Motif ID: AUGGCAC

Z-value: 1.152


Mature miRNA associated with seed AUGGCAC:

NamemiRBase Accession
hsa-miR-183 MIMAT0000261



Activity profile for motif AUGGCAC.

activity profile for motif AUGGCAC


Sorted Z-values histogram for motif AUGGCAC

Sorted Z-values for motif AUGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AUGGCAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_151985828 22.490 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr19_+_7504573 21.428 NM_001130955
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr3_+_152017193 19.942 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr5_+_65222381 19.189 NM_001006600
NM_001253697
NM_001253698
NM_001253699
NM_001253701
NM_018695
ERBB2IP





erbb2 interacting protein





chr19_+_7459964 18.614 NM_015318
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr12_-_76953561 18.263 NM_001003712
NM_020841
OSBPL8

oxysterol binding protein-like 8

chr5_-_133561805 16.492 NM_002715
PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
chr18_+_29671817 16.073 NM_016271
RNF138
ring finger protein 138
chr12_-_92539614 15.313 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr2_-_161350304 15.091 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chrX_-_20284708 15.026 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr13_-_24007822 14.983 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr15_+_57511616 14.911 NM_207040
TCF12
transcription factor 12
chr15_+_57210823 14.780 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr18_+_29672568 14.691 NM_001191324
NM_198128
RNF138

ring finger protein 138

chr8_+_26150731 14.599 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr8_+_26149004 14.176 NM_002717
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr15_-_90645704 14.129 NM_002168
IDH2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr6_-_159239269 13.237 NM_003379
EZR
ezrin
chr5_-_142783975 12.107 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr10_+_74033676 12.075 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr11_+_11862955 11.442 NM_017944
USP47
ubiquitin specific peptidase 47
chr1_-_94374986 11.159 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr14_+_102276125 11.153 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr7_-_16685360 11.113 NM_020319
ANKMY2
ankyrin repeat and MYND domain containing 2
chr8_+_97274158 10.992 NM_014754
PTDSS1
phosphatidylserine synthase 1
chr8_+_6565870 10.546 NM_018361
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr1_+_70671331 10.292 NM_001190987
NM_004768
SRSF11

serine/arginine-rich splicing factor 11

chr6_-_159240433 9.542 NM_001111077
EZR
ezrin
chr3_+_140660639 9.055 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr5_-_64064483 9.039 NM_173829
SREK1IP1
SREK1-interacting protein 1
chr2_-_55920947 9.015 NM_033109
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr16_+_85645014 8.846 NM_001134473
KIAA0182
KIAA0182
chr8_+_98656329 8.539 NM_178812
MTDH
metadherin
chr11_-_93276513 8.327 NM_020179
C11orf75
chromosome 11 open reading frame 75
chr5_+_271700 8.137 NM_013232
PDCD6
programmed cell death 6
chr6_+_7107986 8.062 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr12_+_64798050 7.860 NM_007235
XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr2_+_106468203 7.732 NM_001004720
NCK2
NCK adaptor protein 2
chr10_+_112631552 7.717 NM_001199492
NM_014456
NM_145341
PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chr14_-_99737821 7.418 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr16_+_85646923 7.384 NM_014615
KIAA0182
KIAA0182
chr2_+_106361404 7.255 NM_001004722
NM_003581
NCK2

NCK adaptor protein 2

chr6_-_7910716 7.178 NM_030810
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr5_+_133861685 6.914 NM_015288
PHF15
PHD finger protein 15
chr6_+_161412807 6.785 NM_005922
NM_006724
MAP3K4

mitogen-activated protein kinase kinase kinase 4

chr11_-_47510518 6.756 NM_001025596
NM_001172640
CELF1

CUGBP, Elav-like family member 1

chr6_+_88182624 6.747 NM_001168398
NM_006416
SLC35A1

solute carrier family 35 (CMP-sialic acid transporter), member A1

chr7_+_101460881 6.604 NM_181552
CUX1
cut-like homeobox 1
chr11_+_125439294 6.599 NM_001007277
NM_004879
EI24

etoposide induced 2.4 mRNA

chr1_-_235490801 6.591 NM_001206794
ARID4B
AT rich interactive domain 4B (RBP1-like)
chr5_-_142815076 6.463 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr5_-_59783885 6.224 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_65810020 6.002 NM_017743
NM_130434
NM_197961
DPP8


dipeptidyl-peptidase 8


chr8_+_110346549 5.831 NM_001193557
NM_020189
ENY2

enhancer of yellow 2 homolog (Drosophila)

chr6_+_163835668 5.809 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr1_-_67896098 5.780 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chr14_-_88737160 5.702 NM_138318
KCNK10
potassium channel, subfamily K, member 10
chr13_+_20532906 5.585 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr15_+_64388082 5.573 NM_001242933
NM_003099
NM_148955
SNX1


sorting nexin 1


chr12_+_72148653 5.378 NM_014999
RAB21
RAB21, member RAS oncogene family
chr19_-_3985460 5.273 NM_001961
EEF2
eukaryotic translation elongation factor 2
chrX_-_110654373 5.265 NM_000555
DCX
doublecortin
chr2_-_145277879 5.245 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr6_-_7910278 5.226 NM_001145549
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr5_-_142783225 5.220 NM_000176
NM_001020825
NM_001024094
NM_001204258
NM_001204259
NM_001204260
NM_001204261
NM_001204262
NM_001204263
NM_001204264
NM_001204265
NR3C1










nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)










chr14_+_102228134 5.180 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr2_+_169312793 5.125 NM_203463
CERS6
ceramide synthase 6
chr14_-_88793250 5.117 NM_021161
KCNK10
potassium channel, subfamily K, member 10
chr2_+_219264477 4.958 NM_021198
NM_182642
CTDSP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1

chr10_+_22610138 4.854 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr1_-_235491494 4.828 NM_016374
NM_031371
ARID4B

AT rich interactive domain 4B (RBP1-like)

chr15_-_60919642 4.818 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chrX_+_12993224 4.647 NM_021109
TMSB4X
thymosin beta 4, X-linked
chr6_-_132834165 4.570 NM_003569
STX7
syntaxin 7
chr13_+_41363546 4.521 NM_014252
SLC25A15
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
chr6_+_7107799 4.440 NM_001168344
RREB1
ras responsive element binding protein 1
chr14_+_105886146 4.370 NM_001203258
NM_004689
MTA1

metastasis associated 1

chr17_-_60142598 4.284 NM_005121
MED13
mediator complex subunit 13
chr15_-_65809603 4.231 NM_197960
DPP8
dipeptidyl-peptidase 8
chr1_-_1822516 4.222 NM_002074
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr15_-_60884615 4.218 NM_134262
RORA
RAR-related orphan receptor A
chr2_-_100106478 4.135 NM_001037872
NM_016316
REV1

REV1 homolog (S. cerevisiae)

chr13_-_25861608 3.990 NM_004685
MTMR6
myotubularin related protein 6
chr15_-_64673569 3.924 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr3_+_169940214 3.807 NM_002740
PRKCI
protein kinase C, iota
chr15_-_61521478 3.761 NM_134261
RORA
RAR-related orphan receptor A
chr18_-_53255734 3.588 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr9_-_114247024 3.550 NM_001080398
KIAA0368
KIAA0368
chr8_+_64081108 3.494 NM_152758
YTHDF3
YTH domain family, member 3
chr11_-_47198675 3.457 NM_001242832
NM_032389
ARFGAP2

ADP-ribosylation factor GTPase activating protein 2

chr9_+_112542496 3.247 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr5_-_32174397 3.238 NM_022130
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr11_-_35441501 3.219 NM_001195728
NM_001252652
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr14_-_68283293 3.212 NM_015346
ZFYVE26
zinc finger, FYVE domain containing 26
chr11_+_117049838 3.151 NM_001040455
SIDT2
SID1 transmembrane family, member 2
chr2_-_128100673 3.131 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr13_+_20532788 3.006 NM_003453
NM_197968
NM_001190964
ZMYM2


zinc finger, MYM-type 2


chr3_-_194188967 2.883 NM_024524
ATP13A3
ATPase type 13A3
chr17_-_37607314 2.777 NM_004774
MED1
mediator complex subunit 1
chr3_-_100120224 2.704 NM_014820
TOMM70A
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr6_+_64356430 2.669 NM_015153
PHF3
PHD finger protein 3
chr3_-_125094003 2.645 NM_021964
ZNF148
zinc finger protein 148
chr20_-_39928708 2.640 NM_015035
ZHX3
zinc fingers and homeoboxes 3
chr15_-_52861177 2.628 NM_006628
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr7_+_155089483 2.611 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chrX_-_110655384 2.463 NM_178151
NM_001195553
NM_178152
NM_178153
DCX



doublecortin



chr1_-_68299047 2.454 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr3_+_171757413 2.411 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr22_+_40573879 2.370 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr10_-_114206640 2.365 NM_022494
ZDHHC6
zinc finger, DHHC-type containing 6
chr14_+_90863302 2.340 NM_006888
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr22_+_40440664 2.334 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr3_+_130569368 2.067 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr3_+_171758289 2.064 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr17_-_74733419 1.926 NM_001195427
NM_003016
SRSF2

serine/arginine-rich splicing factor 2

chr12_+_98909331 1.849 NM_001032283
NM_001032284
NM_003276
TMPO


thymopoietin


chr2_+_219263060 1.827 NM_001206878
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr14_+_55518313 1.729 NM_144578
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr7_+_69063768 1.664 NM_001127231
NM_001127232
NM_015570
AUTS2


autism susceptibility candidate 2


chr7_+_39663140 1.629 NM_005402
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr8_-_29207795 1.558 NM_001394
DUSP4
dual specificity phosphatase 4
chr10_+_22605300 1.545 NM_001204062
NM_012071
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr3_-_160283361 1.495 NM_002268
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr9_+_706744 1.485 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr5_-_108745569 1.481 NM_014819
PJA2
praja ring finger 2
chr6_-_109415514 1.435 NM_014454
SESN1
sestrin 1
chr11_-_35441099 1.307 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_+_185014449 1.289 NM_007212
RNF2
ring finger protein 2
chr1_+_215178884 1.211 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr9_-_135819995 1.184 NM_000368
NM_001162426
NM_001162427
TSC1


tuberous sclerosis 1


chr18_+_48086402 1.178 NM_002747
MAPK4
mitogen-activated protein kinase 4
chr18_+_67956136 1.129 NM_004232
SOCS6
suppressor of cytokine signaling 6
chr1_-_160254923 1.122 NM_001193644
NM_002857
PEX19

peroxisomal biogenesis factor 19

chr8_-_93029864 1.113 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_236767787 1.064 NM_018072
HEATR1
HEAT repeat containing 1
chr8_-_93107442 1.040 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr6_-_109330752 1.030 NM_001199933
SESN1
sestrin 1
chr1_+_203595897 1.023 NM_001001396
NM_001684
ATP2B4

ATPase, Ca++ transporting, plasma membrane 4

chr21_-_30365111 1.006 NM_015565
LTN1
listerin E3 ubiquitin protein ligase 1
chr10_+_114709963 1.002 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr10_+_31608097 1.001 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr1_+_181452685 0.864 NM_000721
NM_001205293
NM_001205294
CACNA1E


calcium channel, voltage-dependent, R type, alpha 1E subunit


chr2_+_204571197 0.843 NM_001243077
NM_001243078
NM_006139
CD28


CD28 molecule


chr12_+_27397077 0.798 NM_015000
STK38L
serine/threonine kinase 38 like
chr6_+_37137882 0.734 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr10_+_31610063 0.722 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr16_+_14164879 0.706 NM_014048
MKL2
MKL/myocardin-like 2
chr2_+_192109879 0.704 NM_001130158
NM_012223
NM_001161819
MYO1B


myosin IB


chr14_+_78870092 0.683 NM_004796
NRXN3
neurexin 3
chr17_-_16097882 0.664 NM_001190438
NM_001190440
NCOR1

nuclear receptor corepressor 1

chr5_+_142150291 0.603 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chr20_-_14318200 0.597 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr8_-_29206321 0.560 NM_057158
DUSP4
dual specificity phosphatase 4
chr4_-_129209983 0.484 NM_006320
PGRMC2
progesterone receptor membrane component 2
chr10_+_64893003 0.472 NM_030759
NRBF2
nuclear receptor binding factor 2
chr2_+_159313466 0.466 NM_001005476
NM_003628
PKP4

plakophilin 4

chr20_+_9049660 0.454 NM_001172646
PLCB4
phospholipase C, beta 4
chr7_+_145813452 0.412 NM_014141
CNTNAP2
contactin associated protein-like 2
chr19_-_14316980 0.410 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr20_+_9288446 0.386 NM_000933
PLCB4
phospholipase C, beta 4
chr9_-_98270321 0.384 NM_001083604
NM_001083605
PTCH1

patched 1

chr5_+_179159799 0.379 NM_014757
MAML1
mastermind-like 1 (Drosophila)
chr20_+_9198036 0.371 NM_182797
PLCB4
phospholipase C, beta 4
chr12_+_4382882 0.366 NM_001759
CCND2
cyclin D2
chr4_+_170541656 0.319 NM_001243372
NM_001829
NM_173872
CLCN3


chloride channel 3


chr8_-_93107881 0.296 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr8_-_57123858 0.251 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr5_-_58882274 0.248 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_111944967 0.153 NM_001082969
NM_001082970
NM_018195
C11orf57


chromosome 11 open reading frame 57


chr9_-_98270830 0.146 NM_000264
PTCH1
patched 1
chr9_-_98279246 0.117 NM_001083602
NM_001083603
PTCH1

patched 1

chr9_-_98269686 0.061 NM_001083606
PTCH1
patched 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.62 9.62e-05 GO:0050794 regulation of cellular process
1.54 1.47e-04 GO:0065007 biological regulation
1.56 2.43e-04 GO:0050789 regulation of biological process
1.30 2.32e-03 GO:0009987 cellular process
2.02 1.20e-02 GO:0048518 positive regulation of biological process
1.76 2.29e-02 GO:0019222 regulation of metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.56 5.58e-03 GO:0005634 nucleus
1.26 5.81e-03 GO:0044424 intracellular part
1.24 1.14e-02 GO:0005622 intracellular
1.31 1.25e-02 GO:0043229 intracellular organelle
1.31 1.36e-02 GO:0043226 organelle
1.97 1.84e-02 GO:0031974 membrane-enclosed lumen
2.37 2.03e-02 GO:0005654 nucleoplasm
1.52 2.04e-02 GO:0044446 intracellular organelle part
2.11 2.30e-02 GO:0031981 nuclear lumen
1.99 2.65e-02 GO:0044428 nuclear part
87.96 2.70e-02 GO:0070852 cell body fiber
1.50 3.16e-02 GO:0044422 organelle part
4.83 4.19e-02 GO:0016604 nuclear body

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.52 3.00e-04 GO:0005515 protein binding
131.94 9.67e-03 GO:0071535 RING-like zinc finger domain binding
1.22 2.66e-02 GO:0005488 binding