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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: AAAGUGC

Z-value: 2.163

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_204380903	49.622	NM_032833	PPP1R15B	protein phosphatase 1, regulatory subunit 15B
chr18_+_21594349	49.615	NM_001135993 NM_001243425	TTC39C	tetratricopeptide repeat domain 39C
chr14_+_92790151	38.170	NM_153646	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr10_-_61469322	36.749	NM_194298	LOC100129721 SLC16A9	uncharacterized LOC100129721 solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr14_+_92789536	33.744	NM_153647	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr18_+_21572736	33.601	NM_153211	TTC39C	tetratricopeptide repeat domain 39C
chr11_-_113746205	31.267	NM_020886	USP28	ubiquitin specific peptidase 28
chr18_-_13726582	27.767	NM_001098801 NM_152352	FAM210A	family with sequence similarity 210, member A
chr14_+_92788924	26.548	NM_153648	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chrX_-_54384436	25.623	NM_001002838 NM_020922	WNK3	WNK lysine deficient protein kinase 3
chr8_+_26435339	23.881	NM_001386	DPYSL2	dihydropyrimidinase-like 2
chr2_+_10183630	23.851	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr2_+_203499819	22.221	NM_173511	FAM117B	family with sequence similarity 117, member B
chr19_-_49944613	21.537	NM_020309	SLC17A7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr12_-_16760935	21.043	NM_001001395 NM_001243609	LMO3	LIM domain only 3 (rhombotin-like 2)
chr13_+_113623496	20.890	NM_001112732	MCF2L	MCF.2 cell line derived transforming sequence-like
chr4_+_7045142	20.797	NM_152293	TADA2B	transcriptional adaptor 2B
chr10_-_120514669	20.150	NM_153810	C10orf46	chromosome 10 open reading frame 46
chr14_-_45431121	19.818	NM_017658	KLHL28	kelch-like 28 (Drosophila)
chr16_-_2264776	19.774	NM_001042371	PGP	phosphoglycolate phosphatase
chr7_+_108210188	19.165	NM_012328	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr17_+_36507708	18.674	NM_014598	SOCS7	suppressor of cytokine signaling 7
chr3_+_101443436	18.525	NM_024548	CEP97	centrosomal protein 97kDa
chr11_+_45868956	18.524	NM_021117	CRY2	cryptochrome 2 (photolyase-like)
chr17_-_28257017	18.367	NM_033389	SSH2	slingshot homolog 2 (Drosophila)
chr7_-_111846384	18.346	NM_014705	DOCK4	dedicator of cytokinesis 4
chr22_-_22089975	18.262	NM_013313	YPEL1	yippee-like 1 (Drosophila)
chr8_+_26371461	18.234	NM_001197293	DPYSL2	dihydropyrimidinase-like 2
chr20_-_4804067	17.817	NM_014737	RASSF2	Ras association (RalGDS/AF-6) domain family member 2
chr15_+_68871285	17.756	NM_006091	CORO2B	coronin, actin binding protein, 2B
chr6_+_107811272	17.647	NM_018013	SOBP	sine oculis binding protein homolog (Drosophila)
chr19_+_18208596	17.557	NM_015016	MAST3	microtubule associated serine/threonine kinase 3
chr6_-_152958533	17.186	NM_182961	SYNE1	spectrin repeat containing, nuclear envelope 1
chr12_-_16759531	16.971	NM_018640	LMO3	LIM domain only 3 (rhombotin-like 2)
chr15_+_68924326	16.803	NM_001190457	CORO2B	coronin, actin binding protein, 2B
chr16_+_85061303	16.685	NM_014732	KIAA0513	KIAA0513
chr11_+_45868668	16.649	NM_001127457	CRY2	cryptochrome 2 (photolyase-like)
chr16_-_2185824	16.509	NM_000296 NM_001009944	PKD1	polycystic kidney disease 1 (autosomal dominant)
chr1_+_145438437	16.118	NM_006472	TXNIP	thioredoxin interacting protein
chr15_+_68908878	15.564	NM_001190456	CORO2B	coronin, actin binding protein, 2B
chr3_-_15140652	15.329	NM_022340	ZFYVE20	zinc finger, FYVE domain containing 20
chr15_+_99645152	15.307	NM_015286 NM_145728	SYNM	synemin, intermediate filament protein
chr1_-_23857711	15.236	NM_004091	E2F2	E2F transcription factor 2
chr11_-_18655962	15.206	NM_194285	SPTY2D1	SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr3_-_13114547	15.202	NM_001134382	IQSEC1	IQ motif and Sec7 domain 1
chr2_-_222436996	15.076	NM_004438	EPHA4	EPH receptor A4
chr6_-_152957985	14.964	NM_033071	SYNE1	spectrin repeat containing, nuclear envelope 1
chr11_+_76156059	14.923	NM_020193	C11orf30	chromosome 11 open reading frame 30
chr3_+_169490852	14.832	NM_001185118 NM_018657	MYNN	myoneurin
chr3_-_57113292	14.793	NM_001128615	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr20_-_47894591	14.781	NM_021035	ZNFX1	zinc finger, NFX1-type containing 1
chr17_+_17942584	14.697	NM_024052	C17orf39	chromosome 17 open reading frame 39
chr13_-_26796343	14.612	NM_005977	RNF6	ring finger protein (C3H2C3 type) 6
chr12_+_32654976	14.596	NM_139241	FGD4	FYVE, RhoGEF and PH domain containing 4
chr5_-_134914968	14.452	NM_004887	CXCL14	chemokine (C-X-C motif) ligand 14
chr17_-_37764165	14.213	NM_006160	NEUROD2	neurogenic differentiation 2
chr2_-_73298815	14.203	NM_144579	SFXN5	sideroflexin 5
chr19_-_344778	14.160	NM_017550	MIER2	mesoderm induction early response 1, family member 2
chr2_+_25016174	13.944	NM_001199803 NM_024322	CENPO	centromere protein O
chr5_+_72921980	13.885	NM_001080479 NM_001177693	RGNEF	190 kDa guanine nucleotide exchange factor
chr17_-_66287256	13.778	NM_001174166 NM_004694	SLC16A6	solute carrier family 16, member 6 (monocarboxylic acid transporter 7)
chr2_+_74273449	13.750	NM_144993	TET3	tet methylcytosine dioxygenase 3
chr15_+_65134081	13.545	NM_001195059 NM_025201	PLEKHO2	pleckstrin homology domain containing, family O member 2
chr14_-_53620032	13.519	NM_001160147 NM_001160148 NM_030637	DDHD1	DDHD domain containing 1
chr6_-_167040700	13.480	NM_021135	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr9_+_99212379	13.399	NM_014282	HABP4	hyaluronan binding protein 4
chr20_-_4795768	13.303	NM_170774	RASSF2	Ras association (RalGDS/AF-6) domain family member 2
chr2_+_24163267	13.094	NM_181713	UBXN2A	UBX domain protein 2A
chr17_+_7184978	13.087	NM_001042	SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4
chr12_+_122064448	13.059	NM_032790	ORAI1	ORAI calcium release-activated calcium modulator 1
chr17_+_53342320	13.026	NM_002126	HLF	hepatic leukemia factor
chr17_+_29718641	12.793	NM_032932	RAB11FIP4	RAB11 family interacting protein 4 (class II)
chr7_-_44924946	12.784	NM_033224	PURB	purine-rich element binding protein B
chr12_-_42538432	12.760	NM_001099650 NM_173601	GXYLT1	glucoside xylosyltransferase 1
chr7_+_149535508	12.634	NM_001099220	ZNF862	zinc finger protein 862
chr4_+_53728481	12.576	NM_023940	RASL11B	RAS-like, family 11, member B
chr11_+_14665268	12.486	NM_000922	PDE3B	phosphodiesterase 3B, cGMP-inhibited
chr12_-_93323088	12.422	NM_003566	EEA1	early endosome antigen 1
chr9_+_82186846	12.412	NM_007005	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_+_57943843	12.366	NM_004984	KIF5A	kinesin family member 5A
chr19_+_50380681	12.267	NM_001168222 NM_024682	TBC1D17	TBC1 domain family, member 17
chrX_+_16737661	12.249	NM_032796	SYAP1	synapse associated protein 1
chr9_-_101470836	12.245	NM_005458	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
chr13_+_42846255	12.183	NM_016248	AKAP11	A kinase (PRKA) anchor protein 11
chr13_+_27131799	12.129	NM_006646	WASF3	WAS protein family, member 3
chr15_-_64648359	11.603	NM_022048	CSNK1G1	casein kinase 1, gamma 1
chr5_-_65017874	11.591	NM_019072	SGTB	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr12_+_72233486	11.583	NM_001146213 NM_001146214 NM_022771	TBC1D15	TBC1 domain family, member 15
chr6_+_139456240	11.394	NM_016217	HECA	headcase homolog (Drosophila)
chr11_-_1330891	11.391	NM_019009	TOLLIP	toll interacting protein
chr2_-_157189040	11.370	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2
chr1_+_3569098	11.366	NM_001204184 NM_001204185 NM_001204186 NM_001204187 NM_001204188 NM_005427	TP73	tumor protein p73
chr1_-_230513390	11.351	NM_024554	PGBD5	piggyBac transposable element derived 5
chr7_-_22396511	11.320	NM_012294	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr2_+_70142152	11.238	NM_001202513 NM_001202514 NM_002357	MXD1	MAX dimerization protein 1
chrX_+_133507299	11.161	NM_001015877 NM_032335 NM_032458	PHF6	PHD finger protein 6
chr11_+_121322848	11.152	NM_003105	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr4_+_6271558	11.066	NM_001145853 NM_006005	WFS1	Wolfram syndrome 1 (wolframin)
chr2_+_16080639	11.062	NM_005378	MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr1_+_6845381	11.040	NM_001195563 NM_001242701 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr16_+_19125243	11.004	NM_001034841	ITPRIPL2	inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr20_+_32951054	11.003	NM_031483	ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)
chr13_+_35516390	10.996	NM_015678	NBEA	neurobeachin
chr14_+_71108373	10.972	NM_015351	TTC9	tetratricopeptide repeat domain 9
chr17_+_8339135	10.954	NM_001025579 NM_030808	NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1
chr4_+_156588811	10.941	NM_001130684	GUCY1A3	guanylate cyclase 1, soluble, alpha 3
chr10_+_120789227	10.925	NM_199461	NANOS1	nanos homolog 1 (Drosophila)
chr3_-_53080038	10.916	NM_001005158 NM_016329	SFMBT1	Scm-like with four mbt domains 1
chr11_-_108093328	10.735	NM_002519	NPAT	nuclear protein, ataxia-telangiectasia locus
chr19_+_38397841	10.721	NM_015073	SIPA1L3	signal-induced proliferation-associated 1 like 3
chr3_-_13008959	10.720	NM_014869	IQSEC1	IQ motif and Sec7 domain 1
chr7_+_100136784	10.696	NM_006076	AGFG2	ArfGAP with FG repeats 2
chr5_-_174871162	10.671	NM_000794	DRD1	dopamine receptor D1
chr10_+_86088156	10.664	NM_018999	FAM190B	family with sequence similarity 190, member B
chr4_-_36245893	10.611	NM_015230	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr16_+_55512801	10.597	NM_004530	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr1_-_65431826	10.471	NM_002227	JAK1	Janus kinase 1
chr4_+_126237566	10.198	NM_024582	FAT4	FAT tumor suppressor homolog 4 (Drosophila)
chr4_+_72052354	10.187	NM_001098484 NM_001134742	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr5_-_39425297	10.176	NM_001244871 NM_001343	DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr7_-_99756275	10.130	NM_018275	C7orf43	chromosome 7 open reading frame 43
chr14_-_34419957	10.114	NM_022073	EGLN3	egl nine homolog 3 (C. elegans)
chr9_-_130742803	10.083	NM_001035254	FAM102A	family with sequence similarity 102, member A
chr3_-_170626425	10.027	NM_020390	EIF5A2	eukaryotic translation initiation factor 5A2
chr18_+_48556483	10.021	NM_005359	SMAD4	SMAD family member 4
chr1_+_19971865	10.012	NM_001204085	NBL1	neuroblastoma, suppression of tumorigenicity 1
chr1_-_47184730	10.000	NM_014774	KIAA0494	KIAA0494
chr1_+_183605207	9.893	NM_015149	RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr2_-_206950895	9.881	NM_017759	INO80D	INO80 complex subunit D
chr14_+_69865380	9.818	NM_001252148 NM_001252150 NM_018375	SLC39A9	solute carrier family 39 (zinc transporter), member 9
chr11_-_1593149	9.782	NM_004420	DUSP8	dual specificity phosphatase 8
chr11_-_46722115	9.760	NM_004308	ARHGAP1	Rho GTPase activating protein 1
chr15_+_91643429	9.758	NM_014848	SV2B	synaptic vesicle glycoprotein 2B
chr12_-_50297575	9.712	NM_012306	FAIM2	Fas apoptotic inhibitory molecule 2
chr13_-_26795927	9.704	NM_183043	RNF6	ring finger protein (C3H2C3 type) 6
chr2_-_68694389	9.633	NM_001024680	FBXO48	F-box protein 48
chr13_+_113656027	9.631	NM_024979	MCF2L	MCF.2 cell line derived transforming sequence-like
chr16_+_1664640	9.595	NM_020825	CRAMP1L	Crm, cramped-like (Drosophila)
chr4_+_55095263	9.495	NM_006206	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide
chr14_+_74111577	9.460	NM_001201366 NM_031427	DNAL1	dynein, axonemal, light chain 1
chr4_-_170947428	9.455	NM_021647	MFAP3L	microfibrillar-associated protein 3-like
chr16_+_53468344	9.444	NM_005611	RBL2	retinoblastoma-like 2 (p130)
chr15_+_85923739	9.431	NM_006738 NM_007200	AKAP13	A kinase (PRKA) anchor protein 13
chr7_-_4901437	9.428	NM_020144	PAPOLB	poly(A) polymerase beta (testis specific)
chr17_-_43568124	9.424	NM_014798	PLEKHM1	pleckstrin homology domain containing, family M (with RUN domain) member 1
chr3_-_129612371	9.388	NM_001128224	TMCC1	transmembrane and coiled-coil domain family 1
chr8_+_42752019	9.362	NM_032410	HOOK3	hook homolog 3 (Drosophila)
chr10_-_30348433	9.355	NM_020848	KIAA1462	KIAA1462
chr15_+_92937104	9.300	NM_006011	ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr7_-_14031049	9.257	NM_001163148	ETV1	ets variant 1
chr12_+_4382882	9.185	NM_001759	CCND2	cyclin D2
chrX_-_53310748	9.181	NM_001243197 NM_015075	IQSEC2	IQ motif and Sec7 domain 2
chr20_+_1875825	9.151	NM_001040023	SIRPA	signal-regulatory protein alpha
chr11_-_6494985	9.119	NM_001248007 NM_006458 NM_033278	TRIM3	tripartite motif containing 3
chr2_-_201936389	9.113	NM_173822	FAM126B	family with sequence similarity 126, member B
chr11_-_70507911	9.068	NM_133266	SHANK2	SH3 and multiple ankyrin repeat domains 2
chr3_-_15374082	9.009	NM_004844	SH3BP5	SH3-domain binding protein 5 (BTK-associated)
chr5_-_693413	8.894	NM_007030	TPPP	tubulin polymerization promoting protein
chr5_-_134871638	8.877	NM_006161	NEUROG1	neurogenin 1
chr1_+_160336856	8.841	NM_005598	NHLH1	nescient helix loop helix 1
chr17_+_4736612	8.807	NM_001024937 NM_015716 NM_153827 NM_170663	MINK1	misshapen-like kinase 1
chr14_-_73360792	8.770	NM_012074	DPF3	D4, zinc and double PHD fingers, family 3
chr11_-_74109417	8.763	NM_173582	PGM2L1	phosphoglucomutase 2-like 1
chr15_-_77712436	8.755	NM_024776	PEAK1	NKF3 kinase family member
chr5_-_171433876	8.751	NM_012300 NM_033644 NM_033645	FBXW11	F-box and WD repeat domain containing 11
chr12_-_110434187	8.712	NM_001135213 NM_001135214 NM_014776 NM_057169 NM_057170 NM_139201	GIT2	G protein-coupled receptor kinase interacting ArfGAP 2
chr3_-_56835829	8.653	NM_019555	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr4_-_56412968	8.650	NM_004898	CLOCK	clock homolog (mouse)
chr8_+_28747885	8.552	NM_001135726	HMBOX1	homeobox containing 1
chr17_-_40897025	8.481	NM_001991	EZH1	enhancer of zeste homolog 1 (Drosophila)
chr9_-_36400817	8.414	NM_194328 NM_194332	RNF38	ring finger protein 38
chr1_-_25573933	8.393	NM_020317	C1orf63	chromosome 1 open reading frame 63
chr6_-_136871956	8.369	NM_001198616 NM_001198617 NM_003980	MAP7	microtubule-associated protein 7
chr4_+_72204769	8.362	NM_003759	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr2_+_220042901	8.347	NM_024293	FAM134A	family with sequence similarity 134, member A
chr15_+_66994669	8.224	NM_005585	SMAD6	SMAD family member 6
chr5_+_140345746	8.192	NM_018899	PCDHAC2	protocadherin alpha subfamily C, 2
chr3_-_145968958	8.164	NM_001128306 NM_001177304 NM_020353	PLSCR4	phospholipid scramblase 4
chr2_-_197036301	8.161	NM_004226	STK17B	serine/threonine kinase 17b
chr9_-_130712866	8.158	NM_203305	FAM102A	family with sequence similarity 102, member A
chr7_+_86781869	8.102	NM_021145	DMTF1	cyclin D binding myb-like transcription factor 1
chr17_-_4890664	8.095	NM_001171167 NM_001171168	CAMTA2	calmodulin binding transcription activator 2
chr3_+_14989076	8.078	NM_003298	NR2C2	nuclear receptor subfamily 2, group C, member 2
chr13_-_29292961	8.065	NM_001135919 NM_181785	SLC46A3	solute carrier family 46, member 3
chr9_+_136397285	8.053	NM_001145320	ADAMTSL2	ADAMTS-like 2
chr1_-_23495347	8.038	NM_001142546 NM_033631	LUZP1	leucine zipper protein 1
chr2_-_240322620	7.984	NM_006037	HDAC4	histone deacetylase 4
chr4_-_44728518	7.956	NM_138335	GNPDA2	glucosamine-6-phosphate deaminase 2
chr13_+_39612440	7.927	NM_001012754 NM_001017370	NHLRC3	NHL repeat containing 3
chr19_+_14016955	7.923	NM_017721	CC2D1A	coiled-coil and C2 domain containing 1A
chr2_+_10184371	7.899	NM_001177718	KLF11	Kruppel-like factor 11
chr11_-_73309090	7.888	NM_015159	FAM168A	family with sequence similarity 168, member A
chr15_+_91643181	7.851	NM_001167580	SV2B	synaptic vesicle glycoprotein 2B
chr1_+_52608045	7.831	NM_004799 NM_007323 NM_007324	ZFYVE9	zinc finger, FYVE domain containing 9
chr1_+_19970207	7.721	NM_001204084	NBL1	neuroblastoma, suppression of tumorigenicity 1
chr7_-_100425035	7.686	NM_004444	EPHB4	EPH receptor B4
chr8_-_9009050	7.643	NM_001201329	PPP1R3B	protein phosphatase 1, regulatory subunit 3B
chr2_-_96811138	7.633	NM_004418	DUSP2	dual specificity phosphatase 2
chr3_-_149688638	7.609	NM_002628 NM_053024	PFN2	profilin 2
chr12_+_69864065	7.583	NM_001042555 NM_006654	FRS2	fibroblast growth factor receptor substrate 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.46	3.02e-13	GO:0009966	regulation of signal transduction
1.46	1.93e-12	GO:0050794	regulation of cellular process
2.36	4.49e-12	GO:0007399	nervous system development
2.27	5.11e-12	GO:0023051	regulation of signaling
1.86	4.21e-11	GO:0048731	system development
1.42	6.90e-11	GO:0050789	regulation of biological process
1.92	1.77e-10	GO:0048522	positive regulation of cellular process
1.70	1.83e-10	GO:0023052	signaling
1.38	2.91e-10	GO:0065007	biological regulation
2.07	4.53e-10	GO:0048583	regulation of response to stimulus
1.76	5.14e-10	GO:0048856	anatomical structure development
1.72	1.02e-09	GO:0007165	signal transduction
1.83	1.37e-09	GO:0048518	positive regulation of biological process
1.65	2.62e-09	GO:0032502	developmental process
1.68	9.15e-09	GO:0007275	multicellular organismal development
2.46	1.16e-08	GO:0006793	phosphorus metabolic process
2.46	1.16e-08	GO:0006796	phosphate metabolic process
2.21	1.42e-08	GO:0035556	intracellular signal transduction
2.71	3.64e-08	GO:0006468	protein phosphorylation
3.55	4.96e-08	GO:0051056	regulation of small GTPase mediated signal transduction
2.57	5.98e-08	GO:0016310	phosphorylation
2.80	1.01e-07	GO:0007167	enzyme linked receptor protein signaling pathway
1.63	1.27e-07	GO:0080090	regulation of primary metabolic process
1.62	1.91e-07	GO:0031323	regulation of cellular metabolic process
1.56	2.19e-07	GO:0051716	cellular response to stimulus
1.56	6.28e-07	GO:0019222	regulation of metabolic process
1.85	8.70e-07	GO:0030154	cell differentiation
1.69	3.75e-06	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.80	3.97e-06	GO:0048869	cellular developmental process
3.83	4.82e-06	GO:0046578	regulation of Ras protein signal transduction
1.86	6.36e-06	GO:0006464	protein modification process
2.63	6.87e-06	GO:0045893	positive regulation of transcription, DNA-dependent
2.54	9.86e-06	GO:0010628	positive regulation of gene expression
1.65	1.20e-05	GO:0051171	regulation of nitrogen compound metabolic process
2.38	1.87e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
2.40	1.87e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.20	2.00e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.03	2.22e-05	GO:0009893	positive regulation of metabolic process
2.31	2.72e-05	GO:0031328	positive regulation of cellular biosynthetic process
2.40	2.88e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
1.72	2.90e-05	GO:0051252	regulation of RNA metabolic process
1.73	3.01e-05	GO:0006355	regulation of transcription, DNA-dependent
1.19	3.19e-05	GO:0009987	cellular process
1.55	4.06e-05	GO:0060255	regulation of macromolecule metabolic process
1.78	4.13e-05	GO:0043412	macromolecule modification
2.25	4.64e-05	GO:0006351	transcription, DNA-dependent
2.27	4.81e-05	GO:0009891	positive regulation of biosynthetic process
1.65	5.72e-05	GO:0010468	regulation of gene expression
2.45	5.80e-05	GO:0051254	positive regulation of RNA metabolic process
2.03	6.52e-05	GO:0031325	positive regulation of cellular metabolic process
1.96	1.11e-04	GO:0051239	regulation of multicellular organismal process
1.65	1.29e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
3.03	1.40e-04	GO:0006917	induction of apoptosis
3.03	1.50e-04	GO:0012502	induction of programmed cell death
2.83	1.62e-04	GO:0007243	intracellular protein kinase cascade
2.83	1.62e-04	GO:0023014	signal transduction via phosphorylation event
2.16	1.66e-04	GO:0022008	neurogenesis
1.59	3.26e-04	GO:0031326	regulation of cellular biosynthetic process
1.61	5.01e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.96	5.86e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.57	5.89e-04	GO:0009889	regulation of biosynthetic process
2.55	6.01e-04	GO:0043068	positive regulation of programmed cell death
2.23	6.61e-04	GO:2000026	regulation of multicellular organismal development
2.53	6.67e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
2.59	8.33e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
2.50	9.06e-04	GO:0010942	positive regulation of cell death
2.03	1.30e-03	GO:0032774	RNA biosynthetic process
2.49	1.46e-03	GO:0043065	positive regulation of apoptosis
1.71	1.50e-03	GO:0007166	cell surface receptor linked signaling pathway
1.96	1.82e-03	GO:0010941	regulation of cell death
2.08	2.07e-03	GO:0048699	generation of neurons
2.04	2.16e-03	GO:0050793	regulation of developmental process
2.47	2.59e-03	GO:0000904	cell morphogenesis involved in differentiation
1.67	2.74e-03	GO:0048513	organ development
2.21	3.56e-03	GO:0042325	regulation of phosphorylation
2.20	4.19e-03	GO:0045595	regulation of cell differentiation
2.37	4.42e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.60	5.04e-03	GO:0048523	negative regulation of cellular process
1.92	5.22e-03	GO:0043067	regulation of programmed cell death
1.38	6.22e-03	GO:0044260	cellular macromolecule metabolic process
2.32	6.97e-03	GO:0051253	negative regulation of RNA metabolic process
2.15	7.32e-03	GO:0019220	regulation of phosphate metabolic process
2.15	7.32e-03	GO:0051174	regulation of phosphorus metabolic process
1.33	8.51e-03	GO:0032501	multicellular organismal process
1.90	8.62e-03	GO:0042981	regulation of apoptosis
2.57	1.02e-02	GO:0007264	small GTPase mediated signal transduction
1.72	1.12e-02	GO:0009653	anatomical structure morphogenesis
5.77	1.39e-02	GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.86	1.69e-02	GO:0010646	regulation of cell communication
2.98	1.71e-02	GO:0000165	MAPKKK cascade
2.09	1.79e-02	GO:0030182	neuron differentiation
2.65	1.91e-02	GO:0009894	regulation of catabolic process
5.02	1.96e-02	GO:0046777	protein autophosphorylation
2.17	2.30e-02	GO:0010629	negative regulation of gene expression
2.56	2.38e-02	GO:0007420	brain development
1.52	2.53e-02	GO:0048519	negative regulation of biological process
2.28	2.64e-02	GO:0007417	central nervous system development
2.40	2.70e-02	GO:0032583	regulation of gene-specific transcription
2.13	2.77e-02	GO:0001932	regulation of protein phosphorylation
3.48	2.83e-02	GO:0048511	rhythmic process
13.69	3.09e-02	GO:0043550	regulation of lipid kinase activity
1.87	3.34e-02	GO:0032879	regulation of localization
2.29	3.49e-02	GO:0043549	regulation of kinase activity
1.68	4.02e-02	GO:0065009	regulation of molecular function
12.64	4.90e-02	GO:0045022	early endosome to late endosome transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.36	2.07e-05	GO:0005634	nucleus
1.16	4.55e-05	GO:0005622	intracellular
1.16	1.46e-04	GO:0044424	intracellular part
1.53	3.98e-03	GO:0044459	plasma membrane part
1.71	4.69e-03	GO:0005654	nucleoplasm
1.70	9.51e-03	GO:0031226	intrinsic to plasma membrane
1.70	1.04e-02	GO:0005887	integral to plasma membrane
1.07	1.16e-02	GO:0044464	cell part
1.07	1.18e-02	GO:0005623	cell
1.53	2.38e-02	GO:0031981	nuclear lumen
4.32	2.60e-02	GO:0033267	axon part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.92	4.38e-09	GO:0005083	small GTPase regulator activity
1.20	6.27e-09	GO:0005488	binding
2.37	1.75e-08	GO:0001071	nucleic acid binding transcription factor activity
2.37	1.75e-08	GO:0003700	sequence-specific DNA binding transcription factor activity
2.62	3.04e-08	GO:0016773	phosphotransferase activity, alcohol group as acceptor
2.77	4.88e-08	GO:0004672	protein kinase activity
1.35	5.16e-08	GO:0005515	protein binding
2.96	4.00e-07	GO:0030695	GTPase regulator activity
2.44	4.25e-07	GO:0016301	kinase activity
2.88	8.68e-07	GO:0060589	nucleoside-triphosphatase regulator activity
4.55	1.26e-06	GO:0005085	guanyl-nucleotide exchange factor activity
2.90	2.96e-06	GO:0004674	protein serine/threonine kinase activity
5.59	3.38e-06	GO:0005057	receptor signaling protein activity
5.78	5.62e-06	GO:0005088	Ras guanyl-nucleotide exchange factor activity
13.84	1.57e-05	GO:0004709	MAP kinase kinase kinase activity
2.14	1.71e-05	GO:0030234	enzyme regulator activity
2.14	2.74e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
7.38	7.70e-05	GO:0004702	receptor signaling protein serine/threonine kinase activity
1.44	1.03e-04	GO:0046872	metal ion binding
2.00	1.55e-04	GO:0030528	transcription regulator activity
2.18	1.98e-04	GO:0019899	enzyme binding
1.43	2.13e-04	GO:0043169	cation binding
1.42	2.49e-04	GO:0043167	ion binding
5.40	7.63e-04	GO:0005089	Rho guanyl-nucleotide exchange factor activity
6.44	1.04e-03	GO:0003707	steroid hormone receptor activity
6.09	1.80e-03	GO:0004879	ligand-dependent nuclear receptor activity
6.57	2.79e-03	GO:0046332	SMAD binding
2.76	3.18e-03	GO:0008134	transcription factor binding
14.94	4.00e-03	GO:0070411	I-SMAD binding
1.51	6.28e-03	GO:0003677	DNA binding
4.58	1.04e-02	GO:0031625	ubiquitin protein ligase binding
4.46	1.33e-02	GO:0019199	transmembrane receptor protein kinase activity
1.99	1.50e-02	GO:0043565	sequence-specific DNA binding
2.52	2.04e-02	GO:0016564	transcription repressor activity
1.55	3.31e-02	GO:0016740	transferase activity
14.60	3.71e-02	GO:0051019	mitogen-activated protein kinase binding