
1.86 1.27e-07 GO:0048699 generation of neurons
1.71 5.46e-07 GO:0006796 phosphate metabolic process
1.71 6.32e-07 GO:0006793 phosphorus metabolic process
1.55 4.09e-06 GO:0023051 regulation of signaling
2.22 6.39e-06 GO:0050767 regulation of neurogenesis
2.09 9.16e-06 GO:0060284 regulation of cell development
2.33 1.37e-05 GO:0045664 regulation of neuron differentiation
2.70 2.11e-05 GO:0010975 regulation of neuron projection development
2.16 2.36e-05 GO:0019226 transmission of nerve impulse
2.16 2.36e-05 GO:0035637 multicellular organismal signaling
1.70 4.23e-05 GO:0016310 phosphorylation
2.50 6.57e-05 GO:0031344 regulation of cell projection organization
1.68 6.94e-05 GO:0051128 regulation of cellular component organization
1.46 7.30e-05 GO:0006464 protein modification process
2.28 7.35e-05 GO:0007268 synaptic transmission
2.05 8.25e-05 GO:0051960 regulation of nervous system development
3.23 2.53e-04 GO:0006836 neurotransmitter transport
1.43 2.79e-04 GO:0043412 macromolecule modification
2.07 3.49e-04 GO:0009894 regulation of catabolic process
1.32 4.05e-04 GO:0016043 cellular component organization
1.93 7.30e-04 GO:0044057 regulation of system process
1.83 7.64e-04 GO:0030030 cell projection organization
2.03 9.18e-04 GO:0031175 neuron projection development
2.25 1.01e-03 GO:0031644 regulation of neurological system process
1.36 1.34e-03 GO:0071842 cellular component organization at cellular level
1.98 1.66e-03 GO:0051130 positive regulation of cellular component organization
2.66 2.24e-03 GO:0033124 regulation of GTP catabolic process
1.28 2.83e-03 GO:0071840 cellular component organization or biogenesis
3.21 3.03e-03 GO:0048167 regulation of synaptic plasticity
4.10 3.43e-03 GO:0048168 regulation of neuronal synaptic plasticity
1.51 3.79e-03 GO:0035556 intracellular signal transduction
1.33 4.85e-03 GO:0044267 cellular protein metabolic process
1.73 4.94e-03 GO:0030182 neuron differentiation
2.16 5.30e-03 GO:0051129 negative regulation of cellular component organization
1.65 5.61e-03 GO:0007154 cell communication
2.59 6.11e-03 GO:0043087 regulation of GTPase activity
10.08 6.60e-03 GO:0048172 regulation of short-term neuronal synaptic plasticity
1.83 6.74e-03 GO:0007267 cell-cell signaling
2.10 6.83e-03 GO:0051056 regulation of small GTPase mediated signal transduction
2.03 8.35e-03 GO:0031329 regulation of cellular catabolic process
1.61 1.03e-02 GO:0006468 protein phosphorylation
2.15 1.04e-02 GO:0046578 regulation of Ras protein signal transduction
2.43 1.08e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.43 1.08e-02 GO:0022604 regulation of cell morphogenesis
2.43 1.08e-02 GO:0030811 regulation of nucleotide catabolic process
2.43 1.08e-02 GO:0033121 regulation of purine nucleotide catabolic process
11.76 1.20e-02 GO:0021681 cerebellar granular layer development
11.76 1.20e-02 GO:0021683 cerebellar granular layer morphogenesis
2.00 1.26e-02 GO:0006140 regulation of nucleotide metabolic process
2.16 1.29e-02 GO:0051969 regulation of transmission of nerve impulse
1.45 1.38e-02 GO:0009966 regulation of signal transduction
2.21 1.38e-02 GO:0050804 regulation of synaptic transmission
1.16 1.39e-02 GO:0044237 cellular metabolic process
1.31 1.45e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.83 1.72e-02 GO:0007610 behavior
1.96 2.59e-02 GO:0007264 small GTPase mediated signal transduction
1.23 2.60e-02 GO:0031323 regulation of cellular metabolic process
3.74 2.65e-02 GO:0007269 neurotransmitter secretion
1.47 2.99e-02 GO:0051641 cellular localization
1.21 3.17e-02 GO:0019222 regulation of metabolic process
1.25 3.37e-02 GO:0007275 multicellular organismal development
4.46 3.61e-02 GO:0048169 regulation of long-term neuronal synaptic plasticity
