Motif ID: FOSL2.p2

Z-value: 2.506


Transcription factors associated with FOSL2.p2:

Gene SymbolEntrez IDGene Name
FOSL2 2355 FOS-like antigen 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOSL2chr2_+_286163600.341.8e-07Click!


Activity profile for motif FOSL2.p2.

activity profile for motif FOSL2.p2


Sorted Z-values histogram for motif FOSL2.p2

Sorted Z-values for motif FOSL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOSL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_22758538 91.407


chr22_+_22735134 90.076 CYAT1
immunoglobulin lambda light chain-like
chr22_+_23040394 83.849 IGL@
immunoglobulin lambda locus
chr2_-_89292396 72.515 IGKC
immunoglobulin kappa constant
chr22_+_22569155 65.977


chr2_-_89442551 65.191 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr22_+_22735207 60.774 IGLJ3
immunoglobulin lambda joining 3
chr2_-_89513056 55.308 IGKC
immunoglobulin kappa constant
chr7_+_30960914 52.900 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr7_+_23286386 52.672 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286277 52.654 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr7_+_23286384 51.291 GPNMB
glycoprotein (transmembrane) nmb
chr22_+_22723972 50.903


chr7_+_23286390 50.776 GPNMB
glycoprotein (transmembrane) nmb
chr6_+_33043702 50.695 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr22_+_23165273 48.614


chr2_-_89619820 45.614 IGKC
immunoglobulin kappa constant
chr7_+_23286420 40.370 GPNMB
glycoprotein (transmembrane) nmb
chr12_-_15114495 37.832 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr22_+_22735202 34.929


chr22_+_22712091 32.477 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr5_+_150020201 29.972 NM_001109974
NM_007286
SYNPO

synaptopodin

chr22_+_23229959 29.738 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr22_+_21986968 29.187 NM_152612
CCDC116
coiled-coil domain containing 116
chr3_-_121379757 28.489 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_121379701 27.939 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr7_+_94024201 27.931 COL1A2
collagen, type I, alpha 2
chr22_+_23213671 26.932 IGLV4-3
immunoglobulin lambda variable 4-3
chr7_+_94023872 26.625 NM_000089
COL1A2
collagen, type I, alpha 2
chr5_-_140012730 26.336 CD14
CD14 molecule
chr14_-_107179043 26.212 IGHA1
immunoglobulin heavy constant alpha 1
chr5_-_149535420 25.718 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr12_-_91573264 25.038 NM_133503
DCN
decorin
chr22_+_23063107 24.070 IGLJ3
immunoglobulin lambda joining 3
chr20_-_44455932 24.057 NM_003279
TNNC2
troponin C type 2 (fast)
chr14_-_94855120 22.959 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr19_-_11688441 22.647 ACP5
acid phosphatase 5, tartrate resistant
chr14_-_94854910 22.554 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr22_+_23029175 22.292 IGLV3-25
immunoglobulin lambda variable 3-25
chr22_+_22676814 22.180


chr22_+_23010757 21.441


chr2_+_90077732 21.363


chr22_+_23154240 21.186


chr10_-_73611041 20.891 PSAP
prosaposin
chr5_-_149492934 20.787 NM_005211
CSF1R
colony stimulating factor 1 receptor
chr10_-_73611005 20.601 PSAP
prosaposin
chr19_-_11688484 20.344 ACP5
acid phosphatase 5, tartrate resistant
chr4_-_71532341 20.225 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr5_-_140013034 19.831 NM_000591
CD14
CD14 molecule
chr2_-_216259197 19.746 FN1
fibronectin 1
chr8_-_82395401 19.136 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr17_-_38721701 19.096 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr12_-_10282680 18.846 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr14_-_94849552 18.716 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr5_-_149466173 18.540 CSF1R
colony stimulating factor 1 receptor
chr10_-_73611050 18.342 NM_001042465
NM_001042466
NM_002778
PSAP


