Motif ID: MAZ.p2

Z-value: 2.376


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_29817810-0.491.7e-14Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_113930296 38.010 ZBTB16
zinc finger and BTB domain containing 16
chr11_+_113930430 35.012 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr21_-_45759077 32.978 C21orf2
chromosome 21 open reading frame 2
chr6_-_29600859 31.482 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_-_29600959 30.179 NM_001470
NM_021904
GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr16_+_2587989 29.817 PDPK1
3-phosphoinositide dependent protein kinase-1
chr1_+_6845381 28.987 NM_001195563
NM_001242701
NM_015215
CAMTA1


calmodulin binding transcription activator 1


chr6_-_29595746 28.414 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr16_+_2588000 27.856 PDPK1
3-phosphoinositide dependent protein kinase-1
chr12_-_6798419 27.339 ZNF384
zinc finger protein 384
chr1_-_15850776 25.605 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr3_-_13008959 24.352 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr7_+_64498643 24.159 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr7_-_158380360 23.427 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr6_-_29600668 22.876 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_-_29595934 22.780 NM_021903
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr3_-_132441216 21.890 NPHP3
nephronophthisis 3 (adolescent)
chr4_-_5894695 21.644 NM_001014809
CRMP1
collapsin response mediator protein 1
chr2_+_10183630 21.362 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr12_-_6798528 21.357 NM_133476
ZNF384
zinc finger protein 384
chr11_-_64512265 20.657 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_+_2588051 20.650 PDPK1
3-phosphoinositide dependent protein kinase-1
chr7_-_105029251 20.585


chr16_-_402617 20.368 NM_003502
NM_181050
AXIN1

axin 1

chrY_-_1281526 20.168 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr7_+_44143945 20.120 NM_001129
AEBP1
AE binding protein 1
chr7_-_102257199 20.106 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr3_+_52444514 20.049 NM_016483
NM_173341
PHF7

PHD finger protein 7

chr19_-_4457789 19.790 NM_025241
UBXN6
UBX domain protein 6
chr10_+_76586299 19.769 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr8_+_28748030 19.130 NM_024567
HMBOX1
homeobox containing 1
chr7_-_102257135 18.971 RASA4
RAS p21 protein activator 4
chr6_+_37137882 18.970 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr4_-_5890142 18.945 CRMP1
collapsin response mediator protein 1
chr20_+_44650260 18.767 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr19_+_56652689 18.681 ZNF444
zinc finger protein 444
chr7_+_44144002 18.449 AEBP1
AE binding protein 1
chr9_-_132805256 18.344 FNBP1
formin binding protein 1
chr16_+_2588021 18.285 PDPK1
3-phosphoinositide dependent protein kinase-1
chr17_+_29421956 18.189 NF1
neurofibromin 1
chr12_-_6798619 18.107 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr4_-_1166364 18.039 SPON2
spondin 2, extracellular matrix protein
chr3_+_52444673 17.953 PHF7
PHD finger protein 7
chr4_-_1166458 17.927 SPON2
spondin 2, extracellular matrix protein
chr2_-_16847070 17.840 NM_030797
FAM49A
family with sequence similarity 49, member A
chr3_-_47620186 17.507 NM_001206943
NM_001206944
NM_006574
CSPG5


chondroitin sulfate proteoglycan 5 (neuroglycan C)


chr8_+_28747885 17.394 NM_001135726
HMBOX1
homeobox containing 1
chr16_+_2587951 17.381 NM_002613
NM_031268
PDPK1

3-phosphoinositide dependent protein kinase-1

chr17_+_47653474 17.379 NXPH3
neurexophilin 3
chr16_-_88923233 17.314 GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr9_-_132805456 16.953 NM_015033
FNBP1
formin binding protein 1
chr1_-_11714738 16.923 NM_012168
FBXO2
F-box protein 2
chr4_-_1166547 16.755 NM_012445
SPON2
spondin 2, extracellular matrix protein
chrX_-_17879355 16.746 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr10_+_135192694 16.731 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr19_+_36266366 16.713 NM_001172630
NM_052948
ARHGAP33

Rho GTPase activating protein 33

chr2_-_109150596 16.622 FLJ38668
uncharacterized LOC644903
chr19_+_708766 16.430 NM_001040134
NM_002579
PALM

paralemmin

chr12_-_54982271 16.386 NM_006741
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr2_+_30369868 16.210 YPEL5
yippee-like 5 (Drosophila)
chr19_+_41284161 16.209 RAB4B-EGLN2
RAB4B
RAB4B-EGLN2 readthrough
RAB4B, member RAS oncogene family
chr19_+_3359138 16.207 NM_001245005
NM_205843
NFIC

nuclear factor I/C (CCAAT-binding transcription factor)

chr15_+_65134081 15.988 NM_001195059
NM_025201
PLEKHO2

pleckstrin homology domain containing, family O member 2

chr11_-_68518910 15.887 MTL5
metallothionein-like 5, testis-specific (tesmin)
chr10_+_111767877 15.806 ADD3
adducin 3 (gamma)
chr19_+_56652529 15.564 NM_001253792
NM_018337
ZNF444

zinc finger protein 444

chr4_-_1166378 15.535 SPON2
spondin 2, extracellular matrix protein
chr15_-_23086290 15.392 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr4_+_3294711 15.281 RGS12
regulator of G-protein signaling 12
chr1_-_1051458 15.265 C1orf159
chromosome 1 open reading frame 159
chr2_+_230787195 15.222 NM_174899
FBXO36
F-box protein 36
chr4_-_1166959 15.195 NM_001128325
SPON2
spondin 2, extracellular matrix protein
chr19_+_47759802 15.004 CCDC9
coiled-coil domain containing 9
chr2_+_30369749 14.971 NM_001127399
NM_001127400
NM_001127401
NM_016061
YPEL5



yippee-like 5 (Drosophila)



