Motif ID: EOMES.p2

Z-value: 1.256


Transcription factors associated with EOMES.p2:

Gene SymbolEntrez IDGene Name
EOMES 8320 eomesodermin



Activity profile for motif EOMES.p2.

activity profile for motif EOMES.p2


Sorted Z-values histogram for motif EOMES.p2

Sorted Z-values for motif EOMES.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EOMES.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_5271035 19.971 NM_000559
HBG1
hemoglobin, gamma A
chr14_+_95078713 16.397 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr11_-_33913835 13.814 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr10_+_114135965 13.271 ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_-_112041253 12.073 NM_153047
FYN
FYN oncogene related to SRC, FGR, YES
chr2_-_157189040 12.053 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_+_69742130 10.687 NM_000239
LYZ
lysozyme
chr1_+_55464605 10.001 NM_057176
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr12_+_69742140 9.991 LYZ
lysozyme
chr17_+_25958257 9.781 LGALS9
lectin, galactoside-binding, soluble, 9
chr4_-_186732208 9.587 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr17_+_25958217 9.522 LGALS9
lectin, galactoside-binding, soluble, 9
chr12_-_89746238 9.352 DUSP6
dual specificity phosphatase 6
chr12_-_89745997 9.314 DUSP6
dual specificity phosphatase 6
chr12_-_89746244 9.240 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr17_+_25958245 9.164 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958151 8.542 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr17_+_25958192 8.426 LGALS9
lectin, galactoside-binding, soluble, 9
chr10_+_114135937 8.354 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr5_-_131132642 8.325 FNIP1
folliculin interacting protein 1
chr5_-_39270708 8.171 NM_001243093
FYB
FYN binding protein
chr16_+_77233348 8.163 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr4_-_186732047 7.952 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr11_-_5275904 7.481 NM_000184
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr10_+_114136014 7.472 ACSL5
acyl-CoA synthetase long-chain family member 5
chr4_-_57547845 7.437 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr2_+_219246751 7.328 NM_000578
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr5_+_54320083 7.327 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr8_-_120651019 7.166 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr9_+_17134974 7.154 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr7_-_36764000 7.094 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chr4_+_160188997 7.079 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_+_145438437 7.045 NM_006472
TXNIP
thioredoxin interacting protein
chr1_-_156786500 6.875 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr3_-_49459870 6.747 AMT
aminomethyltransferase
chr19_-_36236291 6.384 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr10_+_70847817 6.339 NM_002727
SRGN
serglycin
chr6_+_99872769 6.331


chr8_-_146202727 6.262 ZNF252
zinc finger protein 252
chr21_-_46340821 6.115 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_34043234 6.043 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr3_-_133748727 6.042 SLCO2A1
solute carrier organic anion transporter family, member 2A1
chrX_+_70443055 6.030 NM_000166
GJB1
gap junction protein, beta 1, 32kDa
chr16_+_30386097 6.000 NM_013292
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr21_-_46340776 5.999 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr12_-_6233684 5.876 NM_000552
VWF
von Willebrand factor
chr15_+_74421986 5.816 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_+_182758871 5.803 NPL
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr1_-_11907741 5.707 NM_006172
NPPA
natriuretic peptide A
chr8_+_1993157 5.498 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr17_+_8213555 5.496 NM_173728
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr14_-_107013474 5.418 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_131894343 5.371 NM_000045
NM_001244438
ARG1

arginase, liver

chr10_+_70847857 5.370 SRGN
serglycin
chr4_-_186578122 5.345 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr7_+_150264457 5.345 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr3_-_187463474 5.253 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr17_-_42345434 5.250 NM_000342
SLC4A1
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr14_-_107113943 5.230 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_-_133748828 5.070 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr5_+_148206155 5.055 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr1_-_116311161 5.048 CASQ2
calsequestrin 2 (cardiac muscle)
chr14_+_21467413 4.988 NM_014579
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr8_-_11705259 4.940


chr4_-_186577858 4.900 SORBS2
sorbin and SH3 domain containing 2
chr6_-_32497925 4.803 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr17_+_18380097 4.652 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr14_-_24036532 4.650 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr17_-_56406120 4.639 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr11_+_73358593 4.638 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr4_+_124317884 4.594 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr5_+_35856990 4.575 NM_002185
IL7R
interleukin 7 receptor
chr12_-_45269953 4.427 NELL2
NEL-like 2 (chicken)
chr19_+_14017038 4.395 CC2D1A
coiled-coil and C2 domain containing 1A
chr1_+_38022514 4.385 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr19_+_47813074 4.356 NM_001736
C5AR1
complement component 5a receptor 1
chr9_+_102584136 4.336 NM_006981
NM_173199
NM_173200
NR4A3


nuclear receptor subfamily 4, group A, member 3


chr3_+_38347426 4.331 NM_004803
SLC22A14
solute carrier family 22, member 14
chr10_+_114135013 4.253 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_212781969 4.224 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr6_+_39760148 4.214 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr17_-_10452939 4.166 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chrX_-_107018889 4.156 TSC22D3
TSC22 domain family, member 3
chr3_+_137728949 4.134 NM_016369
CLDN18
claudin 18
chr17_+_8339135 4.110 NM_001025579
NM_030808
NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

chr17_+_8214139 4.097 NM_025014
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr17_-_61973870 4.081 NM_001317
CSH1
chorionic somatomammotropin hormone 1 (placental lactogen)
chr5_+_156820161 4.035 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr19_-_14016908 4.015 NM_024323
C19orf57
chromosome 19 open reading frame 57
chr16_+_57702156 4.011 NM_170776
GPR97
G protein-coupled receptor 97
chr3_-_195310985 3.969 NM_001647
APOD
apolipoprotein D
chr17_-_61996135 3.954 NM_000515
NM_022559
NM_022560
NM_022561
NM_022562
GH1




growth hormone 1




chrX_-_15873094 3.932 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr14_+_55034633 3.887 SAMD4A
sterile alpha motif domain containing 4A
chrX_+_69642880 3.884 NM_001171191
NM_001171192
NM_001171193
NM_017711
GDPD2



glycerophosphodiester phosphodiesterase domain containing 2



chr10_+_135051407 3.881 NM_014468
VENTX
VENT homeobox
chr19_-_1020995 3.880 C19orf6
chromosome 19 open reading frame 6
chr1_-_44482996 3.826 NM_006934
NM_201649
SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr5_-_1882764 3.816 NM_016358
IRX4
iroquois homeobox 4
chr9_-_79520878 3.801 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr6_-_13487772 3.769 NM_001242629
NM_018988
GFOD1

glucose-fructose oxidoreductase domain containing 1

chr14_-_76447445 3.762 TGFB3
transforming growth factor, beta 3
chr7_-_150652861 3.745 NM_001204798
NM_172057
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr6_+_32132379 3.734 NM_030652
EGFL8
EGF-like-domain, multiple 8
chr6_-_46459710 3.691 NM_001251973
RCAN2
regulator of calcineurin 2
chr8_-_67090690 3.683 NM_000756
CRH
corticotropin releasing hormone
chr1_+_153600859 3.595 NM_006271
S100A1
S100 calcium binding protein A1
chr18_-_24442534 3.566 NM_004028
AQP4
aquaporin 4
chr1_+_212782103 3.551 ATF3
activating transcription factor 3
chr19_+_47524142 3.545 NM_002517
NPAS1
neuronal PAS domain protein 1
chr17_-_20370819 3.508 NM_001042685
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr11_+_63606598 3.497 MARK2
MAP/microtubule affinity-regulating kinase 2
chrX_+_37639306 3.492 CYBB
cytochrome b-245, beta polypeptide
chr14_+_21249209 3.489 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr10_-_72362441 3.483 PRF1
perforin 1 (pore forming protein)
chr12_-_111358353 3.464 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr3_+_10857867 3.458 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr5_+_113698304 3.441 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr2_-_183731279 3.415 NM_001463
FRZB
frizzled-related protein
chr14_-_106174914 3.401 IGHA1
immunoglobulin heavy constant alpha 1
chr18_+_72922725 3.387 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr20_-_23062786 3.380 CD93
CD93 molecule
chr17_-_61950997 3.322 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr6_-_46293628 3.318 NM_005822
RCAN2
regulator of calcineurin 2
chr1_+_150230168 3.316 NM_012113
CA14
carbonic anhydrase XIV
chr17_+_56315786 3.291 NM_001160102
NM_006151
LPO

lactoperoxidase

chr2_+_219724545 3.284 NM_006522
WNT6
wingless-type MMTV integration site family, member 6
chr3_-_12941547 3.272 IQSEC1
IQ motif and Sec7 domain 1
chr14_-_24036939 3.253 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr1_+_45266048 3.242 PLK3
polo-like kinase 3
chr11_+_45907198 3.226 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr19_+_48867650 3.196 NM_012451
SYNGR4
synaptogyrin 4
chr6_-_97731051 3.194 NM_198468
MMS22L
MMS22-like, DNA repair protein
chr3_-_187463227 3.176 BCL6
B-cell CLL/lymphoma 6
chr10_+_11047274 3.160 CELF2
CUGBP, Elav-like family member 2
chr14_+_24584009 3.142 DCAF11
DDB1 and CUL4 associated factor 11
chr1_+_174769034 3.135 NM_001243765
RABGAP1L
RAB GTPase activating protein 1-like
chr20_+_17207669 3.119 PCSK2
proprotein convertase subtilisin/kexin type 2
chr16_+_2587989 3.115 PDPK1
3-phosphoinositide dependent protein kinase-1
chr7_+_27282163 3.025 NM_001989
EVX1
even-skipped homeobox 1
chr5_-_112630557 3.009 NM_002387
MCC
mutated in colorectal cancers
chr11_-_114466397 2.998 FAM55D
family with sequence similarity 55, member D
chr14_+_24583979 2.974 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr1_-_240775388 2.972 GREM2
gremlin 2
chr10_-_126432893 2.965 NM_014661
FAM53B
family with sequence similarity 53, member B
chr14_-_106774311 2.961 IGHA1
immunoglobulin heavy constant alpha 1
chr2_-_197036262 2.943 STK17B
serine/threonine kinase 17b
chrX_+_152770083 2.918 BGN
biglycan
chrX_+_16804531 2.883 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr10_+_11047253 2.877 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr7_+_5920426 2.870 NM_001097622
OCM
oncomodulin
chr17_-_61988614 2.852 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chrX_-_135749436 2.845 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr16_+_1583657 2.823 TMEM204
transmembrane protein 204
chr6_+_42788793 2.813 NM_015349
KIAA0240
KIAA0240
chr12_+_54943176 2.792 NM_000924
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr15_-_35087748 2.790 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr3_+_50654868 2.786 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chrX_-_107019001 2.784 NM_198057
TSC22D3
TSC22 domain family, member 3
chr1_+_150245182 2.736 NM_024579
C1orf54
chromosome 1 open reading frame 54
chr19_+_55591759 2.699 NM_017729
EPS8L1
EPS8-like 1
chr1_+_27114409 2.699 NM_017837
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr14_-_106110894 2.697 IGHG2
immunoglobulin heavy constant gamma 2 (G2m marker)
chr21_+_40823779 2.693 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr17_+_38230678 2.691 THRA
thyroid hormone receptor, alpha
chr8_-_82395401 2.663 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr19_-_46285746 2.662 DMPK
dystrophia myotonica-protein kinase
chr7_-_64023444 2.656


chr2_-_25468909 2.650 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr20_+_55904814 2.643 NM_012444
NM_198265
SPO11

SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)

chr1_-_46598250 2.633 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr3_+_52811601 2.628 NM_002215
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr19_-_39390168 2.623 NM_012237
NM_001193286
NM_030593
SIRT2


sirtuin 2


chr1_-_169555624 2.621 F5
coagulation factor V (proaccelerin, labile factor)
chr5_+_74807580 2.597 NM_016218
POLK
polymerase (DNA directed) kappa
chr12_-_45270071 2.596 NELL2
NEL-like 2 (chicken)
chr10_+_118305427 2.593 NM_000936
PNLIP
pancreatic lipase
chr1_+_203444955 2.569 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr16_-_18937722 2.557 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr1_+_151584514 2.555 NM_030918
SNX27
sorting nexin family member 27
chr16_+_72097124 2.555 NM_020995
HPR
haptoglobin-related protein
chr1_-_12677347 2.548 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr1_-_156399183 2.546 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr19_+_50713823 2.534 MYH14
myosin, heavy chain 14, non-muscle
chr9_-_117267710 2.515 NM_001173425
NM_015404
DFNB31

deafness, autosomal recessive 31

chr2_+_16081945 2.510 MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr3_-_46505077 2.494 NM_001199149
LTF
lactotransferrin
chr14_-_23288912 2.486 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_25799024 2.482 NM_014238
KSR1
kinase suppressor of ras 1
chr15_-_58357848 2.481 ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr16_+_2653350 2.455 LOC652276
potassium channel tetramerisation domain containing 5 pseudogene
chr17_+_34640030 2.447 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr7_-_99766191 2.447 GAL3ST4
galactose-3-O-sulfotransferase 4
chr1_+_28199053 2.389 NM_001039477
NM_001105556
NM_004848
C1orf38


chromosome 1 open reading frame 38


chr10_-_123356158 2.387 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr11_-_46408105 2.381 NM_000741
CHRM4
cholinergic receptor, muscarinic 4
chr12_+_54943358 2.366 PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr1_+_17846818 2.337 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr16_+_31271277 2.317 NM_000632
NM_001145808
ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

chr11_-_62521533 2.315 NM_024784
ZBTB3
zinc finger and BTB domain containing 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.57 4.95e-15 GO:0023052 signaling
1.43 8.93e-14 GO:0032501 multicellular organismal process
1.76 6.53e-13 GO:0065008 regulation of biological quality
1.35 1.12e-11 GO:0050896 response to stimulus
1.28 1.33e-11 GO:0065007 biological regulation
2.09 1.14e-10 GO:0007154 cell communication
2.28 1.78e-10 GO:0007267 cell-cell signaling
1.49 3.54e-09 GO:0007165 signal transduction
1.16 4.74e-09 GO:0009987 cellular process
1.41 1.62e-08 GO:0051716 cellular response to stimulus
1.42 9.99e-08 GO:0032502 developmental process
1.65 3.16e-07 GO:0007166 cell surface receptor linked signaling pathway
1.42 9.42e-07 GO:0007275 multicellular organismal development
1.94 1.16e-06 GO:0009611 response to wounding
1.24 2.03e-06 GO:0050789 regulation of biological process
1.41 2.45e-06 GO:0051179 localization
1.24 2.99e-06 GO:0050794 regulation of cellular process
2.28 5.09e-06 GO:0019226 transmission of nerve impulse
2.28 5.09e-06 GO:0035637 multicellular organismal signaling
1.46 5.38e-06 GO:0048731 system development
1.59 5.89e-06 GO:0048583 regulation of response to stimulus
1.52 7.13e-06 GO:0042221 response to chemical stimulus
1.74 8.56e-06 GO:0002376 immune system process
2.35 8.63e-06 GO:0007268 synaptic transmission
2.14 1.31e-05 GO:0050878 regulation of body fluid levels
1.71 1.90e-05 GO:0051239 regulation of multicellular organismal process
1.41 3.06e-05 GO:0048856 anatomical structure development
1.83 3.66e-05 GO:0070887 cellular response to chemical stimulus
1.92 6.28e-05 GO:0006955 immune response
1.40 1.01e-04 GO:0006810 transport
1.60 1.71e-04 GO:0009653 anatomical structure morphogenesis
1.45 2.17e-04 GO:0006950 response to stress
1.39 2.18e-04 GO:0051234 establishment of localization
1.56 2.83e-04 GO:0023051 regulation of signaling
2.08 5.19e-04 GO:0007596 blood coagulation
2.08 5.19e-04 GO:0050817 coagulation
1.97 6.43e-04 GO:0042060 wound healing
2.07 6.46e-04 GO:0007599 hemostasis
1.72 9.26e-04 GO:0032879 regulation of localization
1.49 1.12e-03 GO:0048513 organ development
1.57 1.67e-03 GO:0009966 regulation of signal transduction
1.88 1.70e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.47 1.83e-03 GO:0008361 regulation of cell size
2.19 2.30e-03 GO:0090066 regulation of anatomical structure size
1.73 3.22e-03 GO:0040011 locomotion
1.72 3.39e-03 GO:0006811 ion transport
1.93 3.81e-03 GO:0006928 cellular component movement
1.48 4.47e-03 GO:0003008 system process
1.64 4.64e-03 GO:0010646 regulation of cell communication
2.05 4.85e-03 GO:0032583 regulation of gene-specific transcription
3.89 5.99e-03 GO:0016049 cell growth
1.82 6.08e-03 GO:0042325 regulation of phosphorylation
3.07 6.12e-03 GO:0001763 morphogenesis of a branching structure
2.20 6.14e-03 GO:0044057 regulation of system process
2.63 6.71e-03 GO:0048732 gland development
1.73 6.79e-03 GO:0006952 defense response
2.06 7.17e-03 GO:0016477 cell migration
1.38 7.48e-03 GO:0048522 positive regulation of cellular process
1.79 8.16e-03 GO:0019220 regulation of phosphate metabolic process
1.79 8.16e-03 GO:0051174 regulation of phosphorus metabolic process
1.99 8.55e-03 GO:0048870 cell motility
1.99 8.55e-03 GO:0051674 localization of cell
1.52 8.66e-03 GO:0065009 regulation of molecular function
14.17 1.06e-02 GO:0002456 T cell mediated immunity
2.17 1.20e-02 GO:0032535 regulation of cellular component size
2.19 1.23e-02 GO:0051046 regulation of secretion
3.48 1.45e-02 GO:0030879 mammary gland development
2.76 1.50e-02 GO:0050900 leukocyte migration
1.41 1.55e-02 GO:0030154 cell differentiation
1.89 1.93e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
3.14 2.10e-02 GO:0061138 morphogenesis of a branching epithelium
1.96 2.31e-02 GO:0051094 positive regulation of developmental process
3.70 2.39e-02 GO:0050708 regulation of protein secretion
1.78 2.56e-02 GO:0001932 regulation of protein phosphorylation
2.74 2.69e-02 GO:0042445 hormone metabolic process
1.64 2.69e-02 GO:0050793 regulation of developmental process
1.39 2.94e-02 GO:0048869 cellular developmental process
1.52 3.29e-02 GO:0010033 response to organic substance
2.46 3.73e-02 GO:0010817 regulation of hormone levels
1.79 3.96e-02 GO:0009887 organ morphogenesis
3.54 4.12e-02 GO:0022612 gland morphogenesis
1.74 4.18e-02 GO:0009719 response to endogenous stimulus
2.07 4.53e-02 GO:0043434 response to peptide hormone stimulus
1.75 4.57e-02 GO:0071310 cellular response to organic substance

