Motif ID: EBF1.p2

Z-value: 1.937


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1



Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_170102098 48.115 NM_001202550
NM_182552
WDR27

WD repeat domain 27

chr11_+_73359734 24.647 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr11_-_117747331 24.072 FXYD6
FXYD domain containing ion transport regulator 6
chr11_-_117747618 20.071 NM_001204268
NM_001243598
NM_001164832
NM_001164836
NM_001164837
NM_022003
FXYD6-FXYD2

FXYD6



FXYD6-FXYD2 readthrough

FXYD domain containing ion transport regulator 6



chr8_-_22089517 19.836 PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr2_+_17935379 18.749 NM_001130009
GEN1
Gen endonuclease homolog 1 (Drosophila)
chr8_-_22089850 18.419 NM_001099335
NM_014759
PHYHIP

phytanoyl-CoA 2-hydroxylase interacting protein

chr4_+_4388804 17.541 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr16_+_22825481 17.361 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr4_+_128651518 17.324 NM_031291
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr1_+_2005424 17.294 NM_001242874
PRKCZ
protein kinase C, zeta
chr4_+_4388717 17.212 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr16_+_58498216 16.921 NDRG4
NDRG family member 4
chr14_+_92790151 16.597 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr19_+_50936159 16.133 NM_004533
MYBPC2
myosin binding protein C, fast type
chr16_+_58534045 16.101 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr13_-_30881556 14.715 NM_032116
KATNAL1
katanin p60 subunit A-like 1
chr1_+_152647770 14.586 NM_178429
LCE2C
late cornified envelope 2C
chr16_-_19896105 14.537 NM_016235
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr8_-_33424642 14.049 NM_024787
RNF122
ring finger protein 122
chr16_+_2039945 13.403 NM_004209
SYNGR3
synaptogyrin 3
chr11_+_69924407 13.382 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr13_+_113623496 13.146 NM_001112732
MCF2L
MCF.2 cell line derived transforming sequence-like
chr18_+_11981457 13.116 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr4_+_4387982 13.002 NM_001040101
NM_014392
D4S234E

DNA segment on chromosome 4 (unique) 234 expressed sequence

chr10_-_46970595 12.884 NM_031912
NM_181519
SYT15

synaptotagmin XV

chr22_+_21986968 12.850 NM_152612
CCDC116
coiled-coil domain containing 116
chr8_+_104152876 12.753 NM_001024372
NM_024812
BAALC

brain and acute leukemia, cytoplasmic

chr6_+_42531767 12.745 UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_-_156217717 12.581 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr2_+_17935124 12.575 NM_182625
GEN1
Gen endonuclease homolog 1 (Drosophila)
chr1_-_203154304 12.383 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr3_-_49907304 12.184 NM_024046
CAMKV
CaM kinase-like vesicle-associated
chr17_-_10101854 12.149 NM_201433
GAS7
growth arrest-specific 7
chr19_-_38720312 11.936 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr19_-_5680910 11.727 NM_205767
C19orf70
chromosome 19 open reading frame 70
chr3_-_183543295 11.691 NM_024871
MAP6D1
MAP6 domain containing 1
chr7_-_994259 11.645 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chr10_-_73848263 11.548 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr16_+_30418576 11.465 NM_001142305
NM_016643
ZNF771

zinc finger protein 771

chr16_+_22825806 11.346 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr3_+_93698959 11.186 NM_001174150
NM_001174151
NM_144996
NM_182896
ARL13B



ADP-ribosylation factor-like 13B



chr1_+_1550794 11.114 NM_001170686
NM_001170687
NM_001170688
NM_080875
MIB2



mindbomb homolog 2 (Drosophila)



chr8_-_99306563 11.084 NM_024759
NIPAL2
NIPA-like domain containing 2
chr6_+_71123147 11.030 FAM135A
family with sequence similarity 135, member A
chr4_-_657424 10.989


chr5_-_79286793 10.940 NM_001010891
NM_001167741
MTX3

metaxin 3

chr17_+_44068828 10.929 MAPT
microtubule-associated protein tau
chr16_-_3184858 10.848


