Motif ID: AGCACCA

Z-value: 2.304


Mature miRNA associated with seed AGCACCA:

NamemiRBase Accession
hsa-miR-29a MIMAT0000086
hsa-miR-29b MIMAT0000100
hsa-miR-29c MIMAT0000681



Activity profile for motif AGCACCA.

activity profile for motif AGCACCA


Sorted Z-values histogram for motif AGCACCA

Sorted Z-values for motif AGCACCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCACCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_94023872 45.283 NM_000089
COL1A2
collagen, type I, alpha 2
chr2_+_189839078 41.032 NM_000090
COL3A1
collagen, type III, alpha 1
chr13_-_110959441 27.733 NM_001845
COL4A1
collagen, type IV, alpha 1
chr2_-_190044330 27.648 NM_000393
COL5A2
collagen, type V, alpha 2
chr3_-_120169493 25.937 NM_007085
FSTL1
follistatin-like 1
chr9_+_137533643 25.618 NM_000093
COL5A1
collagen, type V, alpha 1
chr5_-_151066492 25.323 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr16_+_55515468 24.098 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr2_-_238322840 23.937 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr15_-_48937795 22.419 NM_000138
FBN1
fibrillin 1
chr2_-_1748285 22.152 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr16_+_55512801 21.935 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr14_+_92790151 21.581 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr13_+_110959592 21.401 NM_001846
COL4A2
collagen, type IV, alpha 2
chr14_+_92788924 21.314 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_+_92789536 21.097 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr11_+_75273100 18.911 NM_001207014
NM_001235
SERPINH1

serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

chr5_-_121412805 16.590 NM_001178102
LOX
lysyl oxidase
chr1_-_204380903 15.883 NM_032833
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr17_-_48278987 15.603 NM_000088
COL1A1
collagen, type I, alpha 1
chr5_-_121414011 14.757 NM_002317
LOX
lysyl oxidase
chr15_+_74422742 14.708 NM_020851
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr15_+_74422589 14.558 NM_001130138
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_-_35325335 14.323 NM_001164825
NM_138428
C1orf212

chromosome 1 open reading frame 212

chr8_+_19796581 14.264 NM_000237
LPL
lipoprotein lipase
chr15_+_74421698 14.120 NM_001130136
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr15_+_74421986 14.038 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr9_+_101705710 13.597 NM_001855
COL15A1
collagen, type XV, alpha 1
chr5_-_149535420 13.445 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr12_-_10875848 13.373 NM_001145426
NM_003651
CSDA

cold shock domain protein A

chr17_-_15165873 13.021 NM_153321
PMP22
peripheral myelin protein 22
chr5_-_111312522 12.508 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr3_+_157154579 12.319 NM_002852
PTX3
pentraxin 3, long
chr1_+_24882565 12.202 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr5_-_111091947 12.090 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr17_-_40575117 11.804 NM_012232
PTRF
polymerase I and transcript release factor
chr1_-_236228476 11.757 NM_002508
NID1
nidogen 1
chr5_-_111093792 11.620 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr17_-_15168590 11.564 NM_000304
PMP22
peripheral myelin protein 22
chr17_-_15164043 11.480 NM_153322
PMP22
peripheral myelin protein 22
chr1_+_182992329 11.394 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr14_-_52535945 11.103 NM_007361
NID2
nidogen 2 (osteonidogen)
chr5_-_111093251 11.044 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr5_-_111093030 11.031 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr5_-_111092918 10.967 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr1_-_35324645 10.950 NM_001164824
C1orf212
chromosome 1 open reading frame 212
chr5_-_79286793 10.702 NM_001010891
NM_001167741
MTX3

metaxin 3

chr1_-_22263676 10.668 NM_005529
HSPG2
heparan sulfate proteoglycan 2
chr19_+_48216600 10.292 NM_014601
EHD2
EH-domain containing 2
chr9_-_110252045 9.629 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr1_-_17308072 9.017 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr1_-_202777545 8.776 NM_006618
KDM5B
lysine (K)-specific demethylase 5B
chr8_+_1772095 8.768 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr10_+_104503724 8.344 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr1_-_17307107 8.201 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr7_+_73442426 8.172 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr12_+_32654976 7.969 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr7_+_130126035 7.966 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr18_+_56530060 7.960 NM_018181
ZNF532
zinc finger protein 532
chr17_+_36507708 7.578 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr5_-_122372413 7.491 NM_000943
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr15_+_42867708 7.331 NM_020759
STARD9
StAR-related lipid transfer (START) domain containing 9
chr10_-_30024594 7.327 NM_003174
SVIL
supervillin
chr6_-_91006580 7.287 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr11_-_86666211 7.212 NM_012193
FZD4
frizzled family receptor 4
chr10_-_33247178 7.130 NM_002211
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr20_-_39317875 6.874 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr7_+_130131921 6.818 NM_002402
MEST
mesoderm specific transcript homolog (mouse)
chr7_+_12726910 6.806 NM_001195396
NM_005738
ARL4A

ADP-ribosylation factor-like 4A

chrX_-_51239426 6.708 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr1_+_53068042 6.707 NM_015696
GPX6
GPX7
glutathione peroxidase 6 (olfactory)
glutathione peroxidase 7
chr10_+_75757847 6.683 NM_003373
NM_014000
VCL

vinculin

chr5_-_95297597 6.677 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr1_-_225840660 6.653 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr6_+_138188352 6.556 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_-_32169619 6.545 NM_001856
COL16A1
collagen, type XVI, alpha 1
chr18_-_6414900 6.534 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr7_+_12726413 6.488 NM_001037164
NM_212460
ARL4A

ADP-ribosylation factor-like 4A

chr19_+_39897457 6.421 NM_003407
ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr11_-_102962903 6.414 NM_032299
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr6_-_91006460 6.400 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr7_+_130131172 6.285 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr7_+_116140097 6.255 NM_001206748
CAV2
caveolin 2
chr17_-_1532109 6.149 NM_152346
SLC43A2
solute carrier family 43, member 2
chr21_-_28339405 6.133 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr6_-_159065739 6.126 NM_006519
DYNLT1
dynein, light chain, Tctex-type 1
chr6_-_52441815 6.111 NM_012288
TRAM2
translocation associated membrane protein 2
chr9_-_113341772 6.084 NM_153366
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr4_-_157892545 6.044 NM_016205
PDGFC
platelet derived growth factor C
chr3_-_48632592 6.001 NM_000094
COL7A1
collagen, type VII, alpha 1
chr10_-_33246786 5.998 NM_133376
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr8_-_41754244 5.988 NM_001142446
ANK1
ankyrin 1, erythrocytic
chr14_-_45431121 5.715 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chr4_-_54930771 5.666 NM_012110
CHIC2
cysteine-rich hydrophobic domain 2
chr19_+_2328628 5.645 NM_001077238
NM_152988
SPPL2B

signal peptide peptidase-like 2B

chr10_-_29923900 5.555 NM_021738
SVIL
supervillin
chr1_-_150552127 5.544 NM_001197320
NM_021960
NM_182763
MCL1


myeloid cell leukemia sequence 1 (BCL2-related)


chrX_-_18372777 5.480 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr12_+_50898744 5.323 NM_173602
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr10_+_104535887 5.297 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr9_-_37465384 5.276 NM_014872
ZBTB5
zinc finger and BTB domain containing 5
chr7_+_116139619 5.220 NM_001206747
NM_001233
NM_198212
CAV2


caveolin 2


chr8_+_134203281 5.200 NM_001204869
NM_001204870
NM_003882
NM_080838
WISP1



WNT1 inducible signaling pathway protein 1



chr8_-_41522724 5.038 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr16_+_69220940 4.965 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr8_-_23261675 4.957 NM_002318
LOXL2
lysyl oxidase-like 2
chr1_-_68299047 4.955 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr17_+_40169592 4.883 NM_001001349
NKIRAS2
NFKB inhibitor interacting Ras-like 2
chr3_-_57678594 4.858 NM_152678
FAM116A
family with sequence similarity 116, member A
chr2_+_74273449 4.786 NM_144993
TET3
tet methylcytosine dioxygenase 3
chr1_+_40627031 4.755 NM_012421
RLF
rearranged L-myc fusion
chr7_+_135347211 4.738 NM_001130929
SLC13A4
C7orf73
solute carrier family 13 (sodium/sulfate symporters), member 4
chromosome 7 open reading frame 73
chr17_-_26941178 4.737 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr7_+_138916230 4.710 NM_173569
UBN2
ubinuclein 2
chr12_+_54332575 4.709 NM_017410
HOXC13
homeobox C13
chr11_-_18655962 4.643 NM_194285
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chrX_-_73834460 4.632 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr9_-_14398981 4.615 NM_001190738
NFIB
nuclear factor I/B
chr19_-_10121041 4.589 NM_015719
COL5A3
collagen, type V, alpha 3
chr12_-_102872329 4.584 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr3_-_79068542 4.576 NM_001145845
NM_133631
ROBO1

roundabout, axon guidance receptor, homolog 1 (Drosophila)

chr2_+_211342405 4.558 NM_001122633
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr1_+_26438267 4.558 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr19_+_46800296 4.522 NM_152795
HIF3A
hypoxia inducible factor 3, alpha subunit
chr4_+_124317884 4.473 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr21_+_47401644 4.438 NM_001848
COL6A1
collagen, type VI, alpha 1
chr6_-_111804413 4.409 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr8_-_41655139 4.330 NM_000037
NM_020475
NM_020476
NM_020477
ANK1



ankyrin 1, erythrocytic



chr4_-_52904424 4.317 NM_000232
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr14_-_90085325 4.312 NM_001085471
FOXN3
forkhead box N3
chr12_-_102874373 4.251 NM_000618
NM_001111283
NM_001111285
IGF1


insulin-like growth factor 1 (somatomedin C)


chr2_+_211421322 4.221 NM_001875
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chrX_+_107683015 4.206 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr12_+_13349601 4.199 NM_001423
EMP1
epithelial membrane protein 1
chr15_-_23932410 4.178 NM_002487
NDN
necdin homolog (mouse)
chr12_-_133464197 4.140 NM_001161344
NM_001161345
NM_001161346
NM_001161347
NM_018223
CHFR




checkpoint with forkhead and ring finger domains




chr17_-_37557851 4.139 NM_001184906
NM_032875
FBXL20

F-box and leucine-rich repeat protein 20

chr1_-_27816676 4.122 NM_001201404
NM_006990
WASF2

WAS protein family, member 2

chr9_-_14314036 4.107 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr14_-_76448091 4.066 NM_003239
TGFB3
transforming growth factor, beta 3
chr3_-_149470254 4.029 NM_016094
COMMD2
COMM domain containing 2
chr12_-_101603984 4.013 NM_145913
SLC5A8
solute carrier family 5 (iodide transporter), member 8
chr12_-_48398284 4.009 NM_001844
NM_033150
COL2A1

collagen, type II, alpha 1

chr15_+_81071708 4.006 NM_018689
KIAA1199
KIAA1199
chr3_-_79817058 3.996 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr19_-_44008984 3.920 NM_198850
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr3_+_158288952 3.913 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr14_-_89883306 3.894 NM_005197
FOXN3
forkhead box N3
chr14_+_74111577 3.839 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr21_+_47518012 3.806 NM_001849
NM_058174
NM_058175
COL6A2


collagen, type VI, alpha 2


chrX_+_73641084 3.788 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr11_-_119252364 3.778 NM_001243759
NM_004205
USP2

ubiquitin specific peptidase 2

chr6_-_56112315 3.739 NM_030820
COL21A1
collagen, type XXI, alpha 1
chrX_-_64254592 3.726 NM_001178032
NM_001243804
ZC4H2

zinc finger, C4H2 domain containing

chr1_-_113498615 3.724 NM_001166496
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr8_-_33424642 3.722 NM_024787
RNF122
ring finger protein 122
chr11_-_119234859 3.686 NM_171997
USP2
ubiquitin specific peptidase 2
chr5_-_118324223 3.679 NM_173666
DTWD2
DTW domain containing 2
chr8_-_57123858 3.635 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr5_-_132299263 3.634 NM_014423
AFF4
AF4/FMR2 family, member 4
chr22_-_39636906 3.615 NM_033016
PDGFB
platelet-derived growth factor beta polypeptide
chr7_-_92463211 3.606 NM_001259
CDK6
cyclin-dependent kinase 6
chr2_-_119605758 3.598 NM_001426
EN1
engrailed homeobox 1
chr12_+_8185241 3.592 NM_018416
FOXJ2
forkhead box J2
chr1_-_3528058 3.545 NM_001409
MEGF6
multiple EGF-like-domains 6
chr14_+_23067128 3.539 NM_022060
ABHD4
abhydrolase domain containing 4
chr7_-_92465929 3.530 NM_001145306
CDK6
cyclin-dependent kinase 6
chr1_-_31712733 3.528 NM_024522
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr15_-_33360084 3.517 NM_001103184
FMN1
formin 1
chr1_+_203595897 3.494 NM_001001396
NM_001684
ATP2B4