chr1_+_211432855 14.961 RCOR3
REST corepressor 3
chr18_+_77155966 14.900 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr7_+_65338161 14.809 NM_173517
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr16_+_56225301 14.742 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr12_+_57522247 14.730 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr15_+_74833517 14.666 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr7_+_97910978 14.663 NM_001159491
NM_015379
BRI3

brain protein I3

chr6_-_109804432 14.529 NM_001164313
NM_014797
ZBTB24

zinc finger and BTB domain containing 24

chr21_-_47648685 14.457 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr19_+_18208596 14.422 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr19_+_47759730 14.398 NM_015603
CCDC9
coiled-coil domain containing 9
chr9_-_36401149 14.387 NM_194330
RNF38
ring finger protein 38
chr8_-_144241678 14.359 LY6H
lymphocyte antigen 6 complex, locus H
chr6_-_34664517 14.305 C6orf106
chromosome 6 open reading frame 106
chr20_-_23618382 14.302 NM_000099
CST3
cystatin C
chr12_+_4382882 14.283 NM_001759
CCND2
cyclin D2
chr19_+_35634153 14.276 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chr4_+_154387450 14.259 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr21_+_44394691 14.242 PKNOX1
PBX/knotted 1 homeobox 1
chr16_+_8768403 14.230 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr12_+_132379262 14.197 NM_003565
ULK1
unc-51-like kinase 1 (C. elegans)
chr1_+_184356227 14.139 C1orf21
chromosome 1 open reading frame 21
chr11_-_64512925 13.918 NM_153819
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr10_-_21462987 13.781 NEBL
nebulette
chr18_+_77155943 13.660 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr13_+_31191829 13.589 NM_005800
USPL1
ubiquitin specific peptidase like 1
chr6_+_37787592 13.555 ZFAND3
zinc finger, AN1-type domain 3
chr18_+_77155927 13.550 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr19_+_41284068 13.518 NM_016154
RAB4B
RAB4B, member RAS oncogene family
chr3_-_132441302 13.429 NM_153240
NPHP3-ACAD11
NPHP3
NPHP3-ACAD11 readthrough
nephronophthisis 3 (adolescent)
chr1_-_11714396 13.427 FBXO2
F-box protein 2
chrX_-_1331526 13.391 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr1_-_154193044 13.345 C1orf43
chromosome 1 open reading frame 43
chr2_-_43453146 13.288 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr1_-_182360400 13.274 NM_001033056
GLUL
glutamate-ammonia ligase
chr10_-_99790584 13.245 NM_001206528
NM_018058
CRTAC1

cartilage acidic protein 1

chr11_-_134281725 13.209 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr1_-_11714471 13.167 FBXO2
F-box protein 2
chr1_+_44584521 13.165 NM_173484
KLF17
Kruppel-like factor 17
chr4_-_5890266 13.046 NM_001313
CRMP1
collapsin response mediator protein 1
chr17_+_42385780 13.040 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr11_-_130184314 13.030 ZBTB44
zinc finger and BTB domain containing 44
chr11_+_57365577 12.920 NM_001032295
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr14_-_21493122 12.883 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr14_+_21538339 12.787 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr16_+_226678 12.670 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr14_-_81687265 12.599 NM_015859
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr1_-_23810627 12.595 ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr2_-_60780767 12.588 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr16_-_88923348 12.581 NM_000512
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr15_-_75743776 12.533 NM_015477
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr6_-_33285493 12.522 NM_005453
ZBTB22
zinc finger and BTB domain containing 22
chr19_+_7968762 12.461 MAP2K7
mitogen-activated protein kinase kinase 7
chr19_+_48972574 12.457 CYTH2
cytohesin 2
chr16_-_402398 12.424 AXIN1
axin 1
chr6_-_112194430 12.396 FYN
FYN oncogene related to SRC, FGR, YES
chr10_+_111985628 12.396 NM_005962
MXI1
MAX interactor 1
chr18_-_29522988 12.387 TRAPPC8
trafficking protein particle complex 8
chr21_+_47649066 12.366 MCM3AP-AS1
MCM3AP antisense RNA 1 (non-protein coding)
chr1_+_211432693 12.353 NM_001136223
NM_001136224
NM_001136225
RCOR3


REST corepressor 3


chr16_+_222845 12.268 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr8_-_144241725 12.196 NM_001135655
LY6H
lymphocyte antigen 6 complex, locus H
chr11_-_64410785 12.155 NM_138734
NRXN2
neurexin 2
chr1_+_104068312 12.126 RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr20_-_48099178 12.116 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr9_-_92112887 12.101 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr16_+_2802605 12.086 SRRM2
serine/arginine repetitive matrix 2
chr10_+_104503724 12.079 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr15_+_69222838 12.060 NM_145658
NM_001184780
SPESP1
NOX5
sperm equatorial segment protein 1
NADPH oxidase, EF-hand calcium binding domain 5
chr19_-_36246411 12.044 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr12_+_54332575 11.998 NM_017410
HOXC13
homeobox C13
chr18_-_65183922 11.995 NM_032160
DSEL
dermatan sulfate epimerase-like
chr17_-_63052744 11.995 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr15_+_74422742 11.990 NM_020851
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr22_-_19279183 11.961 NM_001835
NM_007098
CLTCL1

clathrin, heavy chain-like 1

chr16_+_89894853 11.960 NM_032451
SPIRE2
spire homolog 2 (Drosophila)
chr19_+_7968820 11.905 MAP2K7
mitogen-activated protein kinase kinase 7
chr19_+_7968701 11.890 MAP2K7
mitogen-activated protein kinase kinase 7
chr6_-_46459010 11.871 NM_001251974
RCAN2
regulator of calcineurin 2
chr14_-_81687574 11.864 NM_201595
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr19_+_7968765 11.860 MAP2K7
mitogen-activated protein kinase kinase 7
chr11_-_64490654 11.857 NM_015080
NM_138732
NRXN2

neurexin 2

chr3_-_9439122 11.847 LOC440944
uncharacterized LOC440944
chr3_+_52489617 11.814 NISCH
nischarin
chr16_+_1203240 11.800 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr20_+_1206763 11.786 NM_001136566
RAD21L1
RAD21-like 1 (S. pombe)
chr17_-_63052707 11.699 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr19_+_42788605 11.662 NM_015125
CIC
capicua homolog (Drosophila)
chr12_-_49392909 11.644 NM_015086
DDN
dendrin
chr11_+_117049838 11.620 NM_001040455
SIDT2
SID1 transmembrane family, member 2
chr1_+_1981902 11.616 NM_002744
PRKCZ
protein kinase C, zeta
chrX_+_43514157 11.615 MAOA
monoamine oxidase A
chr19_-_4065467 11.541 ZBTB7A
zinc finger and BTB domain containing 7A
chr3_+_20081853 11.539 KAT2B
K(lysine) acetyltransferase 2B
chr19_+_7968774 11.533 MAP2K7
mitogen-activated protein kinase kinase 7
chr14_+_96505566 11.521 NM_001252507
C14orf132
chromosome 14 open reading frame 132
chr19_-_36523540 11.479 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chrX_+_11776708 11.470 NM_001193270
MSL3
male-specific lethal 3 homolog (Drosophila)
chr2_+_79740059 11.457 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr16_+_2802708 11.414 SRRM2
serine/arginine repetitive matrix 2
chr4_+_57774365 11.405 REST
RE1-silencing transcription factor
chr3_+_58223228 11.329 NM_020676
ABHD6
abhydrolase domain containing 6
chr16_-_30134582 11.320 NM_001040056
NM_001109891
NM_002746
MAPK3


mitogen-activated protein kinase 3


chr3_+_52489646 11.303 NISCH
nischarin
chrX_-_70288155 11.275 NM_013346
SNX12
sorting nexin 12
chr1_-_15850718 11.274 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr1_+_184356128 11.256 NM_030806
C1orf21
chromosome 1 open reading frame 21
chr6_-_32095993 11.254 NM_001136153
NM_004381
ATF6B

activating transcription factor 6 beta

chr16_-_325867 11.248 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr2_+_30369800 11.235 YPEL5
yippee-like 5 (Drosophila)
chr16_+_11762235 11.222 NM_003498
SNN
stannin
chr11_-_2906960 11.222 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr7_-_105029321 11.164 NM_182692
SRPK2
SRSF protein kinase 2
chr19_-_6279927 11.153 NM_005934
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr22_+_50946654 11.062 NCAPH2
non-SMC condensin II complex, subunit H2
chr19_+_41305333 11.035 NM_053046
EGLN2
egl nine homolog 2 (C. elegans)
chr19_+_4639526 11.035 NM_152362
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr6_-_70506524 11.030 LMBRD1
LMBR1 domain containing 1
chr9_-_113800980 11.003 LPAR1
lysophosphatidic acid receptor 1
chr19_-_6279797 10.999


chr15_+_90931509 10.989 IQGAP1
IQ motif containing GTPase activating protein 1
chr21_-_45759268 10.963 NM_004928
C21orf2
chromosome 21 open reading frame 2
chr6_-_112194648 10.950 NM_002037
FYN
FYN oncogene related to SRC, FGR, YES
chr17_+_64960754 10.920 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr12_+_112204690 10.869 NM_000690
NM_001204889
ALDH2

aldehyde dehydrogenase 2 family (mitochondrial)

