Motif ID: EVI1.p2

Z-value: 3.040


Transcription factors associated with EVI1.p2:

Gene SymbolEntrez IDGene Name
EVI1 2122 ecotropic viral integration site 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MECOMchr3_-_1693814170.581.2e-20Click!


Activity profile for motif EVI1.p2.

activity profile for motif EVI1.p2


Sorted Z-values histogram for motif EVI1.p2

Sorted Z-values for motif EVI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EVI1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_88450243 91.312 SPARCL1
SPARC-like 1 (hevin)
chr9_+_139871954 68.202 NM_000954
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr8_-_27115897 62.831 NM_030795
STMN4
stathmin-like 4
chr17_+_53344966 50.667 HLF
hepatic leukemia factor
chr2_-_224467095 49.880 SCG2
secretogranin II
chr12_-_15038724 48.480 NM_000900
NM_001190839
MGP

matrix Gla protein

chr6_-_31514620 43.243 NM_001204078
NM_130463
NM_138282
ATP6V1G2


ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2


chr8_-_27115935 41.642 STMN4
stathmin-like 4
chr10_+_106034886 39.622 NM_001191014
NM_001191015
GSTO2

glutathione S-transferase omega 2

chr14_-_76447445 39.253 TGFB3
transforming growth factor, beta 3
chr19_-_36643770 38.626 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr2_-_224467049 38.550 SCG2
secretogranin II
chr1_-_93399531 37.088


chr10_+_7745341 36.641 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr15_+_66874506 35.756


chr10_+_7745325 30.903 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr2_-_224467142 30.842 NM_003469
SCG2
secretogranin II
chr17_-_66951381 30.409 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr12_-_16758312 29.744 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_+_31515391 28.886 NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr8_-_27941387 28.637 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr2_-_89165652 28.571


chr2_-_145274916 28.421 ZEB2
zinc finger E-box binding homeobox 2
chr12_-_16757944 28.195 LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_+_80523376 27.948 STMN2
stathmin-like 2
chr5_+_140739589 27.204 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr6_-_22297729 27.162 NM_000948
PRL
prolactin
chr15_+_34261088 26.598 NM_012125
CHRM5
cholinergic receptor, muscarinic 5
chr12_+_20848288 26.107 NM_001145945
NM_001145946
NM_001145944
NM_017435
SLCO1C1



solute carrier organic anion transporter family, member 1C1



chr12_-_8218930 26.031 NM_004054
C3AR1
complement component 3a receptor 1
chr16_+_55542909 26.014 NM_017839
LPCAT2
lysophosphatidylcholine acyltransferase 2
chr12_-_8219001 25.900 C3AR1
complement component 3a receptor 1
chr10_+_7745284 25.774 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr11_+_92085261 25.523 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr10_-_88717319 25.318 NM_024756
MMRN2
multimerin 2
chr22_+_29138018 25.276 NM_172002
HSCB
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr6_-_116422408 25.274


chr6_+_31515352 25.269 NM_001144961
NM_005007
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr4_+_106631966 24.912 NM_001031720
GSTCD
glutathione S-transferase, C-terminal domain containing
chr8_-_110655418 24.319 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr2_+_189839132 23.777 COL3A1
collagen, type III, alpha 1
chr12_-_371994 23.356 NM_001190997
NM_001243392
NM_016615
SLC6A13


solute carrier family 6 (neurotransmitter transporter, GABA), member 13


chrX_+_101502093 23.222 NM_022053
NM_001099686
NXF2
NXF2B
nuclear RNA export factor 2
nuclear RNA export factor 2B
chr10_+_7745354 22.927 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr14_+_95047758 22.747 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chrX_+_103031753 22.695 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr12_-_9268440 22.571 A2M
alpha-2-macroglobulin
chr5_+_55147206 22.450 NM_001242637
NM_001242638
NM_139017
IL31RA


interleukin 31 receptor A


chr5_+_175511848 21.957 NM_001079529
FAM153B
family with sequence similarity 153, member B
chrX_-_101694848 21.956 NM_022053
NM_001099686
NXF2
NXF2B
nuclear RNA export factor 2
nuclear RNA export factor 2B
chr19_-_20844312 21.405 NM_001076675
NM_145297
ZNF626

zinc finger protein 626

chr22_-_31688329 21.379 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr4_-_176923572 21.304 NM_005277
NM_201592
GPM6A

glycoprotein M6A

chr6_+_126240369 20.961 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr1_-_182357871 20.703 GLUL
glutamate-ammonia ligase
chr6_+_52529157 20.691 LOC730101
uncharacterized LOC730101
chr3_-_145968819 20.525 PLSCR4
phospholipid scramblase 4
chr22_-_19512859 20.322 NM_001130861
NM_003277
CLDN5

claudin 5

chr3_-_145968958 20.277 NM_001128306
NM_001177304
NM_020353
PLSCR4


phospholipid scramblase 4


chr19_+_50031232 19.920 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr6_+_29624757 19.843 NM_001008228
NM_001008229
NM_001170418
NM_002433
NM_206809
NM_206810
NM_206811
NM_206812
NM_206814
MOG








myelin oligodendrocyte glycoprotein








chr14_+_95047792 19.703 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr2_+_26403584 19.473 NM_001191033
FAM59B
family with sequence similarity 59, member B
chr1_+_104292439 19.453 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr19_-_21950322 19.127 NM_173531
ZNF100
zinc finger protein 100
chr20_-_44455932 19.006 NM_003279
TNNC2
troponin C type 2 (fast)
chr1_+_209859524 18.894 NM_001206741
NM_181755
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr3_+_147127151 18.421 NM_003412
ZIC1
Zic family member 1
chr6_+_160327972 17.851 NM_002377
MAS1
MAS1 oncogene
chr9_-_107690435 17.835 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chrX_+_103031433 17.428 NM_001128834
PLP1
proteolipid protein 1
chr12_+_85430098 17.416 NM_001079910
LRRIQ1
leucine-rich repeats and IQ motif containing 1
chr18_-_53303129 17.212 NM_001243226
TCF4
transcription factor 4
chr13_+_46626949 17.178 LOC100509894
uncharacterized LOC100509894
chrX_+_103031797 17.075 PLP1
proteolipid protein 1
chr13_+_49280619 17.006 NM_020377
CYSLTR2
cysteinyl leukotriene receptor 2
chr2_+_169929009 16.973 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr7_-_8302141 16.744 NM_004968
ICA1
islet cell autoantigen 1, 69kDa
chrX_+_100805415 16.680 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr1_-_182357757 16.436 GLUL
glutamate-ammonia ligase
chr5_+_64920830 16.375 C5orf44
chromosome 5 open reading frame 44
chr2_+_166150340 16.124 NM_021007
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr9_+_40700290 16.016 NM_001083124
FAM75A3
family with sequence similarity 75, member A3
chr19_+_48964505 16.015 NM_170720
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr11_-_128894008 16.003 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr2_+_189839113 15.999 COL3A1
collagen, type III, alpha 1
chr4_-_76944585 15.982 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr22_+_36113917 15.852 NM_030642
APOL5
apolipoprotein L, 5
chr5_-_147162175 15.799 JAKMIP2
janus kinase and microtubule interacting protein 2
chr1_+_162602198 15.777 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr10_+_7745229 15.744 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr19_+_22235278 15.646 ZNF257
zinc finger protein 257
chr1_+_1385068 15.510 NM_001039211
ATAD3C
ATPase family, AAA domain containing 3C
chr9_-_95244750 15.461 NM_001193335
NM_017680
ASPN

