Motif ID: ZNF143.p2

Z-value: 3.828


Transcription factors associated with ZNF143.p2:

Gene SymbolEntrez IDGene Name
Zfp143 20841 zinc finger protein 143

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp143chr7_+_1172051940.334.9e-06Click!


Activity profile for motif ZNF143.p2.

activity profile for motif ZNF143.p2


Sorted Z-values histogram for motif ZNF143.p2

Sorted Z-values for motif ZNF143.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF143.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_117710532 70.316 NM_001012273
NM_009689
Birc5

baculoviral IAP repeat-containing 5

chr5_+_34000745 67.111 NM_001040435
Tacc3
transforming, acidic coiled-coil containing protein 3
chr7_+_13864164 62.785 NM_010715
Lig1
ligase I, DNA, ATP-dependent
chr18_+_34784277 44.408 NM_001166407
Kif20a
kinesin family member 20A
chr10_-_128002934 44.133 Pa2g4
proliferation-associated 2G4
chr18_+_34784589 42.417 NM_009004
NM_001166406
Kif20a

kinesin family member 20A

chr10_-_128003058 36.249 Pa2g4
proliferation-associated 2G4
chr10_-_128002991 35.480 Pa2g4
proliferation-associated 2G4
chr10_-_128002987 35.143 NM_011119
Pa2g4
proliferation-associated 2G4
chr15_-_81560283 33.053 Rangap1
RAN GTPase activating protein 1
chr4_+_107040647 31.104 Tmem48
transmembrane protein 48
chr15_-_81560257 31.021 Rangap1
RAN GTPase activating protein 1
chr15_-_81560302 30.436 Rangap1
RAN GTPase activating protein 1
chr15_-_81560309 30.344 NM_001146174
NM_011241
Rangap1

RAN GTPase activating protein 1

chr8_+_73988823 28.436 NM_053162
Mrpl34
mitochondrial ribosomal protein L34
chr12_-_114067537 28.372 NM_028023
Cdca4
cell division cycle associated 4
chr4_+_107040388 27.219 NM_028355
Tmem48
transmembrane protein 48
chr4_-_86257921 27.105 NM_173400
Haus6
HAUS augmin-like complex, subunit 6
chr9_-_34983552 26.249 NM_027030
Dcps
decapping enzyme, scavenger
chr4_+_107040634 26.042 Tmem48
transmembrane protein 48
chr17_-_23810736 22.750 NM_001008425
Thoc6
THO complex 6 homolog (Drosophila)
chr2_+_118938549 21.183 NM_011234
Rad51
RAD51 homolog (S. cerevisiae)
chr10_-_126748678 21.049 Mars
methionine-tRNA synthetase
chr17_-_23810808 20.492 Thoc6
THO complex 6 homolog (Drosophila)
chr7_+_129302998 20.455 Plk1
polo-like kinase 1 (Drosophila)
chr15_+_102348622 20.349 NM_009319
Tarbp2
TAR (HIV) RNA binding protein 2
chr2_+_119444033 20.143 NM_001042652
NM_133851
Nusap1

