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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 2.487

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_151151514	34.815		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151151516	29.043		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151151462	27.757	NM_005754 NM_198395	G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151151511	25.340		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr21_-_40720938	22.053		HMGN1	high mobility group nucleosome binding domain 1
chr6_-_86352650	20.457		SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr19_+_17666457	19.256		GLT25D1	glycosyltransferase 25 domain containing 1
chr15_-_69113213	18.968		ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr15_-_69113089	18.244		ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr6_-_86352656	18.229		SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr20_-_33872505	18.170	NM_181468	EIF6	eukaryotic translation initiation factor 6
chr12_-_46662533	18.100		SLC38A1	solute carrier family 38, member 1
chr20_-_33872289	17.102		EIF6	eukaryotic translation initiation factor 6
chr3_+_52719935	16.852	NM_014366 NM_206825 NM_206826	GNL3	guanine nucleotide binding protein-like 3 (nucleolar)
chr5_+_170814707	16.796	NM_001037738 NM_002520 NM_199185	NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr4_-_103748649	15.875	NM_181887 NM_181891	UBE2D3	ubiquitin-conjugating enzyme E2D 3
chr6_-_86352635	15.863	NM_001159673	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_+_64798050	15.847	NM_007235	XPOT	exportin, tRNA (nuclear export receptor for tRNAs)
chr6_-_86352982	15.744	NM_001159677 NM_006372	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr6_-_86352564	15.714	NM_001159674 NM_001253771	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr3_-_184870727	15.615	NM_001025266	C3orf70	chromosome 3 open reading frame 70
chr12_-_27091207	15.586	NM_018164	ASUN	asunder, spermatogenesis regulator homolog (Drosphila)
chr5_-_133340358	15.543		VDAC1	voltage-dependent anion channel 1
chr12_-_31479038	14.794		FAM60A	family with sequence similarity 60, member A
chr5_+_170814952	14.725		NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr6_-_86352696	14.634		SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr5_+_151151483	14.564		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr5_-_133340380	14.499		VDAC1	voltage-dependent anion channel 1
chr4_-_103748254	14.434	NM_181892	UBE2D3	ubiquitin-conjugating enzyme E2D 3
chr7_+_75931991	14.270		HSPB1	heat shock 27kDa protein 1
chr9_-_113018711	14.222		TXN	thioredoxin
chr6_+_34204647	14.207	NM_145901 NM_145902	HMGA1	high mobility group AT-hook 1
chr19_+_797448	14.184		PTBP1	polypyrimidine tract binding protein 1
chr9_-_113018802	14.172		TXN	thioredoxin
chr4_-_103748966	14.047	NM_003340 NM_181886 NM_181888 NM_181889	UBE2D3	ubiquitin-conjugating enzyme E2D 3
chr12_-_31479120	14.034	NM_001135811 NM_021238 NM_001135812	FAM60A	family with sequence similarity 60, member A
chr12_-_27090877	14.020		ASUN	asunder, spermatogenesis regulator homolog (Drosphila)
chr7_+_75931829	13.967	NM_001540	HSPB1	heat shock 27kDa protein 1
chr19_+_17666502	13.846	NM_024656	GLT25D1	glycosyltransferase 25 domain containing 1
chr12_-_31479084	13.725		FAM60A	family with sequence similarity 60, member A
chr3_+_184081178	13.634	NM_006232	POLR2H	polymerase (RNA) II (DNA directed) polypeptide H
chr5_-_133340427	13.486		VDAC1	voltage-dependent anion channel 1
chr5_-_133340389	13.435		VDAC1	voltage-dependent anion channel 1
chr15_-_69113255	12.998	NM_006305	ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr7_+_16685757	12.959	NM_001159767 NM_014038	BZW2	basic leucine zipper and W2 domains 2
chr2_-_198364997	12.878	NM_199440	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr21_-_40721010	12.776	NM_004965	HMGN1	high mobility group nucleosome binding domain 1
chr4_-_120987890	12.420	NM_002358	MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)
chr9_-_113018869	12.408	NM_001244938 NM_003329	TXN	thioredoxin
chr18_+_55019720	12.294	NM_015879	ST8SIA3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chrX_-_20284708	12.243	NM_004586	RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr17_-_4851797	12.237	NM_005022	PFN1	profilin 1
chr22_+_20105145	12.223		RANBP1	RAN binding protein 1
chr17_-_40075153	11.944		ACLY	ATP citrate lyase
chr19_-_2456954	11.554	NM_032737	LMNB2	lamin B2
chr3_+_40498781	11.515	NM_003973 NM_001034996	RPL14	ribosomal protein L14
chr17_-_4851827	11.318		PFN1	profilin 1
chr17_-_56084611	11.247		SRSF1	serine/arginine-rich splicing factor 1
chr20_-_1373702	11.147		FKBP1A-SDCBP2 FKBP1A	FKBP1A-SDCBP2 readthrough (non-protein coding) FK506 binding protein 1A, 12kDa
chr22_+_20105076	11.060		RANBP1	RAN binding protein 1
chr3_+_151986731	11.021		MBNL1	muscleblind-like (Drosophila)
chr17_-_40075238	10.785	NM_001096 NM_198830	ACLY	ATP citrate lyase
chr20_-_33872571	10.679	NM_002212 NM_181466	EIF6	eukaryotic translation initiation factor 6
chr4_-_129208967	10.673		PGRMC2	progesterone receptor membrane component 2
chr1_+_162531349	10.651		UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1
chr1_+_182992329	10.506	NM_002293	LAMC1	laminin, gamma 1 (formerly LAMB2)
chr2_+_198365012	10.410		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr7_-_105925410	10.359	NM_005746	NAMPT	nicotinamide phosphoribosyltransferase
chr1_+_86046434	10.350	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr2_-_69614321	10.198	NM_001244710 NM_002056	GFPT1	glutamine--fructose-6-phosphate transaminase 1
chr3_-_49066760	10.156		IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr22_+_20105095	10.105		RANBP1	RAN binding protein 1
chr12_+_104359557	10.002	NM_003211	TDG	thymine-DNA glycosylase
chr4_-_129208928	9.937		PGRMC2	progesterone receptor membrane component 2
chr19_-_2427530	9.932		TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr3_-_49066858	9.908	NM_000884	IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2
chrX_-_109561298	9.775		AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr19_+_797452	9.717		PTBP1	polypyrimidine tract binding protein 1
chr20_-_1373744	9.688	NM_000801 NM_001199786 NM_054014	FKBP1A	FK506 binding protein 1A, 12kDa
chr7_+_139044997	9.642		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr8_+_126010748	9.630		SQLE	squalene epoxidase
chr6_+_34204576	9.535	NM_002131 NM_145899 NM_145903	HMGA1	high mobility group AT-hook 1
chr17_-_40075190	9.439		ACLY	ATP citrate lyase
chr17_-_62658311	9.413	NM_022739	SMURF2	SMAD specific E3 ubiquitin protein ligase 2
chrX_-_109561314	9.390	NM_001025580 NM_015365	AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_+_1447495	9.298	NM_001170535 NM_018188	ATAD3A	ATPase family, AAA domain containing 3A
chr3_-_49066813	9.257		IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr12_+_108079516	9.176	NM_007062	PWP1	PWP1 homolog (S. cerevisiae)
chr2_+_198365113	8.942		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr6_+_34204663	8.919		HMGA1	high mobility group AT-hook 1
