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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: FOXD3.p2

Z-value: 2.515

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_+_123234462	98.392		STAG2	stromal antigen 2
chr5_+_159436143	91.677		TTC1	tetratricopeptide repeat domain 1
chr11_-_16996559	86.757		RPL36A	ribosomal protein L36a
chr11_-_67450536	80.088		RPL37	ribosomal protein L37
chr12_+_27175482	61.870	NM_004264	MED21	mediator complex subunit 21
chr6_+_74171610	60.147		MTO1	mitochondrial translation optimization 1 homolog (S. cerevisiae)
chr2_+_216176808	59.672		ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr7_-_87849341	58.258		SRI	sorcin
chr4_+_146031528	56.972		ABCE1	ATP-binding cassette, sub-family E (OABP), member 1
chr2_-_47134945	56.556		MCFD2	multiple coagulation factor deficiency 2
chr14_+_102276125	53.752	NM_002719 NM_178586 NM_178587	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr3_+_172472246	52.583	NM_018098	ECT2	epithelial cell transforming sequence 2 oncogene
chr2_+_216176678	52.046	NM_004044	ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr5_+_159436155	49.728	NM_003314	TTC1	tetratricopeptide repeat domain 1
chr2_+_216176818	49.619		ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr6_-_150057659	49.419		NUP43	nucleoporin 43kDa
chr22_-_43036606	47.743	NM_001165877	ATP5L2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr3_-_25683825	47.395		TOP2B	topoisomerase (DNA) II beta 180kDa
chr16_+_30064410	46.386	NM_000034	ALDOA	aldolase A, fructose-bisphosphate
chr20_+_19870209	45.230	NM_018993	RIN2	Ras and Rab interactor 2
chr14_+_67831484	44.787		EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr1_-_108786663	44.300	NM_001143989	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chr16_+_30064470	43.790		ALDOA	aldolase A, fructose-bisphosphate
chr7_+_6617035	43.781	NM_001134387 NM_001134388 NM_001134389 NM_018106	ZDHHC4	zinc finger, DHHC-type containing 4
chr2_+_109204904	43.150	NM_001193488	LIMS1	LIM and senescent cell antigen-like domains 1
chrX_+_118714297	42.686	NM_181777	UBE2A	ubiquitin-conjugating enzyme E2A
chr1_+_40735749	42.664		ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr4_-_83347222	42.075		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr9_+_75766777	40.190	NM_000700	ANXA1	annexin A1
chr11_-_17191287	40.082	NM_002645	PIK3C2A	phosphoinositide-3-kinase, class 2, alpha polypeptide
chr12_-_102512277	39.273	NM_024057	NUP37	nucleoporin 37kDa
chr13_-_37679800	38.788	NM_145203	CSNK1A1L	casein kinase 1, alpha 1-like
chr15_-_66648991	38.485	NM_017858	TIPIN	TIMELESS interacting protein
chr20_+_19915716	37.646		RIN2	Ras and Rab interactor 2
chr8_+_132991171	37.608		EFR3A	EFR3 homolog A (S. cerevisiae)
chr2_+_109204745	37.532	NM_004987	LIMS1	LIM and senescent cell antigen-like domains 1
chr15_-_72501017	37.106		PKM2	pyruvate kinase, muscle
chr5_+_132406080	36.971		HSPA4	heat shock 70kDa protein 4
chr9_+_75766794	36.245		ANXA1	annexin A1
chr6_+_74171453	35.548	NM_001123226 NM_012123 NM_133645	MTO1	mitochondrial translation optimization 1 homolog (S. cerevisiae)
chr2_+_109204777	35.501		LIMS1	LIM and senescent cell antigen-like domains 1
chr12_-_46633551	34.577		SLC38A1	solute carrier family 38, member 1
chrX_-_102942968	34.559	NM_001142419 NM_001142420 NM_001142421 NM_001142422 NM_001142427 NM_001142428 NM_001142431 NM_001142432	MORF4L2	mortality factor 4 like 2
chrX_-_129272014	34.074	NM_001130846	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr6_-_38670829	34.018		GLO1	glyoxalase I
chr2_-_85637486	33.674	NM_001747	CAPG	capping protein (actin filament), gelsolin-like
chr19_+_13134782	33.405		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr6_-_38670882	32.874		GLO1	glyoxalase I
chr10_-_931694	31.658	NM_015155	LARP4B	La ribonucleoprotein domain family, member 4B
chr14_+_102276279	31.477		PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr12_+_64803741	31.330		XPOT	exportin, tRNA (nuclear export receptor for tRNAs)
chr2_-_20527120	31.172	NM_015317	PUM2	pumilio homolog 2 (Drosophila)
chr6_-_75965845	30.814		TMEM30A	transmembrane protein 30A
chr16_-_28437663	30.795	NM_001199142	EIF3C	eukaryotic translation initiation factor 3, subunit C
chr11_+_18415917	30.692	NM_001135239 NM_001165415 NM_001165416 NM_005566	LDHA	lactate dehydrogenase A
chr20_+_48552928	29.731		RNF114	ring finger protein 114
chr20_+_48552902	29.539	NM_018683	RNF114	ring finger protein 114
chr20_-_5107185	29.050	NM_002592	PCNA	proliferating cell nuclear antigen
chr16_+_28699878	28.988	NM_001199142	EIF3C	eukaryotic translation initiation factor 3, subunit C
chr14_-_75600111	28.800		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr14_+_56078735	28.679		KTN1	kinectin 1 (kinesin receptor)
chr21_-_27512668	28.613	NM_001136016	APP	amyloid beta (A4) precursor protein
chr11_-_88070901	28.204		CTSC	cathepsin C
chr12_+_32832209	28.013		DNM1L	dynamin 1-like
chr12_+_32832128	27.993	NM_005690 NM_012062 NM_012063	DNM1L	dynamin 1-like
chr1_-_150669499	27.947	NM_018178	GOLPH3L	golgi phosphoprotein 3-like
chr1_+_74701070	27.641	NM_015978	TNNI3K	TNNI3 interacting kinase
chr5_+_34687663	27.108	NM_001145523	RAI14	retinoic acid induced 14
chr1_-_77685076	26.959	NM_005482	PIGK	phosphatidylinositol glycan anchor biosynthesis, class K
chr15_+_80390757	26.844	NM_001242919	ZFAND6	zinc finger, AN1-type domain 6
chr12_+_32832272	26.682		DNM1L	dynamin 1-like
chr11_-_88070840	26.608		CTSC	cathepsin C
chr6_-_38670904	26.581		GLO1	glyoxalase I
chr19_+_11200037	26.519	NM_000527 NM_001195798 NM_001195799 NM_001195800 NM_001195802 NM_001195803	LDLR	low density lipoprotein receptor
chr5_+_132432880	26.403		HSPA4	heat shock 70kDa protein 4
chr3_-_149086884	26.236		TM4SF1	transmembrane 4 L six family member 1
chr12_+_13043955	26.123	NM_003979	GPRC5A	G protein-coupled receptor, family C, group 5, member A
chr6_-_38670871	25.963		GLO1	glyoxalase I
chr18_+_33234532	25.903	NM_020474	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr16_-_47005339	25.599		DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr10_-_98336445	25.565		TM9SF3	transmembrane 9 superfamily member 3
chr10_+_112344076	25.386		SMC3	structural maintenance of chromosomes 3
chr11_+_125495030	25.336	NM_001114121 NM_001114122 NM_001244846	CHEK1	checkpoint kinase 1
chr8_+_66582107	25.183	NM_001145838	MTFR1	mitochondrial fission regulator 1
