Motif ID: GLI1..3.p2

Z-value: 1.898


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
GLI1 2735 glioma-associated oncogene homolog 1 (zinc finger protein)
GLI2 2736 GLI-Kruppel family member GLI2
GLI3 2737 GLI-Kruppel family member GLI3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GLI1chr12_+_578539170.561.3e-19Click!
GLI2chr2_+_1215548660.473.3e-13Click!
GLI3chr7_-_422766170.433.9e-11Click!


Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_175792444 27.877 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr12_-_6798419 25.557 ZNF384
zinc finger protein 384
chr12_-_6798619 23.914 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr22_-_19512001 23.526 CLDN5
claudin 5
chr22_-_19511777 20.579 CLDN5
claudin 5
chr22_+_22569155 20.551


chrX_-_106960028 19.076 TSC22D3
TSC22 domain family, member 3
chrX_-_78622711 18.708 ITM2A
integral membrane protein 2A
chr8_+_21916858 17.748 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr16_+_28834407 17.571 NM_007245
NM_145714
NM_148414
NM_148415
NM_148416
ATXN2L




ataxin 2-like




chr8_+_21916685 17.521 NM_001114138
NM_001978
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr12_-_6798528 17.113 NM_133476
ZNF384
zinc finger protein 384
chr15_-_77712436 16.665 NM_024776
PEAK1
NKF3 kinase family member
chr11_-_72380107 16.206 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr10_+_104503724 15.532 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr16_+_28834565 15.386 ATXN2L
ataxin 2-like
chr12_-_45269953 14.662 NELL2
NEL-like 2 (chicken)
chr9_-_113800243 14.205 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chrX_+_13671224 14.070 NM_152634
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr3_-_10067989 13.933 CIDECP
cell death-inducing DFFA-like effector c pseudogene
chr15_+_74421698 13.844 NM_001130136
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr15_+_74421986 13.822 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr19_+_16435632 13.773 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chrX_-_78623006 13.546 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr19_+_45417576 13.241 APOC1
apolipoprotein C-I
chr12_+_79258517 13.237 SYT1
synaptotagmin I
chr19_+_39833096 13.139 SAMD4B
sterile alpha motif domain containing 4B
chr19_+_45418063 13.124 APOC1
apolipoprotein C-I
chr2_-_136875629 13.034 NM_003467
CXCR4
chemokine (C-X-C motif) receptor 4
chr20_-_39766522 12.960


chr11_+_1892098 12.559 NM_001013254
NM_001013255
LSP1

lymphocyte-specific protein 1

chr16_+_30194925 12.500 CORO1A
coronin, actin binding protein, 1A
chr3_-_38071030 12.460 NM_006225
PLCD1
phospholipase C, delta 1
chr19_+_16435734 12.377 KLF2
Kruppel-like factor 2 (lung)
chr3_+_10028579 12.326 LOC442075
uncharacterized LOC442075
chr11_-_64512265 12.294 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr20_+_36149606 12.038 NM_005386
NM_181689
NNAT

neuronatin

chr3_+_49591897 11.857 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr19_+_39833099 11.649 NM_018028
SAMD4B
sterile alpha motif domain containing 4B
chr19_-_33793429 11.623 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr7_-_99680358 11.573 ZNF3
zinc finger protein 3
chr12_-_45270071 11.487 NELL2
NEL-like 2 (chicken)
chr12_-_112819755 11.456 NM_001109662
C12orf51
chromosome 12 open reading frame 51
chr1_+_36689996 11.284 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr4_-_176734181 11.233 NM_201591
GPM6A
glycoprotein M6A
chr4_-_176733901 11.142 GPM6A
glycoprotein M6A
chr5_-_149535138 11.007 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr19_+_33793743 10.998 LOC80054
uncharacterized LOC80054
chr12_-_45270157 10.962 NM_001145108
NM_006159
NELL2

NEL-like 2 (chicken)

chr19_+_3178735 10.950 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr3_+_45067750 10.927 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr7_-_100171269 10.841 NM_001168682
SAP25
Sin3A-associated protein, 25kDa
chr14_+_24584009 10.833 DCAF11
DDB1 and CUL4 associated factor 11
chr6_-_32784727 10.709 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr14_+_92789536 10.567 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr5_+_150400132 10.561 GPX3
glutathione peroxidase 3 (plasma)
chr9_-_86571631 10.550 C9orf64
chromosome 9 open reading frame 64
chr6_-_29600668 10.541 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr5_-_43412417 10.496 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr1_+_36690038 10.444 THRAP3
thyroid hormone receptor associated protein 3
chr22_+_23229959 10.381 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr11_-_64511550 10.191 NM_001098671
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_+_149632772 10.145 NM_004522
KIF5C
kinesin family member 5C
chr3_+_10068123 10.061 FANCD2
Fanconi anemia, complementation group D2
chr13_-_41240607 10.027 NM_002015
FOXO1
forkhead box O1
chr3_-_15468981 9.928 NM_152396
METTL6
methyltransferase like 6
chr14_-_24584125 9.784 NRL
neural retina leucine zipper
chr19_-_3869012 9.743 NM_001145640
NM_015174
ZFR2

zinc finger RNA binding protein 2

chr15_+_42867708 9.687 NM_020759
STARD9
StAR-related lipid transfer (START) domain containing 9
chr11_+_576482 9.669 NM_020901
PHRF1
PHD and ring finger domains 1
chr16_+_28834372 9.650 ATXN2L
ataxin 2-like
chr17_+_7388080 9.596


chr6_-_29600859 9.585 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr22_-_39152008 9.548 NM_001199579
NM_015374
SUN2

Sad1 and UNC84 domain containing 2

chr9_-_86571533 9.484 C9orf64
chromosome 9 open reading frame 64
chr12_+_79258588 9.484 SYT1
synaptotagmin I
chr16_+_30194730 9.465 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr12_-_45270632 9.424 NM_001145107
NELL2
NEL-like 2 (chicken)
chr2_+_203499819 9.406 NM_173511
FAM117B
family with sequence similarity 117, member B
chr6_-_29600959 9.275 NM_001470
NM_021904
GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr20_+_30639981 9.199 NM_001172129
NM_001172130
NM_001172131
NM_001172132
NM_001172133
NM_002110
HCK





hemopoietic cell kinase





chr3_+_10068097 9.152 NM_001018115
NM_033084
FANCD2

Fanconi anemia, complementation group D2

chr1_-_182354649 9.128 GLUL
glutamate-ammonia ligase
chr4_+_166299942 9.047 NM_001873
CPE
carboxypeptidase E
chrX_+_101906293 8.991 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr14_+_24584321 8.893 DCAF11
DDB1 and CUL4 associated factor 11
chr3_+_49449753 8.804 TCTA
T-cell leukemia translocation altered gene
chr6_-_32163299 8.740 NM_022107
GPSM3
G-protein signaling modulator 3
chr14_+_29236882 8.681 FOXG1
forkhead box G1
chr2_+_149633173 8.646


chr21_-_46340776 8.629 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_157002705 8.574


chr15_+_44580870 8.534 NM_138423
NM_177974
CASC4

cancer susceptibility candidate 4

chr14_-_93651242 8.500 NM_022151
MOAP1
modulator of apoptosis 1
chr4_-_176733413 8.490 GPM6A
glycoprotein M6A
chr6_+_72892371 8.406 RIMS1
regulating synaptic membrane exocytosis 1
chr6_-_46703429 8.379 NM_001168357
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr11_-_66084501 8.325 NM_020404
CD248
CD248 molecule, endosialin
chr1_+_101702561 8.304 S1PR1
sphingosine-1-phosphate receptor 1
chr3_-_195306274 8.304 APOD
apolipoprotein D
chr22_+_19710118 8.112 SEPT5-GP1BB
SEPT5-GP1BB readthrough
chr7_-_994008 8.064 ADAP1
ArfGAP with dual PH domains 1
chrX_-_140271275 7.918 LDOC1
leucine zipper, down-regulated in cancer 1
chr7_-_158622184 7.896 ESYT2
extended synaptotagmin-like protein 2
chr1_+_156123321 7.886 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr9_-_86571652 7.829 NM_032307
C9orf64
chromosome 9 open reading frame 64
chrX_-_1655999 7.806 NM_178129
P2RY8
CRLF2
purinergic receptor P2Y, G-protein coupled, 8
cytokine receptor-like factor 2
chrY_-_1605999 7.806 NM_178129
P2RY8
CRLF2
purinergic receptor P2Y, G-protein coupled, 8
cytokine receptor-like factor 2
chr12_-_122018858 7.753 NM_032590
KDM2B
lysine (K)-specific demethylase 2B
chr17_+_48172100 7.702 NM_001199898
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr14_+_24583979 7.700 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr11_+_124609775 7.682 NM_001126181
NM_006176
NRGN

neurogranin (protein kinase C substrate, RC3)

chr19_-_33793441 7.633 CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr7_-_4923246 7.600 NM_018059
RADIL
Ras association and DIL domains
chr11_+_113258512 7.592 NM_178510
ANKK1
ankyrin repeat and kinase domain containing 1
chr17_-_1419770 7.568 INPP5K
inositol polyphosphate-5-phosphatase K
chr14_-_93651182 7.497 MOAP1
modulator of apoptosis 1
chr9_+_123963728 7.436 GSN
gelsolin
chr9_-_98079856 7.383 NM_000136
NM_001243744
FANCC

Fanconi anemia, complementation group C

chr19_+_4969126 7.380 KDM4B
lysine (K)-specific demethylase 4B
chr7_-_108096693 7.372 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr12_-_16757944 7.316 LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_+_24583905 7.255 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr12_+_112204690 7.238 NM_000690
NM_001204889
ALDH2

aldehyde dehydrogenase 2 family (mitochondrial)

chr17_+_7387773 7.233 POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr17_-_1420177 7.230 NM_001135642
NM_016532
NM_130766
INPP5K


inositol polyphosphate-5-phosphatase K


chr22_-_17690778 7.222 NM_017424
CECR1
cat eye syndrome chromosome region, candidate 1
chr19_-_12721493 7.198 NM_020714
ZNF490
zinc finger protein 490
chr1_-_11986455 7.166 NM_138346
KIAA2013
KIAA2013
chr15_+_78632625 7.145 NM_004378
CRABP1
cellular retinoic acid binding protein 1
chr7_+_73624328 7.134 LAT2
linker for activation of T cells family, member 2
chr14_+_100531745 7.122 NM_016337
EVL
Enah/Vasp-like
chr2_+_149632836 7.079 KIF5C
kinesin family member 5C
chr18_-_60987212 6.977 BCL2
B-cell CLL/lymphoma 2
chr11_-_85376061 6.961 CREBZF
CREB/ATF bZIP transcription factor
chr16_+_2588000 6.930 PDPK1
3-phosphoinositide dependent protein kinase-1
chr11_+_124609841 6.863 NRGN
neurogranin (protein kinase C substrate, RC3)
chr7_+_73624347 6.824 LAT2
linker for activation of T cells family, member 2
chr9_-_98079506 6.823 NM_001243743
FANCC
Fanconi anemia, complementation group C
chr20_-_44455932 6.813 NM_003279
TNNC2
troponin C type 2 (fast)
chr17_+_42219235 6.802 NM_001171251
NM_024032
C17orf53

chromosome 17 open reading frame 53

chr3_-_12200850 6.775 NM_003256
TIMP4
TIMP metallopeptidase inhibitor 4
chr16_+_27325269 6.762 IL4R
interleukin 4 receptor
chr19_-_46318432 6.729 NM_030785
RSPH6A
radial spoke head 6 homolog A (Chlamydomonas)
chr7_-_994259 6.729 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chrX_-_140271293 6.727 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr7_-_158622202 6.726 NM_020728
ESYT2
extended synaptotagmin-like protein 2
chr19_+_39833132 6.723 SAMD4B
sterile alpha motif domain containing 4B
chr19_-_39108534 6.667 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr19_-_49140569 6.654 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr11_-_119252267 6.641 USP2
ubiquitin specific peptidase 2
chr5_-_168727715 6.622 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr9_-_100881515 6.567 TRIM14
tripartite motif containing 14
chr10_-_105212022 6.465 CALHM2
calcium homeostasis modulator 2
chr19_+_56652529 6.443 NM_001253792
NM_018337
ZNF444

zinc finger protein 444

chr16_+_27325244 6.441 NM_000418
NM_001008699
IL4R

interleukin 4 receptor

chr21_-_46340821 6.438 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_95297424 6.419 ELL2
elongation factor, RNA polymerase II, 2
chr2_-_9695827 6.399 ADAM17
ADAM metallopeptidase domain 17
chr17_+_42219382 6.379 C17orf53
chromosome 17 open reading frame 53
chr4_+_72052354 6.292 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr19_+_4969123 6.284 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr6_-_133084585 6.183 NM_078488
VNN2
vanin 2
chr1_-_40105296 6.158 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr19_-_16653202 6.153 CHERP
calcium homeostasis endoplasmic reticulum protein
chr10_+_47746919 6.147 NM_001630
ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chr5_-_95297597 6.114 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr1_-_38512446 6.104 NM_002699
POU3F1
POU class 3 homeobox 1
chr1_-_182573393 6.075 NM_002928
RGS16
regulator of G-protein signaling 16
chr8_+_23104120 6.053 CHMP7
charged multivesicular body protein 7
chr17_+_42219300 6.053 C17orf53
chromosome 17 open reading frame 53
chr17_+_7531275 6.009 SHBG
sex hormone-binding globulin
chr17_-_39743085 5.987 NM_000526
KRT14
keratin 14
chr3_+_4535160 5.980 ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr19_-_40919270 5.968 NM_020956
NM_181882
PRX

periaxin

chr16_-_31483425 5.945


chr16_-_3109335 5.943 LOC100507419
uncharacterized LOC100507419
chr19_-_58874078 5.929 NM_001207009
NM_198458
ZNF497

zinc finger protein 497

chr22_-_18484183 5.903 MICAL3
microtubule associated monoxygenase, calponin and LIM domain containing 3
chr17_+_26850958 5.902 NM_003593
FOXN1
forkhead box N1
chr10_+_8096772 5.902 GATA3
GATA binding protein 3
chr12_+_10365415 5.900 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr19_+_10541334 5.875 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr11_+_117049838 5.871 NM_001040455
SIDT2
SID1 transmembrane family, member 2
chr3_+_16926451 5.854 NM_001144382
PLCL2
phospholipase C-like 2
chr19_-_49176263 5.811 NM_145807
NTN5
netrin 5
chr20_-_49253425 5.810 NM_080829
FAM65C
family with sequence similarity 65, member C
chr8_+_27183047 5.808 PTK2B
PTK2B protein tyrosine kinase 2 beta
chr19_-_41859767 5.805 TGFB1
transforming growth factor, beta 1
chr3_-_179169330 5.803 NM_021629
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr12_-_53448167 5.801 LOC283335
uncharacterized LOC283335
chr10_+_8097350 5.781 GATA3
GATA binding protein 3
chr8_-_101322180 5.769 RNF19A
ring finger protein 19A
chr16_+_2587951 5.755 NM_002613
NM_031268
PDPK1

3-phosphoinositide dependent protein kinase-1

chr1_-_157108169 5.754 NM_005240
NM_001145312
ETV3

ets variant 3

chr7_-_150498362 5.707 NM_014020
TMEM176B
transmembrane protein 176B
chr19_+_37407230 5.703 NM_001204835
NM_001204836
NM_001204837
NM_001204838
NM_001204839
NM_198539
ZNF568





zinc finger protein 568





chr7_+_73624086 5.696 NM_014146
NM_032463
NM_032464
LAT2


linker for activation of T cells family, member 2


chr5_+_161275541 5.691 NM_001127645
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr12_-_53613883 5.680 RARG
retinoic acid receptor, gamma

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.25 3.21e-22 GO:0065007 biological regulation
1.25 5.53e-19 GO:0050789 regulation of biological process
1.25 1.28e-17 GO:0050794 regulation of cellular process
1.37 2.51e-15 GO:0032502 developmental process
1.42 7.50e-15 GO:0048856 anatomical structure development
1.43 1.59e-13 GO:0048731 system development
1.38 1.60e-13 GO:0007275 multicellular organismal development
1.35 1.16e-12 GO:0023052 signaling
1.53 2.22e-12 GO:0048583 regulation of response to stimulus
1.57 4.32e-11 GO:0009653 anatomical structure morphogenesis
1.23 4.49e-11 GO:0050896 response to stimulus
1.12 7.97e-11 GO:0009987 cellular process
1.24 1.95e-09 GO:0032501 multicellular organismal process
1.37 3.16e-09 GO:0048518 positive regulation of biological process
1.41 4.78e-09 GO:0042221 response to chemical stimulus
1.49 7.17e-09 GO:0023051 regulation of signaling
1.42 8.58e-09 GO:0048869 cellular developmental process
1.27 1.47e-08 GO:0051716 cellular response to stimulus
1.65 1.68e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.31 2.14e-08 GO:0007165 signal transduction
1.27 3.95e-08 GO:0019222 regulation of metabolic process
1.29 5.07e-08 GO:0031323 regulation of cellular metabolic process
1.43 6.86e-08 GO:0048513 organ development
1.77 8.48e-08 GO:0010628 positive regulation of gene expression
1.50 1.25e-07 GO:0009966 regulation of signal transduction
1.49 1.26e-07 GO:0007399 nervous system development
1.40 1.37e-07 GO:0030154 cell differentiation
1.29 1.70e-07 GO:0080090 regulation of primary metabolic process
1.60 3.49e-07 GO:0009605 response to external stimulus
1.38 3.90e-07 GO:0006355 regulation of transcription, DNA-dependent
1.88 7.37e-07 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.76 1.03e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.33 1.12e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 1.34e-06 GO:0060255 regulation of macromolecule metabolic process
1.33 1.77e-06 GO:0010468 regulation of gene expression
1.34 2.22e-06 GO:0048522 positive regulation of cellular process
1.90 2.42e-06 GO:0032583 regulation of gene-specific transcription
1.32 2.48e-06 GO:0031326 regulation of cellular biosynthetic process
1.54 2.67e-06 GO:0010646 regulation of cell communication
1.35 2.71e-06 GO:0051252 regulation of RNA metabolic process
1.31 3.20e-06 GO:0009889 regulation of biosynthetic process
1.31 5.10e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.48 6.11e-06 GO:0051239 regulation of multicellular organismal process
1.67 7.56e-06 GO:0002682 regulation of immune system process
1.71 1.50e-05 GO:0009887 organ morphogenesis
1.32 1.88e-05 GO:0006950 response to stress
1.32 1.92e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.66 2.20e-05 GO:0051254 positive regulation of RNA metabolic process
1.55 2.56e-05 GO:0050793 regulation of developmental process
1.31 2.67e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.76 3.09e-05 GO:0006935 chemotaxis
1.76 3.09e-05 GO:0042330 taxis
1.33 4.18e-05 GO:0065008 regulation of biological quality
1.94 5.52e-05 GO:0045597 positive regulation of cell differentiation
1.31 5.67e-05 GO:0048519 negative regulation of biological process
1.33 7.42e-05 GO:0048523 negative regulation of cellular process
1.54 7.69e-05 GO:0009611 response to wounding
1.55 9.24e-05 GO:0040011 locomotion
1.87 9.97e-05 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.78 1.01e-04 GO:0051094 positive regulation of developmental process
2.14 1.73e-04 GO:0043193 positive regulation of gene-specific transcription
1.79 2.27e-04 GO:0007409 axonogenesis
1.43 3.03e-04 GO:0002376 immune system process
1.56 3.22e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.55 3.52e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.57 3.60e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.53 4.87e-04 GO:0048584 positive regulation of response to stimulus
1.74 5.63e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.33 8.20e-04 GO:0007166 cell surface receptor linked signaling pathway
1.91 9.18e-04 GO:0051270 regulation of cellular component movement
1.40 1.04e-03 GO:0009893 positive regulation of metabolic process
1.67 1.13e-03 GO:0048858 cell projection morphogenesis
1.53 1.17e-03 GO:0007267 cell-cell signaling
1.84 1.21e-03 GO:0007411 axon guidance
1.71 1.23e-03 GO:0048812 neuron projection morphogenesis
1.42 1.49e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.66 1.70e-03 GO:0032990 cell part morphogenesis
1.45 1.77e-03 GO:0007154 cell communication
1.89 1.81e-03 GO:0040012 regulation of locomotion
1.67 1.85e-03 GO:0031175 neuron projection development
1.60 1.90e-03 GO:0000902 cell morphogenesis
1.69 2.33e-03 GO:0050776 regulation of immune response
1.45 2.63e-03 GO:0032879 regulation of localization
1.52 3.13e-03 GO:2000026 regulation of multicellular organismal development
1.65 3.51e-03 GO:0019226 transmission of nerve impulse
1.65 3.51e-03 GO:0035637 multicellular organismal signaling
1.52 3.81e-03 GO:0006468 protein phosphorylation
1.48 4.00e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.53 4.26e-03 GO:0030182 neuron differentiation
1.56 4.29e-03 GO:0032989 cellular component morphogenesis
1.63 5.70e-03 GO:0000904 cell morphogenesis involved in differentiation
1.37 5.88e-03 GO:0010033 response to organic substance
1.47 6.26e-03 GO:0009891 positive regulation of biosynthetic process
1.46 6.41e-03 GO:0006351 transcription, DNA-dependent
1.88 6.75e-03 GO:0030334 regulation of cell migration
2.15 6.83e-03 GO:0040017 positive regulation of locomotion
1.62 6.89e-03 GO:0048585 negative regulation of response to stimulus
1.54 8.42e-03 GO:0030030 cell projection organization
1.86 1.01e-02 GO:2000145 regulation of cell motility
1.57 1.08e-02 GO:0048666 neuron development
1.65 1.09e-02 GO:0002684 positive regulation of immune system process
1.60 1.21e-02 GO:0007417 central nervous system development
1.43 1.30e-02 GO:0048468 cell development
1.33 1.32e-02 GO:0065009 regulation of molecular function
1.55 1.36e-02 GO:0042060 wound healing
2.10 1.37e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.37 1.47e-02 GO:0031325 positive regulation of cellular metabolic process
1.64 1.60e-02 GO:0007268 synaptic transmission
2.09 1.62e-02 GO:0051272 positive regulation of cellular component movement
1.57 1.77e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.49 1.94e-02 GO:0019220 regulation of phosphate metabolic process
1.49 1.94e-02 GO:0051174 regulation of phosphorus metabolic process
2.11 1.98e-02 GO:0030335 positive regulation of cell migration
2.11 1.98e-02 GO:2000147 positive regulation of cell motility
1.50 1.99e-02 GO:0009719 response to endogenous stimulus
1.42 2.06e-02 GO:0022008 neurogenesis
1.44 2.32e-02 GO:0048699 generation of neurons
2.53 2.33e-02 GO:0045637 regulation of myeloid cell differentiation
1.56 2.37e-02 GO:0051253 negative regulation of RNA metabolic process
1.57 2.94e-02 GO:0080134 regulation of response to stress
1.52 3.08e-02 GO:0010629 negative regulation of gene expression
1.49 3.14e-02 GO:0045595 regulation of cell differentiation
1.74 3.18e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.64 4.30e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.57 4.33e-02 GO:0007596 blood coagulation
1.57 4.33e-02 GO:0050817 coagulation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.37 6.98e-08 GO:0044459 plasma membrane part
1.44 6.51e-05 GO:0000267 cell fraction
1.41 7.35e-05 GO:0005887 integral to plasma membrane
1.40 1.21e-04 GO:0031226 intrinsic to plasma membrane
1.43 3.60e-03 GO:0005626 insoluble fraction
1.43 4.36e-03 GO:0005624 membrane fraction
1.61 1.19e-02 GO:0009986 cell surface

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 2.23e-12 GO:0005488 binding
1.19 4.85e-12 GO:0005515 protein binding
1.74 2.98e-08 GO:0043565 sequence-specific DNA binding
1.58 1.27e-07 GO:0001071 nucleic acid binding transcription factor activity
1.58 1.27e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.55 5.28e-07 GO:0030528 transcription regulator activity
1.96 6.02e-06 GO:0016563 transcription activator activity
1.94 1.74e-04 GO:0032403 protein complex binding
1.85 4.63e-04 GO:0008134 transcription factor binding
1.42 8.42e-04 GO:0005102 receptor binding
1.26 1.57e-03 GO:0003677 DNA binding
1.74 8.10e-03 GO:0005083 small GTPase regulator activity
1.92 8.16e-03 GO:0010843 promoter binding
1.89 1.09e-02 GO:0000975 regulatory region DNA binding
1.89 1.09e-02 GO:0001067 regulatory region nucleic acid binding
1.89 1.09e-02 GO:0044212 transcription regulatory region DNA binding
1.76 1.26e-02 GO:0005261 cation channel activity
1.55 2.24e-02 GO:0030695 GTPase regulator activity
1.53 3.47e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.36 4.55e-02 GO:0030234 enzyme regulator activity