chr12_+_69004614	8.878	NM_001010942 NM_001251917 NM_001251918 NM_001251921 NM_001251922 NM_015646	RAP1B	RAP1B, member of RAS oncogene family
chr18_-_51750934	8.874		MBD2	methyl-CpG binding domain protein 2
chr17_-_40075229	8.842		ACLY	ATP citrate lyase
chr12_+_69004710	8.838		RAP1B	RAP1B, member of RAS oncogene family
chr5_-_133340823	8.795	NM_003374	VDAC1	voltage-dependent anion channel 1
chr1_-_150208134	8.792		ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr2_+_29117503	8.723	NM_015131	WDR43	WD repeat domain 43
chrX_-_153599581	8.680		FLNA	filamin A, alpha
chr1_+_154947166	8.666		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr8_+_126442557	8.646	NM_025195	TRIB1	tribbles homolog 1 (Drosophila)
chr19_+_797390	8.618	NM_002819 NM_031990 NM_031991 NM_175847	PTBP1	polypyrimidine tract binding protein 1
chr1_+_1447871	8.614	NM_001170536	ATAD3A	ATPase family, AAA domain containing 3A
chr12_+_69004684	8.570		RAP1B	RAP1B, member of RAS oncogene family
chr11_-_76091866	8.552	NM_004705	PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr10_+_17271276	8.551		VIM	vimentin
chr1_-_6259616	8.516	NM_000983	RPL22	ribosomal protein L22
chr6_-_28891409	8.485		TRIM27	tripartite motif containing 27
chr1_+_154947147	8.483		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr2_+_201171411	8.460		SPATS2L	spermatogenesis associated, serine-rich 2-like
chr5_+_68462985	8.444		CCNB1	cyclin B1
chr7_-_45960738	8.380	NM_000598 NM_001013398	IGFBP3	insulin-like growth factor binding protein 3
chr7_+_73097897	8.350	NM_001202560 NM_017528	WBSCR22	Williams Beuren syndrome chromosome region 22
chr8_+_126010719	8.341	NM_003129	SQLE	squalene epoxidase
chr8_+_110346549	8.321	NM_001193557 NM_020189	ENY2	enhancer of yellow 2 homolog (Drosophila)
chr5_+_68462836	8.313	NM_031966	CCNB1	cyclin B1
chr1_+_112162397	8.291	NM_001010935 NM_002884	RAP1A	RAP1A, member of RAS oncogene family
chr7_-_132766697	8.284	NM_017812	CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3
chr5_+_68462948	8.263		CCNB1	cyclin B1
chr14_-_69445948	8.220		ACTN1	actinin, alpha 1
chr16_-_66864864	8.210	NM_001018159 NM_001018160 NM_003905	NAE1	NEDD8 activating enzyme E1 subunit 1
chr4_+_57301898	8.178	NM_006452	PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr7_+_73097930	8.170		WBSCR22	Williams Beuren syndrome chromosome region 22
chr1_+_43148359	8.142		YBX1	Y box binding protein 1
chr17_-_56084514	8.111		SRSF1	serine/arginine-rich splicing factor 1
chr14_-_69445989	8.097		ACTN1	actinin, alpha 1
chr15_+_52311432	8.090		MAPK6	mitogen-activated protein kinase 6
chr19_+_3572958	8.038		HMG20B	high mobility group 20B
chr10_+_17271341	8.003		VIM	vimentin
chr5_+_132387775	8.000		HSPA4	heat shock 70kDa protein 4
chr1_+_54412007	7.988	NM_052940	LRRC42	leucine rich repeat containing 42
chr14_-_69446038	7.966	NM_001102 NM_001130004 NM_001130005	ACTN1	actinin, alpha 1
chr8_+_97274106	7.928		PTDSS1	phosphatidylserine synthase 1
chr14_-_69446008	7.892		ACTN1	actinin, alpha 1
chr11_-_2950593	7.889	NM_003311	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr12_-_9102262	7.888	NM_001207024 NM_002355	M6PR	mannose-6-phosphate receptor (cation dependent)
chr16_-_66864803	7.871		NAE1	NEDD8 activating enzyme E1 subunit 1
chr14_-_69445978	7.868		ACTN1	actinin, alpha 1
chr12_-_54069856	7.834		ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr5_+_52095929	7.797		PELO	pelota homolog (Drosophila)
chr8_+_37887990	7.742	NM_004095	EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1
chr10_+_17271302	7.693		VIM	vimentin
chrX_+_19362010	7.628	NM_000284 NM_001173454 NM_001173455 NM_001173456	PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1
chr3_-_156877882	7.626		CCNL1	cyclin L1
chr10_+_17271277	7.619		VIM	vimentin
chr19_+_3572950	7.616		HMG20B	high mobility group 20B
chr9_+_131452253	7.615	NM_001248001	SET	SET nuclear oncogene
chr7_-_148581403	7.596	NM_001203247 NM_001203248 NM_004456 NM_152998	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr14_-_69445974	7.589		ACTN1	actinin, alpha 1
chr5_+_132387699	7.578		HSPA4	heat shock 70kDa protein 4
chr10_-_13390018	7.540		SEPHS1	selenophosphate synthetase 1
chr7_-_105925329	7.503		NAMPT	nicotinamide phosphoribosyltransferase
chr7_-_148581377	7.500		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr1_-_150208462	7.492	NM_001136478 NM_030920	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_54304107	7.475	NM_001168551 NM_018087	TMEM48	transmembrane protein 48
chr5_+_132387734	7.375		HSPA4	heat shock 70kDa protein 4
chr7_+_2394525	7.362		EIF3B	eukaryotic translation initiation factor 3, subunit B
chr1_+_154947116	7.356	NM_001826	CKS1B	CDC28 protein kinase regulatory subunit 1B
chr17_-_56084590	7.328		SRSF1	serine/arginine-rich splicing factor 1
chr7_+_128379345	7.315	NM_001130674 NM_001199671 NM_001199672 NM_001199673 NM_001199674 NM_001219	CALU	calumenin
chr7_+_139044696	7.307		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr20_-_10654139	7.288		JAG1	jagged 1
chr7_-_132766834	7.264		CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3
chr1_+_155658881	7.245	NM_001199849 NM_001199850 NM_001199851 NM_004632 NM_033657	DAP3	death associated protein 3
chr19_-_8373157	7.237	NM_001165895 NM_016579	CD320	CD320 molecule
chr20_+_56964289	7.234		VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr5_+_132387579	7.231	NM_002154	HSPA4	heat shock 70kDa protein 4
chr12_-_58146108	7.211		CDK4	cyclin-dependent kinase 4
chr4_-_24586176	7.210		DHX15	DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr7_+_128379428	7.143		CALU	calumenin
chr1_+_165797060	7.106		UCK2	uridine-cytidine kinase 2
chr12_+_104324157	7.092		HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr2_-_33824294	7.085	NM_015475	FAM98A	family with sequence similarity 98, member A
chr7_+_128379452	7.083		CALU	calumenin
chr17_+_73201528	7.080	NM_024844	NUP85	nucleoporin 85kDa
chr1_-_33282844	7.068		YARS	tyrosyl-tRNA synthetase
chr21_-_30445949	7.017		CCT8	chaperonin containing TCP1, subunit 8 (theta)
chr7_+_139044701	7.013		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr21_-_30445913	6.996		CCT8	chaperonin containing TCP1, subunit 8 (theta)
chr12_-_58146025	6.987		CDK4	cyclin-dependent kinase 4
chr1_+_162531229	6.982	NM_003115	UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1
chr9_-_15510899	6.981	NM_001128217 NM_033222	PSIP1	PC4 and SFRS1 interacting protein 1
chr4_+_146019368	6.980		ABCE1	ATP-binding cassette, sub-family E (OABP), member 1
chr5_+_33440801	6.963	NM_152295	TARS	threonyl-tRNA synthetase
chr7_-_148581379	6.956		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr12_-_54070108	6.936	NM_005176	ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr6_-_10412606	6.928	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_+_165796652	6.926	NM_012474	UCK2	uridine-cytidine kinase 2
chr6_+_34204928	6.925		HMGA1	high mobility group AT-hook 1
chr17_-_48474910	6.922	NM_018509	LRRC59	leucine rich repeat containing 59
chr12_+_104324192	6.917		HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr7_+_128379400	6.914		CALU	calumenin
chrX_+_153991106	6.893		DKC1	dyskeratosis congenita 1, dyskerin
chr12_-_58146110	6.892		CDK4	cyclin-dependent kinase 4
chr12_-_46662779	6.866		SLC38A1	solute carrier family 38, member 1
chr7_-_148581359	6.844		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr19_+_58898634	6.839	NM_001009	RPS5	ribosomal protein S5
chr7_+_117824085	6.824	NM_016200	NAA38	N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr20_+_56964162	6.799	NM_001195677 NM_004738	VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr10_+_75936546	6.792		ADK	adenosine kinase
chr12_-_106641675	6.790	NM_006825	CKAP4	cytoskeleton-associated protein 4

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.52	5.06e-51	GO:0044237	cellular metabolic process
1.67	7.42e-50	GO:0044260	cellular macromolecule metabolic process
1.24	1.47e-41	GO:0009987	cellular process
1.55	1.53e-40	GO:0043170	macromolecule metabolic process
1.45	3.09e-39	GO:0044238	primary metabolic process
1.40	2.59e-38	GO:0008152	metabolic process
1.81	3.42e-38	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.00	1.53e-35	GO:0010467	gene expression
1.71	1.77e-35	GO:0034641	cellular nitrogen compound metabolic process
1.69	4.47e-35	GO:0006807	nitrogen compound metabolic process
1.87	1.07e-33	GO:0090304	nucleic acid metabolic process
1.94	6.91e-29	GO:0016070	RNA metabolic process
1.68	5.30e-24	GO:0009058	biosynthetic process
1.69	1.89e-23	GO:0044249	cellular biosynthetic process
1.85	3.76e-23	GO:0009059	macromolecule biosynthetic process
1.86	5.90e-23	GO:0034645	cellular macromolecule biosynthetic process
1.65	6.86e-22	GO:0044267	cellular protein metabolic process
2.39	5.62e-20	GO:0006396	RNA processing
3.02	1.15e-18	GO:0006412	translation
1.55	3.54e-17	GO:0071841	cellular component organization or biogenesis at cellular level
1.55	1.61e-16	GO:0071842	cellular component organization at cellular level
1.45	1.67e-15	GO:0071840	cellular component organization or biogenesis
1.49	2.51e-15	GO:0019538	protein metabolic process
1.45	3.53e-15	GO:0016043	cellular component organization
1.45	1.07e-14	GO:0060255	regulation of macromolecule metabolic process
2.74	9.64e-14	GO:0008380	RNA splicing
3.46	2.04e-13	GO:0022415	viral reproductive process
2.45	2.01e-12	GO:0006397	mRNA processing
1.48	2.03e-12	GO:0048518	positive regulation of biological process
2.20	3.71e-12	GO:0016071	mRNA metabolic process
1.37	3.91e-12	GO:0019222	regulation of metabolic process
3.51	1.08e-11	GO:0019058	viral infectious cycle
1.21	1.78e-11	GO:0065007	biological regulation
1.49	2.05e-11	GO:0048522	positive regulation of cellular process
1.81	9.23e-11	GO:0032774	RNA biosynthetic process
1.37	2.09e-10	GO:0031323	regulation of cellular metabolic process
1.21	4.29e-10	GO:0050789	regulation of biological process
2.88	6.88e-10	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.88	6.88e-10	GO:0000398	nuclear mRNA splicing, via spliceosome
1.22	1.02e-09	GO:0050794	regulation of cellular process
1.70	1.51e-09	GO:0010604	positive regulation of macromolecule metabolic process
1.36	1.96e-09	GO:0080090	regulation of primary metabolic process
2.81	2.25e-09	GO:0000375	RNA splicing, via transesterification reactions
1.65	3.16e-09	GO:0009893	positive regulation of metabolic process
1.72	1.16e-08	GO:0032268	regulation of cellular protein metabolic process
1.55	1.39e-08	GO:0006996	organelle organization
1.69	1.79e-08	GO:0051246	regulation of protein metabolic process
2.06	1.95e-08	GO:0034621	cellular macromolecular complex subunit organization
2.79	1.96e-08	GO:0022411	cellular component disassembly
2.79	1.96e-08	GO:0071845	cellular component disassembly at cellular level
1.43	3.23e-08	GO:0048519	negative regulation of biological process
1.41	3.28e-08	GO:0010468	regulation of gene expression
1.64	3.62e-08	GO:0031325	positive regulation of cellular metabolic process
1.45	7.87e-08	GO:0048523	negative regulation of cellular process
2.40	1.02e-07	GO:0010608	posttranscriptional regulation of gene expression
1.79	1.11e-07	GO:0046907	intracellular transport
1.60	1.30e-07	GO:0051641	cellular localization
1.69	1.44e-07	GO:0009892	negative regulation of metabolic process
2.60	2.25e-07	GO:0071843	cellular component biogenesis at cellular level
2.64	3.16e-07	GO:0022613	ribonucleoprotein complex biogenesis
1.71	3.39e-07	GO:0010605	negative regulation of macromolecule metabolic process
1.63	4.59e-07	GO:0051649	establishment of localization in cell
2.08	5.69e-07	GO:0016032	viral reproduction
3.56	6.95e-07	GO:0019080	viral genome expression
3.56	6.95e-07	GO:0019083	viral transcription
2.15	7.07e-07	GO:0044419	interspecies interaction between organisms
3.32	7.68e-07	GO:0006414	translational elongation
1.72	9.29e-07	GO:0043933	macromolecular complex subunit organization
1.69	1.12e-06	GO:0031324	negative regulation of cellular metabolic process
2.32	1.25e-06	GO:0034660	ncRNA metabolic process
1.44	1.38e-06	GO:0043412	macromolecule modification
3.13	2.39e-06	GO:0032984	macromolecular complex disassembly
3.13	2.39e-06	GO:0034623	cellular macromolecular complex disassembly
2.79	6.45e-06	GO:0031016	pancreas development
1.44	6.75e-06	GO:0006464	protein modification process
1.37	8.26e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
3.32	9.02e-06	GO:0006415	translational termination
1.36	1.12e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.65	1.54e-05	GO:0006351	transcription, DNA-dependent
1.54	2.59e-05	GO:0044085	cellular component biogenesis
3.11	2.79e-05	GO:0043241	protein complex disassembly
3.11	2.79e-05	GO:0043624	cellular protein complex disassembly
1.65	2.97e-05	GO:0033554	cellular response to stress
1.33	3.08e-05	GO:0031326	regulation of cellular biosynthetic process
1.33	3.19e-05	GO:0009889	regulation of biosynthetic process
1.77	3.49e-05	GO:0051276	chromosome organization
1.78	3.88e-05	GO:0071822	protein complex subunit organization
4.44	5.20e-05	GO:0006413	translational initiation
2.47	5.75e-05	GO:0051169	nuclear transport
1.67	5.96e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36	6.54e-05	GO:0051252	regulation of RNA metabolic process
1.58	7.13e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.67	7.81e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
2.81	9.29e-05	GO:0031018	endocrine pancreas development
1.65	9.54e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.62	1.14e-04	GO:0009891	positive regulation of biosynthetic process
1.40	1.18e-04	GO:0044281	small molecule metabolic process
2.44	1.21e-04	GO:0006913	nucleocytoplasmic transport
1.99	1.28e-04	GO:0051301	cell division
1.62	1.38e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.54	2.39e-04	GO:0007049	cell cycle
2.33	3.33e-04	GO:0034470	ncRNA processing
1.76	5.09e-04	GO:0044265	cellular macromolecule catabolic process
1.33	9.20e-04	GO:0042221	response to chemical stimulus
1.65	9.40e-04	GO:0051254	positive regulation of RNA metabolic process
1.24	9.67e-04	GO:0032502	developmental process
3.01	1.02e-03	GO:0051168	nuclear export
1.68	1.24e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.67	2.01e-03	GO:0006259	DNA metabolic process
1.66	2.21e-03	GO:0009057	macromolecule catabolic process
1.66	2.21e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.56	2.56e-03	GO:0051128	regulation of cellular component organization
1.69	2.92e-03	GO:0051253	negative regulation of RNA metabolic process
1.32	3.02e-03	GO:0065008	regulation of biological quality
2.53	3.10e-03	GO:0042254	ribosome biogenesis
2.92	3.14e-03	GO:0022618	ribonucleoprotein complex assembly
2.31	3.20e-03	GO:0006417	regulation of translation
2.25	3.36e-03	GO:0035270	endocrine system development
1.66	3.47e-03	GO:0042060	wound healing
1.28	3.64e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.94	3.72e-03	GO:0051130	positive regulation of cellular component organization
2.51	3.75e-03	GO:0006403	RNA localization
1.65	4.20e-03	GO:0010629	negative regulation of gene expression
3.48	4.28e-03	GO:0051701	interaction with host
1.61	4.29e-03	GO:0009719	response to endogenous stimulus
1.43	4.38e-03	GO:0010033	response to organic substance
1.63	4.78e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.60	4.99e-03	GO:0010628	positive regulation of gene expression
1.27	5.46e-03	GO:0051171	regulation of nitrogen compound metabolic process
2.51	5.49e-03	GO:0050657	nucleic acid transport
2.51	5.49e-03	GO:0050658	RNA transport
2.51	5.49e-03	GO:0051236	establishment of RNA localization
1.65	5.78e-03	GO:0000278	mitotic cell cycle
1.59	6.42e-03	GO:0009890	negative regulation of biosynthetic process
3.13	7.60e-03	GO:0031124	mRNA 3'-end processing
1.59	7.78e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.78	7.89e-03	GO:0051247	positive regulation of protein metabolic process
3.23	7.98e-03	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
1.54	8.56e-03	GO:0031399	regulation of protein modification process
1.81	9.10e-03	GO:0034622	cellular macromolecular complex assembly
1.24	9.37e-03	GO:0048856	anatomical structure development
1.61	1.01e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.75	1.02e-02	GO:0071826	ribonucleoprotein complex subunit organization
1.52	1.12e-02	GO:0022402	cell cycle process
1.59	1.23e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.26	1.27e-02	GO:0048731	system development
1.20	1.39e-02	GO:0051716	cellular response to stimulus
1.79	1.70e-02	GO:0016568	chromatin modification
2.99	1.70e-02	GO:0006405	RNA export from nucleus
1.56	1.72e-02	GO:0065003	macromolecular complex assembly
3.83	1.74e-02	GO:0042278	purine nucleoside metabolic process
3.83	1.74e-02	GO:0046128	purine ribonucleoside metabolic process
1.44	1.77e-02	GO:0022607	cellular component assembly
1.68	2.37e-02	GO:0006325	chromatin organization
2.47	2.51e-02	GO:0051028	mRNA transport
1.59	2.53e-02	GO:0009725	response to hormone stimulus
1.67	2.81e-02	GO:0072358	cardiovascular system development
1.67	2.81e-02	GO:0072359	circulatory system development
1.63	2.91e-02	GO:0045892	negative regulation of transcription, DNA-dependent
2.80	3.13e-02	GO:0006353	transcription termination, DNA-dependent
1.95	3.30e-02	GO:0032269	negative regulation of cellular protein metabolic process
1.78	3.67e-02	GO:0018193	peptidyl-amino acid modification
1.79	3.90e-02	GO:0071495	cellular response to endogenous stimulus
1.28	4.05e-02	GO:0006355	regulation of transcription, DNA-dependent
1.66	4.31e-02	GO:0048646	anatomical structure formation involved in morphogenesis
1.40	4.65e-02	GO:0044248	cellular catabolic process
1.95	4.65e-02	GO:0051129	negative regulation of cellular component organization
1.91	4.67e-02	GO:0051248	negative regulation of protein metabolic process
