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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: EGR1..3.p2

Z-value: 2.377

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_+_124609775	43.717	NM_001126181 NM_006176	NRGN	neurogranin (protein kinase C substrate, RC3)
chr11_+_124609841	35.086		NRGN	neurogranin (protein kinase C substrate, RC3)
chr6_-_46459010	34.654	NM_001251974	RCAN2	regulator of calcineurin 2
chr1_+_6845381	33.173	NM_001195563 NM_001242701 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chrX_-_47479229	28.142	NM_006950 NM_133499	SYN1	synapsin I
chr10_-_75255718	27.699		PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme
chr12_+_79258517	24.640		SYT1	synaptotagmin I
chr20_-_50384861	24.146		ATP9A	ATPase, class II, type 9A
chr12_+_79258588	23.089		SYT1	synaptotagmin I
chr11_-_236833	23.088		SIRT3	sirtuin 3
chr4_-_102267952	23.060		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr14_+_29236882	22.683		FOXG1	forkhead box G1
chr20_-_62130390	22.563	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr7_-_44365019	21.273	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr12_+_79258794	20.671		SYT1	synaptotagmin I
chr7_+_55955129	20.080		ZNF713	zinc finger protein 713
chr7_+_64498643	19.747		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr16_-_19896105	19.267	NM_016235	GPRC5B	G protein-coupled receptor, family C, group 5, member B
chr7_-_51384458	18.727	NM_015198	COBL	cordon-bleu homolog (mouse)
chr20_+_10199455	18.121	NM_003081 NM_130811	SNAP25	synaptosomal-associated protein, 25kDa
chr14_+_100150596	17.821	NM_006668	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1
chr12_+_79258448	17.613	NM_005639	SYT1	synaptotagmin I
chr20_+_44035203	17.480	NM_001048223 NM_001048224	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr7_-_32931409	17.462	NM_015483	KBTBD2	kelch repeat and BTB (POZ) domain containing 2
chr20_-_50384899	17.424	NM_006045	ATP9A	ATPase, class II, type 9A
chr20_+_44034632	17.169	NM_001197139 NM_001048221 NM_001048222 NM_001197140 NM_018478	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr12_-_124457099	17.134	NM_025140	CCDC92	coiled-coil domain containing 92
chr3_+_50712671	16.825	NM_004947	DOCK3	dedicator of cytokinesis 3
chr12_-_96793797	16.742		CDK17	cyclin-dependent kinase 17
chr4_-_102268626	15.509	NM_000944 NM_001130691 NM_001130692	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr7_+_65338161	15.507	NM_173517	VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr15_-_73925555	15.304		NPTN	neuroplastin
chr1_-_154193044	14.807		C1orf43	chromosome 1 open reading frame 43
chrX_+_101380659	14.451	NM_080390	TCEAL2	transcription elongation factor A (SII)-like 2
chr1_+_77747602	14.354	NM_174858	AK5	adenylate kinase 5
chr14_-_23821423	14.353	NM_020372	SLC22A17	solute carrier family 22, member 17
chr22_+_19701968	14.214	NM_002688	SEPT5	septin 5
chr11_-_134281725	14.120	NM_018644 NM_054025	B3GAT1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr19_+_708766	14.030	NM_001040134 NM_002579	PALM	paralemmin
chr17_-_8066254	14.008	NM_014232	VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr12_-_106532447	13.734		NUAK1	NUAK family, SNF1-like kinase, 1
chr6_-_35656610	13.659		FKBP5	FK506 binding protein 5
chr1_-_9189087	13.362	NM_024980	GPR157	G protein-coupled receptor 157
chr20_+_17207669	13.257		PCSK2	proprotein convertase subtilisin/kexin type 2
chrX_+_47092362	12.989		USP11	ubiquitin specific peptidase 11
chr4_-_102268333	12.572		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr16_+_56225301	12.529		GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr17_-_74236272	12.450	NM_052916	RNF157	ring finger protein 157
chr14_-_23822025	12.412	NM_016609	SLC22A17	solute carrier family 22, member 17
chr1_+_38259458	12.226	NM_001031740 NM_001113482	MANEAL	mannosidase, endo-alpha-like
chr9_-_139907614	12.163		ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr20_+_34742656	12.084	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr5_+_139493689	12.062	NM_005859	PURA	purine-rich element binding protein A
chr4_-_5890142	12.026		CRMP1	collapsin response mediator protein 1
chr7_-_150945731	11.953	NM_001003801	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr16_-_402617	11.947	NM_003502 NM_181050	AXIN1	axin 1
