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• Activity deltas table
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Motif ID: HIC1.p2

Z-value: 4.035

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_+_222845	76.681	NM_000517	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr12_+_121078421	72.117	NM_001033677	CABP1	calcium binding protein 1
chr1_+_6845381	56.867	NM_001195563 NM_001242701 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr16_+_226678	50.724	NM_000558	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr19_+_708766	49.337	NM_001040134 NM_002579	PALM	paralemmin
chr14_+_103243832	49.255		TRAF3	TNF receptor-associated factor 3
chr10_+_126150340	48.916	NM_001167880 NM_022126	LHPP	phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr11_-_12030838	47.757		DKK3	dickkopf 3 homolog (Xenopus laevis)
chr15_+_68871285	47.562	NM_006091	CORO2B	coronin, actin binding protein, 2B
chr11_-_12030882	45.209	NM_013253	DKK3	dickkopf 3 homolog (Xenopus laevis)
chr8_+_26435339	43.383	NM_001386	DPYSL2	dihydropyrimidinase-like 2
chr16_+_58497628	43.019		NDRG4	NDRG family member 4
chr9_+_137979513	42.323		OLFM1	olfactomedin 1
chr9_+_130965666	41.660		DNM1	dynamin 1
chr3_+_49027281	41.456	NM_177938 NM_177939	P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr13_+_27131799	41.161	NM_006646	WASF3	WAS protein family, member 3
chr5_-_11904127	40.892		CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr1_+_10270680	40.471	NM_015074 NM_183416	KIF1B	kinesin family member 1B
chr5_-_11903964	40.439	NM_001332	CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr15_-_29862926	40.228	NM_015307	FAM189A1	family with sequence similarity 189, member A1
chr9_+_130965668	39.788		DNM1	dynamin 1
chr9_+_130965608	39.705	NM_001005336 NM_004408	DNM1	dynamin 1
chr12_+_66218879	38.160		HMGA2	high mobility group AT-hook 2
chr19_-_19006868	38.136	NM_021267 NM_198207 NM_001492	CERS1 GDF1	ceramide synthase 1 growth differentiation factor 1
chr11_-_12030539	38.079		DKK3	dickkopf 3 homolog (Xenopus laevis)
chr3_+_49027770	38.005		P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr6_-_84419018	37.562		SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr16_+_58497548	37.326	NM_020465	NDRG4	NDRG family member 4
chr11_-_12030622	37.138	NM_015881	DKK3	dickkopf 3 homolog (Xenopus laevis)
chr11_-_66335958	36.933	NM_003793	CTSF	cathepsin F
chr1_-_11714396	36.028		FBXO2	F-box protein 2
chr2_+_236403290	36.013		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr6_+_7108864	34.127		RREB1	ras responsive element binding protein 1
chr8_-_27472188	34.032		CLU	clusterin
chr7_+_45614179	33.672		ADCY1	adenylate cyclase 1 (brain)
chr2_-_224903933	33.536	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chrX_+_135229536	33.416	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr6_-_112194430	33.109		FYN	FYN oncogene related to SRC, FGR, YES
chr3_+_53528586	32.411		CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr17_+_30813928	32.393	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr19_+_33685489	32.286	NM_002333	LRP3	low density lipoprotein receptor-related protein 3
chr4_-_5894695	32.090	NM_001014809	CRMP1	collapsin response mediator protein 1
chr7_+_1200097	31.833
chr7_+_156742402	31.227	NM_138400	NOM1	nucleolar protein with MIF4G domain 1
chr9_+_17578952	31.124	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr6_+_107811272	30.629	NM_018013	SOBP	sine oculis binding protein homolog (Drosophila)
chr21_+_47878764	30.357	NM_001146114 NM_001146115 NM_001146116 NM_015151 NM_206889 NM_206890 NM_206891	DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr7_-_44365019	29.951	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr10_-_81205091	29.902	NM_153367	ZCCHC24	zinc finger, CCHC domain containing 24
chr2_+_9614636	29.642	NM_001039613	IAH1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr2_+_241938254	29.459	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr9_-_139922705	29.281	NM_001606	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr19_+_33685140	29.115		LRP3	low density lipoprotein receptor-related protein 3
chr8_-_27472298	29.110	NM_001831	CLU	clusterin
chr18_-_5630629	29.071		EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr19_-_460995	29.004	NM_012435	SHC2	SHC (Src homology 2 domain containing) transforming protein 2
chr15_-_43029123	28.989		CDAN1	congenital dyserythropoietic anemia, type I
chr9_-_13279562	28.925		MPDZ	multiple PDZ domain protein
chr5_+_76506705	28.479	NM_001029851 NM_001029852 NM_001029853 NM_001029854 NM_003719	PDE8B	phosphodiesterase 8B
chr17_-_31386	28.399	NM_003585	DOC2B	double C2-like domains, beta
chr11_+_120382420	28.222		GRIK4	glutamate receptor, ionotropic, kainate 4
chr7_-_994259	28.149	NM_006869	ADAP1	ArfGAP with dual PH domains 1
chr18_+_77439798	28.122	NM_004715 NM_048368	CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr9_+_130374466	27.893	NM_001032221 NM_003165	STXBP1	syntaxin binding protein 1
