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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: GFI1.p2

Z-value: 1.947

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_+_172468469	33.767		ECT2	epithelial cell transforming sequence 2 oncogene
chr19_-_14247267	28.288		ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr19_-_14247400	26.128	NM_018154	ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr9_+_91926109	23.486	NM_001827	CKS2	CDC28 protein kinase regulatory subunit 2
chr14_-_55658205	23.014	NM_001146015 NM_014750	DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr17_-_38574042	22.942	NM_001067	TOP2A	topoisomerase (DNA) II alpha 170kDa
chr12_-_120315074	19.586	NM_001206999 NM_007174	CIT	citron (rho-interacting, serine/threonine kinase 21)
chr12_+_104324157	19.554		HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr8_-_25315941	18.777	NM_017634	KCTD9	potassium channel tetramerisation domain containing 9
chrX_-_107334749	18.737	NM_002814 NM_170750	PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chrX_+_154444700	18.343	NM_003372	VBP1	von Hippel-Lindau binding protein 1
chr12_+_104324192	17.652		HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr1_+_62902325	17.468	NM_003368	USP1	ubiquitin specific peptidase 1
chr17_-_76183074	17.451	NM_003258	TK1	thymidine kinase 1, soluble
chr8_-_101964248	16.639		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr8_-_101964247	16.516		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr12_+_104324214	16.437		HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr8_-_101964268	16.354		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr8_-_101964236	16.216		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr12_+_104324186	16.037	NM_003299	HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr8_-_101964258	15.775		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr16_-_69760354	15.480		NQO1	NAD(P)H dehydrogenase, quinone 1
chr8_-_101964197	15.444		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr1_-_68962679	15.249		DEPDC1	DEP domain containing 1
chr6_-_38670882	15.115		GLO1	glyoxalase I
chr6_-_38670904	14.746		GLO1	glyoxalase I
chr2_+_47630291	14.678		MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr12_-_102513846	14.552		NUP37	nucleoporin 37kDa
chr6_-_38670922	14.423	NM_006708	GLO1	glyoxalase I
chr2_+_47630190	14.397		MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chrX_+_119737905	14.352		MCTS1	malignant T cell amplified sequence 1
chr2_+_47630246	14.292	NM_000251	MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chrX_+_119737984	14.275		MCTS1	malignant T cell amplified sequence 1
chr14_+_54863672	14.274	NM_001130851 NM_005192	CDKN3	cyclin-dependent kinase inhibitor 3
chr12_+_96252770	14.040		SNRPF	small nuclear ribonucleoprotein polypeptide F
chr12_+_64803741	14.014		XPOT	exportin, tRNA (nuclear export receptor for tRNAs)
chr12_+_96252705	13.834	NM_003095	SNRPF	small nuclear ribonucleoprotein polypeptide F
chr16_+_23690160	13.655		PLK1	polo-like kinase 1
chr16_+_23690212	13.558		PLK1	polo-like kinase 1
chr6_-_38670829	13.045		GLO1	glyoxalase I
chr16_+_23690234	12.773		PLK1	polo-like kinase 1
chrX_-_13835012	12.646		GPM6B	glycoprotein M6B
chr16_+_23690191	12.589	NM_005030	PLK1	polo-like kinase 1
chr16_+_89989686	12.527	NM_006086	TUBB3	tubulin, beta 3 class III
chr20_-_54967221	12.413	NM_003600 NM_198433 NM_198434 NM_198435 NM_198436 NM_198437	AURKA	aurora kinase A
chr16_+_23690190	12.110		PLK1	polo-like kinase 1
chr14_-_64010087	11.925		PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr19_-_55919324	11.846	NM_014501	UBE2S	ubiquitin-conjugating enzyme E2S
chr8_+_73921061	11.709	NM_003218 NM_017489	TERF1	telomeric repeat binding factor (NIMA-interacting) 1
chr17_+_70117168	11.545		SOX9	SRY (sex determining region Y)-box 9
chr2_+_170662044	11.495		SSB	Sjogren syndrome antigen B (autoantigen La)
chr8_-_101964334	11.370	NM_145690	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr17_+_76183397	11.345	NM_001010982 NM_001145526	AFMID	arylformamidase
chr19_-_55918980	11.338		UBE2S	ubiquitin-conjugating enzyme E2S
chr14_-_64009971	11.307		PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr17_+_70117177	11.291		SOX9	SRY (sex determining region Y)-box 9
chr5_+_137514416	11.151	NM_005733	KIF20A	kinesin family member 20A
chr1_-_68962726	11.133	NM_001114120 NM_017779	DEPDC1	DEP domain containing 1
chr16_-_69760367	11.091		NQO1	NAD(P)H dehydrogenase, quinone 1
chr16_-_69760444	11.030	NM_000903 NM_001025433 NM_001025434	NQO1	NAD(P)H dehydrogenase, quinone 1
chr12_+_79258588	10.943		SYT1	synaptotagmin I
chr11_-_10830452	10.770		EIF4G2	eukaryotic translation initiation factor 4 gamma, 2
chr4_-_176734181	10.738	NM_201591	GPM6A	glycoprotein M6A
chr12_+_49716970	10.726	NM_001100620 NM_005480	TROAP	trophinin associated protein (tastin)
chr5_+_137514753	10.674		KIF20A	kinesin family member 20A
chr8_-_25315791	10.535		KCTD9	potassium channel tetramerisation domain containing 9
chr17_+_45727274	10.533	NM_002265	KPNB1	karyopherin (importin) beta 1
chr15_+_80364902	10.360	NM_001242915 NM_001242916	ZFAND6	zinc finger, AN1-type domain 6
chr1_-_109825767	10.248	NM_001005290 NM_001032291 NM_032636	PSRC1	proline/serine-rich coiled-coil 1
chr7_-_94285477	10.196	NM_001099400 NM_001099401 NM_003919	SGCE	sarcoglycan, epsilon
chr19_+_36606337	10.196		TBCB	tubulin folding cofactor B
chr8_+_26150731	10.063	NM_001177591	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr20_+_30326903	10.058	NM_012112	TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)
chr8_+_42010463	9.947	NM_001134296 NM_006803	AP3M2	adaptor-related protein complex 3, mu 2 subunit
chr14_+_65878579	9.919		FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr1_-_109825683	9.917		PSRC1	proline/serine-rich coiled-coil 1
chr12_-_2986299	9.877	NM_001243088 NM_001243089 NM_021953 NM_202002 NM_202003	FOXM1	forkhead box M1
chr12_-_50419160	9.852	NM_001126103 NM_001126104 NM_013277	RACGAP1	Rac GTPase activating protein 1
chr2_+_63815742	9.840	NM_005917	MDH1	malate dehydrogenase 1, NAD (soluble)
chr7_+_94285676	9.835	NM_001172437 NM_001172438	PEG10	paternally expressed 10
chr2_+_63816092	9.832		MDH1	malate dehydrogenase 1, NAD (soluble)
chr14_-_64010063	9.822	NM_006246	PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr7_-_94285426	9.790		SGCE	sarcoglycan, epsilon
chr15_+_77223942	9.763	NM_002902	RCN2	reticulocalbin 2, EF-hand calcium binding domain
chr2_+_63816143	9.730	NM_001199111 NM_001199112	MDH1	malate dehydrogenase 1, NAD (soluble)
chr11_+_63953630	9.565		STIP1	stress-induced-phosphoprotein 1
chr7_-_94285372	9.534		SGCE	sarcoglycan, epsilon
chr8_+_26435339	9.476	NM_001386	DPYSL2	dihydropyrimidinase-like 2
chrX_+_102631267	9.445	NM_206915 NM_206917	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr17_-_5322870	9.438		NUP88	nucleoporin 88kDa
chr20_+_44441334	9.430		UBE2C	ubiquitin-conjugating enzyme E2C
chr17_-_73150769	9.312	NM_001002032 NM_001002033 NM_016185	HN1	hematological and neurological expressed 1
chr17_+_70117154	9.289	NM_000346	SOX9	SRY (sex determining region Y)-box 9
chr5_-_150138081	9.280	NM_001135644	DCTN4	dynactin 4 (p62)
chr11_+_43702142	9.232	NM_016142	HSD17B12	hydroxysteroid (17-beta) dehydrogenase 12
chr7_+_94285736	9.229		PEG10	paternally expressed 10
chr12_+_27175482	9.220	NM_004264	MED21	mediator complex subunit 21
chr12_-_49582800	9.211	NM_006009	TUBA1A	tubulin, alpha 1a
chr11_-_134093869	9.073		NCAPD3	non-SMC condensin II complex, subunit D3
chr2_-_96874507	8.974		STARD7	StAR-related lipid transfer (START) domain containing 7
chr9_-_35103089	8.972		STOML2	stomatin (EPB72)-like 2
chr5_-_133561745	8.955		PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme
chr5_+_44808967	8.943	NM_016640	MRPS30	mitochondrial ribosomal protein S30
chr17_+_66031814	8.903	NM_002266	KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr19_-_22966972	8.878	NM_001080409	ZNF99	zinc finger protein 99
chr5_+_31532372	8.847	NM_018356	C5orf22	chromosome 5 open reading frame 22
chrX_-_102941582	8.845	NM_001142418 NM_001142423 NM_001142424 NM_001142425 NM_001142426 NM_001142429 NM_001142430 NM_012286	MORF4L2	mortality factor 4 like 2
chr2_-_96873938	8.827		STARD7	StAR-related lipid transfer (START) domain containing 7
chr10_-_58121011	8.802		ZWINT	ZW10 interactor
chr16_-_18812691	8.753	NM_015161	ARL6IP1	ADP-ribosylation factor-like 6 interacting protein 1
chr10_-_58121019	8.735	NM_001005413 NM_007057 NM_032997	ZWINT	ZW10 interactor
chr14_+_52456322	8.714		C14orf166	chromosome 14 open reading frame 166
chr20_+_44441247	8.627	NM_007019 NM_181799 NM_181800 NM_181802 NM_181803	UBE2C	ubiquitin-conjugating enzyme E2C
chrX_+_102631408	8.614		NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr11_-_10830299	8.581		EIF4G2	eukaryotic translation initiation factor 4 gamma, 2
chr5_-_133561551	8.569		PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme
chr6_+_80714321	8.539	NM_001166691 NM_003318	TTK	TTK protein kinase
chr22_+_19467467	8.419		CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr6_-_38670871	8.419		GLO1	glyoxalase I
chr6_-_38670915	8.408		GLO1	glyoxalase I
chr5_+_179132676	8.401		CANX	calnexin
chr17_+_66031885	8.339		KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr7_+_128379452	8.333		CALU	calumenin
chr20_-_48770302	8.333	NM_001162505 NM_199129 NM_199203	TMEM189 TMEM189-UBE2V1	transmembrane protein 189 TMEM189-UBE2V1 readthrough
chr9_-_35103048	8.312		STOML2	stomatin (EPB72)-like 2
chr11_-_134093826	8.292		NCAPD3	non-SMC condensin II complex, subunit D3
chr9_-_95055966	8.274	NM_013417	IARS	isoleucyl-tRNA synthetase
chr1_+_120254418	8.243	NM_006623	PHGDH	phosphoglycerate dehydrogenase
chr9_-_95055986	8.242		IARS	isoleucyl-tRNA synthetase
chr1_+_62902653	8.203		USP1	ubiquitin specific peptidase 1
chr7_+_128379400	8.191		CALU	calumenin
chr4_+_83956238	8.165	NM_016129	COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr1_+_62902735	8.159		USP1	ubiquitin specific peptidase 1
chr9_-_35103144	8.145	NM_013442	STOML2	stomatin (EPB72)-like 2
chr7_+_128379428	8.136		CALU	calumenin
chr11_+_63953586	8.097	NM_006819	STIP1	stress-induced-phosphoprotein 1
chr11_-_119293848	8.085		THY1	Thy-1 cell surface antigen
chr1_+_62902708	8.022		USP1	ubiquitin specific peptidase 1
chr22_+_19467413	8.018	NM_001178010 NM_001178011 NM_003504	CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr17_+_6347733	8.016	NM_001195228 NM_019013	FAM64A	family with sequence similarity 64, member A
chr12_-_2986095	8.004		FOXM1	forkhead box M1
chr9_+_131446105	7.998		SET	SET nuclear oncogene
chr8_-_124408665	7.961		ATAD2	ATPase family, AAA domain containing 2
chr7_+_94285620	7.941	NM_001040152 NM_001184961 NM_001184962 NM_015068	PEG10	paternally expressed 10
chr11_-_10830581	7.939	NM_001042559 NM_001418	EIF4G2	eukaryotic translation initiation factor 4 gamma, 2
chr17_+_34842472	7.907	NM_004773	ZNHIT3	zinc finger, HIT-type containing 3
chr1_-_31769599	7.846	NM_004814	SNRNP40	small nuclear ribonucleoprotein 40kDa (U5)
chr15_-_83876769	7.833		HDGFRP3	hepatoma-derived growth factor, related protein 3
chr20_+_44441671	7.806	NM_181801	UBE2C	ubiquitin-conjugating enzyme E2C
chr6_+_123100645	7.798	NM_001446	FABP7	fatty acid binding protein 7, brain
chr15_-_42749710	7.788	NM_022473	ZFP106	zinc finger protein 106 homolog (mouse)
chr1_-_95392449	7.772		CNN3	calponin 3, acidic
chr11_-_71159442	7.749	NM_001163817 NM_001360	DHCR7	7-dehydrocholesterol reductase
chr9_+_36190885	7.706		CLTA	clathrin, light chain A
chr5_-_137878808	7.675		ETF1	eukaryotic translation termination factor 1
chr1_-_150669499	7.648	NM_018178	GOLPH3L	golgi phosphoprotein 3-like
chr2_-_234763182	7.648	NM_018410	HJURP	Holliday junction recognition protein
chr12_+_6603258	7.636		NCAPD2	non-SMC condensin I complex, subunit D2
chr2_-_234763145	7.634		HJURP	Holliday junction recognition protein
chr7_+_128379395	7.624		CALU	calumenin
chrX_+_119738542	7.531	NM_001137554	MCTS1	malignant T cell amplified sequence 1
chr20_+_47662782	7.527	NM_001316	CSE1L	CSE1 chromosome segregation 1-like (yeast)
chr3_-_145879222	7.510	NM_000935 NM_182943	PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr17_-_40075153	7.493		ACLY	ATP citrate lyase
chr10_+_62538250	7.481		CDK1	cyclin-dependent kinase 1
chr5_-_137090037	7.475	NM_006805	HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr6_-_18264638	7.439	NM_001134709 NM_003472	DEK	DEK oncogene
chr1_+_214776494	7.437	NM_016343	CENPF	centromere protein F, 350/400kDa (mitosin)
chr12_+_6603291	7.421	NM_014865	NCAPD2	non-SMC condensin I complex, subunit D2
chr3_+_50273745	7.421		GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr19_+_36605887	7.420	NM_001281	TBCB	tubulin folding cofactor B
chr6_+_111135823	7.420		AMD1	adenosylmethionine decarboxylase 1
chr9_+_131445933	7.383	NM_001122821	SET	SET nuclear oncogene
chr11_+_63953666	7.355		STIP1	stress-induced-phosphoprotein 1
chr17_-_5322982	7.351	NM_002532	NUP88	nucleoporin 88kDa
chr8_-_124408688	7.344	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chr12_+_56618104	7.312	NM_024068	OBFC2B	oligonucleotide/oligosaccharide-binding fold containing 2B
chr2_-_96874569	7.306	NM_020151	STARD7	StAR-related lipid transfer (START) domain containing 7
chr4_-_174255454	7.272	NM_001130688 NM_002129	HMGB2	high mobility group box 2
chr16_-_81129882	7.269	NM_004483	GCSH	glycine cleavage system protein H (aminomethyl carrier)
chr8_-_124408458	7.265		ATAD2	ATPase family, AAA domain containing 2
chrX_+_119737743	7.261	NM_014060	MCTS1	malignant T cell amplified sequence 1
chr12_+_56618150	7.176		OBFC2B	oligonucleotide/oligosaccharide-binding fold containing 2B
chr5_-_31532164	7.173	NM_001100412 NM_013235	DROSHA	drosha, ribonuclease type III
chr6_+_33359620	7.168		KIFC1	kinesin family member C1
chr8_+_66556887	7.162	NM_001145839 NM_014637	MTFR1	mitochondrial fission regulator 1
chr12_+_79258517	7.155		SYT1	synaptotagmin I
chrX_-_37706816	7.154	NM_006520	DYNLT3	dynein, light chain, Tctex-type 3
chr1_-_33282844	7.118		YARS	tyrosyl-tRNA synthetase
chr6_+_33359604	7.084		KIFC1	kinesin family member C1
chrX_+_48380163	7.071	NM_006579	EBP	emopamil binding protein (sterol isomerase)
chr2_-_47403652	7.053		CALM2	calmodulin 2 (phosphorylase kinase, delta)
chr1_-_33283632	7.031	NM_003680	YARS	tyrosyl-tRNA synthetase
chr17_+_45727558	7.020		KPNB1	karyopherin (importin) beta 1
chrX_-_102319080	6.986		BEX1	brain expressed, X-linked 1
chr5_+_179125977	6.977		CANX	calnexin
chr4_-_76598611	6.963	NM_203504 NM_203505	G3BP2	GTPase activating protein (SH3 domain) binding protein 2
chr14_-_105487413	6.942		CDCA4	cell division cycle associated 4
chr2_+_9346909	6.904		ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr4_+_166248816	6.890	NM_001017369 NM_006745	MSMO1	methylsterol monooxygenase 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.23	4.52e-26	GO:0009987	cellular process
2.31	5.66e-21	GO:0007049	cell cycle
1.62	4.29e-19	GO:0034641	cellular nitrogen compound metabolic process
1.67	4.21e-18	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59	5.36e-18	GO:0006807	nitrogen compound metabolic process
2.53	9.20e-18	GO:0022403	cell cycle phase
2.68	1.30e-17	GO:0000278	mitotic cell cycle
2.37	2.83e-17	GO:0022402	cell cycle process
1.72	6.17e-16	GO:0090304	nucleic acid metabolic process
1.64	2.00e-15	GO:0071842	cellular component organization at cellular level
1.35	2.02e-15	GO:0044237	cellular metabolic process
1.44	9.15e-15	GO:0044260	cellular macromolecule metabolic process
1.60	2.52e-14	GO:0071841	cellular component organization or biogenesis at cellular level
3.48	1.08e-12	GO:0000075	cell cycle checkpoint
3.41	1.44e-12	GO:0071156	regulation of cell cycle arrest
1.49	1.72e-12	GO:0016043	cellular component organization
1.30	5.07e-12	GO:0044238	primary metabolic process
1.47	7.39e-12	GO:0071840	cellular component organization or biogenesis
2.59	1.92e-11	GO:0000279	M phase
1.27	3.90e-11	GO:0008152	metabolic process
1.73	7.21e-11	GO:0006996	organelle organization
2.74	1.03e-10	GO:0010564	regulation of cell cycle process
2.86	1.30e-10	GO:0051325	interphase
2.86	2.00e-10	GO:0051329	interphase of mitotic cell cycle
2.28	2.11e-10	GO:0006259	DNA metabolic process
1.34	1.03e-09	GO:0043170	macromolecule metabolic process
2.06	2.21e-09	GO:0071844	cellular component assembly at cellular level
2.77	2.38e-09	GO:0000087	M phase of mitotic cell cycle
2.51	2.43e-08	GO:0034622	cellular macromolecular complex assembly
1.21	7.23e-08	GO:0065007	biological regulation
2.65	8.23e-08	GO:0000280	nuclear division
2.65	8.23e-08	GO:0007067	mitosis
2.61	9.55e-08	GO:0048285	organelle fission
2.06	2.06e-07	GO:0051726	regulation of cell cycle
1.89	3.00e-07	GO:0033554	cellular response to stress
1.22	4.20e-07	GO:0050789	regulation of biological process
1.22	5.68e-07	GO:0050794	regulation of cellular process
2.13	7.83e-07	GO:0006974	response to DNA damage stimulus
1.75	1.16e-06	GO:0022607	cellular component assembly
2.38	1.38e-06	GO:0051301	cell division
1.56	1.88e-06	GO:0016070	RNA metabolic process
1.99	2.67e-06	GO:0051276	chromosome organization
1.43	4.45e-06	GO:0009058	biosynthetic process
3.18	4.95e-06	GO:0000082	G1/S transition of mitotic cell cycle
1.44	5.99e-06	GO:0044249	cellular biosynthetic process
1.31	6.80e-06	GO:0051716	cellular response to stimulus
2.09	7.79e-06	GO:0034621	cellular macromolecular complex subunit organization
1.65	1.55e-05	GO:0044085	cellular component biogenesis
1.49	3.09e-05	GO:0010467	gene expression
3.35	4.48e-05	GO:0000084	S phase of mitotic cell cycle
2.76	5.51e-05	GO:0006260	DNA replication
3.29	6.82e-05	GO:0051320	S phase
2.23	6.98e-05	GO:0006281	DNA repair
1.51	7.05e-05	GO:0034645	cellular macromolecule biosynthetic process
2.31	7.61e-05	GO:0008380	RNA splicing
1.50	9.71e-05	GO:0009059	macromolecule biosynthetic process
1.82	1.13e-04	GO:0065003	macromolecular complex assembly
1.92	2.44e-04	GO:0016071	mRNA metabolic process
1.55	5.59e-04	GO:0051641	cellular localization
1.59	8.63e-04	GO:0051246	regulation of protein metabolic process
1.30	1.12e-03	GO:0060255	regulation of macromolecule metabolic process
1.57	1.72e-03	GO:0051649	establishment of localization in cell
3.44	2.04e-03	GO:0000216	M/G1 transition of mitotic cell cycle
1.48	2.24e-03	GO:0007399	nervous system development
2.59	3.19e-03	GO:0043623	cellular protein complex assembly
2.42	3.28e-03	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.42	3.28e-03	GO:0000398	nuclear mRNA splicing, via spliceosome
2.81	3.37e-03	GO:0007093	mitotic cell cycle checkpoint
1.98	3.39e-03	GO:0006397	mRNA processing
2.21	3.58e-03	GO:0007017	microtubule-based process
1.26	4.15e-03	GO:0019222	regulation of metabolic process
4.10	4.33e-03	GO:0007051	spindle organization
1.66	4.79e-03	GO:0046907	intracellular transport
1.62	4.93e-03	GO:0045184	establishment of protein localization
2.17	5.45e-03	GO:0007346	regulation of mitotic cell cycle
2.68	5.57e-03	GO:0006310	DNA recombination
1.63	5.71e-03	GO:0043933	macromolecular complex subunit organization
2.36	6.07e-03	GO:0000375	RNA splicing, via transesterification reactions
1.54	7.29e-03	GO:0008104	protein localization
1.33	7.29e-03	GO:0044267	cellular protein metabolic process
1.55	7.48e-03	GO:0042981	regulation of apoptosis
4.36	1.01e-02	GO:0030071	regulation of mitotic metaphase/anaphase transition
1.54	1.11e-02	GO:0043067	regulation of programmed cell death
1.35	1.19e-02	GO:0048523	negative regulation of cellular process
1.60	1.30e-02	GO:0015031	protein transport
3.18	1.32e-02	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.26	1.43e-02	GO:0080090	regulation of primary metabolic process
1.88	1.53e-02	GO:0043086	negative regulation of catalytic activity
1.33	1.62e-02	GO:0048519	negative regulation of biological process
1.70	2.01e-02	GO:0009057	macromolecule catabolic process
1.51	2.25e-02	GO:0010941	regulation of cell death
2.73	2.29e-02	GO:0031570	DNA integrity checkpoint
1.87	2.32e-02	GO:0051247	positive regulation of protein metabolic process
2.44	2.51e-02	GO:0010498	proteasomal protein catabolic process
2.44	2.51e-02	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.75	2.67e-02	GO:0044265	cellular macromolecule catabolic process
2.76	3.02e-02	GO:0000086	G2/M transition of mitotic cell cycle
3.96	3.30e-02	GO:0000819	sister chromatid segregation
2.16	3.31e-02	GO:0051129	negative regulation of cellular component organization
1.74	3.50e-02	GO:0044092	negative regulation of molecular function
1.95	3.99e-02	GO:0033043	regulation of organelle organization
1.66	4.06e-02	GO:0006396	RNA processing
1.44	4.60e-02	GO:0033036	macromolecule localization
1.85	4.76e-02	GO:0006886	intracellular protein transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.23	5.84e-29	GO:0044424	intracellular part
1.22	2.70e-28	GO:0005622	intracellular
1.26	1.32e-24	GO:0043229	intracellular organelle
1.26	2.79e-24	GO:0043226	organelle
1.31	1.02e-23	GO:0005737	cytoplasm
1.29	1.41e-23	GO:0043227	membrane-bounded organelle
1.29	1.75e-23	GO:0043231	intracellular membrane-bounded organelle
1.40	3.97e-19	GO:0005634	nucleus
1.36	5.83e-17	GO:0044444	cytoplasmic part
1.38	1.69e-16	GO:0044446	intracellular organelle part
1.37	3.02e-16	GO:0044422	organelle part
1.68	1.48e-14	GO:0005829	cytosol
1.64	3.88e-13	GO:0044428	nuclear part
1.46	7.96e-13	GO:0032991	macromolecular complex
1.49	9.41e-12	GO:0043234	protein complex
1.55	6.33e-11	GO:0031974	membrane-enclosed lumen
1.60	1.17e-09	GO:0031981	nuclear lumen
1.53	2.00e-09	GO:0070013	intracellular organelle lumen
2.04	3.88e-09	GO:0015630	microtubule cytoskeleton
1.51	5.29e-09	GO:0043233	organelle lumen
1.45	1.39e-08	GO:0043228	non-membrane-bounded organelle
1.45	1.39e-08	GO:0043232	intracellular non-membrane-bounded organelle
1.68	2.59e-08	GO:0005654	nucleoplasm
2.23	3.07e-08	GO:0044427	chromosomal part
2.10	4.68e-08	GO:0005694	chromosome
3.00	1.18e-07	GO:0005819	spindle
1.07	1.77e-07	GO:0005623	cell
1.07	3.14e-07	GO:0044464	cell part
1.55	2.43e-06	GO:0005856	cytoskeleton
1.61	4.58e-05	GO:0044430	cytoskeletal part
2.43	1.33e-04	GO:0000228	nuclear chromosome
2.60	1.51e-04	GO:0044454	nuclear chromosome part
3.50	9.39e-04	GO:0005643	nuclear pore
3.64	1.98e-03	GO:0030496	midbody
2.07	2.02e-03	GO:0005874	microtubule
3.45	2.17e-03	GO:0000922	spindle pole
2.55	2.60e-03	GO:0000775	chromosome, centromeric region
3.05	2.63e-03	GO:0000776	kinetochore
4.47	3.03e-03	GO:0005758	mitochondrial intermembrane space
3.07	4.00e-03	GO:0046930	pore complex
5.96	9.59e-03	GO:0000159	protein phosphatase type 2A complex
4.02	1.02e-02	GO:0031970	organelle envelope lumen
2.05	1.35e-02	GO:0005635	nuclear envelope
2.41	1.53e-02	GO:0000793	condensed chromosome
1.57	2.36e-02	GO:0031967	organelle envelope
7.31	2.60e-02	GO:0005744	mitochondrial inner membrane presequence translocase complex
3.78	4.20e-02	GO:0005876	spindle microtubule
1.54	4.27e-02	GO:0031975	envelope
1.98	4.58e-02	GO:0000785	chromatin

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.39	3.82e-28	GO:0005515	protein binding
1.16	4.72e-15	GO:0005488	binding
1.76	3.65e-05	GO:0019899	enzyme binding
1.69	2.17e-04	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.37	2.23e-04	GO:0000166	nucleotide binding
1.68	2.61e-04	GO:0016817	hydrolase activity, acting on acid anhydrides
1.68	3.39e-04	GO:0016462	pyrophosphatase activity
1.67	8.07e-04	GO:0017111	nucleoside-triphosphatase activity
1.44	9.42e-04	GO:0032559	adenyl ribonucleotide binding
1.45	9.65e-04	GO:0005524	ATP binding
6.70	1.21e-03	GO:0008601	protein phosphatase type 2A regulator activity
1.43	1.30e-03	GO:0030554	adenyl nucleotide binding
1.96	3.19e-03	GO:0016887	ATPase activity
1.37	3.69e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.36	4.50e-03	GO:0032553	ribonucleotide binding
1.36	4.50e-03	GO:0032555	purine ribonucleotide binding
1.36	6.32e-03	GO:0017076	purine nucleotide binding
3.83	2.53e-02	GO:0019888	protein phosphatase regulator activity
1.94	3.28e-02	GO:0042623	ATPase activity, coupled