nucleolar and spindle associated protein 1

chr10_-_80958977 19.946 NM_134009
Ncln
nicalin homolog (zebrafish)
chr7_+_17323737 19.896 NM_198613
Ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr7_+_129303029 19.762 Plk1
polo-like kinase 1 (Drosophila)
chr1_-_20810238 19.519 NM_008563
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr7_+_129302950 19.490 NM_011121
Plk1
polo-like kinase 1 (Drosophila)
chr8_+_108384479 19.206 NM_026532
Nutf2
nuclear transport factor 2
chr10_+_127452219 18.614 Prim1
DNA primase, p49 subunit
chr19_-_10278231 18.417 NM_007999
Fen1
flap structure specific endonuclease 1
chr7_+_123236814 17.757 NM_019772
1110004F10Rik
RIKEN cDNA 1110004F10 gene
chr3_-_88905775 17.476 NM_134469
Fdps
farnesyl diphosphate synthetase
chr10_+_127452270 17.468 NM_008921
Prim1
DNA primase, p49 subunit
chr19_+_37450854 17.397 NM_010615
Kif11
kinesin family member 11
chr10_-_80380806 17.331 NM_010722
Lmnb2
lamin B2
chr11_+_98769162 17.296 NM_001025779
Cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr11_+_98769122 17.150 Cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr19_+_5601857 17.067 NM_026616
Rnaseh2c
ribonuclease H2, subunit C
chr3_-_96001504 16.756 NM_026975
Bola1
bolA-like 1 (E. coli)
chr2_+_164595389 16.732 Ube2c
ubiquitin-conjugating enzyme E2C
chr2_+_118423946 16.718 NM_009773
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr5_+_144165615 16.550 Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr9_+_107489981 16.504 NM_025903
Ifrd2
interferon-related developmental regulator 2
chr14_-_55136145 16.358 NM_013768
Prmt5
protein arginine N-methyltransferase 5
chr2_+_118424004 16.353 Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr15_-_75760134 16.018 NM_031201
Tsta3
tissue specific transplantation antigen P35B
chr2_-_84567398 15.906 Clp1
CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)
chr2_-_84567424 15.766 NM_133840
Clp1
CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)
chr8_+_108734906 15.739 NM_145404
Prmt7
protein arginine N-methyltransferase 7
chr2_+_164595447 15.569 Ube2c
ubiquitin-conjugating enzyme E2C
chr12_+_107248496 15.510 Vrk1
vaccinia related kinase 1
chr2_+_164595415 15.419 NM_026785
Ube2c
ubiquitin-conjugating enzyme E2C
chr15_+_102126735 15.313 Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr19_+_34996847 15.274 NM_183046
Kif20b
kinesin family member 20B
chr15_+_102126686 15.273 NM_001014976
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr9_+_107490100 15.222 Ifrd2
interferon-related developmental regulator 2
chr11_+_95528269 15.068 NM_008831
Phb
prohibitin
chr17_+_56442759 14.878 NM_001111079
NM_010931
Uhrf1

ubiquitin-like, containing PHD and RING finger domains, 1

chr4_-_124614072 14.812 NM_026560
Cdca8
cell division cycle associated 8
chr5_+_140895245 14.633 NM_133916
Eif3b
eukaryotic translation initiation factor 3, subunit B
chr5_-_34000478 14.400 NM_026698
Tmem129
transmembrane protein 129
chrX_+_7305654 14.273 NM_138602
Praf2
PRA1 domain family 2
chr18_-_24178797 13.868 Zfp191
zinc finger protein 191
chr17_-_85190113 13.812 NM_028233
Lrpprc
leucine-rich PPR-motif containing
chr3_+_68808879 13.610 NM_133786
Smc4
structural maintenance of chromosomes 4
chr4_-_116380924 13.602 NM_025962
Mmachc
methylmalonic aciduria cblC type, with homocystinuria
chr2_-_154900132 13.391 Ahcy
S-adenosylhomocysteine hydrolase
chr17_-_35810624 13.292 NM_010364
Gtf2h4
general transcription factor II H, polypeptide 4
chr16_-_18289209 13.290 NM_033324
Dgcr8
DiGeorge syndrome critical region gene 8
chr5_+_124199713 13.181 NM_001042421
Kntc1
kinetochore associated 1
chr6_-_34126949 13.180 NM_021435
Slc35b4
solute carrier family 35, member B4
chr13_-_58316923 13.180 Ubqln1
ubiquilin 1
chr10_+_74980744 13.057 NM_026095
Snrpd3
small nuclear ribonucleoprotein D3
chr10_+_92916150 13.056 Lta4h
leukotriene A4 hydrolase
chr2_-_154900188 13.040 NM_016661
Ahcy
S-adenosylhomocysteine hydrolase
chr2_+_90519527 13.037 Nup160
nucleoporin 160
chr1_-_44159187 13.019 NM_029368
1700029F09Rik
RIKEN cDNA 1700029F09 gene
chr10_-_126748757 12.925 NM_001003913
NM_001171582
Mars

