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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: MTF1.p2

Z-value: 3.527

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_-_101459410	72.523
chr5_-_11904127	68.544		CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr16_+_58497548	63.712	NM_020465	NDRG4	NDRG family member 4
chr7_+_64498643	63.413		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr16_+_56659679	57.084		MT1E	metallothionein 1E
chr1_+_104068312	54.397		RNPC3	RNA-binding region (RNP1, RRM) containing 3
chr16_+_56659584	54.147	NM_175617	MT1E	metallothionein 1E
chr5_-_11903964	53.820	NM_001332	CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr16_+_58497628	44.828		NDRG4	NDRG family member 4
chr16_+_56703725	44.306	NM_005951	MT1H	metallothionein 1H
chr1_-_32229635	41.177	NM_001703	BAI2	brain-specific angiogenesis inhibitor 2
chr10_+_124220990	38.777	NM_002775	HTRA1	HtrA serine peptidase 1
chr16_+_58497993	38.529	NM_001130487	NDRG4	NDRG family member 4
chr16_+_56623266	37.837	NM_005954	MT3	metallothionein 3
chr20_-_3154169	37.260		ProSAPiP1	ProSAPiP1 protein
chr19_+_33685489	36.157	NM_002333	LRP3	low density lipoprotein receptor-related protein 3
chr9_-_139922705	35.089	NM_001606	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr15_-_29862926	34.857	NM_015307	FAM189A1	family with sequence similarity 189, member A1
chr7_-_994008	34.560		ADAP1	ArfGAP with dual PH domains 1
chr16_+_56666533	33.748	NM_176870	MT1M	metallothionein 1M
chr7_-_44365019	33.704	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr6_+_89855745	31.327	NM_001010853	PM20D2	peptidase M20 domain containing 2
chr9_+_133320247	31.251		ASS1	argininosuccinate synthase 1
chr16_+_56642477	30.917	NM_005953	MT2A	metallothionein 2A
chr13_+_27131799	30.733	NM_006646	WASF3	WAS protein family, member 3
chr4_+_187112936	30.494		CYP4V2	cytochrome P450, family 4, subfamily V, polypeptide 2
chr20_+_20348744	30.234	NM_002196	INSM1	insulinoma-associated 1
chr11_+_125774271	30.142	NM_013264	DDX25	DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr8_-_110704019	29.999	NM_001099743 NM_001099744	SYBU	syntabulin (syntaxin-interacting)
chr9_-_139922595	29.630		ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr6_+_35227234	29.579		ZNF76	zinc finger protein 76
chr19_-_5340700	28.953	NM_002850 NM_130853 NM_130854 NM_130855	PTPRS	protein tyrosine phosphatase, receptor type, S
chr2_-_97303983	28.605		KANSL3	KAT8 regulatory NSL complex subunit 3
chr14_-_81687574	28.457	NM_201595	GTF2A1	general transcription factor IIA, 1, 19/37kDa
chr19_+_33685140	28.018		LRP3	low density lipoprotein receptor-related protein 3
chr12_+_48499655	27.533	NM_001166686	PFKM	phosphofructokinase, muscle
chr9_+_133320093	27.372	NM_000050 NM_054012	ASS1	argininosuccinate synthase 1
chr19_-_36523540	27.335	NM_001199570	CLIP3	CAP-GLY domain containing linker protein 3
chr7_+_86273951	27.309		GRM3	glutamate receptor, metabotropic 3
chr11_-_12030128	26.686	NM_001018057	DKK3	dickkopf 3 homolog (Xenopus laevis)
chr13_-_80915041	26.679	NM_005842	SPRY2	sprouty homolog 2 (Drosophila)
chr14_-_81687265	26.602	NM_015859	GTF2A1	general transcription factor IIA, 1, 19/37kDa
chr2_+_20646831	26.543	NM_004040	RHOB	ras homolog gene family, member B
chr17_-_5404304	25.929	NM_001162371	LOC728392	uncharacterized LOC728392
chr10_-_118501981	25.896	NM_025015	HSPA12A	heat shock 70kDa protein 12A
chr16_-_56701904	25.688	NM_005950	MT1G	metallothionein 1G
chr9_+_34958320	25.683		KIAA1045	KIAA1045
chr16_+_56716378	25.185	NM_005952	MT1X	metallothionein 1X
chr12_-_45270157	24.812	NM_001145108 NM_006159	NELL2	NEL-like 2 (chicken)
chr19_-_36523770	24.634	NM_015526	CLIP3	CAP-GLY domain containing linker protein 3
chr1_-_184723952	24.543		EDEM3	ER degradation enhancer, mannosidase alpha-like 3
chr8_+_136469557	24.434	NM_006558	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3
chr3_-_183543295	24.406	NM_024871	MAP6D1	MAP6 domain containing 1
chrX_-_13956445	24.280
chr15_+_101459459	24.039	NM_024652	LRRK1	leucine-rich repeat kinase 1
chr16_+_56691854	23.713	NM_005949	MT1F	metallothionein 1F
chr2_+_236403290	23.575		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr3_+_71803200	23.509	NM_018971	GPR27	G protein-coupled receptor 27
chr15_+_80696569	23.090	NM_014862	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr14_+_96505566	23.076	NM_001252507	C14orf132	chromosome 14 open reading frame 132
chr6_+_7590405	22.884	NM_152551	SNRNP48	small nuclear ribonucleoprotein 48kDa (U11/U12)
chr7_+_86274076	22.696		GRM3	glutamate receptor, metabotropic 3
chr9_+_137979513	22.392		OLFM1	olfactomedin 1
chr7_-_994259	22.367	NM_006869	ADAP1	ArfGAP with dual PH domains 1
