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Illumina Body Map 2

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Results for RARA

Z-value: 0.86

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Transcription factors associated with RARA

Gene Symbol Gene ID Gene Info
ENSG00000131759.13 retinoic acid receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RARAhg19_v2_chr17_+_38497640_384976470.163.8e-01Click!

Activity profile of RARA motif

Sorted Z-values of RARA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_61777459 2.04 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIM domain containing 2
chr19_-_4540486 1.95 ENST00000306390.6
leucine-rich alpha-2-glycoprotein 1
chr3_+_126243126 1.84 ENST00000319340.2
carbohydrate (chondroitin 4) sulfotransferase 13
chr9_-_116840728 1.78 ENST00000265132.3
alpha-1-microglobulin/bikunin precursor
chr7_-_100239132 1.78 ENST00000223051.3
ENST00000431692.1
transferrin receptor 2
chr3_+_108855558 1.74 ENST00000467240.1
ENST00000477643.1
ENST00000479039.1
ENST00000593799.1
RP11-59E19.1
chr12_+_54378923 1.68 ENST00000303460.4
homeobox C10
chr4_-_48082192 1.65 ENST00000507351.1
TXK tyrosine kinase
chr17_-_61777090 1.57 ENST00000578061.1
LIM domain containing 2
chr10_-_52645416 1.55 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
APOBEC1 complementation factor
chr15_+_33010175 1.50 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
gremlin 1, DAN family BMP antagonist
chr11_+_45944190 1.44 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
glycosyltransferase-like 1B
chr3_-_112218378 1.37 ENST00000334529.5
B and T lymphocyte associated
chr22_+_45072925 1.36 ENST00000006251.7
proline rich 5 (renal)
chr1_+_145726886 1.36 ENST00000443667.1
PDZ domain containing 1
chr14_+_103573853 1.34 ENST00000560304.1
exocyst complex component 3-like 4
chr3_-_112218205 1.31 ENST00000383680.4
B and T lymphocyte associated
chr2_-_235405679 1.21 ENST00000390645.2
ADP-ribosylation factor-like 4C
chr1_+_6508100 1.18 ENST00000461727.1
espin
chr17_+_77704681 1.18 ENST00000328313.5
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr20_-_33865891 1.17 ENST00000540582.1
ER degradation enhancer, mannosidase alpha-like 2
chr16_+_56995762 1.17 ENST00000200676.3
ENST00000379780.2
cholesteryl ester transfer protein, plasma
chr10_-_135090360 1.16 ENST00000486609.1
ENST00000445355.3
ENST00000485491.2
ADAM metallopeptidase domain 8
chr10_-_135238076 1.15 ENST00000414069.2
shadow of prion protein homolog (zebrafish)
chr10_-_135090338 1.10 ENST00000415217.3
ADAM metallopeptidase domain 8
chr4_-_42154895 1.10 ENST00000502486.1
ENST00000504360.1
BEN domain containing 4
chr10_-_52645379 1.09 ENST00000395489.2
APOBEC1 complementation factor
chr16_-_11350036 1.07 ENST00000332029.2
suppressor of cytokine signaling 1
chr2_-_208031542 1.06 ENST00000423015.1
Kruppel-like factor 7 (ubiquitous)
chr17_-_8868991 1.03 ENST00000447110.1
phosphoinositide-3-kinase, regulatory subunit 5
chr6_+_36097992 1.03 ENST00000211287.4
mitogen-activated protein kinase 13
chr3_-_49726104 1.01 ENST00000383728.3
ENST00000545762.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr22_+_45072958 1.00 ENST00000403581.1
proline rich 5 (renal)
chr20_+_44519948 1.00 ENST00000354880.5
ENST00000191018.5
cathepsin A
chr1_-_156786634 0.99 ENST00000392306.2
ENST00000368199.3
SH2 domain containing 2A
chr12_+_54378849 0.98 ENST00000515593.1
homeobox C10
chr22_+_50624323 0.97 ENST00000380909.4
ENST00000303434.4
TraB domain containing
chr20_+_44520009 0.97 ENST00000607482.1
ENST00000372459.2
cathepsin A
chr1_-_156786530 0.96 ENST00000368198.3
SH2 domain containing 2A
chr19_+_55105085 0.95 ENST00000251372.3
ENST00000453777.1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chrX_+_48534985 0.93 ENST00000450772.1
Wiskott-Aldrich syndrome
chr17_+_14204389 0.92 ENST00000360954.2
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr19_-_7764281 0.92 ENST00000360067.4
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr22_+_23010756 0.91 ENST00000390304.2
immunoglobulin lambda variable 3-27
chr17_-_80291818 0.87 ENST00000269389.3
ENST00000581691.1
secreted and transmembrane 1
chr5_-_135290705 0.86 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr6_+_31540056 0.85 ENST00000418386.2
lymphotoxin alpha
chr14_+_103566481 0.84 ENST00000380069.3
exocyst complex component 3-like 4
chr20_-_44519839 0.83 ENST00000372518.4
neuralized E3 ubiquitin protein ligase 2
chr17_-_26926005 0.80 ENST00000536674.2
sperm associated antigen 5
chr7_-_81399438 0.80 ENST00000222390.5
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_148725544 0.79 ENST00000413966.1
protein disulfide isomerase family A, member 4
chr19_-_58864848 0.79 ENST00000263100.3
alpha-1-B glycoprotein
chr19_-_54784937 0.79 ENST00000434421.1
ENST00000314446.5
ENST00000391749.4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr2_+_192542879 0.78 ENST00000409510.1
nucleic acid binding protein 1
chr2_+_192543153 0.78 ENST00000425611.2
nucleic acid binding protein 1
chr11_-_65626753 0.78 ENST00000526975.1
ENST00000531413.1
cofilin 1 (non-muscle)
chr22_-_50970566 0.78 ENST00000405135.1
ENST00000401779.1
outer dense fiber of sperm tails 3B
chr19_-_19739007 0.76 ENST00000586703.1
ENST00000591042.1
ENST00000407877.3
lysophosphatidic acid receptor 2
chr11_-_65626797 0.76 ENST00000525451.2
cofilin 1 (non-muscle)
chr19_+_46144884 0.75 ENST00000593161.1
chromosome 19 open reading frame 83
chr22_-_50970506 0.73 ENST00000428989.2
ENST00000403326.1
outer dense fiber of sperm tails 3B
chr1_-_40367530 0.72 ENST00000372816.2
ENST00000372815.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr3_-_49726486 0.72 ENST00000449682.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr1_-_40367668 0.71 ENST00000397332.2
ENST00000429311.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr19_+_7733929 0.69 ENST00000221515.2
resistin
chr17_-_34308524 0.69 ENST00000293275.3
chemokine (C-C motif) ligand 16
chr19_-_58892389 0.69 ENST00000427624.2
ENST00000597582.1
zinc finger protein 837
chr14_+_103566665 0.69 ENST00000559116.1
exocyst complex component 3-like 4
chr5_-_134788086 0.69 ENST00000537858.1
TRAF-interacting protein with forkhead-associated domain, family member B
chr5_+_59783941 0.69 ENST00000506884.1
ENST00000504876.2
prostate androgen-regulated transcript 1 (non-protein coding)
chr4_-_77819002 0.69 ENST00000334306.2
sosondowah ankyrin repeat domain family member B
chr22_+_50312379 0.68 ENST00000407217.3
ENST00000403427.3
cysteine-rich with EGF-like domains 2
chr8_-_144815966 0.67 ENST00000388913.3
family with sequence similarity 83, member H
chr7_+_100136811 0.66 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr6_+_151358048 0.65 ENST00000450635.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr17_-_47287928 0.65 ENST00000507680.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr6_+_32709119 0.65 ENST00000374940.3
major histocompatibility complex, class II, DQ alpha 2
chr1_+_53098862 0.65 ENST00000517870.1
family with sequence similarity 159, member A
chr2_+_192542850 0.65 ENST00000410026.2
nucleic acid binding protein 1
chr17_-_62207485 0.64 ENST00000433197.3
endoplasmic reticulum to nucleus signaling 1
chr14_+_24641062 0.63 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8 meiotic recombination protein
chrY_+_2803322 0.63 ENST00000383052.1
ENST00000155093.3
ENST00000449237.1
ENST00000443793.1
zinc finger protein, Y-linked
chr1_+_171227069 0.63 ENST00000354841.4
flavin containing monooxygenase 1
chr19_-_19739321 0.63 ENST00000588461.1
lysophosphatidic acid receptor 2
chr1_+_26606608 0.62 ENST00000319041.6
SH3 domain binding glutamic acid-rich protein like 3
chr22_+_50312316 0.62 ENST00000328268.4
cysteine-rich with EGF-like domains 2
chr16_+_56995854 0.61 ENST00000566128.1
cholesteryl ester transfer protein, plasma
chr1_-_200379129 0.61 ENST00000367353.1
zinc finger protein 281
chr3_-_164914640 0.61 ENST00000241274.3
SLIT and NTRK-like family, member 3
chr9_-_72374848 0.61 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
protein prenyltransferase alpha subunit repeat containing 1
chr1_+_233463507 0.60 ENST00000366623.3
ENST00000366624.3
Mitogen-activated protein kinase kinase kinase MLK4
chr6_+_96025341 0.60 ENST00000369293.1
ENST00000358812.4
mannosidase, endo-alpha
chr3_+_186288454 0.59 ENST00000265028.3
DnaJ (Hsp40) homolog, subfamily B, member 11
chr7_-_81399678 0.59 ENST00000412881.1
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_-_204463829 0.59 ENST00000429009.1
ENST00000415899.1
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr19_+_7701985 0.58 ENST00000595950.1
ENST00000441779.2
ENST00000221283.5
ENST00000414284.2
syntaxin binding protein 2
chr1_+_25870070 0.58 ENST00000374338.4
low density lipoprotein receptor adaptor protein 1
chr2_-_208030886 0.57 ENST00000426163.1
Kruppel-like factor 7 (ubiquitous)
chr16_-_11680791 0.57 ENST00000571976.1
ENST00000413364.2
lipopolysaccharide-induced TNF factor
chr20_+_43538756 0.57 ENST00000537323.1
ENST00000217073.2
poly(A) binding protein, cytoplasmic 1-like
chr7_-_81399744 0.56 ENST00000421558.1
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_+_107599267 0.56 ENST00000361318.5
ENST00000370078.1
protein arginine methyltransferase 6
chr12_+_5541267 0.56 ENST00000423158.3
neurotrophin 3
chr19_-_4670345 0.56 ENST00000599630.1
ENST00000262947.3
chromosome 19 open reading frame 10
chr14_+_38065052 0.55 ENST00000556845.1
tetratricopeptide repeat domain 6
chr11_+_33037401 0.55 ENST00000241051.3
DEP domain containing 7
chr4_+_3578587 0.55 ENST00000514422.1
long intergenic non-protein coding RNA 955
chr19_+_49927006 0.54 ENST00000576655.1
golgi-associated, olfactory signaling regulator
chr19_+_12949251 0.54 ENST00000251472.4
microtubule associated serine/threonine kinase 1
chr9_+_6757634 0.53 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
lysine (K)-specific demethylase 4C
chr1_-_200379180 0.53 ENST00000294740.3
zinc finger protein 281
chr7_+_155090271 0.52 ENST00000476756.1
insulin induced gene 1
chr22_+_21996549 0.51 ENST00000248958.4
stromal cell-derived factor 2-like 1
chr22_-_19165917 0.51 ENST00000451283.1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr15_-_74495188 0.51 ENST00000563965.1
ENST00000395105.4
stimulated by retinoic acid 6
chr14_-_64194745 0.51 ENST00000247225.6
sphingosine-1-phosphate phosphatase 1
chr1_-_226187013 0.51 ENST00000272091.7
SDE2 telomere maintenance homolog (S. pombe)
chr19_-_49926698 0.50 ENST00000270631.1
parathyroid hormone 2
chr17_+_7476136 0.50 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
eukaryotic translation initiation factor 4A1
chr1_-_93426998 0.50 ENST00000370310.4
family with sequence similarity 69, member A
chr16_-_68014732 0.50 ENST00000268793.4
dipeptidase 3
chr16_+_69985083 0.49 ENST00000288040.6
ENST00000449317.2
C-type lectin domain family 18, member A
chr14_-_107078851 0.49 ENST00000390628.2
immunoglobulin heavy variable 1-58
chr11_-_58980342 0.49 ENST00000361050.3
macrophage expressed 1
chr1_+_160709055 0.48 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAM family member 7
chr12_+_125478241 0.48 ENST00000341446.8
BRI3 binding protein
chr20_+_43538692 0.48 ENST00000217074.4
ENST00000255136.3
poly(A) binding protein, cytoplasmic 1-like
chr16_+_577697 0.48 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
calpain 15
chr11_+_113848216 0.47 ENST00000299961.5
5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
chr7_-_81399411 0.47 ENST00000423064.2
hepatocyte growth factor (hepapoietin A; scatter factor)
chr20_+_3052264 0.46 ENST00000217386.2
oxytocin/neurophysin I prepropeptide
chr2_-_74730087 0.46 ENST00000341396.2
ladybird homeobox 2
chr9_+_114393634 0.46 ENST00000556107.1
ENST00000374294.3
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr2_+_85132749 0.46 ENST00000233143.4
thymosin beta 10
chr1_-_161039753 0.45 ENST00000368015.1
Rho GTPase activating protein 30
chr19_-_12405689 0.45 ENST00000355684.5
zinc finger protein 44
chr12_-_125348329 0.45 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
scavenger receptor class B, member 1
chr16_+_3115378 0.45 ENST00000529550.1
ENST00000551122.1
ENST00000525643.2
ENST00000548807.1
ENST00000528163.2
interleukin 32
chr16_-_11680759 0.45 ENST00000571459.1
ENST00000570798.1
ENST00000572255.1
ENST00000574763.1
ENST00000574703.1
ENST00000571277.1
ENST00000381810.3
lipopolysaccharide-induced TNF factor
chr19_+_16435625 0.45 ENST00000248071.5
ENST00000592003.1
Kruppel-like factor 2
chr16_+_29674277 0.44 ENST00000395389.2
sialophorin
chr22_-_29137771 0.44 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
checkpoint kinase 2
chr19_-_1174226 0.44 ENST00000587024.1
ENST00000361757.3
strawberry notch homolog 2 (Drosophila)
chr22_-_29138386 0.44 ENST00000544772.1
checkpoint kinase 2
chr10_+_102729249 0.44 ENST00000519649.1
ENST00000518124.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr11_+_74951948 0.43 ENST00000562197.2
trophoblast glycoprotein-like
chr17_-_77179487 0.41 ENST00000580508.1
RNA binding protein, fox-1 homolog (C. elegans) 3
chr16_+_8891670 0.41 ENST00000268261.4
ENST00000539622.1
ENST00000569958.1
ENST00000537352.1
phosphomannomutase 2
chr14_-_22103096 0.41 ENST00000542433.1
olfactory receptor, family 10, subfamily G, member 2
chr9_-_123691047 0.41 ENST00000373887.3
TNF receptor-associated factor 1
chr1_+_160051319 0.41 ENST00000368088.3
potassium inwardly-rectifying channel, subfamily J, member 9
chr1_-_16939976 0.40 ENST00000430580.2
neuroblastoma breakpoint family, member 1
chr1_+_91966656 0.40 ENST00000428239.1
ENST00000426137.1
cell division cycle 7
chr11_+_67033881 0.40 ENST00000308595.5
ENST00000526285.1
adrenergic, beta, receptor kinase 1
chr19_-_12992244 0.40 ENST00000538460.1
deoxyribonuclease II, lysosomal
chr1_+_200842083 0.40 ENST00000304244.2