methionine-tRNA synthetase

chr12_-_80292805 12.888 NM_021557
Rdh11
retinol dehydrogenase 11
chr6_+_85381958 12.828 NM_144918
Smyd5
SET and MYND domain containing 5
chr17_-_85189859 12.811 Lrpprc
leucine-rich PPR-motif containing
chr2_-_154900160 12.756 Ahcy
S-adenosylhomocysteine hydrolase
chr3_-_54539285 12.668 NM_001163570
NM_027148
Exosc8

exosome component 8

chr2_+_172847371 12.615 NM_019547
Rbm38
RNA binding motif protein 38
chr8_-_12672048 12.585 NM_198031
Tubgcp3
tubulin, gamma complex associated protein 3
chr6_-_92133945 12.463 NM_025578
Mrps25
mitochondrial ribosomal protein S25
chr5_-_23929349 12.425 Cdk5
cyclin-dependent kinase 5
chr10_+_74980789 12.410 Snrpd3
small nuclear ribonucleoprotein D3
chrX_-_7182450 12.408 NM_138603
Ccdc22
coiled-coil domain containing 22
chr7_-_30954705 12.117 NM_011980
Zfp146
zinc finger protein 146
chr7_-_52241669 12.005 NM_019830
Prmt1
protein arginine N-methyltransferase 1
chr9_-_103104394 11.960 NM_009275
Srprb
signal recognition particle receptor, B subunit
chr4_-_49533914 11.947 NM_178603
Mrpl50
mitochondrial ribosomal protein L50
chr3_+_79433000 11.896 NM_029482
4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr1_+_193645351 11.833 NM_010892
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr19_+_6334978 11.811 NM_001168488
NM_001168489
NM_001168490
NM_008583
Men1



multiple endocrine neoplasia 1



chr11_-_60692533 11.732 NM_001168507
NM_173453
Tmem11

transmembrane protein 11

chr4_-_129318200 11.712 Txlna
taxilin alpha
chr8_-_108734817 11.667 NM_001007567
Slc7a6os
solute carrier family 7, member 6 opposite strand
chr9_+_26807281 11.665 Thyn1
thymocyte nuclear protein 1
chr18_-_78006524 11.571 Haus1
HAUS augmin-like complex, subunit 1
chr2_+_128926721 11.470 NM_009086
Polr1b
polymerase (RNA) I polypeptide B
chr19_+_46130978 11.409 NM_001081214
Pprc1
peroxisome proliferative activated receptor, gamma, coactivator-related 1
chr2_-_153067043 11.409 NM_018807
Plagl2
pleiomorphic adenoma gene-like 2
chr4_-_126738303 11.364 NM_026670
Zmym1
zinc finger, MYM domain containing 1
chr5_-_34000546 11.335 Tmem129
transmembrane protein 129
chrX_-_136533089 11.275 NM_001172147
NM_001172148
NM_153586
Rbm41


RNA binding motif protein 41


chr4_-_138908210 11.184 NM_023536
Mrto4
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr1_+_136859153 11.142 NM_026024
Ube2t
ubiquitin-conjugating enzyme E2T (putative)
chr8_-_108375786 11.114 NM_177150
Cenpt
centromere protein T
chr2_+_70499545 11.106 NM_027352
Gorasp2
golgi reassembly stacking protein 2
chr15_+_85690136 11.027 NM_001168672
Gtse1
G two S phase expressed protein 1
chr4_+_134066913 11.024 NM_001081099
2610002D18Rik
RIKEN cDNA 2610002D18 gene
chr1_+_136859183 10.967 Ube2t
ubiquitin-conjugating enzyme E2T (putative)
chr15_+_85690375 10.940 NM_013882
Gtse1
G two S phase expressed protein 1
chr9_+_26807258 10.933 NM_144543
Thyn1
thymocyte nuclear protein 1
chr10_-_80363422 10.903 Timm13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr2_+_153171730 10.845 NM_001039939
Asxl1
additional sex combs like 1 (Drosophila)
chr16_-_87496048 10.838 NM_009840
Cct8
chaperonin containing Tcp1, subunit 8 (theta)
chr14_-_62058627 10.776 NM_008466
Kpna3
karyopherin (importin) alpha 3
chr16_-_16359122 10.603 NM_001025947
NM_152816
Dnm1l

dynamin 1-like

chr8_-_59966523 10.567 NM_021788
Sap30
sin3 associated polypeptide
chr6_-_112646587 10.452 NM_001167730
NM_021385
Rad18

RAD18 homolog (S. cerevisiae)

chr11_+_69393851 10.451 NM_001127233
NM_011640
Trp53

transformation related protein 53

chr15_-_77801154 10.415 NM_018749
Eif3d
eukaryotic translation initiation factor 3, subunit D
chr9_+_48863746 10.332 Zw10
ZW10 homolog (Drosophila), centromere/kinetochore protein
chr11_-_4604308 10.320 NM_197979
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr6_+_35127603 10.234 NM_027513
Nup205
nucleoporin 205
chr4_-_120597563 10.204 NM_001160043
NM_028457
Dem1

defects in morphology 1 homolog (S. cerevisiae)

chr13_-_35998160 10.121 NM_145938
Rpp40
ribonuclease P 40 subunit (human)
chr2_+_130100145 10.031 NM_024193
Nop56
NOP56 ribonucleoprotein homolog (yeast)
chr15_-_9070066 10.025 NM_013787
NM_145468
Skp2

S-phase kinase-associated protein 2 (p45)

chr4_-_129317895 10.009 Txlna
taxilin alpha
chr10_-_80363493 9.987 Timm13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr8_+_96738490 9.866 NM_172410
Nup93
nucleoporin 93
chr1_+_173433608 9.863 NM_019484
Refbp2
RNA and export factor binding protein 2
chr7_-_38892432 9.833 NM_007633
Ccne1
cyclin E1
chr6_-_83004374 9.811 NM_019752
Htra2
HtrA serine peptidase 2
chr11_+_62416376 9.788 2410006H16Rik
RIKEN cDNA 2410006H16 gene
chr11_+_70833337 9.780 Mis12
MIS12 homolog (yeast)
chr8_+_96738448 9.774 Nup93
nucleoporin 93
chr15_+_90054711 9.721 NM_001033441
Alg10b
asparagine-linked glycosylation 10 homolog B (yeast, alpha-1,2-glucosyltransferase)
chr9_+_20833816 9.711 NM_023892
Icam4
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr11_-_60692261 9.702 Tmem11
transmembrane protein 11
chr11_+_51781124 9.688 NM_029976
Cdkn2aipnl
CDKN2A interacting protein N-terminal like
chr7_+_73205221 9.683 NM_021336
Snrpa1
small nuclear ribonucleoprotein polypeptide A'
chr16_-_17111300 9.651 NM_144954
Ppil2
peptidylprolyl isomerase (cyclophilin)-like 2
chr10_-_80363606 9.549 NM_013895
Timm13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr2_-_69044179 9.542 NM_025565
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr9_-_57400530 9.497 NM_025837
Mpi
mannose phosphate isomerase
chr12_-_66273564 9.397 NM_172578
Mis18bp1
MIS18 binding protein 1
chr13_-_58316960 9.394 NM_026842
NM_152234
Ubqln1

