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• Activity deltas table
• Regulatory interactions
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Motif ID: KLF12.p2

Z-value: 4.372

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_139871954	89.293	NM_000954	PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr12_+_79258517	82.728		SYT1	synaptotagmin I
chr12_+_79258588	74.338		SYT1	synaptotagmin I
chr12_+_79258448	68.987	NM_005639	SYT1	synaptotagmin I
chr2_+_203499819	67.296	NM_173511	FAM117B	family with sequence similarity 117, member B
chr7_+_64498643	58.727		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr1_+_6845381	52.896	NM_001195563 NM_001242701 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr21_-_48024985	50.461	NM_006272	S100B	S100 calcium binding protein B
chr9_+_139872014	50.002		PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr10_-_32636134	49.588		EPC1	enhancer of polycomb homolog 1 (Drosophila)
chr5_+_175792444	48.829	NM_173664	ARL10	ADP-ribosylation factor-like 10
chr17_+_1665342	48.635		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_1665281	47.628		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_1665306	47.019		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr9_-_133454818	44.648		LOC100272217	uncharacterized LOC100272217
chr5_+_137801166	43.910		EGR1	early growth response 1
chr11_+_62475165	43.431		GNG3	guanine nucleotide binding protein (G protein), gamma 3
chr17_+_38119225	43.062	NM_178171	GSDMA	gasdermin A
chr8_-_27115935	42.977		STMN4	stathmin-like 4
chr5_+_137801178	42.681	NM_001964	EGR1	early growth response 1
chr15_+_84115979	41.014	NM_003027	SH3GL3	SH3-domain GRB2-like 3
chr16_+_67198678	39.057		HSF4	heat shock transcription factor 4
chr8_+_80523339	39.033		STMN2	stathmin-like 2
chr8_+_80523376	39.011		STMN2	stathmin-like 2
chr8_+_80523351	38.747		STMN2	stathmin-like 2
chr16_-_31085073	37.451		ZNF668	zinc finger protein 668
chr1_+_159175048	37.211	NM_001122951	DARC	Duffy blood group, chemokine receptor
chr8_+_80523304	37.191		STMN2	stathmin-like 2
chr18_-_74691951	35.827		MBP	myelin basic protein
chr17_+_1665233	35.026	NM_002615	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_-_23821423	34.097	NM_020372	SLC22A17	solute carrier family 22, member 17
chr20_+_34742656	32.056	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr1_+_151254740	31.850	NM_020832	ZNF687	zinc finger protein 687
chr11_+_62475113	31.517	NM_012202	GNG3	guanine nucleotide binding protein (G protein), gamma 3
chr17_-_7197811	30.890		YBX2	Y box binding protein 2
chr10_+_124220990	30.604	NM_002775	HTRA1	HtrA serine peptidase 1
chr1_-_38512446	30.493	NM_002699	POU3F1	POU class 3 homeobox 1
chr10_-_118501981	29.955	NM_025015	HSPA12A	heat shock 70kDa protein 12A
chr12_+_79258794	29.748		SYT1	synaptotagmin I
chr16_+_67198637	29.525		HSF4	heat shock transcription factor 4
chr7_+_100136845	29.219		AGFG2	ArfGAP with FG repeats 2
chr6_+_99872769	29.090
chr11_-_125366048	29.055	NM_005103 NM_022549	FEZ1	fasciculation and elongation protein zeta 1 (zygin I)
chr3_-_9439122	28.825		LOC440944	uncharacterized LOC440944
chr1_-_182360400	28.534	NM_001033056	GLUL	glutamate-ammonia ligase
chr16_+_222845	27.945	NM_000517	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr11_+_117070039	27.767	NM_001001522 NM_003186	TAGLN	transgelin
chr7_-_75368216	26.844		HIP1	huntingtin interacting protein 1
chr4_-_176733413	26.613		GPM6A	glycoprotein M6A
chr8_-_82359620	26.507	NM_002677	PMP2	peripheral myelin protein 2
chr17_-_7197866	26.228	NM_015982	YBX2	Y box binding protein 2
chr1_-_46598250	26.185	NM_003629 NM_001114172	PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr2_-_74709965	25.825		CCDC142	coiled-coil domain containing 142
chr1_+_2005083	25.611	NM_001033581	PRKCZ	protein kinase C, zeta
chr14_-_103988829	25.520		CKB	creatine kinase, brain
chr1_+_171810611	25.303	NM_001136127 NM_015569	DNM3	dynamin 3
chr1_-_182360181	25.197		GLUL	glutamate-ammonia ligase
chr20_-_3154169	25.187		ProSAPiP1	ProSAPiP1 protein
chrX_-_70288155	25.014	NM_013346	SNX12	sorting nexin 12
chr6_-_46459710	24.937	NM_001251973	RCAN2	regulator of calcineurin 2
chr16_-_2264776	24.724	NM_001042371	PGP	phosphoglycolate phosphatase
chr19_+_35630391	24.689	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr16_-_31085503	24.454	NM_024706	ZNF668	zinc finger protein 668
chr4_-_57522469	24.040	NM_001145459 NM_139211	HOPX	HOP homeobox
chr11_+_61197574	24.008	NM_017841	SDHAF2	succinate dehydrogenase complex assembly factor 2
chr3_+_15469052	23.889	NM_033083	EAF1	ELL associated factor 1
chr6_-_111136616	23.882		CDK19	cyclin-dependent kinase 19
chrX_-_13835313	23.869	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr14_-_106610338	23.854		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr8_-_80679897	23.819	NM_001040708 NM_012258	HEY1	hairy/enhancer-of-split related with YRPW motif 1
chr11_+_124609841	23.576		NRGN	neurogranin (protein kinase C substrate, RC3)
chr8_-_24814028	23.540	NM_006158	NEFL	neurofilament, light polypeptide
chr13_+_58207858	23.535		PCDH17	protocadherin 17
chr7_+_142552547	23.335	NM_004445	EPHB6	EPH receptor B6
chr5_-_149535138	23.323		PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chrX_+_68048792	23.176	NM_004429	EFNB1	ephrin-B1
chr17_+_26699093	23.106		SARM1	sterile alpha and TIR motif containing 1
chr3_+_115342150	23.042	NM_001130064 NM_002045	GAP43	growth associated protein 43
chr16_-_3930713	22.744		CREBBP	CREB binding protein
chr1_-_203055088	22.591		MYOG	myogenin (myogenic factor 4)
chr14_-_23834417	22.537		EFS	embryonal Fyn-associated substrate
chr4_-_176733901	22.497		GPM6A	glycoprotein M6A
chr17_-_7197896	22.324		YBX2	Y box binding protein 2
chr8_-_27115897	22.273	NM_030795	STMN4	stathmin-like 4
chr3_+_50306305	22.165		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr5_-_42811959	22.077	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr3_+_238535	21.885		CHL1	cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr19_-_55866063	21.654	NM_144613	COX6B2	cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr15_-_83349134	21.545		AP3B2	adaptor-related protein complex 3, beta 2 subunit
chr16_-_49315682	21.544	NM_004352	CBLN1	cerebellin 1 precursor
chr12_+_79439432	21.257	NM_001135806	SYT1	synaptotagmin I
chr12_-_3982394	21.154	NM_020367	PARP11	poly (ADP-ribose) polymerase family, member 11
chr16_-_30934437	21.111		FBXL19-AS1	FBXL19 antisense RNA 1 (non-protein coding)
chr10_-_119301750	20.939		EMX2OS	EMX2 opposite strand/antisense RNA (non-protein coding)
chr17_-_74449272	20.936	NM_022066	UBE2O	ubiquitin-conjugating enzyme E2O
chr17_+_48172508	20.824	NM_001199900 NM_002611 NM_001199899	PDK2	pyruvate dehydrogenase kinase, isozyme 2
chr15_-_76030958	20.815		DNM1P35	DNM1 pseudogene 35
chr17_-_74449220	20.732		UBE2O	ubiquitin-conjugating enzyme E2O
chr17_+_17942584	20.595	NM_024052	C17orf39	chromosome 17 open reading frame 39
chrX_-_13835012	20.420		GPM6B	glycoprotein M6B
chr1_-_223537400	20.349	NM_001037175 NM_017982	SUSD4	sushi domain containing 4
chr1_+_22963097	20.337	NM_015991	C1QA	complement component 1, q subcomponent, A chain
chr15_-_65360297	20.223	NM_016563	RASL12	RAS-like, family 12
chr22_+_22735207	20.123		IGLJ3	immunoglobulin lambda joining 3
chr11_+_113930296	20.109		ZBTB16	zinc finger and BTB domain containing 16
chr5_+_31639424	20.062		PDZD2	PDZ domain containing 2
chr17_+_7554239	19.856	NM_001678	ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr6_+_7108864	19.694		RREB1	ras responsive element binding protein 1
chr11_-_66725790	19.564	NM_000920 NM_001040716	PC	pyruvate carboxylase
chr16_+_15528324	19.500	NM_033201	C16orf45	chromosome 16 open reading frame 45
chr7_+_65338161	19.467	NM_173517	VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr1_-_114354906	19.429	NM_018364	RSBN1	round spermatid basic protein 1
chr12_+_53817638	19.348	NM_001164690 NM_001164691 NM_020547	AMHR2	anti-Mullerian hormone receptor, type II
chr19_+_50270263	19.337		AP2A1	adaptor-related protein complex 2, alpha 1 subunit
chr19_-_58427934	19.333	NM_152475	ZNF417	zinc finger protein 417
chr11_+_113930430	19.253	NM_006006	ZBTB16	zinc finger and BTB domain containing 16
chr17_+_28256873	19.226	NM_001145053	EFCAB5	EF-hand calcium binding domain 5
chr19_+_42829760	19.163	NM_001410	MEGF8	multiple EGF-like-domains 8
chr5_+_140810326	19.085		PCDHGA12	protocadherin gamma subfamily A, 12
chr3_+_115342302	19.016		GAP43	growth associated protein 43
chr5_+_140810181	18.937		PCDHGA12	protocadherin gamma subfamily A, 12
chr2_-_172864747	18.908
chr17_-_1548992	18.844	NM_003693 NM_145350 NM_145352	SCARF1	scavenger receptor class F, member 1
chr20_-_3149070	18.771	NM_014731	ProSAPiP1	ProSAPiP1 protein
chrX_-_47479229	18.733	NM_006950 NM_133499	SYN1	synapsin I
chr17_-_17942326	18.568	NM_145691	ATPAF2	ATP synthase mitochondrial F1 complex assembly factor 2
chr5_-_142065991	18.482	NM_033136	FGF1	fibroblast growth factor 1 (acidic)
chr3_-_10749715	18.365		ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr9_+_35538628	18.260	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr3_-_13008959	18.227	NM_014869	IQSEC1	IQ motif and Sec7 domain 1
chr7_+_98246595	18.195	NM_002523	NPTX2	neuronal pentraxin II
chr7_+_100136784	18.180	NM_006076	AGFG2	ArfGAP with FG repeats 2
chr4_+_72102249	18.173		SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr11_-_133402227	18.131	NM_001012393	OPCML	opioid binding protein/cell adhesion molecule-like
chr9_-_139907614	18.128		ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr1_-_203055376	18.107	NM_002479	MYOG	myogenin (myogenic factor 4)
chr14_+_45431333	17.983	NM_015091	FAM179B	family with sequence similarity 179, member B
chr13_-_67804432	17.974	NM_020403 NM_203487	PCDH9	protocadherin 9
chr18_-_74729049	17.973	NM_001025081 NM_001025090 NM_001025092 NM_002385	MBP	myelin basic protein
chr6_+_31126114	17.921	NM_001077511 NM_007109	TCF19	transcription factor 19
chr16_-_70713927	17.911		MTSS1L	metastasis suppressor 1-like
chr17_+_29421956	17.835		NF1	neurofibromin 1
chr7_+_86273951	17.801		GRM3	glutamate receptor, metabotropic 3
chr2_+_24272627	17.775		FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr11_+_121461070	17.718		SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr12_+_122064448	17.693	NM_032790	ORAI1	ORAI calcium release-activated calcium modulator 1
chr5_+_149737296	17.570		TCOF1	Treacher Collins-Franceschetti syndrome 1
chr10_+_64133915	17.550	NM_014951 NM_199450 NM_199451	ZNF365	zinc finger protein 365
chr22_-_19512859	17.541	NM_001130861 NM_003277	CLDN5	claudin 5
chr2_+_220042986	17.427		FAM134A	family with sequence similarity 134, member A
chr7_-_143059696	17.421	NM_001031690	FAM131B	family with sequence similarity 131, member B
chr3_+_23987514	17.377	NM_001145425	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr15_-_90347173	17.370		ANPEP	alanyl (membrane) aminopeptidase
chr17_-_78450247	17.362	NM_002522	NPTX1	neuronal pentraxin I
chr5_-_149792370	17.355	NM_001025158 NM_001025159 NM_004355	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr19_-_47164289	17.304	NM_145056	DACT3	dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr7_-_31380507	17.277	NM_022728	NEUROD6	neurogenic differentiation 6
chr10_+_75532252	17.243		FUT11	fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
chr16_-_31084822	17.240	NM_001172668	ZNF668	zinc finger protein 668
chr15_+_64443909	17.177	NM_024798	SNX22	sorting nexin 22
chr18_-_74728963	17.127		MBP	myelin basic protein
chr5_-_95297424	17.104		ELL2	elongation factor, RNA polymerase II, 2
chr3_-_169899372	17.099		PHC3	polyhomeotic homolog 3 (Drosophila)
chr19_+_50380681	17.034	NM_001168222 NM_024682	TBC1D17	TBC1 domain family, member 17
chr11_-_132812870	16.985	NM_002545	OPCML	opioid binding protein/cell adhesion molecule-like
chr8_+_141521365	16.962	NM_017444	CHRAC1	chromatin accessibility complex 1
chr4_+_166299942	16.871	NM_001873	CPE	carboxypeptidase E
chr3_+_50306578	16.704		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr16_+_28834407	16.691	NM_007245 NM_145714 NM_148414 NM_148415 NM_148416	ATXN2L	ataxin 2-like
chr11_-_62476976	16.689		BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr6_+_36238236	16.569	NM_001145717	PNPLA1	patatin-like phospholipase domain containing 1
chr6_+_31554475	16.548	NM_205837	LST1	leukocyte specific transcript 1
chr14_-_23834841	16.519	NM_005864 NM_032459	EFS	embryonal Fyn-associated substrate
chr8_+_22462532	16.492	NM_021174	KIAA1967	KIAA1967
chr19_+_50353942	16.479		PTOV1	prostate tumor overexpressed 1
chr10_+_75545363	16.459	NM_001242487 NM_001242488 NM_015037	KIAA0913	KIAA0913
chr15_+_84116172	16.381		SH3GL3	SH3-domain GRB2-like 3
chr2_+_24272583	16.355	NM_004116 NM_054033	FKBP1B	FK506 binding protein 1B, 12.6 kDa
chrX_-_107979606	16.344	NM_003604	IRS4	insulin receptor substrate 4
chr16_+_28834565	16.304		ATXN2L	ataxin 2-like
chr6_-_166796363	16.272		BRP44L	brain protein 44-like
chr19_+_45409003	16.266	NM_000041	APOE	apolipoprotein E
chr9_-_96717544	16.261	NM_021570	BARX1	BARX homeobox 1
chr8_-_132052834	16.238	NM_001115	ADCY8	adenylate cyclase 8 (brain)
chr2_-_220173693	16.203	NM_001199764	PTPRN	protein tyrosine phosphatase, receptor type, N
chr2_-_224467049	16.160		SCG2	secretogranin II
chr2_-_73520448	16.122	NM_001965	EGR4	early growth response 4
chr9_-_91793375	16.116		SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr2_+_128643535	16.114
chr15_-_75165595	16.089	NM_005697	SCAMP2	secretory carrier membrane protein 2
chr14_-_51562421	16.065	NM_015163 NM_052978	TRIM9	tripartite motif containing 9
chr3_-_15468981	16.061	NM_152396	METTL6	methyltransferase like 6
chr2_-_73053030	16.046	NM_015189	EXOC6B	exocyst complex component 6B
chr2_-_175712276	16.043	NM_001206602	CHN1	chimerin (chimaerin) 1
chr16_+_28834360	16.040		ATXN2L	ataxin 2-like
chr8_+_1952875	15.948		KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr17_+_7554711	15.861		ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr5_-_149792276	15.849		CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_+_19837599	15.789	NM_001546	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr6_-_31763415	15.780		VARS	valyl-tRNA synthetase