ATPase, Ca++ transporting, plasma membrane 4

chr10_-_128077072 3.467 NM_003474
NM_021641
ADAM12

ADAM metallopeptidase domain 12

chr16_+_66914380 3.439 NM_020786
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr3_+_101443436 3.422 NM_024548
CEP97
centrosomal protein 97kDa
chr1_-_146644045 3.422 NM_005399
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chrX_+_16804531 3.411 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr4_-_76944585 3.393 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr14_+_24836144 3.382 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr4_+_124320664 3.375 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr12_-_6451156 3.324 NM_001065
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr17_+_40172086 3.312 NM_001144927
NM_001144928
NM_001144929
NM_017595
NKIRAS2



NFKB inhibitor interacting Ras-like 2



chr3_-_120068077 3.302 NM_001099678
LRRC58
leucine rich repeat containing 58
chr5_-_139726173 3.296 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr2_+_211458078 3.245 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr14_+_24838301 3.210 NM_001198966
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chrX_-_112066353 3.184 NM_001113490
AMOT
angiomotin
chr9_+_112542496 3.155 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr7_-_115670828 3.154 NM_001018058
NM_012252
TFEC

transcription factor EC

chrX_+_49687212 3.136 NM_001127898
NM_001127899
CLCN5

chloride channel 5

chr8_-_93111915 3.111 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_50557019 3.108 NM_020717
SHROOM4
shroom family member 4
chr4_-_140005464 3.098 NM_006874
ELF2
E74-like factor 2 (ets domain transcription factor)
chr1_-_113498828 3.088 NM_003051
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr7_+_17338182 3.047 NM_001621
AHR
aryl hydrocarbon receptor
chr5_+_150827138 3.020 NM_078483
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr14_+_103058988 3.016 NM_015156
RCOR1
REST corepressor 1
chr8_-_93075190 3.005 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_30524485 2.964 NM_001077497
NM_025263
PRR3

proline rich 3

chr9_+_129567260 2.951 NM_001135776
NM_014007
ZBTB43

zinc finger and BTB domain containing 43

chr22_-_20004251 2.934 NM_001670
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr14_+_69865380 2.918 NM_001252148
NM_001252150
NM_018375
SLC39A9


solute carrier family 39 (zinc transporter), member 9



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.72 6.53e-12 GO:0032502 developmental process
1.75 4.03e-11 GO:0007275 multicellular organismal development
1.73 3.33e-09 GO:0048856 anatomical structure development
1.76 1.24e-08 GO:0048731 system development
14.30 1.56e-08 GO:0030199 collagen fibril organization
6.16 1.09e-06 GO:0030198 extracellular matrix organization
1.81 1.70e-05 GO:0048513 organ development
1.76 2.57e-05 GO:0030154 cell differentiation
1.90 4.47e-05 GO:0009653 anatomical structure morphogenesis
1.73 5.23e-05 GO:0048869 cellular developmental process
2.20 5.74e-05 GO:0050793 regulation of developmental process
1.39 5.92e-05 GO:0032501 multicellular organismal process
1.60 1.80e-04 GO:0031326 regulation of cellular biosynthetic process
1.59 1.82e-04 GO:0009889 regulation of biosynthetic process
2.28 1.96e-04 GO:2000026 regulation of multicellular organismal development
4.25 2.13e-04 GO:0043062 extracellular structure organization
2.12 5.64e-04 GO:0006351 transcription, DNA-dependent
2.08 1.68e-03 GO:0048699 generation of neurons
32.17 1.70e-03 GO:0032964 collagen biosynthetic process
2.04 1.82e-03 GO:0022008 neurogenesis
2.07 1.88e-03 GO:0009888 tissue development
1.77 2.34e-03 GO:0007399 nervous system development
1.58 2.39e-03 GO:0048519 negative regulation of biological process
9.19 2.78e-03 GO:0043588 skin development
1.24 2.92e-03 GO:0065007 biological regulation
2.24 3.80e-03 GO:0030030 cell projection organization
2.46 3.85e-03 GO:0072358 cardiovascular system development
2.46 3.85e-03 GO:0072359 circulatory system development
10.72 4.00e-03 GO:0045646 regulation of erythrocyte differentiation
2.03 4.14e-03 GO:0040011 locomotion
1.55 4.70e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.45 4.88e-03 GO:0016043 cellular component organization
1.98 7.07e-03 GO:0009611 response to wounding
2.15 7.20e-03 GO:0045595 regulation of cell differentiation
1.54 7.40e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.57 7.50e-03 GO:0042221 response to chemical stimulus
2.07 8.68e-03 GO:0007155 cell adhesion
2.07 8.68e-03 GO:0022610 biological adhesion
2.44 9.66e-03 GO:0051094 positive regulation of developmental process
2.23 1.01e-02 GO:0042060 wound healing
1.94 1.13e-02 GO:0048468 cell development
1.91 1.19e-02 GO:0032774 RNA biosynthetic process
1.57 1.27e-02 GO:0048523 negative regulation of cellular process
2.23 1.27e-02 GO:0048666 neuron development
6.58 1.28e-02 GO:0060041 retina development in camera-type eye
1.24 1.31e-02 GO:0050789 regulation of biological process
1.41 1.34e-02 GO:0031323 regulation of cellular metabolic process
2.14 1.45e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.24 1.53e-02 GO:0006928 cellular component movement
2.46 1.70e-02 GO:0016477 cell migration
1.38 1.73e-02 GO:0019222 regulation of metabolic process
1.49 1.83e-02 GO:0071842 cellular component organization at cellular level
2.76 2.24e-02 GO:0001944 vasculature development
1.40 2.63e-02 GO:0080090 regulation of primary metabolic process
1.48 2.65e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 2.69e-02 GO:0071840 cellular component organization or biogenesis
1.87 2.82e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.41 2.95e-02 GO:0060255 regulation of macromolecule metabolic process
2.05 2.98e-02 GO:0030182 neuron differentiation
1.49 3.01e-02 GO:0010468 regulation of gene expression
2.93 3.58e-02 GO:0030168 platelet activation
1.14 3.66e-02 GO:0009987 cellular process
1.86 3.79e-02 GO:0042127 regulation of cell proliferation
1.24 3.94e-02 GO:0050794 regulation of cellular process
1.53 4.12e-02 GO:0065008 regulation of biological quality
2.04 4.20e-02 GO:0031327 negative regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
16.98 2.55e-17 GO:0005581 collagen
7.69 2.18e-14 GO:0044420 extracellular matrix part
4.31 7.92e-13 GO:0005578 proteinaceous extracellular matrix
3.92 2.44e-12 GO:0031012 extracellular matrix
23.40 3.48e-08 GO:0005583 fibrillar collagen
6.89 8.53e-07 GO:0005604 basement membrane
2.03 3.42e-05 GO:0044421 extracellular region part
4.98 5.11e-04 GO:0030027 lamellipodium
21.45 3.58e-03 GO:0005587 collagen type IV
8.04 4.97e-03 GO:0001725 stress fiber
32.17 8.07e-03 GO:0005588 collagen type V
7.51 8.10e-03 GO:0032432 actin filament bundle
18.38 8.14e-03 GO:0030935 sheet-forming collagen
3.06 1.26e-02 GO:0031252 cell leading edge
6.82 1.57e-02 GO:0042641 actomyosin
1.48 1.63e-02 GO:0044459 plasma membrane part
5.15 3.87e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
12.87 4.53e-02 GO:0030934 anchoring collagen

Gene overrepresentation in function category:

enrichment   p-value GO term description
26.32 4.72e-10 GO:0048407 platelet-derived growth factor binding
7.64 1.23e-09 GO:0005201 extracellular matrix structural constituent
1.29 1.08e-05 GO:0005515 protein binding
2.08 2.39e-05 GO:0001071 nucleic acid binding transcription factor activity
2.08 2.39e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.15 7.34e-05 GO:0005488 binding
4.21 2.06e-03 GO:0019838 growth factor binding
3.55 4.23e-03 GO:0003714 transcription corepressor activity
4.10 5.88e-03 GO:0004222 metalloendopeptidase activity
1.79 1.09e-02 GO:0030528 transcription regulator activity
1.46 2.22e-02 GO:0003677 DNA binding