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• Activity deltas table
• Regulatory interactions
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Motif ID: ETS1,2.p2

Z-value: 2.906

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr21_-_46340874	52.542	NM_000211	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr21_-_46340821	50.174		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr19_+_49838734	45.781		CD37	CD37 molecule
chr13_+_31287614	45.453	NM_001204406	ALOX5AP	arachidonate 5-lipoxygenase-activating protein
chr19_+_49838700	45.450		CD37	CD37 molecule
chr9_-_137809710	42.810	NM_002003	FCN1	ficolin (collagen/fibrinogen domain containing) 1
chr1_-_31230594	41.733		LAPTM5	lysosomal protein transmembrane 5
chr13_-_46756295	41.515		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr21_-_46340776	40.057		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_-_31230673	37.987	NM_006762	LAPTM5	lysosomal protein transmembrane 5
chr19_+_49838673	37.972	NM_001040031 NM_001774	CD37	CD37 molecule
chr6_+_31553955	36.079	NM_205838 NM_205839	LST1	leukocyte specific transcript 1
chr8_+_38034066	35.913	NM_001204878 NM_004874	BAG4	BCL2-associated athanogene 4
chr19_+_49838646	35.843		CD37	CD37 molecule
chr22_-_17680485	34.682	NM_177405	CECR1	cat eye syndrome chromosome region, candidate 1
chr9_-_88969323	33.823	NM_001185059 NM_001185074 NM_024617	ZCCHC6	zinc finger, CCHC domain containing 6
chr16_+_30194925	33.303		CORO1A	coronin, actin binding protein, 1A
chr5_-_149792276	32.319		CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr12_-_6798419	31.792		ZNF384	zinc finger protein 384
chr19_+_42387249	31.566	NM_004706 NM_198977	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1
chr1_+_111415721	31.438	NM_000560	CD53	CD53 molecule
chr11_+_46722564	31.021	NM_001184751	ZNF408	zinc finger protein 408
chr11_-_46722139	30.596		ARHGAP1	Rho GTPase activating protein 1
chr11_-_46722160	30.455		ARHGAP1	Rho GTPase activating protein 1
chr8_-_38034168	29.891		LSM1	LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_-_94856926	29.886	NM_001002235 NM_001002236 NM_001127700 NM_001127701 NM_001127702 NM_001127703 NM_001127704 NM_001127705 NM_001127706 NM_001127707	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr19_+_16435734	29.363		KLF2	Kruppel-like factor 2 (lung)
chr1_+_111415791	29.085		CD53	CD53 molecule
chr13_-_46756326	28.554	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_47759802	28.298		CCDC9	coiled-coil domain containing 9
chr19_+_47759730	27.621	NM_015603	CCDC9	coiled-coil domain containing 9
chr11_+_46722316	27.494	NM_024741	ZNF408	zinc finger protein 408
chr19_+_42387307	26.457		ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1
chr22_+_37257004	26.297	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr1_-_183559669	25.651	NM_000433 NM_001190789 NM_001190794	NCF2	neutrophil cytosolic factor 2
chr12_+_7055736	24.798	NM_080548	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chrY_+_2709596	24.763	NM_001008	RPS4Y1	ribosomal protein S4, Y-linked 1
chr10_-_72362513	24.674	NM_001083116 NM_005041	PRF1	perforin 1 (pore forming protein)
chr10_-_72362441	24.336		PRF1	perforin 1 (pore forming protein)
chrY_+_2709630	24.223		RPS4Y1	ribosomal protein S4, Y-linked 1
chr14_+_21249209	24.173	NM_005615	RNASE6	ribonuclease, RNase A family, k6
chr16_+_31085722	24.106	NM_014699	ZNF646	zinc finger protein 646
chr12_-_6798528	23.980	NM_133476	ZNF384	zinc finger protein 384
chr12_+_7055753	23.840		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr18_-_72264808	23.788		LOC400657	uncharacterized LOC400657
chr1_+_153330329	23.646	NM_002965	S100A9	S100 calcium binding protein A9
chr19_+_3178735	23.526	NM_003775	S1PR4	sphingosine-1-phosphate receptor 4
chrX_-_107019001	23.502	NM_198057	TSC22D3	TSC22 domain family, member 3
chr8_+_38034296	23.449		BAG4	BCL2-associated athanogene 4
chr1_-_161520412	23.174	NM_001127593 NM_001127595 NM_001127596	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr12_-_6798619	23.095	NM_001039920 NM_001135734	ZNF384	zinc finger protein 384
chr14_-_23284617	22.762		SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_-_37701385	22.514	NM_152279	ZNF585B	zinc finger protein 585B
chr16_+_30483959	22.237	NM_001114380 NM_002209	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr8_+_56792345	22.071	NM_001111097 NM_002350	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr8_+_56792392	21.766		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr17_-_79269082	21.690	NM_001037984 NM_138570	SLC38A10	solute carrier family 38, member 10
chr1_-_183559463	21.485		NCF2	neutrophil cytosolic factor 2
chr16_+_31085751	21.330		ZNF646	zinc finger protein 646
chr16_+_30484049	21.313		ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr5_-_149380121	21.239	NM_001243253	LOC728287 TIGD6	uncharacterized LOC728287 tigger transposable element derived 6
chr12_+_69742130	20.968	NM_000239	LYZ	lysozyme
chr7_-_5569200	20.929		ACTB	actin, beta
chr1_-_183560010	20.528	NM_001127651	NCF2	neutrophil cytosolic factor 2
chr19_-_56632644	20.188	NM_001002836	ZNF787	zinc finger protein 787
chr19_-_10450262	20.123	NM_002162	ICAM3	intercellular adhesion molecule 3
chr12_+_69742140	19.463		LYZ	lysozyme
chr5_-_130970851	19.296		RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6
chr16_-_31085503	19.242	NM_024706	ZNF668	zinc finger protein 668
chr1_-_27952591	19.135	NM_001042747	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr3_-_121379757	19.116	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr18_-_72265038	18.952		LOC400657	uncharacterized LOC400657
chr8_+_56792399	18.871		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_-_52831817	18.846	NM_032449	CC2D1B	coiled-coil and C2 domain containing 1B
chr2_+_69001932	18.553	NM_001166276 NM_014882	ARHGAP25	Rho GTPase activating protein 25
chr5_-_149792370	18.407	NM_001025158 NM_001025159 NM_004355	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr4_+_2813966	18.373		SH3BP2	SH3-domain binding protein 2
chrX_+_128913881	18.179	NM_018990	SASH3	SAM and SH3 domain containing 3
chr22_+_37678565	17.744		CYTH4	cytohesin 4
chr16_+_29674564	17.694		SPN	sialophorin
chr14_+_105953531	17.690		CRIP1	cysteine-rich protein 1 (intestinal)
chrX_+_128913897	17.611		SASH3	SAM and SH3 domain containing 3
chr11_+_61197574	17.486	NM_017841	SDHAF2	succinate dehydrogenase complex assembly factor 2
chr15_-_40599872	17.429		PLCB2	phospholipase C, beta 2
chr22_-_31688329	17.414	NM_001135911 NM_052880	PIK3IP1	phosphoinositide-3-kinase interacting protein 1
chr16_-_31214054	17.373	NM_013258 NM_145182	PYCARD	PYD and CARD domain containing
chr19_+_39899749	17.337
chr3_-_121379701	17.079		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr10_-_88717319	16.929	NM_024756	MMRN2	multimerin 2
chr1_+_26644458	16.570		CD52	CD52 molecule
chr2_-_69870837	16.460		AAK1	AP2 associated kinase 1
chr1_-_161519817	16.417	NM_000569 NM_001127592	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr1_-_161601752	16.214	NM_000570	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr19_-_36505102	16.090		ALKBH6	alkB, alkylation repair homolog 6 (E. coli)
chr15_+_91427664	16.041	NM_001143785 NM_002005	FES	feline sarcoma oncogene
chr19_+_57752051	15.883	NM_001023563 NM_001145078	ZNF805	zinc finger protein 805
chr13_-_46756291	15.881		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr15_-_40600118	15.308	NM_004573	PLCB2	phospholipase C, beta 2
chr21_-_15918635	15.236	NM_022136	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr6_-_109776942	15.185		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chrX_-_107018889	15.177		TSC22D3	TSC22 domain family, member 3
chr11_-_64512925	15.159	NM_153819	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_+_85804613	15.087	NM_003761	VAMP8	vesicle-associated membrane protein 8 (endobrevin)
chr10_+_26727692	15.059		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr13_-_44453825	15.012	NM_144974	CCDC122	coiled-coil domain containing 122
chr2_+_113931549	14.986	NM_012455	PSD4	pleckstrin and Sec7 domain containing 4
chr22_-_21213069	14.970		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr19_+_48248798	14.947		GLTSCR2	glioma tumor suppressor candidate region gene 2
chr22_+_17565844	14.946	NM_014339	IL17RA	interleukin 17 receptor A
chr1_-_1590403	14.938		CDK11A CDK11B	cyclin-dependent kinase 11A cyclin-dependent kinase 11B
chr22_+_37678423	14.922	NM_013385	CYTH4	cytohesin 4
chrX_-_47489703	14.814	NM_002621	CFP	complement factor properdin
chr14_-_24711767	14.779	NM_001099274 NM_012461	TINF2	TERF1 (TRF1)-interacting nuclear factor 2
chr6_-_109776946	14.766		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr5_-_130970907	14.680	NM_001164386 NM_001164387 NM_001164388 NM_001164389 NM_001164390 NM_016340	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6
chr19_+_48248792	14.488	NM_015710	GLTSCR2	glioma tumor suppressor candidate region gene 2
chr19_-_36399120	14.422		TYROBP	TYRO protein tyrosine kinase binding protein
chr6_-_33267128	14.401	NM_001243738 NM_004761	RGL2	ral guanine nucleotide dissociation stimulator-like 2
chr18_+_11851388	14.148	NM_020412	CHMP1B	charged multivesicular body protein 1B
chr6_+_31554975	14.107	NM_001166538 NM_007161 NM_205840	LST1	leukocyte specific transcript 1
chr2_+_113931565	14.057		PSD4	pleckstrin and Sec7 domain containing 4
chr2_-_69870705	14.046		AAK1	AP2 associated kinase 1
chr21_-_44299605	13.986		WDR4	WD repeat domain 4
chr12_-_6233684	13.953	NM_000552	VWF	von Willebrand factor
chr1_+_150266261	13.929	NM_018997 NM_031901	MRPS21	mitochondrial ribosomal protein S21
chr22_-_37545944	13.894	NM_000878	IL2RB	interleukin 2 receptor, beta
chr10_+_26727651	13.887		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr13_+_31191829	13.869	NM_005800	USPL1	ubiquitin specific peptidase like 1
chr14_-_24036532	13.848		AP1G2	adaptor-related protein complex 1, gamma 2 subunit
chr12_-_51717835	13.768		BIN2	bridging integrator 2
chr9_+_77703412	13.721		OSTF1	osteoclast stimulating factor 1
chr19_+_16999871	13.661		F2RL3	coagulation factor II (thrombin) receptor-like 3
chr7_-_102105161	13.616		ALKBH4	alkB, alkylation repair homolog 4 (E. coli)
chr6_-_133084585	13.525	NM_078488	VNN2	vanin 2
chr12_+_54892567	13.518	NM_001184976	NCKAP1L	NCK-associated protein 1-like
chr3_+_47324329	13.501	NM_025010	KLHL18	kelch-like 18 (Drosophila)
chr15_+_81589240	13.452	NM_004513	IL16	interleukin 16
chr12_+_7060433	13.376	NM_002831 NM_080549	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr2_+_68961912	13.372	NM_001007231 NM_001166277	ARHGAP25	Rho GTPase activating protein 25
chr14_+_69865380	13.328	NM_001252148 NM_001252150 NM_018375	SLC39A9	solute carrier family 39 (zinc transporter), member 9
chr15_-_40600025	13.276		PLCB2	phospholipase C, beta 2
chr7_+_108210188	13.197	NM_012328	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr2_+_103035148	13.190	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr7_+_108210291	13.185		DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr20_-_23066828	13.150	NM_012072	CD93	CD93 molecule
chr14_-_23284565	13.135		SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr7_+_150264457	13.116	NM_018326	GIMAP4	GTPase, IMAP family member 4
chr11_-_67771527	13.095	NM_030930	UNC93B1	unc-93 homolog B1 (C. elegans)
chr6_-_109777171	13.048	NM_001159291 NM_022765	MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr14_+_69865095	12.984	NM_001252151 NM_001252152	SLC39A9	solute carrier family 39 (zinc transporter), member 9
chr12_-_51717905	12.874	NM_016293	BIN2	bridging integrator 2
chr7_+_150434435	12.742	NM_018384	GIMAP5	GTPase, IMAP family member 5
chr6_+_31554475	12.730	NM_205837	LST1	leukocyte specific transcript 1
chr16_+_29465821	12.641	NM_001014999 NM_001015000 NM_024044 NM_178044	SLX1A-SULT1A3 SLX1A SLX1B	SLX1A-SULT1A3 readthrough SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr20_+_42839599	12.640		LOC100505783	uncharacterized LOC100505783
chr12_-_15114495	12.609	NM_001175	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr2_-_96811138	12.609	NM_004418	DUSP2	dual specificity phosphatase 2
chr2_+_17935124	12.593	NM_182625	GEN1	Gen endonuclease homolog 1 (Drosophila)
chr1_+_24882565	12.542	NM_001010980	C1orf130	chromosome 1 open reading frame 130
chr22_-_37640287	12.536	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_+_16296211	12.529	NM_014077	FAM32A	family with sequence similarity 32, member A
chr11_+_5710816	12.507	NM_001199573 NM_006074	TRIM22	tripartite motif containing 22
chr2_+_17935379	12.475	NM_001130009	GEN1	Gen endonuclease homolog 1 (Drosophila)
chrX_+_48542159	12.461	NM_000377	WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr14_+_75745480	12.396	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr6_-_32095993	12.389	NM_001136153 NM_004381	ATF6B	activating transcription factor 6 beta
chrX_+_67913490	12.323		STARD8	StAR-related lipid transfer (START) domain containing 8
chr2_+_143886898	12.290	NM_018460	ARHGAP15	Rho GTPase activating protein 15
chrX_+_67913479	12.286	NM_001142504	STARD8	StAR-related lipid transfer (START) domain containing 8
chr22_+_37678519	12.265		CYTH4	cytohesin 4
chr1_+_10003485	12.221	NM_022787	NMNAT1	nicotinamide nucleotide adenylyltransferase 1
chr15_+_75074417	12.141	NM_001127190 NM_004383	CSK	c-src tyrosine kinase
chr1_+_28995214	12.137	NM_006582 NM_024482	GMEB1	glucocorticoid modulatory element binding protein 1
chr19_-_5680910	12.132	NM_205767	C19orf70	chromosome 19 open reading frame 70
chr19_-_13213973	12.131	NM_005583	LYL1	lymphoblastic leukemia derived sequence 1
chr16_+_69166538	12.120		CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)
chr12_+_6898705	12.096		CD4	CD4 molecule
chr12_+_51318515	12.049	NM_014033	METTL7A	methyltransferase like 7A
chr5_+_156693051	12.042	NM_001037333 NM_001037332	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr6_-_170102098	11.921	NM_001202550 NM_182552	WDR27	WD repeat domain 27
chr1_+_158801105	11.888	NM_002432	MNDA	myeloid cell nuclear differentiation antigen
chr16_-_30366681	11.803	NM_006110	CD2BP2	CD2 (cytoplasmic tail) binding protein 2
chr16_+_28505920	11.797	NM_018690	APOBR	apolipoprotein B receptor
chr5_+_118604417	11.793	NM_001077654	TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr11_+_117857123	11.781		IL10RA	interleukin 10 receptor, alpha
chr11_+_65190272	11.772
chr12_-_51717941	11.735		BIN2	bridging integrator 2
chr22_-_21213099	11.721	NM_058004	PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr6_-_32497925	11.650	NM_002125	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr6_+_110012423	11.560	NM_014845	FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
chr12_+_112856701	11.490		PTPN11	protein tyrosine phosphatase, non-receptor type 11
chr2_+_143886969	11.477		ARHGAP15	Rho GTPase activating protein 15
chr22_+_22786283	11.472
chr1_+_26644380	11.374	NM_001803	CD52	CD52 molecule
chr19_+_58694444	11.372		ZNF274	zinc finger protein 274
chr6_-_32095974	11.354		ATF6B	activating transcription factor 6 beta
chr19_+_56186426	11.342	NM_001130072 NM_013333	EPN1	epsin 1
chr1_-_161519526	11.331		FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr15_-_64648359	11.325	NM_022048	CSNK1G1	casein kinase 1, gamma 1
chr12_-_92539614	11.235	NM_001731	BTG1	B-cell translocation gene 1, anti-proliferative

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.15	1.72e-21	GO:0009987	cellular process
1.22	1.20e-20	GO:0065007	biological regulation
1.74	2.92e-19	GO:0002376	immune system process
1.23	5.08e-17	GO:0050794	regulation of cellular process
1.21	1.13e-16	GO:0050789	regulation of biological process
1.52	1.56e-15	GO:0048583	regulation of response to stimulus
1.86	8.98e-15	GO:0006955	immune response
1.86	9.29e-14	GO:0002682	regulation of immune system process
1.34	5.93e-13	GO:0007165	signal transduction
1.30	1.55e-11	GO:0023052	signaling
1.27	8.94e-11	GO:0051716	cellular response to stimulus
1.96	4.24e-10	GO:0002684	positive regulation of immune system process
1.94	8.88e-10	GO:0050776	regulation of immune response
1.23	1.13e-09	GO:0043170	macromolecule metabolic process
1.36	1.41e-09	GO:0006950	response to stress
1.87	1.93e-09	GO:0001775	cell activation
1.66	3.99e-09	GO:0006952	defense response
1.18	1.46e-08	GO:0050896	response to stimulus
1.46	4.59e-08	GO:0009966	regulation of signal transduction
1.23	7.21e-08	GO:0044260	cellular macromolecule metabolic process
1.24	1.41e-07	GO:0019222	regulation of metabolic process
1.44	8.40e-07	GO:0035556	intracellular signal transduction
1.52	1.31e-06	GO:0032774	RNA biosynthetic process
1.24	1.63e-06	GO:0031323	regulation of cellular metabolic process
1.36	2.47e-06	GO:0006464	protein modification process
1.53	3.38e-06	GO:0009611	response to wounding
2.12	3.73e-06	GO:0051249	regulation of lymphocyte activation
1.28	3.91e-06	GO:0048518	positive regulation of biological process
2.03	6.38e-06	GO:0050865	regulation of cell activation
2.05	6.71e-06	GO:0002694	regulation of leukocyte activation
1.37	1.29e-05	GO:0023051	regulation of signaling
1.92	1.89e-05	GO:0050778	positive regulation of immune response
1.33	1.94e-05	GO:0043412	macromolecule modification
2.03	2.22e-05	GO:0030168	platelet activation
1.15	2.83e-05	GO:0044238	primary metabolic process
1.23	2.87e-05	GO:0080090	regulation of primary metabolic process
2.03	3.50e-05	GO:0002253	activation of immune response
1.50	4.26e-05	GO:0006351	transcription, DNA-dependent
1.33	5.78e-05	GO:0007166	cell surface receptor linked signaling pathway
1.67	6.10e-05	GO:0007596	blood coagulation
1.67	6.10e-05	GO:0050817	coagulation
1.26	6.12e-05	GO:0031326	regulation of cellular biosynthetic process
2.13	6.79e-05	GO:0002764	immune response-regulating signaling pathway
1.77	7.26e-05	GO:0051056	regulation of small GTPase mediated signal transduction
2.14	7.59e-05	GO:0002757	immune response-activating signal transduction
1.66	8.97e-05	GO:0007599	hemostasis
1.26	9.77e-05	GO:0009889	regulation of biosynthetic process
1.22	1.08e-04	GO:0016043	cellular component organization
1.22	1.34e-04	GO:0060255	regulation of macromolecule metabolic process
1.59	1.43e-04	GO:0042060	wound healing
1.47	1.50e-04	GO:0051704	multi-organism process
1.94	1.52e-04	GO:0045321	leukocyte activation
1.25	1.65e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.54	1.86e-04	GO:0050851	antigen receptor-mediated signaling pathway
1.13	1.93e-04	GO:0008152	metabolic process
1.23	2.95e-04	GO:0019538	protein metabolic process
2.10	3.22e-04	GO:0051251	positive regulation of lymphocyte activation
1.14	3.24e-04	GO:0044237	cellular metabolic process
1.48	3.48e-04	GO:0048584	positive regulation of response to stimulus
1.26	3.65e-04	GO:0010556	regulation of macromolecule biosynthetic process
2.04	4.21e-04	GO:0050867	positive regulation of cell activation
2.08	4.95e-04	GO:0050863	regulation of T cell activation
1.24	5.62e-04	GO:0051171	regulation of nitrogen compound metabolic process
2.38	5.69e-04	GO:0002768	immune response-regulating cell surface receptor signaling pathway
1.27	5.77e-04	GO:0006355	regulation of transcription, DNA-dependent
2.04	5.85e-04	GO:0002696	positive regulation of leukocyte activation
2.41	6.00e-04	GO:0002429	immune response-activating cell surface receptor signaling pathway
1.25	9.37e-04	GO:0044267	cellular protein metabolic process
1.25	1.14e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.20	1.38e-03	GO:0071840	cellular component organization or biogenesis
1.48	1.51e-03	GO:0006468	protein phosphorylation
1.29	1.64e-03	GO:0010467	gene expression
1.26	1.82e-03	GO:0051252	regulation of RNA metabolic process
1.55	1.99e-03	GO:0050878	regulation of body fluid levels
1.24	2.20e-03	GO:0048522	positive regulation of cellular process
2.12	3.38e-03	GO:0050870	positive regulation of T cell activation
1.56	3.40e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.39	3.73e-03	GO:0006793	phosphorus metabolic process
1.39	3.73e-03	GO:0006796	phosphate metabolic process
1.23	4.27e-03	GO:0010468	regulation of gene expression
1.45	5.79e-03	GO:0016192	vesicle-mediated transport
1.54	9.19e-03	GO:0080134	regulation of response to stress
1.28	9.39e-03	GO:0016070	RNA metabolic process
1.73	1.02e-02	GO:0006954	inflammatory response
1.57	1.39e-02	GO:0016044	cellular membrane organization
1.46	1.59e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.61	1.62e-02	GO:0007264	small GTPase mediated signal transduction
1.61	1.62e-02	GO:0010627	regulation of intracellular protein kinase cascade
1.56	1.72e-02	GO:0061024	membrane organization
1.62	1.80e-02	GO:0045087	innate immune response
1.86	1.80e-02	GO:0046649	lymphocyte activation
2.40	2.18e-02	GO:0007015	actin filament organization
1.40	2.35e-02	GO:0016310	phosphorylation
1.74	3.00e-02	GO:0030036	actin cytoskeleton organization
1.51	3.03e-02	GO:0009607	response to biotic stimulus
1.29	3.05e-02	GO:0065009	regulation of molecular function
1.39	3.98e-02	GO:0044093	positive regulation of molecular function
1.34	4.38e-02	GO:0042981	regulation of apoptosis
1.95	4.43e-02	GO:0002252	immune effector process
1.93	4.63e-02	GO:0002697	regulation of immune effector process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.08	8.29e-07	GO:0005622	intracellular
1.08	9.62e-07	GO:0044424	intracellular part
1.26	1.11e-04	GO:0044459	plasma membrane part
1.26	2.50e-04	GO:0005829	cytosol
1.59	5.30e-04	GO:0005768	endosome
3.11	3.26e-03	GO:0032587	ruffle membrane
1.12	4.15e-03	GO:0005634	nucleus
1.30	6.56e-03	GO:0005887	integral to plasma membrane
1.29	1.18e-02	GO:0031226	intrinsic to plasma membrane
2.43	1.24e-02	GO:0031256	leading edge membrane
1.03	1.57e-02	GO:0044464	cell part
1.03	1.63e-02	GO:0005623	cell
1.08	1.94e-02	GO:0005737	cytoplasm
1.08	2.13e-02	GO:0043227	membrane-bounded organelle
1.07	2.38e-02	GO:0043226	organelle
2.77	3.41e-02	GO:0030120	vesicle coat
1.07	3.83e-02	GO:0043229	intracellular organelle
1.07	4.09e-02	GO:0043231	intracellular membrane-bounded organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.20	1.96e-16	GO:0005515	protein binding
1.11	1.32e-14	GO:0005488	binding
3.55	2.53e-05	GO:0003823	antigen binding
1.60	4.10e-04	GO:0030695	GTPase regulator activity
1.59	4.77e-04	GO:0060589	nucleoside-triphosphatase regulator activity
2.00	1.35e-03	GO:0005085	guanyl-nucleotide exchange factor activity
2.23	3.63e-03	GO:0005057	receptor signaling protein activity
1.36	3.92e-03	GO:0001071	nucleic acid binding transcription factor activity
1.36	3.92e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
2.59	6.42e-03	GO:0035591	signaling adaptor activity
1.36	7.66e-03	GO:0030234	enzyme regulator activity
4.23	1.59e-02	GO:0019865	immunoglobulin binding
1.64	1.65e-02	GO:0005083	small GTPase regulator activity
1.20	3.47e-02	GO:0003677	DNA binding
1.49	4.10e-02	GO:0019904	protein domain specific binding
1.63	4.14e-02	GO:0032403	protein complex binding
1.37	4.63e-02	GO:0016773	phosphotransferase activity, alcohol group as acceptor