Motif ID: IKZF1.p2

Z-value: 1.601


Transcription factors associated with IKZF1.p2:

Gene SymbolEntrez IDGene Name
IKZF1 10320 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
IKZF1chr7_+_50344255-0.393.4e-09Click!


Activity profile for motif IKZF1.p2.

activity profile for motif IKZF1.p2


Sorted Z-values histogram for motif IKZF1.p2

Sorted Z-values for motif IKZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_74728963 12.631 MBP
myelin basic protein
chr18_-_74729049 12.598 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr9_-_21994379 11.795 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr17_-_56618178 11.786 NM_001198713
SEPT4
septin 4
chr9_-_21994414 11.107 NM_058195
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr3_-_149688638 9.586 NM_002628
NM_053024
PFN2

profilin 2

chr16_+_29690464 9.036 QPRT
quinolinate phosphoribosyltransferase
chr4_-_176733413 8.984 GPM6A
glycoprotein M6A
chr2_+_17721806 8.950 NM_003385
VSNL1
visinin-like 1
chr9_-_21994329 8.949 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr19_-_10697907 8.807 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr16_+_56659679 8.680 MT1E
metallothionein 1E
chr16_+_56659584 8.547 NM_175617
MT1E
metallothionein 1E
chr2_+_17721983 8.446 VSNL1
visinin-like 1
chr4_-_176734181 8.337 NM_201591
GPM6A
glycoprotein M6A
chr1_+_6845381 7.592 NM_001195563
NM_001242701
NM_015215
CAMTA1


calmodulin binding transcription activator 1


chr4_-_176733901 7.415 GPM6A
glycoprotein M6A
chr16_+_23690234 7.136 PLK1
polo-like kinase 1
chr8_+_145065366 7.101 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr15_+_41136178 7.014 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr2_+_47596286 6.932 NM_002354
EPCAM
epithelial cell adhesion molecule
chr9_+_130911731 6.931 NM_005564
LCN2
lipocalin 2
chr16_+_29690328 6.881 NM_014298
QPRT
quinolinate phosphoribosyltransferase
chr4_-_120987890 6.680 NM_002358
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr12_+_48499655 6.571 NM_001166686
PFKM
phosphofructokinase, muscle
chr12_+_52627007 6.470 KRT7
keratin 7
chr11_+_62649160 6.457 SLC3A2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr12_+_52626953 6.394 NM_005556
KRT7
keratin 7
chr16_+_23690212 6.381 PLK1
polo-like kinase 1
chr1_+_33352071 6.050 NM_002143
HPCA
hippocalcin
chr7_-_148581359 6.031 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr3_+_52232174 5.996 ALAS1
aminolevulinate, delta-, synthase 1
chr3_+_52232076 5.973 NM_199166
NM_000688
ALAS1

aminolevulinate, delta-, synthase 1

chr15_-_72522062 5.910 NM_001206799
PKM2
pyruvate kinase, muscle
chr7_-_148581403 5.862 NM_001203247
NM_001203248
NM_004456
NM_152998
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr8_+_48873533 5.847 MCM4
minichromosome maintenance complex component 4
chr19_-_42498221 5.798 ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr8_-_121457625 5.774 NM_014078
MRPL13
mitochondrial ribosomal protein L13
chr6_+_34204928 5.755 HMGA1
high mobility group AT-hook 1
chr21_+_41239346 5.701 NM_006198
PCP4
Purkinje cell protein 4
chrX_-_53310748 5.686 NM_001243197
NM_015075
IQSEC2

IQ motif and Sec7 domain 2

chr20_+_56136136 5.679 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr8_+_37887990 5.648 NM_004095
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
chr12_-_53298765 5.562 NM_002273
KRT8
keratin 8
chr3_+_52232179 5.472 ALAS1
aminolevulinate, delta-, synthase 1
chr20_-_3149070 5.348 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr3_-_58563070 5.336 FAM107A
family with sequence similarity 107, member A
chr11_+_73357222 5.315 NM_001130033
NM_021200
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr7_-_148581377 5.301 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr7_-_148581379 5.284 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr19_-_42498320 5.240 NM_152296
ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr10_+_105036783 5.119 NM_032727
INA
internexin neuronal intermediate filament protein, alpha
chr6_-_38670922 5.085 NM_006708
GLO1
glyoxalase I
chr12_-_49259549 5.069 NM_014470
RND1
Rho family GTPase 1
chr1_-_43637788 5.045 EBNA1BP2
EBNA1 binding protein 2
chrX_-_71792610 5.038 HDAC8
histone deacetylase 8
chr11_+_62475165 4.990 GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr13_-_111213865 4.983 NM_017817
RAB20
RAB20, member RAS oncogene family
chr7_-_148581297 4.891 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr1_-_8931634 4.856 NM_001201483
ENO1
enolase 1, (alpha)
chr6_-_33168448 4.701 RXRB
retinoid X receptor, beta
chr1_-_209825797 4.679 NM_000228
LAMB3
laminin, beta 3
chr9_+_17578952 4.612 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr17_+_52978022 4.605 NM_005486
TOM1L1
target of myb1 (chicken)-like 1
chr1_+_155853546 4.572 SYT11
synaptotagmin XI
chr11_+_71903172 4.566 NM_016729
FOLR1
folate receptor 1 (adult)
chr8_-_121457387 4.498 MRPL13
mitochondrial ribosomal protein L13
chr2_-_224467095 4.443 SCG2
secretogranin II
chr1_-_183274008 4.417 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr17_+_44068828 4.405 MAPT
microtubule-associated protein tau
chr2_-_224467142 4.371 NM_003469
SCG2
secretogranin II
chr8_-_121457333 4.363 MRPL13
mitochondrial ribosomal protein L13
chr16_+_56703725 4.351 NM_005951
MT1H
metallothionein 1H
chr16_+_23690160 4.309 PLK1
polo-like kinase 1
chr19_+_38755097 4.254 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr17_-_42992852 4.163 NM_001131019
NM_001242376
NM_002055
GFAP


glial fibrillary acidic protein


chr7_-_100888367 4.119 NM_016068
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr16_+_23690191 4.083 NM_005030
PLK1
polo-like kinase 1
chr20_+_44441334 4.061 UBE2C
ubiquitin-conjugating enzyme E2C
chr11_+_60691911 4.003 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr5_-_122372320 3.952 PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr8_+_22224786 3.899 SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr16_+_89989686 3.899 NM_006086
TUBB3
tubulin, beta 3 class III
chr8_-_63951353 3.884 GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr12_-_56881901 3.880 NM_013267
GLS2
glutaminase 2 (liver, mitochondrial)
chr12_-_6960406 3.879 NM_031299
CDCA3
cell division cycle associated 3
chr7_-_99698916 3.871 MCM7
minichromosome maintenance complex component 7
chr12_+_66218141 3.792 NM_003483
NM_003484
HMGA2

high mobility group AT-hook 2

chr19_+_496453 3.790 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr22_+_38201113 3.784 NM_005318
H1F0
H1 histone family, member 0
chr17_-_7517849 3.774 FXR2
fragile X mental retardation, autosomal homolog 2
chr7_-_99698278 3.756 NM_182776
MCM7
minichromosome maintenance complex component 7
chr1_-_43637969 3.754 NM_006824
NM_001159936
EBNA1BP2

EBNA1 binding protein 2

chr19_+_35739282 3.754 LSR
lipolysis stimulated lipoprotein receptor
chr4_-_155533850 3.744 FGG
fibrinogen gamma chain
chr8_+_143808593 3.744 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr8_-_63951609 3.673 NM_003878
GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr7_-_100888285 3.653 FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr1_-_209825673 3.616 NM_001127641
LAMB3
laminin, beta 3
chr1_+_32042085 3.615 NM_001204414
NM_022164
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr19_+_19322763 3.588 NM_004386
NCAN
neurocan
chr8_-_99129385 3.579 NM_005836
HRSP12
heat-responsive protein 12
chr19_+_38755422 3.566 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chrX_-_102941582 3.554 NM_001142418
NM_001142423
NM_001142424
NM_001142425
NM_001142426
NM_001142429
NM_001142430
NM_012286
MORF4L2







mortality factor 4 like 2







chrX_+_47078053 3.548 NM_006201
CDK16
cyclin-dependent kinase 16
chr4_-_155533800 3.544 FGG
fibrinogen gamma chain
chr4_-_155533882 3.505 NM_000509
NM_021870
FGG

fibrinogen gamma chain

chr8_+_22224758 3.462 NM_001128431
NM_001135154
NM_015359
SLC39A14


solute carrier family 39 (zinc transporter), member 14


chr1_+_32042122 3.381 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr2_-_224467049 3.361 SCG2
secretogranin II
chr6_-_42981656 3.353 MEA1
male-enhanced antigen 1
chr1_-_85930733 3.352 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr19_+_33182689 3.337 NM_001105570
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr10_-_15413054 3.332 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr11_-_62475060 3.318 NM_001122955
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_-_6453773 3.317 NM_007274
ACOT7
acyl-CoA thioesterase 7
chr5_-_122372413 3.315 NM_000943
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr5_-_133340823 3.307 NM_003374
VDAC1
voltage-dependent anion channel 1
chr17_-_4843204 3.288 NM_001165417
NM_001165418
NM_003562
SLC25A11


solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11


chr16_-_19533285 3.260 NM_016641
GDE1
glycerophosphodiester phosphodiesterase 1
chr6_-_31514393 3.257 ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr4_-_155533757 3.251 FGG
fibrinogen gamma chain
chr1_+_32042125 3.234 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr20_-_33872289 3.232 EIF6
eukaryotic translation initiation factor 6
chr11_-_35440514 3.215 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_+_165797060 3.200 UCK2
uridine-cytidine kinase 2
chr3_+_127317271 3.199 MCM2
minichromosome maintenance complex component 2
chr17_-_57784756 3.188 NM_016077
PTRH2
peptidyl-tRNA hydrolase 2
chr3_+_127317274 3.177 MCM2
minichromosome maintenance complex component 2
chr5_+_176875325 3.176 NM_001174102
PRR7
proline rich 7 (synaptic)
chr1_-_43637958 3.151 EBNA1BP2
EBNA1 binding protein 2
chr11_-_18270167 3.145 NM_001199744
NM_001127380
NM_030754
SAA2-SAA4
SAA2

SAA2-SAA4 readthrough
serum amyloid A2

chr19_+_38755238 3.138 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr1_+_151372009 3.138 NM_002796
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr1_-_85930610 3.134 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr9_-_35103144 3.129 NM_013442
STOML2
stomatin (EPB72)-like 2
chr22_+_38201232 3.074 H1F0
H1 histone family, member 0
chr20_+_44441247 3.000 NM_007019
NM_181799
NM_181800
NM_181802
NM_181803
UBE2C




ubiquitin-conjugating enzyme E2C




chr1_+_153600859 2.990 NM_006271
S100A1
S100 calcium binding protein A1
chr17_+_38137053 2.990 NM_002809
PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr5_+_36606667 2.990 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_-_1303402 2.980 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr11_+_18287807 2.977 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chrX_+_47077426 2.971 NM_033018
CDK16
cyclin-dependent kinase 16
chr17_+_48712115 2.969 NM_001144070
NM_003786
ABCC3

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

chr14_+_66975205 2.969 GPHN
gephyrin
chr3_+_35722428 2.965 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr5_+_140186658 2.948 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr16_-_87903028 2.935 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr2_-_238499317 2.927 RAB17
RAB17, member RAS oncogene family
chr6_+_125474800 2.919 NM_001003396
NM_001003397
NM_003287
TPD52L1


tumor protein D52-like 1


chr1_+_164528586 2.911 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr16_+_30064470 2.900 ALDOA
aldolase A, fructose-bisphosphate
chr7_+_99686561 2.899 NM_006833
COPS6
COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
chr14_+_101295409 2.898 MEG3
maternally expressed 3 (non-protein coding)
chr3_-_127541160 2.887 NM_007283
MGLL
monoglyceride lipase
chr1_-_201368434 2.875 LAD1
ladinin 1
chr9_-_35103048 2.871 STOML2
stomatin (EPB72)-like 2
chr17_+_25799024 2.868 NM_014238
KSR1
kinase suppressor of ras 1
chr1_+_77747602 2.854 NM_174858
AK5
adenylate kinase 5
chr1_-_202612580 2.839 NM_001136504
SYT2
synaptotagmin II
chr19_-_51869632 2.826 NM_001985
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr16_+_71392615 2.814 NM_001740
NM_007088
CALB2

calbindin 2

chr3_-_58563490 2.813 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr17_+_48172508 2.806 NM_001199900
NM_002611
NM_001199899
PDK2


pyruvate dehydrogenase kinase, isozyme 2


chr9_-_35103089 2.806 STOML2
stomatin (EPB72)-like 2
chr1_+_203020310 2.803 NM_015053
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr17_+_38137115 2.801 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr4_-_176923480 2.792 GPM6A
glycoprotein M6A
chr4_-_40631846 2.787 NM_001098634
RBM47
RNA binding motif protein 47
chr8_+_105352050 2.772 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr1_+_155099935 2.764 EFNA1
ephrin-A1
chr2_-_238499713 2.760 NM_022449
RAB17
RAB17, member RAS oncogene family
chr3_+_46619075 2.729 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr17_+_38137106 2.723 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr11_+_62475113 2.703 NM_012202
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr5_-_125930604 2.700 NM_001182
NM_001201377
NM_001202404
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chr17_+_38137081 2.689 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr21_-_34960937 2.672 NM_017613
DONSON
downstream neighbor of SON
chr16_+_71392637 2.670 CALB2
calbindin 2
chr16_+_23690190 2.667 PLK1
polo-like kinase 1
chr3_+_62305395 2.661 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr1_+_15250578 2.661 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr20_+_34742656 2.659 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr19_-_10514242 2.658 NM_007065
CDC37
cell division cycle 37 homolog (S. cerevisiae)
chr2_+_233498206 2.655 NM_025202
EFHD1
EF-hand domain family, member D1
chr11_+_71900958 2.652 NM_000802
FOLR1
folate receptor 1 (adult)
chr5_-_131563481 2.637 NM_001017974
NM_001142598
NM_001142599
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr16_-_70719854 2.620 NM_138383
MTSS1L
metastasis suppressor 1-like
chr7_+_150756645 2.609 NM_003040
SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr11_+_66247878 2.603 NM_005700
NM_130443
DPP3

dipeptidyl-peptidase 3

chr11_+_64879294 2.596 NM_003273
TM7SF2
transmembrane 7 superfamily member 2
chr19_-_10514154 2.595 CDC37
cell division cycle 37 homolog (S. cerevisiae)
chr4_-_56412968 2.581 NM_004898
CLOCK
clock homolog (mouse)
chr1_+_32043745 2.574 NM_001204415
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr7_+_99686609 2.569 COPS6
COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
chr11_+_66247905 2.563 DPP3
dipeptidyl-peptidase 3
chr7_+_150756716 2.550 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr6_+_42981840 2.538 NM_057161
KLHDC3
kelch domain containing 3
chrX_-_72434656 2.526 NAP1L2
nucleosome assembly protein 1-like 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.22 2.69e-31 GO:0009987 cellular process
1.43 2.93e-15 GO:0023052 signaling
1.38 1.63e-13 GO:0051716 cellular response to stimulus
1.23 2.30e-13 GO:0065007 biological regulation
1.23 7.43e-11 GO:0050794 regulation of cellular process
1.22 3.09e-10 GO:0050789 regulation of biological process
1.38 4.16e-10 GO:0007165 signal transduction
1.25 4.43e-10 GO:0044237 cellular metabolic process
1.61 2.58e-09 GO:0007399 nervous system development
1.24 9.75e-09 GO:0050896 response to stimulus
1.21 1.05e-08 GO:0008152 metabolic process
1.38 1.08e-07 GO:0048731 system development
1.36 1.21e-07 GO:0048856 anatomical structure development
1.22 1.78e-07 GO:0044238 primary metabolic process
1.33 7.02e-07 GO:0006807 nitrogen compound metabolic process
1.34 1.18e-06 GO:0034641 cellular nitrogen compound metabolic process
1.42 1.53e-06 GO:0048523 negative regulation of cellular process
1.40 1.77e-06 GO:0048519 negative regulation of biological process
1.38 2.99e-06 GO:0048522 positive regulation of cellular process
1.41 4.73e-06 GO:0065008 regulation of biological quality
1.28 7.33e-06 GO:0032502 developmental process
1.43 2.20e-05 GO:0044281 small molecule metabolic process
1.34 2.30e-05 GO:0048518 positive regulation of biological process
1.70 2.49e-05 GO:0007267 cell-cell signaling
1.29 3.07e-05 GO:0007275 multicellular organismal development
1.65 8.25e-05 GO:0044093 positive regulation of molecular function
1.36 8.67e-05 GO:0042221 response to chemical stimulus
1.67 4.06e-04 GO:0043085 positive regulation of catalytic activity
1.59 4.55e-04 GO:0042592 homeostatic process
1.53 8.22e-04 GO:0007154 cell communication
1.30 8.56e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 1.13e-03 GO:0006950 response to stress
1.58 1.18e-03 GO:0033554 cellular response to stress
1.53 1.27e-03 GO:0009605 response to external stimulus
1.77 1.45e-03 GO:0019226 transmission of nerve impulse
1.77 1.45e-03 GO:0035637 multicellular organismal signaling
1.19 1.48e-03 GO:0032501 multicellular organismal process
1.25 1.48e-03 GO:0071840 cellular component organization or biogenesis
1.25 3.16e-03 GO:0016043 cellular component organization
1.30 3.37e-03 GO:0044249 cellular biosynthetic process
1.76 3.74e-03 GO:0050801 ion homeostasis
1.53 3.93e-03 GO:0055114 oxidation-reduction process
1.78 4.23e-03 GO:0007268 synaptic transmission
1.39 6.93e-03 GO:0065009 regulation of molecular function
1.70 8.18e-03 GO:0032990 cell part morphogenesis
1.74 1.05e-02 GO:0055082 cellular chemical homeostasis
1.40 1.08e-02 GO:0035556 intracellular signal transduction
2.52 1.14e-02 GO:0031570 DNA integrity checkpoint
1.75 1.18e-02 GO:0006873 cellular ion homeostasis
2.39 1.18e-02 GO:0007005 mitochondrion organization
1.50 1.24e-02 GO:0022008 neurogenesis
1.63 1.26e-02 GO:0006259 DNA metabolic process
1.55 1.54e-02 GO:0007155 cell adhesion
1.55 1.54e-02 GO:0022610 biological adhesion
1.28 1.62e-02 GO:0009058 biosynthetic process
1.33 1.90e-02 GO:0007166 cell surface receptor linked signaling pathway
1.26 2.05e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.60 2.12e-02 GO:0048878 chemical homeostasis
1.67 2.12e-02 GO:0048858 cell projection morphogenesis
1.67 2.29e-02 GO:0044283 small molecule biosynthetic process
1.45 2.36e-02 GO:0042981 regulation of apoptosis
2.04 2.47e-02 GO:0000075 cell cycle checkpoint
1.49 2.71e-02 GO:0008219 cell death
2.01 2.80e-02 GO:0071156 regulation of cell cycle arrest
1.41 2.88e-02 GO:0050790 regulation of catalytic activity
2.49 3.07e-02 GO:0000077 DNA damage checkpoint
1.48 3.44e-02 GO:0016265 death
1.63 3.50e-02 GO:0019725 cellular homeostasis
1.44 3.63e-02 GO:0043067 regulation of programmed cell death
1.58 3.73e-02 GO:0051726 regulation of cell cycle
1.48 4.03e-02 GO:0048699 generation of neurons
1.26 4.74e-02 GO:0071842 cellular component organization at cellular level
1.54 4.88e-02 GO:0030182 neuron differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 9.81e-10 GO:0005737 cytoplasm
1.24 1.33e-09 GO:0044444 cytoplasmic part
1.42 7.17e-08 GO:0044459 plasma membrane part
1.10 1.37e-06 GO:0044424 intracellular part
1.09 1.85e-05 GO:0005622 intracellular
1.42 3.89e-04 GO:0005739 mitochondrion
1.61 4.35e-04 GO:0044429 mitochondrial part
1.17 4.65e-04 GO:0044422 organelle part
1.17 6.56e-04 GO:0044446 intracellular organelle part
1.78 1.16e-03 GO:0043005 neuron projection
1.50 1.53e-03 GO:0042995 cell projection
1.69 3.03e-03 GO:0005740 mitochondrial envelope
1.27 5.06e-03 GO:0031974 membrane-enclosed lumen
1.23 6.84e-03 GO:0043234 protein complex
1.70 7.01e-03 GO:0045202 synapse
2.09 7.54e-03 GO:0044297 cell body
1.67 8.17e-03 GO:0031966 mitochondrial membrane
1.27 8.44e-03 GO:0070013 intracellular organelle lumen
1.40 9.06e-03 GO:0000267 cell fraction
1.56 9.59e-03 GO:0030054 cell junction
2.09 9.66e-03 GO:0043025 neuronal cell body
1.37 1.09e-02 GO:0031226 intrinsic to plasma membrane
1.26 1.40e-02 GO:0043233 organelle lumen
1.10 1.44e-02 GO:0043231 intracellular membrane-bounded organelle
1.04 1.64e-02 GO:0044464 cell part
1.04 1.69e-02 GO:0005623 cell
1.10 1.75e-02 GO:0043227 membrane-bounded organelle
1.09 1.79e-02 GO:0043226 organelle
1.09 1.97e-02 GO:0043229 intracellular organelle
1.27 2.39e-02 GO:0005829 cytosol
1.76 2.60e-02 GO:0044456 synapse part
1.74 3.23e-02 GO:0005743 mitochondrial inner membrane
1.95 3.71e-02 GO:0030425 dendrite
1.34 4.24e-02 GO:0005887 integral to plasma membrane
1.69 4.51e-02 GO:0019866 organelle inner membrane
1.96 4.84e-02 GO:0030424 axon

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.25 3.87e-15 GO:0005515 protein binding
1.12 3.31e-10 GO:0005488 binding
1.52 6.31e-03 GO:0019899 enzyme binding
1.50 2.04e-02 GO:0016491 oxidoreductase activity
2.72 3.31e-02 GO:0005200 structural constituent of cytoskeleton