chr7_-_108096693	11.760	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chr9_+_137979513	11.684		OLFM1	olfactomedin 1
chr6_-_84418705	11.536	NM_001242792	SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr19_+_18208596	11.525	NM_015016	MAST3	microtubule associated serine/threonine kinase 3
chr14_-_21493910	11.424	NM_016250 NM_201535 NM_201536 NM_201537	NDRG2	NDRG family member 2
chr13_+_98086681	11.332		RAP2A	RAP2A, member of RAS oncogene family
chr15_-_72410226	11.330	NM_006901	MYO9A	myosin IXA
chr13_-_45150391	11.293		TSC22D1	TSC22 domain family, member 1
chr20_-_61569227	11.292		DIDO1	death inducer-obliterator 1
chr9_+_17578952	11.276	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr2_+_10183630	11.243	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr11_-_12030838	11.091		DKK3	dickkopf 3 homolog (Xenopus laevis)
chr1_-_20812727	11.087	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr15_-_72410108	11.076		MYO9A	myosin IXA
chr6_-_110500803	11.072		WASF1	WAS protein family, member 1
chr17_-_1083008	11.055	NM_021962	ABR	active BCR-related gene
chr10_-_15413054	10.989	NM_001010924	FAM171A1	family with sequence similarity 171, member A1
chr17_+_79008958	10.979		BAIAP2	BAI1-associated protein 2
chr17_-_79008372	10.922		FLJ90757	uncharacterized LOC440465
chr16_+_84178864	10.898	NM_178452	DNAAF1	dynein, axonemal, assembly factor 1
chr19_+_35634153	10.869	NM_022006	FXYD7	FXYD domain containing ion transport regulator 7
chr3_-_49907304	10.865	NM_024046	CAMKV	CaM kinase-like vesicle-associated
chr16_+_84002099	10.858	NM_019065	NECAB2	N-terminal EF-hand calcium binding protein 2
chr19_-_42498320	10.854	NM_152296	ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr9_-_13279562	10.813		MPDZ	multiple PDZ domain protein
chr5_+_172483285	10.784	NM_001168393 NM_001168394 NM_153607	C5orf41	chromosome 5 open reading frame 41
chr11_-_12030882	10.751	NM_013253	DKK3	dickkopf 3 homolog (Xenopus laevis)
chr17_+_79008945	10.683	NM_001144888 NM_006340 NM_017450 NM_017451	BAIAP2	BAI1-associated protein 2
chr7_+_102715580	10.539		ARMC10	armadillo repeat containing 10
chr11_-_12030539	10.529		DKK3	dickkopf 3 homolog (Xenopus laevis)
chr7_+_35840595	10.482	NM_001011553 NM_001242956 NM_001788	SEPT7	septin 7
chr11_-_12030622	10.466	NM_015881	DKK3	dickkopf 3 homolog (Xenopus laevis)
chr19_-_42498221	10.443		ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr12_+_77157885	10.275		ZDHHC17	zinc finger, DHHC-type containing 17
chr3_-_14989399	10.248		LOC100505641	uncharacterized LOC100505641
chr3_-_171177851	10.247	NM_001161560 NM_001161561 NM_001161562 NM_001161563 NM_001161564 NM_001161565 NM_001161566 NM_015028	TNIK	TRAF2 and NCK interacting kinase
chr7_-_143059144	10.234	NM_014690	FAM131B	family with sequence similarity 131, member B
chr19_-_36523770	10.191	NM_015526	CLIP3	CAP-GLY domain containing linker protein 3
chr1_+_169075869	10.179	NM_001677	ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr4_+_71570768	10.081		RUFY3	RUN and FYVE domain containing 3
chr15_-_73925658	10.041	NM_001161363 NM_001161364 NM_012428 NM_017455	NPTN	neuroplastin
chr7_+_45614081	9.961	NM_021116	ADCY1	adenylate cyclase 1 (brain)
chr22_+_39745757	9.927	NM_004711 NM_145731	SYNGR1	synaptogyrin 1
chr1_+_33352071	9.915	NM_002143	HPCA	hippocalcin
chrX_-_70288155	9.885	NM_013346	SNX12	sorting nexin 12
chr10_+_111985628	9.868	NM_005962	MXI1	MAX interactor 1
chr8_-_144241918	9.848	NM_001130478	LY6H	lymphocyte antigen 6 complex, locus H
chr9_-_135230129	9.809		SETX	senataxin
chr1_+_65720091	9.769		LOC645195 DNAJC6	uncharacterized LOC645195 DnaJ (Hsp40) homolog, subfamily C, member 6
chr2_+_149633173	9.733
chr13_+_98086315	9.682	NM_021033	RAP2A	RAP2A, member of RAS oncogene family
chr11_-_123525300	9.645	NM_001040151 NM_018400	SCN3B	sodium channel, voltage-gated, type III, beta
chr13_-_80915041	9.579	NM_005842	SPRY2	sprouty homolog 2 (Drosophila)
chr7_-_32931363	9.577		KBTBD2	kelch repeat and BTB (POZ) domain containing 2
chr5_+_137801178	9.575	NM_001964	EGR1	early growth response 1
chr9_+_123963728	9.496		GSN	gelsolin
chr4_-_36245893	9.465	NM_015230	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_-_123524881	9.463		SCN3B	sodium channel, voltage-gated, type III, beta
chr5_+_137801166	9.449		EGR1	early growth response 1
chr12_+_121078421	9.444	NM_001033677	CABP1	calcium binding protein 1
chr19_+_18794391	9.431	NM_001098482 NM_015321	CRTC1	CREB regulated transcription coactivator 1
chr6_+_107811272	9.396	NM_018013	SOBP	sine oculis binding protein homolog (Drosophila)
chr1_-_200638996	9.394		DDX59	DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr20_-_48099178	9.392	NM_004975	KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1
chr16_+_2588000	9.352		PDPK1	3-phosphoinositide dependent protein kinase-1
chr19_+_35760002	9.330		USF2	upstream transcription factor 2, c-fos interacting
chr19_+_36266366	9.197	NM_001172630 NM_052948	ARHGAP33	Rho GTPase activating protein 33
chr19_+_16435734	9.106		KLF2	Kruppel-like factor 2 (lung)
chrX_-_51239426	8.962	NM_018159	NUDT11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chrX_+_47092264	8.932	NM_004651	USP11	ubiquitin specific peptidase 11
chr1_+_77747727	8.880		AK5	adenylate kinase 5
chr20_-_61569265	8.771	NM_022105 NM_033081 NM_080797	DIDO1	death inducer-obliterator 1
chr7_+_95401817	8.762	NM_001135556 NM_001135557 NM_004411	DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1
chr7_+_24323806	8.743	NM_000905	NPY	neuropeptide Y
chr11_-_236324	8.716	NM_001017524 NM_012239	SIRT3	sirtuin 3
chr5_-_11903964	8.686	NM_001332	CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr2_+_139259476	8.685
chr1_-_32229635	8.683	NM_001703	BAI2	brain-specific angiogenesis inhibitor 2
chr19_-_13617037	8.675	NM_000068 NM_001127221 NM_001127222 NM_001174080 NM_023035	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr10_-_75634219	8.666	NM_001204492 NM_001222 NM_172169 NM_172170 NM_172171 NM_172173	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma
chr13_+_42846255	8.630	NM_016248	AKAP11	A kinase (PRKA) anchor protein 11
chr3_-_14988976	8.628		LOC100505641	uncharacterized LOC100505641
chr6_-_84419108	8.578	NM_001242793 NM_001242794 NM_014841	SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr16_+_28834407	8.573	NM_007245 NM_145714 NM_148414 NM_148415 NM_148416	ATXN2L	ataxin 2-like
chr3_-_9439122	8.565		LOC440944	uncharacterized LOC440944
chr17_+_30813928	8.543	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr14_+_29236171	8.511	NM_005249	FOXG1	forkhead box G1
chr16_+_2587989	8.504		PDPK1	3-phosphoinositide dependent protein kinase-1
chr16_+_2588021	8.461		PDPK1	3-phosphoinositide dependent protein kinase-1
chr10_-_75255747	8.444	NM_001142353 NM_001142354 NM_021132	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme
chr2_-_25896282	8.374	NM_021907 NM_033147 NM_033148 NM_183360 NM_183361	DTNB	dystrobrevin, beta
chr3_+_20081853	8.353		KAT2B	K(lysine) acetyltransferase 2B
chr12_-_133532847	8.343	NM_183238 NM_001164715	ZNF605	zinc finger protein 605
chr19_+_589849	8.334	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr8_-_144241678	8.287		LY6H	lymphocyte antigen 6 complex, locus H
chr20_+_19193364	8.268		SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr3_-_45267804	8.153	NM_015444	TMEM158	transmembrane protein 158 (gene/pseudogene)
chr13_-_45150601	8.152	NM_001243799 NM_183422	TSC22D1	TSC22 domain family, member 1
chr11_+_45907198	8.149		MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1
chr8_+_1922030	8.140	NM_014867	KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr10_+_124220990	8.137	NM_002775	HTRA1	HtrA serine peptidase 1
chr20_+_19193282	8.123	NM_020689	SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr17_+_77751929	8.058	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr16_+_2039945	8.023	NM_004209	SYNGR3	synaptogyrin 3
chr19_+_11457160	7.999	NM_001080503	CCDC159	coiled-coil domain containing 159
chr5_+_76506705	7.986	NM_001029851 NM_001029852 NM_001029853 NM_001029854 NM_003719	PDE8B	phosphodiesterase 8B
chr3_-_57113292	7.962	NM_001128615	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr2_-_99552677	7.948	NM_207362	C2orf55	chromosome 2 open reading frame 55
chr15_+_80696569	7.914	NM_014862	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr4_-_105412466	7.890	NM_025212	CXXC4	CXXC finger protein 4
chr7_-_150946031	7.870		SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_+_154301219	7.856		ATP8B2	ATPase, class I, type 8B, member 2
chr19_+_47524142	7.846	NM_002517	NPAS1	neuronal PAS domain protein 1
chr5_+_7396030	7.832	NM_020546	ADCY2	adenylate cyclase 2 (brain)
chr16_+_28834372	7.771		ATXN2L	ataxin 2-like
chr8_+_94929082	7.768	NM_018444 NM_001161780 NM_001161779 NM_001161781	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr3_+_58223228	7.756	NM_020676	ABHD6	abhydrolase domain containing 6
chr7_+_139877154	7.752		LOC100134229	uncharacterized LOC100134229
chr7_-_102257135	7.748		RASA4	RAS p21 protein activator 4
chr15_-_83316621	7.726	NM_030594	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr7_-_129251465	7.721
chr18_-_29522988	7.710		TRAPPC8	trafficking protein particle complex 8
chr3_-_14988939	7.707		LOC100505641	uncharacterized LOC100505641
chr12_+_7023490	7.703	NM_001975	ENO2	enolase 2 (gamma, neuronal)
chr19_+_18794487	7.701		CRTC1	CREB regulated transcription coactivator 1
chr4_-_5890266	7.688	NM_001313	CRMP1	collapsin response mediator protein 1
chr12_+_77157842	7.658	NM_015336	ZDHHC17	zinc finger, DHHC-type containing 17
chr19_+_39833099	7.628	NM_018028	SAMD4B	sterile alpha motif domain containing 4B
chr16_-_3930713	7.620		CREBBP	CREB binding protein
chr5_+_34929679	7.570	NM_001012339 NM_194283	DNAJC21	DnaJ (Hsp40) homolog, subfamily C, member 21
chr11_+_107461807	7.522	NM_001130037 NM_018712	ELMOD1	ELMO/CED-12 domain containing 1
chr11_-_113746205	7.518	NM_020886	USP28	ubiquitin specific peptidase 28
chr19_-_18654376	7.511	NM_012181	FKBP8	FK506 binding protein 8, 38kDa
chr18_-_53255734	7.483	NM_001083962 NM_001243230 NM_003199	TCF4	transcription factor 4
chr19_-_815243	7.419		LPPR3	lipid phosphate phosphatase-related protein type 3
chr9_+_35605614	7.419		TESK1	testis-specific kinase 1
chrX_-_135333519	7.415	NM_001173517 NM_024597	MAP7D3	MAP7 domain containing 3
chr8_-_144241456	7.414	NM_002347	LY6H	lymphocyte antigen 6 complex, locus H
chr22_+_19711065	7.410	NM_000407	GP1BB	glycoprotein Ib (platelet), beta polypeptide
chr7_+_73703704	7.404	NM_003388 NM_032421	CLIP2	CAP-GLY domain containing linker protein 2
chr15_-_65425650	7.369	NM_005707	PDCD7	programmed cell death 7
chr2_+_30369868	7.351		YPEL5	yippee-like 5 (Drosophila)
chr4_+_1795004	7.313	NM_000142 NM_001163213 NM_022965	FGFR3	fibroblast growth factor receptor 3
chr3_-_13008959	7.301	NM_014869	IQSEC1	IQ motif and Sec7 domain 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.28	3.86e-34	GO:0050794	regulation of cellular process
1.25	5.83e-33	GO:0065007	biological regulation
1.26	5.17e-32	GO:0050789	regulation of biological process
1.43	1.17e-31	GO:0023052	signaling
1.74	5.32e-30	GO:0007399	nervous system development
1.15	2.32e-29	GO:0009987	cellular process
1.35	2.58e-21	GO:0032502	developmental process
1.38	9.38e-21	GO:0007165	signal transduction
1.58	1.15e-20	GO:0023051	regulation of signaling
1.36	1.66e-19	GO:0007275	multicellular organismal development
1.78	4.88e-19	GO:0022008	neurogenesis
1.40	4.88e-19	GO:0048731	system development
1.37	1.47e-18	GO:0048856	anatomical structure development
2.07	3.51e-18	GO:0019226	transmission of nerve impulse
2.07	3.51e-18	GO:0035637	multicellular organismal signaling
1.78	5.04e-18	GO:0048699	generation of neurons
2.06	7.65e-16	GO:0007268	synaptic transmission
1.44	1.63e-15	GO:0048869	cellular developmental process
1.44	5.81e-15	GO:0030154	cell differentiation
1.96	1.16e-14	GO:0000904	cell morphogenesis involved in differentiation
1.52	1.55e-14	GO:0009653	anatomical structure morphogenesis
2.04	2.29e-14	GO:0007409	axonogenesis
2.01	4.10e-14	GO:0048667	cell morphogenesis involved in neuron differentiation
1.27	7.55e-14	GO:0051716	cellular response to stimulus
1.84	8.32e-14	GO:0000902	cell morphogenesis
1.99	8.72e-14	GO:0048812	neuron projection morphogenesis
1.77	1.07e-13	GO:0030182	neuron differentiation
1.61	1.08e-13	GO:0010646	regulation of cell communication
1.80	1.31e-13	GO:0007167	enzyme linked receptor protein signaling pathway
1.91	1.45e-13	GO:0032990	cell part morphogenesis
1.92	1.46e-13	GO:0048858	cell projection morphogenesis
1.30	1.69e-13	GO:0031323	regulation of cellular metabolic process
1.28	2.20e-13	GO:0019222	regulation of metabolic process
1.38	4.30e-13	GO:0048519	negative regulation of biological process
1.30	4.56e-13	GO:0080090	regulation of primary metabolic process
1.44	4.82e-13	GO:0007166	cell surface receptor linked signaling pathway
1.50	1.15e-12	GO:0009966	regulation of signal transduction
1.39	1.87e-12	GO:0048523	negative regulation of cellular process
1.89	2.16e-12	GO:0031175	neuron projection development
1.77	4.76e-12	GO:0032989	cellular component morphogenesis
1.69	7.11e-12	GO:0007267	cell-cell signaling
1.42	7.97e-12	GO:0006464	protein modification process
1.51	8.66e-12	GO:0051239	regulation of multicellular organismal process
1.76	9.54e-12	GO:0030030	cell projection organization
1.28	1.00e-11	GO:0051179	localization
1.61	1.65e-11	GO:0048468	cell development
1.33	2.84e-11	GO:0031326	regulation of cellular biosynthetic process
1.60	4.23e-11	GO:0050793	regulation of developmental process
2.03	5.75e-11	GO:0007411	axon guidance
1.77	6.87e-11	GO:0048666	neuron development
1.32	7.74e-11	GO:0009889	regulation of biosynthetic process
1.81	1.10e-10	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.28	1.41e-10	GO:0060255	regulation of macromolecule metabolic process
1.32	1.53e-10	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.57	1.84e-10	GO:0032879	regulation of localization
1.47	2.85e-10	GO:0035556	intracellular signal transduction
1.27	5.41e-10	GO:0016043	cellular component organization
1.59	5.93e-10	GO:0006351	transcription, DNA-dependent
1.38	6.85e-10	GO:0048583	regulation of response to stimulus
1.38	6.96e-10	GO:0043412	macromolecule modification
1.54	1.41e-09	GO:0007154	cell communication
1.32	1.73e-09	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.63	2.08e-09	GO:2000026	regulation of multicellular organismal development
1.20	2.28e-09	GO:0032501	multicellular organismal process
1.34	4.29e-09	GO:0006355	regulation of transcription, DNA-dependent
1.30	4.52e-09	GO:0051171	regulation of nitrogen compound metabolic process
1.30	8.09e-09	GO:0010468	regulation of gene expression
1.31	1.08e-08	GO:0010556	regulation of macromolecule biosynthetic process
1.27	1.50e-08	GO:0051234	establishment of localization
1.25	2.08e-08	GO:0071840	cellular component organization or biogenesis
1.27	2.34e-08	GO:0006810	transport
1.32	2.46e-08	GO:0051252	regulation of RNA metabolic process
1.59	2.63e-08	GO:0016192	vesicle-mediated transport
1.61	7.18e-08	GO:0045595	regulation of cell differentiation
1.49	1.32e-07	GO:0006793	phosphorus metabolic process
1.49	1.32e-07	GO:0006796	phosphate metabolic process
1.60	1.47e-07	GO:0010628	positive regulation of gene expression
1.70	1.79e-07	GO:0007417	central nervous system development
1.30	1.93e-07	GO:0042221	response to chemical stimulus
1.31	2.37e-07	GO:0065008	regulation of biological quality
1.57	2.60e-07	GO:0006468	protein phosphorylation
1.48	3.11e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.28	3.33e-07	GO:0071842	cellular component organization at cellular level
1.42	3.34e-07	GO:0051641	cellular localization
1.29	3.86e-07	GO:0048522	positive regulation of cellular process
1.27	5.20e-07	GO:0048518	positive regulation of biological process
1.53	5.41e-07	GO:0051128	regulation of cellular component organization
1.19	9.34e-07	GO:0044260	cellular macromolecule metabolic process
1.71	1.50e-06	GO:0051094	positive regulation of developmental process
1.46	2.80e-06	GO:0032774	RNA biosynthetic process
1.15	2.95e-06	GO:0044237	cellular metabolic process
1.42	3.34e-06	GO:0051649	establishment of localization in cell
1.71	3.79e-06	GO:0060341	regulation of cellular localization
1.53	4.31e-06	GO:0051049	regulation of transport
1.65	4.59e-06	GO:0048585	negative regulation of response to stimulus
1.82	5.89e-06	GO:0060284	regulation of cell development
1.73	6.98e-06	GO:0007264	small GTPase mediated signal transduction
2.35	7.29e-06	GO:0002791	regulation of peptide secretion
2.35	7.29e-06	GO:0090087	regulation of peptide transport
2.88	8.43e-06	GO:0007269	neurotransmitter secretion
2.41	8.79e-06	GO:0003001	generation of a signal involved in cell-cell signaling
2.41	8.79e-06	GO:0023061	signal release
1.57	8.84e-06	GO:0045893	positive regulation of transcription, DNA-dependent
1.86	8.86e-06	GO:0051960	regulation of nervous system development
1.68	9.71e-06	GO:0023057	negative regulation of signaling
1.25	9.75e-06	GO:0071841	cellular component organization or biogenesis at cellular level
1.67	1.14e-05	GO:0010648	negative regulation of cell communication
1.47	1.15e-05	GO:0040011	locomotion
2.34	1.24e-05	GO:0090276	regulation of peptide hormone secretion
1.54	1.63e-05	GO:0051254	positive regulation of RNA metabolic process
2.37	1.79e-05	GO:0050796	regulation of insulin secretion
1.72	2.11e-05	GO:0051056	regulation of small GTPase mediated signal transduction
1.94	2.34e-05	GO:0048011	nerve growth factor receptor signaling pathway
1.69	2.45e-05	GO:0009968	negative regulation of signal transduction
1.46	2.86e-05	GO:0016310	phosphorylation
1.34	3.37e-05	GO:0065009	regulation of molecular function
1.90	3.65e-05	GO:0006897	endocytosis
1.90	3.65e-05	GO:0010324	membrane invagination
1.49	3.91e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51	4.12e-05	GO:0031327	negative regulation of cellular biosynthetic process
1.88	4.44e-05	GO:0050767	regulation of neurogenesis
2.15	4.49e-05	GO:0046883	regulation of hormone secretion
1.47	5.12e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.54	5.37e-05	GO:0009725	response to hormone stimulus
1.50	6.49e-05	GO:0009890	negative regulation of biosynthetic process
1.51	8.36e-05	GO:0009719	response to endogenous stimulus
1.13	8.51e-05	GO:0044238	primary metabolic process
2.45	8.79e-05	GO:0001505	regulation of neurotransmitter levels
1.58	9.76e-05	GO:0006935	chemotaxis
1.58	9.76e-05	GO:0042330	taxis
1.57	9.77e-05	GO:0045892	negative regulation of transcription, DNA-dependent
1.41	1.04e-04	GO:0009892	negative regulation of metabolic process
1.56	1.11e-04	GO:0051253	negative regulation of RNA metabolic process
1.71	1.68e-04	GO:0045597	positive regulation of cell differentiation
1.52	1.70e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.74	1.78e-04	GO:0032870	cellular response to hormone stimulus
1.52	1.97e-04	GO:0010629	negative regulation of gene expression
1.15	2.07e-04	GO:0043170	macromolecule metabolic process
1.37	2.13e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.51	2.29e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.46	2.40e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
1.73	2.64e-04	GO:0022603	regulation of anatomical structure morphogenesis
2.28	2.90e-04	GO:0006836	neurotransmitter transport
1.13	3.12e-04	GO:0050896	response to stimulus
1.70	3.47e-04	GO:0071495	cellular response to endogenous stimulus
1.50	3.70e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.41	4.98e-04	GO:0031324	negative regulation of cellular metabolic process
1.48	5.14e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.42	5.72e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.65	6.92e-04	GO:0007420	brain development
1.69	7.03e-04	GO:0051046	regulation of secretion
1.41	8.04e-04	GO:0009891	positive regulation of biosynthetic process
1.43	8.24e-04	GO:0046907	intracellular transport
1.57	9.93e-04	GO:0061024	membrane organization
4.54	9.96e-04	GO:0014047	glutamate secretion
1.22	1.19e-03	GO:0044267	cellular protein metabolic process
1.66	1.34e-03	GO:0043434	response to peptide hormone stimulus
1.57	1.39e-03	GO:0016044	cellular membrane organization
2.02	1.58e-03	GO:0006184	GTP catabolic process
2.06	2.30e-03	GO:0051969	regulation of transmission of nerve impulse
1.74	2.31e-03	GO:0030334	regulation of cell migration
1.32	2.31e-03	GO:0009893	positive regulation of metabolic process
1.11	2.70e-03	GO:0008152	metabolic process
1.32	2.70e-03	GO:0010033	response to organic substance
1.38	2.85e-03	GO:0010605	negative regulation of macromolecule metabolic process
2.21	3.15e-03	GO:0048754	branching morphogenesis of a tube
1.99	3.24e-03	GO:0031644	regulation of neurological system process
1.20	3.37e-03	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.53	3.64e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.82	3.69e-03	GO:0045664	regulation of neuron differentiation
1.72	3.90e-03	GO:2000145	regulation of cell motility
3.19	4.11e-03	GO:0048489	synaptic vesicle transport
1.69	4.69e-03	GO:0035295	tube development
1.35	5.52e-03	GO:0009605	response to external stimulus
2.08	5.56e-03	GO:0050804	regulation of synaptic transmission
1.67	5.83e-03	GO:0051270	regulation of cellular component movement
1.42	6.01e-03	GO:0019220	regulation of phosphate metabolic process
1.42	6.01e-03	GO:0051174	regulation of phosphorus metabolic process
1.46	6.07e-03	GO:0009887	organ morphogenesis
1.43	6.66e-03	GO:0042325	regulation of phosphorylation
1.30	7.61e-03	GO:0033036	macromolecule localization
1.31	8.19e-03	GO:0031325	positive regulation of cellular metabolic process
1.73	9.09e-03	GO:0030168	platelet activation
1.33	9.10e-03	GO:0051246	regulation of protein metabolic process
1.74	9.93e-03	GO:0071375	cellular response to peptide hormone stimulus
2.00	9.97e-03	GO:0001763	morphogenesis of a branching structure
2.00	9.97e-03	GO:0010769	regulation of cell morphogenesis involved in differentiation
2.35	1.12e-02	GO:0048638	regulation of developmental growth
1.59	1.14e-02	GO:0018193	peptidyl-amino acid modification
1.62	1.16e-02	GO:0032940	secretion by cell
1.60	1.20e-02	GO:0044057	regulation of system process
1.99	1.27e-02	GO:0022604	regulation of cell morphogenesis
1.97	1.29e-02	GO:0042391	regulation of membrane potential
1.89	1.30e-02	GO:0046039	GTP metabolic process
1.95	1.30e-02	GO:0008286	insulin receptor signaling pathway
1.73	1.41e-02	GO:0002009	morphogenesis of an epithelium
3.69	1.46e-02	GO:0018107	peptidyl-threonine phosphorylation
2.08	1.76e-02	GO:0010720	positive regulation of cell development
1.42	1.93e-02	GO:0001932	regulation of protein phosphorylation
1.63	1.94e-02	GO:0040012	regulation of locomotion
1.23	1.97e-02	GO:0048513	organ development
1.94	2.06e-02	GO:0006112	energy reserve metabolic process
1.80	2.11e-02	GO:0035239	tube morphogenesis
1.32	2.20e-02	GO:0032268	regulation of cellular protein metabolic process
1.37	2.45e-02	GO:0031399	regulation of protein modification process
1.53	2.47e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.63	2.55e-02	GO:0032446	protein modification by small protein conjugation
2.30	2.68e-02	GO:0050770	regulation of axonogenesis
1.54	2.72e-02	GO:0090066	regulation of anatomical structure size
1.61	2.85e-02	GO:0006366	transcription from RNA polymerase II promoter
2.07	2.86e-02	GO:0021700	developmental maturation
1.57	2.96e-02	GO:0070647	protein modification by small protein conjugation or removal
2.04	2.97e-02	GO:0061138	morphogenesis of a branching epithelium
1.50	3.10e-02	GO:0032583	regulation of gene-specific transcription
1.39	3.15e-02	GO:0009790	embryo development
1.66	3.29e-02	GO:0000165	MAPKKK cascade
1.69	3.48e-02	GO:0032868	response to insulin stimulus
1.54	3.52e-02	GO:0009792	embryo development ending in birth or egg hatching
1.31	3.53e-02	GO:0008104	protein localization
1.76	3.56e-02	GO:0048732	gland development
1.24	3.77e-02	GO:0006996	organelle organization
1.54	4.06e-02	GO:0016568	chromatin modification
1.59	4.39e-02	GO:0048729	tissue morphogenesis
2.18	4.57e-02	GO:0050769	positive regulation of neurogenesis
1.64	4.68e-02	GO:0016567	protein ubiquitination
1.77	4.82e-02	GO:0032869	cellular response to insulin stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.13	3.70e-24	GO:0005622	intracellular
1.13	4.42e-22	GO:0044424	intracellular part
1.99	4.77e-14	GO:0045202	synapse
1.13	1.99e-13	GO:0043226	organelle
1.15	7.78e-13	GO:0005737	cytoplasm
1.12	8.14e-13	GO:0043229	intracellular organelle
1.19	1.98e-10	GO:0005634	nucleus
1.12	2.63e-10	GO:0043227	membrane-bounded organelle
1.12	7.13e-10	GO:0043231	intracellular membrane-bounded organelle
1.97	1.15e-09	GO:0044456	synapse part
1.30	3.13e-08	GO:0044459	plasma membrane part
1.05	3.69e-08	GO:0005623	cell
1.53	4.68e-08	GO:0031982	vesicle
1.04	5.24e-08	GO:0044464	cell part
1.73	1.97e-07	GO:0043005	neuron projection
1.47	5.49e-07	GO:0042995	cell projection
1.50	7.08e-07	GO:0031410	cytoplasmic vesicle
1.51	9.43e-07	GO:0031988	membrane-bounded vesicle
1.54	4.34e-06	GO:0030054	cell junction
1.49	5.45e-06	GO:0016023	cytoplasmic membrane-bounded vesicle
2.01	2.88e-05	GO:0030136	clathrin-coated vesicle
2.29	4.92e-05	GO:0019717	synaptosome
2.78	1.65e-04	GO:0005905	coated pit
1.15	5.77e-04	GO:0071944	cell periphery
2.27	5.91e-04	GO:0030665	clathrin coated vesicle membrane
1.84	6.75e-04	GO:0031252	cell leading edge
1.98	7.21e-04	GO:0034703	cation channel complex
1.15	1.05e-03	GO:0005886	plasma membrane
2.22	1.11e-03	GO:0008021	synaptic vesicle
2.22	1.11e-03	GO:0008076	voltage-gated potassium channel complex
2.22	1.11e-03	GO:0034705	potassium channel complex
1.37	1.15e-03	GO:0005624	membrane fraction
1.37	1.23e-03	GO:0005626	insoluble fraction
1.11	1.28e-03	GO:0044444	cytoplasmic part
1.76	1.96e-03	GO:0030135	coated vesicle
1.17	2.77e-03	GO:0043234	protein complex
2.24	3.45e-03	GO:0033267	axon part
1.21	3.58e-03	GO:0005829	cytosol
1.77	4.29e-03	GO:0030424	axon
1.38	4.98e-03	GO:0015630	microtubule cytoskeleton
1.53	6.79e-03	GO:0048471	perinuclear region of cytoplasm
1.29	8.06e-03	GO:0000267	cell fraction
1.72	8.12e-03	GO:0030425	dendrite
1.36	1.01e-02	GO:0044451	nucleoplasm part
1.22	1.03e-02	GO:0031981	nuclear lumen
1.80	1.21e-02	GO:0045211	postsynaptic membrane
2.04	1.64e-02	GO:0001726	ruffle
1.97	1.76e-02	GO:0019898	extrinsic to membrane
1.25	1.95e-02	GO:0005654	nucleoplasm
1.55	2.39e-02	GO:0005874	microtubule
1.22	2.53e-02	GO:0005856	cytoskeleton
1.64	2.55e-02	GO:0034702	ion channel complex
1.55	2.94e-02	GO:0012506	vesicle membrane
1.43	3.10e-02	GO:0005768	endosome
1.18	4.95e-02	GO:0044428	nuclear part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.24	6.95e-29	GO:0005515	protein binding
1.13	7.68e-26	GO:0005488	binding
1.58	1.54e-12	GO:0001071	nucleic acid binding transcription factor activity
1.58	1.54e-12	GO:0003700	sequence-specific DNA binding transcription factor activity
1.53	1.17e-10	GO:0030528	transcription regulator activity
1.79	1.86e-10	GO:0060589	nucleoside-triphosphatase regulator activity
1.80	2.06e-10	GO:0030695	GTPase regulator activity
1.64	5.50e-10	GO:0043565	sequence-specific DNA binding
1.59	6.57e-09	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.33	3.99e-08	GO:0017076	purine nucleotide binding
1.53	8.57e-08	GO:0016301	kinase activity
1.32	8.99e-08	GO:0032553	ribonucleotide binding
1.32	8.99e-08	GO:0032555	purine ribonucleotide binding
1.29	1.67e-07	GO:0000166	nucleotide binding
1.59	2.10e-07	GO:0004672	protein kinase activity
1.69	4.47e-07	GO:0019904	protein domain specific binding
1.69	4.71e-07	GO:0004674	protein serine/threonine kinase activity
1.31	4.77e-07	GO:0035639	purine ribonucleoside triphosphate binding
1.83	1.55e-06	GO:0008134	transcription factor binding
1.49	3.60e-06	GO:0019899	enzyme binding
1.43	6.49e-06	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.26	6.80e-06	GO:0003677	DNA binding
1.94	1.15e-05	GO:0000975	regulatory region DNA binding
1.94	1.15e-05	GO:0001067	regulatory region nucleic acid binding
1.94	1.15e-05	GO:0044212	transcription regulatory region DNA binding
1.77	1.43e-05	GO:0005083	small GTPase regulator activity
1.71	4.19e-05	GO:0016563	transcription activator activity
1.39	6.63e-05	GO:0030234	enzyme regulator activity
1.90	6.96e-05	GO:0010843	promoter binding
1.16	2.91e-04	GO:0046872	metal ion binding
2.00	4.04e-04	GO:0022843	voltage-gated cation channel activity
1.73	4.41e-04	GO:0005096	GTPase activator activity
1.28	5.28e-04	GO:0030554	adenyl nucleotide binding
1.16	5.54e-04	GO:0043169	cation binding
1.16	6.51e-04	GO:0043167	ion binding
1.71	1.15e-03	GO:0003702	RNA polymerase II transcription factor activity
1.27	1.20e-03	GO:0032559	adenyl ribonucleotide binding
1.56	1.26e-03	GO:0008047	enzyme activator activity
1.96	1.31e-03	GO:0005516	calmodulin binding
1.89	1.31e-03	GO:0005085	guanyl-nucleotide exchange factor activity
1.54	3.92e-03	GO:0000988	protein binding transcription factor activity
1.54	3.92e-03	GO:0000989	transcription factor binding transcription factor activity
1.44	4.73e-03	GO:0008092	cytoskeletal protein binding
2.09	5.46e-03	GO:0005249	voltage-gated potassium channel activity
1.37	5.53e-03	GO:0042802	identical protein binding
1.53	6.16e-03	GO:0003712	transcription cofactor activity
4.65	6.61e-03	GO:0030742	GTP-dependent protein binding
1.25	7.61e-03	GO:0005524	ATP binding
1.71	8.10e-03	GO:0003924	GTPase activity
1.21	9.62e-03	GO:0008270	zinc ion binding
1.61	9.95e-03	GO:0005261	cation channel activity
1.57	1.04e-02	GO:0016564	transcription repressor activity
1.57	1.19e-02	GO:0022836	gated channel activity
1.94	1.60e-02	GO:0015631	tubulin binding
1.15	2.25e-02	GO:0003676	nucleic acid binding
1.99	2.47e-02	GO:0005057	receptor signaling protein activity
2.52	2.85e-02	GO:0046332	SMAD binding
5.68	3.10e-02	GO:0019789	SUMO ligase activity
1.49	3.61e-02	GO:0005525	GTP binding
1.85	3.77e-02	GO:0005267	potassium channel activity
2.00	4.88e-02	GO:0005088	Ras guanyl-nucleotide exchange factor activity