ISMARA results: CEBPG

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Illumina Body Map 2: averaged replicates

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Results for CEBPG

Z-value: 3.08

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Transcription factors associated with CEBPG

Gene Symbol	Gene ID	Gene Info
CEBPG Ensembl NCBI GeneCards UniProt NextProt	ENSG00000153879.4	CCAAT enhancer binding protein gamma

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CEBPG	hg19_v2_chr19_+_33865218_33865254	-0.31	8.7e-02	Click!

Activity profile of CEBPG motif

Sorted Z-values of CEBPG motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_+_186435137 Show fit	28.67	ENST00000447445.1	KNG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	kininogen 1
chr3_+_186435065 Show fit	28.22	ENST00000287611.2 ENST00000265023.4	KNG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	kininogen 1
chr9_+_117085336 Show fit	17.28	ENST00000259396.8 ENST00000538816.1	ORM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	orosomucoid 1
chr9_+_117092149 Show fit	16.20	ENST00000431067.2 ENST00000412657.1	ORM2 Ensembl NCBI GeneCards UniProt NextProt Show fit	orosomucoid 2
chr4_+_74269956 Show fit	16.15	ENST00000295897.4 ENST00000415165.2 ENST00000503124.1 ENST00000509063.1 ENST00000401494.3	ALB Ensembl NCBI GeneCards UniProt NextProt Show fit	albumin
chr3_+_186330712 Show fit	13.38	ENST00000411641.2 ENST00000273784.5	AHSG Ensembl NCBI GeneCards UniProt NextProt Show fit	alpha-2-HS-glycoprotein
chr19_-_4540486 Show fit	12.49	ENST00000306390.6	LRG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine-rich alpha-2-glycoprotein 1
chr11_-_18258342 Show fit	11.60	ENST00000278222.4	SAA4 Ensembl NCBI GeneCards UniProt NextProt Show fit	serum amyloid A4, constitutive
chr11_+_18287801 Show fit	11.40	ENST00000532858.1 ENST00000405158.2	SAA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	serum amyloid A1
chr11_-_18270182 Show fit	11.26	ENST00000528349.1 ENST00000526900.1 ENST00000529528.1 ENST00000414546.2 ENST00000256733.4	SAA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	serum amyloid A2

Showing 1 to 10 of 182 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPG

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.6	74.7	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.7	52.1	GO:0006953	acute-phase response(GO:0006953)
2.8	33.5	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
1.2	21.8	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
5.3	21.0	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.5	18.6	GO:0006825	copper ion transport(GO:0006825)
3.4	17.0	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
5.4	16.2	GO:0044179	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
2.2	15.6	GO:0043606	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
1.2	13.0	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)

Showing 1 to 10 of 75 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.9	122.4	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	73.9	GO:0070062	extracellular exosome(GO:0070062)
1.1	54.6	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.2	48.8	GO:0072562	blood microparticle(GO:0072562)
0.3	33.0	GO:0035580	specific granule lumen(GO:0035580)
0.1	10.6	GO:0005796	Golgi lumen(GO:0005796)
0.0	10.1	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
3.9	7.8	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
1.8	7.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	6.9	GO:0005905	clathrin-coated pit(GO:0005905)

Showing 1 to 10 of 24 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	71.0	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.8	45.4	GO:0042056	chemoattractant activity(GO:0042056)
0.1	35.7	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.7	27.9	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	21.3	GO:0002020	protease binding(GO:0002020)
1.3	16.2	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.7	16.2	GO:0015643	toxic substance binding(GO:0015643)
5.2	15.6	GO:0004397	histidine ammonia-lyase activity(GO:0004397)
0.9	13.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.2	12.5	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)

Showing 1 to 10 of 54 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.9	58.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.5	22.5	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.3	20.7	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.2	16.2	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	16.2	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.2	13.4	PID BMP PATHWAY	BMP receptor signaling
0.4	12.8	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	11.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	10.6	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	4.6	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway

Showing 1 to 10 of 22 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.5	65.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
1.2	39.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
1.3	22.9	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.7	22.5	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.3	16.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	15.3	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.2	11.4	REACTOME DEFENSINS	Genes involved in Defensins
0.3	10.1	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3	7.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.5	7.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol

Showing 1 to 10 of 31 entries

Results for CEBPG

Z-value: 3.08

Motif logo

Transcription factors associated with CEBPG

Activity-expression correlation:

Activity profile of CEBPG motif

Sorted Z-values of CEBPG motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPG

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: