Motif ID: GAUAUGU

Z-value: 0.404


Mature miRNA associated with seed GAUAUGU:

NamemiRBase Accession
hsa-miR-190 MIMAT0000458
hsa-miR-190b MIMAT0004929



Activity profile for motif GAUAUGU.

activity profile for motif GAUAUGU


Sorted Z-values histogram for motif GAUAUGU

Sorted Z-values for motif GAUAUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GAUAUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_109683457 2.094 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chrX_-_109561314 1.535 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr19_-_1652327 1.515 NM_003200
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr19_-_1650246 1.433 NM_001136139
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr20_+_9049660 1.323 NM_001172646
PLCB4
phospholipase C, beta 4
chr20_+_9288446 1.309 NM_000933
PLCB4
phospholipase C, beta 4
chr7_+_117824085 1.285 NM_016200
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr1_-_212004113 1.283 NM_014873
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr20_+_9198036 1.249 NM_182797
PLCB4
phospholipase C, beta 4
chr3_+_187943192 1.149 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_-_61765394 1.146 NM_003400
XPO1
exportin 1 (CRM1 homolog, yeast)
chr18_-_53255734 1.118 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr17_-_47439326 1.056 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chrX_-_33229428 1.053 NM_004006
DMD
dystrophin
chr3_+_187930720 1.042 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_183604885 1.040 NM_005717
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr3_+_180630054 0.816 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chr8_-_93029864 0.791 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_+_36050885 0.748 NM_001204197
NBEA
neurobeachin
chr5_-_88119604 0.724 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr12_-_123834984 0.715 NM_001167856
NM_018183
SBNO1

strawberry notch homolog 1 (Drosophila)

chr5_-_88199868 0.706 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chrX_-_33357725 0.697 NM_000109
DMD
dystrophin
chr10_+_97515408 0.685 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr3_+_171757413 0.679 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr12_-_25403824 0.675 NM_004985
NM_033360
KRAS

v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

chr1_-_52456292 0.669 NM_002867
RAB3B
RAB3B, member RAS oncogene family
chr14_-_95599794 0.655 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr9_-_14314036 0.644 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr1_-_42801529 0.627 NM_001198850
FOXJ3
forkhead box J3
chr1_-_37980338 0.610 NM_022756
MEAF6
MYST/Esa1-associated factor 6
chr17_+_75181294 0.591 NM_001144001
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr20_+_56964162 0.591 NM_001195677
NM_004738
VAPB

VAMP (vesicle-associated membrane protein)-associated protein B and C

chr22_-_18256748 0.570 NM_001244572
NM_197966
BID

BH3 interacting domain death agonist

chr8_-_103876390 0.566 NM_015878
NM_148174
AZIN1

antizyme inhibitor 1

chrX_-_31526414 0.558 NM_004014
DMD
dystrophin
chr8_-_93111915 0.556 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_14398981 0.526 NM_001190738
NFIB
nuclear factor I/B
chr3_+_187871473 0.524 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr22_+_25202135 0.514 NM_001039948
NM_001098497
NM_001098498
NM_133454
SGSM1



small G protein signaling modulator 1



chr2_+_201997687 0.510 NM_001202518
CFLAR
CASP8 and FADD-like apoptosis regulator
chr8_-_93115453 0.492 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr8_-_93107881 0.487 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr18_-_25757351 0.466 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr1_-_225840660 0.457 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr8_-_93107442 0.451 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr3_+_171758289 0.450 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr17_+_75085234 0.449 NM_001204410
SEC14L1
LINC00338
SEC14-like 1 (S. cerevisiae)
long intergenic non-protein coding RNA 338
chr11_-_70935807 0.447 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr12_+_4430346 0.443 NM_020375
C12orf5
chromosome 12 open reading frame 5
chrX_-_33146543 0.436 NM_004010
NM_004009
DMD

dystrophin

chrX_-_124097601 0.428 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1 (Drosophila)


chr2_-_47143250 0.424 NM_001171507
NM_001171510
MCFD2

multiple coagulation factor deficiency 2

chr8_-_93075190 0.421 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_152011630 0.414 NM_001122742
ESR1
estrogen receptor 1
chrX_-_6146655 0.412 NM_181332
NLGN4X
neuroligin 4, X-linked
chr12_-_102872329 0.405 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr22_+_40573879 0.395 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr10_+_97471535 0.388 NM_001098175
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chrX_-_20284708 0.388 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr8_-_23712297 0.378 NM_003155
STC1
stanniocalcin 1
chr2_-_47142950 0.377 NM_001171506
NM_001171509
NM_139279
MCFD2


multiple coagulation factor deficiency 2


chr22_-_18257238 0.371 NM_001196
NM_001244569
NM_001244570
NM_197967
NM_001244567
BID




BH3 interacting domain death agonist




chr17_+_75136985 0.363 NM_001039573
NM_001143998
NM_001143999
NM_003003
SEC14L1



SEC14-like 1 (S. cerevisiae)



chr4_-_164534656 0.356 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr6_-_132834165 0.351 NM_003569
STX7
syntaxin 7
chr6_+_152128453 0.347 NM_001122740
ESR1
estrogen receptor 1
chr2_-_214015053 0.335 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_-_118810712 0.325 NM_016281
TAOK3
TAO kinase 3
chr12_-_31743822 0.323 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr2_+_228336877 0.320 NM_001135187
NM_001135188
NM_001135189
NM_004504
AGFG1



ArfGAP with FG repeats 1



chr19_-_53394598 0.317 NM_207333
ZNF320
zinc finger protein 320
chr14_-_95623665 0.316 NM_177438
DICER1
dicer 1, ribonuclease type III
chr9_+_79056581 0.312 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr14_-_95608054 0.310 NM_030621
DICER1
dicer 1, ribonuclease type III
chr18_+_42260774 0.307 NM_015559
SETBP1
SET binding protein 1
chr22_+_40440664 0.295 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr6_+_152126807 0.287 NM_001122741
ESR1
estrogen receptor 1
chr9_+_79115548 0.275 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr2_+_9346876 0.270 NM_001135191
NM_003887
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr4_-_165304406 0.270 NM_001166373
MARCH1
membrane-associated ring finger (C3HC4) 1
chr3_-_24536176 0.269 NM_000461
NM_001128176
NM_001128177
NM_001252634
THRB



thyroid hormone receptor, beta



chr5_-_88179278 0.267 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr7_+_50344255 0.263 NM_001220765
NM_001220766
NM_001220767
NM_001220768
NM_001220769
NM_001220770
NM_001220771
NM_001220772
NM_001220773
NM_001220774
NM_001220775
NM_001220776
NM_006060
IKZF1












IKAROS family zinc finger 1 (Ikaros)












chr9_+_79074067 0.243 NM_001097633
NM_001490
GCNT1

glucosaminyl (N-acetyl) transferase 1, core 2

chr14_+_78870092 0.235 NM_004796
NRXN3
neurexin 3
chr16_+_12995454 0.228 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr12_+_27397077 0.212 NM_015000
STK38L
serine/threonine kinase 38 like
chr9_+_79093256 0.206 NM_001097635
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr18_+_13611664 0.200 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr1_-_42800623 0.200 NM_001198851
FOXJ3
forkhead box J3
chr3_+_11313975 0.188 NM_001136031
NM_001144912
NM_006395
ATG7


ATG7 autophagy related 7 homolog (S. cerevisiae)


chr1_-_42800883 0.180 NM_001198852
FOXJ3
forkhead box J3
chr2_-_47168902 0.172 NM_001171508
NM_001171511
MCFD2

multiple coagulation factor deficiency 2

chr2_-_203736223 0.165 NM_138468
ICA1L
islet cell autoantigen 1,69kDa-like
chr3_+_173116243 0.163 NM_014932
NLGN1
neuroligin 1
chr6_-_166075520 0.158 NM_006661
NM_001130690
PDE10A

phosphodiesterase 10A

chr10_-_91405320 0.154 NM_148977
PANK1
pantothenate kinase 1
chr12_+_74931550 0.153 NM_001136262
ATXN7L3B
ataxin 7-like 3B
chr14_+_55221505 0.149 NM_001161577
SAMD4A
sterile alpha motif domain containing 4A
chr1_+_167691156 0.145 NM_001146191
NM_003953
NM_024569
MPZL1


myelin protein zero-like 1


chr2_+_166326156 0.135 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr9_-_79009265 0.135 NM_018339
RFK
riboflavin kinase
chr10_-_116444374 0.124 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr1_-_42800902 0.124 NM_014947
FOXJ3
forkhead box J3
chrX_-_32173585 0.121 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr3_-_160283361 0.117 NM_002268
KPNA4
karyopherin alpha 4 (importin alpha 3)
chrX_-_6145887 0.115 NM_020742
NLGN4X
neuroligin 4, X-linked
chr11_-_70507911 0.114 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr10_-_116418056 0.111 NM_002313
ABLIM1
actin binding LIM protein 1
chr8_-_18666295 0.105 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr10_-_116286661 0.104 NM_006720
ABLIM1
actin binding LIM protein 1
chrX_-_31284946 0.104 NM_004015
NM_004016
NM_004017
NM_004018
NM_004019
DMD




dystrophin




chr7_-_115670828 0.099 NM_001018058
NM_012252
TFEC

transcription factor EC

chr11_-_31832855 0.090 NM_000280
NM_001604
PAX6

paired box 6

chr21_+_35014624 0.081 NM_001001132
NM_003024
ITSN1

intersectin 1 (SH3 domain protein)

chr6_-_91006580 0.081 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr21_-_40033617 0.079 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chr11_-_31839447 0.079 NM_001127612
PAX6
paired box 6
chr6_+_139456240 0.058 NM_016217
HECA
headcase homolog (Drosophila)
chr4_-_39979549 0.039 NM_001100399
NM_001100400
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr7_-_93189121 0.028 NM_001164738
CALCR
calcitonin receptor
chr6_-_109762373 0.026 NM_001111298
NM_173672
PPIL6

peptidylprolyl isomerase (cyclophilin)-like 6

chr12_+_54426831 0.025 NM_018953
HOXC5
homeobox C5
chr13_+_35516390 0.022 NM_015678
NBEA
neurobeachin
chr17_-_8534008 0.019 NM_005964
MYH10
myosin, heavy chain 10, non-muscle
chr8_-_18871163 0.019 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chr5_+_140579182 0.016 NM_018931
PCDHB11
protocadherin beta 11
chr2_+_166428845 0.011 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
27.08 6.54e-03 GO:0007416 synapse assembly
6.55 4.57e-02 GO:0046578 regulation of Ras protein signal transduction
16.67 4.59e-02 GO:0050808 synapse organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
6.71 2.01e-05 GO:0045202 synapse
3.83 2.76e-02 GO:0030054 cell junction

Nothing significant found in function category.