chr5_+_147795459	25.048		FBXO38	F-box protein 38
chr12_+_27175501	24.935		MED21	mediator complex subunit 21
chr6_-_42185599	24.785		MRPS10	mitochondrial ribosomal protein S10
chr1_+_24018268	24.669	NM_000975 NM_001199802	RPL11	ribosomal protein L11
chr3_+_9476506	24.563
chr19_+_10362598	24.369	NM_015956 NM_146387 NM_146388	MRPL4	mitochondrial ribosomal protein L4
chr6_-_38670915	24.327		GLO1	glyoxalase I
chr13_-_41593405	24.086		ELF1	E74-like factor 1 (ets domain transcription factor)
chr13_+_52598678	23.873	NM_021645	ALG11 UTP14C	asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr20_+_48552935	23.758		RNF114	ring finger protein 114
chr13_+_53035227	23.677		CKAP2	cytoskeleton associated protein 2
chr13_-_41593491	23.573	NM_172373	ELF1	E74-like factor 1 (ets domain transcription factor)
chr5_-_111091947	23.538	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr6_-_42185586	23.438		MRPS10	mitochondrial ribosomal protein S10
chr17_+_65714038	23.096	NM_015462	NOL11	nucleolar protein 11
chr10_-_98325100	23.095		TM9SF3	transmembrane 9 superfamily member 3
chr6_+_64356430	23.045	NM_015153	PHF3	PHD finger protein 3
chr17_+_26646120	22.974	NM_014573	TMEM97	transmembrane protein 97
chr7_-_96339074	22.670		SHFM1	split hand/foot malformation (ectrodactyly) type 1
chr2_-_86948244	22.493	NM_001198954	RNF103-CHMP3	RNF103-CHMP3 readthrough
chr10_-_27057776	22.437		ABI1	abl-interactor 1
chr8_-_80993009	22.379	NM_001025252	TPD52	tumor protein D52
chr11_-_88070905	22.105	NM_001114173 NM_001814 NM_148170	CTSC	cathepsin C
chr9_+_79968344	22.082		VPS13A	vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr21_+_30400229	21.751		USP16	ubiquitin specific peptidase 16
chr5_+_96212167	21.649		ERAP2	endoplasmic reticulum aminopeptidase 2
chr6_-_159240367	21.647		EZR	ezrin
chr4_-_84035888	21.596		PLAC8	placenta-specific 8
chr2_-_225370687	21.575		CUL3	cullin 3
chr3_+_142375738	21.256	NM_001172312	PLS1	plastin 1
chr15_-_55562483	20.958	NM_183234 NM_004580	RAB27A	RAB27A, member RAS oncogene family
chr9_-_130700762	20.853	NM_003863	DPM2	dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr1_+_24018293	20.654		RPL11	ribosomal protein L11
chrX_+_70765479	20.630		OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr6_-_159240433	20.630	NM_001111077	EZR	ezrin
chr11_-_64578765	20.576	NM_130803 NM_130804	MEN1	multiple endocrine neoplasia I
chr6_-_38670922	20.566	NM_006708	GLO1	glyoxalase I
chr9_+_110047049	20.480	NM_001244713	RAD23B	RAD23 homolog B (S. cerevisiae)
chr9_-_88715024	20.462	NM_177937	GOLM1	golgi membrane protein 1
chr1_-_154578775	20.287	NM_001193495	ADAR	adenosine deaminase, RNA-specific
chr3_+_133502876	20.116	NM_021203	SRPRB	signal recognition particle receptor, B subunit
chr3_-_105421044	20.084		CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr2_+_109384601	20.056		RANBP2	RAN binding protein 2
chr2_-_151344145	20.053	NM_005168	RND3	Rho family GTPase 3
chr2_-_170430312	20.048	NM_024622	FASTKD1	FAST kinase domains 1
chr17_-_42144986	20.019	NM_152344	LSM12	LSM12 homolog (S. cerevisiae)
chr15_+_80364902	19.870	NM_001242915 NM_001242916	ZFAND6	zinc finger, AN1-type domain 6
chr8_-_30585442	19.849	NM_000637 NM_001195102 NM_001195103 NM_001195104	GSR	glutathione reductase
chr1_+_46016454	19.800	NM_001202413 NM_001202414 NM_006066 NM_153326	AKR1A1	aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr10_-_126849010	19.766		CTBP2	C-terminal binding protein 2
chr5_+_70944968	19.764		MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr9_+_118916069	19.678	NM_002581	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr7_+_28475233	19.677	NM_004904	CREB5	cAMP responsive element binding protein 5
chr15_+_64680002	19.436	NM_016213	TRIP4	thyroid hormone receptor interactor 4
chr12_+_2904289	19.304		FKBP4	FK506 binding protein 4, 59kDa
chr4_-_84035908	19.274	NM_001130715 NM_016619	PLAC8	placenta-specific 8
chrX_+_119737905	19.144		MCTS1	malignant T cell amplified sequence 1
chr5_+_159848835	19.016	NM_004219	PTTG1	pituitary tumor-transforming 1
chr3_+_172468469	19.011		ECT2	epithelial cell transforming sequence 2 oncogene
chr20_-_31989303	19.006		CDK5RAP1	CDK5 regulatory subunit associated protein 1
chr6_-_42185603	19.003	NM_018141	MRPS10	mitochondrial ribosomal protein S10
chr2_+_172821874	18.768		HAT1	histone acetyltransferase 1
chr2_+_201170603	18.357	NM_015535	SPATS2L	spermatogenesis associated, serine-rich 2-like
chr15_+_57511616	18.302	NM_207040	TCF12	transcription factor 12
chr4_+_41614725	18.288		LIMCH1	LIM and calponin homology domains 1
chr7_+_77469446	18.241	NM_001127357 NM_001127359 NM_020432	PHTF2	putative homeodomain transcription factor 2
chr4_-_139163222	18.229	NM_014331	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr15_-_60690115	18.188	NM_001002857 NM_001002858 NM_001136015 NM_004039	ANXA2	annexin A2
chr6_-_159240398	18.160		EZR	ezrin
chr11_+_87032428	18.055		TMEM135	transmembrane protein 135
chr1_+_44064509	17.969		PTPRF	protein tyrosine phosphatase, receptor type, F
chr14_+_39649711	17.955		PNN	pinin, desmosome associated protein
chrX_-_23855456	17.860		RPL9	ribosomal protein L9
chr17_-_48945338	17.818	NM_001243877	TOB1	transducer of ERBB2, 1
chr18_-_47814691	17.725	NM_001101654 NM_014593	CXXC1	CXXC finger protein 1
chr15_-_42749710	17.351	NM_022473	ZFP106	zinc finger protein 106 homolog (mouse)
chr14_+_67656109	17.330	NM_173526	FAM71D	family with sequence similarity 71, member D
chr6_-_31830551	17.062		NEU1	sialidase 1 (lysosomal sialidase)
chr2_+_201170795	17.038	NM_001100422 NM_001100424 NM_001100423	SPATS2L	spermatogenesis associated, serine-rich 2-like
chr12_+_56915587	16.849	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chr3_+_130569368	16.666	NM_001199180 NM_001199181 NM_001199182	ATP2C1	ATPase, Ca++ transporting, type 2C, member 1
chr4_-_76878558	16.385		SDAD1	SDA1 domain containing 1
chr17_-_7578810	16.325	NM_001126115 NM_001126116 NM_001126117	TP53	tumor protein p53
chr20_-_31989330	16.208	NM_016082 NM_016408	CDK5RAP1	CDK5 regulatory subunit associated protein 1
chr22_-_43355886	16.171	NM_001184971	PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr19_+_1026271	16.143	NM_004368 NM_201277	CNN2	calponin 2
chr11_+_69467210	16.142		CCND1	cyclin D1
chr16_-_23607603	16.023	NM_005003	NDUFAB1	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr7_+_28725597	16.020	NM_001011666	CREB5	cAMP responsive element binding protein 5
chr18_+_9102618	15.976	NM_021074	NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr1_-_161147757	15.905	NM_001199873 NM_001199874 NM_003779	B4GALT3	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr17_-_30228715	15.769	NM_018428	UTP6	UTP6, small subunit (SSU) processome component, homolog (yeast)
chr9_+_127962850	15.684	NM_005833	RABEPK	Rab9 effector protein with kelch motifs
chr5_-_68665839	15.638	NM_001015891 NM_001015892	TAF9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr2_-_152146373	15.632	NM_004688	NMI	N-myc (and STAT) interactor
chr6_-_159240399	15.574		EZR	ezrin
chr8_-_6420454	15.546	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr3_-_189838673	15.503		LEPREL1	leprecan-like 1
chr19_-_39826676	15.332	NM_004877	GMFG	glia maturation factor, gamma
chr3_-_15839674	15.298	NM_001195098	ANKRD28	ankyrin repeat domain 28
chr6_-_127664511	15.275		ECHDC1	enoyl CoA hydratase domain containing 1
chr2_-_74382352	15.265
chrX_+_119737743	15.258	NM_014060	MCTS1	malignant T cell amplified sequence 1
chr2_+_183582667	15.210		DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10
chr6_-_144416633	15.095		SF3B5	splicing factor 3b, subunit 5, 10kDa
chr12_-_80307690	15.093	NM_001143886	PPP1R12A	protein phosphatase 1, regulatory subunit 12A
chr2_-_10952855	15.093	NM_005742	PDIA6	protein disulfide isomerase family A, member 6
chr2_-_100046262	15.045		REV1	REV1 homolog (S. cerevisiae)
chr4_-_170679027	14.999	NM_017867	C4orf27	chromosome 4 open reading frame 27
chr11_+_57529233	14.941	NM_001085458 NM_001085459 NM_001085460 NM_001085461 NM_001085462 NM_001085463 NM_001085464 NM_001085465 NM_001085466 NM_001085467 NM_001085468 NM_001085469 NM_001206883 NM_001206884 NM_001206885 NM_001206886 NM_001206887 NM_001206888 NM_001206889 NM_001206890 NM_001206891 NM_001331	CTNND1	catenin (cadherin-associated protein), delta 1
chr19_-_10613767	14.896	NM_203500	KEAP1	kelch-like ECH-associated protein 1
chr9_-_14086901	14.880		NFIB	nuclear factor I/B
chr10_-_58121011	14.876		ZWINT	ZW10 interactor
chr15_-_25650647	14.843	NM_130838	UBE3A	ubiquitin protein ligase E3A
chr14_-_55658205	14.791	NM_001146015 NM_014750	DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr13_-_37573474	14.756	NM_001142364 NM_013338	ALG5	asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog (S. cerevisiae)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.40	6.28e-29	GO:0044237	cellular metabolic process
1.35	1.26e-26	GO:0008152	metabolic process
1.49	1.09e-24	GO:0044260	cellular macromolecule metabolic process
1.45	2.22e-24	GO:0043170	macromolecule metabolic process
1.36	6.00e-24	GO:0044238	primary metabolic process
1.19	2.08e-22	GO:0009987	cellular process
1.52	4.10e-18	GO:0006807	nitrogen compound metabolic process
1.58	8.58e-18	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.52	3.15e-17	GO:0034641	cellular nitrogen compound metabolic process
1.63	4.79e-16	GO:0090304	nucleic acid metabolic process
1.61	7.42e-11	GO:0016070	RNA metabolic process
1.58	1.17e-10	GO:0010467	gene expression
1.61	1.73e-10	GO:0009059	macromolecule biosynthetic process
1.61	3.05e-10	GO:0034645	cellular macromolecule biosynthetic process
1.47	3.14e-09	GO:0048519	negative regulation of biological process
1.43	2.47e-08	GO:0044267	cellular protein metabolic process
1.46	9.21e-08	GO:0048523	negative regulation of cellular process
1.37	1.04e-07	GO:0019538	protein metabolic process
1.42	1.41e-07	GO:0044249	cellular biosynthetic process
1.41	2.69e-07	GO:0009058	biosynthetic process
1.33	4.31e-07	GO:0071840	cellular component organization or biogenesis
3.01	5.04e-07	GO:0000082	G1/S transition of mitotic cell cycle
1.38	7.82e-07	GO:0071841	cellular component organization or biogenesis at cellular level
1.86	1.12e-06	GO:0006396	RNA processing
1.65	3.28e-06	GO:0007049	cell cycle
1.92	5.01e-06	GO:0016071	mRNA metabolic process
1.31	6.61e-06	GO:0016043	cellular component organization
1.86	1.00e-05	GO:0000278	mitotic cell cycle
1.35	2.33e-05	GO:0071842	cellular component organization at cellular level
1.80	2.41e-05	GO:0051726	regulation of cell cycle
1.80	2.63e-05	GO:0009057	macromolecule catabolic process
2.10	2.86e-05	GO:0010564	regulation of cell cycle process
2.42	3.00e-05	GO:0000075	cell cycle checkpoint
2.18	3.39e-05	GO:0051329	interphase of mitotic cell cycle
2.14	6.54e-05	GO:0051325	interphase
1.85	6.78e-05	GO:0044265	cellular macromolecule catabolic process
1.66	9.56e-05	GO:0022402	cell cycle process
1.85	9.69e-05	GO:0006974	response to DNA damage stimulus
2.33	1.05e-04	GO:0071156	regulation of cell cycle arrest
1.71	1.53e-04	GO:0022403	cell cycle phase
1.63	2.42e-04	GO:0033554	cellular response to stress
1.16	3.01e-04	GO:0050794	regulation of cellular process
1.31	3.98e-04	GO:0048518	positive regulation of biological process
1.15	4.03e-04	GO:0050789	regulation of biological process
1.51	4.97e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.14	6.30e-04	GO:0065007	biological regulation
1.92	6.52e-04	GO:0006397	mRNA processing
1.72	8.84e-04	GO:0006259	DNA metabolic process
1.49	9.90e-04	GO:0044248	cellular catabolic process
1.32	1.27e-03	GO:0048522	positive regulation of cellular process
1.43	1.39e-03	GO:0009056	catabolic process
2.29	1.39e-03	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.29	1.39e-03	GO:0000398	nuclear mRNA splicing, via spliceosome
1.53	1.70e-03	GO:0032774	RNA biosynthetic process
2.01	1.81e-03	GO:0008380	RNA splicing
2.60	2.22e-03	GO:0007093	mitotic cell cycle checkpoint
1.45	2.73e-03	GO:0009893	positive regulation of metabolic process
1.95	2.80e-03	GO:0043632	modification-dependent macromolecule catabolic process
2.23	2.84e-03	GO:0000375	RNA splicing, via transesterification reactions
1.25	3.16e-03	GO:0060255	regulation of macromolecule metabolic process
1.30	3.52e-03	GO:0006950	response to stress
1.48	3.62e-03	GO:0051246	regulation of protein metabolic process
2.04	3.73e-03	GO:0007346	regulation of mitotic cell cycle
1.44	4.14e-03	GO:0051641	cellular localization
2.18	4.91e-03	GO:0071843	cellular component biogenesis at cellular level
1.66	4.95e-03	GO:0051276	chromosome organization
1.95	5.81e-03	GO:0006412	translation
1.85	8.40e-03	GO:0030163	protein catabolic process
2.64	9.07e-03	GO:0000077	DNA damage checkpoint
1.37	9.32e-03	GO:0006996	organelle organization
1.89	1.12e-02	GO:0019941	modification-dependent protein catabolic process
1.78	1.15e-02	GO:0016032	viral reproduction
1.88	1.15e-02	GO:0051603	proteolysis involved in cellular protein catabolic process
1.97	1.23e-02	GO:0015980	energy derivation by oxidation of organic compounds
2.59	1.31e-02	GO:0000084	S phase of mitotic cell cycle
1.45	1.33e-02	GO:0051649	establishment of localization in cell
1.70	1.61e-02	GO:0034621	cellular macromolecular complex subunit organization
2.54	1.88e-02	GO:0051320	S phase
1.84	2.06e-02	GO:0044257	cellular protein catabolic process
1.42	2.07e-02	GO:0044085	cellular component biogenesis
2.13	2.22e-02	GO:0022613	ribonucleoprotein complex biogenesis
1.52	2.76e-02	GO:0046907	intracellular transport
1.42	2.79e-02	GO:0031325	positive regulation of cellular metabolic process
1.86	2.89e-02	GO:0006511	ubiquitin-dependent protein catabolic process
2.47	3.17e-02	GO:0031570	DNA integrity checkpoint
1.45	3.24e-02	GO:0032268	regulation of cellular protein metabolic process
1.31	3.25e-02	GO:0043412	macromolecule modification
1.83	3.27e-02	GO:0043434	response to peptide hormone stimulus
1.71	3.37e-02	GO:0044262	cellular carbohydrate metabolic process
1.74	4.65e-02	GO:0006091	generation of precursor metabolites and energy

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.19	5.02e-27	GO:0044424	intracellular part
1.18	6.90e-26	GO:0005622	intracellular
1.25	8.06e-24	GO:0043227	membrane-bounded organelle
1.25	8.93e-24	GO:0043231	intracellular membrane-bounded organelle
1.26	1.23e-21	GO:0005737	cytoplasm
1.37	7.64e-21	GO:0044446	intracellular organelle part
1.21	1.30e-20	GO:0043229	intracellular organelle
1.21	1.65e-20	GO:0043226	organelle
1.36	3.06e-20	GO:0044422	organelle part
1.48	1.75e-18	GO:0032991	macromolecular complex
1.64	1.46e-17	GO:0044428	nuclear part
1.59	3.48e-16	GO:0031974	membrane-enclosed lumen
1.58	1.25e-15	GO:0043233	organelle lumen
1.57	9.29e-15	GO:0070013	intracellular organelle lumen
1.64	1.76e-14	GO:0031981	nuclear lumen
1.31	1.87e-14	GO:0005634	nucleus
1.27	1.33e-12	GO:0044444	cytoplasmic part
1.70	1.16e-11	GO:0005654	nucleoplasm
1.40	5.25e-10	GO:0043234	protein complex
2.04	5.68e-09	GO:0030529	ribonucleoprotein complex
1.44	8.47e-08	GO:0005829	cytosol
1.73	3.10e-06	GO:0044451	nucleoplasm part
1.04	5.25e-04	GO:0044464	cell part
1.04	5.43e-04	GO:0005623	cell
2.49	6.45e-04	GO:0005681	spliceosomal complex
1.27	6.60e-04	GO:0043228	non-membrane-bounded organelle
1.27	6.60e-04	GO:0043232	intracellular non-membrane-bounded organelle
1.29	5.46e-03	GO:0031090	organelle membrane
1.64	6.46e-03	GO:0005730	nucleolus
1.64	1.47e-02	GO:0044427	chromosomal part
1.56	2.62e-02	GO:0005694	chromosome
10.74	3.43e-02	GO:0070552	BRISC complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.35	3.36e-31	GO:0005515	protein binding
1.14	7.12e-17	GO:0005488	binding
1.75	1.05e-07	GO:0003723	RNA binding
4.07	1.96e-03	GO:0043130	ubiquitin binding
3.86	4.05e-03	GO:0032182	small conjugating protein binding
1.21	2.01e-02	GO:0003676	nucleic acid binding
2.19	2.16e-02	GO:0003735	structural constituent of ribosome
2.06	3.29e-02	GO:0016758	transferase activity, transferring hexosyl groups
1.14	3.70e-02	GO:0003824	catalytic activity