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Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 1.996

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_-_104178900	6.660	NM_002779	PSD	pleckstrin and Sec7 domain containing
chr10_-_104178569	5.540		PSD	pleckstrin and Sec7 domain containing
chr22_+_42372763	5.339	NM_019106 NM_145733	SEPT3	septin 3
chr10_+_105344714	4.931		NEURL	neuralized homolog (Drosophila)
chr9_-_34589679	4.043	NM_001842 NM_147164	CNTFR	ciliary neurotrophic factor receptor
chr6_+_73331808	3.819		KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5
chr6_-_6007632	3.606	NM_016588	NRN1	neuritin 1
chr19_-_18314731	3.530	NM_002866	RAB3A	RAB3A, member RAS oncogene family
chr9_-_34590137	3.460	NM_001207011	CNTFR	ciliary neurotrophic factor receptor
chrX_-_152939256	3.236		PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr7_+_128470462	3.137	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr2_+_220283098	3.092	NM_001927	DES	desmin
chr5_-_172755418	3.067		STC2	stanniocalcin 2
chr3_-_184870727	3.021	NM_001025266	C3orf70	chromosome 3 open reading frame 70
chr16_+_6069094	2.942	NM_001142333 NM_018723	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_-_172755195	2.939		STC2	stanniocalcin 2
chr17_+_43971868	2.876		MAPT	microtubule-associated protein tau
chr17_+_43972014	2.838		MAPT	microtubule-associated protein tau
chr13_+_21277481	2.734	NM_138284	IL17D	interleukin 17D
chr17_+_43971655	2.731	NM_001123066 NM_001123067 NM_001203251 NM_001203252 NM_005910 NM_016834 NM_016835 NM_016841	MAPT	microtubule-associated protein tau
chr13_-_36705432	2.668		DCLK1	doublecortin-like kinase 1
chr15_-_79382839	2.634		RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1
chr1_-_13840157	2.547	NM_001010847	LRRC38	leucine rich repeat containing 38
chrX_+_38420690	2.483	NM_004615	TSPAN7	tetraspanin 7
chr15_+_84116172	2.482		SH3GL3	SH3-domain GRB2-like 3
chr6_-_127840499	2.441	NM_001012279	C6orf174	chromosome 6 open reading frame 174
chr15_-_79383080	2.405	NM_001145648 NM_002891	RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1
chr6_+_73331570	2.389	NM_001160130 NM_001160132 NM_001160133 NM_001160134 NM_019842	KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5
chr12_-_16758839	2.304	NM_001243612	LMO3	LIM domain only 3 (rhombotin-like 2)
chr19_-_19006868	2.281	NM_021267 NM_198207 NM_001492	CERS1 GDF1	ceramide synthase 1 growth differentiation factor 1
chr6_+_73331992	2.258		KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5
chr19_-_47164289	2.190	NM_145056	DACT3	dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr5_-_134369571	2.139		PITX1	paired-like homeodomain 1
chr10_+_60936346	2.118	NM_032439	PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like
chr12_+_54943358	2.100		PDE1B	phosphodiesterase 1B, calmodulin-dependent
chr2_+_220299699	2.076	NM_005876	SPEG	SPEG complex locus
chr8_+_85095501	2.013	NM_173848	RALYL	RALY RNA binding protein-like
chr22_-_19511777	2.001		CLDN5	claudin 5
chr13_+_51796363	1.965	NM_001242312 NM_145019	FAM124A	family with sequence similarity 124A
chr9_+_87283453	1.949	NM_001018064 NM_006180	NTRK2	neurotrophic tyrosine kinase, receptor, type 2
chr3_+_35681008	1.938		ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr1_+_86046434	1.922	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr9_+_87284733	1.912		NTRK2	neurotrophic tyrosine kinase, receptor, type 2