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.38	1.24e-31	GO:0023052	signaling
1.22	5.89e-31	GO:0065007	biological regulation
1.13	3.02e-27	GO:0009987	cellular process
1.38	5.55e-27	GO:0007275	multicellular organismal development
1.42	1.12e-26	GO:0048731	system development
1.21	1.77e-26	GO:0050789	regulation of biological process
1.35	6.15e-26	GO:0032502	developmental process
1.27	1.72e-25	GO:0032501	multicellular organismal process
1.22	1.90e-25	GO:0050794	regulation of cellular process
1.38	9.42e-25	GO:0048856	anatomical structure development
1.34	3.61e-21	GO:0007165	signal transduction
1.55	1.54e-20	GO:0007399	nervous system development
1.75	2.51e-18	GO:0007267	cell-cell signaling
1.63	1.05e-17	GO:0007154	cell communication
1.42	4.46e-15	GO:0007166	cell surface receptor linked signaling pathway
1.25	2.14e-14	GO:0051716	cellular response to stimulus
1.37	6.72e-14	GO:0048869	cellular developmental process
1.45	6.85e-14	GO:0009653	anatomical structure morphogenesis
1.37	2.51e-13	GO:0030154	cell differentiation
1.81	3.64e-13	GO:0019226	transmission of nerve impulse
1.81	3.64e-13	GO:0035637	multicellular organismal signaling
1.48	4.73e-13	GO:0051239	regulation of multicellular organismal process
1.38	9.41e-13	GO:0048513	organ development
1.35	1.41e-12	GO:0065008	regulation of biological quality
1.57	1.81e-12	GO:0022008	neurogenesis
1.30	3.65e-12	GO:0048518	positive regulation of biological process
1.64	1.38e-11	GO:0030182	neuron differentiation
1.56	2.89e-11	GO:0040011	locomotion
1.35	1.38e-10	GO:0048583	regulation of response to stimulus
1.54	1.40e-10	GO:0048699	generation of neurons
1.16	3.17e-10	GO:0050896	response to stimulus
1.72	3.28e-10	GO:0048858	cell projection morphogenesis
1.77	3.62e-10	GO:0007268	synaptic transmission
1.37	4.09e-10	GO:0023051	regulation of signaling
1.70	7.26e-10	GO:0006935	chemotaxis
1.70	7.26e-10	GO:0042330	taxis
1.70	7.71e-10	GO:0032990	cell part morphogenesis
1.77	8.72e-10	GO:0007409	axonogenesis
1.65	1.68e-09	GO:0048666	neuron development
1.74	1.78e-09	GO:0048812	neuron projection morphogenesis
1.75	1.85e-09	GO:0048667	cell morphogenesis involved in neuron differentiation
1.59	3.30e-09	GO:0010628	positive regulation of gene expression
1.69	3.76e-09	GO:0000904	cell morphogenesis involved in differentiation
1.60	3.98e-09	GO:0030030	cell projection organization
1.62	4.43e-09	GO:0000902	cell morphogenesis
1.47	5.33e-09	GO:0009605	response to external stimulus
1.68	6.06e-09	GO:0031175	neuron projection development
1.60	7.21e-09	GO:0032989	cellular component morphogenesis
1.83	9.77e-09	GO:0007411	axon guidance
1.50	1.03e-08	GO:0006351	transcription, DNA-dependent
1.29	1.17e-08	GO:0042221	response to chemical stimulus
1.28	1.22e-08	GO:0048522	positive regulation of cellular process
1.48	1.49e-08	GO:0048468	cell development
1.47	2.98e-08	GO:0050793	regulation of developmental process
1.67	3.53e-08	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.59	5.82e-08	GO:0009887	organ morphogenesis
1.27	6.14e-08	GO:0048519	negative regulation of biological process
1.43	6.80e-08	GO:0010646	regulation of cell communication
1.44	1.56e-07	GO:0032879	regulation of localization
1.50	1.84e-07	GO:0007155	cell adhesion
1.50	1.84e-07	GO:0022610	biological adhesion
1.25	2.11e-07	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50	2.41e-07	GO:2000026	regulation of multicellular organismal development