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.72 3.52e-13 GO:0044459 plasma membrane part
1.97 4.98e-12 GO:0005887 integral to plasma membrane
1.93 2.14e-11 GO:0031226 intrinsic to plasma membrane
1.38 1.99e-08 GO:0005886 plasma membrane
1.37 7.06e-08 GO:0071944 cell periphery
1.54 9.10e-07 GO:0005576 extracellular region
1.90 4.77e-06 GO:0005615 extracellular space
1.72 2.84e-05 GO:0044421 extracellular region part
2.19 1.32e-04 GO:0009986 cell surface
1.74 4.69e-04 GO:0031982 vesicle
1.76 5.13e-04 GO:0031410 cytoplasmic vesicle
2.55 7.97e-04 GO:0030141 stored secretory granule
1.74 1.54e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.73 1.55e-03 GO:0031988 membrane-bounded vesicle
1.62 9.98e-03 GO:0005626 insoluble fraction
1.53 1.03e-02 GO:0000267 cell fraction
2.29 1.34e-02 GO:0034702 ion channel complex
1.60 1.91e-02 GO:0005624 membrane fraction
2.15 3.03e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.85 3.57e-07 GO:0005102 receptor binding
2.39 7.73e-07 GO:0015267 channel activity
2.38 8.49e-07 GO:0022803 passive transmembrane transporter activity
1.88 2.46e-06 GO:0022891 substrate-specific transmembrane transporter activity
1.84 2.84e-06 GO:0022857 transmembrane transporter activity
1.71 6.34e-06 GO:0005215 transporter activity
2.29 1.36e-05 GO:0022838 substrate-specific channel activity
1.74 3.17e-05 GO:0022892 substrate-specific transporter activity
1.88 3.35e-05 GO:0015075 ion transmembrane transporter activity
2.23 5.42e-05 GO:0005216 ion channel activity
2.37 1.09e-04 GO:0022836 gated channel activity
1.94 3.67e-04 GO:0008324 cation transmembrane transporter activity
1.96 4.33e-03 GO:0008289 lipid binding
3.36 5.85e-03 GO:0015294 solute:cation symporter activity
4.10 7.07e-03 GO:0004879 ligand-dependent nuclear receptor activity
2.86 7.95e-03 GO:0015276 ligand-gated ion channel activity
2.86 7.95e-03 GO:0022834 ligand-gated channel activity
2.19 9.43e-03 GO:0005261 cation channel activity
1.16 1.33e-02 GO:0005515 protein binding
4.00 1.97e-02 GO:0003707 steroid hormone receptor activity
5.67 2.86e-02 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
4.07 3.58e-02 GO:0001948 glycoprotein binding