ubiquilin 1

chr18_-_78006491 9.362 NM_146089
Haus1
HAUS augmin-like complex, subunit 1
chr11_-_106860803 9.313 NM_010655
Kpna2
karyopherin (importin) alpha 2
chr19_-_9973901 9.274 NM_016692
Incenp
inner centromere protein
chr11_-_101413104 9.259 NM_009764
Brca1
breast cancer 1
chr16_+_18498805 9.218 NM_001081682
Gnb1l
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr12_-_80292830 9.195 Rdh11
retinol dehydrogenase 11
chr10_-_122633922 9.165 NM_027604
Usp15
ubiquitin specific peptidase 15
chr8_+_113443764 9.113 NM_009179
St3gal2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr16_+_44724394 9.105 NM_145972
BC027231
cDNA sequence BC027231
chr5_+_23900197 9.083 Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr7_+_73205454 9.072 Snrpa1
small nuclear ribonucleoprotein polypeptide A'
chr11_-_115873976 8.934 NM_016905
Galk1
galactokinase 1
chr11_-_107050573 8.932 NM_001161329
NM_133702
Nol11

nucleolar protein 11

chr4_+_62069801 8.856 NM_027297
Prpf4
PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr1_-_179726514 8.794 NM_007422
Adss
adenylosuccinate synthetase, non muscle
chr2_+_166888719 8.745 1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr5_-_24083072 8.678 Abcf2
ATP-binding cassette, sub-family F (GCN20), member 2
chr11_-_106860750 8.667 Kpna2
karyopherin (importin) alpha 2
chr4_-_132399023 8.639 NM_146154
Ppp1r8
protein phosphatase 1, regulatory (inhibitor) subunit 8
chr18_-_85120825 8.637 1700034H14Rik
RIKEN cDNA 1700034H14 gene
chr7_+_73205419 8.634 Snrpa1
small nuclear ribonucleoprotein polypeptide A'
chr12_-_114067236 8.567 Cdca4
cell division cycle associated 4
chr8_-_110112368 8.561 NM_010817
Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr2_+_152673699 8.502 NM_001141975
NM_001141976
NM_001141977
NM_001141978
NM_028109
Tpx2




TPX2, microtubule-associated protein homolog (Xenopus laevis)




chr12_+_85291557 8.490 NM_023633
2410016O06Rik
RIKEN cDNA 2410016O06 gene
chr17_+_26389911 8.490 Luc7l
Luc7 homolog (S. cerevisiae)-like
chr11_-_70783381 8.425 Nup88
nucleoporin 88
chr2_+_119444452 8.425 Nusap1
nucleolar and spindle associated protein 1
chr11_-_70783455 8.419 NM_001083331
NM_172394
Nup88

nucleoporin 88

chr7_+_51723446 8.405 Josd2
Josephin domain containing 2
chr5_-_145952452 8.401 NM_020582
Atp5j2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
chr7_+_108812146 8.393 NM_009191
Clpb
ClpB caseinolytic peptidase B homolog (E. coli)
chr10_-_117147068 8.390 Mdm2
transformed mouse 3T3 cell double minute 2
chr7_+_150255257 8.307 NM_001115085
NM_020285
NM_138631
Tssc4


tumor-suppressing subchromosomal transferable fragment 4


chr11_+_70783966 8.212 Rpain
RPA interacting protein
chr1_+_192886883 8.200 NM_198654
Nsl1
NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr9_+_13553629 8.181 Mtmr2
myotubularin related protein 2
chr5_-_24083185 8.180 NM_001190443
NM_013853
Abcf2

ATP-binding cassette, sub-family F (GCN20), member 2

chr5_+_34001199 8.165 Tacc3
transforming, acidic coiled-coil containing protein 3
chr3_-_104621135 8.160 NM_001163441
NM_008619
Mov10

Moloney leukemia virus 10

chr17_-_85189893 8.150 Lrpprc
leucine-rich PPR-motif containing
chr1_-_181733742 8.057 Ahctf1
AT hook containing transcription factor 1
chr4_-_116855158 8.039 NM_134471
Kif2c
kinesin family member 2C

