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• Activity deltas table
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Motif ID: ATF6.p2

Z-value: 2.493

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_94024201	40.223		COL1A2	collagen, type I, alpha 2
chr7_+_94023872	28.277	NM_000089	COL1A2	collagen, type I, alpha 2
chrX_+_47441802	24.019		TIMP1	TIMP metallopeptidase inhibitor 1
chr17_-_46688279	23.157		HOXB7	homeobox B7
chrX_+_47441650	21.055	NM_003254	TIMP1	TIMP metallopeptidase inhibitor 1
chr7_+_64498643	20.937		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr13_+_113951537	20.458		LAMP1	lysosomal-associated membrane protein 1
chr5_-_172198160	20.134	NM_004417	DUSP1	dual specificity phosphatase 1
chr3_+_100211554	19.667		TMEM45A	transmembrane protein 45A
chr3_+_100211408	19.651	NM_018004	TMEM45A	transmembrane protein 45A
chr2_+_28615695	19.592		FOSL2	FOS-like antigen 2
chr6_+_7590405	19.549	NM_152551	SNRNP48	small nuclear ribonucleoprotein 48kDa (U11/U12)
chr20_-_39766522	19.535
chr9_+_74526527	18.630		C9orf85	chromosome 9 open reading frame 85
chr6_-_108145507	18.009	NM_198081	SCML4	sex comb on midleg-like 4 (Drosophila)
chr7_-_6523689	17.887	NM_001100603 NM_006854	KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr16_+_69796237	17.700	NM_007014 NM_199423	WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr13_+_45915479	17.245		LOC100190939	uncharacterized LOC100190939
chr5_-_133706717	16.635		CDKL3	cyclin-dependent kinase-like 3
chr2_-_216300770	16.162	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr9_-_131709783	15.904	NM_014908	DOLK	dolichol kinase
chr3_-_187463227	15.506		BCL6	B-cell CLL/lymphoma 6
chr2_+_28615668	15.360		FOSL2	FOS-like antigen 2
chr16_-_3627353	15.251	NM_178844	NLRC3	NLR family, CARD domain containing 3
chr14_+_74551655	15.015	NM_001024674	LIN52	lin-52 homolog (C. elegans)
chr5_-_132299263	14.843	NM_014423	AFF4	AF4/FMR2 family, member 4
chrX_-_100914816	14.840	NM_014782 NM_177949	ARMCX2	armadillo repeat containing, X-linked 2
chr18_+_72922725	14.510	NM_005786	TSHZ1	teashirt zinc finger homeobox 1
chr2_+_28615771	14.467	NM_005253	FOSL2	FOS-like antigen 2
chr3_-_187463474	14.097	NM_001706	BCL6	B-cell CLL/lymphoma 6
chr11_-_59383179	13.852		OSBP	oxysterol binding protein
chr5_-_132299248	13.711		AFF4	AF4/FMR2 family, member 4
chr12_-_122751044	13.547	NM_022916	VPS33A	vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr11_-_113746205	13.365	NM_020886	USP28	ubiquitin specific peptidase 28
chr3_-_57583153	13.316	NM_001660	ARF4	ADP-ribosylation factor 4
chr12_-_122750954	12.986		VPS33A	vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr13_+_113951589	12.932		LAMP1	lysosomal-associated membrane protein 1
chr2_-_172967627	12.753		DLX2	distal-less homeobox 2
chr19_+_50031232	12.284		RCN3	reticulocalbin 3, EF-hand calcium binding domain
chr17_-_7197896	12.073		YBX2	Y box binding protein 2
chr8_-_95274540	11.915	NM_005261 NM_181702	GEM	GTP binding protein overexpressed in skeletal muscle
chr5_+_94890777	11.820	NM_198150	ARSK	arylsulfatase family, member K
chr8_-_95274520	11.731		GEM	GTP binding protein overexpressed in skeletal muscle
chr17_-_7197811	11.699		YBX2	Y box binding protein 2
chr1_-_154193044	11.620		C1orf43	chromosome 1 open reading frame 43
chr19_-_5340700	11.436	NM_002850 NM_130853 NM_130854 NM_130855	PTPRS	protein tyrosine phosphatase, receptor type, S