asporin

chr19_-_52133589 15.412 NM_003830
SIGLEC5
sialic acid binding Ig-like lectin 5
chr2_+_189839078 15.284 NM_000090
COL3A1
collagen, type III, alpha 1
chrX_+_2959511 14.963 NM_001201539
ARSF
arylsulfatase F
chr20_-_48099178 14.886 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr1_+_152881022 14.847 NM_005547
IVL
involucrin
chr5_+_140588267 14.774 NM_018932
PCDHB12
protocadherin beta 12
chr5_-_64920100 14.749 TRIM23
tripartite motif containing 23
chr19_+_6135650 14.703 NM_030924
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr1_-_161279724 14.688 NM_000530
MPZ
myelin protein zero
chr6_+_123100645 14.660 NM_001446
FABP7
fatty acid binding protein 7, brain
chr6_-_88854989 14.656 NM_033181
CNR1
cannabinoid receptor 1 (brain)
chr12_-_9268513 14.417 A2M
alpha-2-macroglobulin
chr7_-_15601574 14.364 NM_001004320
AGMO
alkylglycerol monooxygenase
chr3_-_58200397 14.315 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr8_+_22857413 14.149 RHOBTB2
Rho-related BTB domain containing 2
chr4_+_62362838 14.055 NM_015236
LPHN3
latrophilin 3
chr19_+_19976625 14.055 NM_021047
ZNF253
zinc finger protein 253
chr9_+_82187469 14.023 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_-_46608039 14.022 NM_024512
LRRC2
leucine rich repeat containing 2
chr1_+_162332772 13.850 NM_001126060
NOS1AP
nitric oxide synthase 1 (neuronal) adaptor protein
chr1_-_149889362 13.752 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chrY_-_27198250 13.749 NM_001002760
NM_001002761
NM_004678
BPY2B
BPY2C
BPY2
basic charge, Y-linked, 2B
basic charge, Y-linked, 2C
basic charge, Y-linked, 2
chr19_+_50030874 13.740 NM_020650
RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr1_+_50569581 13.738 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_-_182922504 13.736 NM_030933
SHCBP1L
SHC SH2-domain binding protein 1-like
chr12_+_56732658 13.648 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr17_+_41857802 13.610 NM_001136483
C17orf105
chromosome 17 open reading frame 105
chrY_+_26764150 13.598 NM_001002760
NM_001002761
NM_004678
BPY2B
BPY2C
BPY2
basic charge, Y-linked, 2B
basic charge, Y-linked, 2C
basic charge, Y-linked, 2
chrY_+_25130409 13.598 NM_001002760
NM_001002761
NM_004678
BPY2B
BPY2C
BPY2
basic charge, Y-linked, 2B
basic charge, Y-linked, 2C
basic charge, Y-linked, 2
chr19_-_38720312 13.528 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr1_+_162602308 13.517 DDR2
discoidin domain receptor tyrosine kinase 2
chr5_-_147162251 13.503 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr19_+_22235253 13.497 NM_033468
ZNF257
zinc finger protein 257
chr1_-_150587879 13.418


chr5_+_64920557 13.394 NM_001093755
NM_001093756
NM_001243737
NM_024941
C5orf44



chromosome 5 open reading frame 44



chr5_+_161112657 13.378 NM_000811
GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6
chr12_-_10251520 13.347 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chrX_+_15525430 13.305 NM_001721
BMX
BMX non-receptor tyrosine kinase
chrX_-_43741593 13.277 NM_000898
MAOB
monoamine oxidase B
chr1_-_13390747 13.246 NM_001012276
PRAMEF8
PRAMEF7
PRAME family member 8
PRAME family member 7
chr14_+_95078713 13.228 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chrX_-_49965657 13.213 NM_003886
AKAP4
A kinase (PRKA) anchor protein 4
chr12_-_91576805 13.089 NM_001920
DCN
decorin
chr11_-_108368918 13.084 NM_153705
KDELC2
KDEL (Lys-Asp-Glu-Leu) containing 2
chr7_+_47694841 12.985 NM_001123065
C7orf65
chromosome 7 open reading frame 65
chr6_-_22303014 12.959 NM_001163558
PRL
prolactin
chr12_-_10151689 12.937 NM_001099431
NM_016509
CLEC1B

C-type lectin domain family 1, member B

chr4_+_55095263 12.823 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chrX_+_91090459 12.794 NM_001168360
NM_001168361
NM_001168362
NM_001168363
PCDH11X



protocadherin 11 X-linked



chr1_+_12976449 12.747 NM_001012276
PRAMEF8
PRAMEF7
PRAME family member 8
PRAME family member 7
chr14_-_94844881 12.619 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_146697155 12.614 NM_001144829
NM_001144830
NM_001461
FMO5


flavin containing monooxygenase 5


chr4_-_10041833 12.608 NM_001001290
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr12_+_72079873 12.535 NM_018279
TMEM19
transmembrane protein 19
chrX_-_65835845 12.488 NM_001242310
EDA2R
ectodysplasin A2 receptor
chr5_+_140165875 12.342 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chrX_-_78623006 12.332 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr1_+_170904611 12.316 NM_001163629
NM_025063
C1orf129

chromosome 1 open reading frame 129

chr3_+_133495925 12.206 TF
transferrin
chr7_+_142829169 12.084 NM_002652
PIP
prolactin-induced protein
chr21_-_39956823 12.083 NM_001243429
ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr9_+_82186846 12.069 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr8_-_6837568 12.043 NM_004084
NM_001042500
DEFA1
DEFA1B
defensin, alpha 1
defensin, alpha 1B
chr5_-_151066492 11.974 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chrX_-_62975005 11.970 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr6_+_153019029 11.948 NM_025107
MYCT1
myc target 1
chr4_-_176923480 11.902 GPM6A
glycoprotein M6A
chr14_-_81687265 11.867 NM_015859
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr1_-_168513201 11.840 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr8_-_6875777 11.685 NM_004084
NM_005217
NM_001042500
DEFA1
DEFA3
DEFA1B
defensin, alpha 1
defensin, alpha 3, neutrophil-specific
defensin, alpha 1B
chr16_-_21289571 11.682 CRYM
crystallin, mu
chr9_-_43630729 11.649 NM_001145196
FAM75A6
family with sequence similarity 75, member A6
chr1_+_104198301 11.591 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr9_+_134378335 11.518 POMT1
protein-O-mannosyltransferase 1
chr5_-_137475076 11.506 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr8_-_38008332 11.492 NM_000349
STAR
steroidogenic acute regulatory protein
chr7_+_86273219 11.468 NM_000840
GRM3
glutamate receptor, metabotropic 3
chr12_-_9268475 11.465 A2M
alpha-2-macroglobulin
chr3_+_186330711 11.446 AHSG
alpha-2-HS-glycoprotein
chr5_-_41213513 11.435 NM_000065
C6
complement component 6
chrX_+_155227245 11.429 NM_002186
IL9R
interleukin 9 receptor
chr20_+_57875481 11.317 NM_000114
NM_207032
NM_207033
NM_207034
EDN3



endothelin 3



chr3_-_187454247 11.316 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr22_-_27014037 11.300 CRYBB1
crystallin, beta B1
chr1_+_205236591 11.194 TMCC2
transmembrane and coiled-coil domain family 2
chr8_+_133879202 11.171 NM_003235
TG
thyroglobulin
chr8_-_17767871 11.135


chr18_-_44561967 11.088 NM_016427
TCEB3B
transcription elongation factor B polypeptide 3B (elongin A2)
chr16_+_7382750 11.088 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr5_-_75919051 11.047 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr5_-_64920149 11.028 NM_001656
NM_033227
NM_033228
TRIM23


tripartite motif containing 23


chr22_+_23213671 10.998 IGLV4-3
immunoglobulin lambda variable 4-3
chr21_-_42557165 10.983 NM_182832
PLAC4
placenta-specific 4
chr3_+_44916097 10.918 NM_003241
TGM4
transglutaminase 4 (prostate)
chr18_+_61582744 10.891 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr10_+_57358749 10.791 NM_001190478
MTRNR2L5
MT-RNR2-like 5
chr5_-_132161863 10.759 NM_133456
SHROOM1
shroom family member 1
chr19_-_51587466 10.677 NM_022046
KLK14
kallikrein-related peptidase 14
chr18_-_67624159 10.672 NM_006566
CD226
CD226 molecule
chrX_+_135730335 10.658 NM_000074
CD40LG
CD40 ligand
chrY_+_59330251 10.650 NM_002186
IL9R
interleukin 9 receptor
chr5_-_146460991 10.649 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr1_+_15802595 10.637 NM_015849
CELA2B
chymotrypsin-like elastase family, member 2B
chr16_-_21289637 10.578 CRYM
crystallin, mu
chr14_-_50862616 10.566 NM_004196
CDKL1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr5_+_156820161 10.514 CYFIP2
cytoplasmic FMR1 interacting protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 4.84e-09 GO:0032501 multicellular organismal process
2.06 1.63e-08 GO:0009611 response to wounding
1.43 4.11e-08 GO:0023052 signaling
2.53 7.42e-08 GO:0050776 regulation of immune response
2.18 8.96e-08 GO:0002682 regulation of immune system process
2.51 1.47e-07 GO:0002684 positive regulation of immune system process
1.66 2.14e-07 GO:0007166 cell surface receptor linked signaling pathway
2.03 4.76e-07 GO:0006952 defense response
1.42 2.12e-06 GO:0007165 signal transduction
3.25 3.16e-06 GO:0050867 positive regulation of cell activation
2.90 3.25e-06 GO:0050865 regulation of cell activation
2.94 3.66e-06 GO:0002694 regulation of leukocyte activation
1.96 6.68e-06 GO:0048584 positive regulation of response to stimulus
3.21 8.03e-06 GO:0002696 positive regulation of leukocyte activation
2.72 9.10e-06 GO:0006954 inflammatory response
2.67 1.59e-05 GO:0050778 positive regulation of immune response
1.73 1.68e-05 GO:0002376 immune system process
1.43 3.50e-05 GO:0048731 system development
1.24 6.67e-05 GO:0050896 response to stimulus
1.91 1.02e-04 GO:0007155 cell adhesion
1.91 1.02e-04 GO:0022610 biological adhesion
1.43 5.51e-04 GO:0006950 response to stress
1.30 6.49e-04 GO:0051716 cellular response to stimulus
1.84 8.12e-04 GO:0006955 immune response
1.33 9.43e-04 GO:0007275 multicellular organismal development
1.18 9.50e-04 GO:0065007 biological regulation
2.91 1.09e-03 GO:0051251 positive regulation of lymphocyte activation
2.64 1.37e-03 GO:0051249 regulation of lymphocyte activation
1.98 1.46e-03 GO:0007186 G-protein coupled receptor protein signaling pathway
3.00 1.54e-03 GO:0002697 regulation of immune effector process
1.35 1.66e-03 GO:0048856 anatomical structure development
4.99 2.21e-03 GO:0032649 regulation of interferon-gamma production
1.59 2.43e-03 GO:0051239 regulation of multicellular organismal process
2.57 2.58e-03 GO:0002253 activation of immune response
2.77 2.86e-03 GO:0003012 muscle system process
2.02 3.12e-03 GO:0009628 response to abiotic stimulus
1.42 3.70e-03 GO:0065008 regulation of biological quality
4.41 4.31e-03 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
1.78 4.37e-03 GO:0007267 cell-cell signaling
2.76 4.68e-03 GO:0050863 regulation of T cell activation
4.34 5.42e-03 GO:0002819 regulation of adaptive immune response
2.79 6.06e-03 GO:0006936 muscle contraction
2.28 6.73e-03 GO:0016337 cell-cell adhesion
1.29 6.84e-03 GO:0032502 developmental process
3.77 7.79e-03 GO:0002699 positive regulation of immune effector process
8.82 9.95e-03 GO:0046640 regulation of alpha-beta T cell proliferation
1.44 1.12e-02 GO:0048583 regulation of response to stimulus
2.84 1.14e-02 GO:0042445 hormone metabolic process
2.90 1.29e-02 GO:0050870 positive regulation of T cell activation
2.55 1.46e-02 GO:0010817 regulation of hormone levels
1.65 2.35e-02 GO:0006811 ion transport
5.88 2.39e-02 GO:0032729 positive regulation of interferon-gamma production
9.63 2.66e-02 GO:0045026 plasma membrane fusion
3.53 3.60e-02 GO:0034754 cellular hormone metabolic process
7.27 4.86e-02 GO:0032660 regulation of interleukin-17 production

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.79 7.59e-16 GO:0044459 plasma membrane part
2.00 1.42e-12 GO:0005887 integral to plasma membrane
1.73 1.85e-12 GO:0005576 extracellular region
1.46 2.02e-12 GO:0005886 plasma membrane
1.96 6.08e-12 GO:0031226 intrinsic to plasma membrane
1.44 8.78e-12 GO:0071944 cell periphery
2.13 1.18e-09 GO:0005615 extracellular space
1.93 5.90e-09 GO:0044421 extracellular region part
1.21 1.17e-06 GO:0016020 membrane
1.23 6.10e-06 GO:0044425 membrane part
1.24 6.03e-05 GO:0031224 intrinsic to membrane
1.24 9.17e-05 GO:0016021 integral to membrane
1.98 5.86e-03 GO:0009986 cell surface
1.50 2.00e-02 GO:0000267 cell fraction
1.68 3.24e-02 GO:0030054 cell junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.90 1.17e-03 GO:0004866 endopeptidase inhibitor activity
2.79 2.43e-03 GO:0061135 endopeptidase regulator activity
2.75 3.07e-03 GO:0030414 peptidase inhibitor activity
1.77 3.29e-03 GO:0005509 calcium ion binding
3.45 3.37e-03 GO:0004867 serine-type endopeptidase inhibitor activity
3.11 4.89e-03 GO:0019955 cytokine binding
2.46 7.11e-03 GO:0005125 cytokine activity
1.38 7.62e-03 GO:0004871 signal transducer activity
1.38 7.62e-03 GO:0060089 molecular transducer activity
1.51 1.24e-02 GO:0005215 transporter activity
2.45 1.53e-02 GO:0005126 cytokine receptor binding
1.55 1.85e-02 GO:0022892 substrate-specific transporter activity
1.57 1.96e-02 GO:0022857 transmembrane transporter activity
2.40 2.22e-02 GO:0061134 peptidase regulator activity
1.40 2.66e-02 GO:0004872 receptor activity