chr20_-_62130390	22.292	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr19_-_49944613	22.241	NM_020309	SLC17A7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr2_-_97304060	22.147		KANSL3	KAT8 regulatory NSL complex subunit 3
chr20_-_55841090	21.802		BMP7	bone morphogenetic protein 7
chr3_+_133465098	21.721		TF	transferrin
chrX_-_102319080	21.412		BEX1	brain expressed, X-linked 1
chr16_+_56225301	21.325		GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr22_+_19701968	21.320	NM_002688	SEPT5	septin 5
chr4_-_109684053	21.200	NM_001146590 NM_001146627 NM_031279	AGXT2L1	alanine-glyoxylate aminotransferase 2-like 1
chr7_+_86273867	21.162		GRM3	glutamate receptor, metabotropic 3
chr11_-_2906960	21.119	NM_000076 NM_001122630 NM_001122631	CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr16_+_84002099	21.029	NM_019065	NECAB2	N-terminal EF-hand calcium binding protein 2
chrX_-_102319096	20.611	NM_018476	BEX1	brain expressed, X-linked 1
chr2_-_97304080	20.600	NM_001115016 NM_017991	KANSL3	KAT8 regulatory NSL complex subunit 3
chr8_-_121824268	20.488		SNTB1	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr2_+_170590454	20.478		KLHL23	kelch-like 23 (Drosophila)
chrX_+_135229536	20.473	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr8_-_121824287	20.454	NM_021021	SNTB1	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr9_+_34958171	20.403	NM_015297	KIAA1045	KIAA1045
chr1_-_241520384	20.312		RGS7	regulator of G-protein signaling 7
chr15_+_76352323	20.249		C15orf27	chromosome 15 open reading frame 27
chr15_+_74422920	20.219		ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chr12_-_54982271	20.180	NM_006741	PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr8_-_121824015	20.173
chr12_+_57610577	20.095	NM_007224	NXPH4	neurexophilin 4
chr19_+_708766	20.018	NM_001040134 NM_002579	PALM	paralemmin
chr3_-_52001388	19.977	NM_020418 NM_001174100 NM_033008	PCBP4	poly(rC) binding protein 4
chr6_+_35227478	19.835	NM_003427	ZNF76	zinc finger protein 76
chr18_-_5543967	19.785	NM_012307	EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr22_+_38035718	19.647		SH3BP1	SH3-domain binding protein 1
chr22_+_51039178	19.565		MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2
chr6_+_7108864	19.453		RREB1	ras responsive element binding protein 1
chr20_+_34742656	19.335	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr1_-_201476248	19.323	NM_001193570 NM_004078	CSRP1	cysteine and glycine-rich protein 1
chr15_+_74422742	19.293	NM_020851	ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chr7_-_158622184	19.272		ESYT2	extended synaptotagmin-like protein 2
chr19_+_38755097	19.187	NM_001166103 NM_021102	SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr4_+_187112635	19.172	NM_207352	CYP4V2	cytochrome P450, family 4, subfamily V, polypeptide 2
chr3_+_133465250	19.153		TF	transferrin
chr16_+_56672577	19.018	NM_005946	MT1A	metallothionein 1A
chr19_+_40697516	19.016	NM_002446	MAP3K10	mitogen-activated protein kinase kinase kinase 10
chr4_+_187065994	18.998	NM_015398	FAM149A	family with sequence similarity 149, member A
chr10_-_61469322	18.944	NM_194298	LOC100129721 SLC16A9	uncharacterized LOC100129721 solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr12_-_45269953	18.926		NELL2	NEL-like 2 (chicken)
chr22_+_21986968	18.809	NM_152612	CCDC116	coiled-coil domain containing 116
chr8_-_26371387	18.790	NM_007257	PNMA2	paraneoplastic antigen MA2
chr17_+_30813928	18.694	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr8_+_26371461	18.688	NM_001197293	DPYSL2	dihydropyrimidinase-like 2
chr13_-_45150601	18.579	NM_001243799 NM_183422	TSC22D1	TSC22 domain family, member 1
chr12_+_112204690	18.546	NM_000690 NM_001204889	ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)
chr1_+_151254740	18.530	NM_020832	ZNF687	zinc finger protein 687
chr20_+_44034632	18.411	NM_001197139 NM_001048221 NM_001048222 NM_001197140 NM_018478	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr2_+_219824346	18.395	NM_003936	CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr9_+_140772228	18.368	NM_000718 NM_001243812	CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit
chr22_-_51021200	18.316		CHKB	choline kinase beta
chr13_-_29069215	18.264	NM_001159920 NM_001160030 NM_001160031 NM_002019	FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
chr19_-_57352055	18.216	NM_001146326 NM_001146327 NM_015363 NM_001146184 NM_001146185 NM_001146187 NM_006210	ZIM2 PEG3	zinc finger, imprinted 2 paternally expressed 3
chr9_+_137967401	18.196		OLFM1	olfactomedin 1
chr2_+_26915390	18.168	NM_002246	KCNK3	potassium channel, subfamily K, member 3
chr7_-_97881436	18.145	NM_015395	TECPR1	tectonin beta-propeller repeat containing 1
chr9_-_93405066	18.004	NM_017594	DIRAS2	DIRAS family, GTP-binding RAS-like 2
chr11_-_117747618	17.851	NM_001204268 NM_001243598 NM_001164832 NM_001164836 NM_001164837 NM_022003	FXYD6-FXYD2 FXYD6	FXYD6-FXYD2 readthrough FXYD domain containing ion transport regulator 6
chr3_+_133465204	17.811		TF	transferrin
chr17_-_71308118	17.806	NM_012121	CDC42EP4	CDC42 effector protein (Rho GTPase binding) 4
chr16_+_89894853	17.797	NM_032451	SPIRE2	spire homolog 2 (Drosophila)
chr18_-_21851816	17.787		OSBPL1A	oxysterol binding protein-like 1A
chr1_-_201476241	17.638		CSRP1	cysteine and glycine-rich protein 1
chr2_+_236402948	17.497		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr2_+_207308280	17.443	NM_003812	ADAM23	ADAM metallopeptidase domain 23
chr19_+_16222706	17.392		RAB8A	RAB8A, member RAS oncogene family
chr9_+_137967366	17.385		OLFM1	olfactomedin 1
chr1_-_11714738	17.340	NM_012168	FBXO2	F-box protein 2
chr3_-_10749715	17.162		ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr17_+_74733468	17.156	NM_001242532 NM_001242533 NM_001242535 NM_001242536 NM_001242537 NM_024311	MFSD11	major facilitator superfamily domain containing 11
chr2_+_241507928	17.155	NM_018226	RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1
chr1_-_201476218	17.110		CSRP1	cysteine and glycine-rich protein 1
chr22_-_29711474	17.038		RASL10A	RAS-like, family 10, member A
chrX_-_140271275	16.934		LDOC1	leucine zipper, down-regulated in cancer 1
chr17_-_37307814	16.917		PLXDC1	plexin domain containing 1
chr19_+_36266366	16.828	NM_001172630 NM_052948	ARHGAP33	Rho GTPase activating protein 33
chr19_-_42746743	16.805		GSK3A	glycogen synthase kinase 3 alpha
chr22_-_51021255	16.666		CHKB	choline kinase beta
chr22_+_26565623	16.658		SEZ6L	seizure related 6 homolog (mouse)-like
chr2_+_241938254	16.624	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr10_-_75634219	16.601	NM_001204492 NM_001222 NM_172169 NM_172170 NM_172171 NM_172173	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma
chr19_+_38893828	16.433		FAM98C	family with sequence similarity 98, member C
chr1_+_77747727	16.427		AK5	adenylate kinase 5
chr7_+_142552547	16.422	NM_004445	EPHB6	EPH receptor B6
chr5_+_65892139	16.387	NM_001164664 NM_198828	MAST4	microtubule associated serine/threonine kinase family member 4
chr11_+_45868956	16.384	NM_021117	CRY2	cryptochrome 2 (photolyase-like)
chr22_-_31741761	16.366		PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr4_+_3768104	16.350		ADRA2C	adrenergic, alpha-2C-, receptor
chr16_+_1203240	16.229	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr22_+_43808011	16.221	NM_001044370	MPPED1	metallophosphoesterase domain containing 1
chr1_+_4715104	16.215	NM_001042478 NM_018836	AJAP1	adherens junctions associated protein 1
chr6_-_46459010	16.176	NM_001251974	RCAN2	regulator of calcineurin 2
chr15_+_68871285	16.152	NM_006091	CORO2B	coronin, actin binding protein, 2B
chr13_-_36705432	15.957		DCLK1	doublecortin-like kinase 1
chr9_-_80646150	15.917	NM_002072	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide
chr4_-_5890142	15.902		CRMP1	collapsin response mediator protein 1
chr20_-_32274070	15.898		E2F1	E2F transcription factor 1
chr1_-_201475966	15.835	NM_001193571	CSRP1	cysteine and glycine-rich protein 1
chr12_-_93964636	15.809
chr7_-_158622202	15.779	NM_020728	ESYT2	extended synaptotagmin-like protein 2
chr2_-_224903933	15.671	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr1_+_1981902	15.601	NM_002744	PRKCZ	protein kinase C, zeta
chr9_+_130374466	15.570	NM_001032221 NM_003165	STXBP1	syntaxin binding protein 1
chr19_-_13617037	15.537	NM_000068 NM_001127221 NM_001127222 NM_001174080 NM_023035	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr7_+_4721722	15.534	NM_001037165	FOXK1	forkhead box K1
chrX_-_140271293	15.432	NM_012317	LDOC1	leucine zipper, down-regulated in cancer 1
chr19_+_35521591	15.428	NM_001037 NM_199037	SCN1B	sodium channel, voltage-gated, type I, beta
chr1_+_10270680	15.360	NM_015074 NM_183416	KIF1B	kinesin family member 1B
chr4_-_8873453	15.313	NM_018942	HMX1	H6 family homeobox 1
chr8_+_1711869	15.287	NM_018941	CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr4_-_5890266	15.118	NM_001313	CRMP1	collapsin response mediator protein 1
chr16_+_6069094	15.092	NM_001142333 NM_018723	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr20_-_590909	15.079	NM_004609	TCF15	transcription factor 15 (basic helix-loop-helix)
chr12_-_106532447	15.066		NUAK1	NUAK family, SNF1-like kinase, 1
chr17_-_1531543	15.063		SLC43A2	solute carrier family 43, member 2
chr1_-_57888785	15.061		DAB1	disabled homolog 1 (Drosophila)
chr8_-_121823696	15.033		SNTB1	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr19_-_9731883	14.933	NM_152289	ZNF561	zinc finger protein 561
chr16_+_2570322	14.909	NM_001145815 NM_015944	AMDHD2	amidohydrolase domain containing 2
chrX_-_8700170	14.855	NM_000216	KAL1	Kallmann syndrome 1 sequence
chr7_-_143059696	14.837	NM_001031690	FAM131B	family with sequence similarity 131, member B
chr7_+_29234325	14.766		CHN2	chimerin (chimaerin) 2
chr22_+_26565424	14.762	NM_001184773 NM_001184774 NM_001184775 NM_001184776 NM_001184777 NM_021115	SEZ6L	seizure related 6 homolog (mouse)-like
chr16_+_56225250	14.711	NM_020988 NM_138736	GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr14_+_100150596	14.694	NM_006668	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1
chr18_-_78005230	14.688	NM_032510	PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)
chr22_-_39548448	14.615	NM_175709	CBX7	chromobox homolog 7
chrX_-_47479229	14.553	NM_006950 NM_133499	SYN1	synapsin I
chr1_+_77747602	14.537	NM_174858	AK5	adenylate kinase 5
chr11_-_12030622	14.524	NM_015881	DKK3	dickkopf 3 homolog (Xenopus laevis)
chr19_-_42746678	14.524		GSK3A	glycogen synthase kinase 3 alpha
chr1_-_241520467	14.508	NM_002924	RGS7	regulator of G-protein signaling 7

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.82	1.88e-42	GO:0007399	nervous system development
1.52	1.95e-41	GO:0048856	anatomical structure development
1.54	6.02e-40	GO:0048731	system development
1.45	4.07e-39	GO:0032502	developmental process
1.46	1.12e-37	GO:0007275	multicellular organismal development
1.25	4.10e-37	GO:0065007	biological regulation
1.43	2.08e-35	GO:0023052	signaling
1.25	2.13e-33	GO:0050789	regulation of biological process
1.26	2.57e-33	GO:0050794	regulation of cellular process
1.15	1.13e-32	GO:0009987	cellular process
1.55	4.44e-28	GO:0048869	cellular developmental process
1.55	7.84e-28	GO:0030154	cell differentiation
1.66	3.36e-27	GO:0009653	anatomical structure morphogenesis
1.86	7.73e-27	GO:0022008	neurogenesis
1.87	6.78e-26	GO:0048699	generation of neurons
1.59	2.16e-24	GO:0023051	regulation of signaling
1.38	3.85e-24	GO:0007165	signal transduction
1.28	5.21e-23	GO:0032501	multicellular organismal process
1.91	4.23e-22	GO:0030182	neuron differentiation
1.64	7.60e-22	GO:0051239	regulation of multicellular organismal process
1.77	1.29e-21	GO:0048468	cell development
1.50	1.49e-20	GO:0048513	organ development
1.30	1.01e-19	GO:0051716	cellular response to stimulus
2.02	1.01e-19	GO:0007417	central nervous system development
1.72	9.42e-19	GO:0050793	regulation of developmental process
1.99	4.42e-18	GO:0000904	cell morphogenesis involved in differentiation
1.64	3.52e-17	GO:0010646	regulation of cell communication
1.89	3.76e-17	GO:0048666	neuron development
1.40	4.71e-17	GO:0048519	negative regulation of biological process
2.02	7.08e-17	GO:0048667	cell morphogenesis involved in neuron differentiation
1.42	1.17e-16	GO:0048523	negative regulation of cellular process
1.53	1.19e-16	GO:0009966	regulation of signal transduction
1.95	1.51e-16	GO:0019226	transmission of nerve impulse
1.95	1.51e-16	GO:0035637	multicellular organismal signaling
2.00	1.92e-16	GO:0048812	neuron projection morphogenesis
1.83	2.69e-16	GO:0032989	cellular component morphogenesis
2.02	5.58e-16	GO:0007409	axonogenesis
1.46	5.89e-16	GO:0007166	cell surface receptor linked signaling pathway
1.84	7.94e-16	GO:0000902	cell morphogenesis
1.92	1.23e-15	GO:0048858	cell projection morphogenesis
1.78	1.34e-15	GO:0045595	regulation of cell differentiation
1.99	1.45e-15	GO:0007268	synaptic transmission
1.92	2.61e-15	GO:0031175	neuron projection development
1.73	2.77e-15	GO:2000026	regulation of multicellular organismal development
1.90	3.41e-15	GO:0032990	cell part morphogenesis
1.79	8.78e-15	GO:0030030	cell projection organization
1.38	1.27e-14	GO:0042221	response to chemical stimulus
1.71	1.36e-14	GO:0007267	cell-cell signaling
1.42	2.86e-14	GO:0048583	regulation of response to stimulus
1.34	4.89e-14	GO:0048518	positive regulation of biological process
1.75	9.11e-14	GO:0007167	enzyme linked receptor protein signaling pathway
1.91	1.41e-13	GO:0051094	positive regulation of developmental process
2.02	1.52e-13	GO:0007420	brain development
1.58	2.31e-13	GO:0007154	cell communication
1.37	5.54e-13	GO:0065008	regulation of biological quality
1.76	5.58e-13	GO:0009887	organ morphogenesis
2.04	5.74e-13	GO:0007411	axon guidance
1.35	7.69e-13	GO:0048522	positive regulation of cellular process
1.86	8.61e-13	GO:0072358	cardiovascular system development
1.86	8.61e-13	GO:0072359	circulatory system development
1.56	5.53e-12	GO:0032879	regulation of localization
2.00	7.76e-12	GO:0044057	regulation of system process
1.78	1.86e-11	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.97	4.21e-11	GO:0045597	positive regulation of cell differentiation
1.26	1.37e-10	GO:0016043	cellular component organization
1.44	1.78e-10	GO:0035556	intracellular signal transduction
1.25	2.11e-10	GO:0031323	regulation of cellular metabolic process
1.23	2.41e-10	GO:0019222	regulation of metabolic process
1.25	2.67e-10	GO:0080090	regulation of primary metabolic process
1.17	7.44e-10	GO:0050896	response to stimulus
1.64	7.52e-10	GO:0009719	response to endogenous stimulus
1.52	9.45e-10	GO:0042127	regulation of cell proliferation
2.81	1.24e-09	GO:0001505	regulation of neurotransmitter levels
1.95	1.32e-09	GO:0022603	regulation of anatomical structure morphogenesis
1.29	1.85e-09	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.53	7.01e-09	GO:0040011	locomotion
1.24	7.85e-09	GO:0060255	regulation of macromolecule metabolic process
1.89	1.33e-08	GO:0060284	regulation of cell development
2.03	1.60e-08	GO:0007507	heart development
1.23	1.96e-08	GO:0071840	cellular component organization or biogenesis
1.94	2.04e-08	GO:0007423	sensory organ development
1.27	2.58e-08	GO:0031326	regulation of cellular biosynthetic process
1.52	2.64e-08	GO:0009888	tissue development
1.42	2.88e-08	GO:0010033	response to organic substance
1.27	3.38e-08	GO:0051171	regulation of nitrogen compound metabolic process
1.27	3.53e-08	GO:0071842	cellular component organization at cellular level
1.27	5.02e-08	GO:0009889	regulation of biosynthetic process
2.52	8.01e-08	GO:0006836	neurotransmitter transport
1.22	1.02e-07	GO:0051179	localization
2.10	1.14e-07	GO:0048732	gland development
1.91	1.19e-07	GO:0051960	regulation of nervous system development
1.60	1.23e-07	GO:0009725	response to hormone stimulus
1.55	1.45e-07	GO:0051049	regulation of transport
1.55	3.51e-07	GO:0009790	embryo development
1.57	3.65e-07	GO:0001932	regulation of protein phosphorylation
1.45	5.15e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.29	5.71e-07	GO:0006355	regulation of transcription, DNA-dependent
1.49	5.83e-07	GO:0051128	regulation of cellular component organization
1.55	6.92e-07	GO:0010628	positive regulation of gene expression
1.84	1.06e-06	GO:0001944	vasculature development
1.54	1.27e-06	GO:0042325	regulation of phosphorylation
1.44	1.30e-06	GO:0009605	response to external stimulus
1.78	1.65e-06	GO:0051093	negative regulation of developmental process
1.90	1.92e-06	GO:0050767	regulation of neurogenesis
1.87	2.09e-06	GO:0045596	negative regulation of cell differentiation
1.50	2.21e-06	GO:0006468	protein phosphorylation
1.23	2.28e-06	GO:0051234	establishment of localization
1.46	2.37e-06	GO:0006351	transcription, DNA-dependent
1.24	2.74e-06	GO:0071841	cellular component organization or biogenesis at cellular level
1.52	2.80e-06	GO:0019220	regulation of phosphate metabolic process
1.52	2.80e-06	GO:0051174	regulation of phosphorus metabolic process
1.27	2.93e-06	GO:0051252	regulation of RNA metabolic process
1.65	3.10e-06	GO:0010648	negative regulation of cell communication
1.82	3.11e-06	GO:0051270	regulation of cellular component movement
1.30	3.55e-06	GO:0006464	protein modification process
1.23	3.70e-06	GO:0006810	transport
1.42	3.85e-06	GO:0006793	phosphorus metabolic process
1.42	3.85e-06	GO:0006796	phosphate metabolic process
2.57	3.88e-06	GO:0008016	regulation of heart contraction
2.06	3.99e-06	GO:0030900	forebrain development
1.74	4.28e-06	GO:0007389	pattern specification process
2.17	5.05e-06	GO:0050678	regulation of epithelial cell proliferation
1.25	5.07e-06	GO:0010468	regulation of gene expression
1.60	5.18e-06	GO:0006935	chemotaxis
1.60	5.18e-06	GO:0042330	taxis
2.30	5.23e-06	GO:0050804	regulation of synaptic transmission
1.65	5.24e-06	GO:0023057	negative regulation of signaling
2.78	5.29e-06	GO:0007269	neurotransmitter secretion
2.02	5.38e-06	GO:0014070	response to organic cyclic compound
1.54	5.45e-06	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.77	7.28e-06	GO:0007610	behavior
1.62	7.48e-06	GO:0048646	anatomical structure formation involved in morphogenesis
1.25	7.56e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.53	8.29e-06	GO:0051172	negative regulation of nitrogen compound metabolic process
1.73	8.99e-06	GO:0043434	response to peptide hormone stimulus
1.51	9.49e-06	GO:0031327	negative regulation of cellular biosynthetic process
2.14	9.80e-06	GO:0031644	regulation of neurological system process
2.20	1.14e-05	GO:0051969	regulation of transmission of nerve impulse
1.64	1.46e-05	GO:0060341	regulation of cellular localization
2.61	1.65e-05	GO:0010721	negative regulation of cell development
1.24	1.69e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.49	1.77e-05	GO:0009890	negative regulation of biosynthetic process
2.28	2.14e-05	GO:0003001	generation of a signal involved in cell-cell signaling
2.28	2.14e-05	GO:0023061	signal release
1.56	2.42e-05	GO:0045892	negative regulation of transcription, DNA-dependent
1.73	3.05e-05	GO:0001501	skeletal system development
2.02	3.08e-05	GO:0001654	eye development
1.42	3.09e-05	GO:0006811	ion transport
1.55	3.17e-05	GO:0051253	negative regulation of RNA metabolic process
1.81	3.25e-05	GO:0030334	regulation of cell migration
1.40	3.69e-05	GO:0009892	negative regulation of metabolic process
1.32	3.70e-05	GO:0065009	regulation of molecular function
1.61	4.04e-05	GO:0006873	cellular ion homeostasis
1.74	4.77e-05	GO:0048729	tissue morphogenesis
1.62	4.78e-05	GO:0008285	negative regulation of cell proliferation
1.66	5.42e-05	GO:0048598	embryonic morphogenesis
2.15	5.58e-05	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.83	5.64e-05	GO:0003002	regionalization
1.51	6.00e-05	GO:0010629	negative regulation of gene expression
1.78	6.27e-05	GO:2000145	regulation of cell motility
1.78	6.56e-05	GO:0001568	blood vessel development
1.60	6.62e-05	GO:0032583	regulation of gene-specific transcription
1.64	6.64e-05	GO:0007264	small GTPase mediated signal transduction
1.62	6.70e-05	GO:0009968	negative regulation of signal transduction
2.12	6.80e-05	GO:0030111	regulation of Wnt receptor signaling pathway
1.55	7.43e-05	GO:0008284	positive regulation of cell proliferation
1.27	7.64e-05	GO:0043412	macromolecule modification
2.13	7.73e-05	GO:0022604	regulation of cell morphogenesis
1.41	8.47e-05	GO:0031324	negative regulation of cellular metabolic process
1.57	8.62e-05	GO:0050801	ion homeostasis
2.21	1.01e-04	GO:0007611	learning or memory
1.58	1.06e-04	GO:0055082	cellular chemical homeostasis
1.83	1.17e-04	GO:0002009	morphogenesis of an epithelium
1.33	1.19e-04	GO:0009893	positive regulation of metabolic process
1.90	1.22e-04	GO:0043408	regulation of MAPKKK cascade
1.71	1.25e-04	GO:0051130	positive regulation of cellular component organization
1.43	1.54e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
1.73	2.34e-04	GO:0061061	muscle structure development
1.62	2.57e-04	GO:0090066	regulation of anatomical structure size
1.46	2.66e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.42	2.85e-04	GO:0031399	regulation of protein modification process
1.53	3.06e-04	GO:0009967	positive regulation of signal transduction
2.07	3.11e-04	GO:0043010	camera-type eye development
1.79	3.38e-04	GO:0032868	response to insulin stimulus
1.99	3.61e-04	GO:0045165	cell fate commitment
1.51	3.65e-04	GO:0010647	positive regulation of cell communication
2.19	4.03e-04	GO:0010720	positive regulation of cell development
1.47	4.21e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.34	4.38e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.42	4.40e-04	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.84	4.41e-04	GO:0045664	regulation of neuron differentiation
1.54	4.63e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.94	5.11e-04	GO:0009952	anterior/posterior pattern formation
1.50	5.51e-04	GO:0023056	positive regulation of signaling
1.98	5.54e-04	GO:0001655	urogenital system development
1.46	5.57e-04	GO:0045893	positive regulation of transcription, DNA-dependent
1.66	5.76e-04	GO:0051046	regulation of secretion
1.53	5.84e-04	GO:0030001	metal ion transport
1.39	5.88e-04	GO:0016310	phosphorylation
1.60	5.89e-04	GO:0060429	epithelium development
1.60	5.92e-04	GO:0051056	regulation of small GTPase mediated signal transduction
1.51	6.18e-04	GO:0051338	regulation of transferase activity
1.69	6.30e-04	GO:0040012	regulation of locomotion
2.18	6.39e-04	GO:0021700	developmental maturation
1.46	6.51e-04	GO:0048878	chemical homeostasis
1.52	6.72e-04	GO:0043549	regulation of kinase activity
1.61	7.02e-04	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.51	7.41e-04	GO:0048585	negative regulation of response to stimulus
2.57	7.93e-04	GO:0050768	negative regulation of neurogenesis
1.82	8.26e-04	GO:0044087	regulation of cellular component biogenesis
1.37	8.65e-04	GO:0010605	negative regulation of macromolecule metabolic process
2.07	8.70e-04	GO:0050890	cognition
1.63	9.83e-04	GO:0032535	regulation of cellular component size
1.69	1.05e-03	GO:0035295	tube development
1.36	1.06e-03	GO:0032774	RNA biosynthetic process
2.27	1.11e-03	GO:0060828	regulation of canonical Wnt receptor signaling pathway
1.55	1.19e-03	GO:0040008	regulation of growth
1.57	1.27e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.43	1.28e-03	GO:0051254	positive regulation of RNA metabolic process
1.58	1.33e-03	GO:0009792	embryo development ending in birth or egg hatching
1.59	1.34e-03	GO:0043009	chordate embryonic development
1.71	1.38e-03	GO:0008361	regulation of cell size
2.36	1.58e-03	GO:0022612	gland morphogenesis
1.62	1.63e-03	GO:0015672	monovalent inorganic cation transport
1.53	1.73e-03	GO:0046903	secretion
1.51	1.76e-03	GO:0045859	regulation of protein kinase activity
1.76	1.85e-03	GO:0048514	blood vessel morphogenesis
1.31	1.88e-03	GO:0031325	positive regulation of cellular metabolic process
2.62	2.09e-03	GO:0090090	negative regulation of canonical Wnt receptor signaling pathway
1.46	2.44e-03	GO:0006812	cation transport
2.35	2.55e-03	GO:0048638	regulation of developmental growth
1.11	2.60e-03	GO:0044237	cellular metabolic process
1.65	2.66e-03	GO:0042493	response to drug
1.97	3.17e-03	GO:0048705	skeletal system morphogenesis
1.78	3.48e-03	GO:0003013	circulatory system process
1.78	3.48e-03	GO:0008015	blood circulation
1.98	3.69e-03	GO:0001763	morphogenesis of a branching structure
1.91	3.72e-03	GO:0046883	regulation of hormone secretion
2.05	3.78e-03	GO:0050796	regulation of insulin secretion
2.10	4.23e-03	GO:0043410	positive regulation of MAPKKK cascade
1.99	4.30e-03	GO:0010959	regulation of metal ion transport
1.61	4.46e-03	GO:0032940	secretion by cell
2.24	4.52e-03	GO:0030178	negative regulation of Wnt receptor signaling pathway
1.86	4.79e-03	GO:0006813	potassium ion transport
2.00	5.01e-03	GO:0002791	regulation of peptide secretion
2.00	5.01e-03	GO:0090087	regulation of peptide transport
1.59	5.14e-03	GO:0071495	cellular response to endogenous stimulus
2.76	5.14e-03	GO:0007613	memory
1.37	5.19e-03	GO:0048584	positive regulation of response to stimulus
2.52	5.45e-03	GO:0048593	camera-type eye morphogenesis
2.04	5.87e-03	GO:0072001	renal system development
1.92	6.02e-03	GO:0008286	insulin receptor signaling pathway
2.31	6.08e-03	GO:0050770	regulation of axonogenesis
1.88	6.14e-03	GO:0034762	regulation of transmembrane transport
2.21	6.46e-03	GO:0048592	eye morphogenesis
1.68	6.78e-03	GO:0040007	growth
1.99	7.71e-03	GO:0007265	Ras protein signal transduction
1.99	7.71e-03	GO:0090276	regulation of peptide hormone secretion
1.99	8.98e-03	GO:0060541	respiratory system development
2.19	9.14e-03	GO:0060485	mesenchyme development
1.70	9.18e-03	GO:0071375	cellular response to peptide hormone stimulus
1.82	9.65e-03	GO:0070482	response to oxygen levels
2.08	1.04e-02	GO:0030278	regulation of ossification
2.01	1.21e-02	GO:0048736	appendage development
2.01	1.21e-02	GO:0060173	limb development
1.84	1.26e-02	GO:0001666	response to hypoxia
2.43	1.32e-02	GO:0007612	learning
2.02	1.41e-02	GO:0001822	kidney development
3.43	1.45e-02	GO:0002027	regulation of heart rate
1.67	1.63e-02	GO:0048568	embryonic organ development
2.19	1.63e-02	GO:0050679	positive regulation of epithelial cell proliferation
2.00	1.87e-02	GO:0061138	morphogenesis of a branching epithelium
1.51	1.92e-02	GO:0010627	regulation of intracellular protein kinase cascade
1.36	1.95e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
2.39	2.02e-02	GO:0034765	regulation of ion transmembrane transport
1.43	2.06e-02	GO:0019725	cellular homeostasis
3.52	2.13e-02	GO:0046928	regulation of neurotransmitter secretion
2.79	2.20e-02	GO:0001952	regulation of cell-matrix adhesion
1.82	2.37e-02	GO:0031344	regulation of cell projection organization
2.06	2.53e-02	GO:0021537	telencephalon development
2.12	2.81e-02	GO:0055123	digestive system development
3.63	3.06e-02	GO:0007398	ectoderm development
1.79	3.13e-02	GO:0048562	embryonic organ morphogenesis
1.48	3.29e-02	GO:0007243	intracellular protein kinase cascade
1.48	3.29e-02	GO:0023014	signal transduction via phosphorylation event
1.91	3.40e-02	GO:0033273	response to vitamin
1.86	3.41e-02	GO:0042391	regulation of membrane potential
1.71	3.42e-02	GO:0006874	cellular calcium ion homeostasis
2.42	3.49e-02	GO:0032412	regulation of ion transmembrane transporter activity
2.81	3.58e-02	GO:0042733	embryonic digit morphogenesis
2.10	3.86e-02	GO:0007160	cell-matrix adhesion
2.00	3.92e-02	GO:0003007	heart morphogenesis
2.17	4.12e-02	GO:2000027	regulation of organ morphogenesis
3.77	4.25e-02	GO:0048048	embryonic eye morphogenesis
3.09	4.31e-02	GO:0051588	regulation of neurotransmitter transport
2.11	4.42e-02	GO:0050769	positive regulation of neurogenesis
5.14	4.74e-02	GO:0060687	regulation of branching involved in prostate gland morphogenesis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.45	4.33e-21	GO:0044459	plasma membrane part
1.43	2.06e-10	GO:0031226	intrinsic to plasma membrane
1.43	3.27e-10	GO:0005887	integral to plasma membrane
1.08	1.85e-08	GO:0044424	intracellular part
1.08	3.33e-08	GO:0005622	intracellular
1.71	4.31e-08	GO:0045202	synapse
1.47	8.59e-08	GO:0042995	cell projection
1.47	1.07e-07	GO:0005626	insoluble fraction
1.69	1.55e-07	GO:0043005	neuron projection
1.40	2.15e-07	GO:0000267	cell fraction
1.47	3.31e-07	GO:0005624	membrane fraction
1.18	7.99e-07	GO:0005886	plasma membrane
1.18	9.30e-07	GO:0071944	cell periphery
1.43	6.42e-06	GO:0031982	vesicle
1.04	1.04e-05	GO:0044464	cell part
1.04	1.11e-05	GO:0005623	cell
1.44	1.31e-05	GO:0031988	membrane-bounded vesicle
2.02	4.80e-05	GO:0034703	cation channel complex