1.38 3.62e-02 GO:0051239 regulation of multicellular organismal process
1.75 4.07e-02 GO:0048666 neuron development
1.28 4.28e-02 GO:0048731 system development
1.61 4.86e-02 GO:0016192 vesicle-mediated transport
3.39 4.87e-02 GO:0014013 regulation of gliogenesis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.20 3.58e-16 GO:0005622 intracellular
2.37 1.15e-15 GO:0043005 neuron projection
1.19 3.57e-15 GO:0044424 intracellular part
1.88 1.62e-13 GO:0042995 cell projection
1.23 1.53e-12 GO:0005737 cytoplasm
2.32 3.03e-12 GO:0045202 synapse
1.10 6.50e-11 GO:0005623 cell
1.10 6.50e-11 GO:0044464 cell part
2.47 2.62e-10 GO:0044297 cell body
1.72 4.33e-10 GO:0000267 cell fraction
2.48 6.22e-10 GO:0043025 neuronal cell body
1.18 2.38e-09 GO:0043229 intracellular organelle
1.18 2.51e-09 GO:0043226 organelle
1.82 2.67e-09 GO:0005624 membrane fraction
2.52 4.85e-09 GO:0030425 dendrite
2.37 9.00e-09 GO:0044456 synapse part
1.77 1.65e-08 GO:0005626 insoluble fraction
1.32 1.35e-07 GO:0071944 cell periphery
1.32 3.16e-07 GO:0005886 plasma membrane
1.17 5.44e-07 GO:0043227 membrane-bounded organelle
1.17 1.21e-06 GO:0043231 intracellular membrane-bounded organelle
2.35 1.93e-06 GO:0030424 axon
2.04 2.33e-06 GO:0044463 cell projection part
2.94 2.86e-06 GO:0019717 synaptosome
1.81 4.18e-06 GO:0030054 cell junction
2.94 4.74e-06 GO:0033267 axon part
1.21 4.54e-05 GO:0044444 cytoplasmic part
1.39 2.16e-04 GO:0044459 plasma membrane part
1.44 2.73e-04 GO:0005856 cytoskeleton
2.01 4.59e-04 GO:0048471 perinuclear region of cytoplasm
1.52 1.23e-03 GO:0005794 Golgi apparatus
1.52 1.50e-03 GO:0044430 cytoskeletal part
2.73 2.88e-03 GO:0008021 synaptic vesicle
1.21 4.82e-03 GO:0044446 intracellular organelle part
2.26 5.30e-03 GO:0045211 postsynaptic membrane
1.20 6.20e-03 GO:0044422 organelle part
1.41 7.97e-03 GO:0031090 organelle membrane
1.17 1.08e-02 GO:0005634 nucleus
2.26 1.47e-02 GO:0030136 clathrin-coated vesicle
3.71 1.87e-02 GO:0043198 dendritic shaft
1.83 2.21e-02 GO:0044431 Golgi apparatus part
1.11 2.21e-02 GO:0016020 membrane
2.66 2.61e-02 GO:0044306 neuron projection terminus
2.71 3.05e-02 GO:0043679 axon terminus
3.53 3.29e-02 GO:0042734 presynaptic membrane
4.95 3.53e-02 GO:0008328 ionotropic glutamate receptor complex
1.46 4.32e-02 GO:0012505 endomembrane system
1.55 4.39e-02 GO:0015630 microtubule cytoskeleton
1.47 4.81e-02 GO:0031982 vesicle

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.35 8.35e-16 GO:0005515 protein binding
1.17 2.25e-11 GO:0005488 binding
1.70 1.05e-05 GO:0016301 kinase activity
1.75 1.78e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.61 3.80e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.42 5.83e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.37 8.81e-05 GO:0000166 nucleotide binding
1.41 9.50e-05 GO:0017076 purine nucleotide binding
1.41 1.08e-04 GO:0032555 purine ribonucleotide binding
1.41 1.13e-04 GO:0032553 ribonucleotide binding
1.60 2.54e-04 GO:0019899 enzyme binding
1.71 8.76e-04 GO:0004672 protein kinase activity
1.42 1.31e-03 GO:0005524 ATP binding
1.41 1.43e-03 GO:0030554 adenyl nucleotide binding
1.41 1.63e-03 GO:0032559 adenyl ribonucleotide binding
1.82 1.98e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.55 2.12e-03 GO:0030234 enzyme regulator activity
2.05 2.36e-03 GO:0005083 small GTPase regulator activity
1.36 3.46e-03 GO:0016740 transferase activity
4.41 4.17e-03 GO:0035254 glutamate receptor binding
1.78 4.73e-03 GO:0004674 protein serine/threonine kinase activity
1.78 6.24e-03 GO:0030695 GTPase regulator activity
1.62 2.44e-02 GO:0008092 cytoskeletal protein binding
1.64 2.53e-02 GO:0008324 cation transmembrane transporter activity
1.45 3.75e-02 GO:0022892 substrate-specific transporter activity