Motif ID: JUN.p2

Z-value: 4.028


Transcription factors associated with JUN.p2:

Gene SymbolEntrez IDGene Name
JUN 3725 jun oncogene
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
JUNhg19_v1_chr1_-_59249687_592497840.576.2e-04Click!
JUNDhg19_v1_chr19_-_18392413_183924350.327.8e-02Click!
JUNBhg19_v1_chr19_+_12902295_12902332-0.134.9e-01Click!


Activity profile for motif JUN.p2.

activity profile for motif JUN.p2


Sorted Z-values histogram for motif JUN.p2

Sorted Z-values for motif JUN.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of JUN.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_-_44258210 24.498 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr19_-_50979461 19.909 FAM71E1
family with sequence similarity 71, member E1
chr19_+_36024313 14.816 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr6_+_97010423 12.628 NM_001170807
NM_020482
FHL5

four and a half LIM domains 5

chr2_+_232457574 11.781 NM_152614
C2orf57
chromosome 2 open reading frame 57
chr11_-_5531152 10.691 NM_017481
UBQLN3
ubiquilin 3
chr20_+_33146500 10.435 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr4_-_186456580 10.431 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr19_+_49109999 9.615 NM_133498
SPACA4
sperm acrosome associated 4
chr11_-_119187811 8.678 NM_006500
MCAM
melanoma cell adhesion molecule
chr1_+_110655061 8.664 NM_203412
UBL4B
ubiquitin-like 4B
chr11_+_12695851 8.562 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr5_-_112770537 8.536 NM_032028
TSSK1B
testis-specific serine kinase 1B
chr11_-_1593149 8.455 NM_004420
DUSP8
dual specificity phosphatase 8
chr12_-_13256572 8.078 NM_001080554
NM_001080555
NM_001206842
GSG1


germ cell associated 1


chr9_-_27297106 7.999 NM_001161585
NM_020641
C9orf11

chromosome 9 open reading frame 11

chr14_+_93389491 7.966 CHGA
chromogranin A (parathyroid secretory protein 1)
chr21_-_45079327 7.423 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr2_-_211168315 7.361 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr11_-_107582733 7.228 NM_003063
SLN
sarcolipin
chr6_+_118869441 7.184 NM_002667
PLN
phospholamban
chr17_+_48585912 7.180 MYCBPAP
MYCBP associated protein
chr9_+_105757592 7.116 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr17_+_48585744 7.103 NM_032133
MYCBPAP
MYCBP associated protein
chr19_+_11649578 7.102 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr3_+_156544075 7.074 NM_001004316
NM_001193283
LEKR1

leucine, glutamate and lysine rich 1

chr6_+_117586720 6.972 NM_153453
NM_182645
VGLL2

vestigial like 2 (Drosophila)

chr13_+_113030650 6.969 NM_145248
SPACA7
sperm acrosome associated 7
chr9_-_19033183 6.954 NM_153707
FAM154A
family with sequence similarity 154, member A
chr19_+_44220213 6.882 NM_019612
IRGC
immunity-related GTPase family, cinema
chr20_-_44420538 6.629 NM_080614
WFDC3
WAP four-disulfide core domain 3
chr2_+_97001506 6.542 NCAPH
non-SMC condensin I complex, subunit H
chr12_-_4754275 6.479 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr1_+_153175918 6.436 NM_001010857
LELP1
late cornified envelope-like proline-rich 1
chr2_+_220408742 6.434 NM_001005209
TMEM198
transmembrane protein 198
chr7_+_123295860 6.396 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr20_+_5891973 6.386 NM_001819
CHGB
chromogranin B (secretogranin 1)
chr20_+_10199455 6.370 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr7_+_142636602 6.309 NM_178829
C7orf34
chromosome 7 open reading frame 34
chr19_-_50980002 6.297 NM_138411
FAM71E1
family with sequence similarity 71, member E1
chr17_+_39994042 6.258 NM_152467
KLHL10
kelch-like 10 (Drosophila)
chr6_-_15248886 6.211


