Motif ID: GTF2I.p2

Z-value: 3.178


Transcription factors associated with GTF2I.p2:

Gene SymbolEntrez IDGene Name
GTF2I 2969 general transcription factor II, i

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2Ichr7_+_74072038-0.111.2e-01Click!


Activity profile for motif GTF2I.p2.

activity profile for motif GTF2I.p2


Sorted Z-values histogram for motif GTF2I.p2

Sorted Z-values for motif GTF2I.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_29600668 56.935 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr16_-_30934437 56.364 FBXL19-AS1
FBXL19 antisense RNA 1 (non-protein coding)
chr1_-_20812727 54.164 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_-_49149252 51.608 NM_001217
CA11
carbonic anhydrase XI
chr12_-_6798419 46.792 ZNF384
zinc finger protein 384
chr4_-_16900348 44.774 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr12_-_45270071 43.402 NELL2
NEL-like 2 (chicken)
chr12_-_45270157 43.216 NM_001145108
NM_006159
NELL2

NEL-like 2 (chicken)

chr4_-_16900256 41.959 LDB2
LIM domain binding 2
chr6_-_29600859 39.931 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr12_+_6930689 39.041 NM_014449
NM_019858
GPR162

G protein-coupled receptor 162

chr11_+_17757494 38.466 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr4_-_16900028 37.724 LDB2
LIM domain binding 2
chr6_-_29600959 36.800 NM_001470
NM_021904
GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr12_-_45269953 34.878 NELL2
NEL-like 2 (chicken)
chr7_+_64498643 33.959 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr3_-_42307661 33.776 NM_000729
CCK
cholecystokinin
chr12_-_45270632 32.683 NM_001145107
NELL2
NEL-like 2 (chicken)
chr4_-_5890142 31.750 CRMP1
collapsin response mediator protein 1
chr5_+_17217474 31.715 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr2_+_79740059 31.438 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr11_-_64410785 31.268 NM_138734
NRXN2
neurexin 2
chr9_+_130374466 31.007 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr21_-_45759077 30.331 C21orf2
chromosome 21 open reading frame 2
chr3_-_9439122 30.204 LOC440944
uncharacterized LOC440944
chr1_+_151254740 29.949 NM_020832
ZNF687
zinc finger protein 687
chr3_+_11034436 29.639 SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr12_-_16759939 29.590 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr17_-_7120917 29.469 NM_001128827
DLG4
discs, large homolog 4 (Drosophila)
chr19_-_47975074 29.110 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr5_+_17217781 28.990 BASP1
brain abundant, membrane attached signal protein 1
chrX_-_153362979 27.961 MECP2
LOC728653
methyl CpG binding protein 2 (Rett syndrome)
uncharacterized LOC728653
chr11_-_118661826 27.787 DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr7_-_129251465 27.580


chr2_+_45169036 27.003 NM_005413
SIX3
SIX homeobox 3
chrX_-_70288155 26.878 NM_013346
SNX12
sorting nexin 12
chr1_+_154193294 26.341 NM_014847
UBAP2L
ubiquitin associated protein 2-like
chr10_-_61469322 26.069 NM_194298
LOC100129721
SLC16A9
uncharacterized LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr3_+_167453431 25.413 NM_001122752
NM_005025
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr12_-_16759733 25.115 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_-_10547340 23.759 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr12_-_6798619 23.657 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr7_+_86273867 23.534 GRM3
glutamate receptor, metabotropic 3
chr13_-_36705432 22.994 DCLK1
doublecortin-like kinase 1
chr16_-_4323000 22.992 NM_003223
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr6_+_7108864 22.966 RREB1
ras responsive element binding protein 1
chr16_-_4322695 22.784 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr11_-_118661856 22.589 DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr6_-_29595934 22.532 NM_021903
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr16_+_89213915 22.479


chr12_-_6798528 22.455 NM_133476
ZNF384
zinc finger protein 384
chr15_-_88799961 21.980 NM_001007156
NM_001012338
NM_001243101
NM_002530
NTRK3



neurotrophic tyrosine kinase, receptor, type 3



chr19_+_35629727 21.877 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr8_+_28747885 21.805 NM_001135726
HMBOX1
homeobox containing 1
chr4_-_5890266 21.314 NM_001313
CRMP1
collapsin response mediator protein 1
chr19_-_47975244 21.114 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr17_-_58469446 21.075 USP32
ubiquitin specific peptidase 32
chr1_+_55464605 20.922 NM_057176
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr19_+_56652529 20.874 NM_001253792
NM_018337
ZNF444

zinc finger protein 444

chr17_+_40834571 20.584 NM_003632
CNTNAP1
contactin associated protein 1
chr13_-_45150601 20.555 NM_001243799
NM_183422
TSC22D1

TSC22 domain family, member 1

chr20_+_44657858 20.258 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr16_+_28834407 20.220 NM_007245
NM_145714
NM_148414
NM_148415
NM_148416
ATXN2L




ataxin 2-like




chr11_-_64490654 20.163 NM_015080
NM_138732
NRXN2

neurexin 2

chr11_-_118661855 19.622 DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr7_+_21468293 19.585


chr1_-_154193044 19.399 C1orf43
chromosome 1 open reading frame 43
chr16_+_28834565 19.267 ATXN2L
ataxin 2-like
chr12_+_54332575 19.236 NM_017410
HOXC13
homeobox C13
chr11_-_118661898 19.230 NM_004397
DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr8_-_38034168 19.122 LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_+_69064316 19.107 AUTS2
autism susceptibility candidate 2
chr16_+_222845 19.070 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr12_-_16758839 19.018 NM_001243612
LMO3
LIM domain only 3 (rhombotin-like 2)
chr19_-_42498221 18.937 ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr1_-_155532322 18.824 NM_018489
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr18_+_43405544 18.770 NM_213602
SIGLEC15
sialic acid binding Ig-like lectin 15
chr20_-_3154169 18.716 ProSAPiP1
ProSAPiP1 protein
chr8_-_26371387 18.709 NM_007257
PNMA2
paraneoplastic antigen MA2
chr11_-_2160199 18.709 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chrX_+_103031753 18.662 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr1_-_27930360 18.435 AHDC1
AT hook, DNA binding motif, containing 1
chr19_+_35521591 18.406 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr2_-_218843541 18.373 TNS1
tensin 1
chr12_-_106533810 18.370 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr14_+_29236882 18.340 FOXG1
forkhead box G1
chr2_+_230787195 18.229 NM_174899
FBXO36
F-box protein 36
chr8_-_33457435 18.133 NM_024025
DUSP26
dual specificity phosphatase 26 (putative)
chr1_+_110753910 17.888 KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr8_-_110657025 17.841 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr13_-_67804432 17.632 NM_020403
NM_203487
PCDH9

protocadherin 9

chrX_+_49644469 17.534 NM_001145073
USP27X
ubiquitin specific peptidase 27, X-linked
chr16_+_56225301 17.505 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr17_-_40913274 17.418 LOC100190938
uncharacterized LOC100190938
chrX_-_137793826 17.333 NM_004114
FGF13
fibroblast growth factor 13
chr6_-_29595746 17.320 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr15_-_37392358 17.306 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr1_-_183387501 17.164 NM_015039
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr20_-_62130390 17.158 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr14_-_21945031 17.129 NM_032846
RAB2B
RAB2B, member RAS oncogene family
chr16_+_28834360 17.069 ATXN2L
ataxin 2-like
chr11_+_125034604 17.059 PKNOX2
PBX/knotted 1 homeobox 2
chr15_+_43809805 17.058 NM_002373
MAP1A
microtubule-associated protein 1A
chr1_-_11714396 17.038 FBXO2
F-box protein 2
chr11_+_73359734 16.892 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr7_+_73442486 16.765 ELN
elastin
chr13_+_58205943 16.748 PCDH17
protocadherin 17
chr1_-_156470538 16.662 MEF2D
myocyte enhancer factor 2D
chr8_+_104512975 16.632 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr1_-_177133818 16.594 ASTN1
astrotactin 1
chr10_+_104678001 16.588 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chrX_-_137793394 16.544 FGF13
fibroblast growth factor 13
chr12_-_16759430 16.314 LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_+_29234325 16.280 CHN2
chimerin (chimaerin) 2
chr18_+_46065367 16.150 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr6_-_46459010 16.115 NM_001251974
RCAN2
regulator of calcineurin 2
chr7_+_29234111 15.903 NM_004067
CHN2
chimerin (chimaerin) 2
chr5_+_140345746 15.887 NM_018899
PCDHAC2
protocadherin alpha subfamily C, 2
chr2_+_39664544 15.742 LOC728730
uncharacterized LOC728730
chr17_+_64960754 15.724 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr19_+_54926604 15.651 NM_001005367
NM_001201461
NM_020659
TTYH1


tweety homolog 1 (Drosophila)


chr20_+_10199455 15.574 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr14_-_76448091 15.543 NM_003239
TGFB3
transforming growth factor, beta 3
chr8_-_144241918 15.506 NM_001130478
LY6H
lymphocyte antigen 6 complex, locus H
chr14_-_23822025 15.460 NM_016609
SLC22A17
solute carrier family 22, member 17
chr7_+_30951414 15.456 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr12_-_49365545 15.430 NM_003394
WNT10B
wingless-type MMTV integration site family, member 10B
chr17_+_29421956 15.258 NF1
neurofibromin 1
chr19_+_56652689 15.189 ZNF444
zinc finger protein 444
chr16_-_10276610 15.122 NM_000833
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr5_-_149535138 15.074 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr16_+_28834372 15.023 ATXN2L
ataxin 2-like
chr16_-_65155984 14.777 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_-_154155594 14.729 TPM3
tropomyosin 3
chr19_-_6279797 14.689


chr11_-_130184314 14.683 ZBTB44
zinc finger and BTB domain containing 44
chr1_-_156399183 14.679 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr17_+_36861398 14.650 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr17_-_40913028 14.649 LOC100190938
uncharacterized LOC100190938
chr8_-_22549901 14.627 NM_001199880
EGR3
early growth response 3
chr19_-_42498320 14.614 NM_152296
ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr3_+_11034419 14.537 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr14_-_60337350 14.532 NM_021136
RTN1
reticulon 1
chr2_+_79740171 14.509 CTNNA2
catenin (cadherin-associated protein), alpha 2
chr11_-_2159784 14.484 IGF2
insulin-like growth factor 2 (somatomedin A)
chr16_+_55542909 14.437 NM_017839
LPCAT2
lysophosphatidylcholine acyltransferase 2
chr19_+_45754551 14.401 MARK4
MAP/microtubule affinity-regulating kinase 4
chr12_+_49209300 14.379 NM_001206916
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr7_+_73442451 14.353 ELN
elastin
chr1_-_223537400 14.297 NM_001037175
NM_017982
SUSD4

sushi domain containing 4

chr9_+_35538890 14.294 RUSC2
RUN and SH3 domain containing 2
chr17_-_27278324 14.289 PHF12
PHD finger protein 12
chr14_-_81687265 14.212 NM_015859
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr16_-_65155965 14.207 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr11_-_72385411 14.195 NM_002599
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr6_-_33285493 14.194 NM_005453
ZBTB22
zinc finger and BTB domain containing 22
chr7_-_150974179 14.141 NM_003078
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr14_+_24837225 14.095 NM_001198965
NM_004554
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chrX_-_54384436 14.072 NM_001002838
NM_020922
WNK3

WNK lysine deficient protein kinase 3

chr6_-_6007632 14.039 NM_016588
NRN1
neuritin 1
chr7_+_94024201 14.022 COL1A2
collagen, type I, alpha 2
chr17_+_29718777 13.986 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr1_+_169075869 13.957 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr12_-_57914287 13.902 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr5_+_172483285 13.879 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr16_+_226678 13.772 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr1_+_244998967 13.727 FAM36A
family with sequence similarity 36, member A
chr8_-_33457279 13.703 DUSP26
dual specificity phosphatase 26 (putative)
chrX_+_70315637 13.674 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr19_-_49339913 13.667 NM_016246
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr7_+_97910978 13.661 NM_001159491
NM_015379
BRI3

brain protein I3

chr5_-_133706717 13.636 CDKL3
cyclin-dependent kinase-like 3
chr1_-_68697997 13.592 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr7_+_73442426 13.551 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chrX_+_152760452 13.528 BGN
biglycan
chr6_-_31514620 13.504 NM_001204078
NM_130463
NM_138282
ATP6V1G2


ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2


chr20_-_55841090 13.487 BMP7
bone morphogenetic protein 7
chr1_+_164528586 13.466 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr9_+_35538628 13.448 NM_001135999
RUSC2
RUN and SH3 domain containing 2
chr1_+_183605207 13.415 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr8_+_80523339 13.408 STMN2
stathmin-like 2
chr3_-_133614421 13.369 NM_016577
RAB6B
RAB6B, member RAS oncogene family
chr7_-_140624280 13.367 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr19_-_51472003 13.334 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr7_+_21467572 13.333 NM_003112
SP4
Sp4 transcription factor
chr17_+_40913233 13.278 RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr5_-_149535309 13.251 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr8_+_80523376 13.241 STMN2
stathmin-like 2
chr19_+_40973049 13.200 NM_020971
SPTBN4
spectrin, beta, non-erythrocytic 4
chr19_+_49622480 13.076 NM_003660
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr10_-_32636134 13.001 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr1_-_155145732 12.975 NM_173852
KRTCAP2
keratinocyte associated protein 2
chr13_+_58205788 12.942 NM_001040429
PCDH17
protocadherin 17
chr2_+_220492286 12.916 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr20_-_48099178 12.899 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr22_+_41777932 12.862 NM_003216
TEF
thyrotrophic embryonic factor
chr11_-_31832592 12.840 PAX6
paired box 6
chr5_+_71403040 12.831 NM_005909
MAP1B
microtubule-associated protein 1B
chr7_+_86274076 12.829 GRM3
glutamate receptor, metabotropic 3
chr11_-_31832758 12.721 PAX6
paired box 6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.26 3.37e-59 GO:0065007 biological regulation
1.27 1.80e-54 GO:0050789 regulation of biological process
1.28 2.28e-54 GO:0050794 regulation of cellular process
1.16 3.43e-54 GO:0009987 cellular process
1.42 1.55e-50 GO:0023052 signaling
1.50 6.74e-49 GO:0048731 system development
1.45 6.58e-45 GO:0048856 anatomical structure development
1.40 1.02e-44 GO:0032502 developmental process
1.42 1.93e-44 GO:0007275 multicellular organismal development
1.68 1.17e-42 GO:0007399 nervous system development
1.38 5.74e-35 GO:0007165 signal transduction
1.58 1.01e-31 GO:0009653 anatomical structure morphogenesis
1.31 2.18e-31 GO:0051716 cellular response to stimulus
1.76 1.09e-30 GO:0022008 neurogenesis
1.40 1.50e-29 GO:0048518 positive regulation of biological process
1.26 2.28e-29 GO:0032501 multicellular organismal process
1.76 4.01e-29 GO:0048699 generation of neurons
1.81 7.27e-29 GO:0007267 cell-cell signaling
1.46 1.26e-25 GO:0048513 organ development
1.79 3.32e-25 GO:0030182 neuron differentiation
1.64 7.67e-25 GO:0007154 cell communication
1.56 2.13e-24 GO:0051239 regulation of multicellular organismal process
1.39 4.49e-24 GO:0048522 positive regulation of cellular process
1.43 7.21e-24 GO:0030154 cell differentiation
1.42 8.52e-24 GO:0048869 cellular developmental process
1.38 6.01e-23 GO:0048519 negative regulation of biological process
1.89 5.36e-22 GO:0019226 transmission of nerve impulse
1.89 5.36e-22 GO:0035637 multicellular organismal signaling
1.38 2.32e-20 GO:0048523 negative regulation of cellular process
1.91 4.88e-20 GO:0007268 synaptic transmission
1.19 5.07e-20 GO:0050896 response to stimulus
1.58 1.83e-19 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.28 4.20e-19 GO:0080090 regulation of primary metabolic process
1.58 4.76e-19 GO:0032879 regulation of localization
1.83 4.81e-19 GO:0000904 cell morphogenesis involved in differentiation
1.27 4.86e-19 GO:0031323 regulation of cellular metabolic process
1.25 2.05e-18 GO:0019222 regulation of metabolic process
1.81 2.71e-18 GO:0007417 central nervous system development
1.76 2.92e-18 GO:0048666 neuron development
1.59 3.35e-18 GO:0050793 regulation of developmental process
1.58 4.03e-18 GO:0048468 cell development
1.65 4.37e-18 GO:2000026 regulation of multicellular organismal development
1.86 4.93e-18 GO:0048812 neuron projection morphogenesis
1.32 7.56e-18 GO:0031326 regulation of cellular biosynthetic process
1.36 7.56e-18 GO:0065008 regulation of biological quality
1.40 8.78e-18 GO:0007166 cell surface receptor linked signaling pathway
1.68 1.04e-17 GO:0010628 positive regulation of gene expression
1.73 1.46e-17 GO:0000902 cell morphogenesis
1.31 1.69e-17 GO:0009889 regulation of biosynthetic process
1.80 2.76e-17 GO:0031175 neuron projection development
1.84 5.91e-17 GO:0048667 cell morphogenesis involved in neuron differentiation
1.86 6.11e-17 GO:0007409 axonogenesis
1.69 6.73e-17 GO:0032989 cellular component morphogenesis
1.34 9.10e-17 GO:0042221 response to chemical stimulus
1.77 1.42e-16 GO:0048858 cell projection morphogenesis
1.26 3.15e-16 GO:0016043 cellular component organization
1.30 4.43e-16 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.76 4.95e-16 GO:0032990 cell part morphogenesis
1.26 5.31e-16 GO:0051179 localization
1.89 9.79e-16 GO:0007420 brain development
1.29 9.84e-16 GO:0051171 regulation of nitrogen compound metabolic process
1.30 2.40e-15 GO:0010468 regulation of gene expression
1.66 2.99e-15 GO:0030030 cell projection organization
1.67 1.16e-14 GO:0009887 organ morphogenesis
1.25 1.54e-14 GO:0060255 regulation of macromolecule metabolic process
1.44 2.25e-14 GO:0009893 positive regulation of metabolic process
1.57 2.95e-14 GO:0051173 positive regulation of nitrogen compound metabolic process
1.30 3.64e-14 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.63 4.99e-14 GO:0007167 enzyme linked receptor protein signaling pathway
1.38 7.59e-14 GO:0023051 regulation of signaling
1.53 9.02e-14 GO:0040011 locomotion
1.32 1.08e-13 GO:0006355 regulation of transcription, DNA-dependent
1.29 1.11e-13 GO:0010556 regulation of macromolecule biosynthetic process
1.24 1.40e-13 GO:0071840 cellular component organization or biogenesis
1.57 1.44e-13 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 1.78e-13 GO:0010604 positive regulation of macromolecule metabolic process
1.63 1.96e-13 GO:0045893 positive regulation of transcription, DNA-dependent
1.34 4.36e-13 GO:0048583 regulation of response to stimulus
1.30 5.91e-13 GO:0051252 regulation of RNA metabolic process
1.43 6.13e-13 GO:0031325 positive regulation of cellular metabolic process
1.73 9.01e-13 GO:0051094 positive regulation of developmental process
1.58 1.33e-12 GO:0045595 regulation of cell differentiation
1.87 1.82e-12 GO:0022603 regulation of anatomical structure morphogenesis
1.58 2.31e-12 GO:0051254 positive regulation of RNA metabolic process
1.50 3.00e-12 GO:0006351 transcription, DNA-dependent
1.51 3.72e-12 GO:0031328 positive regulation of cellular biosynthetic process
1.33 6.33e-12 GO:0006464 protein modification process
1.55 7.64e-12 GO:0051049 regulation of transport
1.50 1.38e-11 GO:0009891 positive regulation of biosynthetic process
1.46 1.47e-11 GO:0042127 regulation of cell proliferation
1.83 1.59e-11 GO:0060284 regulation of cell development
1.51 1.60e-11 GO:0051128 regulation of cellular component organization
1.53 1.89e-11 GO:0010557 positive regulation of macromolecule biosynthetic process
1.56 2.31e-11 GO:0009719 response to endogenous stimulus
1.45 2.65e-11 GO:0009605 response to external stimulus
1.80 2.73e-11 GO:0007411 axon guidance
1.63 3.19e-11 GO:0045892 negative regulation of transcription, DNA-dependent
1.81 5.75e-11 GO:0001501 skeletal system development
1.24 7.18e-11 GO:0006810 transport
1.66 7.76e-11 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.61 8.28e-11 GO:0051253 negative regulation of RNA metabolic process
2.09 9.60e-11 GO:0030900 forebrain development
1.24 1.08e-10 GO:0051234 establishment of localization
1.30 1.23e-10 GO:0043412 macromolecule modification
1.38 1.36e-10 GO:0010033 response to organic substance
1.42 1.62e-10 GO:0010646 regulation of cell communication
1.53 2.82e-10 GO:0009790 embryo development
1.43 3.36e-10 GO:0006793 phosphorus metabolic process
1.43 3.36e-10 GO:0006796 phosphate metabolic process
2.02 3.49e-10 GO:0048732 gland development
1.64 3.68e-10 GO:0072358 cardiovascular system development
1.64 3.68e-10 GO:0072359 circulatory system development
1.35 4.78e-10 GO:0009966 regulation of signal transduction
1.56 5.83e-10 GO:0009725 response to hormone stimulus
1.61 6.81e-10 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.50 1.15e-09 GO:0006468 protein phosphorylation
1.46 1.24e-09 GO:0009888 tissue development
1.82 1.37e-09 GO:0051960 regulation of nervous system development
1.55 1.55e-09 GO:0010629 negative regulation of gene expression
1.24 2.37e-09 GO:0071842 cellular component organization at cellular level
1.17 3.19e-09 GO:0044260 cellular macromolecule metabolic process
1.52 3.62e-09 GO:0010558 negative regulation of macromolecule biosynthetic process
1.43 4.64e-09 GO:0009611 response to wounding
1.13 4.91e-09 GO:0044237 cellular metabolic process
1.16 5.01e-09 GO:0043170 macromolecule metabolic process
1.53 5.04e-09 GO:0051172 negative regulation of nitrogen compound metabolic process
1.52 5.99e-09 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.49 6.52e-09 GO:0009890 negative regulation of biosynthetic process
1.41 7.30e-09 GO:0032774 RNA biosynthetic process
1.53 8.39e-09 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.63 8.51e-09 GO:0032583 regulation of gene-specific transcription
1.33 9.89e-09 GO:0065009 regulation of molecular function
1.49 1.16e-08 GO:0031327 negative regulation of cellular biosynthetic process
1.63 1.91e-08 GO:0016477 cell migration
1.42 3.40e-08 GO:0006811 ion transport
1.53 3.68e-08 GO:0050878 regulation of body fluid levels
1.33 4.18e-08 GO:0035556 intracellular signal transduction
1.81 4.97e-08 GO:0050767 regulation of neurogenesis
1.13 5.19e-08 GO:0044238 primary metabolic process
1.69 5.55e-08 GO:0044057 regulation of system process
1.68 7.39e-08 GO:0007389 pattern specification process
1.42 8.58e-08 GO:0016310 phosphorylation
1.55 9.31e-08 GO:0006935 chemotaxis
1.55 9.31e-08 GO:0042330 taxis
1.58 1.11e-07 GO:0048870 cell motility
1.58 1.11e-07 GO:0051674 localization of cell
1.62 1.50e-07 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.67 2.13e-07 GO:0045597 positive regulation of cell differentiation
1.21 2.69e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.64 2.70e-07 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.59 2.75e-07 GO:0008285 negative regulation of cell proliferation