chr15_+_84115979	1.910	NM_003027	SH3GL3	SH3-domain GRB2-like 3
chr4_-_168155732	1.883	NM_001040159 NM_001204352 NM_001204354 NM_001204355 NM_001204356 NM_001204358 NM_001251967 NM_016950	SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr10_+_105253734	1.840	NM_004210	NEURL	neuralized homolog (Drosophila)
chr11_+_112832089	1.817		NCAM1	neural cell adhesion molecule 1
chr9_+_87284625	1.785	NM_001007097	NTRK2	neurotrophic tyrosine kinase, receptor, type 2
chr3_-_149688886	1.776		PFN2	profilin 2
chr17_-_8059637	1.768		PER1	period homolog 1 (Drosophila)
chr1_+_201252579	1.768	NM_000299 NM_001005337	PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
chr10_-_60936189	1.751
chr11_+_112831968	1.747	NM_000615 NM_001076682 NM_001242607 NM_001242608 NM_181351	NCAM1	neural cell adhesion molecule 1
chr13_-_36705513	1.735	NM_004734	DCLK1	doublecortin-like kinase 1
chr7_-_44365019	1.731	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr4_-_168155576	1.729	NM_001204353	SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr3_-_149688638	1.726	NM_002628 NM_053024	PFN2	profilin 2
chr5_-_134914447	1.724		CXCL14	chemokine (C-X-C motif) ligand 14
chr17_-_40333190	1.706	NM_012285	KCNH4	potassium voltage-gated channel, subfamily H (eag-related), member 4
chr12_-_16759430	1.694		LMO3	LIM domain only 3 (rhombotin-like 2)
chr3_+_6902797	1.678	NM_000844 NM_181874	GRM7	glutamate receptor, metabotropic 7
chr3_+_134514044	1.668	NM_004441	EPHB1	EPH receptor B1
chr3_-_151987332	1.666		LOC401093	uncharacterized LOC401093
chrX_-_152938742	1.663	NM_001135740	PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chrX_-_128788913	1.663	NM_017413	APLN	apelin
chr8_+_85095452	1.653	NM_001100392 NM_001100393	RALYL	RALY RNA binding protein-like
chr17_-_74236272	1.649	NM_052916	RNF157	ring finger protein 157
chr17_+_4487833	1.628	NM_001114974	SMTNL2	smoothelin-like 2
chr19_-_11565612	1.624
chr17_+_43971998	1.614		MAPT	microtubule-associated protein tau
chr12_+_103351451	1.602	NM_004316	ASCL1	achaete-scute complex homolog 1 (Drosophila)
chr4_-_168155691	1.600		SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr12_-_16759420	1.593		LMO3	LIM domain only 3 (rhombotin-like 2)
chr2_-_45236521	1.563	NM_016932	SIX2	SIX homeobox 2
chr13_-_36705466	1.561		DCLK1	doublecortin-like kinase 1
chr16_+_22825806	1.557	NM_006043	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr17_+_41177247	1.553	NM_005440	RND2	Rho family GTPase 2
chr11_+_112832201	1.550		NCAM1	neural cell adhesion molecule 1
chr3_-_184870627	1.547		C3orf70	chromosome 3 open reading frame 70
chr1_+_110693131	1.543	NM_001010898	SLC6A17	solute carrier family 6, member 17
chr1_-_38512446	1.540	NM_002699	POU3F1	POU class 3 homeobox 1
chr11_+_112832281	1.538		NCAM1	neural cell adhesion molecule 1
chr14_+_33408458	1.532	NM_001164749 NM_001165893 NM_022123 NM_173159	NPAS3	neuronal PAS domain protein 3
chr5_+_151151511	1.529		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr4_+_94750041	1.513	NM_005172	ATOH1	atonal homolog 1 (Drosophila)
chr3_+_134514300	1.492		EPHB1	EPH receptor B1
chr3_+_10857867	1.490	NM_014229	SLC6A11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr10_+_23983674	1.489	NM_001098500	KIAA1217	KIAA1217
chr6_-_40555111	1.489	NM_020737	LRFN2	leucine rich repeat and fibronectin type III domain containing 2