1.61	3.17e-07	GO:0007417	central nervous system development
1.28	3.72e-07	GO:0048523	negative regulation of cellular process
1.43	3.88e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.21	4.03e-07	GO:0051179	localization
1.52	5.28e-07	GO:0045595	regulation of cell differentiation
1.35	6.49e-07	GO:0009966	regulation of signal transduction
1.48	7.04e-07	GO:0051173	positive regulation of nitrogen compound metabolic process
1.43	8.48e-07	GO:0042127	regulation of cell proliferation
1.54	8.69e-07	GO:0045893	positive regulation of transcription, DNA-dependent
1.48	1.03e-06	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20	2.31e-06	GO:0080090	regulation of primary metabolic process
1.23	2.69e-06	GO:0051171	regulation of nitrogen compound metabolic process
1.44	3.27e-06	GO:0031328	positive regulation of cellular biosynthetic process
1.44	3.72e-06	GO:0009891	positive regulation of biosynthetic process
1.50	3.98e-06	GO:0051254	positive regulation of RNA metabolic process
1.71	5.04e-06	GO:0044057	regulation of system process
1.47	5.32e-06	GO:0010557	positive regulation of macromolecule biosynthetic process
1.23	5.84e-06	GO:0031326	regulation of cellular biosynthetic process
1.22	6.09e-06	GO:0009889	regulation of biosynthetic process
1.18	6.62e-06	GO:0019222	regulation of metabolic process
1.19	9.25e-06	GO:0031323	regulation of cellular metabolic process
1.44	1.06e-05	GO:0048584	positive regulation of response to stimulus
1.83	1.10e-05	GO:0030168	platelet activation
1.53	1.52e-05	GO:0007186	G-protein coupled receptor protein signaling pathway
2.11	1.97e-05	GO:0048705	skeletal system morphogenesis
1.65	1.98e-05	GO:0007420	brain development
1.55	2.15e-05	GO:0001775	cell activation
1.32	2.40e-05	GO:0035556	intracellular signal transduction
1.45	2.63e-05	GO:0051049	regulation of transport
1.58	4.20e-05	GO:0032583	regulation of gene-specific transcription
1.33	4.92e-05	GO:0009893	positive regulation of metabolic process
1.38	5.10e-05	GO:0032774	RNA biosynthetic process
1.20	8.13e-05	GO:0006810	transport
1.47	1.05e-04	GO:0048878	chemical homeostasis
1.46	1.09e-04	GO:0007167	enzyme linked receptor protein signaling pathway
1.23	1.20e-04	GO:0006355	regulation of transcription, DNA-dependent
1.21	1.23e-04	GO:0010468	regulation of gene expression
1.33	1.55e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.68	1.83e-04	GO:0001944	vasculature development
1.19	1.87e-04	GO:0051234	establishment of localization
1.53	2.18e-04	GO:0072358	cardiovascular system development
1.53	2.18e-04	GO:0072359	circulatory system development
1.22	2.49e-04	GO:0051252	regulation of RNA metabolic process
1.18	2.59e-04	GO:0060255	regulation of macromolecule metabolic process
1.63	3.01e-04	GO:0051093	negative regulation of developmental process
1.37	3.02e-04	GO:0009611	response to wounding
1.45	3.52e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.53	4.79e-04	GO:0051094	positive regulation of developmental process
1.47	4.85e-04	GO:0051253	negative regulation of RNA metabolic process
1.42	5.15e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.41	5.76e-04	GO:0009890	negative regulation of biosynthetic process
1.54	6.39e-04	GO:0016477	cell migration
2.11	6.73e-04	GO:0051924	regulation of calcium ion transport
1.68	7.04e-04	GO:0001568	blood vessel development
1.81	1.06e-03	GO:0003012	muscle system process
1.47	1.09e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.43	1.13e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20	1.21e-03	GO:0010556	regulation of macromolecule biosynthetic process
1.64	1.26e-03	GO:0007423	sensory organ development
1.48	1.35e-03	GO:0048585	negative regulation of response to stimulus
1.58	1.39e-03	GO:0007389	pattern specification process
1.98	1.64e-03	GO:0010959	regulation of metal ion transport
1.60	1.86e-03	GO:0001501	skeletal system development
1.51	2.22e-03	GO:0008285	negative regulation of cell proliferation
1.40	2.26e-03	GO:0009719	response to endogenous stimulus
1.60	2.34e-03	GO:0022603	regulation of anatomical structure morphogenesis
1.57	2.48e-03	GO:0045597	positive regulation of cell differentiation
1.29	2.53e-03	GO:0031325	positive regulation of cellular metabolic process
1.87	2.69e-03	GO:0034330	cell junction organization
1.87	2.69e-03	GO:0043269	regulation of ion transport
1.35	2.75e-03	GO:0009888	tissue development
1.49	2.77e-03	GO:0055082	cellular chemical homeostasis
1.54	3.07e-03	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.48	3.27e-03	GO:0048870	cell motility
1.48	3.27e-03	GO:0051674	localization of cell
1.50	3.52e-03	GO:0006873	cellular ion homeostasis
1.44	3.61e-03	GO:0006928	cellular component movement
3.43	3.99e-03	GO:0071396	cellular response to lipid
1.47	4.41e-03	GO:0050801	ion homeostasis
1.19	4.72e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.69	5.22e-03	GO:0048514	blood vessel morphogenesis
1.39	5.36e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.63	5.75e-03	GO:0045596	negative regulation of cell differentiation
1.28	5.90e-03	GO:0002376	immune system process
1.89	6.24e-03	GO:0034329	cell junction assembly
1.59	6.32e-03	GO:0040012	regulation of locomotion
1.57	6.42e-03	GO:0006140	regulation of nucleotide metabolic process
1.44	6.85e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.47	7.28e-03	GO:0010648	negative regulation of cell communication
1.82	7.59e-03	GO:0019935	cyclic-nucleotide-mediated signaling
2.50	7.61e-03	GO:0033993	response to lipid
2.45	8.05e-03	GO:0060348	bone development
1.40	8.19e-03	GO:0009725	response to hormone stimulus
2.36	8.51e-03	GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.86	9.50e-03	GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger
1.64	1.01e-02	GO:0003002	regionalization
1.40	1.07e-02	GO:0042060	wound healing
1.55	1.09e-02	GO:0060284	regulation of cell development
1.47	1.10e-02	GO:0023057	negative regulation of signaling
1.39	1.14e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.26	1.21e-02	GO:0010033	response to organic substance
1.22	1.22e-02	GO:0003008	system process
2.74	1.26e-02	GO:0003014	renal system process
1.55	1.29e-02	GO:0051046	regulation of secretion
1.76	1.36e-02	GO:0006936	muscle contraction
1.47	1.41e-02	GO:0060341	regulation of cellular localization
1.57	1.45e-02	GO:0051270	regulation of cellular component movement
2.65	1.48e-02	GO:0060349	bone morphogenesis
2.16	1.73e-02	GO:0010721	negative regulation of cell development
1.40	2.01e-02	GO:0050878	regulation of body fluid levels
1.79	2.03e-02	GO:0032844	regulation of homeostatic process
1.38	2.13e-02	GO:0010629	negative regulation of gene expression
1.31	2.40e-02	GO:0042592	homeostatic process
1.44	2.47e-02	GO:0048646	anatomical structure formation involved in morphogenesis
1.46	2.70e-02	GO:0009968	negative regulation of signal transduction
1.93	2.94e-02	GO:0001822	kidney development
1.83	2.95e-02	GO:0030111	regulation of Wnt receptor signaling pathway
1.44	3.18e-02	GO:0046903	secretion
1.55	3.23e-02	GO:0030029	actin filament-based process
1.56	3.49e-02	GO:0035295	tube development
1.95	3.63e-02	GO:0045761	regulation of adenylate cyclase activity
1.53	3.98e-02	GO:0016337	cell-cell adhesion
1.57	4.29e-02	GO:2000145	regulation of cell motility
1.23	4.35e-02	GO:0065009	regulation of molecular function
1.52	4.86e-02	GO:0007610	behavior
1.39	4.91e-02	GO:0010647	positive regulation of cell communication
1.57	4.92e-02	GO:0030334	regulation of cell migration
1.30	4.94e-02	GO:0006811	ion transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.44	3.14e-23	GO:0044459	plasma membrane part
1.53	6.44e-17	GO:0005887	integral to plasma membrane
1.52	9.49e-17	GO:0031226	intrinsic to plasma membrane
1.21	8.18e-12	GO:0071944	cell periphery
1.21	2.65e-11	GO:0005886	plasma membrane
1.47	1.35e-08	GO:0005626	insoluble fraction
1.68	4.17e-08	GO:0043005	neuron projection
1.66	1.13e-07	GO:0045202	synapse
1.38	1.18e-07	GO:0000267	cell fraction
1.44	2.98e-07	GO:0005624	membrane fraction
1.91	4.40e-06	GO:0030424	axon
1.65	3.44e-05	GO:0044456	synapse part
2.27	1.30e-04	GO:0033267	axon part
1.35	1.51e-04	GO:0042995	cell projection
1.76	2.25e-04	GO:0030425	dendrite
1.40	8.52e-04	GO:0030054	cell junction
2.11	1.28e-03	GO:0030139	endocytic vesicle
2.64	1.30e-03	GO:0043679	axon terminus
1.70	3.29e-03	GO:0044297	cell body
2.52	3.81e-03	GO:0044306	neuron projection terminus
1.44	6.31e-03	GO:0044463	cell projection part
1.48	1.10e-02	GO:0044433	cytoplasmic vesicle part
1.67	1.12e-02	GO:0043025	neuronal cell body
1.59	1.30e-02	GO:0034702	ion channel complex
1.51	1.68e-02	GO:0012506	vesicle membrane
1.29	1.83e-02	GO:0031982	vesicle
1.29	2.98e-02	GO:0031410	cytoplasmic vesicle
2.65	3.08e-02	GO:0034704	calcium channel complex
1.71	3.25e-02	GO:0034703	cation channel complex
1.49	4.47e-02	GO:0030659	cytoplasmic vesicle membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.09	1.77e-16	GO:0005488	binding
1.56	1.96e-14	GO:0001071	nucleic acid binding transcription factor activity
1.56	1.96e-14	GO:0003700	sequence-specific DNA binding transcription factor activity
1.15	5.92e-14	GO:0005515	protein binding
1.62	7.31e-12	GO:0043565	sequence-specific DNA binding
1.34	8.96e-05	GO:0030528	transcription regulator activity
1.41	2.18e-04	GO:0046983	protein dimerization activity
1.52	2.89e-04	GO:0015267	channel activity
1.51	3.36e-04	GO:0022803	passive transmembrane transporter activity
2.25	3.75e-04	GO:0005262	calcium channel activity
1.64	3.96e-04	GO:0005261	cation channel activity
2.54	4.95e-04	GO:0003707	steroid hormone receptor activity
2.49	5.34e-04	GO:0004879	ligand-dependent nuclear receptor activity
1.58	7.11e-04	GO:0022836	gated channel activity
1.87	1.02e-03	GO:0005516	calmodulin binding
1.30	1.20e-03	GO:0005102	receptor binding
1.49	2.05e-03	GO:0005216	ion channel activity
1.48	2.75e-03	GO:0022838	substrate-specific channel activity
1.45	4.31e-03	GO:0042803	protein homodimerization activity
1.79	5.26e-03	GO:0022843	voltage-gated cation channel activity
1.33	7.36e-03	GO:0042802	identical protein binding
1.31	2.23e-02	GO:0019899	enzyme binding
1.39	2.39e-02	GO:0060589	nucleoside-triphosphatase regulator activity
1.40	2.44e-02	GO:0030695	GTPase regulator activity
1.18	2.49e-02	GO:0004871	signal transducer activity
1.18	2.49e-02	GO:0060089	molecular transducer activity
1.62	3.27e-02	GO:0005244	voltage-gated ion channel activity
1.62	3.27e-02	GO:0022832	voltage-gated channel activity
2.03	4.17e-02	GO:0005200	structural constituent of cytoskeleton
1.96	4.25e-02	GO:0019199	transmembrane receptor protein kinase activity