Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 1.996


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ARNT2hg19_v1_chr15_+_80733579_807336310.551.0e-03Click!
AHRhg19_v1_chr7_+_17338182_17338357-0.271.3e-01Click!
ARNThg19_v1_chr1_-_150849062_1508491100.058.1e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_104178900 6.660 NM_002779
 PSD
pleckstrin and Sec7 domain containing
chr10_-_104178569 5.540 PSD
pleckstrin and Sec7 domain containing
chr22_+_42372763 5.339 NM_019106
NM_145733
 SEPT3

septin 3

chr10_+_105344714 4.931 NEURL
neuralized homolog (Drosophila)
chr9_-_34589679 4.043 NM_001842
NM_147164
 CNTFR

ciliary neurotrophic factor receptor

chr6_+_73331808 3.819 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr6_-_6007632 3.606 NM_016588
 NRN1
neuritin 1
chr19_-_18314731 3.530 NM_002866
 RAB3A
RAB3A, member RAS oncogene family
chr9_-_34590137 3.460 NM_001207011
 CNTFR
ciliary neurotrophic factor receptor
chrX_-_152939256 3.236 PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr7_+_128470462 3.137 NM_001127487
NM_001458
 FLNC

filamin C, gamma

chr2_+_220283098 3.092 NM_001927
 DES
desmin
chr5_-_172755418 3.067 STC2
stanniocalcin 2
chr3_-_184870727 3.021 NM_001025266
 C3orf70
chromosome 3 open reading frame 70
chr16_+_6069094 2.942 NM_001142333
NM_018723
 RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chr5_-_172755195 2.939 STC2
stanniocalcin 2
chr17_+_43971868 2.876 MAPT
microtubule-associated protein tau
chr17_+_43972014 2.838 MAPT
microtubule-associated protein tau
chr13_+_21277481 2.734 NM_138284
 IL17D
interleukin 17D
chr17_+_43971655 2.731 NM_001123066
NM_001123067
NM_001203251
NM_001203252
NM_005910
NM_016834
NM_016835
NM_016841
 MAPT







microtubule-associated protein tau








Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
143.12 3.33e-02 GO:0006540 glutamate decarboxylation to succinate
42.94 2.64e-02 GO:0006105 succinate metabolic process
6.11 1.68e-06 GO:0007268 synaptic transmission
5.76 1.37e-06 GO:0019226 transmission of nerve impulse
5.76 1.37e-06 GO:0035637 multicellular organismal signaling
4.39 6.96e-06 GO:0007267 cell-cell signaling
3.95 3.68e-02 GO:0009628 response to abiotic stimulus
3.63 4.42e-05 GO:0007154 cell communication
3.12 1.15e-02 GO:0048468 cell development
2.82 7.65e-04 GO:0007399 nervous system development
2.32 3.72e-02 GO:0003008 system process
2.03 1.04e-02 GO:0048731 system development
1.93 2.11e-03 GO:0023052 signaling
1.93 1.85e-02 GO:0048856 anatomical structure development
1.86 2.49e-02 GO:0007275 multicellular organismal development
1.76 5.62e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
Enrichment   P-value GO Accession GO Term
53.67 2.26e-03 GO:0061200 clathrin sculpted gamma-aminobutyric acid transport vesicle
53.67 2.26e-03 GO:0061202 clathrin sculpted gamma-aminobutyric acid transport vesicle membrane
35.79 8.69e-03 GO:0060198 clathrin sculpted vesicle
8.43 3.99e-02 GO:0030665 clathrin coated vesicle membrane
8.23 4.44e-02 GO:0008021 synaptic vesicle
5.90 2.36e-02 GO:0043025 neuronal cell body
5.73 2.83e-02 GO:0044297 cell body
5.70 2.93e-02 GO:0030424 axon
5.47 6.85e-04 GO:0044456 synapse part
5.17 6.60e-05 GO:0045202 synapse
5.00 1.02e-02 GO:0030659 cytoplasmic vesicle membrane
4.87 3.40e-04 GO:0043005 neuron projection
4.83 1.33e-02 GO:0012506 vesicle membrane
4.61 8.06e-03 GO:0044433 cytoplasmic vesicle part
1.97 3.70e-02 GO:0044459 plasma membrane part
1.68 1.43e-02 GO:0005886 plasma membrane
1.66 2.04e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
20.45 7.04e-03 GO:0008066 glutamate receptor activity