G protein-coupled receptor 25
chr3_-_88108192 0.40 ENST00000309534.6
CGG triplet repeat binding protein 1
chr5_-_174871136 0.40 ENST00000393752.2
dopamine receptor D1
chr11_-_102323489 0.39 ENST00000361236.3
transmembrane protein 123
chr14_+_78227105 0.39 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
chromosome 14 open reading frame 178
chr5_-_43313574 0.39 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr2_-_113594279 0.39 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr2_+_219433281 0.39 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr1_+_91966384 0.39 ENST00000430031.2
ENST00000234626.6
cell division cycle 7
chr11_-_62997124 0.39 ENST00000306494.6
solute carrier family 22, member 25
chr5_+_118690466 0.38 ENST00000503646.1
tumor necrosis factor, alpha-induced protein 8
chr22_-_50689640 0.38 ENST00000448072.1
histone deacetylase 10
chr1_-_109203997 0.38 ENST00000370032.5
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr17_-_16557128 0.38 ENST00000423860.2
ENST00000311331.7
ENST00000583766.1
zinc finger protein 624
chr3_-_33138286 0.38 ENST00000416695.2
ENST00000342462.4
ENST00000399402.3
transmembrane protein with metallophosphoesterase domain
galactosidase, beta 1
chr6_+_139349817 0.38 ENST00000367660.3
ABRA C-terminal like
chr5_+_118691008 0.37 ENST00000504642.1
tumor necrosis factor, alpha-induced protein 8
chr17_-_47308100 0.37 ENST00000503902.1
ENST00000512250.1
phosphatase, orphan 1
chr1_-_161039647 0.37 ENST00000368013.3
Rho GTPase activating protein 30
chr19_-_12405606 0.37 ENST00000356109.5
zinc finger protein 44
chr17_+_42427826 0.37 ENST00000586443.1
granulin
chr17_-_61523535 0.36 ENST00000584031.1
ENST00000392976.1
cytochrome b561
chr1_+_2487078 0.36 ENST00000426449.1
ENST00000434817.1
ENST00000435221.2
tumor necrosis factor receptor superfamily, member 14
chr12_+_22778116 0.36 ENST00000538218.1
ethanolamine kinase 1
chr1_+_222988464 0.36 ENST00000420335.1
RP11-452F19.3
chr19_+_49956426 0.36 ENST00000293350.4
ENST00000540132.1
ENST00000455361.2
ENST00000433981.2
aldehyde dehydrogenase 16 family, member A1
chr1_-_109203648 0.36 ENST00000370031.1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr16_-_85969774 0.35 ENST00000598933.1
RP11-542M13.3
chr15_-_90777277 0.35 ENST00000328649.6
calcium and integrin binding 1 (calmyrin)
chr4_+_39408470 0.35 ENST00000257408.4
klotho beta
chr11_+_63137251 0.34 ENST00000310969.4
ENST00000279178.3
solute carrier family 22 (organic anion transporter), member 9
chr19_+_49458107 0.34 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BCL2-associated X protein
chr12_+_57916466 0.34 ENST00000355673.3
methyl-CpG binding domain protein 6
chr17_-_61523622 0.34 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
cytochrome b561
chr13_-_21918947 0.34 ENST00000423575.1
LINC00539
chr7_+_143078652 0.34 ENST00000354434.4
ENST00000449423.2
zyxin
chr1_+_2487631 0.34 ENST00000409119.1
tumor necrosis factor receptor superfamily, member 14
chr17_-_79479789 0.34 ENST00000571691.1
ENST00000571721.1
ENST00000573283.1
ENST00000575842.1
ENST00000575087.1
ENST00000570382.1
ENST00000331925.2
actin, gamma 1
chr9_+_140100113 0.34 ENST00000371521.4
ENST00000344894.5
ENST00000427047.2
ENST00000458322.2
NADPH dependent diflavin oxidoreductase 1
chr22_-_32058166 0.33 ENST00000435900.1
ENST00000336566.4
phosphatidylserine decarboxylase
chr22_-_21905750 0.33 ENST00000433039.1
RIMS binding protein 3C
chr3_-_101232019 0.33 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SUMO1/sentrin specific peptidase 7
chr12_+_104324112 0.33 ENST00000299767.5
heat shock protein 90kDa beta (Grp94), member 1
chr9_+_139780942 0.33 ENST00000247668.2
ENST00000359662.3
TNF receptor-associated factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of RARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:2000412 positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309) positive regulation of thymocyte migration(GO:2000412)
