• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: bHLH_family.p2

Z-value: 2.198

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_126500607	68.009	NM_009870	Cdk4	cyclin-dependent kinase 4
chr4_+_147965596	28.023	NM_009272	Srm	spermidine synthase
chr17_+_45701100	24.088	NM_028662	Slc35b2	solute carrier family 35, member B2
chr11_+_117670970	23.861	NM_009304	Syngr2	synaptogyrin 2
chr2_-_28771940	22.700	NM_019446 NM_001164186	Barhl1	BarH-like 1 (Drosophila)
chr19_+_7049425	22.289	NM_008889	Ppp1r14b	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_-_60624592	22.026		Shmt1	serine hydroxymethyltransferase 1 (soluble)
chr11_-_60624733	21.743	NM_009171	Shmt1	serine hydroxymethyltransferase 1 (soluble)
chr11_-_99527240	21.498	NM_026834	Krtap4-6	keratin associated protein 4-6
chr3_+_41368801	19.491	NM_001130186	Phf17	PHD finger protein 17
chr15_+_59205752	19.291	NM_001164604 NM_026746	Nsmce2	non-SMC element 2 homolog (MMS21, S. cerevisiae)
chr17_-_45732442	19.076		Slc29a1	solute carrier family 29 (nucleoside transporters), member 1
chr19_-_60656627	18.929	NM_001172096 NM_001172097 NM_030197	2700078E11Rik	RIKEN cDNA 2700078E11 gene
chr17_+_45700882	18.871		Slc35b2	solute carrier family 35, member B2
chrX_-_131076136	18.612	NM_013898	Timm8a1	translocase of inner mitochondrial membrane 8 homolog a1 (yeast)
chr9_+_21172314	18.490	NM_001042707 NM_001042708 NM_001042709 NM_010561	Ilf3	interleukin enhancer binding factor 3
chr10_+_79317316	18.298	NM_001077363 NM_008956	Ptbp1	polypyrimidine tract binding protein 1
chr11_+_99725789	18.270	NM_001177484	Gm11559	predicted gene 11559
chr17_+_29627950	18.254	NM_008842	Pim1	proviral integration site 1
chr19_+_7049639	17.043		Ppp1r14b	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_-_35137799	16.862		D17H6S56E-5	DNA segment, Chr 17, human D6S56E 5
chr14_+_51544629	16.839	NM_009687	Apex1	apurinic/apyrimidinic endonuclease 1
chr9_+_107490100	16.837		Ifrd2	interferon-related developmental regulator 2
chr11_-_99489523	16.828	NM_001048196	Krtap4-1	keratin associated protein 4-1
chr5_-_138613028	16.531	NM_008568	Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)
chr17_+_46633703	16.487	NM_207161	BC048355	cDNA sequence BC048355
chr10_+_79317396	16.265		Ptbp1	polypyrimidine tract binding protein 1
chr17_+_35137995	15.991		Vars	valyl-tRNA synthetase
chr9_-_43047862	15.863	NM_178644	Oaf	OAF homolog (Drosophila)
chr18_+_56867378	15.661	NM_010721	Lmnb1	lamin B1
chr2_+_31325763	15.531	NM_007494	Ass1	argininosuccinate synthetase 1
chr8_+_87514471	15.331	NM_001167991 NM_133255	Hook2	hook homolog 2 (Drosophila)
chr1_-_188573165	15.310	NM_026041	Rrp15	ribosomal RNA processing 15 homolog (S. cerevisiae)
chr11_-_76031013	15.165	NM_177367	Gemin4	gem (nuclear organelle) associated protein 4
chr15_-_38230397	15.103	NM_013692	Klf10	Kruppel-like factor 10
chr14_-_32643594	15.083	NM_001024604	Ankrd28	ankyrin repeat domain 28
chr7_-_52722144	15.048	NM_007527	Bax	BCL2-associated X protein
chr15_-_59205688	15.005	NM_153548	E430025E21Rik	RIKEN cDNA E430025E21 gene
chr7_-_29096957	14.990	NM_025616	Timm50	translocase of inner mitochondrial membrane 50 homolog (yeast)
chr9_+_35075447	14.982	NM_028040	Rpusd4	RNA pseudouridylate synthase domain containing 4
chr11_+_69814046	14.909	NM_007888	Dvl2	dishevelled 2, dsh homolog (Drosophila)
chr16_+_20672847	14.872		Eif4g1	eukaryotic translation initiation factor 4, gamma 1
chr3_+_41368846	14.694		Phf17	PHD finger protein 17
chr7_+_54051432	14.589	NM_008186	Gtf2h1	general transcription factor II H, polypeptide 1
chr5_-_137755406	14.500	NM_011639	Trip6	thyroid hormone receptor interactor 6
chr11_+_74462965	14.483	NM_001081158	1300001I01Rik	RIKEN cDNA 1300001I01 gene
chr5_-_137755361	14.259		Trip6	thyroid hormone receptor interactor 6
chr13_-_104899571	14.234	NM_029447	Nln	neurolysin (metallopeptidase M3 family)
chr17_+_35137851	14.232	NM_011690	Vars	valyl-tRNA synthetase
chr19_+_46130978	14.224	NM_001081214	Pprc1	peroxisome proliferative activated receptor, gamma, coactivator-related 1
chr4_-_41222121	14.097	NM_026872	Ubap2	ubiquitin-associated protein 2
chr2_+_31325818	14.049		Ass1	argininosuccinate synthetase 1
chr9_+_107489981	13.675	NM_025903	Ifrd2	interferon-related developmental regulator 2
chr2_-_164658954	13.630	NM_001082974	Neurl2	neuralized-like 2 (Drosophila)
chr17_-_12962478	13.622	NM_010515	Igf2r	insulin-like growth factor 2 receptor
chr6_-_49164952	13.577	NM_023670	Igf2bp3	insulin-like growth factor 2 mRNA binding protein 3
chr17_+_29628249	13.345		Pim1	proviral integration site 1
chr4_-_118966829	13.287		Ybx1	Y box protein 1
chr4_+_122960527	13.275	NM_148917	Pabpc4	poly(A) binding protein, cytoplasmic 4
chr15_-_78603874	13.200	NM_008595	Mfng	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr10_-_62801726	13.141	NM_001159590 NM_019812 NM_001159589	Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)
chr3_+_67386633	13.098	NM_025813	Mfsd1	major facilitator superfamily domain containing 1
chr8_+_77617514	13.065	NM_010442	Hmox1	heme oxygenase (decycling) 1
chr19_-_24355054	12.936	NM_008044	Fxn	frataxin
chr1_+_71603729	12.857	NM_026195	Atic	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr15_+_34012415	12.671	NM_026002	Mtdh	metadherin
chr2_-_104582953	12.469	NM_144804	Depdc7	DEP domain containing 7
chr1_-_155179844	12.294	NM_010683	Lamc1	laminin, gamma 1
chr17_-_25097542	12.181	NM_198937	Hn1l	hematological and neurological expressed 1-like
chr8_+_77617542	12.179		Hmox1	heme oxygenase (decycling) 1
chr9_-_107192018	12.129		Mapkapk3	mitogen-activated protein kinase-activated protein kinase 3
chr12_+_17551678	12.112	NM_013614	Odc1	ornithine decarboxylase, structural 1
chr4_-_133574655	12.060	NM_145833	Lin28a	lin-28 homolog A (C. elegans)
chr8_-_72498125	12.007		Gatad2a	GATA zinc finger domain containing 2A
chr3_+_87710282	11.975		Hdgf	hepatoma-derived growth factor
chr9_+_21216277	11.917	NM_021888	Qtrt1	queuine tRNA-ribosyltransferase 1
chr10_+_122116022	11.833
chr7_-_52241669	11.806	NM_019830	Prmt1	protein arginine N-methyltransferase 1
chr11_+_120494714	11.656
chr7_-_152125823	11.635	NM_007631	Ccnd1	cyclin D1
chr16_-_5204078	11.613	NM_013796	Nagpa	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr16_-_5204069	11.608		Nagpa	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr17_+_35031503	11.550	NM_198886	Zbtb12	zinc finger and BTB domain containing 12
chr17_-_53828596	11.536	NM_028232	Sgol1	shugoshin-like 1 (S. pombe)
chr4_+_109349189	11.530	NM_007983	Faf1	Fas-associated factor 1
chr4_-_86315874	11.482	NM_007408	Plin2	perilipin 2
chr3_-_89856250	11.467	NM_001165983 NM_001165985 NM_001165987 NM_028475 NM_153489 NM_001165984 NM_001165986 NM_001165988	Ubap2l	ubiquitin associated protein 2-like
chr19_-_45824047	11.449	NM_008723	Npm3	nucleoplasmin 3
chr1_+_174430359	11.415	NM_178598	Tagln2	transgelin 2
chr5_-_77380593	11.378	NM_172146	Ppat	phosphoribosyl pyrophosphate amidotransferase
chr16_+_20672854	11.349		Eif4g1	eukaryotic translation initiation factor 4, gamma 1
chr6_-_49164469	11.199		Igf2bp3	insulin-like growth factor 2 mRNA binding protein 3
chr4_+_109349259	11.081		Faf1	Fas-associated factor 1
chr12_+_17551771	11.071		Odc1	ornithine decarboxylase, structural 1
chr3_+_88336316	11.070	NM_001029890	Mex3a	mex3 homolog A (C. elegans)
chr19_-_4201541	11.044	NM_011237	Rad9	RAD9 homolog (S. pombe)
chr2_-_154394864	10.931		E2f1	E2F transcription factor 1
chr11_+_72254841	10.884	NM_016776	Mybbp1a	MYB binding protein (P160) 1a
chr5_+_45884612	10.786	NM_024434	Lap3	leucine aminopeptidase 3
chr1_+_59741800	10.701	NM_018868	Nop58	NOP58 ribonucleoprotein homolog (yeast)
chr7_-_152125661	10.642		Ccnd1	cyclin D1
chr17_-_56419388	10.546		Plin3	perilipin 3
chr7_+_26444141	10.481	NM_138586	Exosc5	exosome component 5
chr16_+_20672770	10.368	NM_001005331 NM_145941	Eif4g1	eukaryotic translation initiation factor 4, gamma 1
chr1_-_55144637	10.315		Hspd1	heat shock protein 1 (chaperonin)
chr2_-_72931338	10.315
chr15_+_98860321	10.123	NM_009448	Tuba1c	tubulin, alpha 1C
chr2_-_104656852	10.031	NM_001123327	Qser1	glutamine and serine rich 1
chr4_-_41688124	10.015	NM_011014	Sigmar1	sigma non-opioid intracellular receptor 1
chr1_-_95375363	9.985		Hdlbp	high density lipoprotein (HDL) binding protein
chr17_+_71965554	9.926	NM_175639	Wdr43	WD repeat domain 43
chr2_-_103601232	9.919	NM_153126	Nat10	N-acetyltransferase 10
chr3_+_80840575	9.890		Pdgfc	platelet-derived growth factor, C polypeptide
chr11_+_3190334	9.870	NM_019574	Patz1	POZ (BTB) and AT hook containing zinc finger 1
chr16_-_30388534	9.674	NM_001128094 NM_001128096	Atp13a3	ATPase type 13A3
chr9_-_106340536	9.515		Acy1	aminoacylase 1
chr11_-_69485842	9.471	NM_001159375 NM_144958	Eif4a1	eukaryotic translation initiation factor 4A1
chr9_-_106340564	9.395	NM_025371	Acy1	aminoacylase 1
chr16_-_57606866	9.394	NM_025599	2610528E23Rik	RIKEN cDNA 2610528E23 gene
chr6_-_6167086	9.382		Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr16_+_32608981	9.355	NM_011638	Tfrc	transferrin receptor
chr11_-_69485800	9.338		Eif4a1	eukaryotic translation initiation factor 4A1
chr6_-_6167113	9.296	NM_001177572 NM_015829	Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr5_+_93522440	9.292	NM_001009818	Sept11	septin 11
chr11_-_115971327	9.264	NM_172570	Trim47	tripartite motif-containing 47
chr17_-_33783578	9.234		Hnrnpm	heterogeneous nuclear ribonucleoprotein M
chr7_+_129210847	9.144		Ubfd1	ubiquitin family domain containing 1
chr17_-_32525894	9.089	NM_011717	Wiz	widely-interspaced zinc finger motifs
chr2_-_84510822	9.059	NM_001033166 NM_001037279	2700094K13Rik	RIKEN cDNA 2700094K13 gene
chr16_+_20672890	9.048		Eif4g1	eukaryotic translation initiation factor 4, gamma 1
chr17_-_45739015	9.003	NM_001177468 NM_001177469	Gm7325	predicted gene 7325
chr10_+_17443024	8.990	NM_010828	Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr17_-_45738863	8.967	NM_001177470	Gm7325	predicted gene 7325
chr3_+_137527448	8.959	NM_016750	H2afz	H2A histone family, member Z
chr6_-_6167034	8.956		Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr7_-_129164546	8.950	NM_028758	Gga2	golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr18_+_35713033	8.921		Matr3	matrin 3
chr7_+_148662315	8.865		Tspan4	tetraspanin 4
chr7_+_148662278	8.863		Tspan4	tetraspanin 4
chr17_-_35137690	8.830		D17H6S56E-5	DNA segment, Chr 17, human D6S56E 5
chr8_+_86247034	8.799
chr15_-_102087673	8.780	NM_011244	Rarg	retinoic acid receptor, gamma
chr19_+_6276885	8.735	NM_010119	Ehd1	EH-domain containing 1
chr11_-_95867076	8.701	NM_009951	Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1
chr3_+_80840609	8.567		Pdgfc	platelet-derived growth factor, C polypeptide
chr9_+_44134859	8.560	NM_007875	Dpagt1	dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr8_-_119517339	8.549	NM_026572	Gcsh	glycine cleavage system protein H (aminomethyl carrier)
chr4_-_55545337	8.546	NM_010637	Klf4	Kruppel-like factor 4 (gut)
chr11_+_99734702	8.497	NM_015741	Krtap9-1	keratin associated protein 9-1
chrX_+_156065141	8.495	NM_001135727	Sh3kbp1	SH3-domain kinase binding protein 1
chr15_+_34012606	8.459		Mtdh	metadherin
chr1_-_13650563	8.370	NM_145381	Lactb2	lactamase, beta 2
chr8_+_67471046	8.338	NM_001163747 NM_028427	Tmem192	transmembrane protein 192
chr15_-_102181072	8.335	NM_153416	Aaas	achalasia, adrenocortical insufficiency, alacrimia
chr4_-_147462051	8.310	NM_009642	Agtrap	angiotensin II, type I receptor-associated protein
chr8_+_120022149	8.303	NM_172285	Plcg2	phospholipase C, gamma 2
chr2_+_132672645	8.297		Crls1	cardiolipin synthase 1
chr11_+_57822347	8.268	NM_028451	Larp1	La ribonucleoprotein domain family, member 1
chr16_+_44139908	8.266	NM_028108	Naa50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr8_-_126545208	8.265	NM_133966	Taf5l	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr3_-_89197124	8.242	NM_009565	Zbtb7b	zinc finger and BTB domain containing 7B
chr3_+_152059620	8.242	NM_198416	Zzz3	zinc finger, ZZ domain containing 3
chr11_-_99520272	8.238	NM_001126320	Gm11563	predicted gene 11563
chr7_+_129210948	8.227		Ubfd1	ubiquitin family domain containing 1
chr5_-_77380189	8.192		Ppat	phosphoribosyl pyrophosphate amidotransferase
chr19_+_6276685	8.178		Ehd1	EH-domain containing 1
chr7_+_129210954	8.129		Ubfd1	ubiquitin family domain containing 1
chr11_-_120685418	8.128		Fasn	fatty acid synthase
chr11_+_72263260	8.126
chr19_-_42203380	8.082	NM_027106	Avpi1	arginine vasopressin-induced 1
chr10_+_43198945	8.069	NM_199028	Bend3	BEN domain containing 3
chr11_+_69393851	8.029	NM_001127233 NM_011640	Trp53	transformation related protein 53
chr11_-_120685366	8.011		Fasn	fatty acid synthase
chr17_-_24300592	7.934	NM_172935	Amdhd2	amidohydrolase domain containing 2
chr9_+_83728331	7.932		Ttk	Ttk protein kinase
chr8_+_87396009	7.893	NM_001168246 NM_027954 NM_001168244	Syce2	synaptonemal complex central element protein 2
chr3_+_40754552	7.864	NM_001040399	Larp1b	La ribonucleoprotein domain family, member 1B
chr10_-_119913990	7.860	NM_010441	Hmga2	high mobility group AT-hook 2
chr9_+_83728295	7.843	NM_001110265 NM_009445	Ttk	Ttk protein kinase
chr7_+_35904310	7.737	NM_007678	Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha
chr1_-_55144687	7.692	NM_010477	Hspd1	heat shock protein 1 (chaperonin)
chrX_+_12858142	7.669	NM_010028	Ddx3x	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr4_-_133801438	7.635	NM_024215	Zfp593	zinc finger protein 593
chr11_-_67735654	7.592	NM_173754	Usp43	ubiquitin specific peptidase 43
chr17_+_46909583	7.562	NM_025966	2310039H08Rik	RIKEN cDNA 2310039H08 gene
chr16_+_35770488	7.552		Hspbap1	Hspb associated protein 1
chr1_-_75176965	7.469		Abcb6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_+_132672362	7.404	NM_001024385	Crls1	cardiolipin synthase 1
chr7_+_148656507	7.401		Cd151	CD151 antigen
chr17_-_56256668	7.361	NM_001077348	Plin5	perilipin 5
chr2_+_122060526	7.328	NM_146126	Sord	sorbitol dehydrogenase
chr13_+_73901101	7.326	NM_011390	Slc12a7	solute carrier family 12, member 7
chr5_-_77380226	7.268		Ppat	phosphoribosyl pyrophosphate amidotransferase
chr17_-_47748155	7.254		Bysl	bystin-like
chr1_+_55145132	7.183		Hspe1	heat shock protein 1 (chaperonin 10)
chr2_-_160191800	7.177		Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr2_-_92210955	7.164	NM_001166633 NM_172670	Gyltl1b	glycosyltransferase-like 1B
chr18_+_14941735	7.161	NM_001100449	Taf4b	TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr14_-_99498905	7.135	NM_028315	Dis3	DIS3 mitotic control homolog (S. cerevisiae)
chr14_-_31832165	7.119		Gnl3	guanine nucleotide binding protein-like 3 (nucleolar)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.37	1.93e-47	GO:0044238	primary metabolic process
1.33	4.25e-47	GO:0008152	metabolic process
1.37	4.28e-46	GO:0044237	cellular metabolic process
1.56	2.39e-40	GO:0009058	biosynthetic process
1.55	4.34e-38	GO:0044249	cellular biosynthetic process
1.39	1.04e-33	GO:0044260	cellular macromolecule metabolic process
1.36	3.60e-33	GO:0043170	macromolecule metabolic process
1.47	1.16e-32	GO:0034641	cellular nitrogen compound metabolic process
1.57	1.22e-32	GO:0010467	gene expression
1.45	1.29e-31	GO:0006807	nitrogen compound metabolic process
1.48	2.09e-30	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56	4.83e-29	GO:0034645	cellular macromolecule biosynthetic process
1.55	8.23e-29	GO:0009059	macromolecule biosynthetic process
1.51	2.98e-27	GO:0090304	nucleic acid metabolic process
1.55	3.25e-27	GO:0016070	RNA metabolic process
1.49	6.21e-26	GO:0031326	regulation of cellular biosynthetic process
1.48	8.16e-26	GO:0009889	regulation of biosynthetic process
1.49	1.01e-25	GO:0010468	regulation of gene expression
1.41	2.32e-25	GO:0031323	regulation of cellular metabolic process
1.51	2.62e-25	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.37	1.97e-24	GO:0019222	regulation of metabolic process
1.49	2.55e-24	GO:0010556	regulation of macromolecule biosynthetic process
1.40	4.12e-24	GO:0080090	regulation of primary metabolic process
1.50	1.96e-22	GO:0051252	regulation of RNA metabolic process
1.40	2.14e-22	GO:0060255	regulation of macromolecule metabolic process
1.50	7.52e-22	GO:0006355	regulation of transcription, DNA-dependent
1.44	4.27e-21	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44	4.80e-21	GO:0051171	regulation of nitrogen compound metabolic process
1.57	1.27e-20	GO:0032774	RNA biosynthetic process
1.57	1.62e-20	GO:0006351	transcription, DNA-dependent
1.71	1.75e-16	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.34	5.33e-15	GO:0032502	developmental process
1.36	1.59e-13	GO:0048518	positive regulation of biological process
1.38	1.86e-13	GO:0048522	positive regulation of cellular process
1.34	2.70e-13	GO:0007275	multicellular organismal development
1.65	3.17e-13	GO:0031328	positive regulation of cellular biosynthetic process
1.85	8.62e-13	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.45	1.09e-12	GO:0048513	organ development
1.35	1.16e-12	GO:0048856	anatomical structure development
1.69	1.55e-12	GO:0009790	embryo development
1.62	2.06e-12	GO:0009891	positive regulation of biosynthetic process
1.71	3.19e-12	GO:0045893	positive regulation of transcription, DNA-dependent
1.39	3.81e-12	GO:0048523	negative regulation of cellular process
1.65	3.82e-12	GO:0010557	positive regulation of macromolecule biosynthetic process
1.69	8.55e-12	GO:0051254	positive regulation of RNA metabolic process
1.11	8.76e-12	GO:0009987	cellular process
1.65	1.03e-11	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.63	1.37e-11	GO:0051173	positive regulation of nitrogen compound metabolic process
1.65	2.49e-11	GO:0010628	positive regulation of gene expression
1.50	4.13e-11	GO:0031325	positive regulation of cellular metabolic process
1.36	6.54e-11	GO:0048519	negative regulation of biological process
1.67	9.94e-11	GO:0009890	negative regulation of biosynthetic process
1.35	1.14e-10	GO:0048731	system development
1.67	1.28e-10	GO:0031327	negative regulation of cellular biosynthetic process
1.68	2.71e-10	GO:0010558	negative regulation of macromolecule biosynthetic process
1.57	3.45e-10	GO:0010605	negative regulation of macromolecule metabolic process
1.54	5.44e-10	GO:0009892	negative regulation of metabolic process
1.81	6.00e-10	GO:0009792	embryo development ending in birth or egg hatching
1.68	6.33e-10	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.46	6.48e-10	GO:0009893	positive regulation of metabolic process
1.94	6.62e-10	GO:0007389	pattern specification process
1.81	8.47e-10	GO:0043009	chordate embryonic development
1.48	1.35e-09	GO:0010604	positive regulation of macromolecule metabolic process
1.45	4.39e-09	GO:0009653	anatomical structure morphogenesis
2.06	4.76e-09	GO:0001501	skeletal system development
1.36	5.29e-09	GO:0048869	cellular developmental process
1.41	6.37e-09	GO:0044281	small molecule metabolic process
1.65	6.72e-09	GO:0010629	negative regulation of gene expression
1.53	7.49e-09	GO:0031324	negative regulation of cellular metabolic process
1.36	9.61e-09	GO:0030154	cell differentiation
1.28	1.10e-08	GO:0071840	cellular component organization or biogenesis
1.55	2.73e-08	GO:0009888	tissue development
2.39	2.90e-08	GO:0048705	skeletal system morphogenesis
2.05	2.94e-08	GO:0003002	regionalization
1.66	3.16e-08	GO:0051253	negative regulation of RNA metabolic process
1.81	3.76e-08	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.66	4.23e-08	GO:0009887	organ morphogenesis
1.65	1.30e-07	GO:0045892	negative regulation of transcription, DNA-dependent
1.58	5.95e-07	GO:0051172	negative regulation of nitrogen compound metabolic process
1.50	6.21e-07	GO:0042127	regulation of cell proliferation
2.16	8.57e-07	GO:0009952	anterior/posterior pattern formation
1.98	8.75e-07	GO:0061061	muscle structure development
1.58	1.05e-06	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.84	1.11e-06	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
2.15	1.45e-06	GO:0022613	ribonucleoprotein complex biogenesis
2.10	2.37e-06	GO:0071843	cellular component biogenesis at cellular level
1.72	3.03e-06	GO:0048598	embryonic morphogenesis
1.29	3.91e-06	GO:0071841	cellular component organization or biogenesis at cellular level
1.25	3.99e-06	GO:0016043	cellular component organization
1.46	4.08e-06	GO:0044085	cellular component biogenesis
1.44	5.83e-06	GO:0050793	regulation of developmental process
1.87	6.65e-06	GO:0048568	embryonic organ development
1.72	7.97e-06	GO:0032583	regulation of gene-specific transcription
1.28	1.19e-05	GO:0044267	cellular protein metabolic process
1.25	1.52e-05	GO:0019538	protein metabolic process
1.70	1.58e-05	GO:0009719	response to endogenous stimulus
1.85	2.00e-05	GO:0006412	translation
2.28	3.16e-05	GO:0042254	ribosome biogenesis
1.42	3.41e-05	GO:0010941	regulation of cell death
2.13	3.46e-05	GO:0048545	response to steroid hormone stimulus
2.71	4.94e-05	GO:0048704	embryonic skeletal system morphogenesis
1.42	5.38e-05	GO:0042981	regulation of apoptosis
1.42	5.78e-05	GO:0043067	regulation of programmed cell death
