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Illumina Body Map 2: averaged replicates
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Results for HOXB13
Z-value: 0.58
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Transcription factors associated with HOXB13
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXB13 | hg19_v2_chr17_-_46806540_46806558 | 0.13 | 4.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_110993795 Show fit | 1.01 |
ENST00000271331.3
|
prokineticin 1 |
|
| chr1_-_151148492 Show fit | 0.85 |
ENST00000295314.4
|
tropomodulin 4 (muscle) |
|
| chr19_+_35634146 Show fit | 0.65 |
ENST00000586063.1
ENST00000270310.2 ENST00000588265.1 |
FXYD domain containing ion transport regulator 7 |
|
| chr6_-_139613269 Show fit | 0.58 |
ENST00000358430.3
|
taxilin beta |
|
| chr21_+_30672433 Show fit | 0.57 |
ENST00000451655.1
|
BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
|
| chr17_-_10560619 Show fit | 0.54 |
ENST00000583535.1
|
myosin, heavy chain 3, skeletal muscle, embryonic |
|
| chr8_+_77593448 Show fit | 0.54 |
ENST00000521891.2
|
zinc finger homeobox 4 |
|
| chr19_+_48497901 Show fit | 0.52 |
ENST00000339841.2
|
epididymal sperm binding protein 1 |
|
| chr16_-_80926457 Show fit | 0.49 |
ENST00000563626.1
ENST00000562231.1 |
RP11-314O13.1 |
|
| chr9_+_125133315 Show fit | 0.49 |
ENST00000223423.4
ENST00000362012.2 |
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXB13
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.5 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.2 | 1.2 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.1 | 1.2 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.0 | 1.0 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.1 | 0.8 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.1 | 0.5 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.0 | 0.5 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.1 | 0.4 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 0.1 | 0.4 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.0 | 0.4 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.8 | GO:0036379 | striated muscle thin filament(GO:0005865) myofilament(GO:0036379) |
| 0.0 | 0.5 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 0.5 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 0.4 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 0.4 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.4 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.0 | 0.2 | GO:1990393 | 3M complex(GO:1990393) |
| 0.0 | 0.2 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.0 | 0.2 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.2 | 1.2 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.1 | 1.0 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.8 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 0.5 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.0 | 0.5 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.5 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.1 | 0.4 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 0.0 | 0.4 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 0.4 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | PID IL3 PATHWAY | IL3-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 1.2 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.0 | 0.5 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.3 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 0.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.2 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.1 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |