Motif ID: FOXN1.p2

Z-value: 1.996


Transcription factors associated with FOXN1.p2:

Gene SymbolEntrez IDGene Name
FOXN1 8456 forkhead box N1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXN1chr17_+_26850958-0.622.6e-24Click!


Activity profile for motif FOXN1.p2.

activity profile for motif FOXN1.p2


Sorted Z-values histogram for motif FOXN1.p2

Sorted Z-values for motif FOXN1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXN1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_8938745 28.961 ENO1
enolase 1, (alpha)
chr1_-_8938727 26.185 ENO1
enolase 1, (alpha)
chr1_-_8939150 26.005 NM_001428
ENO1
enolase 1, (alpha)
chr14_+_52456322 23.692 C14orf166
chromosome 14 open reading frame 166
chr19_-_42806928 21.767 NM_001145939
NM_001145940
PAFAH1B3

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

chr4_-_174255454 20.957 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr1_-_8938691 20.468 ENO1
enolase 1, (alpha)
chrX_-_153775427 20.380 G6PD
glucose-6-phosphate dehydrogenase
chr2_-_61764661 19.848 XPO1
exportin 1 (CRM1 homolog, yeast)
chr2_+_113403433 19.297 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr2_+_187351032 19.117 ZC3H15
zinc finger CCCH-type containing 15
chr15_-_23034307 19.105 NIPA2
non imprinted in Prader-Willi/Angelman syndrome 2
chr1_+_44440595 18.947 NM_001039457
NM_004047
ATP6V0B

ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b

chr18_+_29672568 18.813 NM_001191324
NM_198128
RNF138

ring finger protein 138

chr1_+_44440623 18.561 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr12_+_104609501 18.545 NM_001093771
TXNRD1
thioredoxin reductase 1
chr19_-_41859519 18.435 TGFB1
transforming growth factor, beta 1
chr4_-_1713914 17.842 NM_006527
SLBP
stem-loop binding protein
chr4_-_103748254 17.767 NM_181892
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr14_+_52456192 17.684 NM_016039
C14orf166
chromosome 14 open reading frame 166
chr14_+_54863672 17.605 NM_001130851
NM_005192
CDKN3

cyclin-dependent kinase inhibitor 3

chr15_-_90777144 17.546 CIB1
calcium and integrin binding 1 (calmyrin)
chr2_+_187350992 17.374 ZC3H15
zinc finger CCCH-type containing 15
chr20_-_49547451 17.104 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chrX_-_153775064 16.879 NM_000402
G6PD
glucose-6-phosphate dehydrogenase
chr1_-_197115566 16.853 NM_001206846
NM_018136
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr12_+_120933911 16.335 DYNLL1
dynein, light chain, LC8-type 1
chr11_+_4116059 16.326 RRM1
ribonucleotide reductase M1
chr9_-_130889993 16.291 PTGES2
prostaglandin E synthase 2
chr10_+_94352809 16.104 NM_004523
KIF11
kinesin family member 11
chr2_+_187350870 15.986 NM_018471
ZC3H15
zinc finger CCCH-type containing 15
chrX_+_40440229 15.930 ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chrX_+_40440145 15.918 NM_005765
ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr1_-_28241233 15.762 NM_002946
RPA2
replication protein A2, 32kDa
chr4_-_100871482 15.718 NM_002106
H2AFZ
H2A histone family, member Z
chr12_+_120933832 15.465 NM_001037495
NM_003746
DYNLL1

dynein, light chain, LC8-type 1

chr12_+_70637493 15.236 NM_001199303
CNOT2
CCR4-NOT transcription complex, subunit 2
chr1_+_44440673 14.934 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr3_-_67705000 14.918 NM_001177599
NM_003848
SUCLG2

succinate-CoA ligase, GDP-forming, beta subunit

chr20_-_48729664 14.689 NM_001032288
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chrX_+_40440261 14.626 ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr17_+_79670495 14.602 MRPL12
mitochondrial ribosomal protein L12
chr19_-_41859830 14.533 NM_000660
TGFB1
transforming growth factor, beta 1
chr9_-_116172951 14.437 NM_017443
POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr4_-_100871431 14.278 H2AFZ
H2A histone family, member Z
chr1_-_115300586 14.179 CSDE1
cold shock domain containing E1, RNA-binding
chr8_-_17104103 14.148 CNOT7
CCR4-NOT transcription complex, subunit 7
chr9_+_33025270 14.115 DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr9_+_33025302 14.086 DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr11_+_4115923 13.971 NM_001033
RRM1
ribonucleotide reductase M1
chrX_-_16887974 13.902 NM_001198719
RBBP7
retinoblastoma binding protein 7
chr12_+_104680712 13.847 NM_003330
NM_182729
NM_182742
NM_182743
TXNRD1



thioredoxin reductase 1



chr15_-_83736105 13.808 NM_001011885
NM_025238
BTBD1

BTB (POZ) domain containing 1

chr8_+_26149080 13.727 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr9_+_114393543 13.702 NM_001015882
NM_004125
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr5_+_65440004 13.556 NM_001077199
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr2_-_61765345 13.434 XPO1
exportin 1 (CRM1 homolog, yeast)
chr17_-_62777621 13.394 LOC146880
Rho GTPase activating protein 27 pseudogene
chr1_-_115300561 13.348 CSDE1
cold shock domain containing E1, RNA-binding
chr9_+_33025207 13.074 NM_001539
DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr1_-_245027210 12.873 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr17_+_79670396 12.852 NM_002949
MRPL12
mitochondrial ribosomal protein L12
chr1_-_40562909 12.807 PPT1
palmitoyl-protein thioesterase 1
chr1_-_40562917 12.775 PPT1
palmitoyl-protein thioesterase 1
chr5_+_149340287 12.726 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr16_+_81040515 12.714 CENPN
centromere protein N
chr19_-_41859332 12.681 TGFB1
transforming growth factor, beta 1
chr1_-_241683060 12.555 NM_000143
FH
fumarate hydratase
chr16_-_57481270 12.494 NM_020313
CIAPIN1
cytokine induced apoptosis inhibitor 1
chr9_-_132597561 12.309 NM_016520
C9orf78
chromosome 9 open reading frame 78
chr18_+_9914202 12.153 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr20_+_35807695 12.126 RPN2
ribophorin II
chr7_-_105162551 12.123 NM_019042
PUS7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr8_-_101962767 12.087 NM_001135702
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr16_+_71929432 11.966 NM_014761
IST1
increased sodium tolerance 1 homolog (yeast)
chr20_+_55043682 11.868 C20orf43
chromosome 20 open reading frame 43
chr17_-_48474678 11.862 LRRC59
leucine rich repeat containing 59
chr6_-_18264638 11.820 NM_001134709
NM_003472
DEK

DEK oncogene

chr3_-_150263899 11.662 SERP1
stress-associated endoplasmic reticulum protein 1
chr14_-_23058062 11.631 DAD1
defender against cell death 1
chr9_-_116172635 11.621 POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr5_+_149340437 11.620 SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr9_-_116172658 11.578 POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr5_+_179248089 11.512 SQSTM1
sequestosome 1
chr3_-_186524226 11.487 NM_002916
RFC4
replication factor C (activator 1) 4, 37kDa
chr20_+_35807747 11.447 RPN2
ribophorin II
chr1_-_241683011 11.350 FH
fumarate hydratase
chr12_-_6960406 11.343 NM_031299
CDCA3
cell division cycle associated 3
chr6_+_52930217 11.257 FBXO9
F-box protein 9
chr17_-_56065596 11.150 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr11_+_4116077 11.129 RRM1
ribonucleotide reductase M1
chr14_+_24605393 11.108 PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr15_+_66161769 11.060 NM_001206836
NM_004663
RAB11A

RAB11A, member RAS oncogene family

chr4_+_110354825 10.961 SEC24B
SEC24 family, member B (S. cerevisiae)
chr3_-_189838673 10.923 LEPREL1
leprecan-like 1
chr17_-_46178559 10.810 NM_006807
CBX1
chromobox homolog 1
chr12_+_131356557 10.705 NM_006325
RAN
RAN, member RAS oncogene family
chr2_+_28113598 10.704 BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr9_-_130889965 10.646 PTGES2
prostaglandin E synthase 2
chr4_+_57302448 10.589 PAICS
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr17_-_76921076 10.553 TIMP2
TIMP metallopeptidase inhibitor 2
chr17_+_7155821 10.553 C17orf81
chromosome 17 open reading frame 81
chr19_+_14544216 10.504 PKN1
protein kinase N1
chr21_-_40555308 10.389 PSMG1
proteasome (prosome, macropain) assembly chaperone 1
chr12_+_120933916 10.374 DYNLL1
dynein, light chain, LC8-type 1
chr16_-_66864864 10.349 NM_001018159
NM_001018160
NM_003905
NAE1


NEDD8 activating enzyme E1 subunit 1


chr2_+_130939500 10.344 NM_025029
MZT2B
mitotic spindle organizing protein 2B
chr11_+_32605337 10.344 EIF3M
eukaryotic translation initiation factor 3, subunit M
chr22_+_20105076 10.331 RANBP1
RAN binding protein 1
chr4_+_110354927 10.320 NM_001042734
NM_006323
SEC24B

SEC24 family, member B (S. cerevisiae)

chr9_-_116172572 10.318 POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr19_-_41859253 10.286 TGFB1
transforming growth factor, beta 1
chr1_-_235490801 10.182 NM_001206794
ARID4B
AT rich interactive domain 4B (RBP1-like)
chr2_-_61765367 10.170 XPO1
exportin 1 (CRM1 homolog, yeast)
chr1_-_25256767 10.127 NM_004350
RUNX3
runt-related transcription factor 3
chr19_-_55918980 10.053 UBE2S
ubiquitin-conjugating enzyme E2S
chr1_-_245027791 10.049 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr3_+_120461557 10.039 NM_005513
GTF2E1
general transcription factor IIE, polypeptide 1, alpha 56kDa
chr2_-_130939146 9.953 NM_001171083
NM_017751
NM_017951
SMPD4


sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)


chr1_+_181057835 9.936 IER5
immediate early response 5
chr1_+_110527327 9.935 NM_001242673
NM_006621
AHCYL1

adenosylhomocysteinase-like 1

chr1_+_39491966 9.892 NM_001184979
NM_004552
NDUFS5

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)

chr6_-_75994477 9.879 TMEM30A
transmembrane protein 30A
chr4_-_100871418 9.840 H2AFZ
H2A histone family, member Z
chr22_+_20105145 9.824 RANBP1
RAN binding protein 1
chrX_+_70503496 9.749 NONO
non-POU domain containing, octamer-binding
chr3_-_183602633 9.707 PARL
presenilin associated, rhomboid-like
chr19_+_39109831 9.697 EIF3K
eukaryotic translation initiation factor 3, subunit K
chr2_-_225449721 9.653 CUL3
cullin 3
chr1_-_115300615 9.591 NM_001007553
NM_001130523
NM_001242891
NM_001242892
NM_001242893
NM_007158
CSDE1





cold shock domain containing E1, RNA-binding





chr15_-_49447765 9.510 NM_001143887
NM_004236
COPS2

COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)

chr14_+_93651295 9.499 NM_015676
NM_001098621
C14orf109

chromosome 14 open reading frame 109

chr19_+_39109807 9.494 EIF3K
eukaryotic translation initiation factor 3, subunit K
chr20_+_30193083 9.475 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr14_+_24605366 9.444 NM_006263
NM_176783
PSME1

proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)

chr15_-_90777114 9.440 CIB1
calcium and integrin binding 1 (calmyrin)
chr1_-_167905078 9.433 BRP44
brain protein 44
chr11_+_64808395 9.408 SAC3D1
SAC3 domain containing 1
chr16_-_81040439 9.405 NM_020188
C16orf61
chromosome 16 open reading frame 61
chr16_-_84651639 9.397 NM_021149
COTL1
coactosin-like 1 (Dictyostelium)
chrX_+_77359665 9.392 NM_000291
PGK1
phosphoglycerate kinase 1
chr12_+_58120029 9.388 LOC100130776
uncharacterized LOC100130776
chr1_+_45205533 9.343 KIF2C
kinesin family member 2C
chr16_-_66864803 9.336 NAE1
NEDD8 activating enzyme E1 subunit 1
chr3_-_183602658 9.316 PARL
presenilin associated, rhomboid-like
chr19_+_39109847 9.296 EIF3K
eukaryotic translation initiation factor 3, subunit K
chr1_+_116184573 9.253 NM_001172411
NM_138959
VANGL1

vang-like 1 (van gogh, Drosophila)

chr15_-_83735892 9.237 BTBD1
BTB (POZ) domain containing 1
chr3_-_183602646 9.208 PARL
presenilin associated, rhomboid-like
chr6_+_52930160 9.179 FBXO9
F-box protein 9
chrX_+_67718868 9.172 YIPF6
Yip1 domain family, member 6
chr3_-_183602668 9.164 PARL
presenilin associated, rhomboid-like
chr3_-_133380626 9.163 NM_007027
TOPBP1
topoisomerase (DNA) II binding protein 1
chr4_-_174254730 9.155 NM_001130689
HMGB2
high mobility group box 2
chr13_-_113862944 9.129 NM_001127202
NM_001127203
NM_018386
PCID2


PCI domain containing 2


chr11_+_64808375 9.126 NM_013299
SAC3D1
SAC3 domain containing 1
chr12_+_72148653 9.094 NM_014999
RAB21
RAB21, member RAS oncogene family
chr15_-_101835404 9.052 NM_003090
SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr14_-_23058114 9.021 NM_001344
DAD1
defender against cell death 1
chr17_-_56065474 9.020 VEZF1
vascular endothelial zinc finger 1
chr2_+_181845088 8.958 NM_182678
NM_006357
UBE2E3

ubiquitin-conjugating enzyme E2E 3

chr1_-_115300583 8.937 CSDE1
cold shock domain containing E1, RNA-binding
chr5_-_142783975 8.879 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_-_68290114 8.866 C1D
C1D nuclear receptor corepressor
chr7_+_99006544 8.842 NM_003910
BUD31
BUD31 homolog (S. cerevisiae)
chr12_+_124069053 8.814 NM_006815
TMED2
transmembrane emp24 domain trafficking protein 2
chr16_+_57481336 8.812 NM_020312
COQ9
coenzyme Q9 homolog (S. cerevisiae)
chr5_+_72794273 8.685 BTF3
basic transcription factor 3
chr17_-_78120759 8.663 NM_014740
EIF4A3
eukaryotic translation initiation factor 4A3
chr6_-_2245655 8.655 NM_001500
GMDS
GDP-mannose 4,6-dehydratase
chr1_+_62902735 8.637 USP1
ubiquitin specific peptidase 1
chrX_-_20285141 8.613 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr17_-_26972141 8.607 KIAA0100
KIAA0100
chr3_-_183602690 8.600 NM_001037639
NM_018622
PARL

presenilin associated, rhomboid-like

chr12_-_46662533 8.530 SLC38A1
solute carrier family 38, member 1
chr1_-_244615119 8.500 ADSS
adenylosuccinate synthase
chr14_+_78174424 8.478 NM_031210
SLIRP
SRA stem-loop interacting RNA binding protein
chr9_-_130890026 8.477 PTGES2
prostaglandin E synthase 2
chr9_-_33001518 8.463 NM_001195249
NM_001195254
NM_001195248
NM_001195250
NM_001195251
NM_001195252
NM_175069
NM_175073
APTX







aprataxin







chr9_-_132597540 8.452 C9orf78
chromosome 9 open reading frame 78
chr12_-_29534089 8.435 NM_016570
ERGIC2
ERGIC and golgi 2
chr5_-_142783059 8.412 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_-_26972173 8.385 NM_014680
KIAA0100
KIAA0100
chr22_-_42084819 8.344 NM_001003796
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr2_-_68290158 8.314 NM_001190263
NM_001190265
NM_006333
NM_173177
C1D



C1D nuclear receptor corepressor



chrX_-_16888175 8.309 RBBP7
retinoblastoma binding protein 7
chr5_+_141348692 8.305 NM_183401
RNF14
ring finger protein 14
chr12_-_29534082 8.227 ERGIC2
ERGIC and golgi 2
chr4_+_110354971 8.219 SEC24B
SEC24 family, member B (S. cerevisiae)
chr15_-_42565473 8.206 NM_001110503
NM_015497
TMEM87A

transmembrane protein 87A

chr12_-_29534069 8.191 ERGIC2
ERGIC and golgi 2
chr15_+_52311408 8.188 NM_002748
MAPK6
mitogen-activated protein kinase 6
chr12_+_70637210 8.187 CNOT2
CCR4-NOT transcription complex, subunit 2
chr8_-_17104266 8.179 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr13_-_110438896 8.157 NM_003749
IRS2
insulin receptor substrate 2
chrX_-_15872921 8.151 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr1_-_115300601 8.139 CSDE1
cold shock domain containing E1, RNA-binding
chr1_-_28240953 8.132 RPA2
replication protein A2, 32kDa
chr19_-_41858948 8.129 TGFB1
transforming growth factor, beta 1
chr19_+_8509869 8.127 HNRNPM
heterogeneous nuclear ribonucleoprotein M

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.55 1.40e-26 GO:0044237 cellular metabolic process
1.72 3.25e-26 GO:0044260 cellular macromolecule metabolic process
1.46 9.91e-23 GO:0008152 metabolic process
1.26 1.23e-22 GO:0009987 cellular process
1.50 1.45e-22 GO:0044238 primary metabolic process
1.61 7.89e-22 GO:0043170 macromolecule metabolic process
1.85 8.30e-19 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.91 3.90e-16 GO:0090304 nucleic acid metabolic process
1.72 5.59e-16 GO:0034641 cellular nitrogen compound metabolic process
1.70 5.88e-16 GO:0006807 nitrogen compound metabolic process
2.00 2.02e-14 GO:0016070 RNA metabolic process
1.93 2.67e-13 GO:0010467 gene expression
1.72 1.28e-11 GO:0044267 cellular protein metabolic process
1.57 2.66e-11 GO:0071840 cellular component organization or biogenesis
1.55 1.11e-09 GO:0016043 cellular component organization
1.63 1.39e-09 GO:0071841 cellular component organization or biogenesis at cellular level
1.84 4.26e-09 GO:0006996 organelle organization
2.59 5.53e-09 GO:0016071 mRNA metabolic process
1.56 1.10e-08 GO:0019538 protein metabolic process
2.38 3.08e-08 GO:0006396 RNA processing
1.77 7.35e-08 GO:0009059 macromolecule biosynthetic process
1.95 8.54e-08 GO:0044248 cellular catabolic process
1.58 8.71e-08 GO:0071842 cellular component organization at cellular level
1.76 1.29e-07 GO:0034645 cellular macromolecule biosynthetic process
2.14 5.07e-07 GO:0046907 intracellular transport
1.98 5.80e-07 GO:0007049 cell cycle
2.42 7.21e-07 GO:0044265 cellular macromolecule catabolic process
2.65 1.54e-06 GO:0006397 mRNA processing
3.38 1.61e-06 GO:0000375 RNA splicing, via transesterification reactions
2.02 3.93e-06 GO:0015031 protein transport
2.01 3.96e-06 GO:0045184 establishment of protein localization
2.23 5.11e-06 GO:0009057 macromolecule catabolic process
1.79 5.85e-06 GO:0033036 macromolecule localization
2.79 9.93e-06 GO:0008380 RNA splicing
1.73 1.28e-05 GO:0009056 catabolic process
3.26 1.29e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.26 1.29e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
1.82 3.84e-05 GO:0051649 establishment of localization in cell
1.75 5.00e-05 GO:0051641 cellular localization
1.51 5.30e-05 GO:0044249 cellular biosynthetic process
2.14 1.13e-04 GO:0000278 mitotic cell cycle
1.48 1.34e-04 GO:0009058 biosynthetic process
1.92 2.23e-04 GO:0022402 cell cycle process
1.83 2.27e-04 GO:0032774 RNA biosynthetic process
1.78 2.31e-04 GO:0008104 protein localization
2.01 2.57e-04 GO:0022403 cell cycle phase
2.48 3.76e-04 GO:0070647 protein modification by small protein conjugation or removal
1.55 6.91e-04 GO:0006464 protein modification process
2.60 7.88e-04 GO:0010608 posttranscriptional regulation of gene expression
1.53 8.93e-04 GO:0043412 macromolecule modification
1.74 1.57e-03 GO:0042981 regulation of apoptosis
2.12 1.93e-03 GO:0034621 cellular macromolecular complex subunit organization
2.46 2.05e-03 GO:0048285 organelle fission
1.72 2.20e-03 GO:0010941 regulation of cell death
1.72 2.21e-03 GO:0043067 regulation of programmed cell death
2.50 2.75e-03 GO:0032446 protein modification by small protein conjugation
1.82 2.77e-03 GO:0033554 cellular response to stress
2.30 3.66e-03 GO:0051301 cell division
2.19 3.95e-03 GO:0016032 viral reproduction
2.39 5.20e-03 GO:0000087 M phase of mitotic cell cycle
2.19 6.97e-03 GO:0006886 intracellular protein transport
2.39 7.45e-03 GO:0000280 nuclear division
2.39 7.45e-03 GO:0007067 mitosis
1.75 7.99e-03 GO:0006351 transcription, DNA-dependent
1.83 8.38e-03 GO:0012501 programmed cell death
2.37 8.73e-03 GO:0006366 transcription from RNA polymerase II promoter
2.30 9.20e-03 GO:0019941 modification-dependent protein catabolic process
2.75 9.92e-03 GO:0022411 cellular component disassembly
2.75 9.92e-03 GO:0071845 cellular component disassembly at cellular level
2.26 1.00e-02 GO:0044257 cellular protein catabolic process
1.83 1.05e-02 GO:0006915 apoptosis
2.29 1.07e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.74 1.18e-02 GO:0008219 cell death
1.80 1.31e-02 GO:0016192 vesicle-mediated transport
2.44 1.34e-02 GO:0016567 protein ubiquitination
2.08 1.36e-02 GO:0000279 M phase
1.73 1.41e-02 GO:0016265 death
19.78 1.41e-02 GO:0046796 viral genome transport in host cell
1.44 1.43e-02 GO:0048523 negative regulation of cellular process
2.28 1.53e-02 GO:0006511 ubiquitin-dependent protein catabolic process
2.24 1.65e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.88 1.84e-02 GO:0051276 chromosome organization
2.17 1.87e-02 GO:0030163 protein catabolic process
1.60 2.40e-02 GO:0044085 cellular component biogenesis
3.08 2.62e-02 GO:0006403 RNA localization
2.59 2.85e-02 GO:0006457 protein folding
4.08 2.89e-02 GO:0031124 mRNA 3'-end processing
2.01 3.18e-02 GO:0060548 negative regulation of cell death
1.36 3.47e-02 GO:0048518 positive regulation of biological process
2.02 3.53e-02 GO:0043069 negative regulation of programmed cell death
2.68 3.65e-02 GO:0006913 nucleocytoplasmic transport
2.65 4.42e-02 GO:0051169 nuclear transport
1.33 4.98e-02 GO:0051234 establishment of localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 3.47e-44 GO:0044424 intracellular part
1.31 1.53e-41 GO:0005622 intracellular
1.43 4.87e-34 GO:0043231 intracellular membrane-bounded organelle
1.43 7.27e-34 GO:0043227 membrane-bounded organelle
1.37 2.70e-33 GO:0043229 intracellular organelle
1.37 5.43e-33 GO:0043226 organelle
1.44 7.57e-32 GO:0005737 cytoplasm
1.61 3.21e-28 GO:0044446 intracellular organelle part
1.60 8.94e-28 GO:0044422 organelle part
1.51 9.37e-23 GO:0044444 cytoplasmic part
2.00 1.75e-21 GO:0070013 intracellular organelle lumen
1.53 2.83e-21 GO:0005634 nucleus
1.95 1.31e-20 GO:0031974 membrane-enclosed lumen
1.96 2.26e-20 GO:0043233 organelle lumen
1.99 4.33e-20 GO:0044428 nuclear part
1.69 5.18e-19 GO:0032991 macromolecular complex
2.06 5.55e-19 GO:0031981 nuclear lumen
2.19 4.55e-16 GO:0005654 nucleoplasm
1.84 6.32e-14 GO:0005829 cytosol
1.10 1.26e-11 GO:0044464 cell part
1.10 1.30e-11 GO:0005623 cell
1.57 4.86e-10 GO:0043234 protein complex
2.59 1.03e-09 GO:0030529 ribonucleoprotein complex
1.55 2.13e-08 GO:0043228 non-membrane-bounded organelle
1.55 2.13e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.90 2.13e-04 GO:0044451 nucleoplasm part
1.93 2.22e-04 GO:0015630 microtubule cytoskeleton
3.25 3.76e-04 GO:0005681 spliceosomal complex
2.03 8.47e-04 GO:0005730 nucleolus
2.07 9.57e-04 GO:0044427 chromosomal part
1.96 1.09e-03 GO:0005694 chromosome
1.69 1.29e-03 GO:0005794 Golgi apparatus
2.65 4.77e-03 GO:0005819 spindle
7.69 6.01e-03 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.98 6.46e-03 GO:0005768 endosome
1.46 1.42e-02 GO:0012505 endomembrane system
3.51 1.42e-02 GO:0071013 catalytic step 2 spliceosome
1.38 2.39e-02 GO:0031090 organelle membrane
2.70 2.84e-02 GO:0000793 condensed chromosome
4.56 4.19e-02 GO:0005876 spindle microtubule
3.34 4.46e-02 GO:0000779 condensed chromosome, centromeric region
2.26 4.78e-02 GO:0016604 nuclear body
3.15 4.80e-02 GO:0000776 kinetochore

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.49 1.58e-29 GO:0005515 protein binding
1.18 3.95e-12 GO:0005488 binding
2.18 3.15e-09 GO:0003723 RNA binding
1.56 8.27e-07 GO:0000166 nucleotide binding
1.41 9.53e-06 GO:0003676 nucleic acid binding
2.20 9.94e-05 GO:0016874 ligase activity
2.67 3.28e-04 GO:0019787 small conjugating protein ligase activity
1.26 5.80e-04 GO:0003824 catalytic activity
2.50 6.26e-04 GO:0016881 acid-amino acid ligase activity
1.84 6.27e-04 GO:0019899 enzyme binding
1.49 8.52e-04 GO:0035639 purine ribonucleoside triphosphate binding
2.39 8.97e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.47 1.66e-03 GO:0017076 purine nucleotide binding
1.47 2.01e-03 GO:0032553 ribonucleotide binding
1.47 2.01e-03 GO:0032555 purine ribonucleotide binding
2.46 7.62e-03 GO:0004842 ubiquitin-protein ligase activity
1.68 2.15e-02 GO:0016462 pyrophosphatase activity
1.67 2.43e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.69 2.48e-02 GO:0017111 nucleoside-triphosphatase activity
1.66 2.73e-02 GO:0016817 hydrolase activity, acting on acid anhydrides