Motif ID: CREB1.p2

Z-value: 1.890


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2083948230.591.3e-21Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_17104266 36.214 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr8_-_17104103 34.043 CNOT7
CCR4-NOT transcription complex, subunit 7
chr3_-_49066858 34.033 NM_000884
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr3_-_49066760 33.510 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr3_-_49066813 31.594 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr3_-_156877882 29.235 CCNL1
cyclin L1
chr12_-_123380608 24.120


chr2_-_10588273 23.163 ODC1
ornithine decarboxylase 1
chr3_+_52719935 22.468 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr2_-_10588451 22.314 NM_002539
ODC1
ornithine decarboxylase 1
chr3_+_170075521 19.999 SKIL
SKI-like oncogene
chr3_+_127317271 19.714 MCM2
minichromosome maintenance complex component 2
chr3_+_127317274 19.088 MCM2
minichromosome maintenance complex component 2
chr1_-_245025958 17.991 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr7_+_56019552 17.798 NM_015969
MRPS17
mitochondrial ribosomal protein S17
chr17_-_685385 17.264 NM_016080
GLOD4
glyoxalase domain containing 4
chr19_-_40336944 17.119 FBL
fibrillarin
chr19_-_40337018 15.990 NM_001436
FBL
fibrillarin
chr12_-_76478347 15.969 NAP1L1
nucleosome assembly protein 1-like 1
chr5_+_10353980 15.882


chr22_-_36925270 15.527 NM_003753
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr3_+_127317212 15.173 NM_004526
MCM2
minichromosome maintenance complex component 2
chr22_-_36925212 14.989 EIF3D
eukaryotic translation initiation factor 3, subunit D
chr19_-_40336997 14.881 FBL
fibrillarin
chr19_-_47617008 14.223 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr17_+_57642885 14.130 NM_001166301
NM_024612
DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr1_+_62902735 13.997 USP1
ubiquitin specific peptidase 1
chr16_+_2802683 13.968 SRRM2
serine/arginine repetitive matrix 2
chr12_+_108079516 13.958 NM_007062
PWP1
PWP1 homolog (S. cerevisiae)
chr1_-_186344801 13.936 TPR
translocated promoter region (to activated MET oncogene)
chr2_-_64881040 13.655 NM_014755
SERTAD2
SERTA domain containing 2
chr1_+_52082755 13.617 OSBPL9
oxysterol binding protein-like 9
chr1_+_62902653 13.526 USP1
ubiquitin specific peptidase 1
chr11_+_4116059 13.351 RRM1
ribonucleotide reductase M1
chr12_+_56552141 13.112 MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
chr15_-_91537724 13.098 NM_003981
NM_199413
NM_199414
PRC1


protein regulator of cytokinesis 1


chr3_+_38206968 13.047 NM_005109
OXSR1
oxidative-stress responsive 1
chr4_+_113558119 12.773 NM_016648
LARP7
La ribonucleoprotein domain family, member 7
chr18_+_20513277 12.743 NM_002894
RBBP8
retinoblastoma binding protein 8
chr18_+_57567191 12.735 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr19_+_50180492 12.632 PRMT1
protein arginine methyltransferase 1
chr22_-_41252646 12.606 ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr19_+_13263890 12.561 IER2
immediate early response 2
chr16_+_2802656 12.521 SRRM2
serine/arginine repetitive matrix 2
chr13_+_51484103 12.484 RNASEH2B
ribonuclease H2, subunit B
chr3_-_52312655 12.481 NM_025222
WDR82
WD repeat domain 82
chr5_-_133304274 12.480 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr2_+_242255365 12.418 SEPT2
septin 2
chr11_+_4115923 12.304 NM_001033
RRM1
ribonucleotide reductase M1
chr15_+_66797632 12.195 ZWILCH
Zwilch, kinetochore associated, homolog (Drosophila)
chr17_+_685512 12.173 NM_018146
RNMTL1
RNA methyltransferase like 1
chr22_-_36925138 12.152 EIF3D
eukaryotic translation initiation factor 3, subunit D
chr4_+_146019368 12.107 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr9_-_140083010 11.981 ANAPC2
anaphase promoting complex subunit 2
chr14_-_55369163 11.933 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr12_+_132629014 11.922 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr11_+_4116077 11.820 RRM1
ribonucleotide reductase M1
chr4_-_122744978 11.792 NM_001237
CCNA2
cyclin A2
chr6_-_17706617 11.712 NM_005124
NUP153
nucleoporin 153kDa
chr19_+_50180408 11.675 NM_001207042
NM_001536
NM_198318
PRMT1


protein arginine methyltransferase 1


chr16_+_2802708 11.617 SRRM2
serine/arginine repetitive matrix 2
chr12_-_123380682 11.584 NM_024667
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr12_-_82752154 11.529 NM_014167
CCDC59
coiled-coil domain containing 59
chr11_-_14521328 11.498 COPB1
coatomer protein complex, subunit beta 1
chr12_-_76478410 11.417 NAP1L1
nucleosome assembly protein 1-like 1
chr4_+_144435076 11.398


chr19_-_14529853 11.357 DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr17_+_685606 11.311 RNMTL1
RNA methyltransferase like 1
chr21_-_44527603 11.251 U2AF1
U2 small nuclear RNA auxiliary factor 1
chr2_+_30454396 11.219 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr3_-_185655833 11.167 NM_001243879
NM_004593
TRA2B

transformer 2 beta homolog (Drosophila)

chr1_+_26496382 11.054 NM_015871
ZNF593
zinc finger protein 593
chr13_+_114239047 11.002 NM_007111
TFDP1
transcription factor Dp-1
chr11_+_74660290 10.998 NM_014752
LOC653566
SPCS2
signal peptidase complex subunit 2 homolog pseudogene
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr18_+_2571587 10.949 NDC80
NDC80 kinetochore complex component homolog (S. cerevisiae)
chr16_+_2802634 10.941 SRRM2
serine/arginine repetitive matrix 2
chr1_-_229644077 10.843 NM_018230
NUP133
nucleoporin 133kDa
chr5_+_43121641 10.800 NM_003432
ZNF131
zinc finger protein 131
chr4_-_122744782 10.790 CCNA2
cyclin A2
chr19_+_54694118 10.740 NM_024075
TSEN34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr18_+_2571509 10.736 NM_006101
NDC80
NDC80 kinetochore complex component homolog (S. cerevisiae)
chr17_-_8151373 10.732 NM_025099
CTC1
CTS telomere maintenance complex component 1
chr21_-_44527681 10.727 NM_001025203
NM_001025204
NM_006758
U2AF1


U2 small nuclear RNA auxiliary factor 1


chr4_+_144434555 10.665 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr15_-_23034307 10.645 NIPA2
non imprinted in Prader-Willi/Angelman syndrome 2
chr3_-_25705719 10.613 NM_001068
TOP2B
topoisomerase (DNA) II beta 180kDa
chr15_-_90777144 10.608 CIB1
calcium and integrin binding 1 (calmyrin)
chr8_+_26149004 10.584 NM_002717
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr3_+_133293256 10.551 NM_001134423
CDV3
CDV3 homolog (mouse)
chr11_+_809985 10.535 RPLP2
ribosomal protein, large, P2
chr22_-_41252636 10.530 ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr6_+_36562135 10.523 SRSF3
serine/arginine-rich splicing factor 3
chr11_+_102217947 10.439 NM_001166
BIRC2
baculoviral IAP repeat containing 2
chr17_+_7476023 10.434 NM_001204510
NM_001416
EIF4A1

eukaryotic translation initiation factor 4A1

chr4_+_146019486 10.428 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr3_+_38207247 10.422 OXSR1
oxidative-stress responsive 1
chr11_-_3818971 10.399 NM_005387
NM_016320
NM_139131
NM_139132
NUP98



nucleoporin 98kDa



chr1_-_200638996 10.363 DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr14_+_105219466 10.353 NM_006427
NM_021709
SIVA1

SIVA1, apoptosis-inducing factor

chr12_+_51157636 10.342 NM_005171
ATF1
activating transcription factor 1
chr22_-_36925175 10.333 EIF3D
eukaryotic translation initiation factor 3, subunit D
chr17_-_56084611 10.172 SRSF1
serine/arginine-rich splicing factor 1
chr10_+_70715883 10.152 NM_004728
DDX21
DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
chr8_+_26149043 10.138 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr16_-_2014826 9.930 NM_002952
RPS2
ribosomal protein S2
chr9_-_70490145 9.928 CBWD5
COBW domain containing 5
chr12_+_70636773 9.906 NM_014515
NM_001199302
CNOT2

CCR4-NOT transcription complex, subunit 2

chr11_-_6633400 9.851 TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr11_-_67188614 9.833 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr1_+_171454636 9.783 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chr7_+_107531585 9.757 NM_000108
DLD
dihydrolipoamide dehydrogenase
chr4_-_103748254 9.648 NM_181892
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr19_-_9546154 9.633 NM_006631
NM_198058
ZNF266

zinc finger protein 266

chr9_-_70490106 9.597 CBWD5
CBWD3
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 6
chr1_+_62902708 9.554 USP1
ubiquitin specific peptidase 1
chr9_-_178913 9.544 NM_001145355
NM_001145356
NM_018491
CBWD1


COBW domain containing 1


chr9_-_70490138 9.497 CBWD6
COBW domain containing 6
chr9_-_70490123 9.478 CBWD3
COBW domain containing 3
chr7_-_137686814 9.325 NM_001253775
NM_194071
CREB3L2

cAMP responsive element binding protein 3-like 2

chr16_+_2802673 9.280 SRRM2
serine/arginine repetitive matrix 2
chr5_-_148930912 9.276 CSNK1A1
casein kinase 1, alpha 1
chr4_+_110354927 9.254 NM_001042734
NM_006323
SEC24B

SEC24 family, member B (S. cerevisiae)

chr16_-_67694602 9.235 NM_001082486
NM_001082487
NM_022914
ACD


adrenocortical dysplasia homolog (mouse)


chr17_+_7155371 9.192 NM_203415
NM_015362
NM_203413
NM_203414
C17orf81



chromosome 17 open reading frame 81



chr11_+_74660317 9.104 SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr9_-_70490164 9.085 NM_001024916
NM_201453
CBWD5
CBWD3
COBW domain containing 5
COBW domain containing 3
chr21_-_40720938 9.072 HMGN1
high mobility group nucleosome binding domain 1
chr12_-_123380628 9.051 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr5_+_44808967 9.040 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr17_+_15903107 9.009 TTC19
tetratricopeptide repeat domain 19
chr19_+_36036448 8.995 NM_001242597
NM_001242598
NM_032635
TMEM147


transmembrane protein 147


chr4_+_110354825 8.993 SEC24B
SEC24 family, member B (S. cerevisiae)
chr17_-_2240677 8.975 NM_018128
TSR1
TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
chr14_-_61447711 8.950 NM_020810
TRMT5
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr19_-_8070468 8.919 NM_001419
ELAVL1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr19_-_33166057 8.817 NM_032139
ANKRD27
ankyrin repeat domain 27 (VPS9 domain)
chr6_+_29691203 8.802 HLA-F
major histocompatibility complex, class I, F
chr11_-_14521386 8.772 NM_016451
NM_001144062
NM_001144061
COPB1


coatomer protein complex, subunit beta 1


chr1_-_229643996 8.739 NUP133
nucleoporin 133kDa
chr8_-_131028646 8.738 FAM49B
family with sequence similarity 49, member B
chr11_+_18416111 8.729 LDHA
lactate dehydrogenase A
chr6_-_109703553 8.695 CD164
CD164 molecule, sialomucin
chr7_+_107531618 8.678 DLD
dihydrolipoamide dehydrogenase
chr21_-_44846927 8.669 NM_173354
SIK1
salt-inducible kinase 1
chr8_+_26149080 8.632 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr1_-_35658731 8.626 SFPQ
splicing factor proline/glutamine-rich
chr14_+_50359816 8.626 ARF6
ADP-ribosylation factor 6
chr7_+_107531616 8.626 DLD
dihydrolipoamide dehydrogenase
chr14_+_35452103 8.603 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr14_+_50359829 8.565 ARF6
ADP-ribosylation factor 6
chr9_-_69262517 8.561 NM_001085457
CBWD5
CBWD6
COBW domain containing 5
COBW domain containing 6
chr5_-_32174397 8.530 NM_022130
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr4_-_69215699 8.529 NM_001031732
NM_133370
YTHDC1

YTH domain containing 1

chr6_+_36562139 8.499 SRSF3
serine/arginine-rich splicing factor 3
chr6_-_18264638 8.460 NM_001134709
NM_003472
DEK

DEK oncogene

chr7_-_26240364 8.458 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr5_-_32174385 8.455 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr3_+_128598471 8.453 ACAD9
acyl-CoA dehydrogenase family, member 9
chr7_-_107204336 8.438 COG5
component of oligomeric golgi complex 5
chr9_+_70856838 8.425 NM_201453
CBWD5
CBWD3
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 6
chr1_+_45205533 8.405 KIF2C
kinesin family member 2C
chr6_+_47445440 8.379 NM_012120
CD2AP
CD2-associated protein
chr8_-_131028674 8.369 FAM49B
family with sequence similarity 49, member B
chr11_+_18416106 8.357 LDHA
lactate dehydrogenase A
chr22_-_47134130 8.353 NM_022766
CERK
ceramide kinase
chr11_-_6633178 8.351 TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr11_+_74660321 8.350 SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr1_-_161147209 8.330 B4GALT3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr19_+_59055826 8.305 NM_005762
TRIM28
tripartite motif containing 28
chr1_-_1822501 8.299 GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr14_-_50053068 8.296 NM_001030001
NM_001032
RPS29

ribosomal protein S29

chr12_+_56552044 8.290 NM_021019
NM_079423
MYL6

myosin, light chain 6, alkali, smooth muscle and non-muscle

chr2_+_114195267 8.275 NM_172003
CBWD2
CBWD1
COBW domain containing 2
COBW domain containing 1
chr22_-_29196537 8.226 NM_001079539
NM_005080
XBP1

X-box binding protein 1

chr11_+_117857062 8.217 NM_001558
IL10RA
interleukin 10 receptor, alpha
chr1_+_193028523 8.140 NM_001173524
TROVE2
TROVE domain family, member 2
chr4_+_146019155 8.123 NM_001040876
NM_002940
ABCE1

ATP-binding cassette, sub-family E (OABP), member 1

chr20_-_5107185 8.117 NM_002592
PCNA
proliferating cell nuclear antigen
chr11_-_6633428 8.043 NM_006284
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr14_+_35452194 7.998 SRP54
signal recognition particle 54kDa
chr13_-_31040035 7.976 NM_002128
HMGB1
high mobility group box 1
chr1_+_202976478 7.958 TMEM183B
transmembrane protein 183B
chr5_-_32174355 7.903 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr16_-_46655303 7.896 NM_024745
SHCBP1
SHC SH2-domain binding protein 1
chr16_+_2802605 7.853 SRRM2
serine/arginine repetitive matrix 2
chrX_+_106871739 7.787 PRPS1
phosphoribosyl pyrophosphate synthetase 1
chr4_+_110354971 7.786 SEC24B
SEC24 family, member B (S. cerevisiae)
chr7_-_26240320 7.774 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr17_-_36981552 7.769 NM_017748
CWC25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr11_+_34127110 7.745 NM_001144030
NM_024662
NAT10

N-acetyltransferase 10 (GCN5-related)

chr5_-_133561745 7.733 PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
chr6_+_139456240 7.679 NM_016217
HECA
headcase homolog (Drosophila)
chr1_-_119683210 7.648 NM_015836
NM_201263
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr17_-_73775822 7.646 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr6_-_86352982 7.644 NM_001159677
NM_006372
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chrX_+_106871653 7.628 NM_001204402
NM_002764
PRPS1

phosphoribosyl pyrophosphate synthetase 1

chr1_+_45205466 7.624 NM_006845
KIF2C
kinesin family member 2C
chr16_+_2802640 7.585 SRRM2
serine/arginine repetitive matrix 2
chr7_-_26240366 7.579 NM_002137
NM_031243
HNRNPA2B1

heterogeneous nuclear ribonucleoprotein A2/B1

chr13_-_31039966 7.549 HMGB1
high mobility group box 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.80 1.90e-35 GO:0044260 cellular macromolecule metabolic process
1.58 4.42e-32 GO:0044237 cellular metabolic process
2.03 5.16e-30 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.17 3.80e-29 GO:0090304 nucleic acid metabolic process
1.66 9.17e-29 GO:0043170 macromolecule metabolic process
1.90 7.72e-28 GO:0034641 cellular nitrogen compound metabolic process
1.52 1.23e-26 GO:0044238 primary metabolic process
1.86 2.32e-26 GO:0006807 nitrogen compound metabolic process
2.30 2.36e-26 GO:0016070 RNA metabolic process
2.20 1.74e-24 GO:0010467 gene expression
1.45 2.10e-24 GO:0008152 metabolic process
1.25 1.12e-21 GO:0009987 cellular process
3.08 1.63e-20 GO:0006396 RNA processing
3.79 7.81e-16 GO:0008380 RNA splicing
2.99 1.53e-15 GO:0016071 mRNA metabolic process
3.37 4.31e-15 GO:0006397 mRNA processing
2.49 1.17e-13 GO:0046907 intracellular transport
4.26 1.41e-13 GO:0000375 RNA splicing, via transesterification reactions
1.93 2.64e-13 GO:0009059 macromolecule biosynthetic process
4.27 2.70e-13 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
4.27 2.70e-13 GO:0000398 nuclear mRNA splicing, via spliceosome
1.93 4.52e-13 GO:0034645 cellular macromolecule biosynthetic process
4.95 4.81e-11 GO:0050657 nucleic acid transport
4.95 4.81e-11 GO:0050658 RNA transport
4.95 4.81e-11 GO:0051236 establishment of RNA localization
4.79 1.34e-10 GO:0006403 RNA localization
5.07 1.56e-10 GO:0051028 mRNA transport
2.65 1.61e-10 GO:0044265 cellular macromolecule catabolic process
1.67 2.19e-10 GO:0044249 cellular biosynthetic process
1.64 5.98e-10 GO:0009058 biosynthetic process
4.40 7.52e-10 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.62 2.74e-09 GO:0044267 cellular protein metabolic process
2.41 3.48e-09 GO:0009057 macromolecule catabolic process
1.97 1.53e-08 GO:0051649 establishment of localization in cell
1.94 1.80e-08 GO:0044248 cellular catabolic process
1.55 4.60e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.47 5.17e-08 GO:0071840 cellular component organization or biogenesis
1.75 7.90e-08 GO:0006996 organelle organization
1.86 1.09e-07 GO:0051641 cellular localization
1.96 1.56e-07 GO:0007049 cell cycle
2.10 1.81e-07 GO:0022402 cell cycle process
2.21 1.98e-07 GO:0022403 cell cycle phase
1.82 2.56e-07 GO:0033036 macromolecule localization
2.29 5.62e-07 GO:0000278 mitotic cell cycle
2.40 8.61e-07 GO:0034621 cellular macromolecular complex subunit organization
1.92 2.60e-06 GO:0032774 RNA biosynthetic process
1.72 3.51e-06 GO:0009056 catabolic process
1.43 4.56e-06 GO:0016043 cellular component organization
2.45 6.59e-06 GO:0016032 viral reproduction
1.49 1.37e-05 GO:0071842 cellular component organization at cellular level
2.13 1.60e-05 GO:0051276 chromosome organization
1.44 1.84e-05 GO:0019538 protein metabolic process
3.13 1.93e-05 GO:0022613 ribonucleoprotein complex biogenesis
2.59 2.19e-05 GO:0043632 modification-dependent macromolecule catabolic process
2.55 5.35e-05 GO:0019941 modification-dependent protein catabolic process
1.88 6.34e-05 GO:0045184 establishment of protein localization
2.44 6.57e-05 GO:0034622 cellular macromolecular complex assembly
2.97 7.03e-05 GO:0071843 cellular component biogenesis at cellular level
2.54 8.78e-05 GO:0006511 ubiquitin-dependent protein catabolic process
2.29 9.10e-05 GO:0000279 M phase
2.48 1.14e-04 GO:0051603 proteolysis involved in cellular protein catabolic process
1.88 1.17e-04 GO:0043933 macromolecular complex subunit organization
1.87 1.28e-04 GO:0015031 protein transport
4.70 1.39e-04 GO:0006405 RNA export from nucleus
1.85 1.65e-04 GO:0006351 transcription, DNA-dependent
1.87 1.85e-04 GO:0033554 cellular response to stress
2.44 1.98e-04 GO:0044257 cellular protein catabolic process
3.47 3.32e-04 GO:0042254 ribosome biogenesis
2.48 3.44e-04 GO:0006412 translation
3.01 3.74e-04 GO:0006913 nucleocytoplasmic transport
2.58 3.95e-04 GO:0034660 ncRNA metabolic process
4.64 4.18e-04 GO:0031124 mRNA 3'-end processing
2.97 4.80e-04 GO:0051169 nuclear transport
2.33 4.88e-04 GO:0030163 protein catabolic process
2.47 5.61e-04 GO:0000087 M phase of mitotic cell cycle
3.58 6.51e-04 GO:0006401 RNA catabolic process
4.01 7.93e-04 GO:0051168 nuclear export
2.46 9.14e-04 GO:0006366 transcription from RNA polymerase II promoter
4.64 9.91e-04 GO:0006406 mRNA export from nucleus
1.67 1.03e-03 GO:0044085 cellular component biogenesis
1.66 1.33e-03 GO:0031325 positive regulation of cellular metabolic process
3.18 1.68e-03 GO:0048193 Golgi vesicle transport
1.68 1.76e-03 GO:0051246 regulation of protein metabolic process
1.68 1.94e-03 GO:0008104 protein localization
1.35 1.97e-03 GO:0060255 regulation of macromolecule metabolic process
2.41 2.13e-03 GO:0000280 nuclear division
2.41 2.13e-03 GO:0007067 mitosis
2.45 2.74e-03 GO:0007346 regulation of mitotic cell cycle
1.90 3.75e-03 GO:0051726 regulation of cell cycle
1.84 3.86e-03 GO:0065003 macromolecular complex assembly
2.33 4.61e-03 GO:0048285 organelle fission
3.90 5.24e-03 GO:0031123 RNA 3'-end processing
1.32 5.58e-03 GO:0031323 regulation of cellular metabolic process
1.67 5.72e-03 GO:0032268 regulation of cellular protein metabolic process
1.40 5.86e-03 GO:0048522 positive regulation of cellular process
1.32 6.31e-03 GO:0080090 regulation of primary metabolic process
2.23 7.05e-03 GO:0070647 protein modification by small protein conjugation or removal
1.62 7.40e-03 GO:0010604 positive regulation of macromolecule metabolic process
3.79 7.56e-03 GO:0000956 nuclear-transcribed mRNA catabolic process
1.58 9.19e-03 GO:0009893 positive regulation of metabolic process
3.53 1.08e-02 GO:0006364 rRNA processing
5.15 1.13e-02 GO:0006888 ER to Golgi vesicle-mediated transport
2.77 1.21e-02 GO:0006417 regulation of translation
2.33 1.26e-02 GO:0010608 posttranscriptional regulation of gene expression
1.28 1.60e-02 GO:0019222 regulation of metabolic process
2.15 1.73e-02 GO:0010564 regulation of cell cycle process
3.52 2.10e-02 GO:0006402 mRNA catabolic process
3.10 2.25e-02 GO:0071824 protein-DNA complex subunit organization
3.34 2.35e-02 GO:0016072 rRNA metabolic process
1.43 2.40e-02 GO:0043412 macromolecule modification
4.78 2.48e-02 GO:0006369 termination of RNA polymerase II transcription
2.21 2.82e-02 GO:0051329 interphase of mitotic cell cycle
2.84 3.15e-02 GO:0006333 chromatin assembly or disassembly
3.10 3.76e-02 GO:0065004 protein-DNA complex assembly
2.17 4.10e-02 GO:0051325 interphase
2.71 4.15e-02 GO:0071103 DNA conformation change
2.42 4.39e-02 GO:0000075 cell cycle checkpoint
2.02 4.48e-02 GO:0006886 intracellular protein transport
2.51 4.66e-02 GO:0034470 ncRNA processing

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.34 6.24e-39 GO:0044428 nuclear part
1.44 1.31e-38 GO:0043231 intracellular membrane-bounded organelle
1.43 2.04e-38 GO:0043227 membrane-bounded organelle
1.67 8.25e-38 GO:0044446 intracellular organelle part
1.66 3.61e-37 GO:0044422 organelle part
1.30 9.27e-37 GO:0044424 intracellular part
1.28 3.20e-35 GO:0005622 intracellular
2.35 2.26e-32 GO:0031981 nuclear lumen
2.15 7.25e-31 GO:0070013 intracellular organelle lumen
1.34 1.09e-29 GO:0043229 intracellular organelle
2.10 1.31e-29 GO:0031974 membrane-enclosed lumen
2.11 1.85e-29 GO:0043233 organelle lumen
1.34 2.18e-29 GO:0043226 organelle
1.58 1.44e-28 GO:0005634 nucleus
2.44 4.25e-25 GO:0005654 nucleoplasm
1.74 9.47e-24 GO:0032991 macromolecular complex
1.33 2.90e-19 GO:0005737 cytoplasm
1.40 2.06e-15 GO:0044444 cytoplasmic part
1.83 5.89e-15 GO:0005829 cytosol
2.80 1.61e-13 GO:0030529 ribonucleoprotein complex
1.58 1.59e-11 GO:0043234 protein complex
2.56 5.01e-10 GO:0005730 nucleolus
3.95 6.01e-08 GO:0005681 spliceosomal complex
2.27 2.26e-07 GO:0005694 chromosome
1.56 8.55e-07 GO:0031090 organelle membrane
4.62 2.43e-06 GO:0071013 catalytic step 2 spliceosome
1.99 4.39e-06 GO:0044451 nucleoplasm part
2.00 5.26e-06 GO:0031967 organelle envelope
1.45 7.65e-06 GO:0043228 non-membrane-bounded organelle
1.45 7.65e-06 GO:0043232 intracellular non-membrane-bounded organelle
2.25 8.98e-06 GO:0044427 chromosomal part
1.96 1.10e-05 GO:0031975 envelope
1.07 1.98e-05 GO:0044464 cell part
1.07 2.04e-05 GO:0005623 cell
9.13 5.33e-05 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.67 1.57e-04 GO:0016604 nuclear body
1.55 2.11e-04 GO:0012505 endomembrane system
2.49 7.62e-04 GO:0005635 nuclear envelope
2.89 2.71e-03 GO:0000793 condensed chromosome
3.32 8.24e-03 GO:0000776 kinetochore
1.72 1.12e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network
2.89 1.12e-02 GO:0016607 nuclear speck
2.70 1.25e-02 GO:0000775 chromosome, centromeric region
1.54 1.65e-02 GO:0005783 endoplasmic reticulum
1.70 2.00e-02 GO:0005789 endoplasmic reticulum membrane
2.41 2.40e-02 GO:0005840 ribosome
2.59 3.48e-02 GO:0031965 nuclear membrane
5.04 4.80e-02 GO:0000152 nuclear ubiquitin ligase complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.42 6.57e-24 GO:0005515 protein binding
2.58 1.12e-17 GO:0003723 RNA binding
1.18 4.89e-15 GO:0005488 binding
1.71 1.94e-12 GO:0000166 nucleotide binding
1.53 3.56e-11 GO:0003676 nucleic acid binding
1.65 6.40e-08 GO:0035639 purine ribonucleoside triphosphate binding
1.62 1.80e-07 GO:0017076 purine nucleotide binding
1.62 2.18e-07 GO:0032553 ribonucleotide binding
1.62 2.18e-07 GO:0032555 purine ribonucleotide binding
1.64 7.86e-06 GO:0005524 ATP binding
1.62 1.48e-05 GO:0030554 adenyl nucleotide binding
1.61 1.93e-05 GO:0032559 adenyl ribonucleotide binding
2.23 7.28e-04 GO:0016887 ATPase activity
3.34 1.76e-03 GO:0008026 ATP-dependent helicase activity
3.34 1.76e-03 GO:0070035 purine NTP-dependent helicase activity
5.15 2.73e-03 GO:0019783 small conjugating protein-specific protease activity
2.93 2.83e-03 GO:0004386 helicase activity
5.87 6.10e-03 GO:0003727 single-stranded RNA binding
1.22 6.81e-03 GO:0003824 catalytic activity
3.96 9.24e-03 GO:0004221 ubiquitin thiolesterase activity
1.67 1.23e-02 GO:0016462 pyrophosphatase activity
1.68 1.29e-02 GO:0017111 nucleoside-triphosphatase activity
1.67 1.39e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.66 1.58e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
2.17 1.70e-02 GO:0042623 ATPase activity, coupled
3.84 2.62e-02 GO:0003697 single-stranded DNA binding
4.70 4.41e-02 GO:0004843 ubiquitin-specific protease activity
1.83 4.77e-02 GO:0016874 ligase activity