0.5 1.5 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.5 0.9 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.4 0.4 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3 1.8 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 0.9 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3 1.8 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.3 1.7 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 1.2 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.2 0.7 GO:2000870 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.2 2.0 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.2 1.5 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.2 2.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.6 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.2 0.6 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.2 0.6 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.2 2.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 1.4 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.5 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.2 2.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.2 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 0.5 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.1 0.4 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 2.9 GO:0051601 exocyst localization(GO:0051601)
0.1 0.7 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 0.5 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 1.9 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 0.3 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.1 0.7 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 1.8 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 2.4 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.4 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.6 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1 0.6 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 0.3 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 1.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 1.8 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.4 GO:0001807 regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.4 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.5 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 1.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.4 GO:0051413 response to cortisone(GO:0051413)
0.1 0.4 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.7 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.3 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 0.4 GO:0035106 operant conditioning(GO:0035106)
0.1 1.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.1 1.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.2 GO:0007493 endodermal cell fate determination(GO:0007493)
0.1 0.2 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.6 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.1 0.7 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.6 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.2 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 0.3 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.8 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.2 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.2 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 1.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.2 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.2 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 1.6 GO:0015879 carnitine transport(GO:0015879)
0.0 0.3 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.7 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 2.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.7 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.0 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 1.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 1.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.3 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.2 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.0 0.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.5 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.3 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.2 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 1.0 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.5 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 3.6 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.6 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.4 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.3 GO:0006260 DNA replication(GO:0006260)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 1.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.0 2.0 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.3 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.3 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 3.0 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.3 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.1 GO:1900451 positive regulation of glutamate receptor signaling pathway(GO:1900451)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:0061008 liver development(GO:0001889) hepaticobiliary system development(GO:0061008)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0045937 positive regulation of phosphorus metabolic process(GO:0010562) positive regulation of phosphate metabolic process(GO:0045937)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.0 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.6 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.7 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.3 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 1.