1.99	9.59e-05	GO:0048562	embryonic organ morphogenesis
2.47	1.37e-04	GO:0045787	positive regulation of cell cycle
1.67	3.18e-04	GO:0009725	response to hormone stimulus
1.45	3.75e-04	GO:0045595	regulation of cell differentiation
1.55	4.23e-04	GO:0048646	anatomical structure formation involved in morphogenesis
2.01	5.23e-04	GO:0007517	muscle organ development
1.28	6.28e-04	GO:0065008	regulation of biological quality
1.71	6.30e-04	GO:0045596	negative regulation of cell differentiation
2.00	6.56e-04	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
2.34	7.09e-04	GO:0048706	embryonic skeletal system development
1.42	7.38e-04	GO:0048468	cell development
1.24	2.53e-03	GO:0071842	cellular component organization at cellular level
2.85	2.60e-03	GO:0043401	steroid hormone mediated signaling pathway
1.75	2.88e-03	GO:0010608	posttranscriptional regulation of gene expression
1.89	3.19e-03	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
1.84	3.53e-03	GO:0032582	negative regulation of gene-specific transcription
1.78	3.75e-03	GO:0043193	positive regulation of gene-specific transcription
1.81	4.02e-03	GO:0071495	cellular response to endogenous stimulus
2.01	4.50e-03	GO:0006417	regulation of translation
1.38	5.03e-03	GO:2000026	regulation of multicellular organismal development
2.27	5.14e-03	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.50	5.67e-03	GO:0008284	positive regulation of cell proliferation
1.59	5.98e-03	GO:0048729	tissue morphogenesis
2.36	6.05e-03	GO:0006403	RNA localization
1.63	6.66e-03	GO:0035295	tube development
1.53	6.98e-03	GO:0044283	small molecule biosynthetic process
2.22	7.02e-03	GO:0030879	mammary gland development
2.37	7.78e-03	GO:0050657	nucleic acid transport
2.37	7.78e-03	GO:0050658	RNA transport
2.37	7.78e-03	GO:0051236	establishment of RNA localization
1.69	7.83e-03	GO:0040007	growth
1.85	9.03e-03	GO:0034470	ncRNA processing
2.90	1.06e-02	GO:0017148	negative regulation of translation
1.43	1.19e-02	GO:0033554	cellular response to stress
2.41	1.64e-02	GO:0071383	cellular response to steroid hormone stimulus
1.71	2.34e-02	GO:0034660	ncRNA metabolic process
1.73	2.40e-02	GO:0048732	gland development
1.49	2.43e-02	GO:0071310	cellular response to organic substance
1.30	2.66e-02	GO:0033036	macromolecule localization
1.61	2.66e-02	GO:0001701	in utero embryonic development
2.16	2.71e-02	GO:0006662	glycerol ether metabolic process
1.46	2.72e-02	GO:0072358	cardiovascular system development
1.46	2.72e-02	GO:0072359	circulatory system development
1.58	3.08e-02	GO:0044271	cellular nitrogen compound biosynthetic process
2.66	3.21e-02	GO:0034329	cell junction assembly
1.54	3.30e-02	GO:0051093	negative regulation of developmental process
1.42	3.56e-02	GO:0006915	apoptosis
1.49	3.69e-02	GO:0043066	negative regulation of apoptosis
1.41	3.82e-02	GO:0012501	programmed cell death
1.35	3.89e-02	GO:0022607	cellular component assembly
2.36	4.04e-02	GO:0009755	hormone-mediated signaling pathway
2.36	4.04e-02	GO:0048771	tissue remodeling
1.48	4.11e-02	GO:0043069	negative regulation of programmed cell death
1.43	4.27e-02	GO:0071844	cellular component assembly at cellular level
2.11	4.55e-02	GO:0018904	organic ether metabolic process
1.23	4.68e-02	GO:0043412	macromolecule modification
4.56	4.99e-02	GO:0031365	N-terminal protein amino acid modification

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.29	5.69e-79	GO:0005622	intracellular
1.29	9.97e-77	GO:0044424	intracellular part
1.33	2.91e-69	GO:0043226	organelle
1.33	1.97e-68	GO:0043229	intracellular organelle
1.34	4.45e-63	GO:0043227	membrane-bounded organelle
1.34	5.24e-63	GO:0043231	intracellular membrane-bounded organelle
1.42	4.71e-43	GO:0005634	nucleus
1.28	1.74e-41	GO:0005737	cytoplasm
1.64	2.20e-26	GO:0031974	membrane-enclosed lumen
1.64	4.81e-26	GO:0043233	organelle lumen
1.64	6.24e-26	GO:0070013	intracellular organelle lumen
1.30	7.62e-26	GO:0044444	cytoplasmic part
1.36	5.45e-25	GO:0044422	organelle part
1.60	1.19e-24	GO:0044428	nuclear part
1.35	1.61e-23	GO:0044446	intracellular organelle part
1.64	2.09e-22	GO:0031981	nuclear lumen
1.33	3.08e-15	GO:0032991	macromolecular complex
1.65	3.58e-15	GO:0005654	nucleoplasm
1.08	6.82e-14	GO:0005623	cell
1.08	6.82e-14	GO:0044464	cell part
1.45	4.09e-11	GO:0005739	mitochondrion
1.31	6.83e-11	GO:0043234	protein complex
1.68	1.06e-10	GO:0044451	nucleoplasm part
1.93	1.71e-10	GO:0005730	nucleolus
1.31	2.33e-09	GO:0043228	non-membrane-bounded organelle
1.31	2.33e-09	GO:0043232	intracellular non-membrane-bounded organelle
1.39	4.36e-08	GO:0005829	cytosol
1.53	1.23e-05	GO:0031967	organelle envelope
1.52	1.96e-05	GO:0031975	envelope
1.73	4.19e-05	GO:0005667	transcription factor complex
1.68	1.71e-04	GO:0042598	vesicular fraction
1.55	1.86e-04	GO:0030529	ribonucleoprotein complex
1.69	2.06e-04	GO:0005792	microsome
1.90	2.59e-04	GO:0005635	nuclear envelope
1.35	3.14e-04	GO:0005783	endoplasmic reticulum
1.43	5.97e-03	GO:0044429	mitochondrial part
1.29	6.42e-03	GO:0000267	cell fraction
2.63	1.50e-02	GO:0005643	nuclear pore
2.37	1.65e-02	GO:0046930	pore complex
1.33	2.53e-02	GO:0012505	endomembrane system

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.20	9.44e-35	GO:0005488	binding
1.53	9.43e-30	GO:0003676	nucleic acid binding
1.89	9.02e-21	GO:0001071	nucleic acid binding transcription factor activity
1.89	9.02e-21	GO:0003700	sequence-specific DNA binding transcription factor activity
1.72	9.98e-17	GO:0030528	transcription regulator activity
1.50	1.61e-16	GO:0003677	DNA binding
1.86	1.71e-16	GO:0043565	sequence-specific DNA binding
1.24	1.11e-15	GO:0005515	protein binding
1.23	1.04e-13	GO:0003824	catalytic activity
1.68	3.88e-11	GO:0003723	RNA binding
1.34	1.64e-06	GO:0046914	transition metal ion binding
1.79	7.04e-06	GO:0008134	transcription factor binding
2.48	1.89e-05	GO:0008135	translation factor activity, nucleic acid binding
1.75	2.98e-05	GO:0016564	transcription repressor activity
1.26	3.28e-05	GO:0000166	nucleotide binding
1.71	5.07e-05	GO:0016563	transcription activator activity
1.41	2.10e-04	GO:0019899	enzyme binding
1.28	2.73e-04	GO:0016740	transferase activity
1.19	2.79e-04	GO:0043169	cation binding
1.18	2.87e-04	GO:0043167	ion binding
1.32	2.90e-04	GO:0008270	zinc ion binding
1.18	5.03e-04	GO:0046872	metal ion binding
2.74	1.55e-03	GO:0004879	ligand-dependent nuclear receptor activity
1.41	1.63e-03	GO:0046983	protein dimerization activity
1.22	1.96e-03	GO:0016787	hydrolase activity
2.58	2.26e-03	GO:0003743	translation initiation factor activity
2.68	4.31e-03	GO:0003707	steroid hormone receptor activity
1.77	4.72e-03	GO:0003682	chromatin binding
1.23	9.52e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.74	1.10e-02	GO:0043566	structure-specific DNA binding
1.73	1.67e-02	GO:0010843	promoter binding
1.22	1.77e-02	GO:0032555	purine ribonucleotide binding
1.22	1.86e-02	GO:0032553	ribonucleotide binding
1.22	1.91e-02	GO:0017076	purine nucleotide binding
2.01	4.92e-02	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity