Motif ID: HLF.p2

Z-value: 1.400


Transcription factors associated with HLF.p2:

Gene SymbolEntrez IDGene Name
HLF 3131 hepatic leukemia factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HLFchr17_+_533449660.161.8e-02Click!


Activity profile for motif HLF.p2.

activity profile for motif HLF.p2


Sorted Z-values histogram for motif HLF.p2

Sorted Z-values for motif HLF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HLF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_72088507 15.625 NM_001126102
NM_005143
HP

haptoglobin

chr9_+_117085302 15.053 NM_000607
ORM1
orosomucoid 1
chr9_+_111624545 14.958 NM_006687
ACTL7A
actin-like 7A
chr6_+_131894343 14.815 NM_000045
NM_001244438
ARG1

arginase, liver

chr2_+_113885137 14.493 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr9_+_117092068 13.392 NM_000608
ORM2
orosomucoid 2
chr20_+_47895168 13.159 ZNFX1-AS1
ZNFX1 antisense RNA 1 (non-protein coding)
chr3_-_49726081 13.078 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr16_-_55866972 13.049 CES1
carboxylesterase 1
chr3_-_47957475 12.877


chr9_+_36169384 12.832 NM_005893
CCIN
calicin
chr16_-_55867016 12.728 NM_001025194
NM_001025195
NM_001266
CES1


carboxylesterase 1


chr14_-_70263871 12.413 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr14_-_23284617 12.172 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr16_+_72097124 11.528 NM_020995
HPR
haptoglobin-related protein
chr5_-_140012730 11.369 CD14
CD14 molecule
chr19_-_40919270 10.748 NM_020956
NM_181882
PRX

periaxin

chr3_+_186330844 10.392 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr12_+_112856701 10.234 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr5_-_140013034 10.204 NM_000591
CD14
CD14 molecule
chr14_-_23284565 10.059 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_+_45971249 9.981 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr1_-_230849863 9.727 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_+_186383770 9.519 NM_000412
HRG
histidine-rich glycoprotein
chr19_-_41356193 9.478 NM_000762
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr1_+_154377847 9.117 IL6R
interleukin 6 receptor
chr2_+_113885145 9.020 IL1RN
interleukin 1 receptor antagonist
chr8_-_6735438 8.862 NM_005218
DEFB1
defensin, beta 1
chr3_+_133494275 8.736 TF
transferrin
chr5_+_150399980 8.675 NM_002084
GPX3
glutathione peroxidase 3 (plasma)
chr3_-_195306274 8.645 APOD
apolipoprotein D
chr18_-_13726582 8.566 NM_001098801
NM_152352
FAM210A

family with sequence similarity 210, member A

chr1_-_202896315 8.490 KLHL12
kelch-like 12 (Drosophila)
chrY_-_15591799 8.265 UTY
ubiquitously transcribed tetratricopeptide repeat gene, Y-linked
chr12_-_13256572 8.235 NM_001080554
NM_001080555
NM_001206842
GSG1


germ cell associated 1


chr14_+_21423627 8.180 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr19_+_35773409 8.172 NM_021175
HAMP
hepcidin antimicrobial peptide
chr1_+_196621007 8.121 NM_000186
NM_001014975
CFH

complement factor H

chr1_-_230849847 8.023 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_+_186435097 7.941 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr1_-_114429996 7.925 BCL2L15
BCL2-like 15
chr4_+_128802064 7.687 NM_001190801
PLK4
polo-like kinase 4
chr11_-_6462129 7.665 NM_000613
HPX
hemopexin
chr16_+_68057144 7.664 NM_017803
DUS2L
dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
chr1_+_151739130 7.604 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr1_-_202896368 7.597 NM_021633
KLHL12
kelch-like 12 (Drosophila)
chr11_-_14993790 7.550 NM_001033952
NM_001033953
NM_001741
CALCA


calcitonin-related polypeptide alpha


chr12_-_105322056 7.193 NM_032148
SLC41A2
solute carrier family 41, member 2
chr1_+_158801105 6.931 NM_002432
MNDA
myeloid cell nuclear differentiation antigen
chr1_+_152850797 6.915 NM_030663
SMCP
sperm mitochondria-associated cysteine-rich protein
chr3_+_186330859 6.905 AHSG
alpha-2-HS-glycoprotein
chr19_+_41594367 6.900 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr3_-_58200397 6.769 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr9_+_105757592 6.732 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr20_+_16728997 6.604 NM_020157
OTOR
otoraplin
chr8_-_145115565 6.456 NM_017570
OPLAH
5-oxoprolinase (ATP-hydrolysing)
chr13_+_23755059 6.432 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr2_-_73869493 6.260 NM_003960
NAT8
N-acetyltransferase 8 (GCN5-related, putative)
chr9_-_95298251 6.241 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr14_-_23285011 6.165 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr15_+_58430394 6.160 NM_020980
AQP9
aquaporin 9
chr7_+_65958643 6.103


chr14_+_103388992 6.062 NM_030943
AMN
amnionless homolog (mouse)
chr8_+_24298442 6.038 NM_003817
ADAM7
ADAM metallopeptidase domain 7
chr8_-_86253863 6.034 NM_001164830
CA1
carbonic anhydrase I
chr6_-_169653922 6.023 THBS2
thrombospondin 2
chr7_-_31380507 5.989 NM_022728
NEUROD6
neurogenic differentiation 6
chrX_-_15620191 5.967 NM_021804
ACE2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr2_-_114514196 5.961 NM_025181
SLC35F5
solute carrier family 35, member F5
chr19_-_5340700 5.959 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr10_-_52645430 5.857 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr7_-_129592794 5.850 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H

chr12_+_112856756 5.794 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr22_+_24979717 5.673 NM_013430
GGT1
gamma-glutamyltransferase 1
chr2_-_88427535 5.398 NM_001443
FABP1
fatty acid binding protein 1, liver
chr2_+_169926084 5.366 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr17_-_34328530 5.311 CCL14-CCL15
CCL15
CCL14-CCL15 readthrough
chemokine (C-C motif) ligand 15
chr4_+_100485239 5.285 NM_000253
MTTP
microsomal triglyceride transfer protein
chr19_+_45504686 5.239 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr19_+_859658 5.201 NM_001928
CFD
complement factor D (adipsin)
chr19_-_6459735 5.199 NM_024103
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr6_+_144612872 5.186 NM_007124
UTRN
utrophin
chr6_+_27833033 5.068 NM_003511
HIST1H2AI
HIST1H2AL
histone cluster 1, H2ai
histone cluster 1, H2al
chr1_+_241695433 5.058 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_-_713985 5.040 LOC100288069
general transcription factor IIi pseudogene
chr13_-_46626845 4.997 NM_015070
ZC3H13
zinc finger CCCH-type containing 13
chr6_+_26204779 4.992 NM_003545
HIST1H4E
histone cluster 1, H4e
chr16_+_30484049 4.990 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr12_-_28124915 4.985 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr19_-_46088074 4.942 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr19_-_41388656 4.881 NM_000764
NM_030589
CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr3_+_186330711 4.766 AHSG
alpha-2-HS-glycoprotein
chr14_-_25045428 4.755 NM_001911
CTSG
cathepsin G
chr12_-_4754275 4.719 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr4_+_74269971 4.710 NM_000477
ALB
albumin
chr13_-_46679143 4.677 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chr2_-_113594325 4.666 NM_000576
IL1B
interleukin 1, beta
chr19_-_46088021 4.664 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr6_-_132032156 4.646 NM_001145659
CTAGE9
CTAGE family, member 9
chr17_-_34524054 4.633 NM_001001437
NM_021006
CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chrX_-_15332680 4.623 NM_001012428
ASB11
ankyrin repeat and SOCS box containing 11
chr6_+_31895201 4.565 NM_000063
NM_001145903
C2

complement component 2

chr4_+_128802015 4.557 NM_001190799
NM_014264
PLK4

polo-like kinase 4

chrX_+_41306686 4.534 NM_022567
NYX
nyctalopin
chr12_-_8043743 4.530 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr20_-_44600939 4.504 ZNF335
zinc finger protein 335
chr16_-_4588738 4.489 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr17_+_34431219 4.488 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr5_-_147162251 4.469 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr11_-_62457001 4.438 LRRN4CL
LRRN4 C-terminal like
chr6_+_101846668 4.425 GRIK2
glutamate receptor, ionotropic, kainate 2
chr10_-_82049178 4.425 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr4_-_185747183 4.406 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chr6_-_90024936 4.395 NM_002043
GABRR2
gamma-aminobutyric acid (GABA) receptor, rho 2
chr11_+_28129797 4.388 NM_001113528
NM_152636
METTL15

methyltransferase like 15

chr10_-_95360959 4.343 NM_006744
RBP4
retinol binding protein 4, plasma
chr12_-_53074172 4.325 NM_006121
KRT1
keratin 1
chr17_-_71308118 4.317 NM_012121
CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
chr2_+_70142303 4.295 MXD1
MAX dimerization protein 1
chr14_+_88851987 4.287 NM_001040428
NM_018418
SPATA7

spermatogenesis associated 7

chr10_+_22634373 4.213 NM_001253854
NM_001253855
NM_012443
NM_172242
SPAG6



sperm associated antigen 6



chr3_+_122044010 4.160 NM_005213
CSTA
cystatin A (stefin A)
chr2_-_110962539 4.110 NPHP1
nephronophthisis 1 (juvenile)
chr1_+_196857143 4.088 NM_001201550
NM_001201551
NM_006684
CFHR4


complement factor H-related 4


chr5_+_150400132 4.087 GPX3
glutathione peroxidase 3 (plasma)
chr19_+_49259343 4.084 NM_019113
FGF21
fibroblast growth factor 21
chr6_+_31895401 4.082 C2
complement component 2
chrY_-_297689 4.072 NM_013239
PPP2R3B
protein phosphatase 2, regulatory subunit B'', beta
chr3_+_128598471 4.071 ACAD9
acyl-CoA dehydrogenase family, member 9
chr1_+_158901336 4.065 NM_152501
NM_198928
NM_198929
NM_198930
PYHIN1



pyrin and HIN domain family, member 1



chr17_-_34328607 4.058 CCL14-CCL15
CCL14-CCL15 readthrough
chr16_+_30483959 4.043 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chr10_+_5238756 4.019 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr20_+_23471765 4.009 NM_005492
CST8
cystatin 8 (cystatin-related epididymal specific)
chr12_-_117319231 4.003 NM_003806
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr1_-_62785067 3.989 NM_181712
KANK4
KN motif and ankyrin repeat domains 4
chr7_+_143880547 3.974 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr12_+_21679190 3.952 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr5_-_58882274 3.951 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr19_+_45417920 3.948 NM_001645
APOC1
apolipoprotein C-I
chr16_+_31128973 3.941 NM_032188
NM_182958
KAT8

K(lysine) acetyltransferase 8

chr19_-_460995 3.856 NM_012435
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr9_-_104198045 3.821 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chrX_+_152224862 3.820 PNMA3
paraneoplastic antigen MA3
chr19_-_2042022 3.809 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr19_+_859673 3.764 CFD
complement factor D (adipsin)
chr3_-_120400957 3.733 HGD
homogentisate 1,2-dioxygenase
chrX_+_15518899 3.728 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr6_-_32339648 3.710 NM_006781
C6orf10
chromosome 6 open reading frame 10
chr14_+_21359542 3.693 NM_002935
RNASE3
ribonuclease, RNase A family, 3
chr22_+_25003610 3.686 NM_001032365
GGT1
gamma-glutamyltransferase 1
chr11_-_18258383 3.659 NM_006512
SAA4
serum amyloid A4, constitutive
chr1_-_173174611 3.594 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr11_+_12695851 3.575 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr2_-_31637553 3.551 XDH
xanthine dehydrogenase
chr22_-_29457793 3.544 NM_015370
C22orf31
chromosome 22 open reading frame 31
chr11_-_5275904 3.527 NM_000184
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr19_-_46088084 3.496 NM_001017989
NM_025136
OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr19_+_41430123 3.481 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr17_-_34329083 3.477 NM_032965
CCL15
chemokine (C-C motif) ligand 15
chr14_+_60715950 3.476 NM_021003
NM_177951
PPM1A

protein phosphatase, Mg2+/Mn2+ dependent, 1A

chr7_-_143966380 3.474 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chrX_-_118699318 3.457 NM_001170569
CXorf56
chromosome X open reading frame 56
chr7_-_129592711 3.446 NM_001202498
UBE2H
ubiquitin-conjugating enzyme E2H
chr8_+_40010986 3.443 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr8_+_27179918 3.437 NM_004103
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr5_-_53606387 3.434 NM_019087
ARL15
ADP-ribosylation factor-like 15
chr5_-_160279045 3.404 NM_025153
ATP10B
ATPase, class V, type 10B
chr9_-_77503009 3.381 NM_017662
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chrX_-_138724851 3.373 NM_001171877
NM_001171878
NM_001171879
NM_005369
MCF2



MCF.2 cell line derived transforming sequence



chr17_+_11501747 3.353 NM_001372
DNAH9
dynein, axonemal, heavy chain 9
chr16_-_68057098 3.349 DDX28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr20_+_42187634 3.282 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr14_+_24563369 3.277 NM_001018073
NM_004563
PCK2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

chr1_+_168148215 3.267 TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr20_-_43883183 3.256 NM_003064
SLPI
secretory leukocyte peptidase inhibitor
chr8_-_143999255 3.254 NM_000498
CYP11B2
cytochrome P450, family 11, subfamily B, polypeptide 2
chr10_+_86004808 3.246 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr16_-_86588680 3.229 NM_001159380
NM_001159377
NM_001159378
NM_001159379
NM_022764
MTHFSD




methenyltetrahydrofolate synthetase domain containing




chr11_+_113775517 3.229 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr4_-_185747051 3.193 ACSL1
acyl-CoA synthetase long-chain family member 1
chr7_-_37956515 3.167 NM_003014
SFRP4
secreted frizzled-related protein 4
chr21_-_45079327 3.138 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr1_-_153348057 3.138 NM_005621
S100A12
S100 calcium binding protein A12
chr12_+_58138663 3.134 NM_005981
TSPAN31
tetraspanin 31
chr12_-_52845862 3.130 NM_005555
KRT6B
keratin 6B
chr4_-_76928601 3.125 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr19_+_13056607 3.108 NM_005053
RAD23A
RAD23 homolog A (S. cerevisiae)
chr4_+_108911008 3.105 HADH
hydroxyacyl-CoA dehydrogenase
chr15_+_93443418 3.068 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr17_-_4607414 3.045 PELP1
proline, glutamate and leucine rich protein 1
chr4_+_87968191 2.966 AFF1
AF4/FMR2 family, member 1
chr11_-_102576444 2.965 NM_022122
MMP27
matrix metallopeptidase 27
chr1_+_196788860 2.920 NM_002113
CFHR1
complement factor H-related 1
chr16_-_68057120 2.915 DDX28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr5_+_42425093 2.902 NM_001242401
GHR
growth hormone receptor
chr14_+_29241989 2.898 C14orf23
chromosome 14 open reading frame 23
chr1_-_230850335 2.882 NM_000029
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr7_+_143268872 2.870 NM_001008747
CTAGE6P
CTAGE15P
CTAGE family, member 6, pseudogene
CTAGE family, member 15, pseudogene
chr11_+_61717355 2.859 NM_001139443
NM_004183
BEST1

bestrophin 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.95 3.05e-09 GO:0006954 inflammatory response
2.57 2.87e-08 GO:0006955 immune response
2.40 3.61e-08 GO:0009611 response to wounding
2.37 7.69e-07 GO:0006952 defense response
1.35 2.65e-06 GO:0050896 response to stimulus
18.56 2.91e-05 GO:0060600 dichotomous subdivision of an epithelial terminal unit
1.37 4.30e-05 GO:0032501 multicellular organismal process
3.23 5.01e-05 GO:0055065 metal ion homeostasis
1.66 7.23e-05 GO:0065008 regulation of biological quality
21.88 7.75e-05 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
19.45 2.26e-04 GO:0048880 sensory system development
19.45 2.26e-04 GO:0048892 lateral line nerve development
19.45 2.26e-04 GO:0048895 lateral line nerve glial cell differentiation
19.45 2.26e-04 GO:0048925 lateral line system development
19.45 2.26e-04 GO:0048937 lateral line nerve glial cell development
19.45 2.26e-04 GO:0050935 iridophore differentiation
3.11 3.22e-04 GO:0006875 cellular metal ion homeostasis
2.52 4.36e-04 GO:0050801 ion homeostasis
13.61 5.03e-04 GO:0048485 sympathetic nervous system development
1.56 9.10e-04 GO:0006950 response to stress
2.50 1.18e-03 GO:0055082 cellular chemical homeostasis
2.77 1.41e-03 GO:0055080 cation homeostasis
2.51 1.50e-03 GO:0006873 cellular ion homeostasis
1.81 1.98e-03 GO:0002376 immune system process
2.82 2.26e-03 GO:0030003 cellular cation homeostasis
14.58 2.28e-03 GO:0048846 axon extension involved in axon guidance
14.58 2.28e-03 GO:0090184 positive regulation of kidney development
1.55 3.25e-03 GO:0042221 response to chemical stimulus
1.90 3.46e-03 GO:0009605 response to external stimulus
1.77 3.69e-03 GO:0051239 regulation of multicellular organismal process
8.64 4.18e-03 GO:0048483 autonomic nervous system development
2.00 4.20e-03 GO:0048584 positive regulation of response to stimulus
3.18 5.53e-03 GO:0072507 divalent inorganic cation homeostasis
2.14 7.07e-03 GO:0048878 chemical homeostasis
11.67 1.13e-02 GO:0030513 positive regulation of BMP signaling pathway
11.67 1.13e-02 GO:0048484 enteric nervous system development
3.14 1.14e-02 GO:0055074 calcium ion homeostasis
3.14 1.14e-02 GO:0072503 cellular divalent inorganic cation homeostasis
3.10 1.34e-02 GO:0003013 circulatory system process
3.10 1.34e-02 GO:0008015 blood circulation
8.88 1.51e-02 GO:0090183 regulation of kidney development
2.19 2.31e-02 GO:0006935 chemotaxis
2.19 2.31e-02 GO:0042330 taxis
2.49 2.34e-02 GO:0051240 positive regulation of multicellular organismal process
3.08 2.52e-02 GO:0006874 cellular calcium ion homeostasis
8.17 2.79e-02 GO:0018149 peptide cross-linking
2.13 3.20e-02 GO:0019725 cellular homeostasis
6.48 4.35e-02 GO:0021675 nerve development
2.69 4.78e-02 GO:0009617 response to bacterium

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.62 8.91e-11 GO:0005615 extracellular space
1.87 8.03e-10 GO:0005576 extracellular region
2.29 1.96e-09 GO:0044421 extracellular region part
4.61 3.27e-02 GO:0031091 platelet alpha granule
1.63 3.82e-02 GO:0000267 cell fraction
4.97 4.53e-02 GO:0031093 platelet alpha granule lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
6.86 4.38e-05 GO:0042379 chemokine receptor binding
6.98 1.25e-04 GO:0008009 chemokine activity
3.05 1.04e-02 GO:0001664 G-protein-coupled receptor binding