1.86 2.94e-07 GO:0045664 regulation of neuron differentiation
1.71 3.27e-07 GO:0001944 vasculature development
1.49 4.56e-07 GO:0042060 wound healing
1.57 5.00e-07 GO:0046903 secretion
1.73 5.10e-07 GO:0001568 blood vessel development
1.11 5.42e-07 GO:0008152 metabolic process
1.66 6.11e-07 GO:0051093 negative regulation of developmental process
1.49 1.27e-06 GO:0006928 cellular component movement
1.36 1.30e-06 GO:0009892 negative regulation of metabolic process
1.64 1.31e-06 GO:0043434 response to peptide hormone stimulus
1.63 2.20e-06 GO:0071495 cellular response to endogenous stimulus
1.68 2.24e-06 GO:0051270 regulation of cellular component movement
1.63 2.84e-06 GO:0032535 regulation of cellular component size
1.40 3.09e-06 GO:0048584 positive regulation of response to stimulus
1.59 3.88e-06 GO:0009792 embryo development ending in birth or egg hatching
1.37 4.03e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.94 4.48e-06 GO:0045165 cell fate commitment
1.37 4.70e-06 GO:0031324 negative regulation of cellular metabolic process
1.58 4.98e-06 GO:0090066 regulation of anatomical structure size
1.94 5.96e-06 GO:0001655 urogenital system development
1.21 6.85e-06 GO:0006950 response to stress
2.22 8.34e-06 GO:0030879 mammary gland development
1.72 1.27e-05 GO:0048568 embryonic organ development
1.57 1.29e-05 GO:0043009 chordate embryonic development
1.43 1.30e-05 GO:0071310 cellular response to organic substance
1.49 1.61e-05 GO:0030001 metal ion transport
1.49 1.80e-05 GO:0007599 hemostasis
1.65 1.85e-05 GO:0035295 tube development
1.49 1.87e-05 GO:0007596 blood coagulation
1.49 1.87e-05 GO:0050817 coagulation
1.53 2.14e-05 GO:0007243 intracellular protein kinase cascade
1.53 2.14e-05 GO:0023014 signal transduction via phosphorylation event
1.32 2.26e-05 GO:0010941 regulation of cell death
2.30 2.32e-05 GO:0048638 regulation of developmental growth
1.51 2.39e-05 GO:0008283 cell proliferation
2.06 3.07e-05 GO:0010720 positive regulation of cell development
2.22 3.23e-05 GO:0032355 response to estradiol stimulus
1.66 4.06e-05 GO:0008361 regulation of cell size
1.32 4.50e-05 GO:0043067 regulation of programmed cell death
1.60 4.62e-05 GO:0032870 cellular response to hormone stimulus
1.61 4.82e-05 GO:0048729 tissue morphogenesis
1.65 5.26e-05 GO:0045596 negative regulation of cell differentiation
1.66 5.27e-05 GO:0030334 regulation of cell migration
1.19 5.73e-05 GO:0044267 cellular protein metabolic process
1.83 6.27e-05 GO:0006813 potassium ion transport
1.63 6.68e-05 GO:0048545 response to steroid hormone stimulus
2.24 7.26e-05 GO:0022612 gland morphogenesis
1.48 7.28e-05 GO:0048646 anatomical structure formation involved in morphogenesis
1.98 7.37e-05 GO:0060541 respiratory system development
2.09 7.96e-05 GO:0021537 telencephalon development
1.50 8.39e-05 GO:0060341 regulation of cellular localization
1.92 8.62e-05 GO:0048705 skeletal system morphogenesis
2.07 9.56e-05 GO:0030324 lung development
1.17 1.13e-04 GO:0019538 protein metabolic process
1.63 1.13e-04 GO:2000145 regulation of cell motility
1.92 1.15e-04 GO:0022604 regulation of cell morphogenesis
1.33 1.16e-04 GO:0070887 cellular response to chemical stimulus
1.53 1.20e-04 GO:0048598 embryonic morphogenesis
1.81 1.23e-04 GO:0009952 anterior/posterior pattern formation
1.90 1.26e-04 GO:0043627 response to estrogen stimulus
1.59 1.26e-04 GO:0051130 positive regulation of cellular component organization
1.31 1.37e-04 GO:0042981 regulation of apoptosis
1.57 1.40e-04 GO:0051050 positive regulation of transport
1.66 1.50e-04 GO:0003002 regionalization
1.60 1.70e-04 GO:0040012 regulation of locomotion
1.93 1.84e-04 GO:0033273 response to vitamin
1.83 1.93e-04 GO:0031344 regulation of cell projection organization
1.66 1.95e-04 GO:0051129 negative regulation of cellular component organization
2.73 1.99e-04 GO:0061180 mammary gland epithelium development
2.22 2.15e-04 GO:0050770 regulation of axonogenesis
1.90 2.22e-04 GO:0001763 morphogenesis of a branching structure
1.90 2.22e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.98 2.32e-04 GO:0061138 morphogenesis of a branching epithelium
1.96 2.62e-04 GO:0072001 renal system development
1.41 2.76e-04 GO:0006812 cation transport
3.02 2.94e-04 GO:0031128 developmental induction
3.02 2.94e-04 GO:0045168 cell-cell signaling involved in cell fate commitment
2.00 3.60e-04 GO:0030323 respiratory tube development
1.43 3.64e-04 GO:0023056 positive regulation of signaling
1.43 3.80e-04 GO:0010647 positive regulation of cell communication
1.65 4.28e-04 GO:0002009 morphogenesis of an epithelium
1.58 4.54e-04 GO:0007423 sensory organ development
1.28 4.62e-04 GO:0050790 regulation of catalytic activity
1.55 4.62e-04 GO:0032940 secretion by cell
1.96 4.65e-04 GO:0001822 kidney development
1.27 4.66e-04 GO:0002376 immune system process
1.81 4.74e-04 GO:0043269 regulation of ion transport
2.01 4.79e-04 GO:0030278 regulation of ossification
2.24 4.84e-04 GO:0032526 response to retinoic acid
2.39 5.37e-04 GO:0070848 response to growth factor stimulus
1.88 5.68e-04 GO:0010959 regulation of metal ion transport
1.42 6.05e-04 GO:0008284 positive regulation of cell proliferation
1.29 6.06e-04 GO:0051246 regulation of protein metabolic process
2.79 7.19e-04 GO:0060443 mammary gland morphogenesis
1.66 7.23e-04 GO:0048514 blood vessel morphogenesis
1.43 7.58e-04 GO:0009967 positive regulation of signal transduction
1.87 8.15e-04 GO:0010975 regulation of neuron projection development
1.36 8.29e-04 GO:0019220 regulation of phosphate metabolic process
1.36 8.29e-04 GO:0051174 regulation of phosphorus metabolic process
2.42 8.71e-04 GO:0001649 osteoblast differentiation
1.62 9.08e-04 GO:0030168 platelet activation
1.69 9.24e-04 GO:0007517 muscle organ development
1.42 9.35e-04 GO:0001775 cell activation
1.34 9.45e-04 GO:0016192 vesicle-mediated transport
1.68 1.21e-03 GO:0007584 response to nutrient
1.69 1.56e-03 GO:0051051 negative regulation of transport
1.45 1.82e-03 GO:0040008 regulation of growth
1.60 1.85e-03 GO:0040007 growth
1.37 1.88e-03 GO:0048878 chemical homeostasis
1.94 2.19e-03 GO:0048754 branching morphogenesis of a tube
1.44 2.26e-03 GO:0006873 cellular ion homeostasis
1.74 2.36e-03 GO:0048562 embryonic organ morphogenesis
1.72 2.47e-03 GO:0051272 positive regulation of cellular component movement
3.03 2.72e-03 GO:0003156 regulation of organ formation
1.36 2.84e-03 GO:0001932 regulation of protein phosphorylation
1.55 2.92e-03 GO:0061061 muscle structure development
1.79 3.36e-03 GO:0001503 ossification
1.30 3.36e-03 GO:0016265 death
1.39 3.36e-03 GO:0010942 positive regulation of cell death
1.51 3.38e-03 GO:0007610 behavior
1.20 3.75e-03 GO:0010467 gene expression
2.20 4.27e-03 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.34 4.40e-03 GO:0042325 regulation of phosphorylation
1.39 4.52e-03 GO:0043068 positive regulation of programmed cell death
1.27 4.53e-03 GO:0032268 regulation of cellular protein metabolic process
1.42 4.56e-03 GO:0055082 cellular chemical homeostasis
1.30 4.70e-03 GO:0008219 cell death
2.16 5.44e-03 GO:0051494 negative regulation of cytoskeleton organization
2.04 5.46e-03 GO:0033189 response to vitamin A
1.62 5.66e-03 GO:0001701 in utero embryonic development
1.70 5.72e-03 GO:0070482 response to oxygen levels
1.85 5.95e-03 GO:0003001 generation of a signal involved in cell-cell signaling
1.85 5.95e-03 GO:0023061 signal release
2.76 6.45e-03 GO:0050803 regulation of synapse structure and activity
1.75 6.72e-03 GO:0050678 regulation of epithelial cell proliferation
1.73 7.04e-03 GO:0034330 cell junction organization
1.56 7.23e-03 GO:0000165 MAPKKK cascade
1.56 7.23e-03 GO:0051241 negative regulation of multicellular organismal process
2.05 7.28e-03 GO:2000027 regulation of organ morphogenesis
1.31 7.39e-03 GO:0031399 regulation of protein modification process
1.39 7.80e-03 GO:0043065 positive regulation of apoptosis
2.90 7.93e-03 GO:0050807 regulation of synapse organization
2.99 8.30e-03 GO:0060603 mammary gland duct morphogenesis
2.17 9.53e-03 GO:0021543 pallium development
1.71 9.55e-03 GO:0030335 positive regulation of cell migration
1.71 9.55e-03 GO:2000147 positive regulation of cell motility
2.23 9.73e-03 GO:0060348 bone development
2.58 1.05e-02 GO:0002088 lens development in camera-type eye
1.57 1.06e-02 GO:0071375 cellular response to peptide hormone stimulus
1.74 1.16e-02 GO:0048589 developmental growth
1.72 1.21e-02 GO:0031644 regulation of neurological system process
2.32 1.22e-02 GO:0009880 embryonic pattern specification
2.32 1.22e-02 GO:0048663 neuron fate commitment
2.32 1.22e-02 GO:0060021 palate development
1.23 1.29e-02 GO:0051641 cellular localization
1.47 1.39e-02 GO:0015672 monovalent inorganic cation transport
1.50 1.40e-02 GO:0031667 response to nutrient levels
1.20 1.42e-02 GO:0034645 cellular macromolecule biosynthetic process
2.02 1.51e-02 GO:0031346 positive regulation of cell projection organization
1.30 1.54e-02 GO:0007155 cell adhesion
1.30 1.54e-02 GO:0022610 biological adhesion
1.60 1.54e-02 GO:0044087 regulation of cellular component biogenesis
1.45 1.62e-02 GO:0018193 peptidyl-amino acid modification
1.62 1.64e-02 GO:0035239 tube morphogenesis
2.47 1.74e-02 GO:0071363 cellular response to growth factor stimulus
1.39 1.87e-02 GO:0050801 ion homeostasis
1.73 2.01e-02 GO:0034329 cell junction assembly
1.55 2.06e-02 GO:0032868 response to insulin stimulus
1.24 2.09e-02 GO:0051649 establishment of localization in cell
1.49 2.12e-02 GO:0042493 response to drug
1.69 2.16e-02 GO:0034762 regulation of transmembrane transport
1.68 2.18e-02 GO:0001666 response to hypoxia
1.80 2.18e-02 GO:0007611 learning or memory
3.93 2.29e-02 GO:0071548 response to dexamethasone stimulus
2.06 2.30e-02 GO:0007269 neurotransmitter secretion
1.46 2.34e-02 GO:0051046 regulation of secretion
1.39 2.38e-02 GO:0060548 negative regulation of cell death
1.84 2.47e-02 GO:0045761 regulation of adenylate cyclase activity
1.19 2.48e-02 GO:0009059 macromolecule biosynthetic process
1.59 2.51e-02 GO:0003013 circulatory system process
1.59 2.51e-02 GO:0008015 blood circulation
1.25 2.51e-02 GO:0022607 cellular component assembly
1.35 2.63e-02 GO:0019725 cellular homeostasis
1.61 2.71e-02 GO:0014070 response to organic cyclic compound
1.56 2.89e-02 GO:0043193 positive regulation of gene-specific transcription
1.53 2.98e-02 GO:0007507 heart development
1.78 3.01e-02 GO:0019933 cAMP-mediated signaling
1.86 3.07e-02 GO:0051216 cartilage development
1.59 3.28e-02 GO:0032582 negative regulation of gene-specific transcription
1.75 3.32e-02 GO:0050890 cognition
2.57 3.36e-02 GO:0061035 regulation of cartilage development
1.73 3.40e-02 GO:0030802 regulation of cyclic nucleotide biosynthetic process
1.73 3.40e-02 GO:0030808 regulation of nucleotide biosynthetic process
2.10 3.41e-02 GO:0009798 axis specification
1.72 3.47e-02 GO:0030799 regulation of cyclic nucleotide metabolic process
1.70 3.58e-02 GO:0060191 regulation of lipase activity
1.81 3.65e-02 GO:0051339 regulation of lyase activity
1.81 3.65e-02 GO:0051924 regulation of calcium ion transport
1.53 3.66e-02 GO:0001558 regulation of cell growth
1.65 3.70e-02 GO:0040017 positive regulation of locomotion
1.41 4.02e-02 GO:0060429 epithelium development
1.38 4.09e-02 GO:0016044 cellular membrane organization
2.62 4.10e-02 GO:0043535 regulation of blood vessel endothelial cell migration
1.77 4.12e-02 GO:0043583 ear development
1.91 4.30e-02 GO:0050769 positive regulation of neurogenesis
1.70 4.69e-02 GO:0042391 regulation of membrane potential
1.80 4.84e-02 GO:0031279 regulation of cyclase activity

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.43 3.28e-28 GO:0044459 plasma membrane part
1.46 1.07e-17 GO:0031226 intrinsic to plasma membrane
1.46 2.27e-17 GO:0005887 integral to plasma membrane
1.85 3.00e-17 GO:0043005 neuron projection
1.76 4.33e-14 GO:0045202 synapse
1.11 2.47e-11 GO:0005737 cytoplasm
1.19 4.26e-11 GO:0005886 plasma membrane
1.18 2.77e-10 GO:0071944 cell periphery
1.38 4.35e-10 GO:0000267 cell fraction
1.07 5.39e-10 GO:0044424 intracellular part
1.73 2.97e-09 GO:0044456 synapse part
1.42 3.67e-09 GO:0042995 cell projection
1.07 4.01e-09 GO:0005622 intracellular
1.94 4.80e-09 GO:0030424 axon
1.41 2.36e-08 GO:0005626 insoluble fraction
1.41 5.03e-08 GO:0005624 membrane fraction
1.84 1.42e-07 GO:0030425 dendrite
1.86 2.05e-07 GO:0044297 cell body
1.87 2.53e-07 GO:0043025 neuronal cell body
1.45 3.54e-07 GO:0030054 cell junction
1.03 1.53e-06 GO:0005623 cell
1.03 1.96e-06 GO:0044464 cell part
1.74 2.16e-06 GO:0034702 ion channel complex
1.92 2.84e-06 GO:0034703 cation channel complex
1.36 6.44e-06 GO:0031982 vesicle
1.20 5.99e-05 GO:0005829 cytosol
1.35 6.42e-05 GO:0031988 membrane-bounded vesicle
1.29 6.61e-05 GO:0044421 extracellular region part
1.49 7.08e-05 GO:0031012 extracellular matrix
2.12 7.89e-05 GO:0033267 axon part
1.32 2.22e-04 GO:0031410 cytoplasmic vesicle
1.72 5.73e-04 GO:0045211 postsynaptic membrane
1.15 6.16e-04 GO:0043234 protein complex
1.32 6.16e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.49 7.00e-04 GO:0005578 proteinaceous extracellular matrix
1.56 1.02e-03 GO:0016323 basolateral plasma membrane
1.42 1.19e-03 GO:0044463 cell projection part
1.26 1.66e-03 GO:0005794 Golgi apparatus
1.46 1.77e-03 GO:0044433 cytoplasmic vesicle part
1.29 1.87e-03 GO:0005615 extracellular space
2.44 1.89e-03 GO:0042734 presynaptic membrane
1.90 2.72e-03 GO:0008076 voltage-gated potassium channel complex
1.90 2.72e-03 GO:0034705 potassium channel complex
1.94 3.00e-03 GO:0014069 postsynaptic density
1.49 3.79e-03 GO:0012506 vesicle membrane
2.57 4.62e-03 GO:0034704 calcium channel complex
1.09 4.99e-03 GO:0005634 nucleus
1.48 7.74e-03 GO:0030659 cytoplasmic vesicle membrane
1.78 9.19e-03 GO:0019717 synaptosome
1.31 1.14e-02 GO:0044431 Golgi apparatus part
1.20 1.22e-02 GO:0005654 nucleoplasm
1.53 1.23e-02 GO:0030141 stored secretory granule
1.08 2.37e-02 GO:0044444 cytoplasmic part
1.05 4.25e-02 GO:0043226 organelle
1.90 4.48e-02 GO:0030426 growth cone
1.90 4.48e-02 GO:0031256 leading edge membrane
1.36 4.89e-02 GO:0009986 cell surface

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 2.60e-40 GO:0005515 protein binding
1.11 4.33e-32 GO:0005488 binding
1.60 1.14e-22 GO:0001071 nucleic acid binding transcription factor activity
1.60 1.14e-22 GO:0003700 sequence-specific DNA binding transcription factor activity
1.70 1.11e-20 GO:0043565 sequence-specific DNA binding
1.51 8.55e-17 GO:0030528 transcription regulator activity
1.40 1.49e-09 GO:0005102 receptor binding
1.62 2.87e-09 GO:0015267 channel activity
1.72 3.52e-09 GO:0022836 gated channel activity
1.62 3.68e-09 GO:0022803 passive transmembrane transporter activity
1.77 4.57e-09 GO:0005261 cation channel activity
1.60 5.37e-09 GO:0019904 protein domain specific binding
1.63 6.48e-09 GO:0005216 ion channel activity
1.60 2.79e-08 GO:0022838 substrate-specific channel activity
1.50 4.25e-08 GO:0008324 cation transmembrane transporter activity
1.43 4.78e-08 GO:0019899 enzyme binding
1.47 1.45e-07 GO:0004672 protein kinase activity
1.42 1.74e-07 GO:0015075 ion transmembrane transporter activity
1.96 4.01e-07 GO:0022843 voltage-gated cation channel activity
1.61 2.57e-06 GO:0016563 transcription activator activity
1.39 2.98e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.55 3.47e-06 GO:0000988 protein binding transcription factor activity
1.55 3.47e-06 GO:0000989 transcription factor binding transcription factor activity
1.54 5.47e-06 GO:0003712 transcription cofactor activity
2.54 5.70e-06 GO:0003707 steroid hormone receptor activity
2.47 9.45e-06 GO:0004879 ligand-dependent nuclear receptor activity
1.61 9.61e-06 GO:0008134 transcription factor binding
1.74 1.97e-05 GO:0005244 voltage-gated ion channel activity
1.74 1.97e-05 GO:0022832 voltage-gated channel activity
1.71 2.19e-05 GO:0000975 regulatory region DNA binding
1.71 2.19e-05 GO:0001067 regulatory region nucleic acid binding
1.71 2.19e-05 GO:0044212 transcription regulatory region DNA binding
1.35 2.29e-05 GO:0016301 kinase activity
1.33 2.51e-05 GO:0022891 substrate-specific transmembrane transporter activity
1.57 2.89e-05 GO:0016564 transcription repressor activity
1.19 3.16e-05 GO:0003677 DNA binding
1.31 5.93e-05 GO:0022857 transmembrane transporter activity
1.37 1.14e-04 GO:0046983 protein dimerization activity
1.68 1.45e-04 GO:0010843 promoter binding
1.79 4.00e-04 GO:0004713 protein tyrosine kinase activity
1.76 4.48e-04 GO:0003714 transcription corepressor activity
2.04 4.57e-04 GO:0019199 transmembrane receptor protein kinase activity
1.28 4.67e-04 GO:0022892 substrate-specific transporter activity
2.87 6.63e-04 GO:0005245 voltage-gated calcium channel activity
1.32 9.50e-04 GO:0042802 identical protein binding
1.24 1.11e-03 GO:0005215 transporter activity
1.42 1.23e-03 GO:0004674 protein serine/threonine kinase activity
1.55 1.35e-03 GO:0003702 RNA polymerase II transcription factor activity
1.88 1.36e-03 GO:0005057 receptor signaling protein activity
1.99 2.56e-03 GO:0005262 calcium channel activity
1.55 3.17e-03 GO:0046982 protein heterodimerization activity
1.27 3.34e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.75 3.93e-03 GO:0005267 potassium channel activity
1.50 4.23e-03 GO:0032403 protein complex binding
1.65 4.44e-03 GO:0005085 guanyl-nucleotide exchange factor activity
2.06 6.06e-03 GO:0004714 transmembrane receptor protein tyrosine kinase activity
1.73 6.97e-03 GO:0015276 ligand-gated ion channel activity
1.73 6.97e-03 GO:0022834 ligand-gated channel activity
1.80 1.28e-02 GO:0005249 voltage-gated potassium channel activity
1.83 2.03e-02 GO:0008081 phosphoric diester hydrolase activity
2.52 2.30e-02 GO:0017046 peptide hormone binding
1.34 2.92e-02 GO:0030695 GTPase regulator activity
1.33 3.72e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.35 4.59e-02 GO:0008289 lipid binding