1.66	8.85e-05	GO:0044456	synapse part
1.41	9.36e-05	GO:0016023	cytoplasmic membrane-bounded vesicle
1.39	1.44e-04	GO:0031410	cytoplasmic vesicle
1.55	3.63e-04	GO:0031012	extracellular matrix
1.81	3.92e-04	GO:0030424	axon
1.09	4.34e-04	GO:0005737	cytoplasm
2.09	4.84e-04	GO:0019898	extrinsic to membrane
1.73	5.50e-04	GO:0034702	ion channel complex
1.42	6.13e-04	GO:0030054	cell junction
2.18	6.69e-04	GO:0030665	clathrin coated vesicle membrane
1.82	9.05e-04	GO:0030136	clathrin-coated vesicle
2.13	1.30e-03	GO:0008021	synaptic vesicle
2.70	1.88e-03	GO:0043679	axon terminus
2.57	5.13e-03	GO:0044306	neuron projection terminus
2.84	1.24e-02	GO:0034704	calcium channel complex
1.44	1.72e-02	GO:0044463	cell projection part
1.06	2.26e-02	GO:0043226	organelle
1.62	2.36e-02	GO:0030135	coated vesicle
2.03	2.61e-02	GO:0033267	axon part
1.95	2.88e-02	GO:0008076	voltage-gated potassium channel complex
1.95	2.88e-02	GO:0034705	potassium channel complex
1.87	3.80e-02	GO:0019717	synaptosome
1.79	4.87e-02	GO:0030662	coated vesicle membrane
1.06	4.96e-02	GO:0043229	intracellular organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.11	5.25e-23	GO:0005488	binding
1.20	3.30e-22	GO:0005515	protein binding
1.51	7.75e-11	GO:0001071	nucleic acid binding transcription factor activity
1.51	7.75e-11	GO:0003700	sequence-specific DNA binding transcription factor activity
1.58	2.65e-09	GO:0043565	sequence-specific DNA binding
1.43	1.93e-07	GO:0030528	transcription regulator activity
1.83	5.94e-07	GO:0005261	cation channel activity
1.49	8.41e-07	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.46	1.50e-06	GO:0016301	kinase activity
2.54	1.58e-06	GO:0019199	transmembrane receptor protein kinase activity
1.52	2.20e-06	GO:0004672	protein kinase activity
1.54	4.29e-06	GO:0008324	cation transmembrane transporter activity
1.73	5.51e-06	GO:0022836	gated channel activity
2.31	6.53e-06	GO:0005057	receptor signaling protein activity
1.40	1.23e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.56	2.01e-05	GO:0060589	nucleoside-triphosphatase regulator activity
1.90	2.24e-05	GO:0005244	voltage-gated ion channel activity
1.90	2.24e-05	GO:0022832	voltage-gated channel activity
1.44	2.67e-05	GO:0015075	ion transmembrane transporter activity
2.03	3.36e-05	GO:0022843	voltage-gated cation channel activity
1.55	3.87e-05	GO:0030695	GTPase regulator activity
1.58	4.43e-05	GO:0022803	passive transmembrane transporter activity
1.57	7.14e-05	GO:0015267	channel activity
1.32	8.85e-05	GO:0005215	transporter activity
2.53	1.22e-04	GO:0004714	transmembrane receptor protein tyrosine kinase activity
1.57	1.38e-04	GO:0022838	substrate-specific channel activity
1.35	1.57e-04	GO:0022892	substrate-specific transporter activity
1.36	1.71e-04	GO:0022857	transmembrane transporter activity
1.69	1.86e-04	GO:0032403	protein complex binding
1.37	1.91e-04	GO:0022891	substrate-specific transmembrane transporter activity
1.57	1.92e-04	GO:0005216	ion channel activity
1.24	2.03e-04	GO:0032553	ribonucleotide binding
1.24	2.03e-04	GO:0032555	purine ribonucleotide binding
1.21	2.83e-04	GO:0003677	DNA binding
1.24	2.92e-04	GO:0017076	purine nucleotide binding
1.93	8.60e-04	GO:0004713	protein tyrosine kinase activity
1.23	1.22e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.50	1.27e-03	GO:0004674	protein serine/threonine kinase activity
1.60	1.86e-03	GO:0008134	transcription factor binding
1.20	2.13e-03	GO:0000166	nucleotide binding
2.63	2.29e-03	GO:0046332	SMAD binding
2.20	2.61e-03	GO:0005262	calcium channel activity
3.16	3.43e-03	GO:0005245	voltage-gated calcium channel activity
1.36	3.47e-03	GO:0019899	enzyme binding
1.56	4.70e-03	GO:0016564	transcription repressor activity
1.64	5.09e-03	GO:0019900	kinase binding
1.88	6.81e-03	GO:0005267	potassium channel activity
1.23	6.91e-03	GO:0032559	adenyl ribonucleotide binding
1.54	8.38e-03	GO:0016563	transcription activator activity
1.23	8.58e-03	GO:0030554	adenyl nucleotide binding
1.81	1.06e-02	GO:0005516	calmodulin binding
1.45	1.06e-02	GO:0019904	protein domain specific binding
1.30	1.20e-02	GO:0030234	enzyme regulator activity
1.65	1.38e-02	GO:0000975	regulatory region DNA binding
1.65	1.38e-02	GO:0001067	regulatory region nucleic acid binding
1.65	1.38e-02	GO:0044212	transcription regulatory region DNA binding
1.13	2.00e-02	GO:0046872	metal ion binding
1.64	2.73e-02	GO:0010843	promoter binding
1.32	2.80e-02	GO:0042802	identical protein binding
1.71	2.87e-02	GO:0005085	guanyl-nucleotide exchange factor activity
1.38	3.18e-02	GO:0008092	cytoskeletal protein binding
1.55	4.12e-02	GO:0005096	GTPase activator activity
1.44	4.15e-02	GO:0008047	enzyme activator activity
1.20	4.16e-02	GO:0016740	transferase activity
1.21	4.34e-02	GO:0005524	ATP binding
1.12	4.68e-02	GO:0043169	cation binding