chrX_+_21392396	1.449	NM_001168647 NM_001168648 NM_001168649 NM_014927	CNKSR2	connector enhancer of kinase suppressor of Ras 2
chr4_+_81118639	1.437	NM_001099403	PRDM8	PR domain containing 8
chr7_+_113726364	1.430		FOXP2	forkhead box P2
chrX_-_128977291	1.413	NM_001008222	ZDHHC9	zinc finger, DHHC-type containing 9
chr6_+_126070724	1.391	NM_012259	HEY2	hairy/enhancer-of-split related with YRPW motif 2
chr2_+_171673071	1.388	NM_000817 NM_013445	GAD1	glutamate decarboxylase 1 (brain, 67kDa)
chr8_-_26371387	1.378	NM_007257	PNMA2	paraneoplastic antigen MA2
chr20_-_50384899	1.370	NM_006045	ATP9A	ATPase, class II, type 9A
chr20_-_50384861	1.365		ATP9A	ATPase, class II, type 9A
chr1_+_77748286	1.346	NM_012093	AK5	adenylate kinase 5
chr22_-_39548448	1.345	NM_175709	CBX7	chromobox homolog 7
chr11_+_17757494	1.345	NM_001112741 NM_004976	KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1
chr1_+_109642814	1.341		SCARNA2	small Cajal body-specific RNA 2
chr10_+_26505593	1.339		GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr20_-_3154169	1.337		ProSAPiP1	ProSAPiP1 protein
chr8_+_85095702	1.330		RALYL	RALY RNA binding protein-like
chr21_-_40032563	1.330	NM_001243428	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr19_-_38747171	1.327	NM_001243947 NM_033256	PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr20_+_34680569	1.306		EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr6_+_126070813	1.294		HEY2	hairy/enhancer-of-split related with YRPW motif 2
chr18_-_35145603	1.294		CELF4	CUGBP, Elav-like family member 4
chr17_+_7554711	1.292		ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr5_+_42423811	1.276	NM_000163	GHR	growth hormone receptor
chr12_+_54943176	1.276	NM_000924	PDE1B	phosphodiesterase 1B, calmodulin-dependent
chr7_+_54610018	1.258	NM_182546	VSTM2A	V-set and transmembrane domain containing 2A
chr11_-_35440514	1.229		SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr4_-_105412466	1.214	NM_025212	CXXC4	CXXC finger protein 4
chr12_-_88974094	1.206	NM_000899 NM_003994	KITLG	KIT ligand
chr3_-_160822625	1.203	NM_033169 NM_001038628 NM_003781 NM_033167 NM_033168	B3GALNT1	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr3_+_6902812	1.202		GRM7	glutamate receptor, metabotropic 7
chr14_-_35183722	1.194	NM_001243645 NM_138638	CFL2	cofilin 2 (muscle)
chr9_-_101470836	1.193	NM_005458	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
chr22_-_19512001	1.189		CLDN5	claudin 5
chr3_-_62359189	1.184	NM_018008	FEZF2	FEZ family zinc finger 2
chr14_-_94254765	1.183	NM_178013	PRIMA1	proline rich membrane anchor 1
chr10_-_105452878	1.170		SH3PXD2A	SH3 and PX domains 2A
chr1_+_150336989	1.167	NM_015203	RPRD2	regulation of nuclear pre-mRNA domain containing 2
chr1_+_77747727	1.166		AK5	adenylate kinase 5
chrX_+_152954965	1.160	NM_001142806	SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr1_-_205649616	1.159	NM_033102	SLC45A3	solute carrier family 45, member 3
chr5_-_172756505	1.147	NM_003714	STC2	stanniocalcin 2
chr5_+_151151483	1.146		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr10_+_60936508	1.140		PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like
chr2_+_206547131	1.136	NM_003872 NM_018534 NM_201264 NM_201266 NM_201267 NM_201279	NRP2	neuropilin 2
chr16_+_22825481	1.135		HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr16_+_24267672	1.127		CACNG3	calcium channel, voltage-dependent, gamma subunit 3
chr16_-_86542463	1.125		LOC400550	uncharacterized LOC400550
chr21_+_47744032	1.121	NM_006031	PCNT	pericentrin
chr8_+_120885899	1.120	NM_022783	DEPTOR	DEP domain containing MTOR-interacting protein
chr4_-_5894695	1.116	NM_001014809	CRMP1	collapsin response mediator protein 1
chr1_+_145472454	1.115		ANKRD34A	ankyrin repeat domain 34A
chr19_-_38746978	1.115		PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr13_-_84456473	1.102	NM_052910	SLITRK1	SLIT and NTRK-like family, member 1
chr7_+_97361270	1.099	NM_003182 NM_013996 NM_013997 NM_013998	TAC1	tachykinin, precursor 1
chr7_+_98246595	1.096	NM_002523	NPTX2	neuronal pentraxin II
chr9_+_140033588	1.095	NM_000832 NM_001185090 NM_001185091 NM_007327 NM_021569	GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr4_-_154710207	1.089	NM_003013	SFRP2	secreted frizzled-related protein 2
chr1_+_218519576	1.083		TGFB2	transforming growth factor, beta 2
chr9_-_140196702	1.079	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr17_+_72427535	1.075	NM_022036	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr12_-_22487566	1.065	NM_003034	ST8SIA1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr14_-_81687574	1.061	NM_201595	GTF2A1	general transcription factor IIA, 1, 19/37kDa
chrX_-_140271275	1.058		LDOC1	leucine zipper, down-regulated in cancer 1
chr15_-_41166336	1.056	NM_133639	RHOV	ras homolog gene family, member V
chr1_-_37499708	1.052	NM_000831	GRIK3	glutamate receptor, ionotropic, kainate 3
chr13_-_40177304	1.040		LHFP	lipoma HMGIC fusion partner
chr2_-_119916338	1.039	NM_182528	C1QL2	complement component 1, q subcomponent-like 2
chr11_+_107462073	1.035		ELMOD1	ELMO/CED-12 domain containing 1
chr11_+_107461807	1.035	NM_001130037 NM_018712	ELMOD1	ELMO/CED-12 domain containing 1
chr11_-_1593149	1.034	NM_004420	DUSP8	dual specificity phosphatase 8
chr11_+_107461955	1.032		ELMOD1	ELMO/CED-12 domain containing 1
chr17_-_38256905	1.031	NM_021724	NR1D1	nuclear receptor subfamily 1, group D, member 1
chr16_+_67197287	1.026	NM_001040667 NM_001538	HSF4	heat shock transcription factor 4
chr16_-_70713927	1.021		MTSS1L	metastasis suppressor 1-like
chr13_-_44361032	1.021	NM_001242863 NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr9_-_35689902	1.018	NM_003289 NM_213674	TPM2	tropomyosin 2 (beta)
chrX_-_128977719	1.017	NM_016032	ZDHHC9	zinc finger, DHHC-type containing 9
chr9_+_71939487	1.016	NM_001127608	FAM189A2	family with sequence similarity 189, member A2
chr15_-_63673918	1.013		CA12	carbonic anhydrase XII
chr11_-_17498322	1.010		ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr1_+_41249479	1.010	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chr1_+_77747602	1.007	NM_174858	AK5	adenylate kinase 5
chr6_+_24126349	1.002	NM_080723	NRSN1	neurensin 1
chr9_+_103115342	1.000
chr3_-_49449400	0.999		RHOA	ras homolog gene family, member A
chrX_+_130192215	0.999	NM_144967	ARHGAP36	Rho GTPase activating protein 36
chr14_-_61115906	0.999	NM_005982	SIX1	SIX homeobox 1
chr20_+_56964289	0.996		VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr11_-_18813127	0.994	NM_001039970 NM_006906 NM_032781	PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr9_-_79520878	0.985	NM_015225	PRUNE2	prune homolog 2 (Drosophila)
chr8_-_80679897	0.984	NM_001040708 NM_012258	HEY1	hairy/enhancer-of-split related with YRPW motif 1
chr17_+_45772629	0.983	NM_014726	TBKBP1	TBK1 binding protein 1
chr17_-_38256548	0.978		NR1D1	nuclear receptor subfamily 1, group D, member 1
chr5_-_176057324	0.978	NM_001001502 NM_003085	SNCB	synuclein, beta
chr7_+_86274076	0.970		GRM3	glutamate receptor, metabotropic 3
chr1_-_205649537	0.969		SLC45A3	solute carrier family 45, member 3
chr3_+_39851028	0.968	NM_015460	MYRIP	myosin VIIA and Rab interacting protein
chr1_+_227127959	0.967		ADCK3	aarF domain containing kinase 3
chr4_+_20255234	0.964	NM_004787	SLIT2	slit homolog 2 (Drosophila)
chr16_-_77468930	0.962	NM_199355	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr2_+_29338207	0.960	NM_024692	CLIP4	CAP-GLY domain containing linker protein family, member 4
chr2_+_153191830	0.953		FMNL2	formin-like 2
chr11_-_86383355	0.953	NM_006680	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial
chr18_-_35145999	0.951	NM_001025087 NM_001025088 NM_001025089 NM_020180	CELF4	CUGBP, Elav-like family member 4
chr10_+_71211215	0.947	NM_012339	TSPAN15	tetraspanin 15
chr16_+_82660641	0.946		CDH13	cadherin 13, H-cadherin (heart)
chr6_-_146056372	0.940		EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr8_+_68864589	0.939	NM_024870 NM_025170	PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr6_-_105584982	0.936	NM_001199563	BVES	blood vessel epicardial substance
chr6_-_146056654	0.926		EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr1_-_17445865	0.925	NM_007365	PADI2	peptidyl arginine deiminase, type II

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
5.76	1.37e-06	GO:0019226	transmission of nerve impulse
5.76	1.37e-06	GO:0035637	multicellular organismal signaling
6.11	1.68e-06	GO:0007268	synaptic transmission
4.39	6.96e-06	GO:0007267	cell-cell signaling
3.63	4.42e-05	GO:0007154	cell communication
1.76	5.62e-04	GO:0032501	multicellular organismal process
2.82	7.65e-04	GO:0007399	nervous system development
1.93	2.11e-03	GO:0023052	signaling
2.03	1.04e-02	GO:0048731	system development
3.12	1.15e-02	GO:0048468	cell development
1.93	1.85e-02	GO:0048856	anatomical structure development
1.86	2.49e-02	GO:0007275	multicellular organismal development
42.94	2.64e-02	GO:0006105	succinate metabolic process
143.12	3.33e-02	GO:0006540	glutamate decarboxylation to succinate
3.95	3.68e-02	GO:0009628	response to abiotic stimulus
2.32	3.72e-02	GO:0003008	system process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
5.17	6.60e-05	GO:0045202	synapse
4.87	3.40e-04	GO:0043005	neuron projection
5.47	6.85e-04	GO:0044456	synapse part
53.67	2.26e-03	GO:0061200	clathrin sculpted gamma-aminobutyric acid transport vesicle
53.67	2.26e-03	GO:0061202	clathrin sculpted gamma-aminobutyric acid transport vesicle membrane
4.61	8.06e-03	GO:0044433	cytoplasmic vesicle part
35.79	8.69e-03	GO:0060198	clathrin sculpted vesicle
5.00	1.02e-02	GO:0030659	cytoplasmic vesicle membrane
4.83	1.33e-02	GO:0012506	vesicle membrane
1.68	1.43e-02	GO:0005886	plasma membrane
1.66	2.04e-02	GO:0071944	cell periphery
5.90	2.36e-02	GO:0043025	neuronal cell body
5.73	2.83e-02	GO:0044297	cell body
5.70	2.93e-02	GO:0030424	axon
1.97	3.70e-02	GO:0044459	plasma membrane part
8.43	3.99e-02	GO:0030665	clathrin coated vesicle membrane
8.23	4.44e-02	GO:0008021	synaptic vesicle

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
20.45	7.04e-03	GO:0008066	glutamate receptor activity