chr5_-_95297597	11.400	NM_012081	ELL2	elongation factor, RNA polymerase II, 2
chr7_-_19157262	11.379	NM_000474	TWIST1	twist homolog 1 (Drosophila)
chr12_-_112450914	11.204	NM_001193453 NM_001193531 NM_138341	LOC728543 TMEM116	uncharacterized LOC728543 transmembrane protein 116
chr3_-_57583090	11.193		ARF4	ADP-ribosylation factor 4
chr3_-_73673978	11.067	NM_015009	PDZRN3	PDZ domain containing ring finger 3
chr12_-_53448167	11.014		LOC283335	uncharacterized LOC283335
chr2_-_242254984	10.842		HDLBP	high density lipoprotein binding protein
chr17_-_7197866	10.796	NM_015982	YBX2	Y box binding protein 2
chr19_+_47759802	10.682		CCDC9	coiled-coil domain containing 9
chr14_+_68086633	10.621		ARG2	arginase, type II
chr2_-_242255114	10.575	NM_005336	HDLBP	high density lipoprotein binding protein
chr15_-_72668184	10.534		HEXA	hexosaminidase A (alpha polypeptide)
chr13_-_36920396	10.510		SPG20	spastic paraplegia 20 (Troyer syndrome)
chr7_-_37956377	10.505		SFRP4	secreted frizzled-related protein 4
chr11_-_59383167	10.473		OSBP	oxysterol binding protein
chr20_+_30102261	10.404		HM13	histocompatibility (minor) 13
chr6_+_151561094	10.361	NM_005100	AKAP12	A kinase (PRKA) anchor protein 12
chr19_+_32836500	10.244	NM_001136156 NM_014910	ZNF507	zinc finger protein 507
chr19_+_47759730	10.111	NM_015603	CCDC9	coiled-coil domain containing 9
chr20_+_30102237	10.099	NM_030789 NM_178580 NM_178581 NM_178582	HM13	histocompatibility (minor) 13
chr7_-_129592794	10.098	NM_003344 NM_182697	UBE2H	ubiquitin-conjugating enzyme E2H
chr3_-_197686837	9.935	NM_032263	IQCG	IQ motif containing G
chr5_+_102201713	9.913		PAM	peptidylglycine alpha-amidating monooxygenase
chr3_+_171757432	9.756		FNDC3B	fibronectin type III domain containing 3B
chr8_+_26240522	9.756	NM_004331	BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr9_-_127533397	9.471	NM_001489 NM_033334	NR6A1	nuclear receptor subfamily 6, group A, member 1
chr2_-_216300444	9.364		FN1	fibronectin 1
chr9_+_131709970	9.237	NM_015354	NUP188	nucleoporin 188kDa
chr19_+_16187266	9.230		TPM4	tropomyosin 4
chr12_-_106641675	9.230	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr6_+_30294224	9.205
chr1_+_113498984	9.160		LOC100506392	uncharacterized LOC100506392
chr9_+_6757636	8.889	NM_001146694 NM_001146695 NM_015061	KDM4C	lysine (K)-specific demethylase 4C
chr4_-_119757183	8.860		SEC24D	SEC24 family, member D (S. cerevisiae)
chr7_-_37956515	8.838	NM_003014	SFRP4	secreted frizzled-related protein 4
chr3_-_8543327	8.831		LOC100288428	uncharacterized LOC100288428
chr19_+_49866986	8.824	NM_001197302 NM_001197301 NM_014419	DKKL1	dickkopf-like 1
chr11_-_59383616	8.764	NM_002556	OSBP	oxysterol binding protein
chr7_-_129592711	8.731	NM_001202498	UBE2H	ubiquitin-conjugating enzyme E2H
chr12_+_112451229	8.723
chr3_-_57582866	8.704		ARF4	ADP-ribosylation factor 4
chr13_-_45915277	8.686	NM_003295	TPT1	tumor protein, translationally-controlled 1
chr14_-_45431121	8.659	NM_017658	KLHL28	kelch-like 28 (Drosophila)
chr9_+_131709991	8.626		NUP188	nucleoporin 188kDa
chr7_-_8301767	8.465	NM_001136020	ICA1	islet cell autoantigen 1, 69kDa
chr16_-_79634610	8.452	NM_001031804 NM_005360	MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
chr4_+_166299942	8.396	NM_001873	CPE	carboxypeptidase E
chrX_+_16804531	8.352	NM_001168683 NM_018360	TXLNG	taxilin gamma
chr22_+_38597938	8.325	NM_001161572 NM_001161574 NM_012323	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr15_-_50978983	8.302	NM_017672	TRPM7	transient receptor potential cation channel, subfamily M, member 7
chr8_+_133787556	8.290	NM_016018 NM_032205 NM_198513	PHF20L1	PHD finger protein 20-like 1
chr3_-_20227618	8.208	NM_001012409 NM_001012410 NM_001012411 NM_001012412 NM_001012413 NM_138484 NM_001199251 NM_001199252 NM_001199253 NM_001199254 NM_001199255 NM_001199256 NM_001199257	SGOL1	shugoshin-like 1 (S. pombe)
chr13_-_45915308	8.181		TPT1	tumor protein, translationally-controlled 1
chr6_+_101846668	8.145		GRIK2	glutamate receptor, ionotropic, kainate 2
chr3_-_57583080	8.123		ARF4	ADP-ribosylation factor 4
chr1_+_154193294	8.122	NM_014847	UBAP2L	ubiquitin associated protein 2-like
chr1_-_47184790	8.091
chr1_+_36689996	8.016	NM_005119	THRAP3	thyroid hormone receptor associated protein 3
chr13_+_113951461	8.003	NM_005561	LAMP1	lysosomal-associated membrane protein 1
chr1_+_37940074	7.942	NM_025079	ZC3H12A	zinc finger CCCH-type containing 12A
chr18_+_9708269	7.939		RAB31	RAB31, member RAS oncogene family
chr2_-_176866925	7.923	NM_030650	KIAA1715	KIAA1715
chr19_+_5681016	7.914	NM_198704 NM_198705 NM_198533 NM_198707 NM_198706 NM_198708	HSD11B1L	hydroxysteroid (11-beta) dehydrogenase 1-like
chr11_+_113930430	7.904	NM_006006	ZBTB16	zinc finger and BTB domain containing 16
chr18_+_23806385	7.850	NM_005640	TAF4B	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr14_+_101292451	7.812		MEG3	maternally expressed 3 (non-protein coding)
chr17_+_7211260	7.812	NM_001143761	EIF5A	eukaryotic translation initiation factor 5A
chr3_+_122785855	7.792	NM_006810	PDIA5	protein disulfide isomerase family A, member 5
chr14_+_68086570	7.788	NM_001172	ARG2	arginase, type II
chr10_-_128077062	7.773		ADAM12	ADAM metallopeptidase domain 12
chr11_+_113930296	7.744		ZBTB16	zinc finger and BTB domain containing 16
chr4_-_119757288	7.743	NM_014822	SEC24D	SEC24 family, member D (S. cerevisiae)
chr2_-_20251788	7.731	NM_014713	LAPTM4A	lysosomal protein transmembrane 4 alpha
chr22_+_38864015	7.714	NM_006855 NM_016657	KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr14_-_93799360	7.712		BTBD7	BTB (POZ) domain containing 7
chr16_-_75498582	7.598	NM_145254	TMEM170A	transmembrane protein 170A
chr17_-_19880991	7.567	NM_007202	AKAP10	A kinase (PRKA) anchor protein 10
chr14_+_74486049	7.564	NM_025057	C14orf45	chromosome 14 open reading frame 45
chrX_-_47509993	7.511	NM_001114123 NM_005229	ELK1	ELK1, member of ETS oncogene family
chr16_+_68057144	7.507	NM_017803	DUS2L	dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
chr3_-_119182423	7.440	NM_018266	TMEM39A	transmembrane protein 39A
chr8_+_104427590	7.413		DCAF13	DDB1 and CUL4 associated factor 13
chr6_+_127587984	7.398		RNF146	ring finger protein 146
chr10_-_101769640	7.397	NM_015221	DNMBP	dynamin binding protein
chr16_-_31470582	7.366
chr5_+_68389775	7.365	NM_001251969 NM_022902 NM_024055	SLC30A5	solute carrier family 30 (zinc transporter), member 5
chr2_+_79347610	7.360		REG1A	regenerating islet-derived 1 alpha
chr21_+_47545896	7.357		COL6A2	collagen, type VI, alpha 2
chr9_-_130477918	7.346	NM_001002913	PTRH1	peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr7_-_8301681	7.295	NM_022307	ICA1	islet cell autoantigen 1, 69kDa
chr2_-_220408264	7.288	NM_024536	CHPF	chondroitin polymerizing factor
chr1_+_160313172	7.285		NCSTN	nicastrin
chr19_+_16187315	7.282		TPM4	tropomyosin 4
chr17_+_7210929	7.280		EIF5A	eukaryotic translation initiation factor 5A
chrX_-_47509864	7.253		ELK1	ELK1, member of ETS oncogene family
chr17_+_79885567	7.249		LOC92659	uncharacterized LOC92659
chr3_+_129159089	7.237		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr10_+_35416384	7.237	NM_181571 NM_183060	CREM	cAMP responsive element modulator
chr12_-_14720790	7.230	NM_024829	PLBD1	phospholipase B domain containing 1
chr4_-_186456580	7.230	NM_001114107 NM_014476	PDLIM3	PDZ and LIM domain 3
chr18_+_9708299	7.215		RAB31	RAB31, member RAS oncogene family
chr14_-_81687265	7.206	NM_015859	GTF2A1	general transcription factor IIA, 1, 19/37kDa
chr13_-_45915203	7.163		TPT1	tumor protein, translationally-controlled 1
chr8_+_128806720	7.131		PVT1	Pvt1 oncogene (non-protein coding)
chr3_+_129159138	7.113		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr3_+_129159150	7.087		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr5_+_102201526	7.079	NM_000919 NM_001177306 NM_138766 NM_138821 NM_138822	PAM	peptidylglycine alpha-amidating monooxygenase
chr10_-_128077011	7.037		ADAM12	ADAM metallopeptidase domain 12
chr1_+_160313061	7.009	NM_015331	NCSTN	nicastrin
chr7_-_73184535	6.975	NM_001306	CLDN3	claudin 3
chr6_+_31982538	6.899	NM_001242823 NM_001252204 NM_007293 NM_001002029	LOC100293534 C4A C4B	complement C4-B-like complement component 4A (Rodgers blood group) complement component 4B (Chido blood group)
chr11_-_35547144	6.873	NM_001001991 NM_015430	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr9_+_6757919	6.866		KDM4C	lysine (K)-specific demethylase 4C
chr3_+_129159075	6.863		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chrX_+_100805415	6.818	NM_016608	ARMCX1	armadillo repeat containing, X-linked 1
chr3_-_139108486	6.779
chr10_+_22634373	6.756	NM_001253854 NM_001253855 NM_012443 NM_172242	SPAG6	sperm associated antigen 6
chr12_+_28343390	6.756
chr1_+_36690038	6.731		THRAP3	thyroid hormone receptor associated protein 3
chr3_+_129158949	6.721	NM_018262 NM_052985 NM_052989 NM_052990	IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr7_+_116593354	6.701	NM_018412 NM_021908	ST7	suppression of tumorigenicity 7
chr6_-_70506472	6.680		LMBRD1	LMBR1 domain containing 1
chr7_+_128470462	6.671	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr19_+_18794487	6.656		CRTC1	CREB regulated transcription coactivator 1
chr14_+_101292483	6.630
chr4_-_54930706	6.629		CHIC2	cysteine-rich hydrophobic domain 2
chr12_+_56552141	6.606		MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle
chr13_-_95364248	6.572	NM_007084	SOX21	SRY (sex determining region Y)-box 21
chr7_+_99775346	6.566		STAG3	stromal antigen 3
chr17_-_13505217	6.562	NM_006042	HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr10_+_121411071	6.554		BAG3	BCL2-associated athanogene 3
chr11_-_119234859	6.551	NM_171997	USP2	ubiquitin specific peptidase 2
chr10_+_121410751	6.516	NM_004281	BAG3	BCL2-associated athanogene 3
chr16_-_1525006	6.505		CLCN7	chloride channel 7
chr1_-_35497249	6.493		ZMYM6	zinc finger, MYM-type 6
chr1_-_31712733	6.460	NM_024522	NKAIN1	Na+/K+ transporting ATPase interacting 1
chr12_-_14720553	6.450		PLBD1	phospholipase B domain containing 1
chr2_-_211035913	6.409	NM_152519	C2orf67	chromosome 2 open reading frame 67
chr14_-_64970319	6.396	NM_006977	ZBTB25	zinc finger and BTB domain containing 25
chr10_+_121411042	6.388		BAG3	BCL2-associated athanogene 3
chr10_+_121410891	6.386		BAG3	BCL2-associated athanogene 3
chr1_-_235812994	6.363	NM_001098722	GNG4	guanine nucleotide binding protein (G protein), gamma 4
chr2_-_1748285	6.343	NM_012293	PXDN	peroxidasin homolog (Drosophila)
chr8_+_104427637	6.324		DCAF13	DDB1 and CUL4 associated factor 13
chr7_+_44646180	6.299		OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr17_-_46687925	6.295		HOXB7	homeobox B7
chr11_-_62598552	6.273		STX5	syntaxin 5
chr2_+_236402948	6.263		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr3_+_142442855	6.245
chr1_+_37940129	6.232		ZC3H12A	zinc finger CCCH-type containing 12A
chr14_-_74485813	6.198	NM_001249	ENTPD5	ectonucleoside triphosphate diphosphohydrolase 5
chr7_-_72992888	6.193		TBL2	transducin (beta)-like 2
chr14_+_23305913	6.146		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr19_-_4457789	6.137	NM_025241	UBXN6	UBX domain protein 6

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.44	3.02e-13	GO:0043170	macromolecule metabolic process
2.27	1.51e-12	GO:0006351	transcription, DNA-dependent
2.16	7.93e-12	GO:0032774	RNA biosynthetic process
1.44	4.69e-11	GO:0044260	cellular macromolecule metabolic process
1.18	4.82e-11	GO:0009987	cellular process
1.26	2.64e-09	GO:0065007	biological regulation
1.47	3.53e-09	GO:0031323	regulation of cellular metabolic process
1.70	6.50e-09	GO:0010467	gene expression
1.61	9.44e-09	GO:0051252	regulation of RNA metabolic process
1.62	1.16e-08	GO:0006355	regulation of transcription, DNA-dependent
1.54	1.49e-08	GO:0009889	regulation of biosynthetic process
1.55	1.52e-08	GO:0031326	regulation of cellular biosynthetic process
1.42	2.40e-08	GO:0019222	regulation of metabolic process
1.27	2.98e-08	GO:0050794	regulation of cellular process
1.57	3.52e-08	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.52	5.50e-08	GO:0051171	regulation of nitrogen compound metabolic process
1.26	6.35e-08	GO:0050789	regulation of biological process
1.55	7.21e-08	GO:0010556	regulation of macromolecule biosynthetic process
1.44	7.91e-08	GO:0080090	regulation of primary metabolic process
1.53	8.31e-08	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29	1.06e-07	GO:0044238	primary metabolic process
1.29	1.14e-07	GO:0044237	cellular metabolic process
1.26	1.23e-07	GO:0008152	metabolic process
1.53	2.06e-07	GO:0010468	regulation of gene expression
1.73	2.68e-07	GO:0009653	anatomical structure morphogenesis
1.44	3.17e-07	GO:0060255	regulation of macromolecule metabolic process
1.67	3.41e-07	GO:0009059	macromolecule biosynthetic process
1.66	3.54e-07	GO:0016070	RNA metabolic process
1.66	9.50e-07	GO:0034645	cellular macromolecule biosynthetic process
1.87	2.87e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.38	5.24e-06	GO:0032502	developmental process
2.53	2.19e-05	GO:0001501	skeletal system development
1.52	2.19e-05	GO:0048523	negative regulation of cellular process
2.05	4.42e-05	GO:0009887	organ morphogenesis
1.50	4.71e-05	GO:0090304	nucleic acid metabolic process
1.67	7.31e-05	GO:0051641	cellular localization
1.43	7.34e-05	GO:0048518	positive regulation of biological process
1.74	8.61e-05	GO:0008104	protein localization
1.46	1.21e-04	GO:0048519	negative regulation of biological process
1.38	2.00e-04	GO:0048856	anatomical structure development
1.97	2.08e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.63	2.94e-04	GO:0033036	macromolecule localization
1.44	3.11e-04	GO:0044249	cellular biosynthetic process
1.76	4.75e-04	GO:0050793	regulation of developmental process
1.42	8.24e-04	GO:0048522	positive regulation of cellular process
1.86	1.04e-03	GO:0009790	embryo development
1.41	1.09e-03	GO:0009058	biosynthetic process
1.98	1.11e-03	GO:0051253	negative regulation of RNA metabolic process
1.89	1.12e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.86	1.18e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.99	1.25e-03	GO:0045892	negative regulation of transcription, DNA-dependent
2.91	1.29e-03	GO:0009952	anterior/posterior pattern formation
1.36	1.52e-03	GO:0019538	protein metabolic process
1.48	1.75e-03	GO:0006464	protein modification process
1.72	1.77e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.34	1.96e-03	GO:0006807	nitrogen compound metabolic process
1.72	2.13e-03	GO:0031324	negative regulation of cellular metabolic process
4.37	2.36e-03	GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.65	2.42e-03	GO:0010941	regulation of cell death
1.83	2.54e-03	GO:0009890	negative regulation of biosynthetic process
1.79	2.64e-03	GO:2000026	regulation of multicellular organismal development
3.02	2.77e-03	GO:0016055	Wnt receptor signaling pathway
1.89	2.85e-03	GO:0010629	negative regulation of gene expression
3.87	2.97e-03	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
1.46	3.18e-03	GO:0048513	organ development
2.08	3.21e-03	GO:0007243	intracellular protein kinase cascade
2.08	3.21e-03	GO:0023014	signal transduction via phosphorylation event
1.72	3.67e-03	GO:0015031	protein transport
2.00	3.73e-03	GO:0072358	cardiovascular system development
2.00	3.73e-03	GO:0072359	circulatory system development
1.64	4.01e-03	GO:0043067	regulation of programmed cell death
2.14	4.05e-03	GO:0048598	embryonic morphogenesis
2.01	4.17e-03	GO:0048646	anatomical structure formation involved in morphogenesis
2.10	4.22e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.95	4.54e-03	GO:0034613	cellular protein localization
1.86	4.64e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.71	4.71e-03	GO:0009888	tissue development
1.31	4.80e-03	GO:0007275	multicellular organismal development
1.33	5.11e-03	GO:0034641	cellular nitrogen compound metabolic process
2.29	5.49e-03	GO:0001944	vasculature development
1.36	5.50e-03	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.94	5.53e-03	GO:0070727	cellular macromolecule localization
3.85	6.46e-03	GO:0034130	toll-like receptor 1 signaling pathway
3.85	6.46e-03	GO:0034134	toll-like receptor 2 signaling pathway
1.65	6.64e-03	GO:0009892	negative regulation of metabolic process
1.84	7.02e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.38	7.14e-03	GO:0044267	cellular protein metabolic process
1.69	7.35e-03	GO:0045184	establishment of protein localization
1.43	8.57e-03	GO:0043412	macromolecule modification
1.62	9.03e-03	GO:0042981	regulation of apoptosis
3.95	9.30e-03	GO:0034138	toll-like receptor 3 signaling pathway
1.34	9.37e-03	GO:0048731	system development
1.59	9.90e-03	GO:0051649	establishment of localization in cell
2.36	1.00e-02	GO:0000165	MAPKKK cascade
1.54	1.36e-02	GO:0051239	regulation of multicellular organismal process
3.83	1.41e-02	GO:0002756	MyD88-independent toll-like receptor signaling pathway
2.27	1.79e-02	GO:0001568	blood vessel development
1.96	2.11e-02	GO:0032583	regulation of gene-specific transcription
1.71	2.33e-02	GO:0016192	vesicle-mediated transport
3.50	2.45e-02	GO:0008063	Toll signaling pathway
3.50	2.45e-02	GO:0034142	toll-like receptor 4 signaling pathway
2.68	2.48e-02	GO:0048562	embryonic organ morphogenesis
3.32	2.70e-02	GO:0002224	toll-like receptor signaling pathway
6.64	2.81e-02	GO:0048199	vesicle targeting, to, from or within Golgi
1.50	3.00e-02	GO:0035556	intracellular signal transduction
1.27	3.21e-02	GO:0023052	signaling
2.36	3.82e-02	GO:0048514	blood vessel morphogenesis
2.18	4.18e-02	GO:0035295	tube development
2.05	4.45e-02	GO:0007389	pattern specification process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.26	9.68e-14	GO:0043227	membrane-bounded organelle
1.26	1.24e-13	GO:0043231	intracellular membrane-bounded organelle
1.18	2.10e-13	GO:0044424	intracellular part
1.17	7.30e-12	GO:0005622	intracellular
1.20	9.11e-11	GO:0043226	organelle
1.20	9.42e-11	GO:0043229	intracellular organelle
1.31	2.45e-08	GO:0005634	nucleus
1.19	2.13e-06	GO:0005737	cytoplasm
1.24	7.22e-05	GO:0044422	organelle part
1.23	2.21e-04	GO:0044446	intracellular organelle part
1.65	5.02e-04	GO:0005794	Golgi apparatus
1.21	5.04e-04	GO:0044444	cytoplasmic part
1.60	9.93e-04	GO:0005783	endoplasmic reticulum
1.37	2.78e-03	GO:0043233	organelle lumen
1.80	2.91e-03	GO:0044431	Golgi apparatus part
1.36	3.29e-03	GO:0031974	membrane-enclosed lumen
1.45	3.67e-03	GO:0012505	endomembrane system
1.68	6.86e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
1.67	6.91e-03	GO:0031988	membrane-bounded vesicle
3.02	8.51e-03	GO:0005788	endoplasmic reticulum lumen
1.35	9.53e-03	GO:0070013	intracellular organelle lumen
1.83	1.06e-02	GO:0000139	Golgi membrane
1.39	1.13e-02	GO:0031981	nuclear lumen
1.62	1.50e-02	GO:0031410	cytoplasmic vesicle
1.46	1.59e-02	GO:0005654	nucleoplasm
3.76	2.11e-02	GO:0005793	ER-Golgi intermediate compartment
1.59	2.40e-02	GO:0031982	vesicle
1.34	2.42e-02	GO:0031090	organelle membrane
1.61	2.55e-02	GO:0044432	endoplasmic reticulum part
2.99	2.74e-02	GO:0042470	melanosome
2.99	2.74e-02	GO:0048770	pigment granule
1.33	3.68e-02	GO:0044428	nuclear part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.25	1.81e-15	GO:0001071	nucleic acid binding transcription factor activity
2.25	1.81e-15	GO:0003700	sequence-specific DNA binding transcription factor activity
2.35	1.01e-11	GO:0043565	sequence-specific DNA binding
1.28	1.26e-10	GO:0005515	protein binding
1.90	3.01e-08	GO:0030528	transcription regulator activity
1.13	6.31e-07	GO:0005488	binding
1.46	1.25e-05	GO:0003677	DNA binding
2.23	7.02e-05	GO:0000988	protein binding transcription factor activity
2.23	7.02e-05	GO:0000989	transcription factor binding transcription factor activity
2.19	1.62e-04	GO:0003712	transcription cofactor activity
4.23	4.13e-03	GO:0003707	steroid hormone receptor activity
2.38	7.12e-03	GO:0000975	regulatory region DNA binding
2.38	7.12e-03	GO:0001067	regulatory region nucleic acid binding
2.38	7.12e-03	GO:0044212	transcription regulatory region DNA binding
4.00	8.12e-03	GO:0004879	ligand-dependent nuclear receptor activity
2.03	3.16e-02	GO:0008134	transcription factor binding
1.26	4.92e-02	GO:0003676	nucleic acid binding