2.23	4.94e-02	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.26	1.19e-55	GO:0044424	intracellular part
1.25	5.61e-55	GO:0005622	intracellular
1.30	7.50e-46	GO:0043229	intracellular organelle
1.30	1.13e-45	GO:0043226	organelle
1.33	1.07e-41	GO:0043231	intracellular membrane-bounded organelle
1.32	2.05e-41	GO:0043227	membrane-bounded organelle
1.50	4.50e-41	GO:0044446	intracellular organelle part
1.49	6.06e-41	GO:0044422	organelle part
1.89	1.60e-39	GO:0031974	membrane-enclosed lumen
1.90	6.86e-39	GO:0070013	intracellular organelle lumen
1.89	1.24e-38	GO:0043233	organelle lumen
1.33	8.94e-37	GO:0005737	cytoplasm
1.88	1.13e-35	GO:0044428	nuclear part
1.44	2.50e-32	GO:0005634	nucleus
1.92	1.27e-31	GO:0031981	nuclear lumen
1.40	1.74e-29	GO:0044444	cytoplasmic part
2.01	5.49e-26	GO:0005654	nucleoplasm
1.54	7.69e-26	GO:0032991	macromolecular complex
2.72	1.04e-25	GO:0030529	ribonucleoprotein complex
1.68	8.99e-21	GO:0005829	cytosol
1.47	1.26e-13	GO:0043228	non-membrane-bounded organelle
1.47	1.26e-13	GO:0043232	intracellular non-membrane-bounded organelle
1.07	1.75e-12	GO:0044464	cell part
1.07	1.85e-12	GO:0005623	cell
2.87	3.42e-10	GO:0005840	ribosome
1.38	1.78e-09	GO:0043234	protein complex
1.82	1.03e-08	GO:0044451	nucleoplasm part
1.55	9.38e-08	GO:0005739	mitochondrion
1.90	5.33e-07	GO:0005730	nucleolus
3.46	3.29e-06	GO:0022626	cytosolic ribosome
6.57	6.00e-06	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.67	2.60e-05	GO:0044429	mitochondrial part
2.58	5.60e-05	GO:0005681	spliceosomal complex
2.47	5.69e-05	GO:0044445	cytosolic part
2.01	4.66e-04	GO:0005759	mitochondrial matrix
1.46	4.81e-04	GO:0005783	endoplasmic reticulum
1.58	5.73e-04	GO:0031967	organelle envelope
2.87	1.09e-03	GO:0071013	catalytic step 2 spliceosome
1.55	1.34e-03	GO:0031975	envelope
3.07	2.76e-03	GO:0015934	large ribosomal subunit
3.73	3.77e-03	GO:0022625	cytosolic large ribosomal subunit
1.98	3.83e-03	GO:0016604	nuclear body
1.91	5.51e-03	GO:0005667	transcription factor complex
1.27	1.39e-02	GO:0031090	organelle membrane
4.67	2.00e-02	GO:0031519	PcG protein complex
3.87	2.38e-02	GO:0001725	stress fiber

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.42	2.17e-46	GO:0005515	protein binding
1.18	1.64e-29	GO:0005488	binding
2.29	9.18e-25	GO:0003723	RNA binding
1.51	4.48e-13	GO:0000166	nucleotide binding
1.39	3.35e-12	GO:0003676	nucleic acid binding
2.88	7.08e-08	GO:0003735	structural constituent of ribosome
1.38	3.99e-05	GO:0035639	purine ribonucleoside triphosphate binding
3.90	6.48e-05	GO:0003743	translation initiation factor activity
1.36	1.16e-04	GO:0017076	purine nucleotide binding
1.36	1.62e-04	GO:0032553	ribonucleotide binding
1.36	1.62e-04	GO:0032555	purine ribonucleotide binding
2.92	7.72e-04	GO:0008135	translation factor activity, nucleic acid binding
3.85	8.62e-04	GO:0043021	ribonucleoprotein binding
1.37	1.80e-03	GO:0005524	ATP binding
1.46	1.91e-03	GO:0030528	transcription regulator activity
1.35	3.28e-03	GO:0030554	adenyl nucleotide binding
1.35	4.96e-03	GO:0032559	adenyl ribonucleotide binding
2.44	5.07e-03	GO:0051082	unfolded protein binding
1.58	6.01e-03	GO:0005198	structural molecule activity
1.83	9.35e-03	GO:0008134	transcription factor binding
1.53	1.31e-02	GO:0046983	protein dimerization activity
2.62	2.30e-02	GO:0031625	ubiquitin protein ligase binding
1.15	2.83e-02	GO:0003824	catalytic activity
1.29	3.67e-02	GO:0016740	transferase activity
3.87	3.95e-02	GO:0003727	single-stranded RNA binding
1.41	4.13e-02	GO:0016772	transferase activity, transferring phosphorus-containing groups