chr9_+_17578952 6.153 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr9_-_34397786 6.107 NM_032596
C9orf24
chromosome 9 open reading frame 24
chr2_+_220283098 6.019 NM_001927
DES
desmin
chr3_+_158288952 6.014 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr19_-_36036390 5.913 LOC100506469
uncharacterized LOC100506469
chr1_+_167064086 5.903 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr5_+_174151531 5.856 NM_002449
MSX2
msh homeobox 2
chr1_-_162346579 5.774 NM_182581
C1orf111
chromosome 1 open reading frame 111
chr14_+_21498344 5.765 NM_173846
TPPP2
tubulin polymerization-promoting protein family member 2
chr3_+_107096187 5.693 NM_032600
CCDC54
coiled-coil domain containing 54
chr19_+_18723666 5.544 NM_012109
TMEM59L
transmembrane protein 59-like
chr20_+_55099784 5.520 NM_001012971
FAM209A
FAM209B
family with sequence similarity 209, member A
family with sequence similarity 209, member B
chr19_-_49250023 5.485 NM_182575
IZUMO1
izumo sperm-egg fusion 1
chr5_+_118965253 5.455 NM_001163991
NM_182761
FAM170A

family with sequence similarity 170, member A

chr7_-_45128492 5.407 NM_001146334
NACAD
NAC alpha domain containing
chr14_+_88851987 5.364 NM_001040428
NM_018418
SPATA7

spermatogenesis associated 7

chr1_+_85527992 5.327 NM_145172
WDR63
WD repeat domain 63
chr9_+_36169384 5.322 NM_005893
CCIN
calicin
chr7_-_37956377 5.321 SFRP4
secreted frizzled-related protein 4
chr4_-_111544206 5.319 NM_000325
PITX2
paired-like homeodomain 2
chr4_+_75480628 5.286 NM_001657
AREG
amphiregulin
chr4_-_111558150 5.203 PITX2
paired-like homeodomain 2
chr3_+_44803280 5.181 KIF15
kinesin family member 15
chr11_-_64851556 5.147 NM_080668
CDCA5
cell division cycle associated 5
chr12_+_54378929 5.118 NM_017409
HOXC10
homeobox C10
chr20_+_32250089 5.105 NM_080825
C20orf144
chromosome 20 open reading frame 144
chr22_+_50528307 5.097 NM_001164104
NM_018995
MOV10L1

Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)

chr3_+_139654001 5.091 NM_022131
CLSTN2
calsyntenin 2
chr9_+_111624545 5.035 NM_006687
ACTL7A
actin-like 7A
chr20_+_17207680 5.022 PCSK2
proprotein convertase subtilisin/kexin type 2
chr9_-_111618209 5.021 NM_006686
ACTL7B
actin-like 7B
chr1_-_154127591 4.980 NM_001159484
NM_207308
NUP210L

nucleoporin 210kDa-like

chr14_+_93389444 4.949 NM_001275
CHGA
chromogranin A (parathyroid secretory protein 1)
chr1_+_99729847 4.900 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chrX_+_89176939 4.892 NM_138960
TGIF2LX
TGFB-induced factor homeobox 2-like, X-linked
chr8_+_103563847 4.828 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr10_+_22634373 4.800 NM_001253854
NM_001253855
NM_012443
NM_172242
SPAG6



sperm associated antigen 6



chr11_-_119234628 4.787 USP2
ubiquitin specific peptidase 2
chr1_+_99730067 4.756 LPPR4
lipid phosphate phosphatase-related protein type 4
chr2_+_149632772 4.736 NM_004522
KIF5C
kinesin family member 5C
chr11_-_68780667 4.705 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr19_-_36246411 4.698 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr16_+_30034654 4.678 NM_001109659
NM_001109660
C16orf92

chromosome 16 open reading frame 92

chr19_+_6135650 4.667 NM_030924
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chrY_+_3447081 4.646 NM_139214
TGIF2LY
TGFB-induced factor homeobox 2-like, Y-linked
chr6_+_126661221 4.637 NM_001012507
CENPW
centromere protein W
chr13_-_36871968 4.631 NM_001198910
NM_001144981
NM_001144982
NM_001144983
NM_001144984
NM_001144985
NM_001144986
NM_001198908
CCDC169-SOHLH2
CCDC169






CCDC169-SOHLH2 readthrough
coiled-coil domain containing 169






chrX_+_83116153 4.610 NM_021118
CYLC1
cylicin, basic protein of sperm head cytoskeleton 1
chr10_-_128209996 4.596 NM_001004298
C10orf90
chromosome 10 open reading frame 90
chr6_-_127780534 4.532 NM_014702
KIAA0408
KIAA0408
chr14_+_88852065 4.517 SPATA7
spermatogenesis associated 7
chr7_-_37956515 4.468 NM_003014
SFRP4
secreted frizzled-related protein 4
chr11_-_119234859 4.443 NM_171997
USP2
ubiquitin specific peptidase 2
chr16_+_2016874 4.442 NM_174903
RNF151
ring finger protein 151
chr14_-_94443065 4.410 NM_001202429
ASB2
ankyrin repeat and SOCS box containing 2
chr15_-_83240499 4.385 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr7_+_28448970 4.365 LOC401317
uncharacterized LOC401317
chr19_-_8809054 4.356 NM_178525
ACTL9
actin-like 9
chr4_+_128802064 4.339 NM_001190801
PLK4
polo-like kinase 4
chr3_-_51909599 4.320 NM_001145059
IQCF5
IQ motif containing F5
chr1_+_152850797 4.308 NM_030663
SMCP
sperm mitochondria-associated cysteine-rich protein
chr16_-_46782104 4.290 NM_182493
MYLK3
myosin light chain kinase 3
chr5_+_121495870 4.289 NM_001195535
LOC100505841
zinc finger protein 474-like
chr17_+_33448597 4.278 NM_017559
FNDC8
fibronectin type III domain containing 8
chr16_-_3545420 4.260 NM_001080524
C16orf90
chromosome 16 open reading frame 90
chr20_+_17207596 4.245 NM_001201529
NM_002594
PCSK2

proprotein convertase subtilisin/kexin type 2

chr14_+_77292714 4.225 NM_194287
C14orf166B
chromosome 14 open reading frame 166B
chr3_+_44803208 4.219 NM_020242
KIF15
kinesin family member 15
chr11_-_62457001 4.198 LRRN4CL
LRRN4 C-terminal like
chr19_+_5455411 4.181 NM_181710
ZNRF4
zinc and ring finger 4
chr9_+_134165075 4.149 NM_032728
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr4_+_75310852 4.148 NM_001657
AREG
amphiregulin
chr4_+_128802015 4.118 NM_001190799
NM_014264
PLK4

polo-like kinase 4

chrX_-_49965657 4.102 NM_003886
AKAP4
A kinase (PRKA) anchor protein 4
chr19_-_36246206 4.101 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr17_+_42385780 4.098 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr7_+_73275488 4.080 NM_182504
WBSCR28
Williams-Beuren syndrome chromosome region 28
chr2_-_27362277 4.060 NM_178553
C2orf53
chromosome 2 open reading frame 53
chr17_+_41857802 4.055 NM_001136483
C17orf105
chromosome 17 open reading frame 105
chr1_-_205391180 4.051 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr7_+_128312345 4.019 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr20_-_35201677 4.016


chrX_-_139047676 4.015 NM_001013403
CXorf66
chromosome X open reading frame 66
chr6_+_26204779 4.012 NM_003545
HIST1H4E
histone cluster 1, H4e
chr5_+_71403040 4.000 NM_005909
MAP1B
microtubule-associated protein 1B
chr8_-_95274540 3.992 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr8_-_95274520 3.969 GEM
GTP binding protein overexpressed in skeletal muscle
chr12_-_50790391 3.950 NM_001145475
FAM186A
family with sequence similarity 186, member A
chr1_+_1115076 3.945 NM_153254
TTLL10
tubulin tyrosine ligase-like family, member 10
chr1_+_40713572 3.931 NM_001008740
TMCO2
transmembrane and coiled-coil domains 2
chr14_+_101292451 3.906 MEG3
maternally expressed 3 (non-protein coding)
chr4_+_175839508 3.897 NM_001130703
NM_001130704
NM_001130705
NM_014269
ADAM29



ADAM metallopeptidase domain 29



chr6_-_37225360 3.893 NM_145316
TMEM217
transmembrane protein 217
chr13_-_36871882 3.872 CCDC169
coiled-coil domain containing 169
chr9_-_33402505 3.853 NM_001170
AQP7
aquaporin 7
chr20_+_18794369 3.850 NM_178483
C20orf79
chromosome 20 open reading frame 79
chr2_+_231860838 3.847 NM_139073
SPATA3
spermatogenesis associated 3
chr5_-_95768660 3.833 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chrY_-_20935503 3.829 NM_001001877
NM_153716
NM_152584
NM_033108
HSFY2

HSFY1

heat shock transcription factor, Y linked 2

heat shock transcription factor, Y-linked 1

chr17_+_61562177 3.825 NM_001178057
NM_152830
ACE

angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

chr2_-_241759627 3.804 NM_001244008
NM_004321
KIF1A

kinesin family member 1A

chr1_-_21044202 3.793 NM_001122819
NM_020816
KIF17

kinesin family member 17

chr16_+_56225301 3.790 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chrY_+_20708556 3.775 NM_153716
NM_001001877
NM_033108
NM_152584
HSFY2

HSFY1

heat shock transcription factor, Y linked 2

heat shock transcription factor, Y-linked 1

chr4_+_120056938 3.727 NM_016599
MYOZ2
myozenin 2
chr19_-_57352055 3.719 NM_001146326
NM_001146327
NM_015363
NM_001146184
NM_001146185
NM_001146187
NM_006210
ZIM2


PEG3



zinc finger, imprinted 2


paternally expressed 3



chr17_-_34270670 3.698 NM_001199951
LYZL6
lysozyme-like 6
chr1_-_76397975 3.690 NM_080868
ASB17
ankyrin repeat and SOCS box containing 17
chr3_+_42190825 3.686 TRAK1
trafficking protein, kinesin binding 1
chr4_+_113739203 3.674 NM_001127493
ANK2
ankyrin 2, neuronal
chr12_+_48876285 3.673 NM_152319
C12orf54
chromosome 12 open reading frame 54
chr22_+_41957011 3.647 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr13_+_111973014 3.634 NM_152324
C13orf16
chromosome 13 open reading frame 16
chr7_+_151653463 3.615 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr3_+_125688027 3.613 NM_001012337
ROPN1B
rhophilin associated tail protein 1B
chr1_+_212209112 3.590 DTL
denticleless homolog (Drosophila)
chrX_+_84498993 3.583 NM_021998
ZNF711
zinc finger protein 711
chr12_+_18891040 3.574 NM_033328
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr1_+_212209129 3.573 DTL
denticleless homolog (Drosophila)
chr4_+_119809978 3.560 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr3_+_8543508 3.539 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr11_-_9025531 3.526 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr11_-_111782447 3.514 NM_001885
CRYAB
crystallin, alpha B
chr19_-_35719578 3.513 NM_152481
FAM187B
family with sequence similarity 187, member B
chrX_-_132091223 3.511 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr3_-_51937336 3.505 NM_152397
IQCF1
IQ motif containing F1
chr20_+_43344005 3.502 WISP2
WNT1 inducible signaling pathway protein 2
chr17_+_37821598 3.487 NM_003673
TCAP
titin-cap (telethonin)
chr3_+_139654206 3.480 CLSTN2
calsyntenin 2
chr7_-_122342965 3.463 NM_198085
RNF148
ring finger protein 148
chr22_+_51176623 3.458 NM_001097
ACR
acrosin
chr5_+_162887516 3.446 NM_001142556
NM_001142557
NM_012484
NM_012485
HMMR



hyaluronan-mediated motility receptor (RHAMM)



chr3_+_50297644 3.445


chr9_-_129884885 3.432 ANGPTL2
angiopoietin-like 2
chr10_+_13203547 3.409 NM_018518
NM_182751
MCM10

minichromosome maintenance complex component 10

chr10_-_131762374 3.408 EBF3
early B-cell factor 3
chr3_-_42452022 3.406 NM_144634
LYZL4
lysozyme-like 4
chr1_-_228604305 3.402 TRIM17
tripartite motif containing 17
chr18_+_77866914 3.399 NM_014913
ADNP2
ADNP homeobox 2
chr11_+_6226797 3.397 NM_173525
C11orf42
chromosome 11 open reading frame 42
chr5_+_94727047 3.392 NM_152548
FAM81B
family with sequence similarity 81, member B
chrX_-_13835187 3.392 GPM6B
glycoprotein M6B
chr1_+_212208918 3.384 NM_016448
DTL
denticleless homolog (Drosophila)
chr11_-_62457370 3.370 NM_203422
LRRN4CL
LRRN4 C-terminal like
chr4_-_104119475 3.370 NM_001813
CENPE
centromere protein E, 312kDa
chr14_-_44976452 3.358 NM_032135
FSCB
fibrous sheath CABYR binding protein
chr20_-_31592231 3.335 NM_080675
SUN5
Sad1 and UNC84 domain containing 5
chr2_-_232790958 3.331 NM_024409
NPPC
natriuretic peptide C
chr7_+_128355425 3.328 NM_032599
FAM71F1
family with sequence similarity 71, member F1
chr20_+_17680592 3.322 NM_001014977
NM_178477
BANF2

barrier to autointegration factor 2

chr9_-_33402583 3.321 AQP7
aquaporin 7
chr18_-_77439739 3.305 FLJ25715
uncharacterized protein FLJ25715
chr1_-_235812994 3.287 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr9_-_127533397 3.268 NM_001489
NM_033334
NR6A1

nuclear receptor subfamily 6, group A, member 1

chr2_+_149632836 3.267 KIF5C
kinesin family member 5C
chr1_+_201159952 3.259 NM_001164586
IGFN1
immunoglobulin-like and fibronectin type III domain containing 1
chr17_+_79885567 3.245 LOC92659
uncharacterized LOC92659
chr3_+_11267666 3.245 NM_001098211
HRH1
histamine receptor H1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.61 1.43e-07 GO:0007283 spermatogenesis
3.61 1.43e-07 GO:0048232 male gamete generation
3.02 4.48e-07 GO:0019953 sexual reproduction
2.88 1.13e-06 GO:0032504 multicellular organism reproduction
2.88 1.13e-06 GO:0048609 multicellular organismal reproductive process
1.77 2.78e-05 GO:0030154 cell differentiation
2.89 4.52e-05 GO:0007276 gamete generation
1.72 1.05e-04 GO:0048869 cellular developmental process
3.09 1.93e-04 GO:0044057 regulation of system process
1.50 4.25e-04 GO:0007275 multicellular organismal development
1.45 8.83e-04 GO:0032502 developmental process
11.35 2.04e-03 GO:0030317 sperm motility
1.32 1.28e-02 GO:0032501 multicellular organismal process
1.91 1.31e-02 GO:0022414 reproductive process
1.90 1.53e-02 GO:0000003 reproduction
4.93 1.79e-02 GO:0090257 regulation of muscle system process
3.45 2.39e-02 GO:0006936 muscle contraction
1.46 3.03e-02 GO:0048731 system development
5.01 3.83e-02 GO:0006937 regulation of muscle contraction
1.67 4.06e-02 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.80 8.08e-05 GO:0005856 cytoskeleton
7.40 1.66e-04 GO:0019861 flagellum
4.52 2.64e-04 GO:0044449 contractile fiber part
4.15 7.82e-04 GO:0043292 contractile fiber
8.01 1.17e-03 GO:0009434 microtubule-based flagellum
4.52 1.38e-03 GO:0030017 sarcomere
4.11 1.87e-03 GO:0030016 myofibril
34.05 6.06e-03 GO:0033150 cytoskeletal calyx
3.07 6.34e-03 GO:0030141 stored secretory granule
1.87 9.68e-03 GO:0042995 cell projection
6.05 1.05e-02 GO:0001669 acrosomal vesicle
1.98 1.53e-02 GO:0015630 microtubule cytoskeleton
25.54 2.37e-02 GO:0033011 perinuclear theca
1.41 3.16e-02 GO:0043228 non-membrane-bounded organelle
1.41 3.16e-02 GO:0043232 intracellular non-membrane-bounded organelle
8.96 4.27e-02 GO:0005871 kinesin complex

Nothing significant found in function category.