prosaposin


chr16_+_31366519 18.228 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr10_-_73610958 17.945 PSAP
prosaposin
chr10_+_17270257 17.916 NM_003380
VIM
vimentin
chr8_-_27472188 17.850 CLU
clusterin
chr5_-_149466126 17.576 CSF1R
colony stimulating factor 1 receptor
chr16_+_31366468 17.573 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr11_-_2162340 17.466 NM_001127598
IGF2
insulin-like growth factor 2 (somatomedin A)
chr16_+_31366529 17.288 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr20_+_44637539 17.185 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr19_-_56348127 16.582 NM_145007
NLRP11
NLR family, pyrin domain containing 11
chr5_-_134914968 16.501 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chrX_-_106960268 16.363 NM_004089
TSC22D3
TSC22 domain family, member 3
chr19_-_11688508 16.336 NM_001611
ACP5
acid phosphatase 5, tartrate resistant
chr2_+_90211704 15.980


chr14_-_24777184 15.963 CIDEB
cell death-inducing DFFA-like effector b
chr4_-_71532206 15.790 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr6_-_134496833 15.676 SGK1
serum/glucocorticoid regulated kinase 1
chr5_-_141061798 15.635 NM_022481
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr18_-_74207145 15.574 NM_014643
ZNF516
zinc finger protein 516
chr5_-_149466094 15.399 CSF1R
colony stimulating factor 1 receptor
chr10_-_95360959 15.324 NM_006744
RBP4
retinol binding protein 4, plasma
chr16_-_1280162 15.180 NM_024164
TPSB2
TPSAB1
tryptase beta 2 (gene/pseudogene)
tryptase alpha/beta 1
chr14_-_24777160 14.989 CIDEB
cell death-inducing DFFA-like effector b
chr14_-_24777153 14.979 CIDEB
cell death-inducing DFFA-like effector b
chr16_+_2083264 14.885 NM_001252073
NM_001252075
NM_001252076
SLC9A3R2


solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2


chr1_+_152974222 14.720 NM_001097589
NM_005416
SPRR3

small proline-rich protein 3

chr5_-_141061749 14.452 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr4_+_6695565 14.325 NM_005980
S100P
S100 calcium binding protein P
chr2_+_89185055 14.198


chr17_+_7482804 14.166 NM_001251
NM_001040059
CD68

CD68 molecule

chr5_-_140013285 14.156 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr8_-_27472298 14.144 NM_001831
CLU
clusterin
chr19_-_51587466 13.914 NM_022046
KLK14
kallikrein-related peptidase 14
chr1_+_209929378 13.778 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr10_+_17270469 13.673 VIM
vimentin
chr2_-_145274916 13.256 ZEB2
zinc finger E-box binding homeobox 2
chr17_+_7482938 13.208 CD68
CD68 molecule
chr2_+_169926084 13.137 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_+_152956563 13.020 NM_001199828
NM_005987
SPRR1A

small proline-rich protein 1A

chr2_+_113875469 12.994 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr12_-_8219001 12.651 C3AR1
complement component 3a receptor 1
chr3_-_58200397 12.584 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr1_+_27719151 12.228 NM_005281
GPR3
G protein-coupled receptor 3
chr3_-_187454247 12.195 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr12_-_8218930 12.178 NM_004054
C3AR1
complement component 3a receptor 1
chr14_-_64970319 11.922 NM_006977
ZBTB25
zinc finger and BTB domain containing 25
chr19_-_52255099 11.909 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr5_-_138533982 11.849 SIL1
SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae)
chr1_-_203155867 11.701 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_203155910 11.423 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr19_+_51628136 11.349 NM_001198558
NM_014441
SIGLEC9

sialic acid binding Ig-like lectin 9

chr19_+_859658 11.347 NM_001928
CFD
complement factor D (adipsin)
chr3_-_114343791 11.213 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr22_-_50968137 11.187 NM_001113756
TYMP
thymidine phosphorylase
chr17_+_7482980 11.186 CD68
CD68 molecule
chr1_-_203155827 11.135 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr7_+_142495142 11.125


chr6_+_36410800 11.082 KCTD20
potassium channel tetramerisation domain containing 20
chr16_+_1306272 11.001 NM_012217
TPSD1
tryptase delta 1
chr14_+_69726868 10.965 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr22_+_23134980 10.927


chr19_+_859673 10.730 CFD
complement factor D (adipsin)
chr12_-_8043743 10.554 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr12_-_7656285 10.520 NM_004244
NM_203416
CD163