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.5 GO:0007140 male meiosis(GO:0007140)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.8 2.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.3 2.0 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.3 2.2 GO:0070876 SOSS complex(GO:0070876)
0.3 1.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 2.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2 1.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 1.0 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.4 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 2.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 0.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 1.2 GO:0032426 stereocilium tip(GO:0032426)
0.1 3.0 GO:0000145 exocyst(GO:0000145)
0.1 0.3 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.6 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 1.8 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 2.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.0 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.7 GO:0042611 MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 2.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 3.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 1.3 GO:0005902 microvillus(GO:0005902)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0017129 triglyceride binding(GO:0017129)
0.4 1.8 GO:0019862 IgA binding(GO:0019862)
0.4 1.8 GO:0004998 transferrin receptor activity(GO:0004998)
0.3 1.8 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 0.6 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 0.6 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 0.7 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.2 1.4 GO:0005124 scavenger receptor binding(GO:0005124)
0.2 2.3 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.4 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.6 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.7 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.5 GO:0016015 morphogen activity(GO:0016015)
0.1 0.4 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.6 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 0.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.4 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.8 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.1 0.3 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.9 GO:0019863 IgE binding(GO:0019863)
0.1 0.6 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.3 GO:0038131 neuregulin receptor activity(GO:0038131)
0.1 0.5 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 1.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.3 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.9 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 1.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.2 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.2 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 3.1 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.6 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.0 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.5 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 1.0 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.3 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0005497 androgen binding(GO:0005497)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 2.6 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 2.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 3.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.5 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.7 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 2.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.1 ST ADRENERGIC Adrenergic Pathway
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 2.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 3.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.5 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 4.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 2.0 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 3.7 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification