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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: ESRRA.p2

Z-value: 3.238

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_+_145149985	82.272		CYC1	cytochrome c-1
chr2_-_176046120	81.835	NM_001002258 NM_001190329 NM_001689	ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr10_+_81107259	80.838		PPIF	peptidylprolyl isomerase F
chr10_+_81107242	80.779		PPIF	peptidylprolyl isomerase F
chr5_+_218428	50.854		SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chrX_+_118602391	47.372		SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr5_+_218441	45.038		SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr8_+_145149936	42.879	NM_001916	CYC1	cytochrome c-1
chr3_-_131221649	42.847	NM_007208	MRPL3	mitochondrial ribosomal protein L3
chr8_+_145149978	41.774		CYC1	cytochrome c-1
chr10_+_81107219	40.200	NM_005729	PPIF	peptidylprolyl isomerase F
chr10_+_81107228	40.019		PPIF	peptidylprolyl isomerase F
chr12_-_21810720	37.995	NM_001174097	LDHB	lactate dehydrogenase B
chr2_-_44223131	37.915	NM_133259	LRPPRC	leucine-rich PPR-motif containing
chr12_-_21810779	37.865	NM_002300	LDHB	lactate dehydrogenase B
chr12_-_21810733	37.493		LDHB	lactate dehydrogenase B
chr12_-_21810754	37.309		LDHB	lactate dehydrogenase B
chr19_-_13044459	36.909		FARSA	phenylalanyl-tRNA synthetase, alpha subunit
chr16_+_21964700	36.800		UQCRC2	ubiquinol-cytochrome c reductase core protein II
chr20_+_3776905	36.716		CDC25B	cell division cycle 25 homolog B (S. pombe)
chr12_-_21810769	36.692		LDHB	lactate dehydrogenase B
chr16_+_21964677	36.637		UQCRC2	ubiquinol-cytochrome c reductase core protein II
chr20_+_3776385	36.278	NM_004358 NM_021872 NM_021873	CDC25B	cell division cycle 25 homolog B (S. pombe)
chr10_-_120938276	35.594		PRDX3	peroxiredoxin 3
chr16_+_21964608	35.355	NM_003366	UQCRC2	ubiquinol-cytochrome c reductase core protein II
chr7_-_30029904	35.022	NM_001145514	SCRN1	secernin 1
chr12_+_6976694	35.021		TPI1	triosephosphate isomerase 1
chr18_-_43678233	34.996		ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr12_+_6976583	33.863	NM_001159287 NM_000365	TPI1	triosephosphate isomerase 1
chr1_+_46769336	33.770	NM_006004	UQCRH	ubiquinol-cytochrome c reductase hinge protein
chr2_-_44223112	32.950		LRPPRC	leucine-rich PPR-motif containing
chr15_+_40453263	32.041		BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr14_-_104387837	32.023		C14orf2	chromosome 14 open reading frame 2
chr10_+_99185977	31.991		PGAM1	phosphoglycerate mutase 1 (brain)
chr5_+_218355	31.846	NM_004168	SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr8_+_110346549	31.746	NM_001193557 NM_020189	ENY2	enhancer of yellow 2 homolog (Drosophila)
chr11_+_65769886	30.606		BANF1	barrier to autointegration factor 1
chr8_-_131028674	30.477		FAM49B	family with sequence similarity 49, member B
chr10_-_120938337	30.397	NM_006793 NM_014098	PRDX3	peroxiredoxin 3
chr11_+_65769956	30.276		BANF1	barrier to autointegration factor 1
chr5_+_218447	30.134		SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr9_-_130889993	29.914		PTGES2	prostaglandin E synthase 2
chrX_-_134156488	29.859	NM_001078173	FAM127C	family with sequence similarity 127, member C
chr2_+_198365012	29.809		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr16_-_81040439	29.718	NM_020188	C16orf61	chromosome 16 open reading frame 61
chr3_+_179322572	29.661	NM_001199957 NM_001199958 NM_002492	NDUFB5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr12_+_120875891	29.309	NM_004373	COX6A1	cytochrome c oxidase subunit VIa polypeptide 1
chr3_-_42845911	29.290	NM_001099668	HIGD1A	HIG1 hypoxia inducible domain family, member 1A
chr2_-_44223039	29.226		LRPPRC	leucine-rich PPR-motif containing
chr7_-_30029284	29.106	NM_001145515 NM_014766 NM_001145513	SCRN1	secernin 1
chr22_+_20105145	28.847		RANBP1	RAN binding protein 1
chr8_-_100905910	28.618		COX6C	cytochrome c oxidase subunit VIc
chr11_-_57298180	28.593	NM_012456	TIMM10	translocase of inner mitochondrial membrane 10 homolog (yeast)
chr4_-_74088773	28.442		ANKRD17	ankyrin repeat domain 17
chr12_-_54070108	28.403	NM_005176	ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr5_-_140027167	27.829		NDUFA2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr3_-_48647085	27.795	NM_003365	UQCRC1	ubiquinol-cytochrome c reductase core protein I
chr1_-_17380486	27.456	NM_003000	SDHB	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr3_-_42845946	27.231	NM_001099669 NM_014056	HIGD1A	HIG1 hypoxia inducible domain family, member 1A
chr1_-_205719340	27.108	NM_022731	NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr18_-_43678195	26.987		ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr19_-_39826676	26.946	NM_004877	GMFG	glia maturation factor, gamma
chr3_-_48647052	26.869		UQCRC1	ubiquinol-cytochrome c reductase core protein I
chr16_+_4674829	26.796		MGRN1	mahogunin, ring finger 1
chr16_+_4674819	26.749	NM_001142289 NM_001142290 NM_001142291 NM_015246	MGRN1	mahogunin, ring finger 1
chr1_+_161172174	26.725		NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr1_+_161172163	26.704		NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr2_+_198365113	26.638		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr10_+_99186012	26.408		PGAM1	phosphoglycerate mutase 1 (brain)
chr15_+_78441733	26.235		IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha
chr10_-_75012241	26.186	NM_016065	MRPS16	mitochondrial ribosomal protein S16
chr18_-_43678230	25.722		ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr19_-_2328566	25.716	NM_016199	LSM7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_47799447	25.648	NM_001136140 NM_016308	CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr11_+_34938112	25.506		PDHX	pyruvate dehydrogenase complex, component X
chr9_+_130965666	25.254		DNM1	dynamin 1
chr18_-_43678251	24.860		ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr1_-_246580710	24.827	NM_022743	SMYD3	SET and MYND domain containing 3
chr16_-_85832900	24.775	NM_001142288 NM_006067	COX4NB	COX4 neighbor
chr6_+_34206567	24.754	NM_145905	HMGA1	high mobility group AT-hook 1
chr20_-_2641476	24.565		IDH3B	isocitrate dehydrogenase 3 (NAD+) beta
chr1_+_236558715	24.300	NM_080738	EDARADD	EDAR-associated death domain
chr2_+_109237679	24.300	NM_001193484	LIMS1	LIM and senescent cell antigen-like domains 1
chr8_-_131028833	24.299		FAM49B	family with sequence similarity 49, member B
chr8_-_100905865	24.265		COX6C	cytochrome c oxidase subunit VIc
chr12_-_102512277	24.113	NM_024057	NUP37	nucleoporin 37kDa
chr22_+_20105095	24.032		RANBP1	RAN binding protein 1
chr2_-_198364522	24.021		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr19_-_3062911	24.000	NM_198969	AES	amino-terminal enhancer of split
chr5_-_137911039	23.987		HSPA9	heat shock 70kDa protein 9 (mortalin)
chr12_-_57039785	23.982	NM_001686	ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr22_+_20105076	23.815		RANBP1	RAN binding protein 1
chrX_+_47053192	23.739	NM_003334	UBA1	ubiquitin-like modifier activating enzyme 1
chr12_+_98987674	23.642		SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chrX_-_129299680	23.488		AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr7_+_44836273	23.357		PPIA	peptidylprolyl isomerase A (cyclophilin A)
chr22_-_24316602	23.245	NM_001084392	DDT	D-dopachrome tautomerase
chr22_+_24309025	23.219	NM_001084393	DDTL	D-dopachrome tautomerase-like
chr4_-_7069755	23.188	NM_025196	GRPEL1	GrpE-like 1, mitochondrial (E. coli)
chr10_+_99186040	23.184		PGAM1	phosphoglycerate mutase 1 (brain)
chr10_+_99186042	23.049		PGAM1	phosphoglycerate mutase 1 (brain)
chr20_-_62130390	22.940	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr5_-_137911005	22.750		HSPA9	heat shock 70kDa protein 9 (mortalin)
chr19_+_1383898	22.605		NDUFS7	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chrX_+_47053227	22.487		UBA1	ubiquitin-like modifier activating enzyme 1
chr2_-_198364560	22.275		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr6_-_2840683	22.056		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr16_-_2723374	22.053		ERVK13-1	endogenous retrovirus group K13, member 1
chrX_+_47053213	22.019		UBA1	ubiquitin-like modifier activating enzyme 1
chr12_-_54069856	21.951		ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr19_+_1383904	21.899		NDUFS7	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chrX_-_129299629	21.831		AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr1_+_47799488	21.791		CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr15_-_41694619	21.619	NM_016013	NDUFAF1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
chrX_+_47053271	21.452		UBA1	ubiquitin-like modifier activating enzyme 1
chr2_-_198364623	21.390	NM_002156	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr9_+_17578952	21.147	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr1_+_201924618	20.904	NM_006335	TIMM17A	translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr1_-_33502470	20.855		AK2	adenylate kinase 2
chr12_-_57039736	20.575		ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr3_+_195384941	20.534		SDHAP2	succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chrX_-_129299803	20.486	NM_001130847 NM_004208 NM_145812 NM_145813	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr1_-_33502452	20.453		AK2	adenylate kinase 2
chr10_+_99186017	20.399	NM_002629	PGAM1	phosphoglycerate mutase 1 (brain)
chrX_+_47053302	20.369		UBA1	ubiquitin-like modifier activating enzyme 1
chr7_+_56032065	20.327	NM_001202469 NM_001483	GBAS	glioblastoma amplified sequence
chr19_+_1383877	20.322	NM_024407	NDUFS7	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chrX_+_47053234	20.277		UBA1	ubiquitin-like modifier activating enzyme 1
chr19_-_13044528	20.260	NM_004461	FARSA	phenylalanyl-tRNA synthetase, alpha subunit
chr16_-_47177902	20.209	NM_001201477 NM_018092	NETO2	neuropilin (NRP) and tolloid (TLL)-like 2
chr15_+_66694216	20.114		MAP2K1	mitogen-activated protein kinase kinase 1
chr16_+_81040515	20.018		CENPN	centromere protein N
chr9_-_130889965	20.001		PTGES2	prostaglandin E synthase 2
chr11_+_67798077	19.935	NM_002496	NDUFS8	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chrX_+_153657119	19.656		ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1
chr19_-_3062191	19.424	NM_001130 NM_198970	AES	amino-terminal enhancer of split
chr16_-_47177832	19.388		NETO2	neuropilin (NRP) and tolloid (TLL)-like 2
chr1_+_155179005	19.373		MTX1	metaxin 1
chr22_-_43036606	19.279	NM_001165877	ATP5L2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr1_-_33502464	19.187		AK2	adenylate kinase 2
chr17_+_30469567	19.031		RHOT1	ras homolog gene family, member T1
chr3_-_113465101	18.927	NM_025146	NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr8_+_86376130	18.788	NM_000067	CA2	carbonic anhydrase II
chr17_+_30469541	18.750		RHOT1	ras homolog gene family, member T1
chr3_+_184038050	18.709	NM_004953	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr8_-_131028646	18.520		FAM49B	family with sequence similarity 49, member B
chr1_-_67896098	18.476	NM_001018067 NM_001018068 NM_001018069 NM_015640	SERBP1	SERPINE1 mRNA binding protein 1
chr10_+_99186004	18.318		PGAM1	phosphoglycerate mutase 1 (brain)
chr1_+_161172125	18.302		NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr15_+_43885251	18.167	NM_020990	CKMT1B CKMT1A	creatine kinase, mitochondrial 1B creatine kinase, mitochondrial 1A
chr16_-_28222700	17.961		XPO6	exportin 6
chr1_-_33502428	17.960		AK2	adenylate kinase 2
chr13_-_24007822	17.906	NM_014363	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)
chr11_+_73498913	17.802	NM_016055	MRPL48	mitochondrial ribosomal protein L48
chr22_-_47134130	17.769	NM_022766	CERK	ceramide kinase
chr22_-_36681757	17.744		MYH9	myosin, heavy chain 9, non-muscle
chr10_+_62538088	17.712	NM_001170406 NM_001170407 NM_001786 NM_033379	CDK1	cyclin-dependent kinase 1
chr20_+_57466248	17.661	NM_000516 NM_001077488 NM_001077489 NM_080426	GNAS	GNAS complex locus
chr20_-_31989303	17.631		CDK5RAP1	CDK5 regulatory subunit associated protein 1
chr6_-_97345760	17.503	NM_014165	NDUFAF4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
chr7_+_99686609	17.431		COPS6	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
chr14_+_57735605	17.320	NM_018229	MUDENG	MU-2/AP1M2 domain containing, death-inducing
chr17_+_79670495	17.207		MRPL12	mitochondrial ribosomal protein L12
chr19_-_39826625	17.115		GMFG	glia maturation factor, gamma
chr3_-_10028512	16.972	NM_018447	TMEM111	transmembrane protein 111
chr1_+_228270802	16.946	NM_001024227 NM_001024228	ARF1	ADP-ribosylation factor 1
chr15_+_78441678	16.895	NM_005530	IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha
chr22_-_50524357	16.831	NM_015166	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr1_+_32757711	16.735		HDAC1	histone deacetylase 1
chr3_-_195808934	16.598		TFRC	transferrin receptor (p90, CD71)
chr10_-_126107493	16.539	NM_000274 NM_001171814	OAT	ornithine aminotransferase
chr3_-_195808958	16.534	NM_003234	TFRC	transferrin receptor (p90, CD71)
chr15_-_83735892	16.527		BTBD1	BTB (POZ) domain containing 1
chr17_+_79670396	16.359	NM_002949	MRPL12	mitochondrial ribosomal protein L12
chr1_+_32757702	16.162		HDAC1	histone deacetylase 1
chr14_-_105261850	16.152		AKT1	v-akt murine thymoma viral oncogene homolog 1
chr9_-_130890026	16.096		PTGES2	prostaglandin E synthase 2
chr2_+_26467615	15.991	NM_000183	HADHB	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
chr18_-_43678273	15.968	NM_004046	ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr17_+_46970128	15.963	NM_001002027 NM_005175	ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr19_+_54606141	15.896	NM_004542	NDUFA3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr9_-_130890007	15.838		PTGES2	prostaglandin E synthase 2
chrY_-_1460901	15.767	NM_001636	SLC25A6	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr5_+_85913762	15.563	NM_001867	COX7C	cytochrome c oxidase subunit VIIc
chr10_-_118765087	15.495	NM_001127211 NM_018330	KIAA1598	KIAA1598
chr14_+_100150596	15.486	NM_006668	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1
chrX_-_109683457	15.474	NM_001171689	AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr6_-_97345747	15.350		NDUFAF4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
chr20_-_31989330	15.283	NM_016082 NM_016408	CDK5RAP1	CDK5 regulatory subunit associated protein 1
chr1_+_32757707	15.247	NM_004964	HDAC1	histone deacetylase 1
chr1_+_165600433	15.183		MGST3	microsomal glutathione S-transferase 3
chr3_-_10028344	15.137		TMEM111	transmembrane protein 111
chr9_+_130965668	15.069		DNM1	dynamin 1
chr1_-_27732069	15.006		WASF2	WAS protein family, member 2
chr22_+_44351260	14.991	NM_015380	SAMM50	sorting and assembly machinery component 50 homolog (S. cerevisiae)
chr1_+_6094342	14.942	NM_001199860	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr22_-_42486740	14.850		NDUFA6	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
chr1_-_67896081	14.691		SERBP1	SERPINE1 mRNA binding protein 1
chr19_+_8509802	14.676	NM_005968 NM_031203	HNRNPM	heterogeneous nuclear ribonucleoprotein M
chr11_+_67033889	14.636	NM_001619	ADRBK1	adrenergic, beta, receptor kinase 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
8.89	4.14e-24	GO:0045333	cellular respiration
10.31	2.19e-23	GO:0022904	respiratory electron transport chain
7.41	6.83e-18	GO:0022900	electron transport chain
4.98	8.16e-17	GO:0015980	energy derivation by oxidation of organic compounds
4.10	6.19e-16	GO:0006091	generation of precursor metabolites and energy
1.26	6.04e-15	GO:0009987	cellular process
1.48	4.63e-14	GO:0044237	cellular metabolic process
10.51	5.56e-12	GO:0006119	oxidative phosphorylation
11.09	9.70e-12	GO:0042773	ATP synthesis coupled electron transport
11.09	9.70e-12	GO:0042775	mitochondrial ATP synthesis coupled electron transport
2.55	5.81e-11	GO:0055114	oxidation-reduction process
1.38	6.64e-11	GO:0008152	metabolic process
1.74	7.10e-11	GO:0006810	transport
1.72	2.74e-10	GO:0051234	establishment of localization
1.62	1.41e-09	GO:0051179	localization
7.04	6.10e-09	GO:0006839	mitochondrial transport
10.54	2.42e-08	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
10.68	1.08e-07	GO:0009060	aerobic respiration
2.32	1.44e-06	GO:0046907	intracellular transport
9.86	1.79e-06	GO:0070585	protein localization in mitochondrion
2.06	2.79e-06	GO:0051649	establishment of localization in cell
1.97	3.49e-06	GO:0051641	cellular localization
13.55	7.67e-06	GO:0015985	energy coupled proton transport, down electrochemical gradient
13.55	7.67e-06	GO:0015986	ATP synthesis coupled proton transport
9.62	1.22e-05	GO:0006626	protein targeting to mitochondrion
9.32	1.80e-05	GO:0072655	establishment of protein localization in mitochondrion
1.85	2.56e-05	GO:0009056	catabolic process
4.31	2.83e-05	GO:0007005	mitochondrion organization
3.71	1.08e-04	GO:0006732	coenzyme metabolic process
10.17	1.69e-04	GO:0006099	tricarboxylic acid cycle
1.69	2.01e-04	GO:0044281	small molecule metabolic process
9.76	2.55e-04	GO:0046356	acetyl-CoA catabolic process
1.87	3.68e-04	GO:0044248	cellular catabolic process
1.29	4.03e-04	GO:0044238	primary metabolic process
2.30	6.97e-04	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
2.35	9.48e-04	GO:0006753	nucleoside phosphate metabolic process
2.35	9.48e-04	GO:0009117	nucleotide metabolic process
8.41	1.10e-03	GO:0009109	coenzyme catabolic process
3.84	1.74e-03	GO:0046034	ATP metabolic process
5.61	1.93e-03	GO:0015992	proton transport
11.16	2.23e-03	GO:0072384	organelle transport along microtubule
3.01	2.82e-03	GO:0051186	cofactor metabolic process
5.42	2.82e-03	GO:0006818	hydrogen transport
27.11	3.20e-03	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
2.08	4.55e-03	GO:0046483	heterocycle metabolic process
7.18	4.86e-03	GO:0006084	acetyl-CoA metabolic process
2.26	5.09e-03	GO:0044283	small molecule biosynthetic process
12.51	5.95e-03	GO:0042776	mitochondrial ATP synthesis coupled proton transport
6.97	6.33e-03	GO:0051187	cofactor catabolic process
2.55	7.20e-03	GO:0009259	ribonucleotide metabolic process
3.95	9.79e-03	GO:0009260	ribonucleotide biosynthetic process
2.56	1.03e-02	GO:0009150	purine ribonucleotide metabolic process
5.65	1.42e-02	GO:0006733	oxidoreduction coenzyme metabolic process
4.04	1.53e-02	GO:0009152	purine ribonucleotide biosynthetic process
2.28	1.77e-02	GO:0072521	purine-containing compound metabolic process
2.57	1.96e-02	GO:0009205	purine ribonucleoside triphosphate metabolic process
2.13	2.02e-02	GO:0044282	small molecule catabolic process
2.56	2.09e-02	GO:0009199	ribonucleoside triphosphate metabolic process
2.55	2.37e-02	GO:0009144	purine nucleoside triphosphate metabolic process
1.87	2.44e-02	GO:0055085	transmembrane transport
4.40	2.76e-02	GO:0009206	purine ribonucleoside triphosphate biosynthetic process
1.46	3.03e-02	GO:0044249	cellular biosynthetic process
5.81	3.17e-02	GO:0043648	dicarboxylic acid metabolic process
4.34	3.18e-02	GO:0009145	purine nucleoside triphosphate biosynthetic process
4.34	3.18e-02	GO:0009201	ribonucleoside triphosphate biosynthetic process
1.44	3.27e-02	GO:0009058	biosynthetic process
2.48	3.68e-02	GO:0009141	nucleoside triphosphate metabolic process
4.59	4.10e-02	GO:0006754	ATP biosynthetic process
4.23	4.18e-02	GO:0009142	nucleoside triphosphate biosynthetic process
7.59	4.26e-02	GO:0007006	mitochondrial membrane organization
18.07	4.53e-02	GO:0034643	establishment of mitochondrion localization, microtubule-mediated
18.07	4.53e-02	GO:0047497	mitochondrion transport along microtubule
18.07	4.53e-02	GO:0051654	establishment of mitochondrion localization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
4.43	1.44e-36	GO:0044429	mitochondrial part
3.19	2.44e-35	GO:0005739	mitochondrion
6.19	3.12e-32	GO:0005743	mitochondrial inner membrane
5.15	3.20e-32	GO:0031966	mitochondrial membrane
4.93	8.43e-31	GO:0005740	mitochondrial envelope
5.76	1.25e-30	GO:0019866	organelle inner membrane
1.50	7.24e-30	GO:0005737	cytoplasm
9.94	7.35e-30	GO:0044455	mitochondrial membrane part
3.71	3.91e-26	GO:0031975	envelope
3.73	4.67e-26	GO:0031967	organelle envelope
1.62	3.81e-24	GO:0044444	cytoplasmic part
11.09	2.65e-19	GO:0070469	respiratory chain
11.11	8.33e-18	GO:0005746	mitochondrial respiratory chain
1.26	6.26e-17	GO:0044424	intracellular part
1.23	3.42e-15	GO:0005622	intracellular
1.49	4.67e-13	GO:0044422	organelle part
1.48	1.71e-12	GO:0044446	intracellular organelle part
1.27	1.46e-11	GO:0043229	intracellular organelle
1.27	2.10e-11	GO:0043226	organelle
1.87	6.16e-11	GO:0031090	organelle membrane
1.29	2.94e-10	GO:0043231	intracellular membrane-bounded organelle
1.29	3.57e-10	GO:0043227	membrane-bounded organelle
3.80	3.87e-09	GO:0005759	mitochondrial matrix
1.56	9.72e-09	GO:0032991	macromolecular complex
9.73	1.64e-08	GO:0005747	mitochondrial respiratory chain complex I
9.73	1.64e-08	GO:0030964	NADH dehydrogenase complex
9.73	1.64e-08	GO:0045271	respiratory chain complex I
1.77	2.50e-08	GO:0005829	cytosol
1.57	5.17e-07	GO:0043234	protein complex
14.35	7.49e-07	GO:0005753	mitochondrial proton-transporting ATP synthase complex
12.84	2.66e-06	GO:0045259	proton-transporting ATP synthase complex
6.94	1.04e-04	GO:0016469	proton-transporting two-sector ATPase complex
14.79	3.22e-04	GO:0005744	mitochondrial inner membrane presequence translocase complex
1.07	4.25e-04	GO:0044464	cell part
1.07	4.34e-04	GO:0005623	cell
27.11	6.05e-04	GO:0005749	mitochondrial respiratory chain complex II
27.11	6.05e-04	GO:0045257	succinate dehydrogenase complex (ubiquinone)
27.11	6.05e-04	GO:0045273	respiratory chain complex II
27.11	6.05e-04	GO:0045281	succinate dehydrogenase complex
27.11	6.05e-04	GO:0045283	fumarate reductase complex
13.55	6.25e-04	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
7.18	9.18e-04	GO:0042645	mitochondrial nucleoid
6.97	1.20e-03	GO:0009295	nucleoid
1.50	1.23e-03	GO:0031974	membrane-enclosed lumen
3.62	2.91e-03	GO:0031968	organelle outer membrane
3.50	4.45e-03	GO:0019867	outer membrane
1.47	4.61e-03	GO:0070013	intracellular organelle lumen
3.80	5.99e-03	GO:0005741	mitochondrial outer membrane
1.46	6.91e-03	GO:0043233	organelle lumen
2.30	9.99e-03	GO:0048471	perinuclear region of cytoplasm
1.38	2.53e-02	GO:0043228	non-membrane-bounded organelle
1.38	2.53e-02	GO:0043232	intracellular non-membrane-bounded organelle
7.75	2.76e-02	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.38	2.20e-12	GO:0005515	protein binding
6.43	3.06e-10	GO:0015078	hydrogen ion transmembrane transporter activity
2.55	3.71e-09	GO:0016491	oxidoreductase activity
8.83	1.02e-07	GO:0016655	oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
9.53	1.52e-07	GO:0003954	NADH dehydrogenase activity
9.53	1.52e-07	GO:0008137	NADH dehydrogenase (ubiquinone) activity
9.53	1.52e-07	GO:0050136	NADH dehydrogenase (quinone) activity
1.38	3.54e-07	GO:0003824	catalytic activity
5.69	2.34e-06	GO:0016651	oxidoreductase activity, acting on NADH or NADPH
3.38	4.92e-06	GO:0022890	inorganic cation transmembrane transporter activity
3.72	7.01e-06	GO:0015077	monovalent inorganic cation transmembrane transporter activity
27.11	8.31e-04	GO:0000104	succinate dehydrogenase activity
1.13	8.52e-04	GO:0005488	binding
3.19	2.24e-03	GO:0009055	electron carrier activity
2.69	5.26e-03	GO:0048037	cofactor binding
7.91	8.22e-03	GO:0004129	cytochrome-c oxidase activity
7.91	8.22e-03	GO:0015002	heme-copper terminal oxidase activity
7.91	8.22e-03	GO:0016675	oxidoreductase activity, acting on a heme group of donors
7.91	8.22e-03	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
27.11	2.25e-02	GO:0004449	isocitrate dehydrogenase (NAD+) activity
15.49	2.66e-02	GO:0008121	ubiquinol-cytochrome-c reductase activity
15.49	2.66e-02	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors
15.49	2.66e-02	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
9.68	4.63e-02	GO:0046933	hydrogen ion transporting ATP synthase activity, rotational mechanism