CD163 molecule

chr5_-_138533998 10.501 SIL1
SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae)
chr12_-_48152860 10.417 NM_001098531
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr1_+_150480584 10.387 ECM1
extracellular matrix protein 1
chr2_-_152830448 10.295 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr5_+_35856990 10.292 NM_002185
IL7R
interleukin 7 receptor
chr6_+_138188352 10.246 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_-_153348057 10.220 NM_005621
S100A12
S100 calcium binding protein A12
chr12_-_10021932 10.216 CLEC2B
C-type lectin domain family 2, member B
chr6_-_24877453 10.118 NM_015864
FAM65B
family with sequence similarity 65, member B
chr19_+_41903718 10.112 BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr7_+_150264457 10.011 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr20_-_44539542 9.993 PLTP
phospholipid transfer protein
chr19_+_50432399 9.933 NM_001193646
ATF5
activating transcription factor 5
chr16_-_1832576 9.871 NM_080861
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr7_-_98467615 9.747 TMEM130
transmembrane protein 130
chr19_+_50016606 9.668 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr3_+_183903970 9.482 ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr5_-_138534026 9.425 NM_001037633
NM_022464
SIL1

SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae)

chr4_-_39033981 9.372 NM_024943
TMEM156
transmembrane protein 156
chr19_-_51537996 9.311 NM_019598
NM_145894
NM_145895
KLK12


kallikrein-related peptidase 12


chr11_+_60739114 9.260 NM_006725
CD6
CD6 molecule
chr1_-_11866079 9.256 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr14_-_24777064 9.243


chr12_+_10365415 9.179 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr1_+_17634689 9.163 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr17_-_34207308 9.011 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr1_-_182357871 8.983 GLUL
glutamate-ammonia ligase
chr19_-_49140569 8.934 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr1_+_154377847 8.917 IL6R
interleukin 6 receptor
chr6_+_36410543 8.907 NM_173562
KCTD20
potassium channel tetramerisation domain containing 20
chr12_+_21679190 8.882 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr16_-_1832571 8.876 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr9_+_4985082 8.862 JAK2
Janus kinase 2
chr3_-_69171536 8.853 NM_198271
LMOD3
leiomodin 3 (fetal)
chr8_+_22210311 8.834 PIWIL2
piwi-like 2 (Drosophila)
chr12_-_48152180 8.775 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr12_+_52445185 8.700 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr22_+_22764094 8.658


chr3_+_183903862 8.608 NM_018358
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chrX_-_154563735 8.594 NM_001289
CLIC2
chloride intracellular channel 2
chr16_+_56965747 8.549 NM_001010989
NM_001010990
NM_014685
HERPUD1


homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1


chr6_+_106546736 8.531 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr6_+_50786438 8.506 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr1_-_57045214 8.495 PPAP2B
phosphatidic acid phosphatase type 2B
chr16_+_56966025 8.466 HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr12_+_103981050 8.461 NM_017564
STAB2
stabilin 2
chr1_-_160232269 8.455 DCAF8
DDB1 and CUL4 associated factor 8
chr1_-_120311466 8.383 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr16_+_28996369 8.354 NM_001014987
NM_001014988
NM_014387
LAT


linker for activation of T cells


chr22_+_37309618 8.351 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_-_203155745 8.340 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr4_+_154178525 8.329 TRIM2
tripartite motif containing 2
chr15_+_41136622 8.210 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr3_-_194090459 8.168 NM_001135057
NM_130830
LRRC15

leucine rich repeat containing 15

chr2_-_64371444 8.127 NM_020651
PELI1
pellino homolog 1 (Drosophila)
chr9_+_132251323 8.090 LOC100506190
uncharacterized LOC100506190
chr2_-_85895863 8.050 NM_000542
NM_198843
SFTPB

surfactant protein B

chr8_+_11561710 8.043 NM_002052
GATA4
GATA binding protein 4
chr15_+_89182038 8.015 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr16_+_30968614 7.991 NM_014712
SETD1A
SET domain containing 1A
chr1_+_150122415 7.968 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr19_-_19738973 7.899 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr1_+_150480486 7.858 NM_001202858
NM_004425
NM_022664
ECM1


extracellular matrix protein 1


chr2_+_68961912 7.849 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr1_+_150122246 7.846 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr6_+_154407641 7.829 NM_001145287
OPRM1
opioid receptor, mu 1
chr9_+_132251403 7.791 LOC100506190
uncharacterized LOC100506190
chr19_+_21264952 7.779 NM_182515
ZNF714
zinc finger protein 714
chr12_+_7060433 7.752 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr17_+_42264582 7.705 TMUB2
transmembrane and ubiquitin-like domain containing 2
chr3_+_148447966 7.699 NM_032049
AGTR1
angiotensin II receptor, type 1
chr15_+_40331417 7.666 LOC100131089
uncharacterized LOC100131089
chr1_+_154378044 7.632 IL6R
interleukin 6 receptor
chr11_-_120008801 7.606 TRIM29
tripartite motif containing 29
chr3_+_58223228 7.573 NM_020676
ABHD6
abhydrolase domain containing 6
chr16_+_28505920 7.535 NM_018690
APOBR
apolipoprotein B receptor
chr11_+_60197061 7.527 NM_023945
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr21_+_43619798 7.506 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr11_-_2162167 7.497 IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_-_44233499 7.492 NM_004556
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.06 6.08e-15 GO:0002376 immune system process
1.73 1.37e-11 GO:0048583 regulation of response to stimulus
2.20 1.77e-10 GO:0006955 immune response
2.13 1.93e-08 GO:0002682 regulation of immune system process
2.01 6.39e-08 GO:0048584 positive regulation of response to stimulus
1.28 8.78e-08 GO:0050896 response to stimulus
1.22 1.14e-07 GO:0065007 biological regulation
1.53 3.26e-07 GO:0042221 response to chemical stimulus
2.26 5.24e-07 GO:0001775 cell activation
3.63 6.02e-07 GO:0032496 response to lipopolysaccharide
1.73 7.26e-07 GO:0051239 regulation of multicellular organismal process
1.45 8.81e-07 GO:0048731 system development
1.72 1.10e-06 GO:0010033 response to organic substance
1.46 1.31e-06 GO:0048518 positive regulation of biological process
3.40 1.80e-06 GO:0002237 response to molecule of bacterial origin
1.60 3.67e-06 GO:0023051 regulation of signaling
1.40 6.02e-06 GO:0048856 anatomical structure development
2.11 6.04e-06 GO:0006928 cellular component movement
2.24 6.64e-06 GO:0050776 regulation of immune response
1.64 7.62e-06 GO:0009966 regulation of signal transduction
1.21 1.02e-05 GO:0050789 regulation of biological process
1.34 2.34e-05 GO:0023052 signaling
2.19 2.96e-05 GO:0002684 positive regulation of immune system process
1.36 3.14e-05 GO:0007165 signal transduction
1.52 3.28e-05 GO:0048513 organ development
1.48 3.47e-05 GO:0065008 regulation of biological quality
1.76 3.74e-05 GO:0042127 regulation of cell proliferation
2.07 8.42e-05 GO:0009607 response to biotic stimulus
1.51 9.02e-05 GO:0007166 cell surface receptor linked signaling pathway
1.80 1.31e-04 GO:0006952 defense response
2.53 1.36e-04 GO:0009617 response to bacterium
2.02 1.54e-04 GO:0010647 positive regulation of cell communication
2.50 1.93e-04 GO:0030334 regulation of cell migration
2.01 1.95e-04 GO:0023056 positive regulation of signaling
1.68 2.16e-04 GO:0010646 regulation of cell communication
1.30 2.38e-04 GO:0051716 cellular response to stimulus
2.47 2.73e-04 GO:2000145 regulation of cell motility
2.49 3.17e-04 GO:0050865 regulation of cell activation
2.02 3.28e-04 GO:0009967 positive regulation of signal transduction
1.41 3.42e-04 GO:0006950 response to stress
1.33 3.81e-04 GO:0007275 multicellular organismal development
1.73 3.82e-04 GO:0009611 response to wounding
2.07 4.64e-04 GO:0051094 positive regulation of developmental process
2.11 5.02e-04 GO:0051707 response to other organism
1.19 5.15e-04 GO:0050794 regulation of cellular process
1.71 5.66e-04 GO:0050793 regulation of developmental process
1.68 5.99e-04 GO:0009605 response to external stimulus
2.92 6.89e-04 GO:0030335 positive regulation of cell migration
2.92 6.89e-04 GO:2000147 positive regulation of cell motility
2.45 9.53e-04 GO:0002694 regulation of leukocyte activation
2.11 1.16e-03 GO:0010627 regulation of intracellular protein kinase cascade
2.07 1.30e-03 GO:0016477 cell migration
1.29 1.38e-03 GO:0032502 developmental process
2.82 1.43e-03 GO:0040017 positive regulation of locomotion
1.11 1.64e-03 GO:0009987 cellular process
1.38 1.91e-03 GO:0048522 positive regulation of cellular process
1.99 2.18e-03 GO:0048870 cell motility
1.99 2.18e-03 GO:0051674 localization of cell
1.23 2.34e-03 GO:0032501 multicellular organismal process
2.15 2.53e-03 GO:0051240 positive regulation of multicellular organismal process
2.73 2.85e-03 GO:0051272 positive regulation of cellular component movement
2.26 3.04e-03 GO:0040012 regulation of locomotion
1.74 3.09e-03 GO:2000026 regulation of multicellular organismal development
2.40 3.16e-03 GO:0030168 platelet activation
2.25 3.35e-03 GO:0051270 regulation of cellular component movement
8.06 4.13e-03 GO:0030513 positive regulation of BMP signaling pathway
4.12 4.92e-03 GO:0060326 cell chemotaxis
2.26 5.28e-03 GO:0010740 positive regulation of intracellular protein kinase cascade
2.41 6.05e-03 GO:0051249 regulation of lymphocyte activation
1.64 6.72e-03 GO:0051704 multi-organism process
1.60 1.22e-02 GO:0032879 regulation of localization
2.20 1.36e-02 GO:0048534 hemopoietic or lymphoid organ development
1.64 1.38e-02 GO:0040011 locomotion
4.27 1.55e-02 GO:0032680 regulation of tumor necrosis factor production
3.42 1.65e-02 GO:0002576 platelet degranulation
2.26 1.76e-02 GO:0030097 hemopoiesis
2.06 1.77e-02 GO:0045597 positive regulation of cell differentiation
3.24 2.07e-02 GO:0050730 regulation of peptidyl-tyrosine phosphorylation
2.12 2.51e-02 GO:0050778 positive regulation of immune response
1.61 2.61e-02 GO:0009888 tissue development
2.49 2.70e-02 GO:0051251 positive regulation of lymphocyte activation
2.10 3.25e-02 GO:0002520 immune system development
3.54 3.75e-02 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
2.12 4.02e-02 GO:0001817 regulation of cytokine production
1.36 4.89e-02 GO:0030154 cell differentiation
2.36 4.99e-02 GO:0050867 positive regulation of cell activation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.94 1.66e-10 GO:0044421 extracellular region part
2.01 5.62e-09 GO:0005615 extracellular space
1.50 2.40e-07 GO:0044459 plasma membrane part
1.51 5.64e-07 GO:0005576 extracellular region
1.59 4.75e-05 GO:0031226 intrinsic to plasma membrane
1.28 4.96e-05 GO:0005886 plasma membrane
1.59 5.27e-05 GO:0005887 integral to plasma membrane
1.27 1.05e-04 GO:0071944 cell periphery
2.57 1.23e-04 GO:0030141 stored secretory granule
2.09 1.99e-04 GO:0031012 extracellular matrix
2.12 8.33e-04 GO:0005578 proteinaceous extracellular matrix
2.81 5.23e-03 GO:0044420 extracellular matrix part
2.48 2.42e-02 GO:0043235 receptor complex
3.63 2.79e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
3.49 4.20e-02 GO:0031983 vesicle lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.44 9.06e-08 GO:0030246 carbohydrate binding
2.78 1.88e-05 GO:0005529 sugar binding
3.04 3.84e-05 GO:0004252 serine-type endopeptidase activity
1.18 9.11e-05 GO:0005515 protein binding
1.10 9.35e-05 GO:0005488 binding
2.71 3.17e-04 GO:0008236 serine-type peptidase activity
2.67 4.70e-04 GO:0017171 serine hydrolase activity
1.60 9.65e-04 GO:0005102 receptor binding
2.94 4.47e-03 GO:0019955 cytokine binding
2.43 4.68e-03 GO:0005126 cytokine receptor binding
2.14 6.03e-03 GO:0032403 protein complex binding
1.92 1.32e-02 GO:0004175 endopeptidase activity
1.53 1.42e-02 GO:0001071 nucleic acid binding transcription factor activity
1.53 1.42e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
2.38 2.97e-02 GO:0001871 pattern binding
2.38 2.97e-02 GO:0030247 polysaccharide binding
2.68 4.48e-02 GO:0019838 growth factor binding