Motif ID: GATA1..3.p2

Z-value: 2.992


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA2chr3_-_1282067040.276.1e-05Click!
GATA1chrX_+_48644961-0.126.9e-02Click!
GATA3chr10_+_8097350-0.111.1e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_91769329 62.850 SV2B
synaptic vesicle glycoprotein 2B
chrX_+_38420690 42.645 NM_004615
TSPAN7
tetraspanin 7
chr5_-_141993691 40.447 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr19_+_54376975 37.790 MYADM
myeloid-associated differentiation marker
chr12_+_79258588 36.835 SYT1
synaptotagmin I
chr5_+_156820161 35.930 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_-_111782447 33.257 NM_001885
CRYAB
crystallin, alpha B
chrX_-_13835187 32.776 GPM6B
glycoprotein M6B
chr6_-_32095974 31.717 ATF6B
activating transcription factor 6 beta
chr12_+_79258517 31.405 SYT1
synaptotagmin I
chr14_+_65007418 30.953 HSPA2
heat shock 70kDa protein 2
chr7_-_31380507 30.734 NM_022728
NEUROD6
neurogenic differentiation 6
chr6_-_32095993 30.560 NM_001136153
NM_004381
ATF6B

activating transcription factor 6 beta

chr3_-_195310985 30.004 NM_001647
APOD
apolipoprotein D
chr2_+_149632772 28.198 NM_004522
KIF5C
kinesin family member 5C
chr3_+_133494275 27.871 TF
transferrin
chrX_-_153236621 27.318 NM_005334
HCFC1
host cell factor C1 (VP16-accessory protein)
chr4_+_76439653 26.594 NM_144721
THAP6
THAP domain containing 6
chrX_-_13835012 25.195 GPM6B
glycoprotein M6B
chr12_+_79258448 24.584 NM_005639
SYT1
synaptotagmin I
chr7_+_64498643 24.263 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr12_+_79258794 23.787 SYT1
synaptotagmin I
chr2_-_175869910 23.704 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chrX_-_13835313 23.674 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr16_+_3405888 23.669 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr6_-_46825942 23.537 GPR116
G protein-coupled receptor 116
chr6_-_29595746 22.907 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr20_-_48099178 22.780 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr5_+_36608430 22.761 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_60097223 22.460 RTN1
reticulon 1
chr3_-_51993955 22.348 PCBP4
poly(rC) binding protein 4
chr9_+_137967088 22.296 NM_014279
NM_006334
OLFM1

olfactomedin 1

chrX_-_13835213 22.121 GPM6B
glycoprotein M6B
chr4_-_186877869 21.971 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr5_-_146435589 20.649 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr20_+_44657858 20.190 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr3_-_195310770 20.084 APOD
apolipoprotein D
chr19_+_15160194 20.024 NM_012114
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr1_+_50575465 19.866 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr14_-_60097314 19.809 RTN1
reticulon 1
chr1_+_171810611 19.699 NM_001136127
NM_015569
DNM3

dynamin 3

chr6_+_122793061 19.562 NM_181794
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chrX_+_110366304 19.452 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr9_+_137967401 19.447 OLFM1
olfactomedin 1
chr1_+_228645807 19.186 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr3_+_159557649 19.151 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr12_-_49392909 18.975 NM_015086
DDN
dendrin
chr12_+_121088370 18.969 NM_004276
NM_031205
CABP1

calcium binding protein 1

chr1_-_230849863 18.876 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_+_155853546 18.684 SYT11
synaptotagmin XI
chr14_+_29236882 18.532 FOXG1
forkhead box G1
chr3_-_169381417 18.503 NM_001205194
NM_004991
MECOM

MDS1 and EVI1 complex locus

chr17_+_42385780 18.452 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr3_-_10067989 18.426 CIDECP
cell death-inducing DFFA-like effector c pseudogene
chr18_-_74728963 18.394 MBP
myelin basic protein
chr4_+_113739203 18.242 NM_001127493
ANK2
ankyrin 2, neuronal
chr12_+_7282963 18.236 NM_014718
CLSTN3
calsyntenin 3
chr18_-_74729049 18.235 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr1_-_230849847 18.100 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_-_114343791 17.974 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr15_+_43809805 17.974 NM_002373
MAP1A
microtubule-associated protein 1A
chr15_+_71184781 17.797 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr5_-_139944045 17.779 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3



chr7_-_37025696 17.598 ELMO1
engulfment and cell motility 1
chr11_-_35547144 17.576 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr2_+_149632836 17.452 KIF5C
kinesin family member 5C
chr1_-_228645517 17.428 NM_033445
HIST3H2A
histone cluster 3, H2a
chr2_+_149633173 17.371


chr12_+_79439432 17.190 NM_001135806
SYT1
synaptotagmin I
chr2_-_216241321 17.169 FN1
fibronectin 1
chr6_-_62995852 17.151 NM_152688
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr1_+_92632608 17.071 NM_015237
KIAA1107
KIAA1107
chr18_-_53068755 16.921 TCF4
transcription factor 4
chr1_-_177133818 16.839 ASTN1
astrotactin 1
chr8_+_22210311 16.783 PIWIL2
piwi-like 2 (Drosophila)
chr8_+_85097099 16.776 NM_001100391
RALYL
RALY RNA binding protein-like
chr17_-_37764165 16.717 NM_006160
NEUROD2
neurogenic differentiation 2
chrX_-_140271293 16.551 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr1_-_182354649 16.479 GLUL
glutamate-ammonia ligase
chr17_-_56606710 16.401 NM_004574
SEPT4
septin 4
chr6_+_7108864 16.198 RREB1
ras responsive element binding protein 1
chr17_-_7106561 16.042 DLG4
discs, large homolog 4 (Drosophila)
chr3_+_111718006 16.030 NM_001008273
TAGLN3
transgelin 3
chrX_+_69642880 15.872 NM_001171191
NM_001171192
NM_001171193
NM_017711
GDPD2



glycerophosphodiester phosphodiesterase domain containing 2



chr3_-_98241357 15.758 CLDND1
claudin domain containing 1
chr12_-_16758312 15.701 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_159557745 15.657 SCHIP1
schwannomin interacting protein 1
chr16_+_6533758 15.626 RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr3_-_114343052 15.498 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_177133950 15.394 NM_004319
NM_207108
ASTN1

astrotactin 1

chr5_-_138210992 15.385 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr11_-_66639602 15.348


chr19_-_46295647 15.159 DMWD
dystrophia myotonica, WD repeat containing
chr12_-_16757944 15.031 LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_-_3525973 14.921 NM_002919
NM_134428
RFX3

regulatory factor X, 3 (influences HLA class II expression)

chr20_+_44657812 14.906 NM_020708
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chrX_+_103031433 14.889 NM_001128834
PLP1
proteolipid protein 1
chr17_+_7554711 14.839 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr17_+_7554415 14.810 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr17_-_40021616 14.601 NM_018143
KLHL11
kelch-like 11 (Drosophila)
chr3_-_48700317 14.565 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr13_-_45150391 14.556 TSC22D1
TSC22 domain family, member 1
chr7_+_86781644 14.542 NM_001142326
NM_001142327
DMTF1

cyclin D binding myb-like transcription factor 1

chr9_+_124086842 14.477 GSN
gelsolin
chr10_-_123353771 14.453 NM_001144916
FGFR2
fibroblast growth factor receptor 2
chr8_+_28747885 14.436 NM_001135726
HMBOX1
homeobox containing 1
chr8_+_28748030 14.394 NM_024567
HMBOX1
homeobox containing 1
chr5_-_115152322 14.171 NM_001801
CDO1
cysteine dioxygenase, type I
chrX_+_57618440 14.032 ZXDB
zinc finger, X-linked, duplicated B
chr1_+_36023389 14.029 NM_001014839
NM_001014841
NM_014284
NCDN


neurochondrin


chrX_+_103031797 13.996 PLP1
proteolipid protein 1
chr4_+_113970784 13.960 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr4_-_186877413 13.932 SORBS2
sorbin and SH3 domain containing 2
chr16_+_1756161 13.864 NM_001040439
NM_015133
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr14_+_69865380 13.840 NM_001252148
NM_001252150
NM_018375
SLC39A9


solute carrier family 39 (zinc transporter), member 9


chr9_+_137967366 13.795 OLFM1
olfactomedin 1
chrX_+_103031753 13.660 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr8_-_18541441 13.648 PSD3
pleckstrin and Sec7 domain containing 3
chr6_-_46889620 13.635 NM_001098518
GPR116
G protein-coupled receptor 116
chr16_-_30934437 13.627 FBXL19-AS1
FBXL19 antisense RNA 1 (non-protein coding)
chr10_+_104678001 13.514 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr20_-_43883183 13.510 NM_003064
SLPI
secretory leukocyte peptidase inhibitor
chr16_-_29910340 13.475 NM_001114099
NM_001114100
NM_001243332
NM_001243333
NM_012410
NM_201575
SEZ6L2





seizure related 6 homolog (mouse)-like 2





chr16_-_28303366 13.378


chr3_-_47621729 13.319 NM_001206942
NM_001206945
CSPG5

chondroitin sulfate proteoglycan 5 (neuroglycan C)

chr11_-_117166247 13.317 NM_001207048
NM_001207049
BACE1

beta-site APP-cleaving enzyme 1

chr17_+_26711510 13.275 SARM1
sterile alpha and TIR motif containing 1
chr1_+_155829259 13.261 NM_152280
SYT11
synaptotagmin XI
chr1_+_27719151 13.241 NM_005281
GPR3
G protein-coupled receptor 3
chr2_-_216259197 13.213 FN1
fibronectin 1
chrX_-_140271275 13.086 LDOC1
leucine zipper, down-regulated in cancer 1
chr17_-_42992852 13.008 NM_001131019
NM_001242376
NM_002055
GFAP


glial fibrillary acidic protein


chr6_+_43266008 12.996 SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr11_+_131240370 12.961 NM_001048209
NTM
neurotrimin
chr20_-_44563684 12.899 FLJ40606
uncharacterized LOC643549
chr2_+_189839113 12.788 COL3A1
collagen, type III, alpha 1
chr9_+_74526527 12.734 C9orf85
chromosome 9 open reading frame 85
chr9_+_139872014 12.672 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr7_+_39017608 12.612 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr1_-_113161724 12.447 NM_017744
NM_138727
NM_138728
NM_138729
ST7L



suppression of tumorigenicity 7 like



chr10_-_104473957 12.434 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr11_-_85469043 12.381 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr10_-_73848263 12.369 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr2_-_145274916 12.324 ZEB2
zinc finger E-box binding homeobox 2
chr1_+_180601121 12.254 NM_001135669
NM_004736
XPR1

xenotropic and polytropic retrovirus receptor 1

chr2_+_189839078 12.239 NM_000090
COL3A1
collagen, type III, alpha 1
chr2_-_209010876 12.226 NM_005210
CRYGB
crystallin, gamma B
chr12_-_16760935 12.210 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr11_-_5271035 12.204 NM_000559
HBG1
hemoglobin, gamma A
chr17_+_30814708 12.185


chrX_+_70364707 12.150 NLGN3
neuroligin 3
chr2_+_189839132 12.150 COL3A1
collagen, type III, alpha 1
chr19_-_50316360 12.104 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr17_+_30814552 12.103 CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr17_-_56406120 12.089 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr17_-_28257017 12.044 NM_033389
SSH2
slingshot homolog 2 (Drosophila)
chr21_+_27012067 11.958 JAM2
junctional adhesion molecule 2
chr4_-_109684053 11.913 NM_001146590
NM_001146627
NM_031279
AGXT2L1


alanine-glyoxylate aminotransferase 2-like 1


chr6_-_33285493 11.866 NM_005453
ZBTB22
zinc finger and BTB domain containing 22
chr5_-_139943829 11.753 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chrX_+_70315637 11.717 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr5_-_138211054 11.602 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr9_-_34710062 11.558 NM_002989
CCL21
chemokine (C-C motif) ligand 21
chr19_-_49944613 11.534 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr13_-_45150601 11.531 NM_001243799
NM_183422
TSC22D1

TSC22 domain family, member 1

chrX_+_110187468 11.506 NM_001128166
NM_001128167
PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

chr17_+_28256873 11.490 NM_001145053
EFCAB5
EF-hand calcium binding domain 5
chr5_+_170736287 11.488 NM_021025
TLX3
T-cell leukemia homeobox 3
chr15_+_34261088 11.351 NM_012125
CHRM5
cholinergic receptor, muscarinic 5
chr17_-_8066254 11.338 NM_014232
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr8_+_26371461 11.312 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chrX_+_70364728 11.279 NLGN3
neuroligin 3
chr11_-_72380107 11.268 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr17_-_56606534 11.253 SEPT4
septin 4
chr20_+_10199455 11.252 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr6_-_80656870 11.249 NM_022726
ELOVL4
ELOVL fatty acid elongase 4
chrX_+_57618268 11.248 NM_007157
ZXDB
zinc finger, X-linked, duplicated B
chr5_-_88178964 11.242 MEF2C
myocyte enhancer factor 2C
chr8_-_38854025 11.226 NM_001024380
NM_001024381
NM_031940
NM_078473
TM2D2



TM2 domain containing 2



chr4_-_186733372 11.211 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr3_+_111717585 11.184 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr9_+_139871954 11.154 NM_000954
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr4_-_176734181 11.132 NM_201591
GPM6A
glycoprotein M6A
chr7_+_86781869 11.103 NM_021145
DMTF1
cyclin D binding myb-like transcription factor 1
chr4_-_186732047 11.075 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr6_+_43265994 11.050 NM_006672
NM_153320
SLC22A7

solute carrier family 22 (organic anion transporter), member 7

chr7_-_137028275 11.031 PTN
pleiotrophin
chr6_-_90024936 10.999 NM_002043
GABRR2
gamma-aminobutyric acid (GABA) receptor, rho 2
chr8_+_9413390 10.969 TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr7_-_137028433 10.958 PTN
pleiotrophin
chr1_+_24969766 10.941 SRRM1
serine/arginine repetitive matrix 1
chr18_+_55102777 10.928 NM_004852
ONECUT2
one cut homeobox 2
chr11_+_33563772 10.882 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr3_+_10068123 10.863 FANCD2
Fanconi anemia, complementation group D2
chr2_-_217540722 10.861 IGFBP5
insulin-like growth factor binding protein 5
chr10_+_74451838 10.806 NM_138357
MCU
mitochondrial calcium uniporter
chr5_-_149669187 10.798 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr9_+_130965666 10.768 DNM1
dynamin 1
chr3_-_98241748 10.745 CLDND1
claudin domain containing 1
chr5_+_31799030 10.714 NM_178140
PDZD2
PDZ domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.34 2.47e-37 GO:0032501 multicellular organismal process
1.48 1.61e-32 GO:0048731 system development
1.14 5.51e-32 GO:0009987 cellular process
1.44 7.14e-32 GO:0048856 anatomical structure development
2.00 6.52e-31 GO:0007267 cell-cell signaling
1.39 1.43e-30 GO:0032502 developmental process
1.65 9.59e-28 GO:0007399 nervous system development
1.37 1.01e-27 GO:0023052 signaling
1.38 8.94e-27 GO:0007275 multicellular organismal development
1.20 3.30e-24 GO:0065007 biological regulation
1.49 9.27e-24 GO:0048869 cellular developmental process
1.75 9.98e-24 GO:0007154 cell communication
1.50 3.05e-23 GO:0030154 cell differentiation
1.71 6.94e-19 GO:0022008 neurogenesis
1.99 9.94e-19 GO:0019226 transmission of nerve impulse
1.99 9.94e-19 GO:0035637 multicellular organismal signaling
1.43 2.05e-18 GO:0065008 regulation of biological quality
1.72 6.38e-18 GO:0048699 generation of neurons
1.18 7.06e-18 GO:0050789 regulation of biological process
1.21 8.25e-18 GO:0050896 response to stimulus
2.02 2.12e-17 GO:0007268 synaptic transmission
1.56 2.73e-17 GO:0051239 regulation of multicellular organismal process
1.76 6.79e-16 GO:0030182 neuron differentiation
1.18 9.34e-16 GO:0050794 regulation of cellular process
1.84 1.43e-15 GO:0048666 neuron development
1.30 1.51e-15 GO:0007165 signal transduction
1.25 3.62e-14 GO:0051716 cellular response to stimulus
1.47 3.66e-14 GO:0009653 anatomical structure morphogenesis
1.61 7.73e-14 GO:0048468 cell development
1.40 1.63e-13 GO:0048513 organ development
1.42 3.56e-13 GO:0003008 system process
1.58 2.68e-12 GO:0050793 regulation of developmental process
1.65 2.97e-12 GO:2000026 regulation of multicellular organismal development
1.35 3.11e-12 GO:0042221 response to chemical stimulus
1.70 1.14e-11 GO:0032989 cellular component morphogenesis
1.38 1.87e-11 GO:0007166 cell surface receptor linked signaling pathway
1.70 3.52e-11 GO:0000902 cell morphogenesis
1.77 4.24e-11 GO:0048858 cell projection morphogenesis
1.67 5.30e-11 GO:0030030 cell projection organization
1.82 7.97e-11 GO:0048667 cell morphogenesis involved in neuron differentiation
1.75 1.00e-10 GO:0032990 cell part morphogenesis
1.76 1.13e-10 GO:0000904 cell morphogenesis involved in differentiation
1.80 1.69e-10 GO:0048812 neuron projection morphogenesis
1.76 1.96e-10 GO:0031175 neuron projection development
1.82 2.28e-10 GO:0007409 axonogenesis
1.63 3.01e-10 GO:0045595 regulation of cell differentiation
1.54 1.50e-09 GO:0040011 locomotion
1.91 5.84e-09 GO:0022603 regulation of anatomical structure morphogenesis
1.33 1.67e-08 GO:0048583 regulation of response to stimulus
1.72 1.84e-08 GO:0051094 positive regulation of developmental process
1.49 3.25e-08 GO:0009611 response to wounding
1.26 7.51e-08 GO:0048518 positive regulation of biological process
1.34 1.31e-07 GO:0023051 regulation of signaling
1.80 2.02e-07 GO:0007411 axon guidance
1.60 2.10e-07 GO:0050878 regulation of body fluid levels
1.21 2.26e-07 GO:0051179 localization
1.64 2.27e-07 GO:0007417 central nervous system development
1.81 3.09e-07 GO:0060284 regulation of cell development
1.77 7.23e-07 GO:0044057 regulation of system process
1.26 1.05e-06 GO:0048519 negative regulation of biological process
1.45 1.85e-06 GO:0006811 ion transport
1.42 2.96e-06 GO:0009605 response to external stimulus
1.26 5.02e-06 GO:0048523 negative regulation of cellular process
1.59 5.69e-06 GO:0007599 hemostasis
1.73 6.41e-06 GO:0045597 positive regulation of cell differentiation
1.54 8.00e-06 GO:0042060 wound healing
1.58 9.21e-06 GO:0006935 chemotaxis
1.58 9.21e-06 GO:0042330 taxis
1.41 9.79e-06 GO:0032879 regulation of localization
1.58 1.29e-05 GO:0007596 blood coagulation
1.58 1.29e-05 GO:0050817 coagulation
2.16 1.37e-05 GO:0042391 regulation of membrane potential
1.33 1.47e-05 GO:0050877 neurological system process
1.24 1.97e-05 GO:0048522 positive regulation of cellular process
1.42 2.28e-05 GO:0009888 tissue development
1.19 2.83e-05 GO:0016043 cellular component organization
1.54 3.00e-05 GO:0007186 G-protein coupled receptor protein signaling pathway
3.92 4.02e-05 GO:0022029 telencephalon cell migration
1.58 4.04e-05 GO:0050801 ion homeostasis
1.20 6.91e-05 GO:0006810 transport
1.50 7.08e-05 GO:0009887 organ morphogenesis
1.92 1.07e-04 GO:0003012 muscle system process
1.31 1.08e-04 GO:0009966 regulation of signal transduction
1.96 1.14e-04 GO:0006936 muscle contraction
1.69 1.14e-04 GO:0007610 behavior
3.75 1.26e-04 GO:0021885 forebrain cell migration
2.95 1.33e-04 GO:0003073 regulation of systemic arterial blood pressure
1.20 1.41e-04 GO:0051234 establishment of localization
1.36 1.58e-04 GO:0010646 regulation of cell communication
4.18 2.09e-04 GO:0021795 cerebral cortex cell migration
1.78 2.77e-04 GO:0030168 platelet activation
1.29 2.88e-04 GO:0065009 regulation of molecular function
1.42 3.04e-04 GO:0007155 cell adhesion
1.42 3.04e-04 GO:0022610 biological adhesion
1.46 3.89e-04 GO:0048878 chemical homeostasis
1.56 5.43e-04 GO:0016477 cell migration
1.17 6.96e-04 GO:0071840 cellular component organization or biogenesis
1.76 6.98e-04 GO:0007601 visual perception
1.76 6.98e-04 GO:0050953 sensory perception of light stimulus
1.54 7.14e-04 GO:0032583 regulation of gene-specific transcription
2.14 7.19e-04 GO:0006836 neurotransmitter transport
1.69 7.26e-04 GO:0051960 regulation of nervous system development
1.54 8.38e-04 GO:0006873 cellular ion homeostasis
1.40 8.58e-04 GO:0071844 cellular component assembly at cellular level
1.37 1.02e-03 GO:0006351 transcription, DNA-dependent
1.72 1.02e-03 GO:0050767 regulation of neurogenesis
2.28 1.03e-03 GO:0008016 regulation of heart contraction
1.53 1.09e-03 GO:0055082 cellular chemical homeostasis
1.58 1.48e-03 GO:0007420 brain development
1.96 1.50e-03 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger
2.07 1.67e-03 GO:0019933 cAMP-mediated signaling
1.63 1.67e-03 GO:0006140 regulation of nucleotide metabolic process
1.85 1.74e-03 GO:0030900 forebrain development
2.12 1.77e-03 GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger
2.86 1.86e-03 GO:0021987 cerebral cortex development
1.19 2.04e-03 GO:0071842 cellular component organization at cellular level
3.32 2.11e-03 GO:0007632 visual behavior
1.46 2.40e-03 GO:0006928 cellular component movement
1.35 2.61e-03 GO:0042592 homeostatic process
1.89 2.74e-03 GO:0019935 cyclic-nucleotide-mediated signaling
1.32 2.76e-03 GO:0022607 cellular component assembly
1.52 3.29e-03 GO:0008285 negative regulation of cell proliferation
1.20 3.80e-03 GO:0006950 response to stress
1.49 3.86e-03 GO:0048870 cell motility
1.49 3.86e-03 GO:0051674 localization of cell
1.47 5.07e-03 GO:0030001 metal ion transport
1.45 5.67e-03 GO:0080134 regulation of response to stress
1.46 6.26e-03 GO:0001775 cell activation
1.43 6.63e-03 GO:0006812 cation transport
1.39 6.95e-03 GO:0010628 positive regulation of gene expression
1.54 7.05e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.74 7.13e-03 GO:0045664 regulation of neuron differentiation
2.01 7.32e-03 GO:0003001 generation of a signal involved in cell-cell signaling
2.01 7.32e-03 GO:0023061 signal release
1.31 9.94e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.09 1.06e-02 GO:0021537 telencephalon development
1.97 1.12e-02 GO:0030817 regulation of cAMP biosynthetic process
1.89 1.16e-02 GO:0006112 energy reserve metabolic process
1.74 1.17e-02 GO:0043408 regulation of MAPKKK cascade
1.74 1.17e-02 GO:0048732 gland development
1.34 1.25e-02 GO:0051128 regulation of cellular component organization
1.46 1.37e-02 GO:0009628 response to abiotic stimulus
1.95 1.48e-02 GO:0030814 regulation of cAMP metabolic process
1.90 1.58e-02 GO:0030799 regulation of cyclic nucleotide metabolic process
2.66 1.64e-02 GO:0051899 membrane depolarization
1.62 1.66e-02 GO:0008361 regulation of cell size
1.36 1.66e-02 GO:0051049 regulation of transport
2.08 1.66e-02 GO:0001505 regulation of neurotransmitter levels
1.51 1.69e-02 GO:0090066 regulation of anatomical structure size
1.90 1.85e-02 GO:0030802 regulation of cyclic nucleotide biosynthetic process
1.90 1.85e-02 GO:0030808 regulation of nucleotide biosynthetic process
1.47 2.02e-02 GO:0060341 regulation of cellular localization
1.27 2.25e-02 GO:0050790 regulation of catalytic activity
1.59 2.36e-02 GO:0061061 muscle structure development
1.36 2.36e-02 GO:0009790 embryo development
1.37 2.64e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.56 2.74e-02 GO:0019932 second-messenger-mediated signaling
1.81 2.82e-02 GO:0046883 regulation of hormone secretion
1.17 2.85e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.30 2.98e-02 GO:0042127 regulation of cell proliferation
1.33 3.55e-02 GO:0055085 transmembrane transport
1.77 3.98e-02 GO:0048562 embryonic organ morphogenesis
1.62 4.41e-02 GO:0048568 embryonic organ development
1.51 4.49e-02 GO:0007389 pattern specification process
1.68 4.57e-02 GO:0007517 muscle organ development
3.72 4.61e-02 GO:0014047 glutamate secretion
1.29 4.72e-02 GO:0032774 RNA biosynthetic process
1.32 4.77e-02 GO:0048584 positive regulation of response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.43 2.08e-20 GO:0044459 plasma membrane part
1.99 2.61e-16 GO:0043005 neuron projection
1.98 3.97e-16 GO:0045202 synapse
1.57 1.60e-12 GO:0042995 cell projection
1.46 3.35e-12 GO:0031226 intrinsic to plasma membrane
1.46 5.20e-12 GO:0005887 integral to plasma membrane
1.92 2.68e-10 GO:0044456 synapse part
1.19 1.76e-08 GO:0005886 plasma membrane
1.18 3.93e-08 GO:0071944 cell periphery
2.08 4.12e-08 GO:0030424 axon
1.40 5.00e-08 GO:0000267 cell fraction
1.55 1.59e-07 GO:0030054 cell junction
1.45 4.12e-07 GO:0005626 insoluble fraction
1.45 7.29e-07 GO:0005624 membrane fraction
1.94 1.35e-06 GO:0030425 dendrite
2.47 7.19e-06 GO:0033267 axon part
1.83 1.34e-05 GO:0034702 ion channel complex
2.03 2.39e-05 GO:0034703 cation channel complex
1.57 2.83e-05 GO:0044463 cell projection part
1.95 4.87e-05 GO:0045211 postsynaptic membrane
1.85 1.36e-04 GO:0043025 neuronal cell body
1.38 2.73e-04 GO:0031410 cytoplasmic vesicle
1.39 2.82e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.38 2.83e-04 GO:0031988 membrane-bounded vesicle
1.37 2.91e-04 GO:0005615 extracellular space
1.37 3.45e-04 GO:0031982 vesicle
1.80 4.36e-04 GO:0044297 cell body
1.31 5.68e-04 GO:0044421 extracellular region part
2.05 9.78e-04 GO:0019717 synaptosome
1.56 2.69e-03 GO:0015629 actin cytoskeleton
1.53 2.97e-03 GO:0044433 cytoplasmic vesicle part
2.33 1.34e-02 GO:0044309 neuron spine
2.80 1.44e-02 GO:0034704 calcium channel complex
3.14 1.61e-02 GO:0005891 voltage-gated calcium channel complex
1.53 1.82e-02 GO:0030659 cytoplasmic vesicle membrane
1.52 2.05e-02 GO:0012506 vesicle membrane
2.33 2.16e-02 GO:0043197 dendritic spine
1.07 2.29e-02 GO:0005737 cytoplasm
1.93 3.55e-02 GO:0008021 synaptic vesicle
2.62 4.25e-02 GO:0043204 perikaryon

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 5.24e-18 GO:0005515 protein binding
1.08 1.68e-12 GO:0005488 binding
1.52 6.55e-12 GO:0005102 receptor binding
1.65 5.75e-07 GO:0015267 channel activity
1.41 6.49e-07 GO:0001071 nucleic acid binding transcription factor activity
1.41 6.49e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.65 6.89e-07 GO:0022803 passive transmembrane transporter activity
1.50 7.54e-07 GO:0043565 sequence-specific DNA binding
1.38 8.06e-06 GO:0030528 transcription regulator activity
1.70 8.92e-06 GO:0022836 gated channel activity
1.60 1.75e-05 GO:0022838 substrate-specific channel activity
1.60 2.42e-05 GO:0005216 ion channel activity
1.35 4.01e-05 GO:0022892 substrate-specific transporter activity
1.36 6.21e-05 GO:0022857 transmembrane transporter activity
1.41 8.59e-05 GO:0015075 ion transmembrane transporter activity
1.31 9.25e-05 GO:0005215 transporter activity
1.37 1.01e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.69 1.13e-04 GO:0005261 cation channel activity
1.78 1.94e-04 GO:0000975 regulatory region DNA binding
1.78 1.94e-04 GO:0001067 regulatory region nucleic acid binding
1.78 1.94e-04 GO:0044212 transcription regulatory region DNA binding
1.93 3.31e-04 GO:0022843 voltage-gated cation channel activity
1.78 3.95e-04 GO:0010843 promoter binding
3.38 8.25e-04 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
1.90 9.85e-04 GO:0005516 calmodulin binding
1.42 1.80e-03 GO:0008324 cation transmembrane transporter activity
3.25 1.87e-03 GO:0004112 cyclic-nucleotide phosphodiesterase activity
3.81 3.16e-03 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
1.37 3.47e-03 GO:0005509 calcium ion binding
1.96 1.92e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.66 2.11e-02 GO:0005244 voltage-gated ion channel activity
1.66 2.11e-02 GO:0022832 voltage-gated channel activity
1.50 4.93e-02 GO:0005083 small GTPase regulator activity