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.61 1.52e-32 GO:0044260 cellular macromolecule metabolic process
1.45 2.98e-28 GO:0044237 cellular metabolic process
1.52 1.05e-27 GO:0043170 macromolecule metabolic process
1.40 8.88e-23 GO:0044238 primary metabolic process
1.35 2.67e-21 GO:0008152 metabolic process
1.67 4.98e-19 GO:0090304 nucleic acid metabolic process
1.58 1.30e-17 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64 2.53e-16 GO:0010467 gene expression
1.51 1.48e-15 GO:0034641 cellular nitrogen compound metabolic process
1.49 8.05e-15 GO:0006807 nitrogen compound metabolic process
2.21 1.03e-14 GO:0007049 cell cycle
1.66 2.54e-14 GO:0044267 cellular protein metabolic process
2.50 4.82e-14 GO:0006396 RNA processing
1.61 8.85e-13 GO:0016070 RNA metabolic process
2.65 1.04e-11 GO:0000278 mitotic cell cycle
2.30 1.61e-11 GO:0022402 cell cycle process
1.55 6.82e-11 GO:0034645 cellular macromolecule biosynthetic process
1.55 1.05e-10 GO:0009059 macromolecule biosynthetic process
1.51 2.26e-10 GO:0019538 protein metabolic process
1.73 4.54e-10 GO:0006996 organelle organization
1.45 1.51e-09 GO:0044249 cellular biosynthetic process
1.43 3.51e-09 GO:0009058 biosynthetic process
2.72 4.18e-09 GO:0006397 mRNA processing
2.46 2.97e-08 GO:0016071 mRNA metabolic process
2.30 1.66e-07 GO:0006974 response to DNA damage stimulus
2.62 1.75e-07 GO:0008380 RNA splicing
2.91 3.23e-07 GO:0071843 cellular component biogenesis at cellular level
2.22 5.08e-07 GO:0022403 cell cycle phase
2.93 7.27e-07 GO:0022613 ribonucleoprotein complex biogenesis
2.18 1.93e-06 GO:0044265 cellular macromolecule catabolic process
2.45 2.12e-06 GO:0006281 DNA repair
1.44 8.78e-06 GO:0071841 cellular component organization or biogenesis at cellular level
2.58 1.11e-05 GO:0000087 M phase of mitotic cell cycle
2.41 1.21e-05 GO:0043632 modification-dependent macromolecule catabolic process
2.25 1.25e-05 GO:0000279 M phase
1.12 1.36e-05 GO:0009987 cellular process
2.53 1.95e-05 GO:0048285 organelle fission
2.24 2.08e-05 GO:0051301 cell division
2.00 2.48e-05 GO:0006259 DNA metabolic process
2.37 2.65e-05 GO:0019941 modification-dependent protein catabolic process
2.35 2.88e-05 GO:0051603 proteolysis involved in cellular protein catabolic process
2.38 3.52e-05 GO:0006511 ubiquitin-dependent protein catabolic process
1.35 3.64e-05 GO:0071840 cellular component organization or biogenesis
4.85 4.29e-05 GO:0006261 DNA-dependent DNA replication
2.33 4.87e-05 GO:0006412 translation
2.52 5.11e-05 GO:0000280 nuclear division
2.52 5.11e-05 GO:0007067 mitosis
2.30 5.23e-05 GO:0044257 cellular protein catabolic process
3.80 6.57e-05 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.35 6.89e-05 GO:0071156 regulation of cell cycle arrest
3.54 7.18e-05 GO:0006414 translational elongation
1.47 1.37e-04 GO:0043412 macromolecule modification
3.92 1.58e-04 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.31 1.77e-04 GO:0060255 regulation of macromolecule metabolic process
1.93 2.31e-04 GO:0009057 macromolecule catabolic process
2.83 2.38e-04 GO:0010498 proteasomal protein catabolic process
2.83 2.38e-04 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
3.75 3.54e-04 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
3.16 4.35e-04 GO:0007059 chromosome segregation
1.35 4.51e-04 GO:0010468 regulation of gene expression
3.70 4.57e-04 GO:0051352 negative regulation of ligase activity
3.70 4.57e-04 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.70 4.57e-04 GO:0051444 negative regulation of ubiquitin-protein ligase activity
3.32 5.04e-04 GO:0000075 cell cycle checkpoint
2.14 5.83e-04 GO:0030163 protein catabolic process
1.76 5.96e-04 GO:0033554 cellular response to stress
1.45 8.66e-04 GO:0006464 protein modification process
3.28 1.13e-03 GO:0031397 negative regulation of protein ubiquitination
1.38 1.37e-03 GO:0071842 cellular component organization at cellular level
2.66 1.50e-03 GO:0031396 regulation of protein ubiquitination
3.17 2.10e-03 GO:0051438 regulation of ubiquitin-protein ligase activity
1.83 2.29e-03 GO:0051276 chromosome organization