chr17_-_8093346 10.842 C17orf59
chromosome 17 open reading frame 59
chr2_+_113816684 10.680 NM_012275
IL36RN
interleukin 36 receptor antagonist
chr1_-_1051458 10.383 C1orf159
chromosome 1 open reading frame 159
chr3_+_101443436 10.237 NM_024548
CEP97
centrosomal protein 97kDa
chr3_-_38071030 10.171 NM_006225
PLCD1
phospholipase C, delta 1
chr1_+_77747727 10.141 AK5
adenylate kinase 5
chr20_+_58515408 10.133 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr1_+_77747602 10.120 NM_174858
AK5
adenylate kinase 5
chr19_+_54024176 10.086 NM_018555
ZNF331
zinc finger protein 331
chr3_-_195306274 10.005 APOD
apolipoprotein D
chr19_-_6502224 9.974 NM_006087
TUBB4A
tubulin, beta 4A class IVa
chr1_+_154301219 9.805 ATP8B2
ATPase, class I, type 8B, member 2
chr8_+_42128821 9.741 IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr14_-_94844881 9.733 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr19_-_9731883 9.732 NM_152289
ZNF561
zinc finger protein 561
chr8_+_42128834 9.555 IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr15_+_75118950 9.554 NM_001030005
CPLX3
complexin 3
chr2_+_219724545 9.423 NM_006522
WNT6
wingless-type MMTV integration site family, member 6
chr1_-_182360400 9.367 NM_001033056
GLUL
glutamate-ammonia ligase
chr17_-_36956145 9.323 NM_003559
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr6_-_46459010 9.197 NM_001251974
RCAN2
regulator of calcineurin 2
chr16_+_89724175 9.112 NM_153025
C16orf55
chromosome 16 open reading frame 55
chr1_-_113162215 9.045 ST7L
suppression of tumorigenicity 7 like
chr8_-_110620220 9.008 SYBU
syntabulin (syntaxin-interacting)
chr16_+_30418885 8.972 ZNF771
zinc finger protein 771
chr15_+_40886442 8.915 NM_144508
NM_170589
CASC5

cancer susceptibility candidate 5

chr1_-_85725315 8.909 NM_198077
C1orf52
chromosome 1 open reading frame 52
chr5_-_851100 8.716 NM_024786
ZDHHC11
zinc finger, DHHC-type containing 11
chr12_-_48152860 8.708 NM_001098531
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr16_+_58497548 8.703 NM_020465
NDRG4
NDRG family member 4
chr7_-_98467483 8.698 TMEM130
transmembrane protein 130
chr1_+_1981902 8.686 NM_002744
PRKCZ
protein kinase C, zeta
chr8_+_141521365 8.658 NM_017444
CHRAC1
chromatin accessibility complex 1
chr6_+_71123105 8.611 NM_001105531
NM_020819
FAM135A

family with sequence similarity 135, member A

chr8_+_1952875 8.491 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr17_+_79609298 8.476 NM_031945
TSPAN10
tetraspanin 10
chr16_+_1386197 8.473 NM_001199096
BAIAP3
BAI1-associated protein 3
chr3_-_9834357 8.468 NM_006354
NM_133480
TADA3

transcriptional adaptor 3

chr12_+_119616594 8.403 NM_014365
HSPB8
heat shock 22kDa protein 8
chr7_-_124405029 8.379 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr6_-_32551993 8.373 HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr12_+_53443834 8.346 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr19_-_2236648 8.322 PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr1_-_49242406 8.318 NM_024603
BEND5
BEN domain containing 5
chr17_-_8093492 8.316 NM_017622
C17orf59
chromosome 17 open reading frame 59
chr16_+_58497628 8.309 NDRG4
NDRG family member 4
chr1_-_67390413 8.293 NM_024763
NM_207014
WDR78

WD repeat domain 78

chr2_-_97523626 8.191 NM_016466
ANKRD39
ankyrin repeat domain 39
chr1_-_42630386 8.165 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr1_+_2005083 8.162 NM_001033581
PRKCZ
protein kinase C, zeta
chr19_+_49622480 8.133 NM_003660
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr1_+_36023389 8.103 NM_001014839
NM_001014841
NM_014284
NCDN


neurochondrin


chr8_+_11142314 8.102 MTMR9
myotubularin related protein 9
chr17_+_79633724 8.082 NM_199287
CCDC137
coiled-coil domain containing 137
chr8_+_142138684 7.983 NM_014957
DENND3
DENN/MADD domain containing 3
chr22_-_36013303 7.940 NM_005368
NM_203378
MB

myoglobin

chr15_+_32933869 7.889 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr15_-_40987284 7.824 LOC100505648
uncharacterized LOC100505648
chr6_+_7590405 7.824 NM_152551
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr14_+_76127592 7.809 TTLL5
tubulin tyrosine ligase-like family, member 5
chr16_-_30546145 7.774 NM_023931
ZNF747
zinc finger protein 747
chr14_-_77787023 7.707 NM_013382
POMT2
protein-O-mannosyltransferase 2
chr11_-_62369097 7.702 MTA2
metastasis associated 1 family, member 2
chr19_+_48867650 7.692 NM_012451
SYNGR4
synaptogyrin 4
chr17_+_38119225 7.688 NM_178171
GSDMA
gasdermin A
chr15_-_45670955 7.582 NM_001482
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr7_-_142583260 7.576 NM_018646
TRPV6
transient receptor potential cation channel, subfamily V, member 6
chr15_+_75639330 7.572 NM_024608
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr17_-_48207113 7.557 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr18_+_51795848 7.514 NM_007195
POLI
polymerase (DNA directed) iota
chr7_-_994008 7.478 ADAP1
ArfGAP with dual PH domains 1
chr7_-_4923246 7.433 NM_018059
RADIL
Ras association and DIL domains
chr19_+_12949258 7.432 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr1_-_182360889 7.429 GLUL
glutamate-ammonia ligase
chr1_+_156339002 7.418 NM_020407
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr22_-_18484183 7.396 MICAL3
microtubule associated monoxygenase, calponin and LIM domain containing 3
chr17_+_78194090 7.387 NM_001166347
NM_001166348
NM_001166349
NM_173626
SLC26A11



solute carrier family 26, member 11



chr3_+_9834201 7.373 NM_001198793
NM_005718
ARPC4-TTLL3
ARPC4
ARPC4-TTLL3 readthrough
actin related protein 2/3 complex, subunit 4, 20kDa
chr3_+_130745693 7.371 NM_001146003
NM_024800
NM_145910
NEK11


NIMA (never in mitosis gene a)- related kinase 11


chr19_-_51327003 7.366 NM_002257
KLK1
kallikrein 1
chr2_+_131674223 7.362 NM_015320
NM_032995
ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4

chr9_-_136150629 7.324 NM_020469
ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr5_-_149792276 7.288 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr15_+_85144219 7.249 NM_001007072
NM_017894
NM_181877
ZSCAN2


zinc finger and SCAN domain containing 2


chr19_+_56652689 7.215 ZNF444
zinc finger protein 444
chr15_-_45670624 7.185 GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr22_-_39240016 7.110 NM_014293
NPTXR
neuronal pentraxin receptor
chr17_-_34890610 7.110 MYO19
myosin XIX
chr3_+_23987514 7.105 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr15_+_62682682 7.061 TLN2
talin 2
chr16_-_1525006 7.023 CLCN7
chloride channel 7
chr8_-_144241725 7.023 NM_001135655
LY6H
lymphocyte antigen 6 complex, locus H
chr17_+_8339135 7.007 NM_001025579
NM_030808
NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

chr8_-_144241456 7.004 NM_002347
LY6H
lymphocyte antigen 6 complex, locus H
chr2_-_9695827 6.985 ADAM17
ADAM metallopeptidase domain 17
chr9_-_101470836 6.941 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr18_+_55711746 6.936 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr5_-_149792370 6.920 NM_001025158
NM_001025159
NM_004355
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr19_+_47524142 6.912 NM_002517
NPAS1
neuronal PAS domain protein 1
chr16_-_4588379 6.832 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr1_-_16345284 6.782 NM_014424
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr19_+_56652529 6.773 NM_001253792
NM_018337
ZNF444

zinc finger protein 444

chr17_-_79105747 6.745 NM_004920
AATK
apoptosis-associated tyrosine kinase
chr9_-_136150604 6.740 ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr8_-_21966812 6.739 NM_024815
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr1_-_151118932 6.688 NM_001178061
NM_001178062
NM_030913
SEMA6C


sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C


chr5_-_141257943 6.676 NM_002587
NM_032420
PCDH1

protocadherin 1

chr11_+_118401873 6.628 TMEM25
transmembrane protein 25
chr1_-_182360181 6.620 GLUL
glutamate-ammonia ligase
chr11_-_62368921 6.612 MTA2
metastasis associated 1 family, member 2
chr1_-_113161724 6.597 NM_017744
NM_138727
NM_138728
NM_138729
ST7L



suppression of tumorigenicity 7 like



chr11_+_63993720 6.593 NM_001128612
NM_001128613
NM_032344
NUDT22


nudix (nucleoside diphosphate linked moiety X)-type motif 22


chr1_-_27998658 6.526 IFI6
interferon, alpha-inducible protein 6
chr12_+_79258588 6.457 SYT1
synaptotagmin I
chr15_-_64648359 6.441 NM_022048
CSNK1G1
casein kinase 1, gamma 1
chr19_-_57183122 6.431 NM_001005850
ZNF835
zinc finger protein 835
chr4_+_47033294 6.413 NM_000812
GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr21_+_27107322 6.400 NM_002040
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr1_-_236445084 6.359 ERO1LB
ERO1-like beta (S. cerevisiae)
chr17_+_27055797 6.358 NM_178170
NEK8
NIMA (never in mitosis gene a)- related kinase 8
chr4_-_90758126 6.355 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr16_-_4588738 6.353 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr19_-_14016908 6.341 NM_024323
C19orf57
chromosome 19 open reading frame 57
chr19_+_47813074 6.320 NM_001736
C5AR1
complement component 5a receptor 1
chrX_+_102470003 6.307 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr6_-_168197525 6.288 C6orf123
chromosome 6 open reading frame 123
chrY_-_15591799 6.286 UTY
ubiquitously transcribed tetratricopeptide repeat gene, Y-linked
chr7_+_154002194 6.269 NM_001936
DPP6
dipeptidyl-peptidase 6
chr3_+_186560462 6.258 NM_001177800
NM_004797
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr2_+_120770602 6.251 NM_001184937
NM_001184939
NM_020909
EPB41L5


erythrocyte membrane protein band 4.1 like 5


chr1_-_161279724 6.229 NM_000530
MPZ
myelin protein zero
chrX_+_48660286 6.220 HDAC6
histone deacetylase 6
chr7_-_102715171 6.191 NM_001111038
FBXL13
F-box and leucine-rich repeat protein 13
chr13_+_113622758 6.187 MCF2L
MCF.2 cell line derived transforming sequence-like
chr17_+_34958018 6.160 NM_024864
MRM1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr5_-_32444729 6.152 ZFR
zinc finger RNA binding protein
chr17_+_79604196 6.141 TSPAN10
tetraspanin 10
chr13_-_37494370 6.141 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr19_-_6279797 6.131


chr17_-_42992852 6.129 NM_001131019
NM_001242376
NM_002055
GFAP


glial fibrillary acidic protein


chr19_-_39390168 6.123 NM_012237
NM_001193286
NM_030593
SIRT2


sirtuin 2


chr22_+_30752612 6.119 NM_001017437
CCDC157
coiled-coil domain containing 157
chr19_+_38042275 6.103 NM_152606
LOC100507433
ZNF540
uncharacterized LOC100507433
zinc finger protein 540
chr19_+_18794487 6.088 CRTC1
CREB regulated transcription coactivator 1
chr4_-_5890142 6.072 CRMP1
collapsin response mediator protein 1
chr9_-_114361904 6.071 PTGR1
prostaglandin reductase 1
chr22_+_23229959 6.071 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr10_+_104678001 6.069 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr20_+_44650260 6.026 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr17_-_18585571 5.973 NM_001145045
ZNF286B
zinc finger protein 286B
chr3_-_69435429 5.972 NM_015123
FRMD4B
FERM domain containing 4B

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 1.63e-15 GO:0023052 signaling
1.22 4.15e-15 GO:0065007 biological regulation
1.21 3.36e-12 GO:0050789 regulation of biological process
1.36 4.16e-11 GO:0007165 signal transduction
1.31 5.91e-11 GO:0051716 cellular response to stimulus
1.23 1.88e-10 GO:0050896 response to stimulus
1.20 4.43e-10 GO:0050794 regulation of cellular process
1.41 1.56e-08 GO:0042221 response to chemical stimulus
1.11 7.87e-08 GO:0009987 cellular process
1.42 1.11e-06 GO:0007166 cell surface receptor linked signaling pathway
1.21 4.87e-06 GO:0032501 multicellular organismal process
1.86 1.23e-05 GO:0007268 synaptic transmission
1.37 4.22e-05 GO:0048583 regulation of response to stimulus
1.75 1.11e-04 GO:0019226 transmission of nerve impulse
1.75 1.11e-04 GO:0035637 multicellular organismal signaling
1.38 1.52e-04 GO:0023051 regulation of signaling
1.58 1.91e-04 GO:0007267 cell-cell signaling
1.22 6.26e-04 GO:0032502 developmental process
1.47 9.61e-04 GO:0007154 cell communication
1.51 1.23e-03 GO:0040011 locomotion
1.38 1.57e-03 GO:0009966 regulation of signal transduction
1.29 3.05e-03 GO:0065008 regulation of biological quality
1.22 3.20e-03 GO:0007275 multicellular organismal development
1.76 1.30e-02 GO:0044057 regulation of system process
2.37 1.96e-02 GO:0006836 neurotransmitter transport
2.78 2.53e-02 GO:0007269 neurotransmitter secretion
1.36 2.64e-02 GO:0010033 response to organic substance

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.48 3.05e-13 GO:0044459 plasma membrane part
1.47 1.57e-06 GO:0031226 intrinsic to plasma membrane
1.47 2.38e-06 GO:0005887 integral to plasma membrane
2.05 3.23e-04 GO:0030141 stored secretory granule
1.19 4.28e-04 GO:0005886 plasma membrane
1.19 4.44e-04 GO:0071944 cell periphery
1.39 1.42e-03 GO:0000267 cell fraction
2.74 4.78e-03 GO:0031256 leading edge membrane
1.82 8.26e-03 GO:0016323 basolateral plasma membrane
3.04 1.27e-02 GO:0030173 integral to Golgi membrane
1.49 1.29e-02 GO:0030054 cell junction
2.10 1.45e-02 GO:0031253 cell projection membrane
1.98 1.54e-02 GO:0031300 intrinsic to organelle membrane
2.06 1.81e-02 GO:0031301 integral to organelle membrane
1.12 1.94e-02 GO:0044425 membrane part
1.10 2.93e-02 GO:0016020 membrane
4.77 3.09e-02 GO:0042613 MHC class II protein complex
2.84 3.23e-02 GO:0031228 intrinsic to Golgi membrane
1.51 4.42e-02 GO:0000139 Golgi membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.08 5.06e-05 GO:0005488 binding
2.26 1.52e-04 GO:0005085 guanyl-nucleotide exchange factor activity
1.74 2.64e-04 GO:0015267 channel activity
1.73 2.95e-04 GO:0022803 passive transmembrane transporter activity
1.68 2.14e-03 GO:0022838 substrate-specific channel activity
1.43 2.61e-03 GO:0022857 transmembrane transporter activity
1.67 4.27e-03 GO:0005216 ion channel activity
3.34 5.51e-03 GO:0003823 antigen binding
1.77 1.18e-02 GO:0005261 cation channel activity
1.35 1.19e-02 GO:0005215 transporter activity
1.11 2.60e-02 GO:0005515 protein binding
1.39 3.32e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.54 3.59e-02 GO:0030695 GTPase regulator activity
2.29 4.07e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.66 4.16e-02 GO:0022836 gated channel activity
1.35 4.65e-02 GO:0022892 substrate-specific transporter activity
2.07 4.78e-02 GO:0015276 ligand-gated ion channel activity
2.07 4.78e-02 GO:0022834 ligand-gated channel activity