chr2_+_242641310 10.867 NM_032329
ING5
inhibitor of growth family, member 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.18 1.77e-95 GO:0009987 cellular process
1.25 9.18e-56 GO:0044237 cellular metabolic process
1.23 1.06e-45 GO:0044238 primary metabolic process
1.21 4.66e-45 GO:0008152 metabolic process
1.18 7.14e-42 GO:0065007 biological regulation
1.19 5.41e-40 GO:0050789 regulation of biological process
1.28 5.54e-40 GO:0044260 cellular macromolecule metabolic process
1.20 8.73e-39 GO:0050794 regulation of cellular process
1.24 4.41e-36 GO:0043170 macromolecule metabolic process
1.27 1.66e-31 GO:0032502 developmental process
1.29 1.18e-29 GO:0016043 cellular component organization
1.28 4.36e-29 GO:0071840 cellular component organization or biogenesis
1.29 3.24e-27 GO:0048856 anatomical structure development
1.27 6.11e-27 GO:0007275 multicellular organismal development
1.26 1.19e-26 GO:0023052 signaling
1.30 1.41e-25 GO:0048731 system development
1.33 3.58e-25 GO:0044249 cellular biosynthetic process
1.26 6.13e-25 GO:0080090 regulation of primary metabolic process
1.26 6.47e-25 GO:0031323 regulation of cellular metabolic process
1.30 1.28e-24 GO:0048518 positive regulation of biological process
1.31 2.03e-24 GO:0009058 biosynthetic process
1.31 1.28e-23 GO:0044267 cellular protein metabolic process
1.23 3.91e-23 GO:0019222 regulation of metabolic process
1.31 6.79e-23 GO:0048519 negative regulation of biological process
1.25 2.71e-22 GO:0060255 regulation of macromolecule metabolic process
1.36 3.71e-22 GO:0006464 protein modification process
1.33 3.97e-22 GO:0048523 negative regulation of cellular process
1.30 9.07e-22 GO:0048522 positive regulation of cellular process
1.28 1.14e-21 GO:0071841 cellular component organization or biogenesis at cellular level
1.50 1.52e-21 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.29 2.83e-21 GO:0071842 cellular component organization at cellular level
1.26 3.48e-21 GO:0034641 cellular nitrogen compound metabolic process
1.25 1.07e-20 GO:0006807 nitrogen compound metabolic process
1.34 1.10e-20 GO:0043412 macromolecule modification
1.60 1.91e-20 GO:0007167 enzyme linked receptor protein signaling pathway
1.27 2.10e-20 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 5.68e-20 GO:0009059 macromolecule biosynthetic process
1.23 1.00e-19 GO:0051179 localization
1.36 1.01e-19 GO:0034645 cellular macromolecule biosynthetic process
1.25 2.12e-19 GO:0019538 protein metabolic process
1.21 6.15e-19 GO:0051716 cellular response to stimulus
1.65 6.86e-19 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.23 7.41e-19 GO:0007165 signal transduction
1.35 3.08e-18 GO:0023051 regulation of signaling
1.29 5.88e-18 GO:0042221 response to chemical stimulus
1.36 1.37e-17 GO:0007399 nervous system development
1.24 1.66e-17 GO:0051234 establishment of localization
1.48 1.82e-17 GO:0006351 transcription, DNA-dependent
1.24 4.37e-17 GO:0006810 transport
1.45 6.55e-17 GO:0032774 RNA biosynthetic process
1.42 8.88e-17 GO:0051246 regulation of protein metabolic process
1.31 1.78e-16 GO:0010467 gene expression
1.32 1.94e-16 GO:0016070 RNA metabolic process
1.29 3.29e-16 GO:0030154 cell differentiation
1.35 3.67e-16 GO:0009653 anatomical structure morphogenesis
1.45 5.30e-16 GO:0031324 negative regulation of cellular metabolic process
1.25 5.48e-16 GO:0009889 regulation of biosynthetic process
1.25 5.62e-16 GO:0031326 regulation of cellular biosynthetic process
1.43 6.02e-16 GO:0009892 negative regulation of metabolic process
1.43 6.86e-16 GO:0006793 phosphorus metabolic process
1.43 6.86e-16 GO:0006796 phosphate metabolic process
1.28 8.90e-16 GO:0048869 cellular developmental process
1.26 1.38e-15 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.25 1.52e-15 GO:0010468 regulation of gene expression
1.27 2.10e-15 GO:0090304 nucleic acid metabolic process
1.44 2.99e-15 GO:0022008 neurogenesis
1.37 4.11e-15 GO:0009893 positive regulation of metabolic process
1.44 5.06e-15 GO:0048468 cell development
1.25 5.92e-15 GO:0010556 regulation of macromolecule biosynthetic process
1.41 6.34e-15 GO:0032268 regulation of cellular protein metabolic process
1.24 8.94e-15 GO:0051171 regulation of nitrogen compound metabolic process
1.50 1.75e-14 GO:0010628 positive regulation of gene expression
1.38 1.80e-14 GO:0010604 positive regulation of macromolecule metabolic process
1.43 2.05e-14 GO:0010605 negative regulation of macromolecule metabolic process
1.37 4.78e-14 GO:0031325 positive regulation of cellular metabolic process
1.33 6.18e-14 GO:0009966 regulation of signal transduction
1.23 7.09e-14 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51 1.12e-13 GO:0045893 positive regulation of transcription, DNA-dependent
1.44 1.30e-13 GO:0016310 phosphorylation
1.43 1.50e-13 GO:0048699 generation of neurons
1.49 2.11e-13 GO:0031327 negative regulation of cellular biosynthetic process
1.46 2.50e-13 GO:0006468 protein phosphorylation
1.48 2.65e-13 GO:0009890 negative regulation of biosynthetic process
1.48 2.65e-13 GO:0030182 neuron differentiation
1.34 2.86e-13 GO:0035556 intracellular signal transduction
1.46 4.98e-13 GO:0010557 positive regulation of macromolecule biosynthetic process
1.50 8.80e-13 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.24 2.31e-12 GO:0051252 regulation of RNA metabolic process
1.49 2.31e-12 GO:0051172 negative regulation of nitrogen compound metabolic process
1.31 2.50e-12 GO:0065009 regulation of molecular function
1.49 2.51e-12 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47 3.57e-12 GO:0051254 positive regulation of RNA metabolic process
1.42 5.59e-12 GO:0051128 regulation of cellular component organization
1.47 5.73e-12 GO:0010558 negative regulation of macromolecule biosynthetic process
1.44 6.13e-12 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 7.55e-12 GO:0048583 regulation of response to stimulus
1.58 8.16e-12 GO:0048667 cell morphogenesis involved in neuron differentiation
1.51 1.07e-11 GO:0051253 negative regulation of RNA metabolic process
1.56 1.80e-11 GO:0048812 neuron projection morphogenesis
1.41 1.85e-11 GO:0031328 positive regulation of cellular biosynthetic process
1.58 1.91e-11 GO:0007409 axonogenesis
1.51 2.00e-11 GO:0045892 negative regulation of transcription, DNA-dependent
1.40 2.04e-11 GO:0009891 positive regulation of biosynthetic process
1.53 3.07e-11 GO:0031175 neuron projection development
1.48 3.40e-11 GO:0010629 negative regulation of gene expression
1.39 3.56e-11 GO:0008219 cell death
1.24 3.60e-11 GO:0006355 regulation of transcription, DNA-dependent
1.32 4.40e-11 GO:0010033 response to organic substance
1.39 4.98e-11 GO:0016265 death
1.41 5.14e-11 GO:0051173 positive regulation of nitrogen compound metabolic process
1.32 5.30e-11 GO:0051641 cellular localization
1.26 5.42e-11 GO:0048513 organ development
1.24 5.87e-11 GO:0065008 regulation of biological quality
1.35 6.16e-11 GO:0010646 regulation of cell communication
1.48 8.60e-11 GO:0048666 neuron development
1.34 1.57e-10 GO:0051649 establishment of localization in cell
1.52 2.72e-10 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.41 2.84e-10 GO:0016192 vesicle-mediated transport
1.51 2.87e-10 GO:0019226 transmission of nerve impulse
1.51 2.87e-10 GO:0035637 multicellular organismal signaling
1.51 3.03e-10 GO:0000904 cell morphogenesis involved in differentiation
1.31 3.17e-10 GO:0051239 regulation of multicellular organismal process
1.40 4.29e-10 GO:0031399 regulation of protein modification process
1.54 6.73e-10 GO:0032583 regulation of gene-specific transcription
1.49 1.18e-09 GO:0032990 cell part morphogenesis
1.35 1.81e-09 GO:0042127 regulation of cell proliferation
1.60 2.04e-09 GO:0007411 axon guidance
1.34 2.75e-09 GO:0032879 regulation of localization
1.48 3.04e-09 GO:0048858 cell projection morphogenesis
1.35 3.98e-09 GO:0050793 regulation of developmental process
1.24 4.06e-09 GO:0007166 cell surface receptor linked signaling pathway
1.52 4.13e-09 GO:0007268 synaptic transmission
1.42 4.79e-09 GO:0030030 cell projection organization
1.33 5.07e-09 GO:0007154 cell communication
1.41 6.11e-09 GO:0009719 response to endogenous stimulus
1.38 7.38e-09 GO:0007267 cell-cell signaling
1.37 1.46e-08 GO:0046907 intracellular transport
1.12 2.04e-08 GO:0032501 multicellular organismal process
1.41 2.07e-08 GO:0001932 regulation of protein phosphorylation
1.42 2.65e-08 GO:0009725 response to hormone stimulus
1.39 3.43e-08 GO:0019220 regulation of phosphate metabolic process
1.39 3.43e-08 GO:0051174 regulation of phosphorus metabolic process
1.23 5.64e-08 GO:0044281 small molecule metabolic process
1.39 5.67e-08 GO:0042325 regulation of phosphorylation
1.25 5.79e-08 GO:0006996 organelle organization
1.27 8.65e-08 GO:0033036 macromolecule localization
1.40 8.69e-08 GO:0032989 cellular component morphogenesis
1.49 9.68e-08 GO:0007243 intracellular protein kinase cascade
1.49 9.68e-08 GO:0023014 signal transduction via phosphorylation event
1.41 1.13e-07 GO:0000902 cell morphogenesis
1.45 1.63e-07 GO:0043549 regulation of kinase activity
1.52 2.12e-07 GO:0044419 interspecies interaction between organisms
1.66 2.13e-07 GO:0048011 nerve growth factor receptor signaling pathway
1.52 2.89e-07 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.36 3.13e-07 GO:2000026 regulation of multicellular organismal development
1.28 3.38e-07 GO:0050790 regulation of catalytic activity
1.43 4.17e-07 GO:0051338 regulation of transferase activity
1.37 7.29e-07 GO:0045595 regulation of cell differentiation
1.29 8.46e-07 GO:0043067 regulation of programmed cell death
1.44 9.36e-07 GO:0045859 regulation of protein kinase activity
1.35 9.94e-07 GO:0012501 programmed cell death
1.45 1.14e-06 GO:0051094 positive regulation of developmental process
1.29 1.14e-06 GO:0010941 regulation of cell death
1.52 1.26e-06 GO:0043434 response to peptide hormone stimulus
1.30 1.57e-06 GO:0009605 response to external stimulus
1.44 2.48e-06 GO:0061024 membrane organization
1.44 2.80e-06 GO:0016044 cellular membrane organization
1.28 3.10e-06 GO:0042981 regulation of apoptosis
1.28 3.21e-06 GO:0008104 protein localization
1.59 3.29e-06 GO:0000165 MAPKKK cascade
1.18 4.42e-06 GO:0006950 response to stress
1.35 5.08e-06 GO:0009790 embryo development
1.49 5.87e-06 GO:0018193 peptidyl-amino acid modification
1.34 8.09e-06 GO:0006915 apoptosis
1.51 9.53e-06 GO:0022603 regulation of anatomical structure morphogenesis
1.47 9.82e-06 GO:0016568 chromatin modification
1.09 1.23e-05 GO:0050896 response to stimulus
1.41 1.25e-05 GO:0072358 cardiovascular system development
1.41 1.25e-05 GO:0072359 circulatory system development
1.55 1.44e-05 GO:0008361 regulation of cell size
1.30 2.18e-05 GO:0040011 locomotion
1.39 3.08e-05 GO:0048585 negative regulation of response to stimulus
1.50 3.63e-05 GO:0006366 transcription from RNA polymerase II promoter
1.49 3.70e-05 GO:0033674 positive regulation of kinase activity
1.29 4.20e-05 GO:0015031 protein transport
1.40 4.63e-05 GO:0006066 alcohol metabolic process
1.29 4.81e-05 GO:0045184 establishment of protein localization
1.47 5.46e-05 GO:0071495 cellular response to endogenous stimulus
1.35 5.70e-05 GO:0009887 organ morphogenesis
1.49 5.78e-05 GO:0051130 positive regulation of cellular component organization
1.47 5.98e-05 GO:0051347 positive regulation of transferase activity
1.47 6.17e-05 GO:0032535 regulation of cellular component size
1.48 6.53e-05 GO:0060284 regulation of cell development
1.38 6.63e-05 GO:0007417 central nervous system development
1.49 6.83e-05 GO:0045860 positive regulation of protein kinase activity
1.48 7.11e-05 GO:0032870 cellular response to hormone stimulus
1.39 7.34e-05 GO:0048646 anatomical structure formation involved in morphogenesis
1.40 8.45e-05 GO:0010648 negative regulation of cell communication
1.42 8.49e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.24 8.50e-05 GO:0044248 cellular catabolic process
1.42 8.55e-05 GO:0009968 negative regulation of signal transduction
1.37 9.08e-05 GO:0043068 positive regulation of programmed cell death
1.44 9.27e-05 GO:0090066 regulation of anatomical structure size
1.46 1.06e-04 GO:0045597 positive regulation of cell differentiation
1.31 1.15e-04 GO:0051049 regulation of transport
1.29 1.20e-04 GO:0033554 cellular response to stress
1.37 1.42e-04 GO:0043065 positive regulation of apoptosis
1.81 1.45e-04 GO:0010720 positive regulation of cell development
1.33 1.46e-04 GO:0071310 cellular response to organic substance
1.29 1.46e-04 GO:0044093 positive regulation of molecular function
1.55 1.52e-04 GO:0032868 response to insulin stimulus
1.40 1.55e-04 GO:0040008 regulation of growth
1.56 1.62e-04 GO:0043193 positive regulation of gene-specific transcription
1.61 1.63e-04 GO:0014070 response to organic cyclic compound
1.36 1.67e-04 GO:0010942 positive regulation of cell death
1.50 1.79e-04 GO:0001568 blood vessel development
1.49 2.06e-04 GO:0071900 regulation of protein serine/threonine kinase activity
1.39 2.13e-04 GO:0023057 negative regulation of signaling
1.21 2.28e-04 GO:0009056 catabolic process
1.67 2.77e-04 GO:0007568 aging
1.33 2.81e-04 GO:0051276 chromosome organization
1.65 3.34e-04 GO:0001666 response to hypoxia
1.76 3.35e-04 GO:0031098 stress-activated protein kinase signaling cascade
2.48 3.61e-04 GO:0048639 positive regulation of developmental growth
1.77 3.67e-04 GO:0030308 negative regulation of cell growth
1.39 3.88e-04 GO:0008285 negative regulation of cell proliferation
1.62 4.64e-04 GO:0070482 response to oxygen levels
1.38 5.38e-04 GO:0072521 purine-containing compound metabolic process
1.44 5.57e-04 GO:0051098 regulation of binding
1.51 5.76e-04 GO:0001558 regulation of cell growth
1.35 6.50e-04 GO:0008284 positive regulation of cell proliferation
1.22 6.87e-04 GO:0044085 cellular component biogenesis
1.93 7.13e-04 GO:0048638 regulation of developmental growth
1.31 8.98e-04 GO:0051726 regulation of cell cycle
1.24 9.30e-04 GO:0022607 cellular component assembly
1.55 1.06e-03 GO:0032582 negative regulation of gene-specific transcription
1.71 1.11e-03 GO:0090276 regulation of peptide hormone secretion
1.29 1.15e-03 GO:0043085 positive regulation of catalytic activity
1.37 1.16e-03 GO:0060341 regulation of cellular localization
1.71 1.23e-03 GO:0045792 negative regulation of cell size
1.72 1.51e-03 GO:0050796 regulation of insulin secretion
1.57 1.56e-03 GO:0032869 cellular response to insulin stimulus
2.00 1.67e-03 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.33 1.82e-03 GO:0006935 chemotaxis
1.33 1.82e-03 GO:0042330 taxis
1.65 1.83e-03 GO:0008286 insulin receptor signaling pathway
1.47 2.01e-03 GO:0051248 negative regulation of protein metabolic process
1.56 2.19e-03 GO:0016569 covalent chromatin modification
1.24 2.23e-03 GO:0070887 cellular response to chemical stimulus
1.50 2.47e-03 GO:0071375 cellular response to peptide hormone stimulus
1.35 2.50e-03 GO:0008283 cell proliferation
1.68 2.65e-03 GO:0002791 regulation of peptide secretion
1.68 2.65e-03 GO:0090087 regulation of peptide transport
1.32 2.78e-03 GO:0044092 negative regulation of molecular function
1.45 2.91e-03 GO:0010608 posttranscriptional regulation of gene expression
1.37 2.99e-03 GO:0051247 positive regulation of protein metabolic process
1.57 3.21e-03 GO:0006417 regulation of translation
1.55 3.90e-03 GO:0016570 histone modification
1.77 3.98e-03 GO:0001505 regulation of neurotransmitter levels
1.51 4.09e-03 GO:0043405 regulation of MAP kinase activity
1.61 4.60e-03 GO:0045926 negative regulation of growth
1.58 4.61e-03 GO:0006813 potassium ion transport
1.74 5.33e-03 GO:0046328 regulation of JNK cascade
1.43 5.49e-03 GO:0051960 regulation of nervous system development
1.40 5.55e-03 GO:0044057 regulation of system process
1.33 5.63e-03 GO:0006325 chromatin organization
1.80 6.14e-03 GO:0050769 positive regulation of neurogenesis
1.71 6.21e-03 GO:0070302 regulation of stress-activated protein kinase signaling cascade
1.55 6.34e-03 GO:0071902 positive regulation of protein serine/threonine kinase activity
1.68 6.96e-03 GO:0007611 learning or memory
1.51 7.07e-03 GO:0044087 regulation of cellular component biogenesis
1.52 7.09e-03 GO:0019318 hexose metabolic process
1.46 7.24e-03 GO:0032269 negative regulation of cellular protein metabolic process
1.42 8.06e-03 GO:0001944 vasculature development
1.36 8.24e-03 GO:0006163 purine nucleotide metabolic process
1.29 9.33e-03 GO:0006812 cation transport
1.48 9.56e-03 GO:0005996 monosaccharide metabolic process
1.64 1.00e-02 GO:0050890 cognition
1.36 1.04e-02 GO:0032270 positive regulation of cellular protein metabolic process
1.36 1.14e-02 GO:0007264 small GTPase mediated signal transduction
1.38 1.24e-02 GO:0015672 monovalent inorganic cation transport
1.74 1.26e-02 GO:0030330 DNA damage response, signal transduction by p53 class mediator
1.32 1.28e-02 GO:0009628 response to abiotic stimulus
1.37 1.45e-02 GO:0012502 induction of programmed cell death
1.36 1.49e-02 GO:0009792 embryo development ending in birth or egg hatching
1.34 1.52e-02 GO:0016477 cell migration
1.23 1.58e-02 GO:0009888 tissue development
1.31 1.59e-02 GO:0030001 metal ion transport
1.56 1.89e-02 GO:0045165 cell fate commitment
1.54 1.99e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.36 2.01e-02 GO:0006917 induction of apoptosis
1.87 2.08e-02 GO:0043279 response to alkaloid
1.56 2.13e-02 GO:0046883 regulation of hormone secretion
1.43 2.32e-02 GO:0050767 regulation of neurogenesis
1.39 2.33e-02 GO:0009199 ribonucleoside triphosphate metabolic process
1.49 2.36e-02 GO:0043408 regulation of MAPKKK cascade
1.30 2.45e-02 GO:0080134 regulation of response to stress
1.38 2.54e-02 GO:0007610 behavior
1.44 2.59e-02 GO:0007507 heart development
1.80 2.63e-02 GO:0031346 positive regulation of cell projection organization
1.56 2.72e-02 GO:0043406 positive regulation of MAP kinase activity
1.74 2.99e-02 GO:0018205 peptidyl-lysine modification
1.29 3.01e-02 GO:0016071 mRNA metabolic process
1.41 3.01e-02 GO:0051101 regulation of DNA binding
1.51 3.09e-02 GO:0030900 forebrain development
1.34 3.16e-02 GO:0010627 regulation of intracellular protein kinase cascade
1.39 3.28e-02 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.39 3.32e-02 GO:0051270 regulation of cellular component movement
1.48 3.55e-02 GO:0034220 ion transmembrane transport
1.38 3.65e-02 GO:0009144 purine nucleoside triphosphate metabolic process
1.44 3.72e-02 GO:0051129 negative regulation of cellular component organization
1.64 3.73e-02 GO:0006836 neurotransmitter transport
1.28 3.86e-02 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.24 3.89e-02 GO:0071844 cellular component assembly at cellular level
1.29 4.21e-02 GO:0034613 cellular protein localization
1.62 4.37e-02 GO:0042770 signal transduction in response to DNA damage
1.60 4.47e-02 GO:0007265 Ras protein signal transduction
1.29 4.48e-02 GO:0070727 cellular macromolecule localization
1.78 4.78e-02 GO:0050770 regulation of axonogenesis
1.37 4.95e-02 GO:0031401 positive regulation of protein modification process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 4.61e-67 GO:0044424 intracellular part
1.14 3.07e-64 GO:0005622 intracellular
1.19 2.76e-57 GO:0005737 cytoplasm
1.16 1.22e-42 GO:0043227 membrane-bounded organelle
1.16 4.88e-42 GO:0043231 intracellular membrane-bounded organelle
1.14 5.76e-42 GO:0043226 organelle
1.14 3.28e-41 GO:0043229 intracellular organelle
1.21 7.78e-39 GO:0044444 cytoplasmic part
1.36 7.49e-28 GO:0005829 cytosol
1.19 1.89e-26 GO:0005634 nucleus
1.18 1.44e-24 GO:0044446 intracellular organelle part
1.18 1.62e-24 GO:0044422 organelle part
1.05 1.53e-22 GO:0005623 cell
1.31 2.06e-22 GO:0070013 intracellular organelle lumen
1.05 2.22e-22 GO:0044464 cell part
1.30 5.16e-22 GO:0043233 organelle lumen
1.30 5.63e-22 GO:0031974 membrane-enclosed lumen
1.31 7.29e-21 GO:0044428 nuclear part
1.32 2.06e-19 GO:0031981 nuclear lumen
1.38 3.91e-18 GO:0005654 nucleoplasm
1.20 5.77e-16 GO:0032991 macromolecular complex
1.21 3.04e-14 GO:0043234 protein complex
1.38 1.72e-09 GO:0044451 nucleoplasm part
1.48 5.64e-08 GO:0043005 neuron projection
1.19 9.05e-08 GO:0044459 plasma membrane part
1.27 2.11e-07 GO:0000267 cell fraction
1.23 2.26e-07 GO:0012505 endomembrane system
1.19 5.39e-07 GO:0031090 organelle membrane
1.29 3.64e-06 GO:0005626 insoluble fraction
1.29 7.05e-06 GO:0005624 membrane fraction
1.26 1.22e-05 GO:0005794 Golgi apparatus
1.60 3.03e-05 GO:0030424 axon
1.53 3.71e-05 GO:0016604 nuclear body
1.28 5.13e-05 GO:0031410 cytoplasmic vesicle
1.14 6.65e-05 GO:0043228 non-membrane-bounded organelle
1.14 6.65e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.27 7.99e-05 GO:0031982 vesicle
1.28 1.07e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.28 1.57e-04 GO:0031988 membrane-bounded vesicle
1.64 2.11e-04 GO:0034703 cation channel complex
1.31 2.61e-04 GO:0005694 chromosome
1.39 2.70e-04 GO:0048471 perinuclear region of cytoplasm
1.30 3.28e-04 GO:0044431 Golgi apparatus part
1.20 4.44e-04 GO:0005887 integral to plasma membrane
1.20 4.48e-04 GO:0031226 intrinsic to plasma membrane
1.71 2.36e-03 GO:0016585 chromatin remodeling complex
2.27 2.88e-03 GO:0034704 calcium channel complex
1.45 3.14e-03 GO:0000228 nuclear chromosome
1.66 4.03e-03 GO:0005925 focal adhesion
2.30 5.64e-03 GO:0005881 cytoplasmic microtubule
2.42 8.54e-03 GO:0005891 voltage-gated calcium channel complex
1.88 1.40e-02 GO:0005905 coated pit
1.28 1.64e-02 GO:0000139 Golgi membrane
1.18 1.91e-02 GO:0005783 endoplasmic reticulum
1.41 2.33e-02 GO:0034702 ion channel complex
1.58 2.74e-02 GO:0005924 cell-substrate adherens junction
1.71 2.85e-02 GO:0042383 sarcolemma
1.16 3.58e-02 GO:0005739 mitochondrion
1.44 3.62e-02 GO:0044454 nuclear chromosome part
1.29 3.77e-02 GO:0045202 synapse
1.27 4.29e-02 GO:0044427 chromosomal part
1.55 4.83e-02 GO:0030055 cell-substrate junction
1.62 4.95e-02 GO:0008076 voltage-gated potassium channel complex
1.62 4.95e-02 GO:0034705 potassium channel complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.27 7.48e-86 GO:0005515 protein binding
1.12 5.14e-56 GO:0005488 binding
1.53 1.41e-17 GO:0043565 sequence-specific DNA binding
1.48 2.41e-16 GO:0019899 enzyme binding
1.41 3.29e-15 GO:0001071 nucleic acid binding transcription factor activity
1.41 3.29e-15 GO:0003700 sequence-specific DNA binding transcription factor activity
1.38 2.05e-13 GO:0030528 transcription regulator activity
1.45 2.27e-13 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.23 5.44e-12 GO:0000166 nucleotide binding
1.41 6.93e-12 GO:0016301 kinase activity
1.13 6.26e-11 GO:0003824 catalytic activity
1.36 1.23e-10 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.44 2.11e-10 GO:0004672 protein kinase activity
1.25 3.29e-10 GO:0016740 transferase activity
1.55 4.61e-10 GO:0000988 protein binding transcription factor activity
1.55 4.61e-10 GO:0000989 transcription factor binding transcription factor activity
1.23 6.59e-10 GO:0017076 purine nucleotide binding
1.55 7.23e-10 GO:0003712 transcription cofactor activity
1.23 1.57e-09 GO:0032553 ribonucleotide binding
1.23 1.57e-09 GO:0032555 purine ribonucleotide binding
1.23 2.57e-09 GO:0035639 purine ribonucleoside triphosphate binding
1.59 7.22e-09 GO:0008134 transcription factor binding
1.25 8.37e-09 GO:0030554 adenyl nucleotide binding
1.25 1.84e-08 GO:0032559 adenyl ribonucleotide binding
1.47 1.89e-08 GO:0019904 protein domain specific binding
1.56 2.20e-08 GO:0016563 transcription activator activity
1.47 2.42e-08 GO:0004674 protein serine/threonine kinase activity
1.24 5.49e-08 GO:0005524 ATP binding
1.67 2.49e-07 GO:0010843 promoter binding
1.63 9.85e-07 GO:0000975 regulatory region DNA binding
1.63 9.85e-07 GO:0001067 regulatory region nucleic acid binding
1.63 9.85e-07 GO:0044212 transcription regulatory region DNA binding
1.37 1.63e-06 GO:0008324 cation transmembrane transporter activity
1.71 5.43e-06 GO:0003714 transcription corepressor activity
1.14 6.84e-06 GO:0003676 nucleic acid binding
1.51 1.43e-05 GO:0005261 cation channel activity
1.54 2.29e-05 GO:0019900 kinase binding
1.67 7.16e-05 GO:0022843 voltage-gated cation channel activity
2.11 1.05e-04 GO:0003707 steroid hormone receptor activity
1.54 1.81e-04 GO:0019901 protein kinase binding
2.05 2.35e-04 GO:0004879 ligand-dependent nuclear receptor activity
1.23 3.02e-04 GO:0022892 substrate-specific transporter activity
1.47 3.55e-04 GO:0003702 RNA polymerase II transcription factor activity
1.34 5.47e-04 GO:0030695 GTPase regulator activity
1.33 7.58e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.28 8.96e-04 GO:0046983 protein dimerization activity
1.52 1.11e-03 GO:0005244 voltage-gated ion channel activity
1.52 1.11e-03 GO:0022832 voltage-gated channel activity
2.42 1.56e-03 GO:0005245 voltage-gated calcium channel activity
1.51 1.70e-03 GO:0003682 chromatin binding
1.26 1.83e-03 GO:0015075 ion transmembrane transporter activity
1.14 2.48e-03 GO:0003677 DNA binding
1.46 2.93e-03 GO:0003713 transcription coactivator activity
1.79 3.23e-03 GO:0005262 calcium channel activity
1.25 3.39e-03 GO:0042802 identical protein binding
1.23 4.15e-03 GO:0003723 RNA binding
1.41 4.77e-03 GO:0032403 protein complex binding
1.49 5.32e-03 GO:0043566 structure-specific DNA binding
1.19 5.60e-03 GO:0005215 transporter activity
1.39 6.58e-03 GO:0005083 small GTPase regulator activity
1.56 7.84e-03 GO:0004713 protein tyrosine kinase activity
1.22 1.03e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.37 1.09e-02 GO:0016564 transcription repressor activity
1.65 1.20e-02 GO:0005057 receptor signaling protein activity
1.31 1.36e-02 GO:0015267 channel activity
1.21 1.38e-02 GO:0022857 transmembrane transporter activity
1.32 1.41e-02 GO:0005216 ion channel activity
1.31 1.62e-02 GO:0022803 passive transmembrane transporter activity
1.63 2.01e-02 GO:0051427 hormone receptor binding
1.35 2.28e-02 GO:0022836 gated channel activity
1.71 2.39e-02 GO:0031625 ubiquitin protein ligase binding
1.31 2.59e-02 GO:0022838 substrate-specific channel activity
1.55 3.18e-02 GO:0005267 potassium channel activity
1.26 3.27e-02 GO:0008092 cytoskeletal protein binding
1.58 3.79e-02 GO:0017124 SH3 domain binding