1.87 2.34e-03 GO:0051726 regulation of cell cycle
1.31 3.04e-03 GO:0016043 cellular component organization
3.11 3.11e-03 GO:0051340 regulation of ligase activity
2.56 3.60e-03 GO:0006260 DNA replication
3.28 3.70e-03 GO:0051443 positive regulation of ubiquitin-protein ligase activity
3.48 5.00e-03 GO:0022618 ribonucleoprotein complex assembly
3.20 5.60e-03 GO:0051351 positive regulation of ligase activity
2.25 6.12e-03 GO:0010564 regulation of cell cycle process
3.43 6.29e-03 GO:0000375 RNA splicing, via transesterification reactions
1.32 6.34e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.81 6.94e-03 GO:0031398 positive regulation of protein ubiquitination
1.24 8.41e-03 GO:0019222 regulation of metabolic process
1.39 1.07e-02 GO:0032774 RNA biosynthetic process
1.60 1.10e-02 GO:0045184 establishment of protein localization
3.28 1.21e-02 GO:0071826 ribonucleoprotein complex subunit organization
2.32 1.44e-02 GO:0034470 ncRNA processing
1.38 1.45e-02 GO:0006351 transcription, DNA-dependent
1.52 1.49e-02 GO:0008104 protein localization
1.25 1.69e-02 GO:0080090 regulation of primary metabolic process
3.28 2.21e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.28 2.21e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
1.58 2.37e-02 GO:0015031 protein transport
1.46 2.38e-02 GO:0033036 macromolecule localization
2.56 2.48e-02 GO:0042254 ribosome biogenesis
1.31 2.68e-02 GO:0051252 regulation of RNA metabolic process
1.29 2.70e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.24 3.09e-02 GO:0031323 regulation of cellular metabolic process
1.28 3.23e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.15 3.53e-02 GO:0007051 spindle organization
2.36 4.01e-02 GO:0000226 microtubule cytoskeleton organization
1.89 4.83e-02 GO:0016568 chromatin modification
2.08 4.87e-02 GO:0034660 ncRNA metabolic process
1.27 4.90e-02 GO:0051171 regulation of nitrogen compound metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.40 2.27e-62 GO:0005622 intracellular
1.40 4.74e-62 GO:0044424 intracellular part
1.46 2.38e-56 GO:0043226 organelle
1.50 3.15e-56 GO:0043227 membrane-bounded organelle
1.45 6.08e-56 GO:0043229 intracellular organelle
1.50 1.39e-55 GO:0043231 intracellular membrane-bounded organelle
1.66 3.47e-42 GO:0005634 nucleus
1.62 3.53e-29 GO:0044446 intracellular organelle part
1.71 6.89e-29 GO:0032991 macromolecular complex
2.04 3.03e-28 GO:0044428 nuclear part
1.60 5.61e-28 GO:0044422 organelle part
1.36 1.13e-26 GO:0005737 cytoplasm
1.96 1.22e-22 GO:0070013 intracellular organelle lumen
1.96 1.59e-22 GO:0043233 organelle lumen
1.94 2.34e-22 GO:0031974 membrane-enclosed lumen
1.98 3.37e-20 GO:0031981 nuclear lumen
2.76 8.48e-18 GO:0030529 ribonucleoprotein complex
1.59 4.33e-16 GO:0043234 protein complex
1.64 4.35e-16 GO:0043228 non-membrane-bounded organelle
1.64 4.35e-16 GO:0043232 intracellular non-membrane-bounded organelle
1.37 7.99e-16 GO:0044444 cytoplasmic part
1.98 1.92e-13 GO:0005654 nucleoplasm
1.12 2.33e-13 GO:0005623 cell
1.12 2.33e-13 GO:0044464 cell part
1.67 6.29e-10 GO:0005739 mitochondrion
2.28 2.89e-09 GO:0005694 chromosome
2.27 2.06e-08 GO:0044427 chromosomal part
3.03 1.22e-07 GO:0005840 ribosome
1.59 1.75e-07 GO:0005829 cytosol
3.04 7.53e-06 GO:0005681 spliceosomal complex
1.82 9.44e-06 GO:0044451 nucleoplasm part
1.87 3.61e-05 GO:0044429 mitochondrial part
2.72 4.01e-04 GO:0000775 chromosome, centromeric region
2.58 5.80e-04 GO:0005759 mitochondrial matrix
1.94 8.89e-04 GO:0005730 nucleolus
1.73 1.16e-03 GO:0015630 microtubule cytoskeleton
2.25 1.52e-03 GO:0000785 chromatin
3.05 2.28e-03 GO:0000776 kinetochore
1.67 2.29e-03 GO:0031975 envelope
3.56 2.40e-03 GO:0000502 proteasome complex
1.67 2.45e-03 GO:0031967 organelle envelope
3.08 3.41e-03 GO:0016585 chromatin remodeling complex
3.88 6.55e-03 GO:0005643 nuclear pore
2.16 7.17e-03 GO:0000228 nuclear chromosome
2.63 2.40e-02 GO:0000793 condensed chromosome
3.80 3.64e-02 GO:0000118 histone deacetylase complex
2.55 3.71e-02 GO:0044455 mitochondrial membrane part
3.12 4.56e-02 GO:0046930 pore complex
2.10 4.58e-02 GO:0044454 nuclear chromosome part
2.44 4.83e-02 GO:0005819 spindle