chr1_-_62785067	27.890	NM_181712	KANK4	KN motif and ankyrin repeat domains 4
chr15_-_23086290	27.880	NM_144599	NIPA1	non imprinted in Prader-Willi/Angelman syndrome 1
chr19_-_56632644	27.730	NM_001002836	ZNF787	zinc finger protein 787
chr7_-_158622184	27.570		ESYT2	extended synaptotagmin-like protein 2
chr12_-_124457099	27.526	NM_025140	CCDC92	coiled-coil domain containing 92
chr2_-_99552677	27.502	NM_207362	C2orf55	chromosome 2 open reading frame 55
chr9_-_101470836	27.443	NM_005458	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
chr14_+_100438095	27.237		EVL	Enah/Vasp-like
chr16_+_84002099	26.754	NM_019065	NECAB2	N-terminal EF-hand calcium binding protein 2
chr22_-_21213069	26.497		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr22_-_21213012	26.425		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr7_-_108096693	26.389	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chr1_-_20812727	26.290	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr14_+_92789536	25.701	NM_153647	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr20_+_44034632	25.612	NM_001197139 NM_001048221 NM_001048222 NM_001197140 NM_018478	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr9_+_123963728	25.588		GSN	gelsolin
chr2_-_127864505	25.475	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chr6_-_84419108	25.447	NM_001242793 NM_001242794 NM_014841	SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr13_+_27131879	25.434		WASF3	WAS protein family, member 3
chr1_-_57044980	25.397		PPAP2B	phosphatidic acid phosphatase type 2B
chr10_-_15413054	25.312	NM_001010924	FAM171A1	family with sequence similarity 171, member A1
chr19_-_5340700	25.245	NM_002850 NM_130853 NM_130854 NM_130855	PTPRS	protein tyrosine phosphatase, receptor type, S
chr18_+_77439843	25.192		CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr6_-_84418705	25.054	NM_001242792	SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr11_+_121322848	24.951	NM_003105	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr21_-_46359685	24.902		C21orf67	chromosome 21 open reading frame 67
chr8_+_104152876	24.708	NM_001024372 NM_024812	BAALC	brain and acute leukemia, cytoplasmic
chr10_+_124220990	24.476	NM_002775	HTRA1	HtrA serine peptidase 1
chr3_+_71803200	24.410	NM_018971	GPR27	G protein-coupled receptor 27
chr22_+_33197678	23.964		TIMP3	TIMP metallopeptidase inhibitor 3
chr7_-_158622202	23.906	NM_020728	ESYT2	extended synaptotagmin-like protein 2
chr5_+_7396030	23.853	NM_020546	ADCY2	adenylate cyclase 2 (brain)
chr17_+_18128868	23.784	NM_004140	LLGL1	lethal giant larvae homolog 1 (Drosophila)
chr19_+_35521591	23.755	NM_001037 NM_199037	SCN1B	sodium channel, voltage-gated, type I, beta
chrX_+_38420690	23.706	NM_004615	TSPAN7	tetraspanin 7
chr16_+_58497993	23.361	NM_001130487	NDRG4	NDRG family member 4
chr5_-_58334936	23.235	NM_001197221 NM_001197222	PDE4D	phosphodiesterase 4D, cAMP-specific
chr11_+_1411089	23.202	NM_003957	BRSK2	BR serine/threonine kinase 2
chr22_-_19511777	22.986		CLDN5	claudin 5
chr6_+_39760148	22.962	NM_001201427	DAAM2	dishevelled associated activator of morphogenesis 2
chr11_-_33890931	22.705		LMO2	LIM domain only 2 (rhombotin-like 1)
chr3_+_53529030	22.613	NM_000720 NM_001128839 NM_001128840	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr14_+_96505566	22.570	NM_001252507	C14orf132	chromosome 14 open reading frame 132
chr3_+_11034436	22.489		SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr3_+_32148136	22.455		GPD1L	glycerol-3-phosphate dehydrogenase 1-like
chr4_-_185747051	22.373		ACSL1	acyl-CoA synthetase long-chain family member 1
chr4_+_4388717	22.187		D4S234E	DNA segment on chromosome 4 (unique) 234 expressed sequence
chr19_-_3700387	22.131		PIP5K1C	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
chr14_+_105155724	22.099	NM_001031714 NM_022489 NM_032714	INF2	inverted formin, FH2 and WH2 domain containing
chr15_+_41851153	21.990	NM_006293	TYRO3	TYRO3 protein tyrosine kinase
chr15_+_80696569	21.910	NM_014862	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr2_-_224903324	21.839	NM_001136530	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr9_+_124030413	21.700		GSN	gelsolin
chr9_-_135996287	21.410	NM_006266	RALGDS	ral guanine nucleotide dissociation stimulator
chr13_-_40177304	21.309		LHFP	lipoma HMGIC fusion partner
chr4_+_95679075	21.304	NM_001203	BMPR1B	bone morphogenetic protein receptor, type IB
chr11_-_33891258	21.284		LMO2	LIM domain only 2 (rhombotin-like 1)
chr17_-_10101854	21.223	NM_201433	GAS7	growth arrest-specific 7
chr14_+_92790151	21.163	NM_153646	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_-_45267804	21.045	NM_015444	TMEM158	transmembrane protein 158 (gene/pseudogene)
chr14_+_105780903	21.019		PACS2	phosphofurin acidic cluster sorting protein 2
chr9_-_139922595	21.002		ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr1_+_244998592	20.941	NM_198076	FAM36A	family with sequence similarity 36, member A
chr10_-_118501981	20.882	NM_025015	HSPA12A	heat shock 70kDa protein 12A
chr8_+_26435466	20.788		DPYSL2	dihydropyrimidinase-like 2
chrX_+_153237990	20.664	NM_003492	TMEM187	transmembrane protein 187
chr12_-_93323006	20.629		EEA1	early endosome antigen 1
chr6_+_147829784	20.558	NM_001030060	SAMD5	sterile alpha motif domain containing 5
chr9_+_124030370	20.415	NM_001127662 NM_001127663 NM_001127664 NM_001127665 NM_001127666 NM_001127667 NM_198252	GSN	gelsolin
chr9_+_103235634	20.382		TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr18_-_21977711	20.310		OSBPL1A	oxysterol binding protein-like 1A
chr19_-_6279927	20.296	NM_005934	MLLT1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr11_-_62554790	20.191
chr10_+_121485593	20.176		INPP5F	inositol polyphosphate-5-phosphatase F
chr2_-_27718098	20.146	NM_022823	FNDC4	fibronectin type III domain containing 4
chr11_-_113746205	20.075	NM_020886	USP28	ubiquitin specific peptidase 28
chr17_-_8066254	20.063	NM_014232	VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr3_-_127541975	19.938	NM_001003794	MGLL	monoglyceride lipase
chr5_+_134240820	19.929		PCBD2	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr10_+_124134206	19.879		PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_+_201476283	19.715
chr19_-_3700466	19.703	NM_001195733 NM_012398	PIP5K1C	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
chr9_+_124030455	19.701		GSN	gelsolin
chr22_-_21213099	19.700	NM_058004	PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr12_+_4918341	19.649	NM_002235	KCNA6	potassium voltage-gated channel, shaker-related subfamily, member 6
chr12_-_93323088	19.573	NM_003566	EEA1	early endosome antigen 1
chr7_+_45614081	19.567	NM_021116	ADCY1	adenylate cyclase 1 (brain)
chr15_+_100106214	19.550		MEF2A	myocyte enhancer factor 2A
chr12_-_93322911	19.535		EEA1	early endosome antigen 1
chr17_+_64298731	19.458		PRKCA	protein kinase C, alpha
chr2_-_69870705	19.420		AAK1	AP2 associated kinase 1
chr19_+_54926721	19.333		TTYH1	tweety homolog 1 (Drosophila)
chr4_-_185747183	19.311	NM_001995	ACSL1	acyl-CoA synthetase long-chain family member 1
chr10_+_121485638	19.274		INPP5F	inositol polyphosphate-5-phosphatase F
chr2_+_46524448	19.173	NM_001430	EPAS1	endothelial PAS domain protein 1
chr20_+_44035203	19.147	NM_001048223 NM_001048224	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr4_-_8873453	19.132	NM_018942	HMX1	H6 family homeobox 1
chr2_-_69870837	19.053		AAK1	AP2 associated kinase 1
chr19_-_11373117	19.014	NM_020812	DOCK6	dedicator of cytokinesis 6
chr5_+_92920592	18.915		NR2F1 NR2F2	nuclear receptor subfamily 2, group F, member 1 nuclear receptor subfamily 2, group F, member 2
chr18_+_74534458	18.815		ZNF236	zinc finger protein 236
chr1_-_32229635	18.808	NM_001703	BAI2	brain-specific angiogenesis inhibitor 2
chr5_+_134240752	18.710	NM_032151	PCBD2	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr22_-_18923654	18.708		PRODH	proline dehydrogenase (oxidase) 1
chr7_-_140624280	18.702	NM_004333	BRAF	v-raf murine sarcoma viral oncogene homolog B1
chr21_+_47878969	18.671		DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr13_+_42031690	18.656		C13orf15	chromosome 13 open reading frame 15
chr3_+_32148000	18.652	NM_015141	GPD1L	glycerol-3-phosphate dehydrogenase 1-like
chr22_-_19512001	18.649		CLDN5	claudin 5
chr22_+_33197744	18.624		TIMP3	TIMP metallopeptidase inhibitor 3
chr17_-_74449220	18.622		UBE2O	ubiquitin-conjugating enzyme E2O
chr11_-_134281725	18.583	NM_018644 NM_054025	B3GAT1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr7_-_51384458	18.577	NM_015198	COBL	cordon-bleu homolog (mouse)
chr22_-_39151979	18.561		SUN2	Sad1 and UNC84 domain containing 2
chr13_+_98795710	18.533		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr16_+_11762235	18.511	NM_003498	SNN	stannin
chr13_-_44361032	18.498	NM_001242863 NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr4_+_3768295	18.498	NM_000683	ADRA2C	adrenergic, alpha-2C-, receptor
chr15_+_92397027	18.454		SLCO3A1	solute carrier organic anion transporter family, member 3A1
chr7_-_150038689	18.282	NM_002889	RARRES2	retinoic acid receptor responder (tazarotene induced) 2
chr12_-_53574690	18.258	NM_001244705	CSAD	cysteine sulfinic acid decarboxylase
chr1_+_236305831	18.229	NM_003272	GPR137B	G protein-coupled receptor 137B
chr17_-_74236272	18.223	NM_052916	RNF157	ring finger protein 157
chr14_-_105886075	18.191		LOC100507437	uncharacterized LOC100507437
chr4_-_16228071	18.159		TAPT1	transmembrane anterior posterior transformation 1
chr10_+_116853118	18.155	NM_207303	ATRNL1	attractin-like 1
chr17_+_7554711	18.077		ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr8_+_1922030	18.054	NM_014867	KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr10_+_121485487	18.034	NM_001243195 NM_014937	INPP5F	inositol polyphosphate-5-phosphatase F
chr1_-_2322996	17.968		MORN1	MORN repeat containing 1
chr3_-_14988976	17.942		LOC100505641	uncharacterized LOC100505641
chr9_+_103235489	17.867	NM_003692	TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr1_+_19970674	17.861	NM_005380	NBL1	neuroblastoma, suppression of tumorigenicity 1
chr7_+_98246595	17.768	NM_002523	NPTX2	neuronal pentraxin II
chr10_+_49514652	17.765		MAPK8	mitogen-activated protein kinase 8
chr19_-_18717631	17.748	NM_004750	CRLF1	cytokine receptor-like factor 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.43	7.32e-46	GO:0032502	developmental process
1.45	4.73e-44	GO:0007275	multicellular organismal development
1.27	1.05e-43	GO:0050794	regulation of cellular process
1.72	1.84e-40	GO:0007399	nervous system development
1.24	1.88e-40	GO:0065007	biological regulation
1.15	5.87e-40	GO:0009987	cellular process
1.25	8.53e-40	GO:0050789	regulation of biological process
1.45	1.36e-39	GO:0048856	anatomical structure development
1.48	1.96e-39	GO:0048731	system development
1.55	3.35e-35	GO:0048869	cellular developmental process
1.55	1.12e-34	GO:0030154	cell differentiation
1.38	2.59e-33	GO:0023052	signaling
1.60	1.31e-31	GO:0023051	regulation of signaling
1.62	1.04e-29	GO:0009653	anatomical structure morphogenesis
1.77	4.55e-27	GO:0022008	neurogenesis
1.79	1.77e-26	GO:0048699	generation of neurons
1.36	3.93e-26	GO:0007165	signal transduction
1.58	7.90e-25	GO:0009966	regulation of signal transduction
1.74	9.09e-25	GO:0048468	cell development
2.02	1.18e-24	GO:0000904	cell morphogenesis involved in differentiation
1.85	2.58e-24	GO:0030182	neuron differentiation
1.92	4.48e-24	GO:0000902	cell morphogenesis
1.93	7.56e-24	GO:0048666	neuron development
1.25	8.71e-24	GO:0032501	multicellular organismal process
1.99	3.04e-23	GO:0048858	cell projection morphogenesis
2.05	4.13e-23	GO:0048812	neuron projection morphogenesis
2.05	8.41e-23	GO:0048667	cell morphogenesis involved in neuron differentiation
1.97	1.23e-22	GO:0032990	cell part morphogenesis
1.86	2.99e-22	GO:0032989	cellular component morphogenesis
1.97	1.06e-21	GO:0031175	neuron projection development
2.05	1.07e-21	GO:0007409	axonogenesis
1.84	1.26e-21	GO:0030030	cell projection organization
1.28	6.87e-20	GO:0051716	cellular response to stimulus
1.45	2.17e-19	GO:0007166	cell surface receptor linked signaling pathway
1.78	4.34e-19	GO:0007167	enzyme linked receptor protein signaling pathway
1.43	1.12e-18	GO:0048583	regulation of response to stimulus
1.59	1.51e-18	GO:0010646	regulation of cell communication
1.38	2.41e-18	GO:0048519	negative regulation of biological process
1.51	4.48e-18	GO:0035556	intracellular signal transduction
1.39	1.70e-17	GO:0048523	negative regulation of cellular process
1.84	6.15e-17	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.84	6.77e-17	GO:0007417	central nervous system development
1.41	1.26e-16	GO:0048513	organ development
1.28	2.14e-16	GO:0031323	regulation of cellular metabolic process
1.26	3.36e-16	GO:0019222	regulation of metabolic process
2.01	1.37e-15	GO:0007411	axon guidance
1.27	2.41e-15	GO:0080090	regulation of primary metabolic process
1.35	1.07e-14	GO:0042221	response to chemical stimulus
1.78	8.50e-14	GO:0019226	transmission of nerve impulse
1.78	8.50e-14	GO:0035637	multicellular organismal signaling
1.53	2.39e-13	GO:0032879	regulation of localization
1.55	4.46e-13	GO:0050793	regulation of developmental process
1.45	5.90e-13	GO:0051239	regulation of multicellular organismal process
1.80	9.52e-13	GO:0007268	synaptic transmission
1.29	1.13e-12	GO:0048518	positive regulation of biological process
1.31	1.54e-12	GO:0048522	positive regulation of cellular process
1.25	2.29e-12	GO:0051179	localization
1.54	6.72e-12	GO:0040011	locomotion
1.66	7.22e-12	GO:0009887	organ morphogenesis
1.36	7.35e-12	GO:0006464	protein modification process
1.74	1.13e-11	GO:0072358	cardiovascular system development
1.74	1.13e-11	GO:0072359	circulatory system development
1.61	1.39e-11	GO:0045595	regulation of cell differentiation
1.49	1.91e-11	GO:0006793	phosphorus metabolic process
1.49	1.91e-11	GO:0006796	phosphate metabolic process
1.25	1.93e-11	GO:0016043	cellular component organization
1.58	2.19e-11	GO:0006468	protein phosphorylation
1.24	1.16e-10	GO:0060255	regulation of macromolecule metabolic process
1.81	1.46e-10	GO:0007420	brain development
1.31	1.98e-10	GO:0065008	regulation of biological quality
1.27	4.35e-10	GO:0031326	regulation of cellular biosynthetic process
1.26	5.94e-10	GO:0009889	regulation of biosynthetic process
1.32	7.08e-10	GO:0043412	macromolecule modification
1.53	1.21e-09	GO:2000026	regulation of multicellular organismal development
1.27	1.39e-09	GO:0071842	cellular component organization at cellular level
1.53	1.43e-09	GO:0007267	cell-cell signaling
1.26	1.93e-09	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45	3.16e-09	GO:0007154	cell communication
1.68	3.98e-09	GO:0051094	positive regulation of developmental process
1.22	5.87e-09	GO:0071840	cellular component organization or biogenesis
1.85	6.42e-09	GO:0001944	vasculature development
1.48	7.09e-09	GO:0016310	phosphorylation
1.47	9.18e-09	GO:0006351	transcription, DNA-dependent
1.25	9.32e-09	GO:0051171	regulation of nitrogen compound metabolic process
1.36	9.93e-09	GO:0065009	regulation of molecular function
1.78	1.06e-08	GO:0045597	positive regulation of cell differentiation
1.26	1.30e-08	GO:0010468	regulation of gene expression
1.54	1.34e-08	GO:0009719	response to endogenous stimulus
1.56	1.35e-08	GO:0001932	regulation of protein phosphorylation
1.14	2.93e-08	GO:0044237	cellular metabolic process
1.23	3.67e-08	GO:0051234	establishment of localization
1.52	6.65e-08	GO:0042325	regulation of phosphorylation
1.51	6.98e-08	GO:0019220	regulation of phosphate metabolic process
1.51	6.98e-08	GO:0051174	regulation of phosphorus metabolic process
1.55	7.03e-08	GO:0009725	response to hormone stimulus
1.22	1.91e-07	GO:0006810	transport
1.54	2.09e-07	GO:0010629	negative regulation of gene expression
1.69	2.16e-07	GO:0051056	regulation of small GTPase mediated signal transduction
1.89	2.24e-07	GO:0048011	nerve growth factor receptor signaling pathway
1.58	3.14e-07	GO:0006935	chemotaxis
1.58	3.14e-07	GO:0042330	taxis
1.41	3.23e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.23	3.33e-07	GO:0071841	cellular component organization or biogenesis at cellular level
1.62	4.00e-07	GO:0023057	negative regulation of signaling
1.50	4.05e-07	GO:0010628	positive regulation of gene expression
1.48	4.09e-07	GO:0051049	regulation of transport
1.62	4.92e-07	GO:0010648	negative regulation of cell communication
1.80	5.87e-07	GO:0001568	blood vessel development
1.76	7.03e-07	GO:0051270	regulation of cellular component movement
1.26	7.29e-07	GO:0006355	regulation of transcription, DNA-dependent
1.44	9.78e-07	GO:0051128	regulation of cellular component organization
1.24	1.02e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.55	1.30e-06	GO:0045892	negative regulation of transcription, DNA-dependent
1.69	1.45e-06	GO:0071495	cellular response to endogenous stimulus
1.76	1.52e-06	GO:0051960	regulation of nervous system development
1.13	1.63e-06	GO:0050896	response to stimulus
1.23	1.71e-06	GO:0010556	regulation of macromolecule biosynthetic process
1.58	1.77e-06	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.48	1.91e-06	GO:0031327	negative regulation of cellular biosynthetic process
1.39	2.20e-06	GO:0009892	negative regulation of metabolic process
1.62	2.32e-06	GO:0009968	negative regulation of signal transduction
1.71	2.42e-06	GO:0032870	cellular response to hormone stimulus
1.42	2.52e-06	GO:0009888	tissue development
1.70	2.66e-06	GO:0060284	regulation of cell development
1.47	2.69e-06	GO:0009890	negative regulation of biosynthetic process
1.85	3.02e-06	GO:0048514	blood vessel morphogenesis
1.24	3.09e-06	GO:0051252	regulation of RNA metabolic process
1.48	3.45e-06	GO:0010558	negative regulation of macromolecule biosynthetic process
1.74	3.50e-06	GO:0035295	tube development
1.67	3.96e-06	GO:0044057	regulation of system process
1.52	4.13e-06	GO:0051253	negative regulation of RNA metabolic process
1.48	5.28e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.07	6.34e-06	GO:0001503	ossification
1.39	6.50e-06	GO:0010605	negative regulation of macromolecule metabolic process
1.48	6.81e-06	GO:0045893	positive regulation of transcription, DNA-dependent
1.56	7.15e-06	GO:0048646	anatomical structure formation involved in morphogenesis
1.12	7.37e-06	GO:0044238	primary metabolic process
1.42	7.84e-06	GO:0031399	regulation of protein modification process
1.48	9.01e-06	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38	9.35e-06	GO:0032774	RNA biosynthetic process
1.37	1.06e-05	GO:0009605	response to external stimulus
1.76	1.43e-05	GO:0046578	regulation of Ras protein signal transduction
1.47	1.55e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.62	1.73e-05	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.32	2.12e-05	GO:0009893	positive regulation of metabolic process
1.11	2.75e-05	GO:0008152	metabolic process
1.32	2.96e-05	GO:0010033	response to organic substance
1.65	3.28e-05	GO:0001501	skeletal system development
1.55	3.37e-05	GO:0032583	regulation of gene-specific transcription
1.58	3.84e-05	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.67	4.21e-05	GO:0019932	second-messenger-mediated signaling
1.36	4.32e-05	GO:0042127	regulation of cell proliferation
1.73	4.51e-05	GO:0050767	regulation of neurogenesis
1.64	6.45e-05	GO:0007610	behavior
1.66	6.58e-05	GO:0048729	tissue morphogenesis
1.67	6.66e-05	GO:0040012	regulation of locomotion
1.62	6.84e-05	GO:0043434	response to peptide hormone stimulus
1.35	6.88e-05	GO:0032268	regulation of cellular protein metabolic process
1.50	6.93e-05	GO:0051338	regulation of transferase activity
1.50	7.05e-05	GO:0048585	negative regulation of response to stimulus
1.70	7.09e-05	GO:2000145	regulation of cell motility
1.43	7.32e-05	GO:0051254	positive regulation of RNA metabolic process
1.42	7.38e-05	GO:0009790	embryo development
1.15	7.46e-05	GO:0044260	cellular macromolecule metabolic process
1.70	7.62e-05	GO:0030334	regulation of cell migration
1.33	7.77e-05	GO:0051246	regulation of protein metabolic process
1.52	8.85e-05	GO:0045859	regulation of protein kinase activity
1.32	8.97e-05	GO:0031325	positive regulation of cellular metabolic process
1.37	9.01e-05	GO:0031324	negative regulation of cellular metabolic process
1.54	9.14e-05	GO:0060341	regulation of cellular localization
1.50	9.30e-05	GO:0043549	regulation of kinase activity
1.55	1.09e-04	GO:0016477	cell migration
2.04	1.13e-04	GO:0007265	Ras protein signal transduction
1.96	1.13e-04	GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger
2.19	1.17e-04	GO:0001505	regulation of neurotransmitter levels
1.86	1.23e-04	GO:0030155	regulation of cell adhesion
1.87	1.27e-04	GO:0001525	angiogenesis
1.82	1.38e-04	GO:0014070	response to organic cyclic compound
1.63	1.44e-04	GO:0022603	regulation of anatomical structure morphogenesis
1.90	1.45e-04	GO:0019935	cyclic-nucleotide-mediated signaling
1.56	1.70e-04	GO:0007264	small GTPase mediated signal transduction
1.49	1.76e-04	GO:0009967	positive regulation of signal transduction
1.40	1.78e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
1.57	1.82e-04	GO:0048598	embryonic morphogenesis
1.47	1.91e-04	GO:0010647	positive regulation of cell communication
1.83	2.12e-04	GO:0030900	forebrain development
1.98	2.33e-04	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.30	2.62e-04	GO:0050790	regulation of catalytic activity
1.38	2.71e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
1.46	3.04e-04	GO:0023056	positive regulation of signaling
1.96	3.28e-04	GO:0022604	regulation of cell morphogenesis
2.03	3.30e-04	GO:0019933	cAMP-mediated signaling
1.72	3.43e-04	GO:0071375	cellular response to peptide hormone stimulus
1.68	3.57e-04	GO:0000165	MAPKKK cascade
1.36	3.63e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.55	4.21e-04	GO:0090066	regulation of anatomical structure size
1.75	4.27e-04	GO:0045664	regulation of neuron differentiation
1.60	4.43e-04	GO:0006140	regulation of nucleotide metabolic process
1.36	4.45e-04	GO:0009891	positive regulation of biosynthetic process
1.30	4.71e-04	GO:0010604	positive regulation of macromolecule metabolic process
2.29	5.38e-04	GO:0050770	regulation of axonogenesis
1.70	5.56e-04	GO:0002009	morphogenesis of an epithelium
1.91	6.09e-04	GO:0008286	insulin receptor signaling pathway
1.93	6.39e-04	GO:0048705	skeletal system morphogenesis
2.06	6.54e-04	GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
2.04	6.65e-04	GO:0010720	positive regulation of cell development
1.13	7.70e-04	GO:0043170	macromolecule metabolic process
1.36	8.17e-04	GO:0048584	positive regulation of response to stimulus
1.62	8.69e-04	GO:0007423	sensory organ development
1.91	8.83e-04	GO:0030111	regulation of Wnt receptor signaling pathway
1.92	9.04e-04	GO:0030799	regulation of cyclic nucleotide metabolic process
1.94	9.23e-04	GO:0030802	regulation of cyclic nucleotide biosynthetic process
1.94	9.23e-04	GO:0030808	regulation of nucleotide biosynthetic process
2.04	9.51e-04	GO:0010863	positive regulation of phospholipase C activity
1.58	1.09e-03	GO:0051046	regulation of secretion
1.43	1.18e-03	GO:0006928	cellular component movement
1.37	1.28e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.07	1.31e-03	GO:0051216	cartilage development
1.96	1.35e-03	GO:0030814	regulation of cAMP metabolic process
2.00	1.38e-03	GO:0010518	positive regulation of phospholipase activity
1.59	1.39e-03	GO:0051130	positive regulation of cellular component organization
1.85	1.42e-03	GO:0001655	urogenital system development
2.14	1.68e-03	GO:0060485	mesenchyme development
1.47	1.82e-03	GO:0048870	cell motility
1.47	1.82e-03	GO:0051674	localization of cell
1.97	1.94e-03	GO:0007611	learning or memory
2.01	1.96e-03	GO:0007202	activation of phospholipase C activity
2.01	1.96e-03	GO:0031279	regulation of cyclase activity
1.49	2.08e-03	GO:0007243	intracellular protein kinase cascade
1.49	2.08e-03	GO:0023014	signal transduction via phosphorylation event
1.54	2.14e-03	GO:0007389	pattern specification process
1.48	2.54e-03	GO:0006873	cellular ion homeostasis
1.91	2.56e-03	GO:0050890	cognition
1.62	2.57e-03	GO:0008361	regulation of cell size
2.09	2.62e-03	GO:0060828	regulation of canonical Wnt receptor signaling pathway
1.94	2.68e-03	GO:0030817	regulation of cAMP biosynthetic process
1.95	2.73e-03	GO:0010517	regulation of phospholipase activity
1.98	2.79e-03	GO:0006836	neurotransmitter transport
2.01	2.80e-03	GO:0045761	regulation of adenylate cyclase activity
1.61	2.90e-03	GO:0045596	negative regulation of cell differentiation
2.19	3.07e-03	GO:0048638	regulation of developmental growth
1.38	3.15e-03	GO:0071310	cellular response to organic substance
1.87	3.28e-03	GO:0051969	regulation of transmission of nerve impulse
1.51	3.53e-03	GO:0043009	chordate embryonic development
1.82	3.71e-03	GO:0031644	regulation of neurological system process
1.92	3.71e-03	GO:0050804	regulation of synaptic transmission
1.50	3.81e-03	GO:0009792	embryo development ending in birth or egg hatching
1.97	3.97e-03	GO:0051339	regulation of lyase activity
1.46	4.18e-03	GO:0055082	cellular chemical homeostasis
1.63	4.22e-03	GO:0007507	heart development
1.47	4.30e-03	GO:0040008	regulation of growth
1.53	4.36e-03	GO:0003006	developmental process involved in reproduction
1.53	4.38e-03	GO:0032535	regulation of cellular component size
1.80	4.42e-03	GO:0031344	regulation of cell projection organization
1.63	4.58e-03	GO:0030168	platelet activation
1.47	4.59e-03	GO:0008285	negative regulation of cell proliferation
1.44	4.78e-03	GO:0050801	ion homeostasis
1.91	5.25e-03	GO:0060193	positive regulation of lipase activity
1.83	5.70e-03	GO:0060191	regulation of lipase activity
1.90	7.20e-03	GO:0060541	respiratory system development
1.28	7.28e-03	GO:0010941	regulation of cell death
2.08	7.74e-03	GO:0030178	negative regulation of Wnt receptor signaling pathway
1.93	7.78e-03	GO:0001822	kidney development
1.98	8.11e-03	GO:0007626	locomotory behavior
1.67	8.13e-03	GO:0044087	regulation of cellular component biogenesis
2.00	8.14e-03	GO:0021537	telencephalon development
1.38	8.41e-03	GO:0042060	wound healing
2.98	9.38e-03	GO:0051588	regulation of neurotransmitter transport
1.68	9.48e-03	GO:0032582	negative regulation of gene-specific transcription
1.70	1.01e-02	GO:0032869	cellular response to insulin stimulus
2.10	1.08e-02	GO:0007173	epidermal growth factor receptor signaling pathway
1.68	1.10e-02	GO:0048608	reproductive structure development
1.69	1.19e-02	GO:0035239	tube morphogenesis
1.84	1.22e-02	GO:0010959	regulation of metal ion transport
1.31	1.25e-02	GO:0016265	death
1.38	1.28e-02	GO:0050878	regulation of body fluid levels
1.67	1.29e-02	GO:0043408	regulation of MAPKKK cascade
1.67	1.29e-02	GO:0048732	gland development
1.41	1.49e-02	GO:0007010	cytoskeleton organization
1.28	1.58e-02	GO:0043067	regulation of programmed cell death
2.82	1.59e-02	GO:0021954	central nervous system neuron development
2.05	1.63e-02	GO:0021953	central nervous system neuron differentiation
1.36	1.63e-02	GO:0048878	chemical homeostasis
2.03	1.65e-02	GO:0055123	digestive system development
1.30	1.78e-02	GO:0006811	ion transport
1.30	1.82e-02	GO:0008219	cell death
1.87	1.95e-02	GO:0050796	regulation of insulin secretion
1.64	2.13e-02	GO:0007548	sex differentiation
1.92	2.22e-02	GO:0030323	respiratory tube development
1.93	2.27e-02	GO:0030324	lung development
2.02	2.36e-02	GO:0050769	positive regulation of neurogenesis
1.71	2.52e-02	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
1.40	2.66e-02	GO:0001775	cell activation
1.86	2.74e-02	GO:0072001	renal system development
1.75	2.76e-02	GO:0045926	negative regulation of growth
2.92	2.81e-02	GO:0032231	regulation of actin filament bundle assembly
1.27	3.13e-02	GO:0042981	regulation of apoptosis
1.81	3.19e-02	GO:0002791	regulation of peptide secretion
1.81	3.19e-02	GO:0090087	regulation of peptide transport
1.70	3.20e-02	GO:0051272	positive regulation of cellular component movement
1.49	3.20e-02	GO:0051093	negative regulation of developmental process
1.62	3.27e-02	GO:0043405	regulation of MAP kinase activity
2.07	3.29e-02	GO:0031346	positive regulation of cell projection organization
1.38	3.38e-02	GO:0019725	cellular homeostasis
2.00	3.39e-02	GO:0048706	embryonic skeletal system development
1.70	3.44e-02	GO:0006813	potassium ion transport
1.28	3.91e-02	GO:0070887	cellular response to chemical stimulus
1.37	3.96e-02	GO:0007186	G-protein coupled receptor protein signaling pathway
1.79	3.99e-02	GO:0010975	regulation of neuron projection development
2.34	4.20e-02	GO:0048863	stem cell differentiation
1.67	4.37e-02	GO:0045137	development of primary sexual characteristics
1.81	4.45e-02	GO:0090276	regulation of peptide hormone secretion
1.69	4.70e-02	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.69	4.70e-02	GO:0040017	positive regulation of locomotion
2.04	4.80e-02	GO:0010721	negative regulation of cell development
1.97	4.81e-02	GO:0008016	regulation of heart contraction
1.16	4.90e-02	GO:0044267	cellular protein metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.37	5.59e-18	GO:0044459	plasma membrane part
1.09	1.13e-15	GO:0005622	intracellular
1.09	2.62e-14	GO:0044424	intracellular part
1.12	6.27e-12	GO:0005737	cytoplasm
1.74	5.27e-11	GO:0043005	neuron projection
1.46	1.05e-09	GO:0042995	cell projection
1.38	1.14e-09	GO:0031226	intrinsic to plasma membrane
1.37	5.01e-09	GO:0005887	integral to plasma membrane
1.66	8.90e-09	GO:0045202	synapse
1.44	1.92e-08	GO:0005626	insoluble fraction
1.39	7.52e-08	GO:0005794	Golgi apparatus
1.04	8.19e-08	GO:0044464	cell part
1.04	8.84e-08	GO:0005623	cell
1.42	2.91e-07	GO:0005624	membrane fraction
1.34	1.70e-06	GO:0000267	cell fraction
1.08	9.93e-06	GO:0043226	organelle
1.82	1.73e-05	GO:0030424	axon
1.15	2.00e-05	GO:0005886	plasma membrane
1.07	2.01e-05	GO:0043229	intracellular organelle
1.14	2.81e-05	GO:0071944	cell periphery
2.17	3.41e-05	GO:0008076	voltage-gated potassium channel complex
2.17	3.41e-05	GO:0034705	potassium channel complex
1.43	3.71e-05	GO:0044431	Golgi apparatus part
1.92	4.02e-05	GO:0034703	cation channel complex
1.85	6.52e-05	GO:0005912	adherens junction
1.81	6.86e-05	GO:0070161	anchoring junction
1.21	8.02e-05	GO:0005829	cytosol
1.41	1.35e-04	GO:0030054	cell junction
2.13	4.58e-04	GO:0033267	axon part
1.71	4.86e-04	GO:0031252	cell leading edge
1.55	5.26e-04	GO:0044456	synapse part
1.10	5.99e-04	GO:0044444	cytoplasmic part
1.46	8.24e-04	GO:0044463	cell projection part
1.61	9.57e-04	GO:0016323	basolateral plasma membrane
1.83	1.05e-03	GO:0031253	cell projection membrane
1.33	1.17e-03	GO:0031988	membrane-bounded vesicle
2.19	1.21e-03	GO:0031256	leading edge membrane
1.31	1.89e-03	GO:0031982	vesicle
1.91	2.01e-03	GO:0019898	extrinsic to membrane
1.90	2.84e-03	GO:0019717	synaptosome
1.32	3.39e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
1.60	3.47e-03	GO:0034702	ion channel complex
1.07	4.71e-03	GO:0043231	intracellular membrane-bounded organelle
1.07	4.76e-03	GO:0043227	membrane-bounded organelle
1.39	4.98e-03	GO:0000139	Golgi membrane
1.65	6.16e-03	GO:0043025	neuronal cell body
1.63	8.75e-03	GO:0044297	cell body
1.29	1.17e-02	GO:0031410	cytoplasmic vesicle
3.09	2.42e-02	GO:0032589	neuron projection membrane
1.56	3.00e-02	GO:0030425	dendrite
1.09	3.77e-02	GO:0005634	nucleus

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.10	2.95e-22	GO:0005488	binding
1.18	4.92e-22	GO:0005515	protein binding
1.52	4.80e-14	GO:0001071	nucleic acid binding transcription factor activity
1.52	4.80e-14	GO:0003700	sequence-specific DNA binding transcription factor activity
1.63	2.22e-09	GO:0060589	nucleoside-triphosphatase regulator activity
1.64	3.09e-09	GO:0030695	GTPase regulator activity
1.51	7.54e-09	GO:0043565	sequence-specific DNA binding
1.54	9.84e-09	GO:0004672	protein kinase activity
1.40	6.51e-08	GO:0030528	transcription regulator activity
1.46	1.46e-07	GO:0019899	enzyme binding
1.18	2.49e-07	GO:0046872	metal ion binding
1.45	3.00e-07	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.59	3.82e-07	GO:0019904	protein domain specific binding
1.72	3.96e-07	GO:0005083	small GTPase regulator activity
1.17	7.31e-07	GO:0043169	cation binding
1.17	1.31e-06	GO:0043167	ion binding
1.42	1.43e-06	GO:0016301	kinase activity
1.56	2.51e-06	GO:0004674	protein serine/threonine kinase activity
1.62	1.61e-05	GO:0016563	transcription activator activity
1.87	2.42e-05	GO:0005085	guanyl-nucleotide exchange factor activity
2.10	3.89e-05	GO:0005057	receptor signaling protein activity
1.88	1.05e-04	GO:0022843	voltage-gated cation channel activity
1.34	1.10e-04	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.43	2.50e-04	GO:0008092	cytoskeletal protein binding
1.36	3.03e-04	GO:0042802	identical protein binding
1.49	5.16e-04	GO:0008047	enzyme activator activity
1.60	8.72e-04	GO:0005096	GTPase activator activity
2.02	1.06e-03	GO:0005088	Ras guanyl-nucleotide exchange factor activity
1.67	1.48e-03	GO:0010843	promoter binding
1.18	1.64e-03	GO:0003677	DNA binding
1.61	1.78e-03	GO:0019900	kinase binding
1.65	1.98e-03	GO:0000975	regulatory region DNA binding
1.65	1.98e-03	GO:0001067	regulatory region nucleic acid binding
1.65	1.98e-03	GO:0044212	transcription regulatory region DNA binding
2.06	2.11e-03	GO:0019199	transmembrane receptor protein kinase activity
1.64	6.17e-03	GO:0005244	voltage-gated ion channel activity
1.64	6.17e-03	GO:0022832	voltage-gated channel activity
1.83	6.39e-03	GO:0051020	GTPase binding
1.28	6.90e-03	GO:0030234	enzyme regulator activity
1.17	7.38e-03	GO:0046914	transition metal ion binding
1.27	7.43e-03	GO:0022892	substrate-specific transporter activity
1.18	7.77e-03	GO:0008270	zinc ion binding
1.49	8.54e-03	GO:0016564	transcription repressor activity
1.36	1.00e-02	GO:0008324	cation transmembrane transporter activity
1.74	1.02e-02	GO:0004713	protein tyrosine kinase activity
1.46	1.05e-02	GO:0042578	phosphoric ester hydrolase activity
1.19	1.06e-02	GO:0017076	purine nucleotide binding
1.51	1.42e-02	GO:0005261	cation channel activity
1.47	1.43e-02	GO:0003779	actin binding
1.59	1.48e-02	GO:0019901	protein kinase binding
1.18	1.57e-02	GO:0032553	ribonucleotide binding
1.18	1.57e-02	GO:0032555	purine ribonucleotide binding
2.09	1.77e-02	GO:0004714	transmembrane receptor protein tyrosine kinase activity
2.24	2.03e-02	GO:0004702	receptor signaling protein serine/threonine kinase activity
2.03	2.63e-02	GO:0030165	PDZ domain binding
1.47	2.81e-02	GO:0008134	transcription factor binding
1.83	2.84e-02	GO:0005249	voltage-gated potassium channel activity
1.46	3.09e-02	GO:0022836	gated channel activity
1.27	3.39e-02	GO:0022891	substrate-specific transmembrane transporter activity
1.85	4.36e-02	GO:0003704	specific RNA polymerase II transcription factor activity
1.50	4.46e-02	GO:0003702	RNA polymerase II transcription factor activity
1.70	4.96e-02	GO:0005267	potassium channel activity