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.20 2.05e-14 GO:0005488 binding
1.56 5.02e-13 GO:0003676 nucleic acid binding
2.18 7.94e-13 GO:0003723 RNA binding
1.47 2.88e-07 GO:0000166 nucleotide binding
1.24 2.54e-05 GO:0003824 catalytic activity
1.45 6.31e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.43 1.38e-04 GO:0017076 purine nucleotide binding
1.43 1.63e-04 GO:0032555 purine ribonucleotide binding
1.43 1.69e-04 GO:0032553 ribonucleotide binding
2.92 3.44e-04 GO:0003735 structural constituent of ribosome
1.71 7.17e-04 GO:0016462 pyrophosphatase activity
1.70 8.68e-04 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.70 9.24e-04 GO:0016817 hydrolase activity, acting on acid anhydrides
1.45 9.69e-04 GO:0005524 ATP binding
1.71 1.37e-03 GO:0017111 nucleoside-triphosphatase activity
1.43 2.28e-03 GO:0030554 adenyl nucleotide binding
1.42 2.68e-03 GO:0032559 adenyl ribonucleotide binding
2.63 2.25e-02 GO:0016779 nucleotidyltransferase activity
1.33 2.86e-02 GO:0003677 DNA binding
2.92 5.00e-02 GO:0008565 protein transporter activity